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About University of Galway
About University of Galway
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Guiding Breakthrough Research at University of Galway
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Accessibility & LanguageResearch
We Combine the expertise of NJUCM in traditional Chinese medicine with NUI Galway's expertise in stem cell biology.
Research Programme- Merging Chinese Medicine and Regenerative Medicine
The research programme will aim to identify the regenerative properties of Chinese Medicines including the effects on stem cell biology.
Global education, scientific research and clinical trials of Chinese Medicine are all needed to enable a worldwide translation of Chinese Medicine products. The University of Galway and NJUCM through the foundation of this Confucius institute will enable collaborative research to be undertaken.
This research will occur in parallel with the education and application of Chinese Medicine to practice in Ireland.
There are over 500 Confucius Institutes worldwide most focusing on the education of Chinese Language & Culture, and 10 are involved in Chinese Medicine Education.
The Confucius Institute at the University of Galway is the only one involved in teaching and research in Chinese Medicine and Regenerative Medicine as well as Language and Culture.
The CI at the University of Galway is developing research agreements and material transfer agreements (MTAs) to allow research cooperation and material transfer between the two universities to allow joint research and detailed collaboration going forward in Chinese and Regenerative Medicine.
The expertise at Galway in Stem cell manipulation together with the expertise at NJUCM in Traditional Chinese Medicine will allow the submission of joint funding proposals to European and Chinese research agencies. Plans are already underway for some initial research to input into these research funding grant applications. Panels of Chinese Medicine compounds are available from NJUCM that can be analysed by high throughput in vitro screening protocols already established at the University of Galway for indicators of efficacy. Shortlisted candidate compounds will be analysed by in vivo pre-clinical animal models to establish and confirm in vivo efficacy in stem cell iPS models of ALS, autism and sudden cardiac death.
The Regenerative Medicine Institute at The University of Galway
The Regenerative Medicine Institute (REMEDI) is a world-class biomedical research centre focusing on gene therapy and stem cell research. We are a partnership involving scientists, clinicians, and engineers in academic centres and in industry. Researchers at REMEDI work together to combine the technologies of gene therapy and adult stem cell therapy with the aim of regeneration and repair of tissues.
Professor Timothy O'Brien is a co-founder and Director of REMEDI, the Regenerative Medicine Institute at the University of Galway.
REMEDI are involved in a number of key research areas:
Stem cell biology
This programme involves the research and use of adult human stem cells for therapeutic benefit. Research programmes at REMEDI will initially focus on the behaviour of mesenchymal stem cells and refine techniques to isolate and grow them. More importantly, researchers will investigate the factors that induce or coax stem cells to differentiate into different cell types.
Gene therapy
REMEDI researchers are focussing on the genetic modification of cells or tissues to promote tissue regeneration and/or repair for the treatment of severe diseases such as myocardial infarction, osteoarthritis and spinal cord injury.
Orthobiologics
The aim of this programme is to develop novel stem cell-based therapeutics for osteoarthritis and cartilage repair. Our goal is to develop these therapies using adult bone marrow stem cells to promote the regrowth of healthy cartilage and repair damaged joints.
Immunology
This programme involves assessing the host immune response to stem cell and gene therapy. Understanding how the body's immune system responds to transplanted cells and genes is critical in developing new therapeutic strategies.
Cardiovascular
The aim of this programme is to develop novel therapeutic approaches for the treatment of atherosclerotic vascular diseases. The major areas of research are in the use of mesenchymal stem cells and endothelial progenitor cells for cardiac and vascular repair, the development of medical devices for stem cell administration, the use of biomaterials for stem cell delivery in cardiovascular disease and understanding the pathogenesis of the diabetic vascular disease.
Socioeconomic and bioethical research
This programme involves the socio-economic and bioethical aspects of stem cell and gene therapy research and explores ethical issues and socio-economic determinants and impacts in the fields of stem cell and gene therapy research.
Centre for Cell Manufacturing Ireland
The Centre for Cell Manufacturing Ireland, based at the University of Galway, is the first and only approved facility on the Island of Ireland. The custom-built licensed centre is designed to manufacture Advanced Therapeutic Medicinal Products such as stem cells for use in human clinical trials. Cellular therapy is not a technology of the future, it is having an impact now, with thousands of ongoing clinical trials using stem cells as the preferred treatment option.
This is a dedicated facility to produce cellular therapeutic products such as adenoviral vectors and adult mesenchymal stem cells, according to current Good Manufacturing Practice (GMP). Professor Timothy O'Brien is a director of the CCMI. Find out more.
