Staff Profiles

Dr Andrew Daly

B.A., B.A.I, Ph.D

Contact Details

Lecturer Above The Bar
E: andrew.daly@universityofgalway.ie

Biography

Dr Daly is an Assistant Professor in Biomedical Engineering at the University of Galway. His research focuses on bioprinting tissue and organ models with advanced physiological structure and function. In particular, this work focuses on developing bioprinting technologies inspired by organogenesis.

Dr Daly was awarded a PhD in Mechanical Engineering from Trinity College Dublin in 2018, where he developed bioprinted implants for joint resurfacing. For this work, he was awarded the Engineer's Ireland Biomedical Engineering Research Medal in 2018. Following this, he moved to the Department of Bioengineering at the University of Pennsylvania for his postdoctoral training. In 2020, he was awarded an American Heart Association Postdoctoral Fellowship to develop bioprinted cardiac disease models for screening of miRNA therapeutics. In January 2021, he started his research group at the University of Galway and in 2022 he was awarded a European Research Council Starting Grant.

Dr Daly's research is highly cited and has been published in the top journals in the field, including Nature Communications, Nature Reviews Materials, Cell, Biomaterials, Advanced Science, Acta Biomaterialia, Advanced Healthcare Materials, and Biofabrication. To date, he has has received over 1.8 million euro in research funding.

Link to publications
https://scholar.google.com/citations?user=6aab09cAAAAJ&hl=en

Link to personal research webpage
https://www.biofabrication.ie/

Research Career:

2021 - present: Assistant Professor in Biomedical Engineering, College of Science and Engineering, NUI Galway

2021 - present: Funded Investigator at CÚRAM - Science Foundation Ireland Research Centre for Medical Devices

2018 - 2021: American Heart Association Postdoctoral Fellow, University of Pennsylvania, Philadelphia, USA

2013 - 2017: PhD in Biomedical Engineering, Trinity Centre for Bioengineering, Trinity College Dublin, Ireland

Research Interests

Research Overview
Our work focuses on developing enabling technologies for organ bioprinting. In particular, we create developmentally inspired bioprinting approaches leveraging embryonic processes such as stem cell condensation and tissue fusion. We are currently developing dynamic hydrogels that can program and scale these fundamental behaviours to engineer organs with advanced structural and functional properties.

Example publications
Bioprinted Tissue Models
https://www.nature.com/articles/s41467-021-21029-2
https://www.sciencedirect.com/science/article/abs/pii/S009286742031624X

Granular Hydrogels
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201801076
https://www.nature.com/articles/s41578-019-0148-6
https://www.sciencedirect.com/science/article/abs/pii/S1742706120306383

Cartilage and Bone Bioprinting
https://www.sciencedirect.com/science/article/abs/pii/S0142961218308639
https://iopscience.iop.org/article/10.1088/1758-5090/8/4/045002/meta
https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.201600182
https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.201700298
https://www.sciencedirect.com/science/article/abs/pii/S0142961218300772

Research Projects

	Project	Start Date	End Date
	ERC Starting Grant - morphoPRINT	01-MAY-23	30-APR-28
	Science Foundation Ireland Future Digital Challenge - aiPRINT	01-JAN-23	30-DEC-24

Contract Researchers

Researcher Name	Project	Role
Dr Juhi Chakraborty	ERC Starting Grant	Postdoctoral Researcher
Dr Daniel Kelly	Science Foundation Ireland Future Digital Challenge - aiPRINT	Postdoctoral Researcher
Dr Rashmi Ramakrishnan	CÚRAM Industry co-fund	Postdoctoral Researcher
Dr Vasileios (Vasilis) Sergis	Science Foundation Ireland Future Digital Challenge - aiPRINT	Postdoctoral Researcher

Peer Reviewed Journals

	Year	Publication
	(2024)	'Injectable MSC Spheroid and Microgel Granular Composites for Engineering Tissue' Nikolas Di Caprio, Matthew D. Davidson, Andrew C. Daly, Jason A. Burdick (2024) 'Injectable MSC Spheroid and Microgel Granular Composites for Engineering Tissue'. Advanced Materials, [DOI] [Details]
	(2023)	'High resolution lithography 3D bioprinting' Andrew C. Daly, Khoon S. Lim (2023) 'High resolution lithography 3D bioprinting'. Trends In Biotechnology, [Details]
	(2023)	'Granular Hydrogels in Biofabrication: Recent Advances and Future Perspectives' Andrew C. Daly (2023) 'Granular Hydrogels in Biofabrication: Recent Advances and Future Perspectives'. Advanced Healthcare Materials, [Details]
	(2021)	'Bioprinting for the Biologist' Daly, Andrew C.,Prendergast, Margaret E.,Hughes, Alex J.,Burdick, Jason A. (2021) 'Bioprinting for the Biologist'. Cell, 184 (1):18-32 [Details]
	(2021)	'3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels' Daly, Andrew., Davidson, Matthew. D., Burdick, Jason.A. (2021) '3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels'. Nature Communications, [Details]
	(2021)	'Injectable hyaluronic acid and platelet lysate-derived granular hydrogels for biomedical applications' Mendes, BÃ¡rbara B.,Daly, Andrew C.,Reis, Rui L.,Domingues, Rui M.A.,Gomes, Manuela E.,Burdick, Jason A. (2021) 'Injectable hyaluronic acid and platelet lysate-derived granular hydrogels for biomedical applications'. Acta Biomaterialia, 119 :101-113 [Details]
	(2020)	'Hydrogel microparticles for biomedical applications' Daly, Andrew C.,Riley, Lindsay,Segura, Tatiana,Burdick, Jason A. (2020) 'Hydrogel microparticles for biomedical applications'. Nature Reviews Materials, 5 (1):20-43 [Details]
	(2020)	'The bioprinting roadmap' Sun, Wei,Starly, Binil,Daly, Andrew C,Burdick, Jason A,Groll, JÃ¼rgen,Skeldon, Gregor,Shu, Wenmiao,Sakai, Yasuyuki,Shinohara, Marie,Nishikawa, Masaki,Jang, Jinah,Cho, Dong-Woo,Nie, Minghao,Takeuchi, Shoji,Ostrovidov, Serge,Khademhosseini, Ali,Kamm, Roger D,Mironov, Vladimir,Moroni, Lorenzo,Ozbolat, Ibrahim T (2020) 'The bioprinting roadmap'. Biofabrication, 12 (2) [Details]
	(2019)	'Jammed Microgel Inks for 3D Printing Applications' Highley, Christopher B.,Song, Kwang Hoon,Daly, Andrew C.,Burdick, Jason A. (2019) 'Jammed Microgel Inks for 3D Printing Applications'. Advanced Science, 6 (1) [Details]
	(2019)	'Hypoxia mimicking hydrogels to regulate the fate of transplanted stem cells' Sathy, Binulal N.,Daly, Andrew,Gonzalez-Fernandez, Tomas,Olvera, Dinorath,Cunniffe, Grainne,McCarthy, Helen O.,Dunne, Nicholas,Jeon, Oju,Alsberg, Eben,Donahue, Tammy L. Haut,Kelly, Daniel J. (2019) 'Hypoxia mimicking hydrogels to regulate the fate of transplanted stem cells'. Acta Biomaterialia, 88 :314-324 [Details]
	(2019)	'Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers' Daly, Andrew C.,Kelly, Daniel J. (2019) 'Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers'. Biomaterials, 197 :194-206 [Details]
	(2018)	'Engineering large cartilage tissues using dynamic bioreactor culture at defined oxygen conditions' Daly, Andrew C,Sathy, Binulal N,Kelly, Daniel J (2018) 'Engineering large cartilage tissues using dynamic bioreactor culture at defined oxygen conditions'. Journal of Tissue Engineering, 9 [Details]
	(2018)	'3D printed microchannel networks to direct vascularisation during endochondral bone repair' Daly, Andrew C.,Pitacco, Pierluca,Nulty, Jessica,Cunniffe, GrÃ¡inne M.,Kelly, Daniel J. (2018) '3D printed microchannel networks to direct vascularisation during endochondral bone repair'. Biomaterials, 162 :34-46 [Details]
	(2017)	'Three-Dimensional Bioprinting of Polycaprolactone Reinforced Gene Activated Bioinks for Bone Tissue Engineering' Cunniffe, GrÃ¡inne M.,Gonzalez-Fernandez, Tomas,Daly, Andrew,Sathy, Binulal N.,Jeon, Oju,Alsberg, Eben,Kelly, Daniel J. (2017) 'Three-Dimensional Bioprinting of Polycaprolactone Reinforced Gene Activated Bioinks for Bone Tissue Engineering'. Tissue Engineering Part A, 23 (17-18):891-900 [Details]
	(2017)	'3D Bioprinting for Cartilage and Osteochondral Tissue Engineering' Daly, Andrew C.,Freeman, Fiona E.,Gonzalez-Fernandez, Tomas,Critchley, Susan E.,Nulty, Jessica,Kelly, Daniel J. (2017) '3D Bioprinting for Cartilage and Osteochondral Tissue Engineering'. Advanced Healthcare Materials, 6 (22) [Details]
	(2016)	'3D Bioprinting of Developmentally Inspired Templates for Whole Bone Organ Engineering' Daly, Andrew C.,Cunniffe, GrÃ¡inne M.,Sathy, Binulal N.,Jeon, Oju,Alsberg, Eben,Kelly, Daniel J. (2016) '3D Bioprinting of Developmentally Inspired Templates for Whole Bone Organ Engineering'. Advanced Healthcare Materials, 5 (18):2353-2362 [Details]
	(2016)	'A comparison of different bioinks for 3D bioprinting of fibrocartilage and hyaline cartilage' Daly, Andrew C,Critchley, Susan E,Rencsok, Emily M,Kelly, Daniel J (2016) 'A comparison of different bioinks for 3D bioprinting of fibrocartilage and hyaline cartilage'. Biofabrication, 8 (4) [Details]
	(2014)	'Shape-memory porous alginate scaffolds for regeneration of the annulus fibrosus: Effect of TGF-Î²3 supplementation and oxygen culture conditions' Guillaume, Olivier,Daly, Andrew,Lennon, Kerri,Gansau, Jennifer,Buckley, Shane F.,Buckley, Conor T. (2014) 'Shape-memory porous alginate scaffolds for regeneration of the annulus fibrosus: Effect of TGF-Î²3 supplementation and oxygen culture conditions'. Acta Biomaterialia, 10 (5):1985-1995 [Details]

Other Journals

	Year	Publication
	(2022)	'Bioprinting in granular support hydrogels - characterizing the role of particle morphology and packing density' Graham Britchfield, Andrew C. Daly (2022) 'Bioprinting in granular support hydrogels - characterizing the role of particle morphology and packing density' bioRxiv, . [DOI] [Details]
	(2022)	'An interdisciplinary framework for the characterization of extracellular matrix-hydrogels for biomedical applications' Sergio Martin-Saldaña, Mansoor Al Waeel, Amir M Alsharabasy, Andrew Daly, Abhay Pandit (2022) 'An interdisciplinary framework for the characterization of extracellular matrix-hydrogels for biomedical applications' Matter, . [DOI] [Details]

Honours and Awards

Year	Title	Awarding Body
2023	European Research Council Starting Grant	European Research Council
2019	American Heart Association Postdoctoral Fellowship	American Heart Association
2019	STAR Abstract Award, Society for Biomaterials	Society for Biomaterials
2019	Biofabrication Journal Outstanding Reviewer Award	Biofabrication Journal
2017	Article "A comparison of different bioinks for 3D bioprinting of fibrocartilage and hyaline cartilage¿ chosen as part of Biofabrication Journal "Highlights of 2016"	Biofabrication Journal
2017	Engineer's Ireland Biomedical Engineering Research Medal	Engineers Ireland

Professional Associations

	Association	Function	From / To
	Society for Biomaterials	Member	01-MAR-19 / 01-FEB-21
	International Society for Biofabrication	Early Career Researcher Committee Chair	01-MAY-20 / 01-FEB-21

Teaching Interests

Biomaterials, Hydrogels, Bioprinting, Additive Manufacturing, Cell material interactions, Mechanobiology

Current Postgraduate Students (Research)

Student	Degree Type	Type
Sogol Kianersi	Doctorate - Structured Ph.D (Engineering)	Supervisor
Ankita Pramanick	Doctorate - Structured Ph.D (Engineering)	Supervisor
Hannah Aris	Doctorate - Structured Ph.D (Engineering)	Co-supervisor (2)

Modules Taught

Term/Year	Module Title	Module Code
Semester 2	Fundamentals of Engineering	EI140
Semester 2	Introduction to Biomaterials	BME200
Semester 1	Principles of Biomaterials	BME328
Semester 2	Mechanobiology	BME5101