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Medicine

Prof John Kelly

B.Sc., Ph.D.

 
researcher
 

Biography

My current position is as a Personal Professor in the Department of Pharmacology and Therapeutics, University of Galway. I have spent over 40 years involved in pharmacological and toxicological research, 8 of which have been in industry.

Research Interests

My research has centred on preclinical animal models of depression, most particularly investigating the olfactory bulbectomized and whether this myriad of changes associated with this model can be attenuated by chronic treatment with antidepressants, both established and novel treatments. This research has demonstrated how valuable the integrated approach can be in ascertaining interactions between behavioural, physiological, neurochemical and immune changes. A similar approach has been taken with other animal models under my direction, such as the Forced Swim Test and lipopolysaccharide models. This research has resulted in over 100 peer-reviewed publications.

Peer Reviewed Journals

  Year Publication
(2022) 'Dual hit mouse model to examine the long-term effects of maternal immune activation and post-weaning social isolation on schizophrenia endophenotypes'
Desbonnet L, Konkoth A, Laighneach A, McKernan D, Holleran L, McDonald C, Morris DW, Donohoe G, Kelly J. (2022) 'Dual hit mouse model to examine the long-term effects of maternal immune activation and post-weaning social isolation on schizophrenia endophenotypes'. Behav Brain Res, [Details]
(2022) 'Childhood trauma, IL-6 and weaker suppression of the default mode network (DMN) during theory of mind (ToM) performance in schizophrenia'
King S, Mothersill D, Holleran L, Patlola S, McManus R, Kenyon M, McDonald C, Hallahan B, Corvin A, Morris DW, Kelly JP, McKernan D, Donohoe G. (2022) 'Childhood trauma, IL-6 and weaker suppression of the default mode network (DMN) during theory of mind (ToM) performance in schizophrenia'. Brain Behavior And Immunity, [Details]
(2022) 'Corpus Callosum Microstructural Tract Integrity Relates to Longer Emotion Recognition Reaction Time in People with Schizophrenia'
Burke T, Gleeson C, Holleran L, Mothersill D, Holland J, Costello L, Kane R, McKernan DP, Morris DW, Kelly JP, Corvin AP, Hallahan BP, McDonald C, Donohoe G. (2022) 'Corpus Callosum Microstructural Tract Integrity Relates to Longer Emotion Recognition Reaction Time in People with Schizophrenia'. Brain Sciences, [Details]
(2021) 'Mu-opioid receptor agonism differentially alters social behaviour and immediate early gene expression in male adolescent rats prenatally exposed to valproic acid versus controls'
Hughes EM, Calcagno P, Sanchez C, Smith K, Kelly JP, Finn DP, Roche M. (2021) 'Mu-opioid receptor agonism differentially alters social behaviour and immediate early gene expression in male adolescent rats prenatally exposed to valproic acid versus controls'. Brain Research Bulletin, [Details]
(2020) 'Childhood trauma, brain structure and emotion recognition in patients with schizophrenia and healthy participants'
Rokita KI, Holleran L, Dauvermann MR, Mothersill D, Holland J, Costello L, Kane R, McKernan D, Morris DW, Kelly JP, Corvin A, Hallahan B, McDonald C, Donohoe G. (2020) 'Childhood trauma, brain structure and emotion recognition in patients with schizophrenia and healthy participants'. Social Cognitive And Affective Neuroscience, [Details]
(2021) 'Hyporesponsivity to mu-opioid receptor agonism in the Wistar-Kyoto rat model of altered nociceptive responding associated with negative affective state'
Ferdousi MI, Calcagno P, Clarke M, Aggarwal S, Sanchez C, Smith KL, Eyerman DJ, Kelly JP, Roche M, Finn DP. (2021) 'Hyporesponsivity to mu-opioid receptor agonism in the Wistar-Kyoto rat model of altered nociceptive responding associated with negative affective state'. Mol Pain, [Details]
(2021) 'Meta-Analysis of Brain Gene Expression Data from Mouse Model Studies of Maternal Immune Activation Using Poly(I:C)'
Laighneach A, Desbonnet L, Kelly JP, Donohoe G, Morris DW. (2021) 'Meta-Analysis of Brain Gene Expression Data from Mouse Model Studies of Maternal Immune Activation Using Poly(I:C)'. Genes, [Details]
(2021) 'Mu-opioid receptor agonism differentially alters social behaviour and immediate early gene expression in male adolescent rats prenatally exposed to valproic acid versus controls'
Hughes EM, Calcagno P, Sanchez C, Smith K, Kelly JP, Finn DP, Roche M (2021) 'Mu-opioid receptor agonism differentially alters social behaviour and immediate early gene expression in male adolescent rats prenatally exposed to valproic acid versus controls'. Brain Research Bulletin, (174):260-267 [DOI] [Details]
(2021) 'Changes in Default-Mode Network Associated with Childhood Trauma in Schizophrenia'
Dauvermann MR, Mothersill D, Rokita KI, King S, Holleran L, Kane R, McKernan DP, Kelly JP, Morris DW, Corvin A, Hallahan B, McDonald C, Donohoe G (2021) 'Changes in Default-Mode Network Associated with Childhood Trauma in Schizophrenia'. Schizophrenia Bulletin, [DOI] [Details]
(2020) 'Kappa Opioid Receptor-mediated Modulation of Social Responding in Adolescent Rats and in Rats Prenatally Exposed to Valproic Acid'
Hughes EM;Thornton AM;Kerr DM;Smith K;Sanchez C;Kelly JP;Finn DP;Roche M; (2020) 'Kappa Opioid Receptor-mediated Modulation of Social Responding in Adolescent Rats and in Rats Prenatally Exposed to Valproic Acid'. Neuroscience, 444 [DOI] [Details]
(2020) 'Hyporesponsivity to mu-opioid receptor agonism in the Wistar-Kyoto rat model of altered nociceptive responding associated with negative affective state'
Ferdousi MI;Calcagno P;Clarke M;Aggarwal S;Sanchez C;Smith KL;Eyerman DJ;Kelly JP;Roche M;Finn DP; (2020) 'Hyporesponsivity to mu-opioid receptor agonism in the Wistar-Kyoto rat model of altered nociceptive responding associated with negative affective state'. Pain, [DOI] [ARAN Link] [Details]
(2020) 'Kappa Opioid Receptor-mediated Modulation of Social Responding in Adolescent Rats and in Rats Prenatally Exposed to Valproic Acid'
Hughes, EM,Thornton, AM,Kerr, DM,Smith, K,Sanchez, C,Kelly, JP,Finn, DP,Roche, M (2020) 'Kappa Opioid Receptor-mediated Modulation of Social Responding in Adolescent Rats and in Rats Prenatally Exposed to Valproic Acid'. Neuroscience, 444 :9-18 [DOI] [ARAN Link] [Details]
(2020) 'Childhood Trauma, Brain Structure and Emotion Recognition in Patients with Schizophrenia and Healthy Participants'
Rokita KI;Holleran L;Dauvermann MR;Mothersill D;Holland J;Costello L;Kane R;McKernan D;Morris DW;Kelly JP;Corvin A;Hallahan B;McDonald C;Donohoe G; (2020) 'Childhood Trauma, Brain Structure and Emotion Recognition in Patients with Schizophrenia and Healthy Participants'. Social Cognitive And Affective Neuroscience, [DOI] [Details]
(2020) 'Prenatal exposure to valproic acid reduces social responses and alters mRNA levels of opioid receptor and pre-pro-peptide in discrete brain regions of adolescent and adult male rats'
Hughes, EM,Calcagno, P,Clarke, M,Sanchez, C,Smith, K,Kelly, JP,Finn, DP,Roche, M (2020) 'Prenatal exposure to valproic acid reduces social responses and alters mRNA levels of opioid receptor and pre-pro-peptide in discrete brain regions of adolescent and adult male rats'. Brain Research, 1732 [DOI] [Details]
(2020) 'Interventions for the management of obesity in people with bipolar disorder'
TullyA, SmythS, ConwayY, GeddesJ, DevaneD, KellyJP, JordanF. (2020) 'Interventions for the management of obesity in people with bipolar disorder'. The Cochrane Database Of Systematic Reviews, [DOI] [Details]
(2020) 'Interventions for the management of obesity in people with bipolar disorder'
TullyA, SmythS, ConwayY, GeddesJ, DevaneD, KellyJP, JordanF. (2020) 'Interventions for the management of obesity in people with bipolar disorder'. The Cochrane Database Of Systematic Reviews, [DOI] [Details]
(2020) 'Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure'
Santos, AMD;Gorman, AM;Kelly, JP;Doyle, KM (2020) 'Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure'. Neuroscience Letters, 715 [DOI] [Details]
(2020) 'Prenatal exposure to valproic acid reduces social responses and alters mRNA levels of opioid receptor and pre-pro-peptide in discrete brain regions of adolescent and adult male rats'
Hughes EM;Calcagno P;Clarke M;Sanchez C;Smith K;Kelly JP;Finn DP;Roche M; (2020) 'Prenatal exposure to valproic acid reduces social responses and alters mRNA levels of opioid receptor and pre-pro-peptide in discrete brain regions of adolescent and adult male rats'. Brain Research, doi: 10.1016/j.brainres.2020.146675 [DOI] [ARAN Link] [Details]
(2015) 'Development and Characterization of a Novel, Anatomically Relevant Rat Model of Acute Postoperative Pain'
Bree D, Moriarty O, O'Mahony CM, Morris B, Bannerton K, Broom DC, Kelly JP, Roche M, Finn DP (2015) 'Development and Characterization of a Novel, Anatomically Relevant Rat Model of Acute Postoperative Pain'. Journal Of Pain, [Details]
(2020) 'Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure'
Moreira da Silva Santos A, Gorman AM, Kelly JP, Doyle KM (2020) 'Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure'. Neuroscience Letters, [ARAN Link] [Details]
(2019) 'Chronic administration of buprenorphine in combination with samidorphan produces sustained effects in olfactory bulbectomised rats and Wistar-Kyoto rats'
Burke, NN,Li, Y,Deaver, DR,Finn, DP,Roche, M,Eyerman, DJ,Sanchez, C,Kelly, JP (2019) 'Chronic administration of buprenorphine in combination with samidorphan produces sustained effects in olfactory bulbectomised rats and Wistar-Kyoto rats'. Journal Of Psychopharmacology, [DOI] [ARAN Link] [Details]
(1994) 'THE EFFECT OF STRESSFUL BEHAVIORAL EXPOSURE ON ENDOCRINE AND IMMUNE PARAMETERS IN THE RAT'
SONG, C;KELLY, JP;LEONARD, BE (1994) 'THE EFFECT OF STRESSFUL BEHAVIORAL EXPOSURE ON ENDOCRINE AND IMMUNE PARAMETERS IN THE RAT'. Stress Medicine, 10 :239-245 [Details]
(1994) 'DOSE-DEPENDENT BEHAVIORAL-EFFECTS OF PHENCYCLIDINE (PCP)'
NSIMBA, SED;KELLY, JP;LEONARD, BE (1994) 'DOSE-DEPENDENT BEHAVIORAL-EFFECTS OF PHENCYCLIDINE (PCP)'. Medical Science Research, 22 :207-209 [Details]
(1994) 'THE EFFECT OF TIANEPTINE AND SERTRALINE IN 3 ANIMAL-MODELS OF DEPRESSION'
KELLY, JP;LEONARD, BE (1994) 'THE EFFECT OF TIANEPTINE AND SERTRALINE IN 3 ANIMAL-MODELS OF DEPRESSION'. Neuropharmacology, 33 :1011-1016 [Details]
(1994) 'EFFECTS OF ACUTE PHENCYCLIDINE (PCP) ON DIFFERENT ROUTES OF ADMINISTRATION ON BEHAVIORAL PARAMETERS IN RATS'
NSIMBA, SED;KELLY, JP;LEONARD, BE (1994) 'EFFECTS OF ACUTE PHENCYCLIDINE (PCP) ON DIFFERENT ROUTES OF ADMINISTRATION ON BEHAVIORAL PARAMETERS IN RATS'. Medical Science Research, 22 :399-401 [Details]
(1994) 'ALTERATIONS IN IMMUNE AND ENDOCRINE PARAMETERS FOLLOWING OLFACTORY BULBECTOMY'
SONG, C;KELLY, JP;LEONARD, BE (1994) 'ALTERATIONS IN IMMUNE AND ENDOCRINE PARAMETERS FOLLOWING OLFACTORY BULBECTOMY'. Medical Science Research, 22 :593-595 [Details]
(1995) 'SOME BEHAVIORAL-EFFECTS OF METHIOTHEPIN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
MCNAMARA, MG;KELLY, JP;LEONARD, BE (1995) 'SOME BEHAVIORAL-EFFECTS OF METHIOTHEPIN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :583-585 [Details]
(1995) 'EFFECTS OF OLFACTORY BULBECTOMY AND CHRONIC AMITRIPTYLINE TREATMENT ON PHENCYCLIDINE (PCP)-INDUCED HYPERACTIVITY'
REDMOND, AM;KELLY, JP;LEONARD, BE (1995) 'EFFECTS OF OLFACTORY BULBECTOMY AND CHRONIC AMITRIPTYLINE TREATMENT ON PHENCYCLIDINE (PCP)-INDUCED HYPERACTIVITY'. Medical Science Research, 23 :351-352 [Details]
(1995) 'THE EFFECT OF ACUTE MDMA ADMINISTRATION ON BODY-TEMPERATURE, SERUM CORTICOSTERONE AND NEUROTRANSMITTER CONCENTRATIONS IN MALE AND FEMALE RATS'
MCNAMARA, MG;KELLY, JP;LEONARD, BE (1995) 'THE EFFECT OF ACUTE MDMA ADMINISTRATION ON BODY-TEMPERATURE, SERUM CORTICOSTERONE AND NEUROTRANSMITTER CONCENTRATIONS IN MALE AND FEMALE RATS'. Human Psychopharmacology-Clinical And Experimental, 10 :373-383 [Details]
(1995) 'The influence of route of administration on the diabetogenic effects of streptozotocin in the rat'
MacSweeney, CP;Kelly, JP;Leonard, BE (1995) 'The influence of route of administration on the diabetogenic effects of streptozotocin in the rat'. Medical Science Research, 23 :811-812 [Details]
(1995) 'SOME BEHAVIORAL AND NEUROCHEMICAL ASPECTS OF SUBACUTE (+/-)3,4-METHYLENEDIOXYMETHAMPHETAMINE ADMINISTRATION IN RATS'
MCNAMARA, MG;KELLY, JP;LEONARD, BE (1995) 'SOME BEHAVIORAL AND NEUROCHEMICAL ASPECTS OF SUBACUTE (+/-)3,4-METHYLENEDIOXYMETHAMPHETAMINE ADMINISTRATION IN RATS'. Pharmacology Biochemistry And Behavior, 52 :479-484 [Details]
(1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT TREATMENT FOLLOWING ACUTE ADMINISTRATION OF THE NEUROTOXIN TRIMETHYLTIN IN THE RAT'
REDROBE, JP;KELLY, JP;CHAMBERS, PL;LEONARD, BE (1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT TREATMENT FOLLOWING ACUTE ADMINISTRATION OF THE NEUROTOXIN TRIMETHYLTIN IN THE RAT'. Medical Science Research, 23 :407-408 [Details]
(1995) 'THE BEHAVIORAL-EFFECTS OF MILNACIPRAN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
REDMOND, AM;KELLY, JP;LEONARD, BE (1995) 'THE BEHAVIORAL-EFFECTS OF MILNACIPRAN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :533-534 [Details]
(1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT ADMINISTRATION ON THE CONDITIONED TASTE-AVERSION TO 8-OHDPAT IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
REDMOND, AM;KELLY, JP;LEONARD, BE (1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT ADMINISTRATION ON THE CONDITIONED TASTE-AVERSION TO 8-OHDPAT IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :487-488 [Details]
(1995) 'An investigation of the hyperactive response in the olfactory bulbectomised rat model of depression'
Kelly, JP;Leonard, BE (1995) 'An investigation of the hyperactive response in the olfactory bulbectomised rat model of depression'. Medical Science Research, 23 :837-838 [Details]
(1995) 'EFFECT OF ACUTE ADMINISTRATION OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE (MDMA) ON TEMPERATURE AND LOCOMOTOR-ACTIVITY IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
MCGRATH, C;KELLY, JP;MCHUGH, MF;LEONARD, BE (1995) 'EFFECT OF ACUTE ADMINISTRATION OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE (MDMA) ON TEMPERATURE AND LOCOMOTOR-ACTIVITY IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :199-201 [Details]
(1996) 'Does the serenic eltoprazine have antidepressant potential? - An investigation in three rodent paradigms'
Cryan, JF;Redmond, AM;Kelly, JP;Leonard, BE (1996) 'Does the serenic eltoprazine have antidepressant potential? - An investigation in three rodent paradigms'. Medical Science Research, 24 :719-720 [Details]
(1996) 'Behavioural effects of chronic glycine in the olfactory bulbectomised rat in the 'open field' test and on phencyclidine (PCP)-induced hyperactivity'
Redmond, AM;Kelly, JP;Leonard, BE (1996) 'Behavioural effects of chronic glycine in the olfactory bulbectomised rat in the 'open field' test and on phencyclidine (PCP)-induced hyperactivity'. Medical Science Research, 24 :55-56 [Details]
(1996) 'Effects of chronic desipramine on waiting behaviour for a food reward in olfactory bulbectomized rats'
Kelly, JP;Leonard, BE (1996) 'Effects of chronic desipramine on waiting behaviour for a food reward in olfactory bulbectomized rats'. Journal Of Psychopharmacology, 10 :153-156 [Details]
(1996) 'Some behavioural and neurochemical effects of ipsapirone in two rodent models of depression'
McNamara, MG;Kelly, JP;Leonard, BE (1996) 'Some behavioural and neurochemical effects of ipsapirone in two rodent models of depression'. Journal Of Psychopharmacology, 10 :126-133 [Details]
(1996) 'The plasma glucose profile of individual rats in response to a single subcutaneous injection of streptozotocin'
MacSweeney, CP;McGarvey, C;Kelly, JP;Leonard, BE (1996) 'The plasma glucose profile of individual rats in response to a single subcutaneous injection of streptozotocin'. Medical Science Research, 24 :13-14 [Details]
(1996) 'Home cage and open-field locomotor activity responses in singly housed olfactory bulbectomised rats'
Kelly, JP;Norman, TR;OHalloran, A;Leonard, BE (1996) 'Home cage and open-field locomotor activity responses in singly housed olfactory bulbectomised rats'. Medical Science Research, 24 :335-337 [Details]
(1996) 'The characterization of oxotremorine-induced hypothermic response in the rat'
Ryan, PM;Kelly, JP;Chambers, PL;Leonard, BE (1996) 'The characterization of oxotremorine-induced hypothermic response in the rat'. Pharmacology & Toxicology, 79 :238-240 [Details]
(1997) 'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat'
Cryan, JF;Redmond, AM;Kelly, JP;Leonard, BE (1997) 'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat'. European Neuropsychopharmacology, 7 :109-114 [Details]
(1997) 'Effect of acute desipramine treatment on immunological parameters in the rat'
Connor, TJ;Kelly, JP;Leonard, BE (1997) 'Effect of acute desipramine treatment on immunological parameters in the rat'. Medical Science Research, 25 :209-211 [Details]
(1997) 'An appraisal of the pharmacological and toxicological effects of a single oral administration of 3,4-methylenedioxymethamphetamine (MDMA) in the rat'
DeSouza, I;Kelly, JP;Harkin, AJ;Leonard, BE (1997) 'An appraisal of the pharmacological and toxicological effects of a single oral administration of 3,4-methylenedioxymethamphetamine (MDMA) in the rat'. Pharmacology & Toxicology, 80 :207-210 [Details]
(1997) 'Effect of phencyclidine and apomorphine administration in the olfactory bulbectomised rat'
McGrath, C;Kelly, JP;McHugh, MF;Leonard, BE (1997) 'Effect of phencyclidine and apomorphine administration in the olfactory bulbectomised rat'. Medical Science Research, 25 :829-831 [Details]
(1997) 'Forced swim test-induced neurochemical, endocrine, and immune changes in the rat'
Connor, TJ;Kelly, JP;Leonard, BE (1997) 'Forced swim test-induced neurochemical, endocrine, and immune changes in the rat'. Pharmacology Biochemistry And Behavior, 58 :961-967 [Details]
(1997) 'Behavioural and neurochemical effects of dizocilpine in the olfactory bulbectomized rat model of depression'
Redmond, AM;Kelly, JP;Leonard, BE (1997) 'Behavioural and neurochemical effects of dizocilpine in the olfactory bulbectomized rat model of depression'. Pharmacology Biochemistry And Behavior, 58 :355-359 [Details]
(1998) 'Effect of single dose of imipramine on some immunotoxicological parameters in the rat'
Dredge, K;Kelly, JP;Leonard, BE (1998) 'Effect of single dose of imipramine on some immunotoxicological parameters in the rat'. Medical Science Research, 26 :789-792 [Details]
(1998) 'Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat'
Connor, TJ;McNamara, MG;Finn, D;Currid, A;O'Malley, M;Redmond, AM;Kelly, JP;Leonard, BE (1998) 'Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat'. Immunopharmacology, 38 :253-260 [Details]
(1998) 'Forced swim test-induced endocrine and immune changes in the rat: Effect of subacute desipramine treatment'
Connor, TJ;Kelly, JP;Leonard, BE (1998) 'Forced swim test-induced endocrine and immune changes in the rat: Effect of subacute desipramine treatment'. Pharmacology Biochemistry And Behavior, 59 :171-177 [Details]
(1998) 'beta-Amyloid(Phe(SO3H)(24))25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation'
Harkany, T;O'Mahony, S;Kelly, JP;Soos, K;Toro, I;Penke, B;Luiten, PGM;Nyakas, C;Gulya, K;Leonard, BE (1998) 'beta-Amyloid(Phe(SO3H)(24))25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation'. Behavioural Brain Research, 90 :133-145 [Details]
(1999) 'Effects of acute and chronic antidepressant administration on phencyclidine (PCP) induced locomotor hyperactivity'
Redmond, AM;Harkin, A;Kelly, JP;Leonard, BE (1999) 'Effects of acute and chronic antidepressant administration on phencyclidine (PCP) induced locomotor hyperactivity'. European Neuropsychopharmacology, 9 :165-170 [Details]
(1999) 'Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression'
Harkin, A;Kelly, JP;McNamara, M;Connor, TJ;Dredge, K;Redmond, A;Leonard, BE (1999) 'Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression'. European Journal Of Pharmacology, 364 :123-132 [Details]
(1999) 'The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients'
Kelly, JP;Nicolau, G;Redmond, A;Leonard, BE;Noble, J;Sverdlov, L;Molinar, R;Kastin, AJ;Ehrensing, RH;Feighner, JP (1999) 'The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients'. Journal Of Affective Disorders, 55 :231-235 [Details]
(1999) 'Acute toxicity profile of maprotiline in the rat'
Darcy, P;Dredge, K;Kellehir, P;Kelly, JP;Leonard, BE;Chambers, PL (1999) 'Acute toxicity profile of maprotiline in the rat'. Pharmacology & Toxicology, 85 :276-281 [Details]
(1999) 'Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat'
Shen, Y;Connor, TJ;Nolan, Y;Kelly, JP;Leonard, BE (1999) 'Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat'. Life Sciences, 65 :1773-1786 [Details]
(1999) 'Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1 beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats'
Dredge, K;Connor, TJ;Kelly, JP;Leonard, BE (1999) 'Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1 beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats'. International Immunopharmacology, 21 :663-673 [Details]
(1999) 'The determination of the optimal dose of milnacipran in the olfactory bulbectomized rat model of depression'
Redmond, AM;Kelly, JP;Leonard, BE (1999) 'The determination of the optimal dose of milnacipran in the olfactory bulbectomized rat model of depression'. Pharmacology Biochemistry And Behavior, 62 :619-623 [Details]
(1999) 'Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat'
Connor, TJ;Kelliher, P;Harkin, A;Kelly, JP;Leonard, BE (1999) 'Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat'. European Journal Of Pharmacology, 379 :125-133 [Details]
(1999) 'Effects of chronic dietary supplementation with omega 3 and omega 6 fatty acid rich oils on lipopolysaccharide-induced behavioural responses and interleukin-1 beta secretion in the rat'
Shen, Y;Connor, TJ;Kelly, JP;Leonard, BE (1999) 'Effects of chronic dietary supplementation with omega 3 and omega 6 fatty acid rich oils on lipopolysaccharide-induced behavioural responses and interleukin-1 beta secretion in the rat'. Medical Science Research, 27 :291-294 [Details]
(1999) 'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: modification by the selective 5-HT1A receptor antagonist WAY 100635'
Cryan, JF;Kelliher, P;Kelly, JP;Leonard, BE (1999) 'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: modification by the selective 5-HT1A receptor antagonist WAY 100635'. Journal Of Psychopharmacology, 13 :278-283 [Details]
(1999) 'An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression'
Kelly, JP;Leonard, BE (1999) 'An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression'. European Neuropsychopharmacology, 9 :101-105 [Details]
(1999) 'Metyrapone displays antidepressant-like properties in preclinical paradigms'
Healy, DG;Harkin, A;Cryan, JF;Kelly, JP;Leonard, BE (1999) 'Metyrapone displays antidepressant-like properties in preclinical paradigms'. Journal Of Psychopharmacology, 145 :303-308 [Details]
(1999) 'Comparative effects of various antidepressant drugs and the immunosuppressant dexamethasone on the T-lymphocyte proliferative response in vitro'
Dredge, K;Connor, TJ;Kelly, JP;Leonard, BF (1999) 'Comparative effects of various antidepressant drugs and the immunosuppressant dexamethasone on the T-lymphocyte proliferative response in vitro'. Medical Science Research, 27 :773-774 [Details]
(1999) '3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat'
Connor, TJ;McNamara, MG;Kelly, JP;Leonard, BE (1999) '3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat'. Human Psychopharmacology-Clinical And Experimental, 14 :95-104 [Details]
(2000) 'Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action'
Cryan, JF;Harkin, A;Naughton, M;Kelly, JP;Leonard, BE (2000) 'Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action'. European Journal Of Pharmacology, 390 :275-285 [Details]
(2000) 'Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test'
Connor, TJ;Kelliher, P;Shen, Y;Harkin, A;Kelly, JP;Leonard, BE (2000) 'Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test'. Pharmacology Biochemistry And Behavior, 65 :591-597 [Details]
(2000) 'Test conditions influence the response to a drug challenge in rodents'
Harkin, A;Kelly, JP;Frawley, J;O'Donnell, JM;Leonard, BE (2000) 'Test conditions influence the response to a drug challenge in rodents'. Pharmacology Biochemistry And Behavior, 65 :389-398 [Details]
(2000) 'Effects of reboxetine and sertraline treatments alone and in combination on the binding properties of cortical NMDA and beta 1-adrenergic receptors in an animal model of depression'
Harkin, A;Nally, R;Kelly, JP;Leonard, BE (2000) 'Effects of reboxetine and sertraline treatments alone and in combination on the binding properties of cortical NMDA and beta 1-adrenergic receptors in an animal model of depression'. Journal Of Neural Transmission (Vienna, Austria : 1996), 107 :1213-1227 [Details]
(2000) 'Varying responses to the rat forced-swim test under diurnal and nocturnal conditions'
Kelliher, P;Connor, TJ;Harkin, A;Sanchez, C;Kelly, JP;Leonard, BE (2000) 'Varying responses to the rat forced-swim test under diurnal and nocturnal conditions'. Physiology & Behavior, 69 :531-539 [Details]
(2000) 'Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1 beta and TNF-alpha secretion following an in vivo lipopolysaccharide challenge'
Connor, TJ;Kelly, JP;McGee, M;Leonard, BE (2000) 'Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1 beta and TNF-alpha secretion following an in vivo lipopolysaccharide challenge'. Life Sciences, 67 :1601-1612 [Details]
(2000) 'An assessment of the acute effects of the serotonin releasers methylenedioxymethamphetamine, methylenedioxyamphetamine and fenfluramine on immunity in rats'
Connor, TJ;Kelly, JP;Leonard, BE (2000) 'An assessment of the acute effects of the serotonin releasers methylenedioxymethamphetamine, methylenedioxyamphetamine and fenfluramine on immunity in rats'. Immunopharmacology, 46 :223-235 [Details]
(2000) 'Olfactory bulbectomy provokes a suppression of interleukin-1 beta and tumour necrosis factor-alpha production in response to an in vivo challenge with lipopolysaccharide: Effect of chronic desipramine treatment'
Connor, TJ;Harkin, A;Kelly, JP;Leonard, BE (2000) 'Olfactory bulbectomy provokes a suppression of interleukin-1 beta and tumour necrosis factor-alpha production in response to an in vivo challenge with lipopolysaccharide: Effect of chronic desipramine treatment'. Neuroimmunomodulation, 7 :27-35 [Details]
(2000) 'Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain'
Nolan, Y;Connor, TJ;Kelly, JP;Leonard, BE (2000) 'Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain'. Journal Of Neural Transmission (Vienna, Austria : 1996), 107 :1393-1401 [Details]
(2001) 'Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats'
Harkin, A;Connor, TJ;Mulrooney, J;Kelly, JP;Leonard, BE (2001) 'Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats'. Life Sciences, 68 :1367-1382 [Details]
(2001) 'The toxicity profile of a single dose of paroxetine: An alternative approach to acute toxicity testing in the rat'
Ryan, PM;Kelly, JP;Chambers, PL;Leonard, BE (2001) 'The toxicity profile of a single dose of paroxetine: An alternative approach to acute toxicity testing in the rat'. Pharmacology & Toxicology, 88 :59-66 [Details]
(2001) 'Methylenedioxymethamphetamine (MDMA; 'Ecstasy') suppresses antigen specific IgG(2a) and IFN-gamma production'
Connor, TJ;Connelly, DB;Kelly, JP (2001) 'Methylenedioxymethamphetamine (MDMA; 'Ecstasy') suppresses antigen specific IgG(2a) and IFN-gamma production'. Immunology Letters, 78 :67-73 [Details]
(2001) 'Modulation of MK-801-induced behaviour by noradrenergic agents in mice'
Harkin, A;Morris, K;Kelly, JP;O'Donnell, JM;Leonard, BE (2001) 'Modulation of MK-801-induced behaviour by noradrenergic agents in mice'. Journal Of Psychopharmacology, 154 :177-188 [Details]
(2001) 'beta-amyloid((1-42))-induced cholinergic lesions in rat nucleus basalis bidirectionally modulate serotonergic innervation of the basal forebrain and cerebral cortex'
Harkany, T;O'Mahony, S;Keijser, J;Kelly, JP;Konya, C;Borostyankoi, ZA;Gorcs, TJ;Zarandi, M;Penke, B;Leonard, BE;Luiten, PGM (2001) 'beta-amyloid((1-42))-induced cholinergic lesions in rat nucleus basalis bidirectionally modulate serotonergic innervation of the basal forebrain and cerebral cortex'. Neurobiology Of Disease, 8 :667-678 [DOI] [Details]
(2001) 'Methylenedioxymethamphetamine-induced suppression of interleukin-1 beta and tumour necrosis factor-alpha is not mediated by serotonin'
Connor, TJ;Dennedy, MC;Harkin, A;Kelly, JP (2001) 'Methylenedioxymethamphetamine-induced suppression of interleukin-1 beta and tumour necrosis factor-alpha is not mediated by serotonin'. European Journal Of Pharmacology, 418 :147-152 [Details]
(2002) 'Fenfluramine-induced immunosuppression: an in vivo analysis'
Connor, TJ;Kelly, JP (2002) 'Fenfluramine-induced immunosuppression: an in vivo analysis'. European Journal Of Pharmacology, 455 :175-185 [Details]
(2002) 'Reduction in preference for saccharin by repeated unpredictable stress in mice and its prevention by imipramine'
Harkin, A;Houlihan, DD;Kelly, JP (2002) 'Reduction in preference for saccharin by repeated unpredictable stress in mice and its prevention by imipramine'. Journal Of Psychopharmacology, 16 :115-123 [Details]
(2002) 'Physiological and behavioral responses to stress: What does a rat find stressful?'
Harkin, A;Connor, TJ;O'Donnell, JM;Kelly, JP (2002) 'Physiological and behavioral responses to stress: What does a rat find stressful?'. Lab Animal, 31 :42-50 [Details]
(2002) 'Inhibition of constitutive nitric oxide production increases the severity of lipopolysaccharide-induced sickness behaviour: A role for TNF-alpha'
Connor, TJ;O'Sullivan, J;Nolan, Y;Kelly, JP (2002) 'Inhibition of constitutive nitric oxide production increases the severity of lipopolysaccharide-induced sickness behaviour: A role for TNF-alpha'. Neuroimmunomodulation, 10 :367-378 [DOI] [Details]
(2002) 'A study of VitalView (TM) for behavioural and physiological monitoring in laboratory rats'
Harkin, A;O'Donnell, JM;Kelly, JP (2002) 'A study of VitalView (TM) for behavioural and physiological monitoring in laboratory rats'. Physiology & Behavior, 77 :65-77 [Details]
(2002) 'The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis'
Darcy, P;Kelly, JP;Leonard, BE;Henry, JA (2002) 'The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis'. Toxicology letters, 128 :207-214 [Details]
(2003) 'A combined and comparative study of physiologic and behavioral parameters in a systemic toxicity test'
Harkin, AJ;O'Donnell, JM;Kelly, JP (2003) 'A combined and comparative study of physiologic and behavioral parameters in a systemic toxicity test'. Contemporary Topics In Laboratory Animal Science, 42 :31-38 [Details]
(2003) 'Methylenendioxyamphetamine produces serotonin nerve terminal loss and diminished behavioural and neurochemical responses to the antidepressant fluoxetine'
Harkin, A;Shanahan, E;Kelly, JP;Connor, TJ (2003) 'Methylenendioxyamphetamine produces serotonin nerve terminal loss and diminished behavioural and neurochemical responses to the antidepressant fluoxetine'. European Journal Of Neuroscience, 18 :1021-1027 [DOI] [Details]
(2003) 'Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors'
Harkin, A;Connor, TJ;Walsh, A;St John, N;Kelly, JP (2003) 'Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors'. Neuropharmacology, 44 :616-623 [DOI] [Details]
(2003) 'Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test'
Kelliher, P;Kelly, JP;Leonard, BE;Sanchez, C (2003) 'Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test'. Psychoneuroendocrinology, 28 :332-347 [DOI] [Details]
(2003) 'Identification of the expression of inhibitory gamma subunit of phosphodiesterase-6 in non-retinal murine tissues'
Venugopal, J;Boyle, N;Kelly, JP (2003) 'Identification of the expression of inhibitory gamma subunit of phosphodiesterase-6 in non-retinal murine tissues'. Current Science, 84 :1227-1231 [Details]
(2003) 'A toxicokinetic study of nickel-induced immunosuppression in rats'
Harkin, A;Hynes, MJ;Masterson, E;Kelly, JP;O'Donnell, JM;Connor, TJ (2003) 'A toxicokinetic study of nickel-induced immunosuppression in rats'. Immunopharmacology And Immunotoxicology, 25 :655-670 [DOI] [Details]
(2004) 'Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test'
Harkin, A;Connor, TJ;Burns, MP;Kelly, JP (2004) 'Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test'. European Neuropsychopharmacology, 14 :274-281 [Details]
(2004) 'Caffeine suppresses TNF-alpha production via activation of the cyclic AMP/protein kinase A pathway'
Horrigan, LA;Kelly, JP;Connor, TJ (2004) 'Caffeine suppresses TNF-alpha production via activation of the cyclic AMP/protein kinase A pathway'. International Immunopharmacology, 4 :1409-1417 [DOI] [Details]
(2005) 'The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory regions (vol 19, pg A37, 2005)'
Roche, M;Diamond, M;Lonergan, I;Keeney, G;Kelly, JP;Finn, DP (2005) 'The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory regions (vol 19, pg A37, 2005)'. Journal Of Psychopharmacology, 19 [Details]
(2005) 'Acute stress suppresses pro-inflammatory cytokines TNF-alpha and IL-1 beta independent of a catecholamine-driven increase in IL-10 production'
Connor, TJ;Brewer, C;Kelly, JP;Harkin, A (2005) 'Acute stress suppresses pro-inflammatory cytokines TNF-alpha and IL-1 beta independent of a catecholamine-driven increase in IL-10 production'. Journal Of Neuroimmunology, 159 :119-128 [DOI] [Details]
(2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'
Roche, M;Diamond, M;Kelly, JP;Finn, DP (2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'. Journal Of Neuroimmunology, 181 :57-67 [DOI] [Details]
(2006) 'Antidepressants suppress production of the Th-1 cytokine interferon-gamma, independent of monoamine transporter blockade'
Diamond, M;Kelly, JP;Connor, TJ (2006) 'Antidepressants suppress production of the Th-1 cytokine interferon-gamma, independent of monoamine transporter blockade'. European Neuropsychopharmacology, 16 :481-490 [DOI] [Details]
(2007) 'Chronic fluoxetine treatment attenuates stressor-induced changes in temperature, heart rate, and neuronal activation in the olfactory bulbectomized rat'
Roche, M;Harkin, A;Kelly, JP (2007) 'Chronic fluoxetine treatment attenuates stressor-induced changes in temperature, heart rate, and neuronal activation in the olfactory bulbectomized rat'. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology, 32 :1312-1320 [DOI] [Details]
(2008) 'An investigation of the value of the Tetrahymena pyriformis as a test organism for assessing the acute toxicity of antidepressants'
Uma, S;Kelly, JP;Rajasekaran, SK (2008) 'An investigation of the value of the Tetrahymena pyriformis as a test organism for assessing the acute toxicity of antidepressants'. Biomedical Research-India, 19 :37-40 [Details]
(2008) 'Trans-species assessment of antidepressant activity in a rodent model of depression'
Roche, M;Shanahan, E;Harkin, A;Kelly, JP (2008) 'Trans-species assessment of antidepressant activity in a rodent model of depression'. Pharmacological Reports, 60 :404-408 [Details]
(2008) 'Effects of Gamma Irradiation and Pasteurization on the Nutritive Composition of Commercially Available Animal Diets'
Caulfield, CD;Cassidy, JP;Kelly, JP (2008) 'Effects of Gamma Irradiation and Pasteurization on the Nutritive Composition of Commercially Available Animal Diets'. Journal Of The American Association For Laboratory Animal Science, 47 :61-66 [Details]
(2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'
Roche, M;Kelly, JP;O'Driscoll, M;Finn, DP (2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'. Immunology, 125 :263-271 [DOI] [Details]
(2009) 'The Experimental Induction of Leukoencephalomyelopathy in Cats'
Caulfield, CD;Kelly, JP;Jones, BR;Worrall, S;Conlon, L;Palmer, AC;Cassidy, JP (2009) 'The Experimental Induction of Leukoencephalomyelopathy in Cats'. Veterinary Pathology, 46 :1258-1269 [DOI] [Details]
(2017) 'Consequences of Oral Gavage during Gestation and Lactation on Rat Dams and the Neurodevelopment and Behavior of Their Offspring'
McDonnell-Dowling, K;Kleefeld, S;Kelly, JP (2017) 'Consequences of Oral Gavage during Gestation and Lactation on Rat Dams and the Neurodevelopment and Behavior of Their Offspring'. Journal Of The American Association For Laboratory Animal Science, 56 :79-83 [Details]
(2017) 'Dose-Dependent Effects of Binge-Like Methamphetamine Dosing on Dopamine and Neurotrophin Levels in Rat Brain'
Santos, AMD,Kelly, JP,Doyle, KM (2017) 'Dose-Dependent Effects of Binge-Like Methamphetamine Dosing on Dopamine and Neurotrophin Levels in Rat Brain'. Neuropsychobiology, 75 :63-71 [DOI] [Details]
(2018) 'Interventions for the manegement of obesity in people with bipolar disorder (Protocol)'
Agnes Tully Tully A, Murphy E, Smyth S, Conway Y, Geddes J, Devane D, Kelly JP, Jordan (2018) 'Interventions for the manegement of obesity in people with bipolar disorder (Protocol)'. Cochrane Database Of Systematic Reviews, (issue 4):1-15 [DOI] [Details]
(2018) 'Modulation of the central opioid system as an antidepressant target in rodent models'
McHugh, KL;Kelly, JP (2018) 'Modulation of the central opioid system as an antidepressant target in rodent models'. Temporal Sampling And Representation Updating, 239 :49-87 [DOI] [Details]
(2019) 'Effect of a binge-like dosing regimen of methamphetamine on dopamine levels and tyrosine hydroxylase expressing neurons in the rat brain'
Santos, AMD,Kelly, JP,Dockery, P,Doyle, KM (2019) 'Effect of a binge-like dosing regimen of methamphetamine on dopamine levels and tyrosine hydroxylase expressing neurons in the rat brain'. Progress In Neuro-Psychopharmacology & Biological Psychiatry, 89 :303-309 [DOI] [ARAN Link] [Details]
(2019) 'Locomotor and anti-immobility effects of buprenorphine in combination with the opioid receptor modulator samidorphan in rats'
Burke, NN,Ferdousi, M,Deaver, DR,Finn, DP,Roche, M,Kelly, JP (2019) 'Locomotor and anti-immobility effects of buprenorphine in combination with the opioid receptor modulator samidorphan in rats'. Neuropharmacology, 146 :327-336 [DOI] [ARAN Link] [Details]
(2017) 'Dose-dependent effects of binge-like methamphetamine dosing on dopamine and neurotrophin levels in rat brain'
Moreira da Silva Santos, A, Kelly, JP & Doyle, KM (2017) 'Dose-dependent effects of binge-like methamphetamine dosing on dopamine and neurotrophin levels in rat brain'. Neuropsychobiology, [ARAN Link] [Details]
(2017) 'Consequences of Oral Gavage during Gestation and Lactation on Rat Dams and the Neurodevelopment and Behavior of Their Offspring'
McDonnell-Dowling, K,Kleefeld, S,Kelly, JP (2017) 'Consequences of Oral Gavage during Gestation and Lactation on Rat Dams and the Neurodevelopment and Behavior of Their Offspring'. Journal Of The American Association For Laboratory Animal Science, 56 :79-83 [Details]
(2015) 'Development and Characterization of a Novel, Anatomically Relevant Rat Model of Acute Postoperative Pain'
Bree, D,Moriarty, O,Mahony, CM,Morris, B,Bannerton, K,Broom, DC,Kelly, JP,Roche, M,Finn, DP (2015) 'Development and Characterization of a Novel, Anatomically Relevant Rat Model of Acute Postoperative Pain'. Journal Of Pain, 16 :421-435 [DOI] [ARAN Link] [Details]
(2015) 'Aspirin and anti-inflammatory drugs for the prevention of dementia (Protocol)'
Jordan, F., McGuinness, B., Murphy, K., Passmore, P., Kelly, JP, Devane, D (2015) 'Aspirin and anti-inflammatory drugs for the prevention of dementia (Protocol)'. Cochrane database of systematic reviews (Online), (1) [Details]
(2014) 'Methamphetamine exposure during pregnancy at pharmacological doses produces neurodevelopmental and behavioural effects in rat offspring'
McDonnell-Dowling, K,Donlon, M,Kelly, JP (2014) 'Methamphetamine exposure during pregnancy at pharmacological doses produces neurodevelopmental and behavioural effects in rat offspring'. International Journal Of Developmental Neuroscience, 35 :42-51 [DOI] [Details]
(2012) 'Neurokinin-1 receptor deletion modulates behavioural and neurochemical alterations in an animal model of depression'
Roche, M., Kerr, D.M., Hunt, S.P. and Kelly, J.P. (2012) 'Neurokinin-1 receptor deletion modulates behavioural and neurochemical alterations in an animal model of depression'. Behavioural Brain Research, 228 (0):91-98 [DOI] [ARAN Link] [Details]
(2012) 'An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat'
Simpson, J. and Kelly, J.P. (2012) 'An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat'. Behavioural Brain Research, [Details]
(2012) 'Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase'
Butler, RK,Ford, GK,Hogan, M,Roche, M,Doyle, KM,Kelly, JP,Kendall, DA,Chapman, V,Finn, DP (2012) 'Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase'. Journal Of Psychopharmacology, 26 :83-91 [DOI] [ARAN Link] [Details]
(2011) 'The impact of environmental enrichment in laboratory rats--behavioural and neurochemical aspects'
Simpson, J., and Kelly, J.P. (2011) 'The impact of environmental enrichment in laboratory rats--behavioural and neurochemical aspects'. Behavioural Brain Research, 12 :246-264 [Details]
(2010) 'Complete Book: : Principles of CNS Drug Development: from test tube to patient'
Kelly J. (2010) 'Complete Book: : Principles of CNS Drug Development: from test tube to patient'. [Details]
(2009) 'The Experimental Induction of Leukoencephalomyelopathy in Cats'
Caulfield, CD,Kelly, JP,Jones, BR,Worrall, S,Conlon, L,Palmer, AC,Cassidy, JP (2009) 'The Experimental Induction of Leukoencephalomyelopathy in Cats'. Veterinary Pathology, 46 :1258-1269 [DOI] [Details]
(2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'
Roche M, Kelly JP, O'Driscoll M, Finn DP (2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'. Immunology, 125 (2):263-271 [DOI] [Details]
(2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'
Roche M, Kelly JP, O'Driscoll M, Finn DP (2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'. Journal of Neuroimmunology, 192 (2):162-162 [Details]
(2008) 'An investigation of the value of the Tetrahymena pyriformis as a test organism for assessing the acute toxicity of antidepressants'
Uma, S,Kelly, JP,Rajasekaran, SK (2008) 'An investigation of the value of the Tetrahymena pyriformis as a test organism for assessing the acute toxicity of antidepressants'. Biomedical Research-India, 19 :37-40 [Details]
(2008) 'Trans-species assessment of antidepressant activity in a rodent model of depression'
Roche M, Shanahan E, Harkin A, Kelly JP (2008) 'Trans-species assessment of antidepressant activity in a rodent model of depression'. Pharmacological Reports, 60 (0):404-408 [DOI] [Details]
(2008) 'Effects of Gamma Irradiation and Pasteurization on the Nutritive Composition of Commercially Available Animal Diets'
Caulfield, CD,Cassidy, JP,Kelly, JP (2008) 'Effects of Gamma Irradiation and Pasteurization on the Nutritive Composition of Commercially Available Animal Diets'. Journal Of The American Association For Laboratory Animal Science, 47 :61-66 [ARAN Link] [Details]
(2008) 'Comparison of the behavioural pharmacology of the Lister-Hooded with 2 commonly utilised albino rat strains'
Roche, M., Kelly, J.P., O'Driscoll, M. and Finn D.P. (2008) 'Comparison of the behavioural pharmacology of the Lister-Hooded with 2 commonly utilised albino rat strains'. Prog Neuropsychopharmacol Biol Psychiatry, 32 :1816-1823 [Details]
(2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'
Roche, M,Kelly, JP,O'Driscoll, M,Finn, DP (2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'. Immunology, 125 :263-271 [DOI] [Details]
(2008) 'A review of the neuropharmacological properties of khat'
Roche, M., Harkin, A. and Kelly J.P. (2008) 'A review of the neuropharmacological properties of khat'. Prog Neuropsychopharmacol Biol Psychiatry, 32 :1147-1166 [Details]
(2007) 'Development of a home cage locomotor tracking system capable of detecting the stimulant and sedative properties of drugs in rats'
Dunne, F., O'Halloran, A. and Kelly, J.P. (2007) 'Development of a home cage locomotor tracking system capable of detecting the stimulant and sedative properties of drugs in rats'. Prog. Neuropsychopharmacol. Biol. Psychiatry, 31 :1456-1463 [Details]
(2007) 'Chronic fluoxetine treatment attenuates stressor-induced changes in temperature, heart rate, and neuronal activation in the olfactory bulbectomized rat'
Roche, M,Harkin, A,Kelly, JP (2007) 'Chronic fluoxetine treatment attenuates stressor-induced changes in temperature, heart rate, and neuronal activation in the olfactory bulbectomized rat'. Neuropsychopharmacology, 32 :1312-1320 [DOI] [Details]
(2007) 'Leukoencephalomyelopathy in specific pathogen-free cats'
Cassidy, JP,Caulfield, C,Jones, BR,Worrall, S,Conlon, L,Palmer, AC,Kelly, J (2007) 'Leukoencephalomyelopathy in specific pathogen-free cats'. Veterinary Pathology, 44 :912-916 [Details]
(2006) 'Antidepressants suppress production of the Th-1 cytokine interferon-gamma, independent of monoamine transporter blockade'
Diamond, M,Kelly, JP,Connor, TJ (2006) 'Antidepressants suppress production of the Th-1 cytokine interferon-gamma, independent of monoamine transporter blockade'. European Neuropsychopharmacology, 16 :481-490 [DOI] [Details]
(2006) 'Immunomodulatory effects of caffeine: Friend or foe?'
Horrigan, LA,Kelly, JP,Connor, TJ (2006) 'Immunomodulatory effects of caffeine: Friend or foe?'. Pharmacology And Therapeutics, :877-892 [DOI] [Details]
(2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'
Roche M, Diamond M, Kelly JP, Finn DP (2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'. Journal Of Neuroimmunology, 181 (1-2):57-67 [DOI] [Details]
(2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'
Roche, M,Diamond, M,Kelly, JP,Finn, DP (2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'. Journal Of Neuroimmunology, 181 :57-67 [DOI] [Details]
(2006) 'Immodulatory effects of caffeine: friend or foe?'
Horrigan, L.A., Kelly, J.P. and Connor, T.J. (2006) 'Immodulatory effects of caffeine: friend or foe?'. Pharmacol. Ther, 111 :877-892 [Details]
(2005) 'Methylenedioxymethamphetamine suppresses production of the proinflammatory cytokine tumor necrosis factor-alpha independent of a beta-adrenoceptor-mediated increase in interleukin-10'
Connor, T. J., Harkin, A. and Kelly, J. P. (2005) 'Methylenedioxymethamphetamine suppresses production of the proinflammatory cytokine tumor necrosis factor-alpha independent of a beta-adrenoceptor-mediated increase in interleukin-10'. Journal of Pharmacology & Experimental Therapeutics, 312 :134-143 [Details]
(2005) 'Acute stress suppresses pro-inflammatory cytokines TNF-alpha and IL-1 beta independent of a catecholamine-driven increase in IL-10 production'
Connor, TJ,Brewer, C,Kelly, JP,Harkin, A (2005) 'Acute stress suppresses pro-inflammatory cytokines TNF-alpha and IL-1 beta independent of a catecholamine-driven increase in IL-10 production'. Journal Of Neuroimmunology, 159 :119-128 [DOI] [Details]
(2004) 'Caffeine suppresses TNF-alpha production via activation of the cyclic AMP/protein kinase A pathway'
Horrigan, LA,Kelly, JP,Connor, TJ (2004) 'Caffeine suppresses TNF-alpha production via activation of the cyclic AMP/protein kinase A pathway'. International Immunopharmacology, 4 :1409-1417 [DOI] [Details]
(2004) 'Caffeine inhibits monocyte and neutrophil chemotaxis at concentrations relevant to normal human consumption. In:'
Horrigan, L.A., Diamond, M., Connor, T.J. and Kelly, J.P. (2004) 'Caffeine inhibits monocyte and neutrophil chemotaxis at concentrations relevant to normal human consumption. In:'. Int. Cytokine Soc, :49-54 [Details]
(2004) 'Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test'
Harkin, A,Connor, TJ,Burns, MP,Kelly, JP (2004) 'Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test'. European Neuropsychopharmacology, 14 :274-281 [Details]
(2003) 'Novel therapeutic targets for the treatment of depression'
Kelly, J. P. (2003) 'Novel therapeutic targets for the treatment of depression'. Current Medicinal Chemistry, 3 :311-322 [Details]
(2003) 'A toxicokinetic study of nickel-induced immunosuppression in rats'
Harkin, A,Hynes, MJ,Masterson, E,Kelly, JP,O'Donnell, JM,Connor, TJ (2003) 'A toxicokinetic study of nickel-induced immunosuppression in rats'. Immunopharmacology And Immunotoxicology, 25 :655-670 [DOI] [Details]
(2003) 'A review of the relevance and validity of olfactory bulbectomy as a model of depression'
Harkin, A ., Kelly, J. P. and Leonard, B. E. (2003) 'A review of the relevance and validity of olfactory bulbectomy as a model of depression'. Clinical Neuroscience Research, 3 :253-262 [Details]
(2003) 'Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors'
Harkin, A,Connor, TJ,Walsh, A,St John, N,Kelly, JP (2003) 'Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors'. Neuropharmacology, 44 :616-623 [DOI] [Details]
(2003) 'Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test'
Kelliher, P,Kelly, JP,Leonard, BE,Sanchez, C (2003) 'Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test'. Psychoneuroendocrinology, 28 :332-347 [DOI] [Details]
(2003) 'Identification of the expression of inhibitory gamma subunit of phosphodiesterase-6 in non-retinal murine tissues'
Venugopal, J,Boyle, N,Kelly, JP (2003) 'Identification of the expression of inhibitory gamma subunit of phosphodiesterase-6 in non-retinal murine tissues'. Current Science, 84 :1227-1231 [Details]
(2003) 'Methylenendioxyamphetamine produces serotonin nerve terminal loss and diminished behavioural and neurochemical responses to the antidepressant fluoxetine'
Harkin, A,Shanahan, E,Kelly, JP,Connor, TJ (2003) 'Methylenendioxyamphetamine produces serotonin nerve terminal loss and diminished behavioural and neurochemical responses to the antidepressant fluoxetine'. European Journal Of Neuroscience, 18 :1021-1027 [DOI] [Details]
(2003) 'A combined and comparative study of physiologic and behavioral parameters in a systemic toxicity test'
Harkin, AJ,O'Donnell, JM,Kelly, JP (2003) 'A combined and comparative study of physiologic and behavioral parameters in a systemic toxicity test'. Contemporary Topics In Laboratory Animal Science, 42 :31-38 [Details]
(2002) 'A study of VitalView (TM) for behavioural and physiological monitoring in laboratory rats'
Harkin, A,O'Donnell, JM,Kelly, JP (2002) 'A study of VitalView (TM) for behavioural and physiological monitoring in laboratory rats'. Physiology & Behavior, 77 :65-77 [DOI] [Details]
(2002) 'Fenfluramine-induced immunosuppression: an in vivo analysis'
Connor, TJ,Kelly, JP (2002) 'Fenfluramine-induced immunosuppression: an in vivo analysis'. European Journal Of Pharmacology, 455 :175-185 [DOI] [Details]
(2002) 'Inhibition of constitutive nitric oxide production increases the severity of lipopolysaccharide-induced sickness behaviour: A role for TNF-alpha'
Connor, TJ,O'Sullivan, J,Nolan, Y,Kelly, JP (2002) 'Inhibition of constitutive nitric oxide production increases the severity of lipopolysaccharide-induced sickness behaviour: A role for TNF-alpha'. Neuroimmunomodulation, 10 :367-378 [DOI] [Details]
(2002) 'Reduction in preference for saccharin by repeated unpredictable stress in mice and its prevention by imipramine'
Harkin, A,Houlihan, DD,Kelly, JP (2002) 'Reduction in preference for saccharin by repeated unpredictable stress in mice and its prevention by imipramine'. Journal Of Psychopharmacology, 16 :115-123 [Details]
(2002) 'Physiological and behavioral responses to stress: What does a rat find stressful?'
Harkin, A,Connor, TJ,O'Donnell, JM,Kelly, JP (2002) 'Physiological and behavioral responses to stress: What does a rat find stressful?'. Lab Animal, 31 :42-50 [Details]
(2002) 'The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis'
Darcy, P,Kelly, JP,Leonard, BE,Henry, JA (2002) 'The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis'. Toxicology Letters, 128 :207-214 [DOI] [Details]
(2001) 'Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat'
O'Loinsigh, E.D., Boland, G., Kelly, J.P. and O'Boyle K.M. (2001) 'Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat'. Prog Neuropsychopharmacol Biol Psychiatry, 25 :621-638 [Details]
(2001) 'The toxicity profile of a single dose of paroxetine: An alternative approach to acute toxicity testing in the rat'
Ryan, PM,Kelly, JP,Chambers, PL,Leonard, BE (2001) 'The toxicity profile of a single dose of paroxetine: An alternative approach to acute toxicity testing in the rat'. Pharmacology & Toxicology, 88 :59-66 [Details]
(2001) 'Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats'
Harkin, A,Connor, TJ,Mulrooney, J,Kelly, JP,Leonard, BE (2001) 'Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats'. Life Sciences, 68 :1367-1382 [Details]
(2001) 'Modulation of MK-801-induced behaviour by noradrenergic agents in mice'
Harkin, A,Morris, K,Kelly, JP,O'Donnell, JM,Leonard, BE (2001) 'Modulation of MK-801-induced behaviour by noradrenergic agents in mice'. Psychopharmacology, 154 :177-188 [Details]
(2001) 'beta-amyloid((1-42))-induced cholinergic lesions in rat nucleus basalis bidirectionally modulate serotonergic innervation of the basal forebrain and cerebral cortex'
Harkany, T,O'Mahony, S,Keijser, J,Kelly, JP,Konya, C,Borostyankoi, ZA,Gorcs, TJ,Zarandi, M,Penke, B,Leonard, BE,Luiten, PGM (2001) 'beta-amyloid((1-42))-induced cholinergic lesions in rat nucleus basalis bidirectionally modulate serotonergic innervation of the basal forebrain and cerebral cortex'. Neurobiology Of Disease, 8 :667-678 [Details]
(2001) 'Methylenedioxymethamphetamine-induced suppression of interleukin-1 beta and tumour necrosis factor-alpha is not mediated by serotonin'
Connor, TJ,Dennedy, MC,Harkin, A,Kelly, JP (2001) 'Methylenedioxymethamphetamine-induced suppression of interleukin-1 beta and tumour necrosis factor-alpha is not mediated by serotonin'. European Journal Of Pharmacology, 418 :147-152 [Details]
(2001) 'Methylenedioxymethamphetamine (MDMA; 'Ecstasy') suppresses antigen specific IgG(2a) and IFN-gamma production'
Connor, TJ,Connelly, DB,Kelly, JP (2001) 'Methylenedioxymethamphetamine (MDMA; 'Ecstasy') suppresses antigen specific IgG(2a) and IFN-gamma production'. Immunology Letters, 78 :67-73 [Details]
(2000) 'Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action'
Cryan, JF,Harkin, A,Naughton, M,Kelly, JP,Leonard, BE (2000) 'Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action'. European Journal Of Pharmacology, 390 :275-285 [Details]
(2000) 'An assessment of the acute effects of the serotonin releasers methylenedioxymethamphetamine, methylenedioxyamphetamine and fenfluramine on immunity in rats'
Connor, TJ,Kelly, JP,Leonard, BE (2000) 'An assessment of the acute effects of the serotonin releasers methylenedioxymethamphetamine, methylenedioxyamphetamine and fenfluramine on immunity in rats'. Immunopharmacology, 46 :223-235 [Details]
(2000) 'Test conditions influence the response to a drug challenge in rodents'
Harkin, A,Kelly, JP,Frawley, J,O'Donnell, JM,Leonard, BE (2000) 'Test conditions influence the response to a drug challenge in rodents'. Pharmacology Biochemistry And Behavior, 65 :389-398 [Details]
(2000) 'Varying responses to the rat forced-swim test under diurnal and nocturnal conditions'
Kelliher, P,Connor, TJ,Harkin, A,Sanchez, C,Kelly, JP,Leonard, BE (2000) 'Varying responses to the rat forced-swim test under diurnal and nocturnal conditions'. Physiology & Behavior, 69 :531-539 [Details]
(2000) 'The role of animal models in the development of anti-depressants'
Kelly, J.P. (2000) 'The role of animal models in the development of anti-depressants'. J. Depression and Anxiety, 3 :22-27 [Details]
(2000) 'Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain'
Nolan, Y,Connor, TJ,Kelly, JP,Leonard, BE (2000) 'Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain'. Journal Of Neural Transmission, 107 :1393-1401 [Details]
(2000) 'Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1 beta and TNF-alpha secretion following an in vivo lipopolysaccharide challenge'
Connor, TJ,Kelly, JP,McGee, M,Leonard, BE (2000) 'Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1 beta and TNF-alpha secretion following an in vivo lipopolysaccharide challenge'. Life Sciences, 67 :1601-1612 [Details]
(2000) 'Olfactory bulbectomy provokes a suppression of interleukin-1 beta and tumour necrosis factor-alpha production in response to an in vivo challenge with lipopolysaccharide: Effect of chronic desipramine treatment'
Connor, TJ,Harkin, A,Kelly, JP,Leonard, BE (2000) 'Olfactory bulbectomy provokes a suppression of interleukin-1 beta and tumour necrosis factor-alpha production in response to an in vivo challenge with lipopolysaccharide: Effect of chronic desipramine treatment'. Neuroimmunomodulation, 7 :27-35 [Details]
(2000) 'Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test'
Connor, TJ,Kelliher, P,Shen, Y,Harkin, A,Kelly, JP,Leonard, BE (2000) 'Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test'. Pharmacology Biochemistry And Behavior, 65 :591-597 [Details]
(2000) 'Effects of reboxetine and sertraline treatments alone and in combination on the binding properties of cortical NMDA and beta 1-adrenergic receptors in an animal model of depression'
Harkin, A,Nally, R,Kelly, JP,Leonard, BE (2000) 'Effects of reboxetine and sertraline treatments alone and in combination on the binding properties of cortical NMDA and beta 1-adrenergic receptors in an animal model of depression'. Journal Of Neural Transmission, 107 :1213-1227 [Details]
(1999) 'Effects of acute and chronic antidepressant administration on phencyclidine (PCP) induced locomotor hyperactivity'
Redmond, AM,Harkin, A,Kelly, JP,Leonard, BE (1999) 'Effects of acute and chronic antidepressant administration on phencyclidine (PCP) induced locomotor hyperactivity'. European Neuropsychopharmacology, 9 :165-170 [Details]
(1999) 'Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat'
Shen, Y,Connor, TJ,Nolan, Y,Kelly, JP,Leonard, BE (1999) 'Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat'. Life Sciences, 65 :1773-1786 [Details]
(1999) 'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: modification by the selective 5-HT1A receptor antagonist WAY 100635'
Cryan, JF,Kelliher, P,Kelly, JP,Leonard, BE (1999) 'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: modification by the selective 5-HT1A receptor antagonist WAY 100635'. Journal Of Psychopharmacology, 13 :278-283 [Details]
(1999) '3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat'
Connor, TJ,McNamara, MG,Kelly, JP,Leonard, BE (1999) '3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat'. Human Psychopharmacology-Clinical And Experimental, 14 :95-104 [Details]
(1999) 'Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat'
Connor, TJ,Kelliher, P,Harkin, A,Kelly, JP,Leonard, BE (1999) 'Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat'. European Journal Of Pharmacology, 379 :125-133 [Details]
(1999) 'The determination of the optimal dose of milnacipran in the olfactory bulbectomized rat model of depression'
Redmond, AM,Kelly, JP,Leonard, BE (1999) 'The determination of the optimal dose of milnacipran in the olfactory bulbectomized rat model of depression'. Pharmacology Biochemistry And Behavior, 62 :619-623 [Details]
(1999) 'The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients'
KELLY, JP et al. (1999) 'The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients'. JOURNAL OF AFFECTIVE DISORDERS, 55 :231-235 [Details]
(1999) 'Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1 beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats'
Dredge, K,Connor, TJ,Kelly, JP,Leonard, BE (1999) 'Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1 beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats'. International Journal Of Immunopharmacology, 21 :663-673 [Details]
(1999) 'Effects of chronic dietary supplementation with omega 3 and omega 6 fatty acid rich oils on lipopolysaccharide-induced behavioural responses and interleukin-1 beta secretion in the rat'
Shen, Y,Connor, TJ,Kelly, JP,Leonard, BE (1999) 'Effects of chronic dietary supplementation with omega 3 and omega 6 fatty acid rich oils on lipopolysaccharide-induced behavioural responses and interleukin-1 beta secretion in the rat'. Medical Science Research, 27 :291-294 [Details]
(1999) 'Metyrapone displays antidepressant-like properties in preclinical paradigms'
Healy, DG,Harkin, A,Cryan, JF,Kelly, JP,Leonard, BE (1999) 'Metyrapone displays antidepressant-like properties in preclinical paradigms'. Psychopharmacology, 145 :303-308 [Details]
(1999) 'Comparative effects of various antidepressant drugs and the immunosuppressant dexamethasone on the T-lymphocyte proliferative response in vitro'
Dredge, K,Connor, TJ,Kelly, JP,Leonard, BF (1999) 'Comparative effects of various antidepressant drugs and the immunosuppressant dexamethasone on the T-lymphocyte proliferative response in vitro'. Medical Science Research, 27 :773-774 [Details]
(1999) 'Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression'
Harkin, A,Kelly, JP,McNamara, M,Connor, TJ,Dredge, K,Redmond, A,Leonard, BE (1999) 'Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression'. European Journal Of Pharmacology, 364 :123-132 [Details]
(1999) 'An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression'
Kelly, JP,Leonard, BE (1999) 'An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression'. European Neuropsychopharmacology, 9 :101-105 [Details]
(1999) 'Acute toxicity profile of maprotiline in the rat'
Darcy, P,Dredge, K,Kellehir, P,Kelly, JP,Leonard, BE,Chambers, PL (1999) 'Acute toxicity profile of maprotiline in the rat'. Pharmacology & Toxicology, 85 :276-281 [Details]
(1998) 'Models and responses in depression and aggression'
Kelly, J.P. and Leonard, B.E. (1998) 'Models and responses in depression and aggression'. Biochemical Society Transactions, 26 :61-65 [Details]
(1998) 'beta-Amyloid(Phe(SO3H)(24))25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation'
Harkany, T,O'Mahony, S,Kelly, JP,Soos, K,Toro, I,Penke, B,Luiten, PGM,Nyakas, C,Gulya, K,Leonard, BE (1998) 'beta-Amyloid(Phe(SO3H)(24))25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation'. Behavioural Brain Research, 90 :133-145 [Details]
(1998) 'Effect of single dose of imipramine on some immunotoxicological parameters in the rat'
Dredge, K,Kelly, JP,Leonard, BE (1998) 'Effect of single dose of imipramine on some immunotoxicological parameters in the rat'. Medical Science Research, 26 :789-792 [Details]
(1998) 'Forced swim test-induced endocrine and immune changes in the rat: Effect of subacute desipramine treatment'
Connor, TJ,Kelly, JP,Leonard, BE (1998) 'Forced swim test-induced endocrine and immune changes in the rat: Effect of subacute desipramine treatment'. Pharmacology Biochemistry And Behavior, 59 :171-177 [Details]
(1998) 'Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat'
Connor, TJ,McNamara, MG,Finn, D,Currid, A,O'Malley, M,Redmond, AM,Kelly, JP,Leonard, BE (1998) 'Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat'. Immunopharmacology, 38 :253-260 [Details]
(1997) 'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat'
Cryan, JF,Redmond, AM,Kelly, JP,Leonard, BE (1997) 'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat'. European Neuropsychopharmacology, 7 :109-114 [Details]
(1997) 'Forced swim test-induced neurochemical, endocrine, and immune changes in the rat'
Connor, TJ,Kelly, JP,Leonard, BE (1997) 'Forced swim test-induced neurochemical, endocrine, and immune changes in the rat'. Pharmacology Biochemistry And Behavior, 58 :961-967 [Details]
(1997) 'An appraisal of the pharmacological and toxicological effects of a single oral administration of 3,4-methylenedioxymethamphetamine (MDMA) in the rat'
DeSouza, I,Kelly, JP,Harkin, AJ,Leonard, BE (1997) 'An appraisal of the pharmacological and toxicological effects of a single oral administration of 3,4-methylenedioxymethamphetamine (MDMA) in the rat'. Pharmacology & Toxicology, 80 :207-210 [Details]
(1997) 'Effect of phencyclidine and apomorphine administration in the olfactory bulbectomised rat'
McGrath, C,Kelly, JP,McHugh, MF,Leonard, BE (1997) 'Effect of phencyclidine and apomorphine administration in the olfactory bulbectomised rat'. Medical Science Research, 25 :829-831 [Details]
(1997) 'Effect of acute desipramine treatment on immunological parameters in the rat'
Connor, TJ,Kelly, JP,Leonard, BE (1997) 'Effect of acute desipramine treatment on immunological parameters in the rat'. Medical Science Research, 25 :209-211 [Details]
(1997) 'Behavioural and neurochemical effects of dizocilpine in the olfactory bulbectomized rat model of depression'
Redmond, AM,Kelly, JP,Leonard, BE (1997) 'Behavioural and neurochemical effects of dizocilpine in the olfactory bulbectomized rat model of depression'. Pharmacology Biochemistry And Behavior, 58 :355-359 [Details]
(1997) 'BIMT 17: a putative antidepressant with a fast onset of action?'
Borsini, F., Cesana, R., Kelly, J., Leonard, B.E., McNamara, M., Richards, J. and Seiden, L. (1997) 'BIMT 17: a putative antidepressant with a fast onset of action?'. Psychopharmacology, 134 :378-386 [Details]
(1997) 'Protective effects of vanoxeamine (GBR 12909) against ischaemia-induced hyperactivity and neurodegeneration in gerbil model of cerebral ischaemia'
Maginn, M., Kelly, J.P. and Leonard, B.E. (1997) 'Protective effects of vanoxeamine (GBR 12909) against ischaemia-induced hyperactivity and neurodegeneration in gerbil model of cerebral ischaemia'. Pharmacology Biochemistry And Behavior, 56 :727-735 [Details]
(1997) 'Organotin comopunds in trimethyltin-treated rats and in human brain in Alzheimer’s Disease'
Martin, F., Corrigan, F.M., Donard, O.F.X., Kelly, J., Besson, J.A.O. and Horrobin, D.F. (1997) 'Organotin comopunds in trimethyltin-treated rats and in human brain in Alzheimer’s Disease'. Human & Experimental Toxicology, 16 :512-515 [Details]
(1997) 'The olfactory bulbectomized rat as a model of depression: an update'
Kelly, J.P., Wrynn, A.S. and Leonard, B.E. (1997) 'The olfactory bulbectomized rat as a model of depression: an update'. Pharmacology And Therapeutics, 74 :299-316 [Details]
(1996) 'Some behavioural and neurochemical effects of ipsapirone in two rodent models of depression'
McNamara, MG,Kelly, JP,Leonard, BE (1996) 'Some behavioural and neurochemical effects of ipsapirone in two rodent models of depression'. Journal Of Psychopharmacology, 10 :126-133 [Details]
(1996) 'The effect of chronic antidepressant treatment on alcohol intake in rats'
Redrobe, J.P., Kelly, J.P., Chambers, P.L. and Leonard, B.E. (1996) 'The effect of chronic antidepressant treatment on alcohol intake in rats'. Medical Science Research, 24 :25-26 [Details]
(1996) 'Behavioural effects of chronic glycine in the olfactory bulbectomised rat in the 'open field' test and on phencyclidine (PCP)-induced hyperactivity'
Redmond, AM,Kelly, JP,Leonard, BE (1996) 'Behavioural effects of chronic glycine in the olfactory bulbectomised rat in the 'open field' test and on phencyclidine (PCP)-induced hyperactivity'. Medical Science Research, 24 :55-56 [Details]
(1996) 'Home cage and open-field locomotor activity responses in singly housed olfactory bulbectomised rats'
Kelly, JP,Norman, TR,OHalloran, A,Leonard, BE (1996) 'Home cage and open-field locomotor activity responses in singly housed olfactory bulbectomised rats'. Medical Science Research, 24 :335-337 [Details]
(1996) 'The plasma glucose profile of individual rats in response to a single subcutaneous injection of streptozotocin'
MacSweeney, CP,McGarvey, C,Kelly, JP,Leonard, BE (1996) 'The plasma glucose profile of individual rats in response to a single subcutaneous injection of streptozotocin'. Medical Science Research, 24 :13-14 [Details]
(1996) 'Does the serenic eltoprazine have antidepressant potential? - An investigation in three rodent paradigms'
Cryan, JF,Redmond, AM,Kelly, JP,Leonard, BE (1996) 'Does the serenic eltoprazine have antidepressant potential? - An investigation in three rodent paradigms'. Medical Science Research, 24 :719-720 [Details]
(1996) 'The characterization of oxotremorine-induced hypothermic response in the rat'
Ryan, PM,Kelly, JP,Chambers, PL,Leonard, BE (1996) 'The characterization of oxotremorine-induced hypothermic response in the rat'. Pharmacology & Toxicology, 79 :238-240 [Details]
(1996) 'Effects of chronic desipramine on waiting behaviour for a food reward in olfactory bulbectomized rats'
Kelly, JP,Leonard, BE (1996) 'Effects of chronic desipramine on waiting behaviour for a food reward in olfactory bulbectomized rats'. Journal Of Psychopharmacology, 10 :153-156 [Details]
(1995) 'THE EFFECT OF ACUTE MDMA ADMINISTRATION ON BODY-TEMPERATURE, SERUM CORTICOSTERONE AND NEUROTRANSMITTER CONCENTRATIONS IN MALE AND FEMALE RATS'
MCNAMARA, MG,KELLY, JP,LEONARD, BE (1995) 'THE EFFECT OF ACUTE MDMA ADMINISTRATION ON BODY-TEMPERATURE, SERUM CORTICOSTERONE AND NEUROTRANSMITTER CONCENTRATIONS IN MALE AND FEMALE RATS'. Human Psychopharmacology-Clinical And Experimental, 10 :373-383 [Details]
(1995) 'EFFECTS OF OLFACTORY BULBECTOMY AND CHRONIC AMITRIPTYLINE TREATMENT ON PHENCYCLIDINE (PCP)-INDUCED HYPERACTIVITY'
REDMOND, AM,KELLY, JP,LEONARD, BE (1995) 'EFFECTS OF OLFACTORY BULBECTOMY AND CHRONIC AMITRIPTYLINE TREATMENT ON PHENCYCLIDINE (PCP)-INDUCED HYPERACTIVITY'. Medical Science Research, 23 :351-352 [Details]
(1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT TREATMENT FOLLOWING ACUTE ADMINISTRATION OF THE NEUROTOXIN TRIMETHYLTIN IN THE RAT'
REDROBE, JP,KELLY, JP,CHAMBERS, PL,LEONARD, BE (1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT TREATMENT FOLLOWING ACUTE ADMINISTRATION OF THE NEUROTOXIN TRIMETHYLTIN IN THE RAT'. Medical Science Research, 23 :407-408 [Details]
(1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT ADMINISTRATION ON THE CONDITIONED TASTE-AVERSION TO 8-OHDPAT IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
REDMOND, AM,KELLY, JP,LEONARD, BE (1995) 'EFFECT OF CHRONIC ANTIDEPRESSANT ADMINISTRATION ON THE CONDITIONED TASTE-AVERSION TO 8-OHDPAT IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :487-488 [Details]
(1995) 'The influence of route of administration on the diabetogenic effects of streptozotocin in the rat'
MacSweeney, CP,Kelly, JP,Leonard, BE (1995) 'The influence of route of administration on the diabetogenic effects of streptozotocin in the rat'. Medical Science Research, 23 :811-812 [Details]
(1995) 'SOME BEHAVIORAL-EFFECTS OF METHIOTHEPIN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
MCNAMARA, MG,KELLY, JP,LEONARD, BE (1995) 'SOME BEHAVIORAL-EFFECTS OF METHIOTHEPIN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :583-585 [Details]
(1995) 'EFFECT OF ACUTE ADMINISTRATION OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE (MDMA) ON TEMPERATURE AND LOCOMOTOR-ACTIVITY IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
MCGRATH, C,KELLY, JP,MCHUGH, MF,LEONARD, BE (1995) 'EFFECT OF ACUTE ADMINISTRATION OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE (MDMA) ON TEMPERATURE AND LOCOMOTOR-ACTIVITY IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :199-201 [Details]
(1995) 'SOME BEHAVIORAL AND NEUROCHEMICAL ASPECTS OF SUBACUTE (+/-)3,4-METHYLENEDIOXYMETHAMPHETAMINE ADMINISTRATION IN RATS'
MCNAMARA, MG,KELLY, JP,LEONARD, BE (1995) 'SOME BEHAVIORAL AND NEUROCHEMICAL ASPECTS OF SUBACUTE (+/-)3,4-METHYLENEDIOXYMETHAMPHETAMINE ADMINISTRATION IN RATS'. Pharmacology Biochemistry And Behavior, 52 :479-484 [Details]
(1995) 'THE BEHAVIORAL-EFFECTS OF MILNACIPRAN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'
REDMOND, AM,KELLY, JP,LEONARD, BE (1995) 'THE BEHAVIORAL-EFFECTS OF MILNACIPRAN IN THE OLFACTORY BULBECTOMISED RAT MODEL OF DEPRESSION'. Medical Science Research, 23 :533-534 [Details]
(1995) 'An investigation of the hyperactive response in the olfactory bulbectomised rat model of depression'
Kelly, JP,Leonard, BE (1995) 'An investigation of the hyperactive response in the olfactory bulbectomised rat model of depression'. Medical Science Research, 23 :837-838 [Details]
(1995) 'The behavioural effects of milnacipran in the olfactory bulbectomised rat model of depression'
Redmond, A.M., Kelly, J.P. and Leonard, B.E. (1995) 'The behavioural effects of milnacipran in the olfactory bulbectomised rat model of depression'. Medical Science Research, 23 :533-534 [Details]
(1995) 'Effects of dietary l-histidine administration on trimethyltin-induced behavioural changes in the rat'
Mullen, A.M., Kelly, J. and Leonard, B.E. (1995) 'Effects of dietary l-histidine administration on trimethyltin-induced behavioural changes in the rat'. Medical Science Research, 23 :403-404 [Details]
(1995) 'The effect of acute MDMA administration on body temperature, serum corticosterone and neurotransmitter concentrations in male and female rats'
McNamara, M.G., Kelly, J.P. and Leonard, B.E. (1995) 'The effect of acute MDMA administration on body temperature, serum corticosterone and neurotransmitter concentrations in male and female rats'. Human Psychopharmacology-Clinical And Experimental, 10 :373-383 [Details]
(1995) 'Effects of chronic antidepressant administration on the conditioned taste aversion to 8-OHDPAT in the olfactory bulbectomised rat model of depression'
Redmond, A.M., Kelly, J.P. and Leonard, B.E. (1995) 'Effects of chronic antidepressant administration on the conditioned taste aversion to 8-OHDPAT in the olfactory bulbectomised rat model of depression'. Medical Science Research, 23 :487-488 [Details]
(1995) 'The effect of 2-amino-phospho propionic acid (AP-3) in the gerbil model of ischaemia'
Maginn, M., Caldwell, M., Kelly, J.P. and Leonard, B.E. (1995) 'The effect of 2-amino-phospho propionic acid (AP-3) in the gerbil model of ischaemia'. European Journal Of Pharmacology, 282 :259-262 [Details]
(1995) 'NG-Nitro-L-arginine methyl ester protects against lipid peroxidation in the gerbil following cerebral ischaemia'
Caldwell, M., O'Neill, M., Earley, B., Kelly, J.P. and Leonard, B.E. (1995) 'NG-Nitro-L-arginine methyl ester protects against lipid peroxidation in the gerbil following cerebral ischaemia'. European Journal Of Pharmacology, 285 :203-206 [Details]
(1995) 'The  receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia'
O’Neill, M., Caldwell, M., Earley, B., Canney, M., O’Halloran, A., Kelly, J., Leonard, B.E. and Junien, J.L. (1995) 'The  receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia'. European Journal Of Pharmacology, 283 :217-225 [Details]
(1994) 'THE EFFECT OF TIANEPTINE AND SERTRALINE IN 3 ANIMAL-MODELS OF DEPRESSION'
KELLY, JP,LEONARD, BE (1994) 'THE EFFECT OF TIANEPTINE AND SERTRALINE IN 3 ANIMAL-MODELS OF DEPRESSION'. Neuropharmacology, 33 :1011-1016 [Details]
(1994) 'ALTERATIONS IN IMMUNE AND ENDOCRINE PARAMETERS FOLLOWING OLFACTORY BULBECTOMY'
SONG, C,KELLY, JP,LEONARD, BE (1994) 'ALTERATIONS IN IMMUNE AND ENDOCRINE PARAMETERS FOLLOWING OLFACTORY BULBECTOMY'. Medical Science Research, 22 :593-595 [Details]
(1994) 'DOSE-DEPENDENT BEHAVIORAL-EFFECTS OF PHENCYCLIDINE (PCP)'
NSIMBA, SED,KELLY, JP,LEONARD, BE (1994) 'DOSE-DEPENDENT BEHAVIORAL-EFFECTS OF PHENCYCLIDINE (PCP)'. Medical Science Research, 22 :207-209 [Details]
(1994) 'EFFECTS OF ACUTE PHENCYCLIDINE (PCP) ON DIFFERENT ROUTES OF ADMINISTRATION ON BEHAVIORAL PARAMETERS IN RATS'
NSIMBA, SED,KELLY, JP,LEONARD, BE (1994) 'EFFECTS OF ACUTE PHENCYCLIDINE (PCP) ON DIFFERENT ROUTES OF ADMINISTRATION ON BEHAVIORAL PARAMETERS IN RATS'. Medical Science Research, 22 :399-401 [Details]
(1994) 'THE EFFECT OF STRESSFUL BEHAVIORAL EXPOSURE ON ENDOCRINE AND IMMUNE PARAMETERS IN THE RAT'
SONG, C,KELLY, JP,LEONARD, BE (1994) 'THE EFFECT OF STRESSFUL BEHAVIORAL EXPOSURE ON ENDOCRINE AND IMMUNE PARAMETERS IN THE RAT'. Stress Medicine, 10 :239-245 [Details]
(1993) 'Is the state of leucocyte adhesiveness/aggregation an immune marker of stress in the olfactory bulbectomized rat?'
Song, C., Kelly, J. and Leonard, B.E. (1993) 'Is the state of leucocyte adhesiveness/aggregation an immune marker of stress in the olfactory bulbectomized rat?'. Stress Medicine, 9 :255-258 [Details]

Books

  Year Publication
(2010) Principles of CNS Drug Development: From Test Tube to Patient Wiley UK.
Dr John Patrick Kelly (2010) Principles of CNS Drug Development: From Test Tube to Patient Wiley UK. [Details]

Book Chapters

  Year Publication
(2022) 'The olfactory bulbectomized rodent remains a valuable preclinical model of depression and antidepressant activity'
Roche M, Kelly JP (2022) 'The olfactory bulbectomized rodent remains a valuable preclinical model of depression and antidepressant activity' In: Psychiatric Vulnerability, Mood, and Anxiety Disorders. New York, NY: Humana. [Details]

Conference Publications

  Year Publication
(2017) British Pharmacological Society (BPS) conference, Pharmacology 2017
McHugh KL, Calcagno P, Clarke M, Everman D, Sanchez C, Roche M, Finn DP, Kelly JP (2017) An assessment of single versus paired-housing on social cognition in the 3-chamber sociability test in the olfactory bulbectomized (OB) rat model of depression British Pharmacological Society (BPS) conference, Pharmacology 2017 [Details]
(2019) British Neuroscience Association Festival of Neuroscience
Ferdousi M, Calcagno P, Aggarwal S, Sanchez C, Smith K, Kelly JP, Roche M, Finn DP (2019) Differential effect of kappa opioid receptor modulation in the Wistar-Kyoto rat model of hyperalgesia associated with negative affective state British Neuroscience Association Festival of Neuroscience [Details]
(2019) European College of Neuropsychopharmacology (ECNP), 32nd ECNP Congress
McHugh KL, Calcagno P, Ferdousi M, Sanchez C, Roche M, Finn DP, Kelly JP (2019) Alterations in the central opioid system following acute swim stress and olfactory bulbectomy in the rat European College of Neuropsychopharmacology (ECNP), 32nd ECNP Congress [ARAN Link] [Details]
(2017) 47th European Brain and Behaviour Society Meeting
Hughes EM, Flannery LE, Clarke M, Calcagno P, Kerr DM, Eyerman D, Sanchez C, Kelly, JP, Finn DP, Roche M (2017) Altered expression of mRNA encoding opioid peptides and receptors in discrete brain regions of the valproic acid animal model of social impairment 47th European Brain and Behaviour Society Meeting Bilbao, Spain, [Details]
(2018) British Pharmacological Society, Pharmacology 2018
Hughes EM, Thornton AM, Kerr DM, Clarke M, Calcagno P, Sanchez C, Kelly JP, Finn DP, Roche M (2018) Kappa opioid receptor-mediated modulation of social motivation and cognition in adolescent rats prenatally exposed to valproic acid British Pharmacological Society, Pharmacology 2018 [Details]
(2018) Society for Neuroscience conference
McHugh KL, Doherty H, Calcagno P, Clarke M, Eyerman D, Sanchez C, Roche M, Finn DP, Kelly JP (2018) Evaluation of the 3-chamber sociability test in the olfactory bulbectomized (OB) rat model of depression Society for Neuroscience conference [Details]
(2018) Problems of Drug Dependence 80th Annual Meeting
Cunningham JI, Burke NN, Todtenkopf MS, Finn DP, Roche M, Kelly JP, Sanchez C (2018) Samidorphan attenuates the effects of buprenorphine in rat models evaluating abuse potential Problems of Drug Dependence 80th Annual Meeting San Diego, [Details]
(2018) 11th Federation of European Neuroscience Societies (FENS) Forum of Neuroscience
Hughes EM, Thornton AM, Clarke M, Calcagno P, Sanchez C, Kelly JP, Finn DP, Roche M (2018) Kappa opioid receptor-mediated modulation of social motivation and cognition in adolescent rats 11th Federation of European Neuroscience Societies (FENS) Forum of Neuroscience [Details]
(1996) IRISH JOURNAL OF MEDICAL SCIENCE
Brehony, F;Kelly, JP;Leonard, BE (1996) An investigation of the behavioural and physiological effects of acute and chronic administration of metyrapone, challenged with (+/-)3,4-methylene-dioxymethamphetamine IRISH JOURNAL OF MEDICAL SCIENCE , pp.312-312 [Details]
(1996) IRISH JOURNAL OF MEDICAL SCIENCE
Harkin, AJ;Kelly, JP;Leonard, BE (1996) The comparative effects of long-term administration of sertraline, paroxetine, citalopram, fluoxetine and amitriptyline on monoamine content in rat brain IRISH JOURNAL OF MEDICAL SCIENCE , pp.311-311 [Details]
(1996) IRISH JOURNAL OF MEDICAL SCIENCE
Brehony, F;Kelly, JP;Leonard, BE (1996) An investigation of the effects of 8-hydroxy-2-(di-n-propylamino)-tetrlin (8-OH-DPAT), on behavioural parameters in rats treated acutely and chronically with metyrapone IRISH JOURNAL OF MEDICAL SCIENCE , pp.311-311 [Details]
(1996) IRISH JOURNAL OF MEDICAL SCIENCE
Brehony, F;Kelly, JP;Leonard, BE (1996) An investigation of the effects of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT), on behavioural parameters in rats treated acutely and chronically with metyrapone IRISH JOURNAL OF MEDICAL SCIENCE , pp.307-307 [Details]
(1997) PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Maginn, M;Kelly, JP;Leonard, BE (1997) Protective effects of vanoxeamine (GBR 12909) against ischaemia-induced hyperactivity and neurodegeneration in the gerbil model of cerebral ischaemia PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR , pp.727-735 [Details]
(1998) BIOCHEMICAL SOCIETY TRANSACTIONS
Healy, DG;Kelly, JP;Leonard, BE (1998) Corticosterone influences the NMDA receptor antagonist MK-801 induced hyperactivity in the rat BIOCHEMICAL SOCIETY TRANSACTIONS , pp.23-23 [Details]
(1998) BIOCHEMICAL SOCIETY TRANSACTIONS
Kelly, JP;Leonard, BE (1998) Models and responses in depression and aggression BIOCHEMICAL SOCIETY TRANSACTIONS , pp.61-65 [Details]
(2003) PROCEEDINGS OF THE INTERNATIONAL CYTOKINE SOCIETY ANNUAL MEETING
Horrigan, L;Diamond, M;Connor, T;Kelly, JP (2003) Caffeine inhibits monocyte and neutrophil chemotaxis at concentrations relevant to normal human consumption PROCEEDINGS OF THE INTERNATIONAL CYTOKINE SOCIETY ANNUAL MEETING , pp.49-54 [Details]
(2005) JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Connor, TJ;Harkin, A;Kelly, JP (2005) Methylenedioxymethamphetamine suppresses production of the proinflammatory cytokine tumor necrosis factor-alpha independent of a beta-adrenoceptor-mediated increase in interleukin-10 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS , pp.134-143 [DOI] [Details]
(2005) British Pharmacological Society meeting
Roche M, Diamond M, Lonergan I, Keeney G, Kelly JP, Finn DP (2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory cytokines in discrete rat brain regions British Pharmacological Society meeting Journal of Psychopharmacology 19(5), [Details]
(2005) Royal Academy of Medicine in Ireland Biomedical Section Meeting. Galway
Roche M, Diamond M, Lonergan I, Keeney G, Kelly JP, Finn DP (2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory cytokines in discrete rat brain regions Royal Academy of Medicine in Ireland Biomedical Section Meeting. Galway Proceedings, [Details]
(2006) British Pharmacological Society meeting
Roche M, Diamond M, Kelly JP, Finn DP (2006) Cannabinoid receptor-mediated modulation of lipopolysaccharide-induced alterations in cytokine levels in discrete brain regions and hypothalamo-pituitary-adrenal axis activity in rats British Pharmacological Society meeting Journal of Psychopharmacology 20(5), , pp.A14-A84 [Details]
(2006) International Cannabinoid Research Society Symposium
Roche M, Diamond M, Kelly JP, Finn DP (2006) Cannabinoid receptor-mediated modulation of lipopolysaccharide-induced alterations in peripheral cytokine levels, circulating lymphocytes and hypothalamo-pituitary-adrenal axis activity in rats International Cannabinoid Research Society Symposium 16th Annual Symposium on the Cannabinoids, International Cannabinoid Research Society, [Details]
(2006) International Cannabinoid Research Society Symposium
Roche M, O’Connor E, Diskin C, Kelly JP, Finn DP (2006) Effects of administration of the CB1 receptor antagonist SR141716A into the right basolateral amygdala on conditioned fear and associated analgesia in rats International Cannabinoid Research Society Symposium 16th Annual Symposium on the Cannabinoids, International Cannabinoid Research Society, [Details]
(2007) British Pharmacological Society meeting
Roche M, O’Driscoll M, Diamond M, Kelly JP, Finn DP (2007) Modulation of LPS-induced alterations in peripheral cytokine levels by the endocannabinoid system British Pharmacological Society meeting Proceedings, [Details]
(2008) International Society for Neuroimmunology Symposium
Roche M, Kelly JP, O’Driscoll M, Finn DP (2008) Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats International Society for Neuroimmunology Symposium Journal of Neuroimmunology 197 (2), [Details]
(2008) International Cannabinoid Research Society Symposium
Roche M, Kelly JP, O'Driscoll M, Finn DP. (2008) Inhibition of endocannabinoid degradation or transport in vivo modulates LPS-induced increases in circulating cytokine levels International Cannabinoid Research Society Symposium 18th Annual Symposium on the Cannabinoids, International Cannabinoid Research Society, [Details]
(2011) British Pharmacologcial Association summer meeting
Bree D, O’Mahony C, Morris B. Broom DC, Kelly JP, Roche M and Finn DP (2011) Investigation Of The Effects Of Diazepam And Amphetamine On Rat Locomotor Activity In The Home Cage And Open Field Using An Automated Approach British Pharmacologcial Association summer meeting Proceedings, [Details]
(2014) European College Neuropsychopharmacology Congress
Burke NN, Deaver DR, Finn DP, Roche M, Kelly JP (2014) The effects of subacute administration of buprenorphine and the novel opioid modulator samidorphan on home-cage locomotor activity in rats European College Neuropsychopharmacology Congress European Neuropsychopharmacology, Vol 24 Supplement 2, [Details]
(2015) European College Neuropsychopharmacology Congress
Burke NN, Deaver DR, Finn DP, Roche M, Kelly JP (2015) Chronic administration of buprenorphine in combination with samidorphan produces antidepressant-like effects in rats without locomotor sensitization European College Neuropsychopharmacology Congress Eur Neuropsychopharmacol. 2015, Vol 25, Supplement 2, , pp.S379-S380 [Details]
(2015) British Pharmacology Association Conference July 2015
Burke NN, Deaver DR, Finn DP, Roche M, Kelly JP. (2015) Buprenorphine, alone and in combination with the novel opioid receptor modulator samidorphan, displays antidepressant-like effects in two rat models British Pharmacology Association Conference July 2015 Journal of Psychopharmacology, Issue 29 (8), [Details]
(2005) European College of Neuropsychopharmacology Congress
Roche M, Harkin A, Kelly JP (2005) Chronic fluoxetine treatment attenuates stressor-induced changes in physiology and neuronal activation in the olfactory bulbectomized (OB) rat European College of Neuropsychopharmacology Congress European Neuropharmacology 15 (Suppl 3), [Details]
(2005) ECNP Workshop on Neuropsychopharmacology for Young Scientist, Nice
Roche M, Harkin A, Kelly JP (2005) Altered physiological responses to stress in the olfactory bulbectomized rat: normalisation by chronic fluoxetine treatment ECNP Workshop on Neuropsychopharmacology for Young Scientist, Nice European Neuropharmacology 15 (Suppl 1), [Details]
(2005) Royal Academy of Medicine in Ireland Biomedical Section Annual Meeting
Roche M, Kelly JP, Harkin A (2005) Chronic fluoxetine treatment normalises altered physiological responses to stress in the olfactory bulbectomized rat Royal Academy of Medicine in Ireland Biomedical Section Annual Meeting Irish Journal of Medical Science 174(1)es2:21, [Details]
(2004) European College of Neuropsychopharmacology Congress
Roche M, Shanahan E, Harkin A, Kelly JP (2004) Chronic imipramine treatment reverses olfactory bulbectomized-induced hyperactivity in three rodent species European College of Neuropsychopharmacology Congress European Neuropharmacology 14 (Suppl 3), [Details]
(2004) Federation of European Neuroscience Forum
Roche M, Harkin A, Kelly JP (2004) Fluoxetine attenuates “open field”-induced neuronal c-FOS expression in a regionally dependent manner in the olfactory bulbectomised rat Federation of European Neuroscience Forum Federation of European Neuroscience Forum Abstracts Vol. 2, [Details]
(2004) Royal Academy of Medicine in Ireland Biomedical Section Annual Meeting
Roche M, Harkin A, Kelly JP (2004) Comparison of novelty-induced activity in three rodent species following olfactory bulbectomy Royal Academy of Medicine in Ireland Biomedical Section Annual Meeting Irish Journal of Medical Science 173(2) e2:10, [Details]
(2016) British Pharmacological Society conference
McHugh KL, Doherty H, Deaver D, Roche M, Finn DP, Kelly JP (2016) An assessment of social cognition in the olfactory bulbectomized rat model of depression British Pharmacological Society conference Proceedings, [Details]
(2008) Inhibition of endocannabinoid degradation or transport in vivo modulates LPS-induced increases in circulating cytokine levels
Roche M, Kelly JP, O'Driscoll M, Finn DP (2008) ICRS 2008 Inhibition of endocannabinoid degradation or transport in vivo modulates LPS-induced increases in circulating cytokine levels [Details]
(2007) BPS 2007
Roche M, O'Driscoll M, Diamond M, Kelly JP, Finn DP (2007) Modulation of LPS-induced alterations in peripheral cytokine levels by the endocannabinoid system BPS 2007 [DOI] [Details]
(2006) BAP 2006
Roche M, Diamond M, Kelly JP, Finn DP (2006) Cannabinoid receptor-mediated modulation of lipopolysaccharide-induced alterations in cytokine levels in discrete brain regions and hypothalamo-pituitary-adrenal axis activity in rats BAP 2006 [Details]
(2006) ICRS 2006
Roche M, Diamond M, Kelly JP, Finn DP ( (2006) Cannabinoid receptor-mediated modulation of lipopolysaccharide-induced alterations in peripheral cytokine levels, circulating lymphocytes and hypothalamo-pituitary-adrenal axis activity in rats ICRS 2006 [Details]
(2006) ICRS 2006
Roche M, O'Connor E, Diskin C, Kelly JP, Finn DP (2006) Effects of administration of the CB1 receptor antagonist SR141716A into the right basolateral amygdala on conditioned fear and associated analgesia in rats ICRS 2006 [Details]
(2005) BAP 2005
Roche M, Diamond M, Lonergan I, Keeney G, Kelly JP, Finn DP (2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory cytokines in discrete rat brain regions BAP 2005 [Details]
(2005) Methylenedioxymethamphetamine suppresses production of the proinflammatory cytokine tumor necrosis factor-alpha independent of a beta-adrenoceptor-mediated increase in interleukin-10
Connor, TJ,Harkin, A,Kelly, JP (2005) JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Methylenedioxymethamphetamine suppresses production of the proinflammatory cytokine tumor necrosis factor-alpha independent of a beta-adrenoceptor-mediated increase in interleukin-10 , pp.134-143 [DOI] [Details]
(1998) Models and responses in depression and aggression
Kelly, JP,Leonard, BE (1998) BIOCHEMICAL SOCIETY TRANSACTIONS Models and responses in depression and aggression , pp.61-65 [Details]
(1998) BIOCHEMICAL SOCIETY TRANSACTIONS
KELLY, JP et al. (1998) Models and responses in depression and aggression BIOCHEMICAL SOCIETY TRANSACTIONS , pp.61-65 [Details]
(1998) Corticosterone influences the NMDA receptor antagonist MK-801 induced hyperactivity in the rat
Healy, DG,Kelly, JP,Leonard, BE (1998) BIOCHEMICAL SOCIETY TRANSACTIONS Corticosterone influences the NMDA receptor antagonist MK-801 induced hyperactivity in the rat , pp.23-23 [Details]
(1997) Protective effects of vanoxeamine (GBR 12909) against ischaemia-induced hyperactivity and neurodegeneration in the gerbil model of cerebral ischaemia
Maginn, M,Kelly, JP,Leonard, BE (1997) PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR Protective effects of vanoxeamine (GBR 12909) against ischaemia-induced hyperactivity and neurodegeneration in the gerbil model of cerebral ischaemia , pp.727-735 [Details]
(1996) An investigation of the effects of 8-hydroxy-2-(di-n-propylamino)-tetrlin (8-OH-DPAT), on behavioural parameters in rats treated acutely and chronically with metyrapone
Brehony, F,Kelly, JP,Leonard, BE (1996) IRISH JOURNAL OF MEDICAL SCIENCE An investigation of the effects of 8-hydroxy-2-(di-n-propylamino)-tetrlin (8-OH-DPAT), on behavioural parameters in rats treated acutely and chronically with metyrapone , pp.311-311 [Details]
(1996) The comparative effects of long-term administration of sertraline, paroxetine, citalopram, fluoxetine and amitriptyline on monoamine content in rat brain
Harkin, AJ,Kelly, JP,Leonard, BE (1996) IRISH JOURNAL OF MEDICAL SCIENCE The comparative effects of long-term administration of sertraline, paroxetine, citalopram, fluoxetine and amitriptyline on monoamine content in rat brain , pp.311-311 [Details]
(1996) An investigation of the behavioural and physiological effects of acute and chronic administration of metyrapone, challenged with (+/-)3,4-methylene-dioxymethamphetamine
Brehony, F,Kelly, JP,Leonard, BE (1996) IRISH JOURNAL OF MEDICAL SCIENCE An investigation of the behavioural and physiological effects of acute and chronic administration of metyrapone, challenged with (+/-)3,4-methylene-dioxymethamphetamine , pp.312-312 [Details]
(1996) An investigation of the effects of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT), on behavioural parameters in rats treated acutely and chronically with metyrapone
Brehony, F,Kelly, JP,Leonard, BE (1996) IRISH JOURNAL OF MEDICAL SCIENCE An investigation of the effects of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT), on behavioural parameters in rats treated acutely and chronically with metyrapone , pp.307-307 [Details]

Other Journals

  Year Publication
(2020) 'Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia'
McGuinness B, Passmore P, Kelly JP, Tudur Smith C, Murphy K, Devane D. (2020) 'Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia' Cochrane Database of Systematic Reviews, . [Details]
(2011) 'Cathinone derivatives: a review of their chemistry, pharmacology and toxicology'
Kelly, J.P. (2011) 'Cathinone derivatives: a review of their chemistry, pharmacology and toxicology' Drug Testing and Analysis, 3 :439-453. [Details]
(1997) 'Effect of chronic rafoxanide administration on behavioural and physiological parameters in the rat'
Nsimba, S.E.D., Kelly, J.P. and Leonard, B.E. (1997) 'Effect of chronic rafoxanide administration on behavioural and physiological parameters in the rat' Indian Journal of Pharmacology, 29 :289-295. [Details]
(1997) 'Effect of acute and chronic haloperidol administration and apomorphine challenge on the behavioural parameters in rats'
Nsimba, S.E.D., Kelly, J.P. and Leonard, B.E. (1997) 'Effect of acute and chronic haloperidol administration and apomorphine challenge on the behavioural parameters in rats' Indian Journal of Pharmacology, 29 :15-19. [Details]
(1997) 'The interaction between chlorpromazine and apomorphine on temperature in the rat'
Nsimba, S.E.D., Kelly, J.P. and Leonard, B.E. (1997) 'The interaction between chlorpromazine and apomorphine on temperature in the rat' Journal of Serotonin Research, 3 :161-167. [Details]
(1996) 'Single or repeated administration of selective serotonin reuptake inhibitors fail to modulate apomorphine-induced responses in the rat'
Harkin, A., Kelly, J.P., and Leonard, B.E. (1996) 'Single or repeated administration of selective serotonin reuptake inhibitors fail to modulate apomorphine-induced responses in the rat' Journal of Serotonin Research, 3 :49-58. [Details]
(1995) 'Thermoregulatory and locomotor activity responses of 3,4-methylenedioxymethamphetamine (MDMA) inmale and female rats'
McNamara, M.G., Kelly, J.P. and Leonard, B.E. (1995) 'Thermoregulatory and locomotor activity responses of 3,4-methylenedioxymethamphetamine (MDMA) inmale and female rats' Journal of Serotonin Research, 4 :275-282. [Details]
(1995) 'Neuroendocrine and behavioural effects of the serotonin releasers 3,4-methylenedioxymethamphetamine and fenfluramine in rats'
McGarvey, C., Kelly, J., O'Donnell, J.M. and Leonard, B.E. (1995) 'Neuroendocrine and behavioural effects of the serotonin releasers 3,4-methylenedioxymethamphetamine and fenfluramine in rats' Journal of Serotonin Research, 4 :257-265. [Details]
(1995) 'Effect of 8-OH-DPAT in the olfactory bulbectomized rat model of depression'
McNamara, M.G., Kelly, J.P. and Leonard, B.E. (1995) 'Effect of 8-OH-DPAT in the olfactory bulbectomized rat model of depression' Journal of Serotonin Research, 2 :91-99. [Details]
(1995) 'The effects of acute and chronic antidepressant treatments on temperature and locomotor activity responses to 8-OH-DPAT, clonidine and apomorphine'
Redmond, A.M., Kelly, J.P. and Leonard, B.E. (1995) 'The effects of acute and chronic antidepressant treatments on temperature and locomotor activity responses to 8-OH-DPAT, clonidine and apomorphine' Journal of Serotonin Research, 2 :139-148. [Details]
(1995) 'The contribution of pre-clinical drug evaluation in predicting the clinical profile of the selective serotonin reuptake inhibitor paroxetine'
Kelly, J.P. and Leonard, B.E. (1995) 'The contribution of pre-clinical drug evaluation in predicting the clinical profile of the selective serotonin reuptake inhibitor paroxetine' Journal of Serotonin Research, 2 :27-46. [Details]
(1995) 'MK-801 potentiated the acute neuroendocrine and behaviural effects of 3,4-methylenedioxymethamphetamine'
McGarvey, C., O’Donnell, J.M., Kelly, J.P. and Leonard, B.E. (1995) 'MK-801 potentiated the acute neuroendocrine and behaviural effects of 3,4-methylenedioxymethamphetamine' Journal of Serotonin Research, 3 :191-203. [Details]
(1995) 'The comparative effects of long-term administration of sertraline, paroxetine, citalopram, fluoxetine and amitriptyline on monoamine content in rat brain'
Harkin, A., Kelly, J.P. and Leonard, B.E. (1995) 'The comparative effects of long-term administration of sertraline, paroxetine, citalopram, fluoxetine and amitriptyline on monoamine content in rat brain' Journal of Serotonin Research, 2 :181-190. [Details]
(1994) 'Effects of olfactory bulbectomy on phencyclidine (PCP) induced behavioural changes'
Nsimba, S.E., Kelly, J.P. and Leonard, B.E. (1994) 'Effects of olfactory bulbectomy on phencyclidine (PCP) induced behavioural changes' Indian Journal of Pharmacology, 26 :136-140. [Details]
(1994) 'The effect of acute and chronic antidepressant treatment on MDMA-induced behavioural changes in rats'
Redrobe, J.P., Kelly, J.P., Chambers, P.L. and Leonard, B.E. (1994) 'The effect of acute and chronic antidepressant treatment on MDMA-induced behavioural changes in rats' Journal of Serotonin Research, 3 :215-219. [Details]
(1994) 'Effect of paroxetine and fluvoxamine on behavioural changes in a number of paradigms in the olfactory bulbectomized rat model of depression'
Redmond, A.M., Kelly, J.P. and Leonard, B.E. (1994) 'Effect of paroxetine and fluvoxamine on behavioural changes in a number of paradigms in the olfactory bulbectomized rat model of depression' Journal of Serotonin Research, 3 :199-205. [Details]

Conference Contributions

  Year Publication
International Association for the Study of Pain (IASP) 17th World Congress on Pain,
Ferdousi M, Calcagno P, Aggarwal S, Sanchez C, Kelly JP, Roche M, Finn DP Hyporesponsivity to morphine microinjected into the ventrolateral periaqueductal grey in Wistar-Kyoto versus Sprague-Dawley rats. [Poster Presentation], International Association for the Study of Pain (IASP) 17th World Congress on Pain, Boston, USA . [Details]
Royal Acadamy of Medicine in Ireland (RAMI) Section of Biomedical Sciences Annual Meeting 2017,
McHugh KL, Calcagno P, Clarke M, Everman D, Sanchez C, Roche M, Finn DP, Kelly JP A comparative assessment of single versus paired-housing on behavioural responses in the olfactory bulbectomised (OB) rat model of depression. [Poster Presentation], Royal Acadamy of Medicine in Ireland (RAMI) Section of Biomedical Sciences Annual Meeting 2017, Ireland . [Details]
Neuroscience Ireland Annual General Meeting 2017,
McHugh KL, Calcagno P, Clarke M, Everman D, Sanchez C, Roche M, Finn DP, Kelly JP A comparative assessment of single versus paired-housing on behavioural responses in the olfactory bulbectomised (OB) rat model of depression. [Poster Presentation], Neuroscience Ireland Annual General Meeting 2017, Ireland . [Details]

Abstract

  Year Publication
(2012) Exposure to open-field testing induces light-dependent reversal of the circadian rhythmicity of home cage locomotor activity in rats. Presented at the meeting of the Biomedical Sciences Section of the Royal Academy of Medicine in Ireland, Galway.
Bree D, O'Mahony C, Morris B, Broom DC, Kelly JP, Roche M, Finn DP (2012) Exposure to open-field testing induces light-dependent reversal of the circadian rhythmicity of home cage locomotor activity in rats. Presented at the meeting of the Biomedical Sciences Section of the Royal Academy of Medicine in Ireland, Galway. Abstract [Details]
(2011) MATERNAL ANTIDEPRESSANT EXPOSURE AND CNS DEVELOPMENT IN THE RAT OFFSPRING.
Kelly, JP,O'Brien, S (2011) MATERNAL ANTIDEPRESSANT EXPOSURE AND CNS DEVELOPMENT IN THE RAT OFFSPRING. Abstract [Details]
(2011) CONSEQUENCES OF IN UTERO EXPOSURE TO FLUOXETINE ON ADULT BEHAVIOUR IN THE RAT.
O'Brien, S,Kelly, JP (2011) CONSEQUENCES OF IN UTERO EXPOSURE TO FLUOXETINE ON ADULT BEHAVIOUR IN THE RAT. Abstract [Details]
(2011) Consequences of in utero methamphetamine exposure on behaviour in the adult rat.
O'Brien, S,Campadieu, N,Higgins, D,Kelly, JP (2011) Consequences of in utero methamphetamine exposure on behaviour in the adult rat. Abstract [Details]
(2010) EFFECTS OF IN UTERO ANTIDEPRESSANT ADMINISTRATION ON ADULT BEHAVIOUR IN THE RAT.
O'Brien, S,Kelly, JP (2010) EFFECTS OF IN UTERO ANTIDEPRESSANT ADMINISTRATION ON ADULT BEHAVIOUR IN THE RAT. Abstract [Details]
(2010) Comparative behavioural pharmacology of three rat strains.
Kelly, J,McDermott, C (2010) Comparative behavioural pharmacology of three rat strains. Abstract [Details]
(2005) Chronic fluoxetine treatment attenuates stressor-induced changes in physiology and neuronal activation in the olfactory bulbectornized (OB) rat.
Roche, M,Harkin, A,Kelly, JP (2005) Chronic fluoxetine treatment attenuates stressor-induced changes in physiology and neuronal activation in the olfactory bulbectornized (OB) rat. Abstract [Details]
(2005) The role of the endocannabinoid system in the right basolateral amygdala in conditioned fear and associated analgesia in rats. Irish Neuroscience Group Meeting.
O'Connor E, Roche M, Diskin C, Kelly JP, Finn DP (2005) The role of the endocannabinoid system in the right basolateral amygdala in conditioned fear and associated analgesia in rats. Irish Neuroscience Group Meeting. Offaly, Ireland: Abstract [Details]
(2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory cytokines in discrete rat brain regions. Royal Academy of Medicine in Ireland Biomedical Section Meeting.
Roche M, Diamond M, Lonergan I, Keeney G, Kelly JP, Finn DP (2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory cytokines in discrete rat brain regions. Royal Academy of Medicine in Ireland Biomedical Section Meeting. Galway, Ireland: Abstract [Details]
(2004) Chronic imipramine treatment reverses olfactory buibectomized-induced hyperactivity in three rodent species.
Roche, M,Shanahan, E,Harkin, A,Kelly, JP (2004) Chronic imipramine treatment reverses olfactory buibectomized-induced hyperactivity in three rodent species. Abstract [Details]
(2003) Effects of single and repeated administration of an adensosine A(2A) receptor antagonist in rodent models sensitive to antidepressant activity.
Redrobe, JP,Kelly, JP,Hogg, S (2003) Effects of single and repeated administration of an adensosine A(2A) receptor antagonist in rodent models sensitive to antidepressant activity. Abstract [Details]
(2003) Diminished behavioural and neurochemical responses to fluoxetine following prior treatment with methylenedioxyamphetamine.
Harkin, A,Shanahan, E,Kelly, JP,Connor, TJ (2003) Diminished behavioural and neurochemical responses to fluoxetine following prior treatment with methylenedioxyamphetamine. Abstract [Details]
(2002) Physiological and behavioural monitoring in rats in response to pharmacological agents and laboratory stressors with battery free telemetry.
Harkin, A,O'Donnell, JM,Kelly, JP (2002) Physiological and behavioural monitoring in rats in response to pharmacological agents and laboratory stressors with battery free telemetry. Abstract [Details]
(2001) Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses the primary IgG response to an antigenic challenge in rats.
Connor, TJ,Connelly, DB,Kelly, JP (2001) Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses the primary IgG response to an antigenic challenge in rats. Abstract [Details]
(2001) Evidence for a critical role of body temperature in the modulation of MDMA by drugs of abuse.
O'Loinsigh, E,Kelly, JP,O'Boyle, KM (2001) Evidence for a critical role of body temperature in the modulation of MDMA by drugs of abuse. Abstract [Details]
(2000) Co-administration of D-amphetamine alters the acute and long-term effects of 3,4-methylene-dioxymethamphetamine in rats.
O'Loinsigh, ED,Kelly, JP,O'Boyle, KM (2000) Co-administration of D-amphetamine alters the acute and long-term effects of 3,4-methylene-dioxymethamphetamine in rats. Abstract [Details]
(2000) Modulation of MK-801 response by noradrenergic agents in mice.
Harkin, A,Morris, K,Kelly, JP,Leonard, BE (2000) Modulation of MK-801 response by noradrenergic agents in mice. Abstract [Details]
(1996) An investigation of the antidepressant properties of 8-OH-DPAT and ipsapirone in rats.
McNamara, MG,Kelly, JP,Leonard, BE (1996) An investigation of the antidepressant properties of 8-OH-DPAT and ipsapirone in rats. Abstract [Details]
(1995) METABOTROPIC AND IONOTROPIC RECEPTOR ANTAGONISTS PREVENT THE NEURODEGENERATION SEEN FOLLOWING 5 MIN BILATERAL CAROTID OCCLUSION IN THE MONGOLIAN GERBIL MODEL OF CEREBRAL-ISCHEMIA.
MAGINN, M,CALDWELL, M,ONEILL, MJ,KELLY, JP,LEONARD, BE (1995) METABOTROPIC AND IONOTROPIC RECEPTOR ANTAGONISTS PREVENT THE NEURODEGENERATION SEEN FOLLOWING 5 MIN BILATERAL CAROTID OCCLUSION IN THE MONGOLIAN GERBIL MODEL OF CEREBRAL-ISCHEMIA. Abstract [Details]
(1993) DEXAMETHASONE SUPPRESSION OF CORTICOSTERONE SECRETION IN OLFACTORY BULBECTOMIZED RATS.
KELLY, JP,LEONARD, BE (1993) DEXAMETHASONE SUPPRESSION OF CORTICOSTERONE SECRETION IN OLFACTORY BULBECTOMIZED RATS. Abstract [Details]
(1990) THE EFFECT OF TIANEPTINE ON THE OLFACTORY BULBECTOMIZED (OB) RAT MODEL OF DEPRESSION.
KELLY, JP,LEONARD, BE (1990) THE EFFECT OF TIANEPTINE ON THE OLFACTORY BULBECTOMIZED (OB) RAT MODEL OF DEPRESSION. Abstract [Details]

Correction

  Year Publication
(2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory regions (vol 19, pg A37, 2005).
Roche, M,Diamond, M,Lonergan, I,Keeney, G,Kelly, JP,Finn, DP (2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory regions (vol 19, pg A37, 2005). Correction [Details]

Meeting

  Year Publication
(2013) The antidepressant actions of captodiamine involve enhanced monoamine turnover in the frontal cortex and neurotrophic plasticity in the hypothalamus.
Ring, R,O'Brien, S,Kelly, JP,Regan, CM (2013) The antidepressant actions of captodiamine involve enhanced monoamine turnover in the frontal cortex and neurotrophic plasticity in the hypothalamus. Meeting [Details]
(2013) Behavioural effects of early life fluoxetine exposure in the rat.
O'Brien, S,Kelly, JP (2013) Behavioural effects of early life fluoxetine exposure in the rat. Meeting [Details]
(2011) EFFECTS OF PRENATAL METHAMPHETAMINE EXPOSURE ON NEURODEVELOPMENTAL AND SOMATIC TESTS IN THE NEONATAL RAT.
O'Brien, S,Fahy, GE,Campadieu, N,Kelly, JP (2011) EFFECTS OF PRENATAL METHAMPHETAMINE EXPOSURE ON NEURODEVELOPMENTAL AND SOMATIC TESTS IN THE NEONATAL RAT. Meeting [Details]
(2011) GENDER DIFFERENCES IN RAT BEHAVIOURAL RESPONSES TO AMPHETAMINE.
Simpson, J,Ryan, C,Kelly, JP (2011) GENDER DIFFERENCES IN RAT BEHAVIOURAL RESPONSES TO AMPHETAMINE. Meeting [Details]
(2008) Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats.
Roche, M,Kelly, JP,O'Driscoll, M,Finn, DP (2008) Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats. Meeting [Details]
(2005) Altered physiological responses to stress in the olfactory bulbectomised rat: normalisation by chronic fluoxetine treatment.
Roche, M,Harkin, A,Kelly, JP (2005) Altered physiological responses to stress in the olfactory bulbectomised rat: normalisation by chronic fluoxetine treatment. Meeting [Details]
(2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory cytokines in discrete rat brain regions.
Roche, M,Diamond, M,Lonergan, I,Keeney, G,Kelly, JP,Finn, DP (2005) The effects of acute lipopolysaccharide injection on levels of pro- and anti-inflammatory cytokines in discrete rat brain regions. Meeting [Details]
(2004) Methylenedioxymethamphetamine ('Ecstasy') suppresses neutrophil phagocytosis.
Connor, TJ,O'Shaughnessy, D,Kelly, JP (2004) Methylenedioxymethamphetamine ('Ecstasy') suppresses neutrophil phagocytosis. Meeting [Details]
(2002) Effect of a cyclodextrin-lofepramine complex on the motility of Tetrahymena pyriformis.
Darcy, P,Kelly, JP,Leonard, BE,Henry, JA (2002) Effect of a cyclodextrin-lofepramine complex on the motility of Tetrahymena pyriformis. Meeting [Details]

Note

  Year Publication
(1995) N-G-NITRO-L-ARGININE METHYL-ESTER PROTECTS AGAINST LIPID-PEROXIDATION IN THE GERBIL FOLLOWING CEREBRAL-ISCHEMIA.
CALDWELL, M;ONEILL, M;EARLEY, B;KELLY, JP;LEONARD, BE (1995) N-G-NITRO-L-ARGININE METHYL-ESTER PROTECTS AGAINST LIPID-PEROXIDATION IN THE GERBIL FOLLOWING CEREBRAL-ISCHEMIA. AMSTERDAM: ELSEVIER SCIENCE BV Note [Details]
(1995) THE EFFECT OF 2-AMINO-3-PHOSPHONOPROPIONIC ACID (AP-3) IN THE GERBIL MODEL OF CEREBRAL-ISCHEMIA.
MAGINN, M;CALDWELL, M;KELLY, JP;LEONARD, BE (1995) THE EFFECT OF 2-AMINO-3-PHOSPHONOPROPIONIC ACID (AP-3) IN THE GERBIL MODEL OF CEREBRAL-ISCHEMIA. AMSTERDAM: ELSEVIER SCIENCE BV Note [Details]
(1995) N-G-NITRO-L-ARGININE METHYL-ESTER PROTECTS AGAINST LIPID-PEROXIDATION IN THE GERBIL FOLLOWING CEREBRAL-ISCHEMIA.
CALDWELL, M,ONEILL, M,EARLEY, B,KELLY, JP,LEONARD, BE (1995) N-G-NITRO-L-ARGININE METHYL-ESTER PROTECTS AGAINST LIPID-PEROXIDATION IN THE GERBIL FOLLOWING CEREBRAL-ISCHEMIA. Note [Details]

Reviews

  Year Publication
(2020) Interventions for the management of obesity in people with bipolar disorder.
Tully, A;Smyth, S;Conway, Y;Geddes, J;Devane, D;Kelly, JP;Jordan, F (2020) Interventions for the management of obesity in people with bipolar disorder. HOBOKEN: WILEY Reviews [DOI] [Details]
(2020) Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia.
Jordan, F;Quinn, TJ;McGuinness, B;Passmore, P;Kelly, JP;Smith, CT;Murphy, K;Devane, D (2020) Aspirin and other non-steroidal anti-inflammatory drugs for the prevention of dementia. HOBOKEN: WILEY Reviews [DOI] [Details]
(2001) Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat.
O'Loinsigh, ED;Boland, G;Kelly, JP;O'Boyle, KM (2001) Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD Reviews [Details]
(2003) A review of the relevance and validity of olfactory bulbectomy as a model of depression.
Harkin, A;Kelly, JP;Leonard, BE (2003) A review of the relevance and validity of olfactory bulbectomy as a model of depression. OXFORD: ELSEVIER SCI LTD Reviews [DOI] [Details]
(2006) Immunomodulatory effects of caffeine: Friend or foe?.
Horrigan, LA;Kelly, JP;Connor, TJ (2006) Immunomodulatory effects of caffeine: Friend or foe?. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD Reviews [DOI] [Details]
(2007) Development of a home cage locomotor tracking system capable of detecting the stimulant and sedative properties of drugs in rats.
Dunne, F;O'Halloran, A;Kelly, JP (2007) Development of a home cage locomotor tracking system capable of detecting the stimulant and sedative properties of drugs in rats. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD Reviews [DOI] [Details]
(2011) The impact of environmental enrichment in laboratory rats-Behavioural and neurochemical aspects.
Simpson, J;Kelly, JP (2011) The impact of environmental enrichment in laboratory rats-Behavioural and neurochemical aspects. AMSTERDAM: ELSEVIER SCIENCE BV Reviews [DOI] [Details]
(2012) Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat.
Simpson, J;Bree, D;Kelly, JP (2012) Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD Reviews [DOI] [Details]
(2012) Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests.
Simpson, J;Ryan, C;Curley, A;Mulcaire, J;Kelly, JP (2012) Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD Reviews [DOI] [Details]
(2012) An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat.
Simpson, J;Kelly, JP (2012) An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat. AMSTERDAM: ELSEVIER SCIENCE BV Reviews [DOI] [Details]
(2017) The Role of Oxidative Stress in Methamphetamine-induced Toxicity and Sources of Variation in the Design of Animal Studies.
McDonnell-Dowling, K;Kelly, JP (2017) The Role of Oxidative Stress in Methamphetamine-induced Toxicity and Sources of Variation in the Design of Animal Studies. SHARJAH: BENTHAM SCIENCE PUBL LTD Reviews [DOI] [Details]
(1997) The olfactory bulbectomized rat as a model of depression: An update.
Kelly, JP;Wrynn, AS;Leonard, BE (1997) The olfactory bulbectomized rat as a model of depression: An update. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD Reviews [Details]
(2015) Sources of variation in the design of preclinical studies assessing the effects of amphetamine-type stimulants in pregnancy and lactation.
McDonnell-Dowling, K,Kelly, JP (2015) Sources of variation in the design of preclinical studies assessing the effects of amphetamine-type stimulants in pregnancy and lactation. Reviews [DOI] [Details]
(2012) An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat.
Simpson, J,Kelly, JP (2012) An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat. Reviews [DOI] [Details]
(2012) Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat.
Simpson, J,Bree, D,Kelly, JP (2012) Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat. Reviews [DOI] [Details]
(2012) Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests.
Simpson, J,Ryan, C,Curley, A,Mulcaire, J,Kelly, JP (2012) Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests. Reviews [DOI] [Details]
(2011) The impact of environmental enrichment in laboratory rats-Behavioural and neurochemical aspects.
Simpson, J,Kelly, JP (2011) The impact of environmental enrichment in laboratory rats-Behavioural and neurochemical aspects. Reviews [DOI] [Details]
(2007) Development of a home cage locomotor tracking system capable of detecting the stimulant and sedative properties of drugs in rats.
Dunne, F,O'Halloran, A,Kelly, JP (2007) Development of a home cage locomotor tracking system capable of detecting the stimulant and sedative properties of drugs in rats. Reviews [DOI] [Details]
(2003) A review of the relevance and validity of olfactory bulbectomy as a model of depression.
Harkin, A,Kelly, JP,Leonard, BE (2003) A review of the relevance and validity of olfactory bulbectomy as a model of depression. Reviews [DOI] [Details]
(2001) Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat.
O'Loinsigh, ED,Boland, G,Kelly, JP,O'Boyle, KM (2001) Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat. Reviews [Details]
(1997) The olfactory bulbectomized rat as a model of depression: An update. PHARMACOLOGY & THERAPEUTICS.
KELLY, JP et al. (1997) The olfactory bulbectomized rat as a model of depression: An update. PHARMACOLOGY & THERAPEUTICS. Reviews [Details]