Engineering

Dr Eimear Dolan

BE, PhD

Biography

Dr. Eimear Dolan was awarded her PhD in Biomedical Engineering from NUI Galway in 2015 for research in the field of orthopaedics under the supervision of Prof. Laoise McNamara. Prior to this, she graduated with a First Class Honours Degree in Biomedical Engineering from NUI Galway. Since graduating, she has worked as a postdoctoral researcher in Trinity College Dublin (TCD), Royal College of Surgeons (RCSI) and NUI Galway on European Union (EU) funded translational research programs, and Massachusetts Institute of Technology (MIT). As a postdoctoral researcher Dr Dolan has focused on the development and coupling of medical device systems with smart biomaterials and stem cells for the treatment of myocardial infarction and diabetes.
Dr. Dolan joined Biomedical Engineering at NUI Galway in September 2018 and became a Royal Society SFI University Research Fellow in 2019. Her key research interest is in medical devices, their effect on the host cells and coupling therapies to minimally invasive delivery devices. As an independent investigator, she is leveraging medical device innovations to enable biomaterial and cell/drug delivery, organ support and tissue engineering for various disease states.

Research Interests

Implantable soft robotic devices
https://www.nature.com/articles/s41467-022-32147-w
https://robotics.sciencemag.org/content/4/33/eaax7043.abstract
https://link.springer.com/article/10.1007/s10439-018-2046-2

Implantable drug/cell reservoirs
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202100820
https://www.sciencedirect.com/science/article/pii/S0928493118327838
https://link.springer.com/article/10.1007/s13346-019-00684-5
https://link.springer.com/article/10.1007/s13346-018-00601-2

Minimally invasive delivery devices
https://journals.sagepub.com/doi/full/10.1177/0885328218805878

Peer Reviewed Journals

	Year	Publication
	(2023)	'Soft robot¿mediated autonomous adaptation to fibrotic capsule formation for improved drug delivery' Rachel Beatty, Keegan L Mendez, Lucien HJ Schreiber, Ruth Tarpey, William Whyte, Yiling Fan, Scott T Robinson, Joanne O¿Dwyer, Andrew J Simpkin, Joseph Tannian, Peter Dockery, Eimear B Dolan, Ellen T Roche, Garry P Duffy (2023) 'Soft robot¿mediated autonomous adaptation to fibrotic capsule formation for improved drug delivery'. Science Robotics, [Details]
	(2024)	'Exploring therapy transport from implantable medical devices using experimentally informed computational methods' Lesley Trask, Niamh A. Ward, Ruth Tarpey, Rachel Beatty, Eimear Wallace, Joanne O'Dwyer, William Ronan, Garry P. Duffy and Eimear B. Dolan (2024) 'Exploring therapy transport from implantable medical devices using experimentally informed computational methods'. Biomaterials Science, [Details]
	(2024)	'Intermittent actuation attenuates fibrotic behaviour of myofibroblasts' Niamh A. Ward, Shirley Hanley, Ruth Tarpey, Lucien H.J. Schreiber, Joanne O'Dwyer, Ellen T. Roche, Garry P. Duffy, Eimear B. Dolan (2024) 'Intermittent actuation attenuates fibrotic behaviour of myofibroblasts'. Acta Biomateriala, [Details]
	(2019)	'Insulin-like growth factor-1 (IGF-1) poly (lactic-co-glycolic acid) (PLGA) microparticles - development, characterisation, and in vitro assessment of bioactivity for cardiac applications' Hameed A, Gallagher LB, Dolan E, O'Sullivan J, Ruiz-Hernandez E, Duffy GP, Kelly H. (2019) 'Insulin-like growth factor-1 (IGF-1) poly (lactic-co-glycolic acid) (PLGA) microparticles - development, characterisation, and in vitro assessment of bioactivity for cardiac applications'. Journal Of Microencapsulation, [DOI] [Details]
	(2021)	'The Foreign Body Response to an Implantable Therapeutic Reservoir in a Diabetic Rodent Model' Beatty, R., Lu, C., Marzi, J., Levey, R. E., Berrio, D. C., Lattanzi, G., Wylie, R., Connor, R. O., Wallace, E., Ghersi, G., Salamone, M., Dolan, E. B., Layland, S. L., Schenke-Layland, K., & Duffy, G. P. (2021) 'The Foreign Body Response to an Implantable Therapeutic Reservoir in a Diabetic Rodent Model'. Tissue Engineering, Part C: Methods, 27 (10):515-528 [DOI] [Details]
	(2022)	'Manufacturing, characterization, and degradation of a poly(lactic acid) warp-knitted spacer fabric scaffold as a candidate for tissue engineering applications' Caronna, F. and Glimpel, N. and Paar, G.-P. and Gries, T. and Blaeser, A. and Do, K. and Dolan, E.B. and Ronan, W. (2022) 'Manufacturing, characterization, and degradation of a poly(lactic acid) warp-knitted spacer fabric scaffold as a candidate for tissue engineering applications'. Biomaterials Science, 10 (14):3793-3807 [DOI] [Details]
	(2022)	'Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus' Domingo-Lopez, D. A., Lattanzi, G., Schreiber, L. H. J., Wallace, E. J., Wylie, R., O'Sullivan, J., Dolan, E. B., & Duffy, G. P. (2022) 'Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus'. Advanced Drug Delivery Reviews, 185 (114280):1-32 [DOI] [Details]
	(2022)	'Towards a whole sample imaging approach using diffusion tensor imaging to examine the foreign body response to medical devices' R. Levey, B. Tornifoglio, A.J. Stone, C. Kerskens, S.T. Robinson, F.B. Coulter, R. Bagnal, R. O¿Connor, E.B. Dolan, G. Bellavia, S. Straino, F. Cianfarani, P. Johnson, E. O¿Cearbhaill, C. Lally, G.P. Duffy (2022) 'Towards a whole sample imaging approach using diffusion tensor imaging to examine the foreign body response to medical devices'. Polymers, [Details]
	(2022)	'An implantable mechanotherapeutic platform for enhanced drug delivery' W. Whyte, D. Goswami, Y Fan, N.A. Ward, R.E. Levey, R. Beatty, S.T. Robinson, D. Sheppard, R. O¿Connor, L. Trask, D.S. Monahan, K.L. Mendez, C.E. Varela, M.A. Horvath, R. Wylie, J. O¿Dwyer, D.A. Domingo-Lopez, A.S. Rothman, G.P. Duffy (2022) 'An implantable mechanotherapeutic platform for enhanced drug delivery'. Nature Communications, [Details]
	(2022)	'Design and verification of a novel perfusion bioreactor to evaluate medical implants for peripheral artery applications' S. Nandan, J. Schiavi-Tritz, R. Helmut, C. Dunlop, ^T.J. Vaughan, ^E.B. Dolan (2022) 'Design and verification of a novel perfusion bioreactor to evaluate medical implants for peripheral artery applications'. Frontiers In Medicine, [Details]
	(2022)	'Manufacturing, characterization, and degradation of a poly (lactic acid) warp-knitted spacer fabric scaffold for tissue engineering applications' F. Coronna, N. Glimpel, G.Paar, T. Gries, A. Blaeser, Khoa Do, E.B. Dolan, ^W. Ronan (2022) 'Manufacturing, characterization, and degradation of a poly (lactic acid) warp-knitted spacer fabric scaffold for tissue engineering applications'. Biomaterials Science, [Details]
	(2022)	'Medical Devices, Smart Drug Delivery, Wearables and Technology for the treatment of Diabetes Mellitus' D.A. Domingo-Lopez, G. Lattanzi, L.H. J. Schreiber, E.J. Wallace, R. Wylie, J. O¿Sullivan, E.B. Dolan, G.P. Duffy (2022) 'Medical Devices, Smart Drug Delivery, Wearables and Technology for the treatment of Diabetes Mellitus'. Advanced Drug Delivery Reviews, [DOI] [Details]
	(2021)	'Assessing the effects of VEGF releasing microspheres on the angiogenic and foreign body response' .E Levey, F.B. Coulter, K.C. Scheiner, S. Deotti, S.T. Robinson, L. McDonough, T.T. Nguyen, R. Steendam, M. Canney, R. Wylie, L.P. Burke, E.B. Dolan, P. Dockery, H.M. Kelly, G. Ghersi, W.E. Hennink, R.J. Kok, E.D. O¿Cearbhaill, G.P. Duffy (2021) 'Assessing the effects of VEGF releasing microspheres on the angiogenic and foreign body response'. Pharmaceutics, [Details]
	(2021)	'A morphomics approach to understand the interplay between device design parameters and implant site' B. McDermott, S.R. Robinson, S. Holcombe, R. Levey, P. Dockery, P. Johnson S. Wang, ^E.B. Dolan, ^G.P. Duffy (2021) 'A morphomics approach to understand the interplay between device design parameters and implant site'. Journal Of The Royal Society Interface, [DOI] [Details]
	(2021)	'The foreign body response to an implantable therapeutic reservoir in a diabetic rodent model' R. Beatty, Chuan-en Lu, J. Marzi, R.E. Levey, D.A. Carvajal Berrio, G. Lattanzi, R. Wylie, R. O¿Connor, E. Wallace, E.B Dolan, S.L. Layland, K. Schenke-Layland, G.P Duffy (2021) 'The foreign body response to an implantable therapeutic reservoir in a diabetic rodent model'. Tissue Engineering, Part C: Methods, [DOI] [Details]
	(2021)	'Additive manufacturing of multi-scale porous soft tissue implants that encourage vascularisation and tissue ingrowth' F.B. Coulter, R.E. Levey, S.T. Robinson, S. Deotti, M. Monaghan, P. Dockery, E.B. Dolan, J. Prendergast, A.J Lowery, G. Bellavia, S. Straino, F. Cianfarani, M. Salamone, C.M. Bruno, G. Ghersi, G.P. Duffy, E. O Cearbhaill (2021) 'Additive manufacturing of multi-scale porous soft tissue implants that encourage vascularisation and tissue ingrowth'. Advanced Healthcare Materials*, [DOI] [Details]
	(2021)	'Design Considerations for Macroencapsulation Devices for Stem Cell Derived Islets for the Treatment of Type 1 Diabetes' D. Goswami, D.A. Domingo Lopez, N.A. Ward, J.R. Millman, G.P. Duffy^, E.B. Dolan^, E.T. Roche^ (2021) 'Design Considerations for Macroencapsulation Devices for Stem Cell Derived Islets for the Treatment of Type 1 Diabetes'. Advanced Science (Weinheim, Baden-Wurttemberg, Germany)*, [DOI] [Details]
	(2021)	'A Versatile Technique for High-Resolution 3D Imaging of Human Arterial Segments Using Micro-Computed Tomography' S.T. Robinson, R.E. Levey, R. Beatty, D. Connolly, E.B. Dolan, N.H. Osborne, P. Dockery, P.K. Henke, G.P. Duffy (2021) 'A Versatile Technique for High-Resolution 3D Imaging of Human Arterial Segments Using Micro-Computed Tomography'. Journal Of Vascular Surgery Cases And Innovative Techniques, [DOI] [Details]
	(2020)	'Pre-culture of Mesenchymal Stem Cells within RGD-modified Hyaluronic Acid Hydrogel Improves their Resilience to Ischaemic Conditions' Gallagher LB;Dolan EB;O'Sullivan J;Levey R;Cavanagh BL;Kovarova L;Pravda M;Velebny V;Farrell T;O'Brien FJ;Duffy GP; (2020) 'Pre-culture of Mesenchymal Stem Cells within RGD-modified Hyaluronic Acid Hydrogel Improves their Resilience to Ischaemic Conditions'. Acta Biomaterialia, [DOI] [ARAN Link] [Details]
	(2020)	'Enhancing Delivery of Small-Molecule- and Cell-Based Therapies for Ovarian Cancer Using Advanced Delivery Strategies' O'Dwyer, J;O'Cearbhaill, RE;Wylie, R;O'Mahony, S;O'Dwyer, M;Duffy, GP;Dolan, EB (2020) 'Enhancing Delivery of Small-Molecule- and Cell-Based Therapies for Ovarian Cancer Using Advanced Delivery Strategies'. Advanced Therapeutics, [DOI] [Details]
	(2020)	'Implantable Therapeutic Reservoir Systems for Diverse Clinical Applications in Large Animal Models' Duffy GP;Robinson ST;O'Connor R;Wylie R;Mauerhofer C;Bellavia G;Straino S;Cianfarani F;Mendez K;Beatty R;Levey R;O'Sullivan J;McDonough L;Kelly H;Roche ET;Dolan EB; (2020) 'Implantable Therapeutic Reservoir Systems for Diverse Clinical Applications in Large Animal Models'. Advanced Healthcare Materials, 9 (11) [DOI] [Details]
	(2019)	'Insulin-like growth factor-1 (IGF-1) poly (lactic-co-glycolic acid) (PLGA) microparticles - development, characterisation, and in vitro assessment of bioactivity for cardiac applications' Hameed, A;Gallagher, LB;Dolan, E;O'Sullivan, J;Ruiz-Hernandez, E;Duffy, GP;Kelly, H (2019) 'Insulin-like growth factor-1 (IGF-1) poly (lactic-co-glycolic acid) (PLGA) microparticles - development, characterisation, and in vitro assessment of bioactivity for cardiac applications'. Journal Of Microencapsulation, [DOI] [Details]
	(2019)	'Development of a nanomedicine-loaded hydrogel for sustained delivery of an angiogenic growth factor to the ischaemic myocardium' O'Dwyer, J,Murphy, R,Dolan, EB,Kovarova, L,Pravda, M,Velebny, V,Heise, A,Duffy, GP,Cryan, SA (2019) 'Development of a nanomedicine-loaded hydrogel for sustained delivery of an angiogenic growth factor to the ischaemic myocardium'. Drug Delivery And Translational Research, [DOI] [Details]
	(2019)	'A bioresorbable biomaterial carrier and passive stabilization device to improve heart function post-myocardial infarction' Dolan, EB;Hofmann, B;de Vaal, MH;Bellavia, G;Straino, S;Kovarova, L;Pravda, M;Velebny, V;Daro, D;Braun, N;Monahan, DS;Levey, RE;O'Neill, H;Hinderer, S;Greensmith, R;Monaghan, MG;Schenke-Layland, K;Dockery, P;Murphy, BP;Kelly, HM;Wildhirt, S;Duffy, GP (2019) 'A bioresorbable biomaterial carrier and passive stabilization device to improve heart function post-myocardial infarction'. Materials Science & Engineering C-Materials For Biological Applications, 103 [DOI] [Details]
	(2019)	'An actuatable soft reservoir modulates host foreign body response' E. B. Dolan, C. E. Varela, K. Mendez, W. Whyte, R. E. Levey, S. T. Robinson, E. Maye, J. O’Dwyer, R. Beatty, A. Rothman, Y. Fan, J. Hochstein, S. E. Rothenbucher, R. Wylie, J. R. Starr, M. Monaghan, P. Dockery, G. P. Duffy, E. T. Roche (2019) 'An actuatable soft reservoir modulates host foreign body response'. Science Robotics, [DOI] [ARAN Link] [Details]
	(2019)	'Insulin-like growth factor-1 (IGF-1) poly (lactic-co-glycolic acid) (PLGA) microparticles - development, characterisation, and in vitro assessment of bioactivity for cardiac applications' Hameed, A,Gallagher, LB,Dolan, E,O'Sullivan, J,Ruiz-Hernandez, E,Duffy, GP,Kelly, H (2019) 'Insulin-like growth factor-1 (IGF-1) poly (lactic-co-glycolic acid) (PLGA) microparticles - development, characterisation, and in vitro assessment of bioactivity for cardiac applications'. Journal Of Microencapsulation, [DOI] [Details]
	(2018)	'An injectable alginate/extra cellular matrix (ECM) hydrogel towards acellular treatment of heart failure' Clive J. Curley, Eimear B. Dolan, Matthias Otten, Svenja Hinderer, Garry P. Duffy, Bruce P. Murphy (2018) 'An injectable alginate/extra cellular matrix (ECM) hydrogel towards acellular treatment of heart failure'. Drug Delivery And Translational Research, [DOI] [Details]
	(2018)	'Advanced Material Catheter (AMCath), a minimally invasive endocardial catheter for the delivery of fast-gelling covalently cross-linked hyaluronic acid hydrogels' Eimear B Dolan, Lenka Kovarova, Hugh O'Neill, Martin Pravda Martin Pravda, Romana Sulakova, Ivana Scigalkova, Vladimir Velebny, Dorothee Daro, Nathalie Braun, Gerard M Cooney, Gabriella Bellavia, Stefania Straino, Brenton L Cavanagh, Aiden Flanagan, Helena M Kelly, Garry P Duffy, Bruce P Murphy (2018) 'Advanced Material Catheter (AMCath), a minimally invasive endocardial catheter for the delivery of fast-gelling covalently cross-linked hyaluronic acid hydrogels'. Journal Of Biomaterials Applications, [DOI] [Details]
	(2018)	'Hydrogels in adipose tissue engineering—Potential application in post‐mastectomy breast regeneration' Niamh A O'Halloran, Eimear B Dolan, Michael J Kerin, Aoife J Lowery, Garry P Duffy (2018) 'Hydrogels in adipose tissue engineering—Potential application in post‐mastectomy breast regeneration'. Journal Of Tissue Engineering And Regenerative Medicine, [DOI] [Details]
	(2018)	'Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart' Horvath, MA;Varela, CE;Dolan, EB;Whyte, W;Monahan, DS;Payne, CJ;Wamala, IA;Vasilyev, NV;Pigula, FA;Mooney, DJ;Walsh, CJ;Duffy, GP;Roche, ET (2018) 'Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart'. Annals Of Biomedical Engineering, 46 :1534-1547 [DOI] [Details]
	(2017)	'The development and mechanical characterisation of a novel reinforced venous conduit that mimics the mechanical properties of an arterial wall' Dolan, EB;Gunning, GM;Davis, TA;Cooney, G;Eufrasio, T;Murphy, BP (2017) 'The development and mechanical characterisation of a novel reinforced venous conduit that mimics the mechanical properties of an arterial wall'. Journal Of The Mechanical Behavior Of Biomedical Materials, 71 :23-31 [DOI] [Details]
	(2017)	'An in vitro investigation to assess procedure parameters for injecting therapeutic hydrogels into the myocardium' Curley, CJ;Dolan, EB;Cavanagh, B;O'Sullivan, J;Duffy, GP;Murphy, BP (2017) 'An in vitro investigation to assess procedure parameters for injecting therapeutic hydrogels into the myocardium'. Journal Of Biomedical Materials Research Part B-Applied Biomaterials, 105 :2618-2629 [DOI] [Details]
	(2017)	'A methylcellulose and collagen based temperature responsive hydrogel promotes encapsulated stem cell viability and proliferation in vitro' Payne, C;Dolan, EB;O'Sullivan, J;Cryan, SA;Kelly, HM (2017) 'A methylcellulose and collagen based temperature responsive hydrogel promotes encapsulated stem cell viability and proliferation in vitro'. Drug Delivery And Translational Research, 7 :132-146 [DOI] [Details]
	(2016)	'Biomaterial-Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives' O'Neill, HS;Gallagher, LB;O'Sullivan, J;Whyte, W;Curley, C;Dolan, E;Hameed, A;O'Dwyer, J;Payne, C;O'Reilly, D;Ruiz-Hernandez, E;Roche, ET;O'Brien, FJ;Cryan, SA;Kelly, H;Murphy, B;Duffy, GP (2016) 'Biomaterial-Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives'. Advanced Materials (Deerfield Beach, Fla.), 28 :5648-5661 [DOI] [Details]
	(2016)	'Thermally induced osteocyte damage initiates pro-osteoclastogenic gene expression in vivo' Dolan, EB;Tallon, D;Cheung, WY;Schaffler, MB;Kennedy, OD;McNamara, LM (2016) 'Thermally induced osteocyte damage initiates pro-osteoclastogenic gene expression in vivo'. Journal Of The Royal Society Interface, 13 [DOI] [Details]
	(2015)	'Mechanical Stimulation of Bone Marrow In Situ Induces Bone Formation in Trabecular Explants' Birmingham, E;Kreipke, TC;Dolan, EB;Coughlin, TR;Owens, P;McNamara, LM;Niebur, GL;McHugh, PE (2015) 'Mechanical Stimulation of Bone Marrow In Situ Induces Bone Formation in Trabecular Explants'. Annals Of Biomedical Engineering, 43 :1036-1050 [DOI] [Details]
	(2015)	'Thermally Induced Osteocyte Damage Initiates a Remodelling Signaling Cascade' Dolan, EB;Haugh, MG;Voisin, MC;Tallon, D;McNamara, LM (2015) 'Thermally Induced Osteocyte Damage Initiates a Remodelling Signaling Cascade'. Plos One, 10 [DOI] [Details]
	(2014)	'How Bone Tissue and Cells Experience Elevated Temperatures During Orthopaedic Cutting: An Experimental and Computational Investigation' Dolan, EB;Vaughan, TJ;Niebur, GL;Casey, C;Tallon, D;McNamara, LM (2014) 'How Bone Tissue and Cells Experience Elevated Temperatures During Orthopaedic Cutting: An Experimental and Computational Investigation'. Journal Of Biomechanical Engineering-Transactions Of The Asme, 136 [DOI] [Details]
	(2012)	'Heat-shock-induced cellular responses to temperature elevations occurring during orthopaedic cutting' Dolan, EB;Haugh, MG;Tallon, D;Casey, C;McNamara, LM (2012) 'Heat-shock-induced cellular responses to temperature elevations occurring during orthopaedic cutting'. Journal Of The Royal Society Interface, 9 :3503-3513 [DOI] [Details]

Book Chapters

	Year	Publication
	(2020)	'Cardiac Responses to Biomaterials' Joanne O’Dwyer, Robert Wylie, Sally Ann Cryan, Garry P Duffy, Eimear B. Dolan (2020) 'Cardiac Responses to Biomaterials' In: Handbook of Biomaterials Biocompatibility. United Kingdom: Woodhead Publishing Series in Biomaterials. [DOI] [Details]
	(2018)	'Chapter 1: Techniques for studying mechanobiology' Eimear B.Dolan, Stefaan W.Verbruggen, Rebecca A.Rolfe (2018) 'Chapter 1: Techniques for studying mechanobiology' In: Mechanobiology in Health and Disease. :1-53 Oxford, United Kingdom: Academic Press. [DOI] [Details]

Conference Publications

	Year	Publication
	(2020)	*26th Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland (BinI)* Wallace, E., Levey, R.E., Lattanzi G., Robinson S.T., Maye E., Beatty, R., O¿Dwyer, J., Dolan, E.B., Duffy, G.P. (2020) Assessing Macrophage Response to an Actuatable Soft Reservoir 26th Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland (BinI) [Details]
	(2011)	*14th Annual Sir Bernard Crosslands Symposium 2011* E.B Dolan, C Casey, L.M McNamara (2011) Experimental and Computational Analysis of Thermal Effects of Surgical Bone Cutting 14th Annual Sir Bernard Crosslands Symposium 2011 [Details]
	(2011)	*17th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2011* E.B Dolan^, C Casey, L.M McNamara (2011) Experimental and Computational Analysis of Thermal Effects of Surgical Bone Cutting 17th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2011 [Details]
	(2012)	*42nd International Sun Valley Workshop on Musculoskeletal Biology 2012* .B Dolan^, M.G Haugh, D Tallon, C Casey, L.M McNamara (2012) Heat-shock-induced Cellular Responses to Orthopaedic Cutting 42nd International Sun Valley Workshop on Musculoskeletal Biology 2012 [Details]
	(2012)	*15th Annual Sir Bernard Crosslands Symposium 2012* E.B Dolan^, M.G Haugh, D Tallon, C Casey, L.M McNamara (2012) Critical Times and Temperatures: Heat-Shock Induced Cellular Responses to Orthopaedic Cutting 15th Annual Sir Bernard Crosslands Symposium 2012 [Details]
	(2012)	*Orthopaedic Research Society Annual Meeting 2012* E.B Dolan, M.G Haugh, D Tallon, C Casey, L.M McNamara (2012) Heat-shock-induced Cellular Responses to Orthopaedic Cutting Orthopaedic Research Society Annual Meeting 2012 [Details]
	(2012)	*18th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2012* E.B Dolan^, M.G Haugh, D Tallon, C Casey, L.M McNamara , (2012) Heat-shock-induced Cellular Responses to Orthopaedic Cutting 18th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2012 [Details]
	(2013)	*Anatomical Society Annual Meeting 2013* E.B. Dolan^, M.G. Haugh L.M. McNamara (2013) Mild heat-shock of osteocytes enhances alkaline phosphatase activity and mineralization of untreated mesenchymal stem cells: A co-culture approach Anatomical Society Annual Meeting 2013 [Details]
	(2013)	*American Society of Mechanical Engineering 2013 Summer Bioengineering Conference 2013* E.B Dolan^, T.J Vaughan, G.L Niebur, D. Tallon, L.M McNamara, (2013) Understanding the Effects of Thermal Elevations associated with Orthopaedic Interventional: An Experimental and Computational Investigation American Society of Mechanical Engineering 2013 Summer Bioengineering Conference 2013 [Details]
	(2013)	*Orthopaedic Research Society Annual Meeting 2013* E.B Dolan, T.J Vaughan, G.L Niebur, D. Tallon, L.M McNamara (2013) Understanding the Effects of Thermal Elevations associated with Surgical Orthopaedic Cutting Orthopaedic Research Society Annual Meeting 2013 [Details]
	(2013)	*21th Annual Symposium on Computational Methods in Orthopaedic Biomechanics 2013* E.B Dolan^, T.J Vaughan, G.L Niebur, D. Tallon, L.M McNamara, (2013) Multi-scale Computational Investigation into Thermal Elevations Experienced by Osteocytes during Orthopedic Cutting Procedures 21th Annual Symposium on Computational Methods in Orthopaedic Biomechanics 2013 [Details]
	(2013)	*19th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2013* E.B Dolan^, T.J Vaughan, G.L Niebur, D. Tallon, L.M McNamara (2013) Investigation into Thermal Elevations Experienced by Osteocytes during Orthopaedic Procedures: An Experimental and Computational Analysis 19th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2013 [Details]
	(2014)	*2nd Annual Musculoskeletal Repair and Regeneration Symposium, Einstein, NY* E.B. Dolan^, Oran D. Kennedy, MG Haugh, Laoise M. McNamara. (2014) Thermally induced osteocyte apoptosis initiates osteoclastic and osteoblastic responses in vitro 2nd Annual Musculoskeletal Repair and Regeneration Symposium, Einstein, NY [Details]
	(2014)	*20th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2014* E.B. Dolan^, David Tallon, Oran D. Kennedy, WingYee Cheung, Mitchell B. Schaffler, Laoise M. McNamara. (2014) Thermally induced osteocyte apoptosis initiates osteoclastic and osteoblastic responses 20th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland 2014 [Details]
	(2014)	*Orthopaedic Research Society Annual Meeting 2014* E.B. Dolan, M.G. Haugh L.M. McNamara (2014) Thermally induced osteocyte apoptosis initiates octeoclastic and osteoblastic responses Orthopaedic Research Society Annual Meeting 2014 [Details]
	(2015)	*Orthopaedic Research Society Annual Meeting 2015* E.B. Dolan, D. Tallon, O.D. Kennedy, WingYee Cheung, M.B. Schaffler, L.M. McNamara. (2015) Osteocyte-driven responses to thermal elevations in vivo Orthopaedic Research Society Annual Meeting 2015 [Details]
	(2015)	*Orthopaedic Research Society Annual Meeting 2015* E.B. Dolan, D. Tallon, M Voisin, MG Haugh, L McNamara (2015) Thermally induced osteocyte apoptosis initiates pro-osteoclastic and pro-osteoblastic signaling responses Orthopaedic Research Society Annual Meeting 2015 [Details]
	(2015)	*TISSUE ENGINEERING PART A, vol. 21, pp. S212-S212. 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA: MARY ANN LIEBERT, INC, 2015* C.J Curley, E. B. Dolan, G. P. Duffy, B. P. Murphy. " (2015) Optimisation of Hydrogel Injection for Regeneration of Myocardial Infarction TISSUE ENGINEERING PART A, vol. 21, pp. S212-S212. 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA: MARY ANN LIEBERT, INC, 2015 [Details]
	(2017)	*Controlled Release Society Annual Meeting, 2017* L.B Gallagher, E.B Dolan, B. Cavanagh, J.O'Sullivan, H. O¿Neill, T.Farrell, F. O'Brien, G.P. Duffy (2017) Development of Functionalized Hydrogels to Enhance Stem Cell Therapy for Cardiac Regeneration Controlled Release Society Annual Meeting, 2017 [Details]
	(2017)	*Controlled Release Society Annual Meeting, 2017* E.B Dolan, H. Kelly, L. Kohutova, B. Kavanagh, D. Daro, B.P. Murphy, G.P. Duffy, (2017) Development of Hydrogel Carriers and Delivery Systems to Improve Cellular Retention for Cardiovascular Regeneration Controlled Release Society Annual Meeting, 2017 [Details]
	(2018)	*Controlled Release Society Annual Meeting, 2017* E.B Dolan, L. Kohutova, H. O¿Neill, B.L. Kavanagh, D. Daro, G. Cooney, H. Kelly, B.P. Murphy, G.P. Duffy, (2018) Design and development of a minimally invasive endocardial delivery device for fast-gelling hyaluronic acid hydrogels for the treatment of myocardial infarction Controlled Release Society Annual Meeting, 2017 [Details]
	(2018)	*World Congress of Biomechanics 2018* E.B. Dolan^, B. Hofmann, H. de Vaal, G. Bellavia, S. Straino, L. Kovarova, D. Monahan, H. Kelly S. Wildhirt, G.P. Duffy (2018) A Bioresorbable Biomaterial Carrier and Passive Stabilization Device to Improve Heart Function Post-Myocardial Infarction World Congress of Biomechanics 2018 [Details]
	(2018)	*World Congress of Biomechanics 2018* E.B. Dolan^, C.E. Varela, M. Horvath, W. Whyte, D. Monaghan, C.J. Payne, I.A. Wamala, N.V. Vasilyev, F.A. Pigula, D. J. Mooney, C.J. Walsh, G.P. Duffy, E.T. Roche (2018) Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart World Congress of Biomechanics 2018 [Details]
	(2018)	*Anatomical Society Meeting, Galway 2018* E.B. Dolan, L. Kohutova, H. O¿Neill, B.L. Kavanagh, D. Daro, G. Cooney, H.Kelly, B.P. Murphy, G.P. Duffy (2018) Design, development and pre-clinical assessment using a porcine model of a minimally invasive endocardial catheter for delivery of stem cells in fast-gelling hyaluronic acid hydrogels Anatomical Society Meeting, Galway 2018 [Details]
	(2018)	*BRITISH JOURNAL OF SURGERY, vol. 105, pp. 20-20. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY, 2018* N. O'Halloran, E.B Dolan, M. Kerin, G. Duffy, A. Lowery. (2018) Evaluation of a Cell-Seeded Hydrogel Scaffold as a Novel Adjunct to Implant Breast Reconstruction Post-Mastectomy BRITISH JOURNAL OF SURGERY, vol. 105, pp. 20-20. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY, 2018 [Details]
	(2018)	*Irish Journal of Medical Science, vol. 187, pp. S159-S159. 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND: SPRINGER LONDON LTD, 2018* N. O'Halloran, E. Gilligan, E.B Dolan, S. Khan, R. Dwyer, M. Kerin, G.P Duffy, A. Lowery. (2018) Evaluating a novel adipose tissue engineering strategy for breast reconstruction post-mastectomy Irish Journal of Medical Science, vol. 187, pp. S159-S159. 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND: SPRINGER LONDON LTD, 2018 [Details]
	(2019)	*Tissue Engineering and Regenerative Medicine International Society 2019* E.B. Dolan^, B. Hofmann, H. de Vaal, G. Bellavia, S. Straino, L. Kovarova, D. Monahan, H. Kelly S. Wildhirt, G.P. Duffy (2019) A Bioresorbable Biomaterial Carrier and Passive Stabilization Device to Improve Heart Function Post-Myocardial Infarction Tissue Engineering and Regenerative Medicine International Society 2019 [Details]
	(2019)	*25th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland* E.B. Dolan^, S Robinson, C Maurerhofer, R Beatty, R Levey, GP Duffy, (2019) Design of a therapeutic intraperitoneal reservoir system (THERIP) for regional, repeated drug delivery to the peritoneal space 25th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland [Details]
		*European Solid Mechanics Conference (ESMC) 2022* S. Nandan, J. Schiavi-Tritz, R. Helmut, C. Dunlop, ^T.J. Vaughan, ^E.B. Dolan 'Design and verification of a novel perfusion bioreactor to evaluate medical implants for peripheral artery applications European Solid Mechanics Conference (ESMC) 2022 [Details]
	(2022)	*European Solid Mechanics Conference (ESMC) 2022* F. Caronna, K. Do, W. Ronan, E.B. Dolan. (2022) In vitro investigation of the osteogenic properties of polylactide (PLA) and poly-4-hydroxybutyrate (P4HB) bioresorbable textile scaffolds European Solid Mechanics Conference (ESMC) 2022 [Details]
	(2022)	*European Solid Mechanics Conference (ESMC) 2022* R. Beatty, L.H.J Schreiber, K.L Mendez, W. Whyte, Y. Fan, S.T Robinson, E.T Roche, E.B Dolan, G.P Duffy. (2022) Soft robotic drug delivery devices to adapt to the foreign body response European Solid Mechanics Conference (ESMC) 2022 [Details]
	(2022)	*European Society of Biomaterials Annual Conference 2022* R. Beatty, L.H.J Schreiber, K.L Mendez, W. Whyte, Y. Fan, S.T Robinson, E.T Roche, E.B Dolan, G.P Duffy. (2022) Soft robotic drug delivery devices to adapt to the foreign body response European Society of Biomaterials Annual Conference 2022 [Details]
	(2019)	*Annals of Vascular Surgery 55 (2019): 30-31* S. Robinson, R.E Levey, E.B Dolan, D. Connolly, M. Chin, N.H. Osborne, P. Dockery, P.K. Henke, G.P. Duffy (2019) Virtual Histology of Human Arterial Wall Segments Using Microcomputed Tomography for Soft Tissue Imaging Annals of Vascular Surgery 55 (2019): 30-31 [Details]
	(2020)	*IRISH JOURNAL OF MEDICAL SCIENCE* R.S Challapalli, J. O'Dwyer, E.B Dolan, R. Dwyer, N ,McInerney, M.J. Kerin, G.P Duffy, A. Lowery (2020) Suitability of Hyaluronic Acid Hydrogels For Adipose Tissue Engineering IRISH JOURNAL OF MEDICAL SCIENCE [Details]
	(2020)	*In DIABETES TECHNOLOGY & THERAPEUTICS, vol. 22, pp. A192-A193. 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA: MARY ANN LIEBERT, INC, 2020* R.E Levey, F.B Coulter, S.T Robinson, S. Deotti, M. Monaghan, P. Dockery, E.B Dolan, E.D. O¿Cearbhaill, G.P. Duffy. (2020) Additive manufactured multiscale porous coatings on macroencapsulation devices modulate the host response In DIABETES TECHNOLOGY & THERAPEUTICS, vol. 22, pp. A192-A193. 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA: MARY ANN LIEBERT, INC, 2020 [Details]
	(2020)	*In DIABETES TECHNOLOGY & THERAPEUTICS, vol. 22, pp. A191-A191. 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA: MARY ANN LIEBERT, INC, 2020* R. Beatty, E.B Dolan, S.T. Robinson, R.E Levey, E. Maye, G.P Duffy, E.T Roche. (2020) An actuatable reservoir modulated host foreign body response In DIABETES TECHNOLOGY & THERAPEUTICS, vol. 22, pp. A191-A191. 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA: MARY ANN LIEBERT, INC, 2020 [Details]
	(2020)	*Diabetes 1 June 2020; 69 (Supplement_1): 1059¿P.¿* R.E Levey, F.B Coulter, S.T Robinson, L. McDonagh, S. Deotti, E.B Dolan, P. Dockery, H. Kelly, E.D. O¿Cearbhaill, G.P. Duffy (2020) 1059-P: Additive Manufactured Macroencapsulation Devices for Islet Cell Replacement Therapy Diabetes 1 June 2020; 69 (Supplement_1): 1059¿P.¿ [Details]
	(2020)	*Diabetes 1 June 2020; 69 (Supplement_1): 850¿P* R. Beatty, E.B Dolan, S.T. Robinson, R. O¿Connor, R. Wylie, G.P Duffy. (2020) 850-P: Continued Monitoring of the Foreign-Body Response to Improve Long-Term Success of Macroencapsulation Devices for Type 1 Diabetes: A Proof-of-Concept Study Diabetes 1 June 2020; 69 (Supplement_1): 850¿P [Details]
	(2020)	*EMTech MIT Technology Review Annual Conference* E.B. Dolan (2020) Improving the long-term performance of medical implants EMTech MIT Technology Review Annual Conference [Details]
	(2020)	*Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland, 2020* E. B. Dolan, C. E. Varela, K. Mendez, W. Whyte, R. E. Levey, S. T. Robinson, R. Beatty, M. Monaghan, E.T. Roche, G.P. Duffy (2020) An Actuatable Soft Reservoir Modulates Host Foreign Body Response Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland, 2020* [Details]
	(2022)	*Bioengineering in Ireland (Bini2022)* F. Caronna, K. Do, W. Ronan, E.B. Dolan. (2022) In vitro investigation of the osteogenic properties of polylactide (PLA) and poly-4-hydroxybutyrate (P4HB) bioresorbable textile scaffolds Bioengineering in Ireland (Bini2022) [Details]
	(2022)	*Bioengineering in Ireland (Bini2022)* L. Trask, G.P. Duffy, E.B. Dolan, (2022) Development of Islet-like Organoids of human origin for Type 1 Diabetes Bioengineering in Ireland (Bini2022) [Details]
	(2022)	*Bioengineering in Ireland (Bini2022)* A. Sheedy, A. Prakash, M. Gurney, M. O¿Dwyer, G.P Duffy, E.B. Dolan, (2022) Advanced immunotherapies and delivery strategies to treat ovarian cancer Bioengineering in Ireland (Bini2022) [Details]
	(2022)	*European Solid Mechanics Conference (ESMC) 2022* N.A. Ward, W. Whyte, D. Goswami, R.E. Levey, G.P. Duffy, E.T. Roche, E.B. Dolan (2022) Soft-Robotic Devices to Modulate the Host Foreign Body Response European Solid Mechanics Conference (ESMC) 2022 [Details]
	(2022)	*Summer Biomechanics, Bioengineering and Biotransport Conference 2022* N.A. Ward, W. Whyte, D. Goswami, R.E. Levey, G.P. Duffy, E.T. Roche, E.B. Dolan (2022) Mechanotherapeutics to modulate the foreign body response Summer Biomechanics, Bioengineering and Biotransport Conference 2022 [Details]
	(2022)	*Immune Modulation and Engineering Symposium* N.A. Ward, W. Whyte, D. Goswami, S.X. Wang, R.E. Levey, G.P. Duffy, E.T. Roche, E.B. Dolan (2022) Immunomodulation of the host foreign body response using cyclical pneumatic actuation Immune Modulation and Engineering Symposium [Details]
	(2022)	*European Association of Cancer Research (EACR) Annual Conference* A. Sheedy, A. Prakash, M. Gurney, M. O¿Dwyer, G.P Duffy, E.B. Dolan (2022) Cytotoxicity of Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-modified Natural Killer cells against ovarian cancer European Association of Cancer Research (EACR) Annual Conference [Details]
	(2022)	*World Congress of Biomechanics* W. Whyte, D. Goswami, S. Wang, Y. Fan, N.Ward, R.Levey, G. Duffy, E.B Dolan^, E. Roche. (2022) An implantable mechanotherapeutic platform for enhanced drug delivery World Congress of Biomechanics* [Details]
	(2022)	*European Solid Mechanics Conference* W.Whyte, D.Goswami, S. Wang, Y. Fan, C. Varela, G. Duffy, E.B Dolan^, E. Roche^. (2022) An implantable mechanotherapeutic platform to modulate the foreign body response European Solid Mechanics Conference* [Details]
	(2019)	*Annals of Vascular Surgery* S.T. Robinson, R. Levey, E.B. Dolan, D. Connolly, M. Chin, N.H. Osborne, P Dockery, P.K. Henke, G.P. Duffy. (2019) Virtual Histology of Human Arterial Wall Segments Using Microcomputed Tomography for Soft Tissue Imaging Annals of Vascular Surgery , pp.30-31 [Details]
	(2023)	*Bioengineering in Ireland (Bini2023)* Nandan, Swati and Simpson, H. and Clark, S. and Voustas, C. and Houston, G. and Bernini, M. and Dunlop, C. and Hellmuth, R. and Dolan, E.B. and Vaughan, T.J. (2023) Deformation of Self-Expanding Nitinol Stents Due to Limb-Flexion in Femoropopliteal Arteries of Thiel Embalmed Cadavers Bioengineering in Ireland (Bini2023) Enfield, Ireland, [Details]
	(2020)	*Suitability of Hyaluronic Acid Hydrogels For Adipose Tissue Engineering* Challapalli, RS,O'Dwyer, J,Dolan, E,Dwyer, R,McInerney, N,Kerin, MJ,Duffy, G,Lowery, A (2020) IRISH JOURNAL OF MEDICAL SCIENCE Suitability of Hyaluronic Acid Hydrogels For Adipose Tissue Engineering , pp.125-125 [Details]

Blog

	Year	Publication
	(2020)	Bringing Biomaterials to the Fore in Cell Therapy. J. O'Dwyer, E.B. Dolan (2020) Bringing Biomaterials to the Fore in Cell Therapy. Blog [Details]

Current Postgraduate Students (Research)

Student	Degree Type	Type
Aoibhín Sheedy	Doctorate - Structured Ph.D (Engineering)	Supervisor
Niamh Ward	Doctorate - Structured Ph.D (Engineering)	Supervisor
Flavia Caronna	Doctorate - PhD(Eng)	Co-supervisor (1)
Ritihaas Challapalli	Doctorate - Structured Ph.D (Medicine)	Co-supervisor (2)
Lesley Trask	Doctorate - Structured Ph.D (Engineering)	Supervisor
Swati Nandan	Doctorate - PhD(Eng)	Co-supervisor (1)
Parand Shokrani	Doctorate - Structured Ph.D (Engineering)	Supervisor

Internal Collaborators

	Name	Description of Collaboration
	Aoife Lowery
	William Ronan
	Ted Vaughan
	Prof Derek O'Keeffe	Formal collaborator on research funding

External Collaborators

Name	Organisation / Institute	Country	Description of Collaboration
Dr Melissa Geller	University of Minnesota	U.S.A.
Prof Ellen Roche	Massachusetts Institute Of Technology	U.S.A.
Prof Martin Felices	University of Minnesota	U.S.A.
Jeffrey Miller	University of Minnesota	U.S.A.
Prof Michael O'Dwyer	ONK Therapeutics and University of Galway	IRELAND	Research collaborator. Co-supervisor of PhD student
Jonathan McGuinness	Mater Hospital Dublin	IRELAND
Prof Garry Duffy	Anatomy, School of Medicine, NUI Galway	IRELAND