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Dr Siobhan McMahon

B.Sc., Ph.D.

 
researcher
 

Biography

Dr Siobhan McMahon is an Assistant Professor and Neuroscientist in Anatomy at University of Galway.  Dr McMahon is Deputy Director of the Galway Neuroscience Centre and s a founding member of the Global Neuroanatomy Network,  Dr McMahon was awarded her BSc in Biology from Maynooth University in 1994. She was awarded her Ph.D. in 2000 from University College Cork where she investigated the differentiation of radial glial in the developing spinal cord. She continued her research in University College Cork as a postdoctoral research fellow investigating the lineage potential of glial cells in the developing spinal cord. In 2005 she joined the Regenerative Medicine Institute at University of Galway as a Health Research Board funded postdoctoral fellow. Her research then focused on the use of lentiviral vectors to treat injury in the central nervous system. In November 2006 she joined the Discipline of Anatomy at University of Galway as a lecturer . Her research currently involves use of stem cells, viral vectors and polymer scaffolds to promote regeneration following spinal cord injury.  Dr McMahon has supervised 6 PhD students to completion and has mentored postdoctoral scientists. She hosts MSc students, and undergraduate research students annually. Dr McMahon is actively involved in science outreach to school children and the general public.

Research Interests

spinal cord repair, glial scarring, neurotrophic factors, developmental neurobiology, stem cell biology, gene therapy, scaffolds for spinal cord tissue engineering.

Pubmed link: https://pubmed.ncbi.nlm.nih.gov/?term=mcmahon+ss+cork+OR+mcmahon+ss+galway+OR+mcmahon+s+galway

ResearchGate:  https://www.researchgate.net/profile/Siobhan-Mcmahon

Google Scholar:   https://scholar.google.com/citations?hl=en&user=GnVbNFgAAAAJ&view_op=list_works&sortby=pubdate

Peer Reviewed Journals

  Year Publication
(2023) 'Models and approaches to comprehend and address glial inflammation following spinal cord injury'
V Patil, R Bohara, VK Kanala, S McMahon, A Pandit. (2023) 'Models and approaches to comprehend and address glial inflammation following spinal cord injury'. Drug Discovery Today, 28 (10) [DOI] [Details]
(2023) 'An insight into new glycotherapeutics in glial inflammation: Understanding the role of glycosylation in mitochondrial function and acute to the chronic phases of inflammation'
Patil, V; Bohara, R; Winter, C; Kilcoyne, M; McMahon, S; Pandit, A (2023) 'An insight into new glycotherapeutics in glial inflammation: Understanding the role of glycosylation in mitochondrial function and acute to the chronic phases of inflammation'. Cns Neuroscience & Therapeutics, 29 (1):429-444 [DOI] [Details]
(2022) 'Distinct Glycosylation Responses to Spinal Cord Injury in Regenerative and Nonregenerative Models'
Ronan, R; Kshirsagar, A; Rebelo, AL; Sunny, A; Kilcoyne, M; O¿ Flaherty, R; Rudd, PM; Schlosser, G; Saldova, S; Pandit, A; McMahon, SS (2022) 'Distinct Glycosylation Responses to Spinal Cord Injury in Regenerative and Nonregenerative Models'. Journal Of Proteome Research, 21 (6):1449-1466 [DOI] [Details]
(2021) 'Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury'
Shortiss, C; Howard, L; McMahon S (2021) 'Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury'. Cells, [DOI] [Details]
(2021) 'A Robust Platform for High-throughput Screening of Therapeutic Strategies for Acute and Chronic Spinal Cord Injury'
Patil V; O'Connell E; Quinlan L; Fearnhead H; McMahon S; Pandit A (2021) 'A Robust Platform for High-throughput Screening of Therapeutic Strategies for Acute and Chronic Spinal Cord Injury'. Iscience, [Details]
(2020) 'Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2'
Patar A;Dockery P;McMahon S;Howard L; (2020) 'Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2'. Biology, 9 (3) [DOI] [Details]
(2019) 'Differential Glycosylation Expression in Injured Rat Spinal Cord Treated with Immunosuppressive Drug Cyclosporin-A'
Kilcoyne M;Patil V;O'Grady C;Bradley C;McMahon SS; (2019) 'Differential Glycosylation Expression in Injured Rat Spinal Cord Treated with Immunosuppressive Drug Cyclosporin-A'. Acs Omega, 4 (2) [DOI] [ARAN Link] [Details]
(2019) 'Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury'
Patar, A,Dockery, P,Howard, L,McMahon, S (2019) 'Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury'. Journal Of Neuroscience Methods, 311 :418-425 [DOI] [ARAN Link] [Details]
(2019) 'Cell viability in three ex vivo rat models of spinal cord injury'
Patar, A,Dockery, P,Howard, L,McMahon, SS (2019) 'Cell viability in three ex vivo rat models of spinal cord injury'. Journal Of Anatomy, 234 :244-251 [DOI] [ARAN Link] [Details]
(2018) 'GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats'
Chen, BK,Madigan, NN,Hakim, JS,Dadsetan, M,McMahon, SS,Yaszemski, MJ,Windebank, AJ (2018) 'GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats'. Journal Of Tissue Engineering And Regenerative Medicine, 12 :398-407 [DOI] [ARAN Link] [Details]
(2017) 'Therapeutic Effect of Neurotrophin-3 Treatment in an Injectable Collagen Scaffold Following Rat Spinal Cord Hemisection Injury'
Breen, BA,Kraskiewicz, H,Ronan, R,Kshiragar, A,Patar, A,Sargeant, T,Pandit, A,McMahon, SS (2017) 'Therapeutic Effect of Neurotrophin-3 Treatment in an Injectable Collagen Scaffold Following Rat Spinal Cord Hemisection Injury'. ACS Biomaterials Science & Engineering, 3 :1287-1295 [DOI] [ARAN Link] [Details]
(2016) 'NON-VIRAL XYLOSYLTRANSFERASE-1 siRNA DELIVERY AS AN EFFECTIVE ALTERNATIVE TO CHONDROITINASE IN AN IN VITRO MODEL OF REACTIVE ASTROCYTES'
Abu-Rub, MT,Newland, B,Naughton, M,Wang, WX,Mcmahon, S,Pandit, A (2016) 'NON-VIRAL XYLOSYLTRANSFERASE-1 siRNA DELIVERY AS AN EFFECTIVE ALTERNATIVE TO CHONDROITINASE IN AN IN VITRO MODEL OF REACTIVE ASTROCYTES'. Neuroscience, 339 :267-275 [DOI] [ARAN Link] [Details]
(2014) 'Comparison of Cellular Architecture, Axonal Growth, and Blood Vessel Formation Through Cell-Loaded Polymer Scaffolds in the Transected Rat Spinal Cord'
Madigan, NN,Chen, BK,Knight, AM,Rooney, GE,Sweeney, E,Kinnavane, L,Yaszemski, MJ,Dockery, P,O'Brien, T,McMahon, SS,Windebank, AJ (2014) 'Comparison of Cellular Architecture, Axonal Growth, and Blood Vessel Formation Through Cell-Loaded Polymer Scaffolds in the Transected Rat Spinal Cord'. Tissue Engineering Part A, 20 :2985-2997 [DOI] [ARAN Link] [Details]
(2013) 'Assembly of Protein-based Hollow Spheres Encapsulating a Therapeutic Factor'
Kraskiewicz H, Breen B, Sargeant T, McMahon S, Pandit A (2013) 'Assembly of Protein-based Hollow Spheres Encapsulating a Therapeutic Factor'. Acs Chemical Neuroscience, [DOI] [ARAN Link] [Details]
(2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'
Donnelly EM, Madigan NN, Rooney GE, Knight A, Chen B, Ball B, Kinnavane L, Garcia Y, Dockery P, Fraher J, Strappe PM, Windebank AJ, O'Brien T, McMahon SS (2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'. Cytotherapy, 14 (10):1235-1244 [DOI] [Details]
(2012) 'Neuronal glycosylation differentials in normal, injured and chondroitinase-treated environments'
Kilcoyne, M,Sharma, S,McDevitt, N,O'Leary, C,Joshi, L,McMahon, SS (2012) 'Neuronal glycosylation differentials in normal, injured and chondroitinase-treated environments'. Biochemical And Biophysical Research Communications, 420 :616-622 [DOI] [ARAN Link] [Details]
(2011) 'Nano-textured self-assembled aligned collagen hydrogels promote directional neurite guidance and overcome inhibition by myelin associated glycoprotein'
Abu-Rub, MT and Billiar, KL and van Es, MH and Knight, A and Rodriguez, BJ and Zeugolis, DI and McMahon, S and Windebank, AJ and Pandit, A (2011) 'Nano-textured self-assembled aligned collagen hydrogels promote directional neurite guidance and overcome inhibition by myelin associated glycoprotein'. Soft Matter, 7 (6):2770-2781 [Details]
(2011) 'Thermosensitive hydrogel for prolonged delivery of lentiviral vector expressing neurotrophin-3 in vitro'
McMahon, SS,Nikolskaya, N,Choileain, SN,Hennessy, N,O'Brien, T,Strappe, PM,Gorelov, A,Rochev, Y (2011) 'Thermosensitive hydrogel for prolonged delivery of lentiviral vector expressing neurotrophin-3 in vitro'. Journal Of Gene Medicine, 13 :591-601 [DOI] [ARAN Link] [Details]
(2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'
McMahon, SS,Albermann, S,Rooney, GE,Shaw, G,Garcia, Y,Sweeney, E,Hynes, J,Dockery, P,O'Brien, T,Windebank, AJ,Allsopp, TE,Barry, FP (2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'. Cytotherapy, 12 :313-325 [DOI] [ARAN Link] [Details]
(2010) 'Spinal cord injury in vitro: modelling axon growth inhibition. '
Abu-Rub M, McMahon S, Zeugolis DI, Windebank A, Pandit A.  (2010) 'Spinal cord injury in vitro: modelling axon growth inhibition. '. Drug Discov Today, 15 (11-12):436-443 [Details]
(2009) 'Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord Without Differentiating into Neural Cells'
Rooney, GE,McMahon, SS,Ritter, T,Garcia, Y,Moran, C,Madigan, NN,Flugel, A,Dockery, P,O'Brien, T,Howard, L,Windebank, AJ,Barry, FP (2009) 'Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord Without Differentiating into Neural Cells'. Tissue Engineering Part A, 15 :3049-3059 [DOI] [ARAN Link] [Details]
(2009) 'Analysis of cellular environment of spinal cord lesion following transplantation of neural stem cells into injured rat spinal cord'
Hynes, J.,Bourke, E.,Deering, E. M.,Doherty, G.,Murray, A.,Dockery, P.,Doyle, K.,Gorman, A.,Barry, F. P.,McMahon, S. S. (2009) 'Analysis of cellular environment of spinal cord lesion following transplantation of neural stem cells into injured rat spinal cord'. Journal of Anatomy, 214 (55):793-793 [Details]
(2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'
McMahon SS, Albermann S, Rooney GE, Moran C, Hynes J, Garcia Y, Dockery P, O'Brien T, Windebank AJ, Barry FP (2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'. Journal Of Anatomy, 215 (3):267-279 [DOI] [Details]
(2009) 'Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds'
Madigan NN, McMahon S, O'Brien T, Yaszemski MJ, Windebank AJ. (2009) 'Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds'. Respiratory Medicine, 169 (2):183-199 [Details]
(2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'
Rooney, GE,Moran, C,McMahon, SS,Ritter, T,Maenz, M,Flugel, A,Dockery, P,O'Brien, T,Howard, L,Windebank, AJ,Barry, FP (2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'. Tissue Engineering Part A, 14 :681-690 [DOI] [Details]
(2007) 'Developmental potential of radial glia investigated by transplantation into the developing rat ventricular system in utero'
McMahon, SS,McDermott, KW (2007) 'Developmental potential of radial glia investigated by transplantation into the developing rat ventricular system in utero'. Experimental Neurology, 203 :128-136 [DOI] [Details]
(2006) 'A comparison of cell transplantation and retroviral gene transfection as tools to study lineage and differentiation in the rat spinal cord'
McMahon, SS,McDermott, KW (2006) 'A comparison of cell transplantation and retroviral gene transfection as tools to study lineage and differentiation in the rat spinal cord'. Journal Of Neuroscience Methods, 152 :243-249 [DOI] [Details]
(2005) 'Role of radial glia in cytogenesis, patterning and boundary formation in the developing rat spinal cord'
McDermott K.W., Barry D.S. & McMahon S.S. (2005) 'Role of radial glia in cytogenesis, patterning and boundary formation in the developing rat spinal cord'. JOURNAL OF ANATOMY, 207 :241-250 [Details]
(2003) 'Estimation of nuclear volume as an indicator of maturation of glial precursor cells in the developing rat spinal cord: a stereological approach'
McMahon SS, Dockery P, McDermott KW (2003) 'Estimation of nuclear volume as an indicator of maturation of glial precursor cells in the developing rat spinal cord: a stereological approach'. Journal Of Anatomy, 203 (3):339-344 [Details]
(2002) 'Morphology and differentiation of radial glia in the developing rat spinal cord'
McMahon, SS,McDermott, KW (2002) 'Morphology and differentiation of radial glia in the developing rat spinal cord'. J Comp Neurol, 454 :263-271 [DOI] [Details]
(2001) 'Proliferation and migration of glial precursor cells in the developing rat spinal cord'
McMahon, SS,McDermott, KW (2001) 'Proliferation and migration of glial precursor cells in the developing rat spinal cord'. Journal Of Neurocytology, 30 :821-828 [Details]

Book Chapters

  Year Publication
(2021) 'Lectin Histochemistry for Tissues and Cells, and Dual Lectin and Antibody Co-localization'
Siobhán S. McMahon and Michelle Kilcoyne (2021) 'Lectin Histochemistry for Tissues and Cells, and Dual Lectin and Antibody Co-localization' In: Part of the Methods in Molecular Biology book series. Humana Press: Springer protocols. [Details]

Conference Publications

  Year Publication
(2024) 21st congress of the international federation of associations of anatomists
Melissa A Carroll, Kirsten M Brown, Laura Y Whitburn, Peter J Vollbrecht, Amanda J Meyer, Claudia Krebs, Dara M Cannon, Doris George Yohannan, José Paulo Andrade, Eustathia Lela Giannaris, Mark Pickering, Matthew J Vilburn, Mónica López Hidalgo, Ronnie E Baticulon, Scott Border, Siobhan McMahon, Tom Flanagan, Valeria A Forlizzi, Yolanda Salinas-Alvarez, Mikaela L Stiver. (2024) The Global Neuroanatomy Network (GNN): an Academic Repository for Educators Worldwide 21st congress of the international federation of associations of anatomists [Details]
(2024) Anatomy Connected 2024
Mikaela L Stiver, Dara M Cannon, Amanda J Meyer, Claudia Krebs, Doris George Yohannan, José Paulo Andrade, Kirsten M Brown, Laura Y Whitburn, Eustathia Lela Giannaris, Mark Pickering, Matthew J Vilburn, Mónica López Hidalgo, Peter J Vollbrecht, Ronnie E Baticulon, Roxanne Larsen, Scott Border, Siobhan McMahon, Tom Flanagan, Valeria A Forlizzi, Yolanda Salinas-Alvarez, Melissa A Carroll. (2024) Neuroanatomy educators, meet your global community: inception and implementation of the Global Neuroanatomy Network Anatomy Connected 2024 [Details]
(2023) Galway Neuroscience Centre research day, University of Galway
Ciara Shortiss, Rachel Chapla, Joanne O¿Dwyer, Tapas Mitra, Garry P. Duffy, Nicolas Madigan, Anthony Windebank, Siobhan S. McMahon, Linda Howard (2023) Lentiviral Vectors in combination with Biomaterial Scaffolds for Spinal Cord Injury Regeneration Galway Neuroscience Centre research day, University of Galway [Details]
(2023) Atlantic Corridor Research Conference, University of Galway
Éadaoin Halligan , Ciara Shortiss, Michelle Kilcoyne , Peter Dockery , Linda Howard and Siobhan McMahon (2023) Modulating Proteoglycan Synthesis for Promotion of Neurite Outgrowth Atlantic Corridor Research Conference, University of Galway [Details]
(2023) School of Medicine Undergraduate Research Day, University of Galway
Éadaoin Halligan, Ciara Shortiss , Michelle Kilcoyne , Peter Dockery , Linda Howard and Siobhan McMahon (2023) Modulating Proteoglycan Synthesis for Promotion of Neurite Outgrowth School of Medicine Undergraduate Research Day, University of Galway [Details]
(2023) Neuroscience Ireland conference, RCSI, Dublin
Ciara Shortiss, Rachel Chapla, Joanne O¿Dwyer, Tapas Mitra, Garry P. Duffy, Nicolas Madigan, Anthony Windebank, Siobhan S. McMahon, Linda Howard (2023) Lentiviral Vectors in combination with Biomaterial Scaffolds for Spinal Cord Injury Regeneration Neuroscience Ireland conference, RCSI, Dublin [Details]
(2023) Central Nervous System Injury and Repair Gordon Research Conference, Renaissance Tuscany Il Ciocco in Lucca, Italy
Sorour Nemati, Michelle Kilcoyne, Dimitrios Zeugolis, Siobhan McMahon (2023) Macromolecular crowding enhances the extracellular matrix deposition of astrocytes Central Nervous System Injury and Repair Gordon Research Conference, Renaissance Tuscany Il Ciocco in Lucca, Italy [Details]
(2023) International Symposium for Neural Regeneration, Stevenson WA
Ciara Shortiss, Michelle Kilcoyne, Nicolas Madigan, Anthony Windebank, Siobhan M McMahon and Linda Howard (2023) Modulating Proteoglycan Synthesis for Spinal Cord Injury Regeneration International Symposium for Neural Regeneration, Stevenson WA [Details]
(2023) Anatomical Society meeting, Nottingham, UK
Scott Border, Siobhan McMahon, Dara M Cannon, Tom Flanagan, Mark Pickering, Melissa A Carroll, Mikaela L Stiver (2023) The Global Neuroanatomy Network: an online community of practice for sharing knowledge and experience in neuroanatomy education Anatomical Society meeting, Nottingham, UK [Details]
(2022) Galway Neuroscience Centre research day
Sorour Nemati, Michelle Kilcoyne, Dimitrios Zeugolis, Siobhan McMahon (2022) The effect of macromolecular crowders on deposition of extracellular matrix in astrocyte cultures Galway Neuroscience Centre research day [Details]
(2022) Anatomical Society Meeting, University College Dublin
. Ciara Shortiss, Siobhan McMahon, Linda Howard (2022) Modulating proteoglycan synthesis for spinal cord injury regeneration Anatomical Society Meeting, University College Dublin [Details]
(2022) Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference, Krakow, Poland
Sorour Nemati, Michelle Kilcoyne, Dimitrios Zeugolis, Siobhan McMahon. (2022) The effect of macromolecular crowders on deposition of extracellular matrix in astrocyte cultures Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference, Krakow, Poland [Details]
(2021) Microscopy Society of Ireland- Scottish Microscopy joint conference, Galway
Ciara Shortiss, Linda Howard, Siobhan McMahon (2021) Investigation into the morphological response of spinal cord cells in mixed glial culture to inflammation Microscopy Society of Ireland- Scottish Microscopy joint conference, Galway [Details]
(2021) Microscopy Society of Ireland- Scottish Microscopy joint conference, Galway
Sorour Nemati, Michelle Kilcoyne, Dimitrios Zeugolis, Siobhan McMahon (2021) Investigation the Effect of Macromolecular Crowders on Astrocytes Behavior Microscopy Society of Ireland- Scottish Microscopy joint conference, Galway [Details]
(2021) XV European Meeting on Glial Cells in Health and Disease.virtual meeting
Ciara Shortiss, Linda Howard and Siobhan S. McMahon (2021) Viability of rat organotypic spinal cord slices from animals at different ages and sexes alone and when subjected to in vitro injury XV European Meeting on Glial Cells in Health and Disease.virtual meeting [Details]
(2021) Galway Neuroscience Centre research day, NUI Galway
Ciara Shortiss, Siobhan S. McMahon and Linda Howard (2021) Modulating Proteoglycan synthesis for Spinal Cord Injury regeneration Galway Neuroscience Centre research day, NUI Galway [Details]
(2019) Gordon Research Conference: Central Nervous System Injury and Repair: From Molecules to Function. Waterville Valley, NH, US
Vaibhav Patil, Carla Winter, Michelle Kilcoyne, Siobhan McMahon, Abhay Pandit (2019) Development of a mixed glial model to study inflammation and associated glycosylation alterations in spinal cord injury Gordon Research Conference: Central Nervous System Injury and Repair: From Molecules to Function. Waterville Valley, NH, US [Details]
(2019) British Neuroscience Association Festival of Neuroscience, Dublin
Vaibhav Patil, Ms Carla Winter,, Dr Siobhan McMahon, Dr Michelle Kilcoyne, Prof. Abhay Pandit (2019) Cytokine-induced inflamed mixed glial in-vitro model to study inflammatory and glycan responses associated with spinal cord injury British Neuroscience Association Festival of Neuroscience, Dublin [Details]
(2018) EMBO Conference, Malta
Aniket Kshirsagar, Rachel Ronan, Ana Lucia Rebelo, Gerhard Schlosser, Siobhan McMahon, Abhay Pandit. (2018) Molecular Mechanisms of Spinal Cord Regeneration in Xenopus EMBO Conference, Malta [Details]
(2018) Gordon Research Conference, Barcelona
Rachel Ronan, Aniket Kshirsagar, Michelle Kilcoyne, Gerhard Schlosser, Róisín O¿Flaherty, Radka Saldova, Abhay Pandit, Siobhan McMahon. (2018) Glycan and glial regulation of the regenerative process following spinal cord injury, and the influence of biomaterial treatment Gordon Research Conference, Barcelona [Details]
(2018) Gordon research conference, Barcelona
Aniket Kshirsagar, Rachel Ronan, Ana Lucia Rebelo, Gerhard Schlosser, Abhay Pandit, Siobhan McMahon. (2018) Spinal cord regeneration in Xenopus laevis. Gordon research conference: The Role of Innate Immunity Gordon research conference, Barcelona [Details]
(2018) FENS forum of Neuroscience, Berlin
Vaibhav Patil, Carla Winter, Michelle Kilcoyne, Siobhan McMahon, Abhay Pandit (2018) Cytokine-induced inflamed mix glial in-vitro model to study inflammatory and glycan response associated with spinal cord injury FENS forum of Neuroscience, Berlin [Details]
(2017) Matrix Biology Ireland, Dublin
R Ronan, A Kshirsagar, AL Rebelo, M Kilcoyne, G Schlosser, A Pandit, S McMahon (2017) Glycosylation changes in the injured and regenerating spinal cord of Xenopus laevis Matrix Biology Ireland, Dublin [Details]
(2017) Neuroscience Ireland, Galway
R Ronan, A Kshirsagar, AL Rebelo, M Kilcoyne, G Schlosser, A Pandit, S McMahon (2017) Cellular and glycomic facilitators of regeneration in a Xenopus laevis model of spinal cord injury Neuroscience Ireland, Galway [Details]
(2017) Neuroscience Ireland conference, Galway
Vaibhav Patil Carla Winter, Elke Rink, Siobhan McMahon, Michelle Kilcoyne, Abhay Pandit (2017) Cytokine-induced inflamed mix glial in vitro model to study inflammation and glycobiology associated with spinal cord injury Neuroscience Ireland conference, Galway [Details]
(2017) Neuroscience Ireland conference, Galway
Azim Patar, Peter Dockery, Linda Howard and Siobhan McMahon (2017) The use of Neurotrophin-3 and short hairpin NG2 knockdown lentiviruses to promote neurite outgrowth in vitro Neuroscience Ireland conference, Galway [Details]
(2017) EUROCARB, Barcelona, Spain
R Ronan, A Kshirsagar, M Kilcoyne, R O¿Flaherty, R Saldova, G Schlosser, A Pandit, S McMahon (2017) Glycobiology of spinal cord injury and repair EUROCARB, Barcelona, Spain [Details]
(2017) Anatomical Society conference, Galway
Azim Patar, Emma Geraghty, Peter Dockery, Linda Howard and Siobhan McMahon (2017) Chondroitinase ABC alters the microenvironment of ex vivo rat spinal cord injury Anatomical Society conference, Galway [Details]
(2016) Neuroscience Ireland Young Neuroscientists Meeting
Patil, V., McMahon, S. and Pandit, A. (2016) Primary Mix Glial Culture from Spinal Cord Inflamed by Pro-Inflammatory Cytokines is a Valid Model of Inflammation after Spinal Cord Injury Neuroscience Ireland Young Neuroscientists Meeting [Details]
(2016) Bioengineering in Ireland Conference
R Ronan, A Kshirsagar, AL Rebelo, G Schlosser, S McMahon, A Pandit (2016) Studying regeneration in tadpole xenopus laevis for improved biomaterial therapy design for the injured spinal cord Bioengineering in Ireland Conference [Details]
(2015) Advanced Functional Polymers for Medicine 2015, Galway, Ireland
Rachel Ronan, Honorata Kraskiewicz, Bridget Breen, Timothy Sargeant, Abhay Pandit, Siobhan McMahon (2015) A Collagen-based Multimodal Delivery System Provides Therapeutic Factors and Physical Support for Treatment of Spinal Cord Injury in the Rat Advanced Functional Polymers for Medicine 2015, Galway, Ireland [Details]
(2015) Microscopy Society of Ireland Symposium 2015, Limerick, Ireland
Rachel Ronan, Aniket Kshirsagar, Michelle Kilcoyne, Gerhard Schlosser, Abhay Pandit, Siobhan McMahon (2015) Glycobiology of the Spinal Cord in Tadpole Xenopus Laevis Microscopy Society of Ireland Symposium 2015, Limerick, Ireland [Details]
(2015) 3rd international meeting on spinal cord repair - ISCORE, Barcelona, Spain
Siobhan S. McMahon, Azim Patar, Kerry Thompson, Frank Barry, Lokesh Joshi, Michelle Kilcoyne (2015) Differential glycosylation expression in injured rat spinal cord treated with Cyclosporin A 3rd international meeting on spinal cord repair - ISCORE, Barcelona, Spain [Details]
(2015) NUIG Galway Neuroscience Centre research day, NUI Galway, Ireland
Vaibhav Patil, Elke Rink, Siobhan McMahon , Abhay Pandit (2015) Generation of rat primary spinal cord glial culture to study inflammation after spinal cord injury NUIG Galway Neuroscience Centre research day, NUI Galway, Ireland [Details]
(2015) Neuroscience Ireland Conference 2015, Dublin, Ireland
Aniket Kshirsagar, Rachel Ronan, Ana Lucia Rebelo, Elke Rink, Gerhard Schlosser, Siobhan McMahon and Abhay Pandit (2015) Development of Non-mammalian system Xenopus laevis to study spinal cord regeneration Neuroscience Ireland Conference 2015, Dublin, Ireland [Details]
(2014) European Society for Biomaterials Conference, Liverpool, UK
Rachel Ronan, Honorata Kraskiewicz, Bridget Breen, Timothy Sargeant. Abhay Pandit, Siobhan McMahon (2014) A Collagen-Based Multimodal Delivery System Provides Therapeutic Factors as well as Physical Support for Treatment of Spinal Cord Injury in the Rat European Society for Biomaterials Conference, Liverpool, UK [Details]
(2014) Network for European CNS Transplantation & Restoration, Galway, Ireland
Rachel Ronan, Honorata Kraskiewicz, Bridget Breen, Timothy Sargeant, Abhay Pandit, Siobhan McMahon (2014) A Collagen-Based Multimodal Delivery System Provides Therapeutic Factors as well as Physical Support for Treatment of Spinal Cord Injury in the Rat Network for European CNS Transplantation & Restoration, Galway, Ireland [Details]
(2014) Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting, Genoa, Italy
Honorata Kraskiewicz, Bridget Breen, Timothy Sargeant, Siobhan McMahon and Abhay Pandit (2014) A Platform Delivery Technology for Spinal Cord Regeneration Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting, Genoa, Italy [Details]
(2013) Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin
Niall Bergin, Nicolas Madigan, Bridget Breen, Peter Owens, Timothy O’Brien, Anthony Windebank, Siobhan McMahon (2013) Expression of CD68 positive macrophages in mesenchymal stem cell and schwann cell loaded scaffolds in a transection model of spinal cord injury Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin [Details]
(2013) Microscopy Society of Ireland, NUI Galway
Niall Bergin, Nicolas Madigan, Kerry Thompson, Timothy O’Brien, Anthony Windebank, Siobhan McMahon (2013) Analysis of proinflammatory and anti-inflammatory macrophages within cell loaded scaffolds in a transection model of spinal cord injury Microscopy Society of Ireland, NUI Galway [Details]
(2013) Cell Based Therapies in CNS Pathology Symposium, Hasselt University, Belgium
Siobhan McMahon (2013) Neural stem cells and mesenchymal stem cells in treatment of spinal cord injury Cell Based Therapies in CNS Pathology Symposium, Hasselt University, Belgium [Details]
(2013) Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin
Siobhan McMahon, Nicolas Madigan, Niall Bergin, Bridget Breen, Peter Owens, Timothy O’Brien, Anthony Windebank (2013) Analysis of axonal regeneration and inflammation within schwann cell and mesenchymal stem cell loaded polymer scaffolds in the transected rat spinal cord Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin [Details]
(2012) RAMI Biomedical Sciences Section Annual Meeting
E. Keane, N.N. Madigan, M. Canney, K. Thompson, T. O’Brien, A.J. Windebank, S.S. McMahon (2012) Apoptosis in cell-loaded scaffolds in a transection model of rat spinal cord injury RAMI Biomedical Sciences Section Annual Meeting [Details]
(2012) BNA conference on Bioengineering and Neuroal remodeling
E. Keane, N.N. Madigan, M. Canney, K. Thompson, T. O’Brien, A.J. Windebank, S.S. McMahon. (2012) Apoptosis in cell-loaded scaffolds in a transection model of rat spinal cord injury BNA conference on Bioengineering and Neuroal remodeling [Details]
(2012) Society for Neuroscience Conference
Honorata kraśkiewicz, Bridget Breen, Siobhan McMahon, Abhay Pandit (2012) The Development of a Growth Factor Delivery Platform Technology for Neurotrophins Society for Neuroscience Conference [Details]
(2012) Neuroscience Ireland Conference, RCSI, Dublin
Catherine Stacey, Bridget Breen, Kerry Thompson, Siobhan McMahon (2012) Effect of Chondroitinase ABC on microenvironment of organotypic injured spinal cord slice cultures Neuroscience Ireland Conference, RCSI, Dublin [Details]
(2011) 10th European Meeting on Glial Cells in Health and Disease
M. Abu-Rub, Michelle Naughton, Honorata Kraskiewicz, Benjamin Newland, Nicolas Madigan, Siobhan McMahon, Wenxin Wang, Anthony Windebank, Abhay Pandit. (2011) Non-viral gene knockdown of glial scar glycosaminoglycan synthesis 10th European Meeting on Glial Cells in Health and Disease [Details]
(2011) V EUROPEAN CHAPTER OF THE TISSUE ENGINEERING AND REGENERATIVE MEDICINE INTERNATIONAL SOCIETY (TERMIS)
M. Abu-Rub, B Newland, M Naughton, S McMahon, W Wang, A Windebank, A Pandit (2011) Scaffold mediated non-viral gene knockdown of glial scar glycosaminoglycan synthesis V EUROPEAN CHAPTER OF THE TISSUE ENGINEERING AND REGENERATIVE MEDICINE INTERNATIONAL SOCIETY (TERMIS) [Details]
(2010) Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting
N. Madigan, G. Rooney, A. Knight, B. Chen, L. Gross, M. Dadsetan, J. Nesbitt, M. Yaszemski, S. McMahon, T. O’Brien, A. Windebank. (2010) Axonal regeneration supported by Schwann cells and Mesenchymal Stem Cells through polymer scaffolds in the transected rat spinal cord Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting [Details]
(2010) Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting
Mohammad Abu-Rub, Andrew Knight, Siobhan. McMahon, Dimitrios Zeugolis, Anthony Windebank and Abhay Pandit (2010) Aligned Collagen Matrices Direct Neuronal Growth and Protect Against Inhibitory Myelin Components Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting [Details]
(2010) Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting
E. Donnelly, N. Madigan, G. Rooney, P. Strappe, A. Windebank, T. O’Brien, S. McMahon (2010) Lentiviral vector treatment of the inhibitory spinal cord injury environment in vitro and in vivo Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting [Details]
(2010) 23rd European Conference on Biomaterials
M. Abu-Rub, A. Knight, D. Zeugolis, S. McMahon A. Windebank and A. Pandit. (2010) Aligned Collagen Matrices Direct Neuronal Growth and Protect Against Inhibitory Myelin Components 23rd European Conference on Biomaterials [Details]
(2010) 13th Annual ASGCT Meeting
E. Donnelly, S. McMahon, P. Dockery, J. Fraher, P. Strappe, N. Madigan, L. McGinley, T. Windebank, T. O’Brien.. (2010) Modification of the inhibitory environment of spinal cord injury by lentiviral vector containing NT-3 and shRNA for NG2 13th Annual ASGCT Meeting [Details]
(2010) Neuroscience Ireland Meeting, University College Dublin
L. Kinnavane, E. Donnelly, P. Strappe, P. Dockery, J. Fraher, T. Windebank, T. O’Brien, S. McMahon. (2010) Axonal growth in the contused rat spinal cord: Promotion by neurotrophin-3 and knockdown of NG2 Neuroscience Ireland Meeting, University College Dublin [Details]
(2010) Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting
Michelle Kilcoyne, Ciara Bradley , Lokesh Joshi , Frank Barry and Siobhan McMahon (2010) Analysis of surface glycosylation and lectin differentials in spinal cord injury Tissue Engineering and Regenerative Medicine International Society-EU Chapter Meeting [Details]
(2010) Neuroscience Ireland Meeting, University College Dublin
D. Dooley, T. Windebank, F. Barry, S. McMahon. (2010) Response of astrocytes to Cyclosporin-A and neural stem cell treatment in contused rat spinal cord Neuroscience Ireland Meeting, University College Dublin [Details]
(2009) 6th Australasian Gene Therapy Society Meeting, Sydney
Siobhan McMahon, Gemma Rooney, Eleanor Donnelly, Timothy O’Brien, John Fraher, Anthony Windebank, Peter Dockery, David Hampton, Padraig Strappe. (2009) An astrocyte-dorsal root ganglion co-culture model to assess neurite outgrowth from lentiviral vector expressed Neurotrophin-3 6th Australasian Gene Therapy Society Meeting, Sydney [Details]
(2009) 2nd TERMIS World Congress, Seoul, Republic of Korea
Mohammad T. Abu-Rub, Siobhan McMahon, Anthony Windebank, Abhay Pandit and Dimitrios Zeugolis. (2009) Self Assembled Nanofibrous Collagen Hydrogels Direct Axonal Regrowth and Promote Migration with Substrate Bound Cues 2nd TERMIS World Congress, Seoul, Republic of Korea [Details]
(2009) SFN Meeting, Chicago
N. N. Madigan, G. Rooney, A. Knight, B. Chen, L. Gross, M. Dadstetan, J. Nesbitt, M. Yaszemski, S. McMahon, A. Windebank. (2009) Axonal regeneration supported by neurotrophic Schwann cells and mesenchymal stem cells through polymer scaffolds in the transected rat spinal cord SFN Meeting, Chicago [Details]
(2009) ESGCT meeting, Hannover, Germany
Eleanor Donnelly, Peter Dockery, John Fraher, Padraig Strappe, Daniel O’Toole, Nicolas Madigan, Lisa McGinley, Anthony Windebank, Timothy O’Brien, Siobhan McMahon. (2009) Lentiviral vector treatment of the inhibitory spinal cord injury environment in vitro and in vivo ESGCT meeting, Hannover, Germany [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
Jacqueline Hynes, Elaine Bourke, Eoin McCarthy Deering, Graham Doherty, Andrea Murray, Peter Dockery, Karen Doyle, Adrienne Gorman, Timothy Allsopp; Frank P. Barry, Siobhan S. McMahon. (2008) Neural stem cells reduce apoptosis following transplantation into injured rat spinal cord Neuroscience Ireland Meeting, NUI Galway [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
Siobhan S. McMahon, Silke Albermann, Gemma E. Rooney, Timothy O’Brien, Yolanda Garcia, Peter Dockery, Anthony J. Windebank, Timothy E. Allsopp, Frank P. Barry. (2008) Analysis of neural stem cells following transplantation into injured rat spinal cord Neuroscience Ireland Meeting, NUI Galway [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
N. Madigan, G. Rooney, T. Ritter, F. Barry, A. Windebank, T. O’Brien, S. McMahon (2008) Regeneration of injured spinal cord neurons through implantable polymer bridges using a combined approach of neurotrophic support and glial scar inhibition Neuroscience Ireland Meeting, NUI Galway [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
S.McMahon, N Nikolskaya, S. Ní Choileán, N. Hennessy, Y Rochev. (2008) Thermosensitive Hydrogel For Prolonged Lentivirus Delivery Neuroscience Ireland Meeting, NUI Galway [Details]
(2008) ESGCT meeting, Brugge, Belgium
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O’Toole, Lisa McGinley, Timothy O’Brien (2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord ESGCT meeting, Brugge, Belgium [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
Claire O’Leary, Michelle Kilcoyne, Lokesh Joshi, Peter Dockery, Siobhan McMahon. (2008) Analysis Of Neuron Cell Surface Glycosylation Differentials In A Chondroitin Sulphate Proteoglycan Inhibitory Environment Neuroscience Ireland Meeting, NUI Galway [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
Eleanor Donnelly, Lisa McGinley, Peter Dockery, John Fraher, Padraig Strappe, Daniel O’Toole, Nicolas Madigan, Gemma Rooney, Timothy O’Brien, Siobhan McMahon. (2008) Silencing Ng2 Inhibitory Factor And Its Effect On Dorsal Root Ganglia Neurite Outgrowth Neuroscience Ireland Meeting, NUI Galway [Details]

Professional Associations

  Association Function From / To
Anatomical Society Member /
European Neurotrauma Organisation Member /
American Association for Anatomy Member /
European Organ on a Chip Society Member /
Neuroscience Ireland Member /
Federation of European Neuroscience Societies Member /

Committees

  Committee Function From / To
School of Medicine EDI committee committee member 03-JAN-22 /
College of Science and Engineering GY301 Science Programme Board committee member 06-SEP-21 /
Galway Neuroscience Centre Committee Deputy Director 06-NOV-06 /

Employment

  Employer Position From / To
University of Galway Lecturer in Department of Anatomy /
University of Galway Postdoctoral Research Fellow,Regenerative Medicine 10-OCT-05 / 03-NOV-06
University College Cork Postdoctoral Research Fellow, Dept of Anatomy 02-SEP-02 / 05-SEP-05
University College Cork Research Technician, Department of Anatomy 03-SEP-01 / 08-APR-02

Education

  Year Institution Qualification Subject
2017 University of Galway Postgraduate Diploma Academic Practice
2000 University College Cork PhD Neuroanatomy
1994 Maynooth University BSc Biology

Community Engagement

  Title Type From / To
Outreach Brain Awareness Week /
Outreach START Meet the Scientist /
Outreach Soapbox Science /
Outreach Reellife Science /

Other Activities

  Description

Global Neuroanatomy Network founding member

Expert member of national standard authority of Ireland (NSAI) and European committee for standardization (CEN) national member

Teaching Interests

Dr McMahon teaches human anatomy to undergraduate students in science, medicine, nursing and health science. 



Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2021 Vaibhav Patil PhD
2020 Rachel Ronan PhD Y
2020 Aniket Kshirsagar PhD
2018 Azim Patar PhD Y
2012 Nicolas Madigan PhD Y
2010 Eleanor Donnelly PhD Y

Current Postgraduate Students (Research)

  Student Degree Type Type
Sorour Nemati Doctorate - Structured Ph.D (Medicine) Supervisor
Ciara Shortiss Doctorate - Structured Ph.D (Medicine) Supervisor

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
semester 1 The central nervous system MD224 neuroanatomy (medical students)
semester 1 Biological science 1 NU1107 anatomy (nursing students)
semester 1 Biological science 2 NU2200 anatomy (nursing students)
semester 1 Functional anatomy and biomechanics PO203 lower limb anatomy (podiatry students)
semester 1 Health and safety systems AN225 human anatomy (science students)
semester 1 Neuroanatomy AN208 neuroanatomy (health science students)
semester 1 Neuroanatomy AN326 neuroanatomy (science students)
semester 2 Head and neck anatomy AN4107 anatomy (science students)
semester 2 Gross anatomy of the lower limb AN112 lower limb anatomy (podiatry students)
semester 2 Embryology and development AN223 systems development (science students)
semester 2 Research project AN444 lab project (science students)
semester 2 Biomed Seminars BM202 supervision of biomedical science student group project
semester 2 Introduction to medicine MD103 neuroanatomy (medical students)

Internal Collaborators

  Name Description of Collaboration
Dr Linda Howard
Professor Peter Dockery
Dr Yury Rochev
Professor Abhay Pandit
Dr Michelle Kilcoyne

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Professor Dimitrios Zeugolis University College Dublin IRELAND
Professor James Phillips University College London UNITED KINGDOM
Dr Nicolas Madigan Mayo Clinic U.S.A.
Professor Anthony Windebank Mayo Clinic U.S.A.