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Biological and Chemical Sciences
Dr Luca Ronconi
Contact Details
University of Galway
School of Biological and Chemical Sciences
University Road
Galway
E: luca.ronconi@universityofgalway.ie
Biography
Research Interests
Research Projects
Project | Start Date | End Date | |
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Federica Brescia - Gold(III)-glycoconjugates as antiviral agents against Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2): from rational design to biological evaluations | 01-SEP-21 | 31-AUG-25 | |
Rosy Polisicchio - Lanthanide-functionalized vitamin B12 probes for targeted tumor bio-imaging: from rational design to biological evaluation | 01-SEP-21 | 31-AUG-23 | |
Rosy Polisicchio - Lanthanide-functionalized vitamin B12 probes for targeted tumor bio-imaging: from rational design to biological evaluation | 01-SEP-19 | 31-AUG-21 | |
Rozan Mehder - Vitamin B12-functionalized metallodrugs for the targeted anticancer chemotherapy | 01-JAN-19 | 31-OCT-23 | |
IRC POSTGRADUATE SCHOLARSHIP 2018 - Ioannis Titilas - Metal-based glycoconjugates for the targeted anticancer chemotherapy | 01-OCT-18 | 30-SEP-22 | |
IRC POSTGRADUATE SCHOLARSHIP 2017 EIRINI FOTOPOULU - A ¿TWO BIRDS WITH ONE STONE¿ APPROACH TO THE TARGETED TREATMENT AND IMAGING OF TUMORS: VITAMIN B12-FUNCTIONALIZED METALLOTHERANOSTIC AGENTS | 01-OCT-17 | 30-SEP-20 | |
Eirini Fotopoulou - A "two birds with one stone" approach to the targeted treatment and imaging of tumors: vitamin B12-functionalized metallotheranostic agents | 01-SEP-16 | 30-SEP-17 | |
A "Trojan Horse" approach to the targeted anticancer chemotherapy: explitatin of tumor glycolysis by gold-glucose bioconjugates for the site-specific delivery of metal-based chemotherapeutics into tumor cells | 01-OCT-15 | 30-SEP-20 | |
Andrea Pettenuzzo - A "Trojan Horse" approach to the targeted anticancer chemotherapy: explitatin of tumor glycolysis by gold-glucose bioconjugates for the site-specific delivery of metal-based chemotherapeutics into tumor cells | 01-NOV-14 | 30-SEP-15 |
Peer Reviewed Journals
Year | Publication | |
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(2023) | 'Synthesis, characterisation, and in vitro cytotoxic activity of dithiocarbamato glycoconjugate half-sandwich ruthenium and osmium complexes'
J.J. Soldevila-Barreda, A. Pettenuzzo, M. Azmanova, L. Rafols, A.A.A. Attia, A. Lupan, L. Ronconi*, N.P.E. Barry, A. Pitto-Barry (2023) 'Synthesis, characterisation, and in vitro cytotoxic activity of dithiocarbamato glycoconjugate half-sandwich ruthenium and osmium complexes'. Helvetica Chimica Acta, 106 [DOI] [Details] |
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(2023) | 'Gold: not just jewelry¿'
F. Brescia, L. Ronconi* (2023) 'Gold: not just jewelry¿'. Future Medicinal Chemistry, 15 :647-650 [DOI] [Details] |
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(2022) | 'Metallodrugs as anticancer chemotherapeutics and diagnostic agents: a critical patent review (2010 - 2020)'
E. Fotopoulou, I. Titilas, L. Ronconi* (2022) 'Metallodrugs as anticancer chemotherapeutics and diagnostic agents: a critical patent review (2010 - 2020)'. Anticancer Research, 17 (1):42-54 [DOI] [Details] |
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(2021) | 'Metallodrug profiling against SARS-CoV-2 target proteins identifies highly potent inhibitors of the Spike/ACE2 interaction and the Papain-like Protease PLpro'
M. Gil-Moles, S. Türck, U. Basu, A. Pettenuzzo, S. Bhattacharya, A. Rajan, X. Ma, R. Büssing, J. Wölker, H. Burmeister, H. Hoffmeister, P. Schneeberg, A. Prause, P. Lippmann, J. Kusi-Nimarko, S. Hassell-Hart, A. McGown, D. Guest, Y. Lin, A. Notaro, R. Vinck, J. Karges, K. Cariou, K. Peng, X. Qin, X. Wang, J. Skiba, ¿. Szczupak, K. Kowalski, U. Schatzschneider, C. Hemmert, H. Gornitzka, E.R. Milaeva, A.A. Nazarov, G. Gasser, J. Spencer, L. Ronconi, U. Kortz, J. Cinatl, D. Bojkova, I. Ott (2021) 'Metallodrug profiling against SARS-CoV-2 target proteins identifies highly potent inhibitors of the Spike/ACE2 interaction and the Papain-like Protease PLpro'. Chem. Eur. J, 27 (71):17928-17940 [DOI] [Details] |
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(2021) | 'Design, physico-chemical characterization and in vitro biological activity of organogold(III) glycoconjugates'
A. Pettenuzzo, K. Vezzù, M.L. Di Paolo, E. Fotopoulou, L. Marchiò, L. Dalla Via, L. Ronconi* (2021) 'Design, physico-chemical characterization and in vitro biological activity of organogold(III) glycoconjugates'. Dalton Transactions, 50 :8963-8979 [DOI] [Details] |
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(2020) | 'Chimeric siRNA-DNA surfactants for the enhanced delivery and sustained cytotoxicity of a gold(III) metallodrug'
A.K. Hartmann, S. Gudipati, A. Pettenuzzo, L. Ronconi, J.L. Rouge (2020) 'Chimeric siRNA-DNA surfactants for the enhanced delivery and sustained cytotoxicity of a gold(III) metallodrug'. Bioconjugate Chemistry, 31 (4):1063-1069 [DOI] [Details] |
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(2019) | 'Stability of antibacterial Te(IV) compounds: a combined experimental and computational study'
K. D'Arcy, A.P. Doyle, K. Kavanagh, L. Ronconi, B. Fresch, D. Montagner (2019) 'Stability of antibacterial Te(IV) compounds: a combined experimental and computational study'. Journal Of Inorganic Biochemistry, 198 :110719-110719 [DOI] [Details] |
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(2018) | 'An innovative and efficient route to the synthesis of metal-based glycoconjugates: proof-of-concept and potential applications'
A. Pettenuzzo, D. Montagner, P. McArdle, L. Ronconi* (2018) 'An innovative and efficient route to the synthesis of metal-based glycoconjugates: proof-of-concept and potential applications'. Dalton Transactions, 47 :10721-10736 [DOI] [Details] |
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(2017) | 'Vitamin B12-metal conjugates for the targeted chemotherapy and diagnosis: current status and future prospects'
A. Pettenuzzo, R. Pigot, L. Ronconi* (2017) 'Vitamin B12-metal conjugates for the targeted chemotherapy and diagnosis: current status and future prospects'. European Journal Of Inorganic Chemistry, 12 :162-1638 [DOI] [Details] |
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(2014) | 'Preclinical activity of multiple-target gold(III)-dithiocarbamato peptidomimetics in prostate cancer cells and xenografts'
M. Celegato, D. Fregona, M. Mongiat, L. Ronconi, C. Borghese, V. Canzonieri, N. Casagrande, C. Nardon, A. Colombatti, D. Aldinucci (2014) 'Preclinical activity of multiple-target gold(III)-dithiocarbamato peptidomimetics in prostate cancer cells and xenografts'. Future Medicinal Chemistry, 6 :1249-1263 [DOI] [Details] |
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(2013) | 'Insights into the reactivity of gold-dithiocarbamato anticancer agents toward model biomolecules from multinuclear NMR spectroscopy'
G. Boscutti, L. Marchiò, L. Ronconi*, D. Fregona (2013) 'Insights into the reactivity of gold-dithiocarbamato anticancer agents toward model biomolecules from multinuclear NMR spectroscopy'. Chemistry - A European Journal, 19 :13428-13436 [DOI] [Details] |
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(2012) | 'Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3 / and Bax, leading to permeability transition pore opening and tumor cell death'
F. Chiara, A. Gambalunga, M. Sciacovelli, A. Nicolli, L. Ronconi, D. Fregona, P. Bernardi, A. Rasola, A. Trevisan (2012) 'Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3 / and Bax, leading to permeability transition pore opening and tumor cell death'. Cell Death & Disease, 3 :e444-e444 [DOI] [Details] |
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(2012) | 'Noble metal-dithiocarbamates: precious allies in the fight against cancer'
E.M. Nagy, L. Ronconi, C. Nardon, D. Fregona (2012) 'Noble metal-dithiocarbamates: precious allies in the fight against cancer'. Mini-Reviews In Medicinal Chemistry, 12 :1216-1229 [DOI] [Details] |
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(2012) | 't-Butylsarcosinedithiocarbamato gold(III)-based anticancer agents: design, in vitro biological evaluation and interaction with model biomolecules'
G. Boscutti, L. Feltrin, D. Lorenzon, S. Sitran, D. Aldinucci, L. Ronconi, D. Fregona (2012) 't-Butylsarcosinedithiocarbamato gold(III)-based anticancer agents: design, in vitro biological evaluation and interaction with model biomolecules'. Inorganica Chimica Acta, 393 :304-317 [DOI] [Details] |
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(2012) | 'Rational design of gold(III)-dithiocarbamato peptidomimetics for the targeted anticancer chemotherapy'
M. Negom Kouodom, G. Boscutti, M. Celegato, M. Crisma, S. Sitran, D. Aldinucci, F. Formaggio, L. Ronconi*, D. Fregona (2012) 'Rational design of gold(III)-dithiocarbamato peptidomimetics for the targeted anticancer chemotherapy'. Journal Of Inorganic Biochemistry, 117 :248-260 [DOI] [Details] |
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(2012) | 'Toward the selective delivery of chemotherapeutics into tumor cells by targeting peptide transporters: tailored gold-based anticancer peptidomimetics'
M. Negom Kouodom, L. Ronconi, M. Celegato, C. Nardon, L. Marchiò, Q.P. Dou, D. Aldinucci, F. Formaggio, D. Fregona (2012) 'Toward the selective delivery of chemotherapeutics into tumor cells by targeting peptide transporters: tailored gold-based anticancer peptidomimetics'. Journal Of Medicinal Chemistry, 55 :2212-2226 [DOI] [Details] |
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(2011) | 'Insights into the acid-base properties of PtIV-diazidodiam(m)inedihyroxido complexes from multinuclear NMR spectroscopy'
L. Ronconi, A.M. Pizarro, R.J. McQuitty, P.J. Sadler (2011) 'Insights into the acid-base properties of PtIV-diazidodiam(m)inedihyroxido complexes from multinuclear NMR spectroscopy'. Chemistry - A European Journal, 17 :12051-12058 [DOI] [Details] |
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(2011) | 'Gold(III)-dithiocarbamato anticancer agents: activity, toxicology and histopathological studies in rodents'
C. Marzano, L. Ronconi*, F. Chiara, M.C. Giron, I. Faustinelli, P. Cristofori, A. Trevisan, D. Fregona (2011) 'Gold(III)-dithiocarbamato anticancer agents: activity, toxicology and histopathological studies in rodents'. International Journal Of Cancer, 129 :487-496 [DOI] [Details] |
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(2011) | 'Antitumor activity of gold(III)-dithiocarbamato derivatives on prostate cancer cells and xenografts'
L. Cattaruzza, D. Fregona, M. Mongiat, L. Ronconi, A. Fassina, A. Colombatti, D. Aldinucci (2011) 'Antitumor activity of gold(III)-dithiocarbamato derivatives on prostate cancer cells and xenografts'. International Journal Of Cancer, 128 :206-215 [DOI] [Details] |
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(2011) | 'Photoreaction pathways for the anticancer complex trans,trans,trans-[Pt(N3)2(OH)2(NH3)2]'
L. Ronconi, P.J. Sadler (2011) 'Photoreaction pathways for the anticancer complex trans,trans,trans-[Pt(N3)2(OH)2(NH3)2]'. Dalton Transactions, 40 :262-268 [DOI] [Details] |
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(2010) | 'Recent advances in PUVA photochemotherapy and PDT for the treatment of cancer'
E.M. Nagy, L. Dalla Via, L. Ronconi, D. Fregona (2010) 'Recent advances in PUVA photochemotherapy and PDT for the treatment of cancer'. Current Pharmaceutical Design, 16 :1863-1876 [DOI] [Details] |
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(2010) | 'Latest insights into the anticancer activity of gold(III)-dithiocarbamato complexes'
L. Ronconi, D. Aldinucci, Q.P. Dou, D. Fregona (2010) 'Latest insights into the anticancer activity of gold(III)-dithiocarbamato complexes'. Anti-Cancer Agents in Medicinal Chemistry, 10 :283-292 [DOI] [Details] |
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(2010) | 'Inhibition of tumor proteasome activity by gold dithiocarbamato complexes via both redox-dependent and -independent processes'
X. Zhang, M. Frezza, V. Milacic, L. Ronconi, Y. Fan, C. Bi, D. Fregona, Q.P. Dou (2010) 'Inhibition of tumor proteasome activity by gold dithiocarbamato complexes via both redox-dependent and -independent processes'. Journal Of Cellular Biochemistry, 109 :162-172 [DOI] [Details] |
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(2009) | 'The Midas touch in cancer chemotherapy: from platinum- to gold-dothiocarbamato complexes'
L. Ronconi*, D. Fregona (2009) 'The Midas touch in cancer chemotherapy: from platinum- to gold-dothiocarbamato complexes'. Dalton Transactions, :10670-10680 [DOI] [Details] |
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(2009) | 'Groundbreaking gold(III) anticancer agents'
D. Aldinucci, L. Ronconi, D. Fregona (2009) 'Groundbreaking gold(III) anticancer agents'. Drug Discovery Today, 14 :1075-1076 [DOI] [Details] |
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(2009) | 'Preliminary chemico-biological studies on Ru(III) compounds with S-methylpyrrolidine/dimethyl dithiocarbamate'
L. Giovagnini, E. Mancinetti, L. Ronconi, S. Sitran, L. Marchiò, I. Castagliuolo, P. Brun, A. Trevisan, D. Fregona (2009) 'Preliminary chemico-biological studies on Ru(III) compounds with S-methylpyrrolidine/dimethyl dithiocarbamate'. Journal Of Inorganic Biochemistry, 103 :774-782 [DOI] [Details] |
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(2009) | 'Photoinduced reactions of cis,trans,cis-[PtIV(N3)2(OH)2(NH3)2] with 1-methylimidazole'
H.I.A. Phillips, L. Ronconi, P.J. Sadler (2009) 'Photoinduced reactions of cis,trans,cis-[PtIV(N3)2(OH)2(NH3)2] with 1-methylimidazole'. Chemistry - A European Journal, 15 :1588-1596 [DOI] [Details] |
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(2008) | 'Applications of heteronuclear NMR spectroscopy in biological and medicinal inorganic chemistry'
L. Ronconi, P.J. Sadler (2008) 'Applications of heteronuclear NMR spectroscopy in biological and medicinal inorganic chemistry'. Coordination Chemistry Reviews, 252 :2239-2277 [DOI] [Details] |
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(2008) | 'Unprecedented carbon-carbon bond formation induced by photoactivation of a platinum(IV)-diazido complex'
L. Ronconi, P.J. Sadler (2008) 'Unprecedented carbon-carbon bond formation induced by photoactivation of a platinum(IV)-diazido complex'. Chemical Communications, :235-237 [DOI] [Details] |
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(2007) | 'Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway'
D. Saggioro, M.P. Rigobello, L. Paloschi, A. Folda, S.A. Moggach, S. Parsons, L. Ronconi, D. Fregona, A. Bindoli (2007) 'Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway'. Chemistry & Biology, 14 :1128-1139 [DOI] [Details] |
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(2007) | 'Cationic carboxylato complexes of dirhodium(II) with oxo thioethers: catalysts for silane alcoholysis under homogeneous and liquid-liquid biphasic conditions'
A. Biffis, M. Basato, M. Brichese, L. Ronconi, C. Tubaro, A. Zanella, C. Graiff, A. Tiripicchio (2007) 'Cationic carboxylato complexes of dirhodium(II) with oxo thioethers: catalysts for silane alcoholysis under homogeneous and liquid-liquid biphasic conditions'. Advanced Synthesis & Catalysis, 349 :2485-2492 [DOI] [Details] |
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(2007) | 'Using coordination chemistry to design new medicines'
L. Ronconi, P.J. Sadler (2007) 'Using coordination chemistry to design new medicines'. Coordination Chemistry Reviews, 251 :1633-1648 [DOI] [Details] |
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(2007) | 'Formation of N-coordinated 4H-benzo[d][1,3]oxazine from 2-(trimethylsiloxymethyl)- and 2-(hydroxymethyl)-phenyl isocyanides promoted by dirhodium(II) acetate'
M. Basato, A. Biffis, G. Martinati, M. Polo, L. Ronconi, C. Tubaro, R. A. Michelin, P. Sgarbossa, S. Mazzega Sbovata (2007) 'Formation of N-coordinated 4H-benzo[d][1,3]oxazine from 2-(trimethylsiloxymethyl)- and 2-(hydroxymethyl)-phenyl isocyanides promoted by dirhodium(II) acetate'. Inorganic Chemistry Communications, 10 :407-409 [DOI] [Details] |
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(2006) | 'A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts'
V. Milacic, D. Chen, L. Ronconi, K.R. Landis-Piwowar, D. Fregona, Q.P. Dou (2006) 'A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts'. Cancer Research, 66 :10478-10486 [DOI] [Details] |
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(2006) | 'Insights into the mechanism of action of platinum anticancer drugs from multinuclear NMR spectroscopy'
S.J. Berners-Price, L. Ronconi, P.J. Sadler (2006) 'Insights into the mechanism of action of platinum anticancer drugs from multinuclear NMR spectroscopy'. Progress In Nuclear Magnetic Resonance Spectroscopy, 49 :65-98 [DOI] [Details] |
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(2006) | 'Gold(III) dithiocarbamate derivatives for the treatment of cancer: solution chemistry, DNA binding, and hemolytic properties'
L. Ronconi, C. Marzano, P. Zanello, M. Corsini, G. Miolo, C. Maccà, A. Trevisan, D. Fregona (2006) 'Gold(III) dithiocarbamate derivatives for the treatment of cancer: solution chemistry, DNA binding, and hemolytic properties'. Journal Of Medicinal Chemistry, 49 :1648-1657 [DOI] [Details] |
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(2005) | 'Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties and in vitro antitumor activity'
L. Ronconi, L. Giovagnini, C. Marzano, F. Bettio, R. Graziani, G. Pilloni, D. Fregona (2005) 'Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties and in vitro antitumor activity'. Inorganic Chemistry, 44 :1867-1881 [DOI] [Details] |
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(2005) | 'Synthesis, characterization and comparative in vitro cytotoxicity studies of platinum(II), palladium(II) and gold(III) methylsarcosinedithiocarbamate complexes'
L. Giovagnini, L. Ronconi, D. Aldinucci, D. Lorenzon, S. Sitran, D. Fregona (2005) 'Synthesis, characterization and comparative in vitro cytotoxicity studies of platinum(II), palladium(II) and gold(III) methylsarcosinedithiocarbamate complexes'. Journal Of Medicinal Chemistry, 48 :1588-1595 [DOI] [Details] |
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(2005) | 'Gold(III) dithiocarbamate derivatives of N-methylglycine: an experimental and theoretical investigation'
L. Ronconi, C. Maccato, D. Barreca, R. Saini, M. Zancato, D. Fregona (2005) 'Gold(III) dithiocarbamate derivatives of N-methylglycine: an experimental and theoretical investigation'. Polyhedron, 24 :521-531 [DOI] [Details] |
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(2004) | 'Organometallic complexes with biological molecules. XVIII. Alkyltin(IV) cephalexinate complexes: synthesis, solid state and solution phase investigations'
R. Di Stefano, M. Scopelliti, C. Pellerito, G. Casella, T. Fiore, G.C. Stocco, R. Vitturi, M. Colomba, L. Ronconi, I.D. Sciacca, L. Pellerito (2004) 'Organometallic complexes with biological molecules. XVIII. Alkyltin(IV) cephalexinate complexes: synthesis, solid state and solution phase investigations'. Journal Of Inorganic Biochemistry, 98 :534-546 [DOI] [Details] |
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(2003) | 'Pt(II) and Pd(II) derivatives of ter-butylsarcosinedithiocarbamate. Synthesis, chemical and biological characterization and in vitro nephrotoxicity'
D. Fregona, L. Giovagnini, L. Ronconi, C. Marzano, A. Trevisan, S. Sitran, B. Biondi, F. Bordin (2003) 'Pt(II) and Pd(II) derivatives of ter-butylsarcosinedithiocarbamate. Synthesis, chemical and biological characterization and in vitro nephrotoxicity'. Journal Of Inorganic Biochemistry, 93 :181-189 [DOI] [Details] |
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(2003) | 'Organotin(IV) complexes of ethylsarcosinehydrochloride: synthesis, characterization and in vitro anticancer activity'
L. Ronconi, C. Marzano, U. Russo, S. Sitran, R. Graziani, D. Fregona (2003) 'Organotin(IV) complexes of ethylsarcosinehydrochloride: synthesis, characterization and in vitro anticancer activity'. Applied Organometallic Chemistry, 17 :9-16 [DOI] [Details] |
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(2002) | 'Synthesis, characterization and in vitro cytotoxicity of new organotin(IV) derivatives of N-methylglycine'
L. Ronconi, C. Marzano, U. Russo, S. Sitran, R. Graziani, D. Fregona (2002) 'Synthesis, characterization and in vitro cytotoxicity of new organotin(IV) derivatives of N-methylglycine'. Journal Of Inorganic Biochemistry, 91 :413-420 [DOI] [Details] |
Book Chapters
Year | Publication | |
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(2018) | 'Application of heteronuclear NMR spectroscopy to bioinorganic and medicinal chemistry - 1st Currency Review'
E. Fotopoulou, L. Ronconi* (2018) 'Application of heteronuclear NMR spectroscopy to bioinorganic and medicinal chemistry - 1st Currency Review' In: Elsevier Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Waltham (MA): Elsevier. [DOI] [Details] |
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(2014) | 'Application of heteronuclear NMR spectroscopy to bioinorganic and medicinal chemistry'
D. Donghi, L. Ronconi* (2014) 'Application of heteronuclear NMR spectroscopy to bioinorganic and medicinal chemistry' In: Elsevier Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Waltham (MA): Elsevier. [Details] |
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(2013) | 'Perspective gold(III)-dithiocarbamato anticancer therapeutics: learning from the past, moving to the future'
L. Ronconi, C. Nardon, G. Boscutti, D. Fregona (2013) 'Perspective gold(III)-dithiocarbamato anticancer therapeutics: learning from the past, moving to the future' In: Advances in Anti-Cancer Agents in Medicinal Chemistry - Vol. 2. :130-172 Bussum: Bentham Science Publishers. [DOI] [Details] |
Other Journals
Year | Publication | |
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(2015) | 'Metal-based glycoconjugates and their potential in targeted anticancer chemotherapy'
A. Pettenuzzo, R. Pigot, L. Ronconi* (2015) 'Metal-based glycoconjugates and their potential in targeted anticancer chemotherapy' Metallodrugs, 1 :36-61. [DOI] [ARAN Link] [Details] |
Conference Contributions
Year | Publication | |
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(2023) | International Symposium on Bioorganometallic Chemistry 2023 - ISBOMC23,
R. Mehder, E. de la Torre-Rubio, E. Royo Cantabrana, L. Ronconi (2023) Vitamin B12-functionalized metallotheranostic agents for the targeted treatment and imaging of tumors. [Invited Oral Presentation], International Symposium on Bioorganometallic Chemistry 2023 - ISBOMC23, Braunschweig (Germany) , 18-SEP-23 - 21-SEP-23. [Details] |
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(2023) | 16th International Symposium on Applied Bioinorganic Chemistry - ISABC16,
I. Titilas, I. Romero-Canelon, M. Gil-Moles, I. Ott, L. Ronconi (2023) Metal-glycoconjugates for the targeted anticancer chemotherapy and their repurposing as antiviral agents against SARS-CoV-2. [Oral Presentation], 16th International Symposium on Applied Bioinorganic Chemistry - ISABC16, Ioannina (Greece) , 11-JUN-23 - 14-JUN-23. [Details] |
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(2022) | 3rd Medicinal Chemistry Ireland Conference,
L. Leahy, A. Dhara, E. Hever, K. Wojtzcak, F. Brescia, A. Smyth, S. Cacciapuoti, L. Ronconi, A. Erxleben, P. Murphy, E. Myers, Y. Ge (2022) Conference organization. [Conference Organising Committee Member], 3rd Medicinal Chemistry Ireland Conference, Galway (Ireland) , 17-JUN-22 - 17-JUN-22. [Details] |
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(2021) | Inorganic Ireland Symposium 2021,
A. Erxleben, C. Papatriantafyllopoulou, P. Farras, L. Ronconi, A. Ahmed, F. Dimakopoulou, N. Murphy, R. Polisicchio, M. Winterlich (2021) Conference organization. [Conference Organising Committee Member], Inorganic Ireland Symposium 2021, Galway (Ireland) , 14-MAY-21 - 14-MAY-21. [Details] |
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(2022) | 16th European Biological Inorganic Chemistry Conference - EUROBIC16,
A. Pettenuzzo, M. Gil-Moles, I. Ott, L. Ronconi (2022) Tale of a successful failure: gold(III)-glycoconjugates as antiviral agents against SARS-CoV-2. [Oral Presentation], 16th European Biological Inorganic Chemistry Conference - EUROBIC16, Grenoble (France) , 17-JUL-22 - 21-JUL-22. [Details] |
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(2022) | 3rd Medicinal Chemistry Ireland Conference,
A. Pettenuzzo, M. Gil-Moles, I. Ott, L. Ronconi (2022) Gold(III)-glycoconjugates as antiviral agents against SARS-CoV-2. [Invited Oral Presentation], 3rd Medicinal Chemistry Ireland Conference, Galway (Ireland) , 17-JUN-22 - 17-JUN-22. [Details] |
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(2021) | 5th Irish Biological Inorganic Chemistry Society Symposium - IBICS-5,
A. Pettenuzzo, I. Ott, L. Ronconi (2021) Tale of a successful failure: gold(III)-glycoconjugates as antiviral agents against SARS-CoV-2. [Keynote Address], 5th Irish Biological Inorganic Chemistry Society Symposium - IBICS-5, Maynooth (Ireland) , 26-NOV-21 - 26-NOV-21. [Details] |
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(2021) | Inorganic Ireland Symposium 2021,
A. Pettenuzzo, L. Dalla Via, L. Ronconi (2021) Gold-based dithiocarbamato glycoconjugates: a suitable strategy to target tumor glycolysis?. [Oral Presentation], Inorganic Ireland Symposium 2021, Galway (Ireland) , 14-MAY-21 - 14-MAY-21. [Details] |
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(2019) | 19th International Conference on Biological Inorganic Chemistry - ICBIC19,
A. Pettenuzzo, I. Ott, L. Dalla Via, L. Ronconi (2019) Metal-based dithiocarbamato glycoconjugates: a suitable strategy to target tumor glycolysis?. [Invited Oral Presentation], 19th International Conference on Biological Inorganic Chemistry - ICBIC19, Interlaken (Switzerland) , 11-AUG-19 - 16-AUG-19. [Details] |
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(2018) | 9th Asian Biological Inorganic Chemistry Conference - ASBIC9,
A. Pettenuzzo, E. Fotopoulu, L. Ronconi (2018) Gold: not just jewelry…. [Invited Oral Presentation], 9th Asian Biological Inorganic Chemistry Conference - ASBIC9, Singapore (Singapore) , 09-DEC-18 - 14-DEC-18. [Details] |
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(2018) | 2nd Irish Biological Inorganic Chemistry Society Symposium - IBICS-2,
L. Ronconi, P. Farras Costa, C. Papatriantafyllopoulou, C. Marmion (2018) Conference organization. [Conference Organising Committee Chairperson], 2nd Irish Biological Inorganic Chemistry Society Symposium - IBICS-2, Galway (Ireland) , 02-NOV-18 - 02-NOV-18. [Details] |
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(2018) | XIV International Symposium on Inorganic Biochemistry,
A. Pettenuzzo, E. Fotopoulu, L. Ronconi (2018) Gold: not just jewelry…. [Invited Oral Presentation], XIV International Symposium on Inorganic Biochemistry, Wrocław (Poland) , 05-OCT-18 - 08-OCT-18. [Details] |
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(2018) | 14th European Biological Inorganic Chemistry Conference - EUROBIC14,
A. Pettenuzzo, J. Wölker, I. Ott, L. Ronconi (2018) Gold-dithiocarbamato glycoconjugates for the targeted anticancer chemotherapy. [Invited Oral Presentation], 14th European Biological Inorganic Chemistry Conference - EUROBIC14, Birmingham (UK) , 26-AUG-18 - 30-AUG-18. [Details] |
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(2018) | RSC Dalton Division Meeting 2018,
A. Pettenuzzo, L. Ronconi (2018) A “sweet approach” to the targeted anticancer chemotherapy: gold-based glycoconjugates. [Oral Presentation], RSC Dalton Division Meeting 2018, Coventry (UK) , 03-APR-18 - 05-APR-18. [Details] |
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(2017) | 14th International Symposium on Applied Bioinorganic Chemistry - ISABC14,
A. Pettenuzzo, E. Fotopoulou, A. Terenzi, I. Ott, L. Ronconi (2017) Fancy a lift? Glucose and vitamin B12 as carriers for the targeted gold-based anticancer chemotherapy. [Oral Presentation], 14th International Symposium on Applied Bioinorganic Chemistry - ISABC14, Toulouse (France) , 07-JUN-17 - 10-JUN-17. [Details] |
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(2017) | Inorganic Ireland Symposium 2017,
A. Pettenuzzo, E. Fotopoulou, L. Ronconi (2017) Gold: not just jewelry…. [Oral Presentation], Inorganic Ireland Symposium 2017, Dublin (Ireland) , 16-MAY-17 - 16-MAY-17. [Details] |
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(2016) | 8th Asian Biological Inorganic Chemistry Conference - ASBIC8,
A. Pettenuzzo, I. Ott, L. Ronconi (2016) Gold(III)-based glycoconjugates for the targeted anticancer chemotherapy. [Invited Oral Presentation], 8th Asian Biological Inorganic Chemistry Conference - ASBIC8, Auckland (New Zealand) , 04-DEC-16 - 09-DEC-16. [Details] |
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(2016) | 13th European Biological Inorganic Chemistry Conference - EUROBIC13,
A. Pettenuzzo, L. Ronconi (2016) Metal-based glycoconjugates and their potential in targeted anticancer chemotherapy. [Oral Presentation], 13th European Biological Inorganic Chemistry Conference - EUROBIC13, Budapest (Hungary) , 28-AUG-16 - 01-SEP-16. [Details] |
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(2015) | 13th International Symposium of Applied Bioinorganic Chemistry - ISABC13,
A. Erxleben, D. Griffith, C. Marmion, D. Montagner, L. Ronconi (2015) Conference organization. [Conference Organising Committee Member], 13th International Symposium of Applied Bioinorganic Chemistry - ISABC13, Galway (Ireland) , 12-JUN-15 - 15-JUN-15. [Details] |
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(2014) | 12th European Biological Inorganic Chemistry Conference - EUROBIC12,
L. Ronconi (2014) Tailored gold-dithiocarbamato bioconjugates for the targeted anticancer chemotherapy. [Invited Oral Presentation], 12th European Biological Inorganic Chemistry Conference - EUROBIC12, Zurich (Switzerland) , 24-AUG-14 - 28-AUG-14. [Details] |
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(2014) | 2nd International Symposium on Functional Metal Complexes that Bind to Biomolecules - 3rd Whole Action Meeting COST Action CM1105,
R. Pigot, D. Goulding, L. Ronconi (2014) Conjugation of gold-based anticancer agents to tumor-targeting biomolecules: preliminary results and perspectives. [Oral Presentation], 2nd International Symposium on Functional Metal Complexes that Bind to Biomolecules - 3rd Whole Action Meeting COST Action CM1105, Zurich (Switzerland) , 22-AUG-14 - 23-AUG-14. [Details] |
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(2014) | 66th Irish Universities Chemistry Research Colloquium,
A. Erxleben, N. Geraghty, P. O'Leary, L. Ronconi, K. Kelly, D. McGrath (2014) Conference organization. [Conference Organising Committee Member], 66th Irish Universities Chemistry Research Colloquium, Galway (Ireland) , 19-JUN-14 - 20-JUN-14. [Details] |
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(2013) | 6th Meeting of the Irish Institute of Metal-Based Drugs - IIMBD_6,
R. Pigot, L. Ronconi (2013) Tailored gold(III)-dithiocarbamato complexes for the targeted anticancer chemotherapy. [Oral Presentation], 6th Meeting of the Irish Institute of Metal-Based Drugs - IIMBD_6, Dublin (Ireland) , 01-NOV-13 - 01-NOV-13. [Details] |
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(2013) | 1st International Symposium on Functional Metal Complexes that Bind to Biomolecules - 2nd Whole Action Meeting COST Action CM1105,
L. Ronconi (2013) Gold-based targeted chemotherapy: a statement of intent. [Oral Presentation], 1st International Symposium on Functional Metal Complexes that Bind to Biomolecules - 2nd Whole Action Meeting COST Action CM1105, Barcelona (Spain) , 09-SEP-13 - 10-SEP-13. [Details] |
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(2013) | XII International Symposium on Inorganic Biochemistry - Collaboration and Beyond,
G. Boscutti, L. Ronconi, D. Fregona (2013) Reactivity of gold-dithiocarbamato anticancer agents toward model biomolecules. [Oral Presentation], XII International Symposium on Inorganic Biochemistry - Collaboration and Beyond, Wrocław (Poland) , 28-AUG-13 - 01-SEP-13. [Details] |
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(2012) | 12th Workshop on PharmacoBioMetallics - BIOMET12,
D. Fregona, L. Dalla Via, L. Ronconi, M. Scopelliti, A. Dolmella, C. Marzano, C. Nardon, A. Adami, A. Pettenuzzo (2012) Conference organization. [Conference Organising Committee Member], 12th Workshop on PharmacoBioMetallics - BIOMET12, Padova (Italy) , 26-OCT-12 - 28-OCT-12. [Details] |
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(2012) | First Whole Action Meeting COST CM1105,
L. Ronconi, D. Fregona (2012) Tailored gold-based peptidomimetics for the targeted anticancer chemotherapy. [Oral Presentation], First Whole Action Meeting COST CM1105, Granada (Spain) , 17-SEP-12 - 18-SEP-12. [Details] |
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(2011) | 11th International Symposium on Applied Bioinorganic Chemistry - ISABC11,
L. Ronconi, D. Aldinucci, A. Trevisan, Q. P. Dou, F. Formaggio, D. Fregona (2011) Tailored gold-based anticancer peptidomimetics for the selective delivery into the tumor cell. [Oral Presentation], 11th International Symposium on Applied Bioinorganic Chemistry - ISABC11, Barcelona (Spain) , 02-DEC-11 - 05-DEC-11. [Details] |
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(2011) | Marie Curie Researchers Symposium SCIENCE - Passion, Mission, Responsibilities,
L. Ronconi (2011) Gold-based chemotherapy under way. [Invited Oral Presentation], Marie Curie Researchers Symposium SCIENCE - Passion, Mission, Responsibilities, Warsaw (Poland) , 25-SEP-11 - 27-SEP-11. [Details] |
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(2011) | Opening Ceremony of the Interdepartmental Research Center Role of Metal Ions in Biomedical Sciences - BIOMÉTION,
D. Fregona, P.M. Scrimin, L. Dalla Via, E.M. Nagy, L. Ronconi (2011) Conference organization. [Conference Organising Committee Member], Opening Ceremony of the Interdepartmental Research Center Role of Metal Ions in Biomedical Sciences - BIOMÉTION, Padova (Italy) , 01-JUN-11 - 01-JUN-11. [Details] |
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(2010) | 10th Workshop on Pharmaco-Bio-Metallics,
L. Ronconi, C. Marzano, F. Chiara, A. Trevisan, D. Fregona (2010) Latest insights into the anticancer activity of gold(III)-dithiocarbamato complexes. [Oral Presentation], 10th Workshop on Pharmaco-Bio-Metallics, Pozzuoli (NA) (Italy) , 29-OCT-10 - 30-OCT-10. [Details] |
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(2009) | 14th International Conference on Biological Inorganic Chemistry - 14th ICBIC,
L. Ronconi, M. Negom Kouodom, D. Aldinucci, Q.P. Dou, F. Formaggio, D. Fregona (2009) Gold(III)-based anticancer agents: peptide derivatives of sulfur donor ligands as improved intracellular drug transfer and delivery systems supported by transporter proteins. [Oral Presentation], 14th International Conference on Biological Inorganic Chemistry - 14th ICBIC, Nagoya (Japan) , 25-JUL-09 - 30-JUL-09. [Details] |
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(2006) | 9th International Symposium on Applied Bioinorganic Chemistry - 9th ISABC,
L. Ronconi, F.S. Mackay, J. Bella, P.J. Sadler (2006) Insights into photoreduction mechanisms for Pt(IV)-diazido anticancer agents from multinuclear NMR spectroscopy. [Oral Presentation], 9th International Symposium on Applied Bioinorganic Chemistry - 9th ISABC, Naples (Italy) , 02-DEC-06 - 05-DEC-06. [Details] |
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(2006) | XXXVII International Conference on Coordination Chemistry - 37th ICCC,
L. Ronconi, F.S. Mackay, J. Bella, P.J. Sadler (2006) Photoactivation pathways for platinum-diazido anticancer complexes. [Oral Presentation], XXXVII International Conference on Coordination Chemistry - 37th ICCC, Cape Town (South Africa) , 13-AUG-06 - 18-AUG-06. [Details] |
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(2005) | The 2005 Younger European Chemists’ Conference,
L. Ronconi, F.S. Mackay, J. Bella, P.J. Sadler (2005) Determination of pKa values of Pt(IV)-diamine anticancer complexes. [Oral Presentation], The 2005 Younger European Chemists’ Conference, Brno (Czech Republic) , 30-AUG-05 - 03-SEP-05. [Details] |
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(2005) | 16th Annual Conference - FORUM ENGELBERG 2005,
L. Ronconi, F.S. Mackay, P.J. Sadler (2005) Photoactivatable platinum(IV)-diazide complexes: a new generation of platinum-based anticancer agents. [Oral Presentation], 16th Annual Conference - FORUM ENGELBERG 2005, Engelberg (Switzerland) , 21-MAY-05 - 25-MAY-05. [Details] |
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(2004) | XXXII National Congress of the Inorganic Chemistry Division of the Italian Society of Chemistry,
L. Ronconi, C. Marzano, A. Trevisan, D. Fregona (2004) Innovative gold anticancer agents: design, chemical studies, and biological behavior. [Invited Oral Presentation], XXXII National Congress of the Inorganic Chemistry Division of the Italian Society of Chemistry, Rome (Italy) , 20-SEP-04 - 24-SEP-04. [Details] |
Honours and Awards
Year | Title | Awarding Body | |
---|---|---|---|
2019 | Nomination for a Research Supervisor Award (President’s Awards for Research Excellence) | National University of Ireland Galway, Galway (Ireland) | |
2006 | Special Prize in the section Application-Oriented Scientific Projects | 5a Edizione del Premio Regionale per l’Innovazione, Verona (Italy) | |
2005 | Award for the Best Multidisciplinary Project “SFP - Science For Patients” | 18th Workshop of Marie Curie Fellows: Research Training in Progress held under the 16th Annual Conference - FORUM ENGELBERG 2005, Engelberg (Switzerland) | |
2004 | Award for the Best Ph.D. Thesis in Inorganic Chemistry | Italian Society of Chemistry - Inorganic Chemistry Division at the XXXII Congresso Nazionale della Divisione di Chimica Inorganica della SCI, Rome (Italy) |
Professional Associations
Association | Function | From / To | |
---|---|---|---|
Royal Society of Chemistry - Republic of Ireland Local Section (RSC RoI LS) | Committee Member/Secretary (since 2020) | 19-AUG-19 / | |
Irish Biological Inorganic Chemistry Society (IBICS) | Member of the Standing Committee/Vice-President (2020-2023)/President (since January 2024) | 01-NOV-17 / | |
Society of Biological Inorganic Chemistry (SBIC) | Regular Member | 01-AUG-07 / | |
Royal Society of Chemistry (RSC) | Regular Member (MRSC) | 02-MAR-07 / | |
American Chemical Society (ACS) | Regular Member | 01-FEB-12 / 31-JAN-23 | |
Italian Society of Chemistry (SCI) | Regular Member | 01-JAN-03 / 31-DEC-12 |
Patents
Patent Number | Title | Granted | |
---|---|---|---|
WO2010105691A1 | Gold(III) complexes with oligopeptides functionalized with sulfur donors and use thereof as antitumor agents | 23-SEP-10 | |
IT1347835B1 | Dithiocarbamate complexes of gold(III) and their use as antitumor agents | 02-OCT-08 |
Committees
Committee | Function | From / To | |
---|---|---|---|
School of Biological and Chemical Sciences Infectious Diseases and One Health Section | Member | 01-SEP-22 / | |
School of Biological and Chemical Sciences Student Recruitment, Public Engagement and Internationalization Committee | Member | 01-SEP-22 / | |
GY301 - Bachelor of Science Degree Programme Board | Member | 01-JUN-21 / | |
University Student Complaint Panel | Member | 01-FEB-19 / | |
1st Year Chemistry Pathway | Coordinator | 22-MAR-16 / | |
BOC Postgraduate Award Committee | Chair | 01-NOV-14 / | |
School of Chemistry Staff-Students Committee | Member/Chair 2017-2022 | 01-SEP-17 / 31-AUG-22 | |
3rd Year Chemistry Teaching Committee | Chair | 01-AUG-17 / 31-AUG-22 | |
College of Science and Engineering Internationalization Committee | Chemistry Representative | 01-JUN-13 / 31-AUG-22 | |
School of Chemistry Workload Committee | Member | 03-JUN-16 / 31-AUG-21 |
Employment
Employer | Position | From / To | |
---|---|---|---|
University of Galway (Ireland) | Lecturer (Above the Bar) in Inorganic Chemistry | 01-SEP-21 / | |
National University of Ireland Galway (Ireland) | Lecturer (Below the Bar) in Inorganic Chemistry | 01-FEB-13 / 31-AUG-21 | |
University of Padova (Italy) | Assistant Professor of Inorganic Chemistry | 01-APR-08 / 27-JAN-13 | |
University of Padova (Italy) | Postdoctoral Fellow | 01-JAN-08 / 31-MAR-08 | |
University of Edinburgh (UK) | Körber Foundation Postdoctoral Fellow | 01-JAN-07 / 30-JUN-07 | |
University of Edinburgh (UK) | Marie Curie Intra-European Postdoctoral Fellow | 01-JAN-05 / 31-DEC-06 | |
University of Padova (Italy) | Postdoctoral Fellow | 01-NOV-03 / 31-OCT-04 |
Education
Year | Institution | Qualification | Subject | |
---|---|---|---|---|
2019 | National University of Ireland Galway | Postgraduate Certificate | Teaching and Learning in Higher Education | |
2004 | University of Padova (Italy) | PhD | Chemical Sciences | |
2002 | University of Padova (Italy) | MChem (Res) | Inorganic and Physical Chemistry |
Languages
Language | |
---|---|
Italian | |
English |
Reviews
Journal | Role | |
---|---|---|
Frontiers In Chemistry | Editoral Board | |
Molecules | Editoral Board | |
Angewandte Chemie - International Edition | Reviewer | |
Bioinorganic Chemistry And Applications | Reviewer | |
Chemical Research In Toxicology | Reviewer | |
Chemistry - A European Journal | Reviewer | |
Chemmedchem | Reviewer | |
Coordination Chemistry Reviews | Reviewer | |
Current Medicinal Chemistry | Reviewer | |
Dalton Transactions | Reviewer | |
European Journal Of Inorganic Chemistry | Reviewer | |
Inorganica Chimica Acta | Reviewer | |
Inorganic Chemistry | Reviewer | |
Journal Of Alzheimers Disease | Reviewer | |
Journal Of Biological Inorganic Chemistry | Reviewer | |
Journal Of Coordination Chemistry | Reviewer | |
Journal Of Inorganic Biochemistry | Reviewer | |
Journal Of Medicinal Chemistry | Reviewer | |
Letters In Drug Design & Discovery | Reviewer | |
Metal Ions In Biological Systems | Reviewer | |
New Journal Of Chemistry | Reviewer | |
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences | Reviewer | |
Plos One | Reviewer |
Other Activities
Description | |
---|---|
EXTERNAL BOARDS: PhD External Examiner (2014 - University of Warwick (UK); 2016 - University of Cape Town (South Africa); 2017 - University of Milan (Italy); 2019 - University of Warwick (UK); 2020 - Universidad de Alcalá (Spain); 2020 - University of Padova (Italy); 2021 - University of Pisa (Italy); 2023 - University of Birmingham (UK); 2024 - University of Parma (Italy)/ Expert International Evaluator (H2020-FETOPEN-2014-RIA; SONATA Funding Scheme 2015 (Poland); H2020-MSCA-IF-2015; H2020-MSCA-IF-2016; Czech Science Foundation Funding Scheme 2017 (Czech Republic); H2020-MSCA-IF-2017; H2020-MSCA-IF-2018; Leading Fellows Postdocs Programme 2018 (The Netherlands); H2020-MSCA-IF-2019; H2020-MSCA-IF-2020; H2020-MSCA-PF-2021; H2020-MSCA-PF-2022) |
Teaching Interests
Recent Postgraduate Students
Graduation | Name | Degree | Primary Supervisor | |
---|---|---|---|---|
2021 | Eirini Fotopoulou | PhD | Y | |
2023 | Ioannis Titilas | PhD | Y | |
2022 | Simona Cacciapuoti | Master of Chemistry (M.Chem.) | Y | |
2019 | Andrea Pettenuzzo | PhD | Y | |
2015 | Rebecca Pigot | Master of Chemistry (M.Chem.) | Y |
Current Postgraduate Students (Research)
Student | Degree Type | Type | |
---|---|---|---|
Rozan Mehder | Doctorate - Structured PhD (Science) | Supervisor | |
Federica Brescia | Doctorate - Structured PhD (Science) | Supervisor | |
Rosy Polisicchio | Doctorate - Structured PhD (Science) | Supervisor |
Modules Taught
Term/Year | Module Title | Module Code | Subject / Desc | |
---|---|---|---|---|
1st Year, Sem. I & II | Chemistry | CH101 | Atoms and the Periodic Table, Chemical Bonding, Quantitative Chemistry (Sem. I) / Chemical Reactions in Aqueous Solutions (Sem. II) | |
3rd Year, Sem. II | Inorganic Chemistry | CH307 | Introduction to Inorganic Chemistry Lab, Nuclear and Isotopic Chemistry | |
3rd Year, Sem. II | Computers in Chemical Research | CH3101 | Essays | |
3rd Year, Sem. II | Experimental Chemistry II | CH334 | Inorganic Practicals | |
4th Year, Sem. II | Current Topics in Medicinal Chemistry | CH4114 | Metal-Based Targeted Anticancer Chemotherapy | |
4th Year, Sem. I | Spectroscopic Methods & Applications | CH448 | Spectroscopy of Metal Complexes | |
PhD, Sem. II | Core Skills for Chemistry Research | CH506 | Spectroscopy of Coordination Compounds |
External Collaborators
Name | Organisation / Institute | Country | Description of Collaboration | |
---|---|---|---|---|
Prof. Zoe Pikramenou | University of Birmingham | UNITED KINGDOM | ||
Prof. Angela Casini | Technical University of Munich | GERMANY | ||
Prof. Orla Howe | Technological University Dublin | IRELAND | ||
Prof. Eva Royo Cantabrana | University of Alcalá | SPAIN | ||
Dr. Isolda Romero-Canelón | University of Birmingham | UNITED KINGDOM | ||
Prof. Lisa Dalla Via | University of Padova | ITALY | ||
Prof. Ingo Ott | Technical University Braunschweig | GERMANY | ||
Prof. Luciano Marchiò | University of Parma | ITALY |