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Dr Meadhbh Brennan

Biography

Dr. Meadhbh Brennan is a Galway University Foundation Senior Research Lecturer in Biomedical Engineering and Regenerative Medicine with a co-appointment between the School of Medicine and the School of Engineering at NUIG. She joined the Regenerative Medicine Institute (REMEDI) in 2020. Her interdisciplinary research focuses on the therapeutic potential of mesenchymal stem/stromal cells (MSCs) and their secretome, with a particular interest in tissue engineering, mechanobiology, and bone repair.

Dr. Brennan earned her Ph.D. and B.Eng. degrees in Biomedical Engineering from the University of Southampton, and NUIG, respectively. From 2017 to 2020, she was a Marie Skłodowska Curie global fellow in Prof. Mooney's laboratory at the School of Engineering and Applied Sciences (SEAS) at Harvard University, she also conducted research in the Breakefield lab at MGH, Harvard Medical School. Prior to this she was a postdoctoral researcher in INSERM, Faculty of Medicine, Nantes, France.

Research currently ongoing in Dr. Brennan’s group is centred on MSC‐secreted factors, particularly extracellular vesicles (EVs) and the physical and chemical cues that can regulate their secretion and immunomodulatory roles. Her team’s research goals also include uncovering the mechanisms underpinning EV action on cells involved in the tissue healing cascade, and the development of therapeutic EV delivery strategies using biomaterials. Her current research is funded by a European Research Council (ERC) Starting grant, and a Science Foundation Ireland (SFI) Starting Investigator Research Award (SIRG) award.

Please see here for research publications. Furthermore, for details on our current research endeavours please see our research group page here.