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Prof Andrew Smyth

MB,BCh, BAO, MMedSc, PhD

 
researcher
 

Biography

Prof Smyth is Professor of Clinical Epidemiology at University of Galway and a Consultant Nephrologist at Galway University Hospitals. After graduating with a Bachelors in Medicine from University of Galway, he trained in Internal Medicine and Nephrology in Ireland, Mayo Clinic (Rochester, MN, USA) and McMaster University (Canada). He holds a MSc of Medical Science from University of Galway and a Structured PhD in Medicine / Clinical Epidemiology from University of Galway. He is the former Director of the HRB Clinical Research Facility Galway and MSc Clinical Research at University of Galway. Prof Smyth continues to teach on the MSc in Clinical Research Program in the School of Medicine at the University of Galway; he developed a number of modules in observational research, clinical trials, systematic reviews and meta-analysis and the ethics and regulatory frameworks for clinical research.

His research interests are in the epidemiology of chronic kidney disease, particularly modifiable risk factors for chronic kidney disease and the relationship between diet and health outcomes. He was the first Irish-based recipient of a Wellcome Trust Clinical Research Career Development Fellowship and collaborates closely with the Population Health Research Institute (PHRI) of McMaster University. He has published over 70 peer-review papers including first author publications in Lancet, Circulation and Kidney International, has >4300 citations and a H-index of 29. As part of his role as Director of HRB-CRFG, Prof Smyth was also a Director of Clinical Research Development Ireland, a Senior Management Team Member of HRB Clinical Research Coordination Ireland / National Clinical Trials Office and an Executive Committee member of the HRB Trials Research Methodology Network.

Research Interests

Nephrology, cardiovascular disease, epidemiology, clinical research methodology, clinical trials, observational studies, systematic reviews, meta-analysis.

Research Projects

  Project Start Date End Date
IDENTIFYING INTERVENTIONS TO PREVENT AND MANAGE CHRONIC KIDNEY DISEASE 01-SEP-16 31-AUG-18

Book Chapters

  Year Publication
(2017) 'Salt and Hypertension'
Smyth A, O'Donnell MJ (2017) 'Salt and Hypertension' In: Disorders of Blood Pressure Regulation: Phenotypes, Mechanisms, Therapeutic Options. New York: Springer International. [Details]
(2014) 'Autoimmune Kidney Disease and Pregnancy'
Smyth A, Stanhope TJ, White WM, Moder KG, Garovic VD (2014) 'Autoimmune Kidney Disease and Pregnancy' In: Encyclopedia of Medical Immunology. :124-132 New York: Springer-Verlag. [DOI] [Details]
(2014) 'Glomerular Disease in Pregnancy'
Smyth A, Garovic VD (2014) 'Glomerular Disease in Pregnancy' In: Core Concepts in Parenchymal Kidney Disease. New York: Springer-Verlag. [Details]

Peer Reviewed Journals

  Year Publication
(2020) 'Advance care plan barriers in older patients with end-stage renal disease: a qualitative nephrologist interview study'
O'Riordan, J,Noble, H,Kane, PM,Smyth, A (2020) 'Advance care plan barriers in older patients with end-stage renal disease: a qualitative nephrologist interview study'. Bmj Supportive & Palliative Care, 10 [DOI] [Details]
(2020) 'Advance care plan barriers in older patients with end-stage renal disease: a qualitative nephrologist interview study'
O'Riordan, J;Noble, H;Kane, PM;Smyth, A (2020) 'Advance care plan barriers in older patients with end-stage renal disease: a qualitative nephrologist interview study'. Bmj Supportive & Palliative Care, 10 [DOI] [Details]
(2019) 'Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study'
O'Donnell M and Mente A and Rangarajan S and McQueen MJ and O'Leary N and Yin L and Liu X and Swaminathan S and Khatib R and Rosengren A and Ferguson J and Smyth A and PURE Investigators (2019) 'Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study'. BMJ (Clinical research ed.), [DOI] [ARAN Link] [Details]
(2019) 'COSUTI: A protocol for the development of a core outcome set (COS) for interventions for the treatment of uncomplicated urinary tract infection (UTI) in adults'
Duane, S. and Vellinga, A. and Murphy, A.W. and Cormican, M. and Smyth, A. and Healy, P. and Moore, M. and Little, P. and Devane, D. (2019) 'COSUTI: A protocol for the development of a core outcome set (COS) for interventions for the treatment of uncomplicated urinary tract infection (UTI) in adults'. Trials, 20 (1) [DOI] [Details]
(2014) 'Vascular risk factors, cardiovascular disease and functional impairment in community-dwelling adults'
Canavan, M. and Glynn, L.G. and Smyth, A. and Mulkerrin, E.C. and Murphy, A.W. and Mulqueen, J. and McGrath, E.R. and O'Donnell, M.J. (2014) 'Vascular risk factors, cardiovascular disease and functional impairment in community-dwelling adults'. Gerontology, 60 (3):212-221 [DOI] [Details]
(2013) 'Mild chronic kidney disease and functional impairment in community-dwelling older adults'
Smyth, A. and Glynn, L.G. and Murphy, A.W. and Mulqueen, J. and Canavan, M. and Reddan, D.N. and O'Donnell, M. (2013) 'Mild chronic kidney disease and functional impairment in community-dwelling older adults'. Age and Ageing, 42 (4):488-494 [DOI] [Details]
(2019) 'COSUTI: a protocol for the development of a core outcome set (COS) for interventions for the treatment of uncomplicated urinary tract infection (UTI) in adults'
Duane, S,Vellinga, A,Murphy, AW,Cormican, M,Smyth, A,Healy, P,Moore, M,Little, P,Devane, D (2019) 'COSUTI: a protocol for the development of a core outcome set (COS) for interventions for the treatment of uncomplicated urinary tract infection (UTI) in adults'. Trials, 20 [DOI] [Details]
(2019) 'Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study'
O'Donnell, M;Mente, A;Rangarajan, S;McQueen, MJ;O'Leary, N;Yin, L;Liu, XY;Swaminathan, S;Khatib, R;Rosengren, A;Ferguson, J;Smyth, A;Lopez-Jaramillo, P;Diaz, R;Avezum, A;Lanas, F;Ismail, N;Yusoff, K;Dans, A;Iqbal, R;Szuba, A;Mohammadifard, N;Oguz, A;Yusufali, AH;Alhabib, KF;Kruger, IM;Yusuf, R;Chifamba, J;Yeates, K;Dagenais, G;Wielgosz, A;Lear, SA;Teo, K;Yusuf, S (2019) 'Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study'. Bmj-British Medical Journal, 364 [DOI] [Details]
(2019) 'Socioeconomic status and risk of cardiovascular disease in 20 low-income, middle-income, and high-income countries: the Prospective Urban Rural Epidemiologic (PURE) study'
Rosengren, A;Smyth, A;Rangarajan, S;Ramasundarahettige, C;Bangdiwala, SI;AlHabib, KF;Avezum, A;Bostrom, KB;Chifamba, J;Gulec, S;Gupta, R;Igumbor, EU;Iqbal, R;Ismail, N;Joseph, P;Kaur, M;Khatib, R;Kruger, IM;Lamelas, P;Lanas, F;Lear, SA;Li, W;Wang, CS;Quiang, D;Wang, Y;Lopez-Jaramillo, P;Mohammadifard, N;Mohan, V;Mony, PK;Poirier, P;Srilatha, S;Szuba, A;Teo, K;Wielgosz, A;Yeates, KE;Yusoff, K;Yusuf, R;Yusufali, AH;Attaei, MW;McKee, M;Yusuf, S (2019) 'Socioeconomic status and risk of cardiovascular disease in 20 low-income, middle-income, and high-income countries: the Prospective Urban Rural Epidemiologic (PURE) study'. Lancet Global Health, 7 :748-760 [DOI] [Details]
(2012) 'Page Kidney: Etiology, Renal Function Outcomes and Risk for Future Hypertension'
Smyth, A;Collins, CS;Thorsteinsdottir, B;Madsen, BE;Oliveira, GHM;Kane, G;Garovic, VD (2012) 'Page Kidney: Etiology, Renal Function Outcomes and Risk for Future Hypertension'. Journal Of Clinical Hypertension, 14 :216-221 [DOI] [Details]
(2012) 'Obstetric Nephrology: Lupus and Lupus Nephritis in Pregnancy'
Stanhope, TJ;White, WM;Moder, KG;Smyth, A;Garovic, VD (2012) 'Obstetric Nephrology: Lupus and Lupus Nephritis in Pregnancy'. Clinical Journal Of The American Society Of Nephrology, 7 :2089-2099 [DOI] [Details]
(2012) 'Maternal deaths in women with lupus nephritis: a review of published evidence'
Ritchie, J;Smyth, A;Tower, C;Helbert, M;Venning, M;Garovic, VD (2012) 'Maternal deaths in women with lupus nephritis: a review of published evidence'. Lupus, 21 :534-541 [DOI] [Details]
(2011) 'An audit of the impact of a stroke unit in an acute teaching hospital'
Lannon, R;Smyth, A;Mulkerrin, EC (2011) 'An audit of the impact of a stroke unit in an acute teaching hospital'. Irish Journal of Medical Science, 180 :37-40 [DOI] [Details]
(2017) 'Preeclampsia: a Cardiorenal Syndrome in Pregnancy'
Smyth, A.,Ronco, C.,Garovic, V. D. (2017) 'Preeclampsia: a Cardiorenal Syndrome in Pregnancy'. Current Hypertension Reports, 19 (22) [Details]
(2017) 'Response by Smyth et al to Letters Regarding Article, Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction: The INTERHEART Study'
Smyth, A.,O'Donnell, M.,Yusuf, S.,Interheart Investigators (2017) 'Response by Smyth et al to Letters Regarding Article, Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction: The INTERHEART Study'. Circulation, 135 (1010) [Details]
(2017) 'Effects of renal sympathetic denervation on blood pressure, sleep apnoea severity and metabolic indices: a prospective cohort study'
Daniels, F,De Freitas, S,Smyth, A,Garvey, J,Judge, C,Gilmartin, JJ,Sharif, F (2017) 'Effects of renal sympathetic denervation on blood pressure, sleep apnoea severity and metabolic indices: a prospective cohort study'. Sleep Medicine, 30 :180-184 [DOI] [Details]
(2017) 'Vitamin D deficiency and insufficiency prevalence in the west of Ireland-A retrospective study'
delos Reyes, J,Smyth, A,Griffin, D,O'Shea, P,O'Keeffe, S,Mulkerrin, EC (2017) 'Vitamin D deficiency and insufficiency prevalence in the west of Ireland-A retrospective study'. Journal Of Nutrition Health & Aging, 21 :1107-1110 [DOI] [Details]
(2017) 'Vitamin D deficiency and insufficiency prevalence in the west of Ireland - A retrospective study'
Delos Reyes J, Smyth A, Griffin D, O'Shea P, O'Keeffe ST, Mulkerrin EC (2017) 'Vitamin D deficiency and insufficiency prevalence in the west of Ireland - A retrospective study'. Journal Of Nutrition Health & Aging, [Details]
(2017) 'Two phosphAte taRGets in End-stage renal disease Trial (TARGET): A Randomized Controlled Trial'
Wald, R.,Rabbat, C. G.,Girard, L.,Garg, A. X.,Tennankore, K.,Tyrwhitt, J.,Smyth, A.,Rathe-Skafel, A.,Gao, P.,Mazzetti, A.,Bosch, J.,Yan, A. T.,Parfrey, P.,Manns, B. J.,Walsh, M. (2017) 'Two phosphAte taRGets in End-stage renal disease Trial (TARGET): A Randomized Controlled Trial'. Clinical Journal Of The American Society Of Nephrology, 12 (66):965-973 [Details]
(2017) 'Acute change in glomerular filtration rate with inhibition of the renin-angiotensin system does not predict subsequent renal and cardiovascular outcomes'
Clase, C. M.,Barzilay, J.,Gao, P.,Smyth, A.,Schmieder, R. E.,Tobe, S.,Teo, K. K.,Yusuf, S.,Mann, J. F. (2017) 'Acute change in glomerular filtration rate with inhibition of the renin-angiotensin system does not predict subsequent renal and cardiovascular outcomes'. Kidney International, 91 (33):683-690 [Details]
(2016) 'Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction: The INTERHEART Study'
Smyth, A,O'Donnell, M,Lamelas, P,Teo, K,Rangarajan, S,Yusuf, S,INTER-HEART Investigators (2016) 'Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction: The INTERHEART Study'. Circulation, 134 :1059-1067 [DOI] [Details]
(2016) 'Diet and Major Renal Outcomes: A Prospective Cohort Study. The NIH-AARP Diet and Health Study'
Smyth, A,Griffin, M,Yusuf, S,Mann, JFE,Reddan, D,Canavan, M,Newell, J,O'Donnell, M (2016) 'Diet and Major Renal Outcomes: A Prospective Cohort Study. The NIH-AARP Diet and Health Study'. Journal Of Renal Nutrition, 26 :288-298 [DOI] [Details]
(2016) 'VITAMIN D DEFICIENCY AND INSUFFICIENCY RATES IN THE WEST OF IRELAND: BETTER TARGETING OF AT RISK POPULATION REQUIRED?'
Delos Reyes, J,Smyth, A,O'Shea, P,Griffin, D,O'Keeffe, S,Mulkerrin, EC (2016) 'VITAMIN D DEFICIENCY AND INSUFFICIENCY RATES IN THE WEST OF IRELAND: BETTER TARGETING OF AT RISK POPULATION REQUIRED?'. Age And Ageing, 45 :14-14 [Details]
(2016) 'Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction: The INTERHEART Study'
Smyth, A.,O'Donnell, M.,Lamelas, P.,Teo, K.,Rangarajan, S.,Yusuf, S.,Interheart Investigators (2016) 'Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction: The INTERHEART Study'. Circulation, 134 (1515):1059-1067 [Details]
(2016) 'Diet and Major Renal Outcomes: A Prospective Cohort Study. The NIH-AARP Diet and Health Study'
Smyth, A.,Griffin, M.,Yusuf, S.,Mann, J. F.,Reddan, D.,Canavan, M.,Newell, J.,O'Donnell, M. (2016) 'Diet and Major Renal Outcomes: A Prospective Cohort Study. The NIH-AARP Diet and Health Study'. Journal Of Renal Nutrition, 26 (55):288-98 [Details]
(2016) 'Attitudes to outcomes measured in clinical trials of cardiovascular prevention'
Canavan, M.,Smyth, A.,Robinson, S. M.,Gibson, I.,Costello, C.,O'Keeffe, S. T.,Walsh, T.,Mulkerrin, E. C.,O'Donnell, M. J. (2016) 'Attitudes to outcomes measured in clinical trials of cardiovascular prevention'. QJM : monthly journal of the Association of Physicians, 109 (66):391-7 [Details]
(2016) 'An Approach to Optimise Therapeutic Vancomycin Dosage in a Haemodialysis Population'
Gunning, H.,Taylor, G.,Smyth, A.,Mellotte, G.,Fennell, J.,Murphy, P.,Lavin, P.,Wall, C. (2016) 'An Approach to Optimise Therapeutic Vancomycin Dosage in a Haemodialysis Population'. Irish Medical Journal, 109 (99) [Details]
(2016) 'Health system barriers and facilitators to medication adherence for the secondary prevention of cardiovascular disease: a systematic review'
Banerjee, A.,Khandelwal, S.,Nambiar, L.,Saxena, M.,Peck, V.,Moniruzzaman, M.,Faria Neto, J. R.,Quinto, K. C.,Smyth, A.,Leong, D.,Werba, J. P. (2016) 'Health system barriers and facilitators to medication adherence for the secondary prevention of cardiovascular disease: a systematic review'. Open Heartopen Heart, 3 (22) [Details]
(2016) 'Attitudes to outcomes measured in clinical trials of cardiovascular prevention'
Canavan, M,Smyth, A,Robinson, SM,Gibson, I,Costello, C,O'Keeffe, ST,Walsh, T,Mulkerrin, EC,O'Donnell, MJ (2016) 'Attitudes to outcomes measured in clinical trials of cardiovascular prevention'. Qjm-An International Journal Of Medicine, 109 :391-397 [DOI] [Details]
(2015) 'Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study'
Smyth, A,Teo, KK,Rangarajan, S,O'Donnell, M,Zhang, XH,Rana, P,Leong, DP,Dagenais, G,Seron, P,Rosengren, A,Schutte, AE,Lopez-Jaramillo, P,Oguz, A,Chifamba, J,Diaz, R,Lear, S,Avezum, A,Kumar, R,Mohan, V,Szuba, A,Wei, L,Yang, W,Jian, B,McKee, M,Yusuf, S,PURE Investigators (2015) 'Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study'. Lancet, 386 :1945-1954 [DOI] [Details]
(2015) 'Canadian Society of Nephrology commentary on the KDIGO clinical practice guideline for CKD evaluation and management'
Akbari, A.,Clase, C. M.,Acott, P.,Battistella, M.,Bello, A.,Feltmate, P.,Grill, A.,Karsanji, M.,Komenda, P.,Madore, F.,Manns, B. J.,Mahdavi, S.,Mustafa, R. A.,Smyth, A.,Welcher, E. S. (2015) 'Canadian Society of Nephrology commentary on the KDIGO clinical practice guideline for CKD evaluation and management'. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation, 65 (22):177-205 [Details]
(2015) 'Does Lowering Blood Pressure With Antihypertensive Therapy Preserve Independence in Activities of Daily Living? A Systematic Review'
Canavan, M,Smyth, A,Bosch, J,Jensen, M,McGrath, ER,Mulkerrin, EC,O'Donnell, MJ (2015) 'Does Lowering Blood Pressure With Antihypertensive Therapy Preserve Independence in Activities of Daily Living? A Systematic Review'. American Journal Of Hypertension, 28 :273-279 [DOI] [Details]
(2015) 'Healthy eating and reduced risk of cognitive decline A cohort from 40 countries'
Smyth, A,Dehghan, M,O'Donnell, M,Anderson, C,Teo, K,Gao, P,Sleight, P,Dagenais, G,Probstfield, JL,Mente, A,Yusuf, S,ONTARGET Investigator,TRANSCEND Investigator (2015) 'Healthy eating and reduced risk of cognitive decline A cohort from 40 countries'. Neurology, 84 :2258-2265 [DOI] [Details]
(2015) 'The Safety of Eplerenone in Hemodialysis Patients: A Noninferiority Randomized Controlled Trial'
Walsh, M.,Manns, B.,Garg, A. X.,Bueti, J.,Rabbat, C.,Smyth, A.,Tyrwhitt, J.,Bosch, J.,Gao, P.,Devereaux, P. J.,Wald, R. (2015) 'The Safety of Eplerenone in Hemodialysis Patients: A Noninferiority Randomized Controlled Trial'. Clinical Journal Of The American Society Of Nephrology, 10 (99):1602-8 [Details]
(2015) 'Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study'
Smyth, A.,Teo, K. K.,Rangarajan, S.,O'Donnell, M.,Zhang, X.,Rana, P.,Leong, D. P.,Dagenais, G.,Seron, P.,Rosengren, A.,Schutte, A. E.,Lopez-Jaramillo, P.,Oguz, A.,Chifamba, J.,Diaz, R.,Lear, S.,Avezum, A.,Kumar, R.,Mohan, V.,Szuba, A.,Wei, L.,Yang, W.,Jian, B.,McKee, M.,Yusuf, S.,Pure Investigators (2015) 'Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study'. Lancet, 386 (1000710007):1945-1954 [Details]
(2015) 'Dietary sodium and cardiovascular disease'
Smyth, A.,O'Donnell, M.,Mente, A.,Yusuf, S. (2015) 'Dietary sodium and cardiovascular disease'. Current Hypertension Reports, 17 (66) [Details]
(2015) 'Chronic kidney disease'
Clase, C. M.,Smyth, A. (2015) 'Chronic kidney disease'. Bmj Clinical Evidence, 2015 [Details]
(2015) 'Does lowering blood pressure with antihypertensive therapy preserve independence in activities of daily living? A systematic review'
Canavan, M.,Smyth, A.,Bosch, J.,Jensen, M.,McGrath, E. R.,Mulkerrin, E. C.,O'Donnell, M. J. (2015) 'Does lowering blood pressure with antihypertensive therapy preserve independence in activities of daily living? A systematic review'. American Journal Of Hypertension, 28 (22):273-9 [Details]
(2015) 'Dietary Sodium and Cardiovascular Disease'
Smyth, A,O'Donnell, M,Mente, A,Yusuf, S (2015) 'Dietary Sodium and Cardiovascular Disease'. Current Hypertension Reports, 17 [DOI] [Details]
(2014) 'Sodium Intake and Renal Outcomes: A Systematic Review'
Smyth, A,O'Donnell, MJ,Yusuf, S,Clase, CM,Teo, KK,Canavan, M,Reddan, DN,Mann, JFE (2014) 'Sodium Intake and Renal Outcomes: A Systematic Review'. American Journal Of Hypertension, 27 :1277-1284 [DOI] [Details]
(2014) 'The relationship between estimated sodium and potassium excretion and subsequent renal outcomes'
Smyth, A,Dunkler, D,Gao, P,Teo, KK,Yusuf, S,O'Donnell, MJ,Mann, JFE,Clase, CM,ONTARGET & TRANSCEND Investigators (2014) 'The relationship between estimated sodium and potassium excretion and subsequent renal outcomes'. Kidney International, 86 :1205-1212 [DOI] [Details]
(2014) 'Attitudes to Importance of Outcome Measures in Cardiovascular Prevention Trials'
Canavan M, Smyth A, Robinson S, Gibson I, Mulkerrin EC, O'Donnell M (2014) 'Attitudes to Importance of Outcome Measures in Cardiovascular Prevention Trials'. Irish Journal Of Medical Science, 193 :S329-S329 [Details]
(2014) 'Patterns of alcohol consumption and myocardial infarction risk: observations from 52 countries in the INTERHEART case-control study'
Leong DP, Smyth A, Teo KK, McKee M, Rangarajan S, Pais P, Liu L, Anand SS, Yusuf S; INTERHEART Investigators. (2014) 'Patterns of alcohol consumption and myocardial infarction risk: observations from 52 countries in the INTERHEART case-control study'. Circulation, 130 (5):390-398 [Details]
(2014) 'Vascular Risk Factors, Cardiovascular Disease and Functional Impairment in Community-Dwelling Adults'
Canavan, M,Glynn, LG,Smyth, A,Mulkerrin, EC,Murphy, AW,Mulqueen, J,McGrath, ER,O'Donnell, MJ (2014) 'Vascular Risk Factors, Cardiovascular Disease and Functional Impairment in Community-Dwelling Adults'. Gerontology, 60 :212-221 [DOI] [Details]
(2014) 'Acute change in GFR with inhibition of the renin-angiotensin system (RASI) as predictor of future renal and cardiovascular outcomes'
Mann JFE, Bazilay J, Gao P, Smyth A, Yusuf S, Teo KK, Clase CM (2014) 'Acute change in GFR with inhibition of the renin-angiotensin system (RASI) as predictor of future renal and cardiovascular outcomes'. Nephrology Dialysis Transplantation, [Details]
(2013) 'Salt intake and cardiovascular disease: why are the data inconsistent?'
O'Donnell, MJ,Mente, A,Smyth, A,Yusuf, S (2013) 'Salt intake and cardiovascular disease: why are the data inconsistent?'. European Heart Journal, 34 [DOI] [Details]
(2013) 'Mild chronic kidney disease and functional impairment in community-dwelling older adults'
Smyth, A,Glynn, LG,Murphy, AW,Mulqueen, J,Canavan, M,Reddan, DN,O'Donnell, M (2013) 'Mild chronic kidney disease and functional impairment in community-dwelling older adults'. Age And Ageing, 42 :488-494 [DOI] [Details]
(2013) 'Resting heart rate and decline in cognitive function: observations from the ONTARGET/TRANSCEND studie'
Leong DP, O'Donnell M, Teo KK, Smyth A, Joseph P, Gao P, Bohm MJ, Yusuf S (2013) 'Resting heart rate and decline in cognitive function: observations from the ONTARGET/TRANSCEND studie'. European Heart Journal, 34 [Details]
(2013) 'Women, kidney disease, and pregnancy'
Smyth A, Radovic M, Garovic VD (2013) 'Women, kidney disease, and pregnancy'. Advances In Chronic Kidney Disease, 20 (5):402-410 [Details]
(2013) 'The use of palliative care services amongst end-stage kidney disease patients in an Irish tertiary referral centre'
Redahan L, Brady B, Smyth A, Higgins S, Wall C (2013) 'The use of palliative care services amongst end-stage kidney disease patients in an Irish tertiary referral centre'. Nephrology Dialysis Transplantation, 6 (6):604-608 [Details]
(2013) 'Women, Kidney Disease, and Pregnancy'
Smyth, A,Radovic, M,Garovic, VD (2013) 'Women, Kidney Disease, and Pregnancy'. Advances In Chronic Kidney Disease, 20 :402-410 [DOI] [Details]
(2013) 'Effect of Blood Pressure Lowering Using Antihypertensive Drugs on Ability to Carry out Activities of Daily Living in Participants with Hypertension or Pre-Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials'
Canavan M, Smyth A, Jenson M, Robinson S, Mulkerrin EC, O'Donnell M (2013) 'Effect of Blood Pressure Lowering Using Antihypertensive Drugs on Ability to Carry out Activities of Daily Living in Participants with Hypertension or Pre-Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials'. Irish Journal Of Medical Science, 182 [Details]
(2013) 'An unusual presentation of MEN2A'
Casey R, Bell M, Keane M, Smyth A (2013) 'An unusual presentation of MEN2A'. Bmj Case Reports, [Details]
(2012) 'Peritoneal dialysis in an ageing population: A 10-year experience'
Smyth A, McCann E, Redahan L, Lambert B, Mellotte GJ, Wall C (2012) 'Peritoneal dialysis in an ageing population: A 10-year experience'. International Urology And Nephrology, 44 (1) [Details]
(2012) 'Page Kidney: Etiology, Renal Function Outcomes and Risk for Future Hypertension'
Smyth, A,Collins, CS,Thorsteinsdottir, B,Madsen, BE,Oliveira, GHM,Kane, G,Garovic, VD (2012) 'Page Kidney: Etiology, Renal Function Outcomes and Risk for Future Hypertension'. Journal Of Clinical Hypertension, 14 :216-221 [DOI] [Details]
(2012) 'Maternal deaths in women with lupus nephritis: a review of published evidence'
Ritchie, J,Smyth, A,Tower, C,Helbert, M,Venning, M,Garovic, VD (2012) 'Maternal deaths in women with lupus nephritis: a review of published evidence'. Lupus, 21 :534-541 [DOI] [Details]
(2012) 'Obstetric Nephrology: Lupus and Lupus Nephritis in Pregnancy'
Stanhope, TJ,White, WM,Moder, KG,Smyth, A,Garovic, VD (2012) 'Obstetric Nephrology: Lupus and Lupus Nephritis in Pregnancy'. Clinical Journal Of The American Society Of Nephrology, 7 :2089-2099 [DOI] [Details]
(2012) 'Closing the Audit Loop: Stroke Care in a University Hospital Three Years On'
Canavan M, Smyth A, Guilfoyle P, O'Brien J, Khan AZ, McGuinness B, O'Keeffe ST, O'Donnell M, Walsh T, Mulkerrin EC (2012) 'Closing the Audit Loop: Stroke Care in a University Hospital Three Years On'. Irish Journal Of Medical Science, 181 [Details]
(2011) 'An audit of the impact of a stroke unit in an acute teaching hospital'
Lannon, R,Smyth, A,Mulkerrin, EC (2011) 'An audit of the impact of a stroke unit in an acute teaching hospital'. Irish Journal Of Medical Science, 180 :37-40 [DOI] [Details]
(2010) 'Necrotising fasciitis of the shoulder in association with rheumatoid arthritis treated with etanercept: A case report'
Smyth A, Houlihan DD, Tuite H, Fleming C, O'Gorman T (2010) 'Necrotising fasciitis of the shoulder in association with rheumatoid arthritis treated with etanercept: A case report'. Clinical Case Reports, 4 (1) [Details]
(2010) 'Porphyria or not porphyria - that is the question'
Smyth A, Redahan L, Wall C, Mellotte GJ (2010) 'Porphyria or not porphyria - that is the question'. Bmj Case Reports, [Details]
(2010) 'An atypical pleural effusion'
Smyth A, Redahan L, Rahman T, Wall C, Mellotte GJ (2010) 'An atypical pleural effusion'. Bmj Case Reports, [Details]
(2010) 'A Systematic Review and Meta-Analysis of Pregnancy Outcomes in Patients with Systemic Lupus Erythematosus and Lupus Nephritis'
Smyth, A,Oliveira, GHM,Lahr, BD,Bailey, KR,Norby, SM,Garoyic, VD (2010) 'A Systematic Review and Meta-Analysis of Pregnancy Outcomes in Patients with Systemic Lupus Erythematosus and Lupus Nephritis'. Clinical Journal Of The American Society Of Nephrology, 5 :2060-2068 [Details]
(2010) 'Lifting the veil - a case of lobar atelectasis'
Salati U, Smyth A, Wall C (2010) 'Lifting the veil - a case of lobar atelectasis'. Bmj Case Reports, [Details]
(2009) 'Hypersensitivity to mesalazine in a patient with inflammatory bowel disease: A case report'
Cronin KC, Colleran C, Smyth A, Houlihan DD, O'Gorman T (2009) 'Hypersensitivity to mesalazine in a patient with inflammatory bowel disease: A case report'. Cases J, 2 (8) [Details]
(2009) 'Atypical cause of prolonged myelosuppression'
Smyth A, MacDonagh B, Tuite H, Fleming C, O'Dwyer ME (2009) 'Atypical cause of prolonged myelosuppression'. Bmj Case Reports, [Details]
(2009) 'An unusual cause of small bowel obstruction'
Houlihan DD, Smyth A, Sheehan S (2009) 'An unusual cause of small bowel obstruction'. Bmj Case Reports, [Details]
(2009) 'An unusual case of cavernous sinus syndrome'
Smyth, A.,Murphy, S.,Counihan, T. J. (2009) 'An unusual case of cavernous sinus syndrome'. Journal of Neurology, 256 [Details]
(2009) 'An unusual cause of cavernous sinus syndrome'
Smyth A, Murphy SM, Counihan TJ (2009) 'An unusual cause of cavernous sinus syndrome'. Bmj Case Reports, [Details]
(2009) '25 Year Old Man with Flank Pain, Hematuria and Proteinuria'
Smyth A, Garovic VD (2009) '25 Year Old Man with Flank Pain, Hematuria and Proteinuria'. Mayo Clinic Proceedings, 84 (1):72-75 [Details]

Conference Contributions

  Year Publication
(2016) Opportunistic Infections in Inflammatory Bowel Disease: Opportunity Gained or Lost?,
Harkin, G,Khan, R,Murray, A,Smyth, A,Keogh, A,Egan, L,Slattery, E (2016) IRISH JOURNAL OF MEDICAL SCIENCE. Opportunistic Infections in Inflammatory Bowel Disease: Opportunity Gained or Lost?, . [Details]
(2016) Vitamin D and Bone Health in Inflammatory Bowel Disease,
Harkin, G,Khan, R,Keogh, A,Murray, A,Smyth, A,Egan, L,Slattery, E (2016) IRISH JOURNAL OF MEDICAL SCIENCE. Vitamin D and Bone Health in Inflammatory Bowel Disease, . [Details]
(2014) Attitudes to Importance of Outcome Measures in Cardiovascular Prevention Trials,
Canavan, M,Smyth, A,Robinson, S,Gibson, I,Mulkerrin, E,O'Donnell, M (2014) IRISH JOURNAL OF MEDICAL SCIENCE. Attitudes to Importance of Outcome Measures in Cardiovascular Prevention Trials, . [Details]
Vascular Risk Factors and Functional Impairment in Community Dwelling Older Adults in the West of Ireland,
Canavan M, Smyth A, Mcgrath E, Glynn LG, Murphy AW, Mulkerrin EC, O'Donnell MJ -. [Conference Organising Committee Chairperson], Vascular Risk Factors and Functional Impairment in Community Dwelling Older Adults in the West of Ireland, - . [Details]
(2012) Closing the Audit Loop: Stroke Care in a University Hospital Three Years On,
Canavan, M,Smyth, A,Guilfoyle, P,O'Brien, H,Khan, A,McGuinness, B,O'Keeffe, S,O'Donnell, M,Walsh, T,Mulkerrin, E (2012) IRISH JOURNAL OF MEDICAL SCIENCE. Closing the Audit Loop: Stroke Care in a University Hospital Three Years On, . [Details]

Abstract

  Year Publication
(2009) An unusual case of cavernous sinus syndrome.
Smyth, A,Murphy, S,Counihan, TJ (2009) An unusual case of cavernous sinus syndrome. Abstract [Details]

Editorial

  Year Publication
(2018) When Less Is More: Optimizing Care for Elderly Patients Failing to Thrive on Dialysis.
O'Riordan, J,Kane, PM,Noble, H,Beatty, S,Mannion, E,Murtagh, C,Harnett, I,Smyth, A (2018) When Less Is More: Optimizing Care for Elderly Patients Failing to Thrive on Dialysis. Editorial [DOI] [Details]

Meeting

  Year Publication
(2013) Effect of Blood Pressure Lowering Using Antihypertensive Drugs on Ability to Carry out Activities of Daily Living in Participants with Hypertension or Pre-Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Canavan, M,Smyth, A,Jenson, M,Robinson, S,Mulkerrin, EC,O'Donnell, MJ (2013) Effect of Blood Pressure Lowering Using Antihypertensive Drugs on Ability to Carry out Activities of Daily Living in Participants with Hypertension or Pre-Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Meeting [Details]
(2012) Vascular Risk Factors and Functional Impairment in Community Dwelling Older Adults in the West of Ireland.
Canavan, M,Smyth, A,McGrath, E,Glynn, L,Murphy, A,Mulkerrin, E,O'Donnell, M (2012) Vascular Risk Factors and Functional Impairment in Community Dwelling Older Adults in the West of Ireland. Meeting [Details]

Reviews

  Year Publication
(2020) Adaptive design methods in dialysis clinical trials: a systematic review protocol.
Judge, C;Murphy, RP;Cormican, S;Smyth, A;O'Halloran, M;O'Donnell, M (2020) Adaptive design methods in dialysis clinical trials: a systematic review protocol. LONDON: BMJ PUBLISHING GROUP Reviews [DOI] [Details]
(2017) Preeclampsia: a Cardiorenal Syndrome in Pregnancy.
Smyth, A;Ronco, C;Garovic, VD (2017) Preeclampsia: a Cardiorenal Syndrome in Pregnancy. NEW YORK: SPRINGER Reviews [DOI] [Details]
(2014) Sodium Intake and Renal Outcomes: A Systematic Review.
Smyth, A;O'Donnell, MJ;Yusuf, S;Clase, CM;Teo, KK;Canavan, M;Reddan, DN;Mann, JFE (2014) Sodium Intake and Renal Outcomes: A Systematic Review. OXFORD: OXFORD UNIV PRESS Reviews [DOI] [Details]
(2013) Salt intake and cardiovascular disease: why are the data inconsistent?.
O'Donnell, MJ;Mente, A;Smyth, A;Yusuf, S (2013) Salt intake and cardiovascular disease: why are the data inconsistent?. OXFORD: OXFORD UNIV PRESS Reviews [DOI] [Details]
(2010) A Systematic Review and Meta-Analysis of Pregnancy Outcomes in Patients with Systemic Lupus Erythematosus and Lupus Nephritis.
Smyth, A;Oliveira, GHM;Lahr, BD;Bailey, KR;Norby, SM;Garoyic, VD (2010) A Systematic Review and Meta-Analysis of Pregnancy Outcomes in Patients with Systemic Lupus Erythematosus and Lupus Nephritis. WASHINGTON: AMER SOC NEPHROLOGY Reviews [Details]

Professional Associations

  Association Function From / To
Royal College of Physicians of Ireland Member /
International Society of Nephrology Member /
Irish Nephrology Society Member /
European Renal Association Member /
American Society of Nephrology Fellow /

Committees

  Committee Function From / To
HRB Trials Research Methodology Network Executive Committee Member 01-JAN-18 / 01-JUN-23
HRB National Clinical Trials Office Senior Management Team Member 01-JAN-21 / 01-JUN-23

Education

  Year Institution Qualification Subject
2006 University of Galway Bachelor of Medicine, Bachelor of Surger Medicine
2011 University of Galway MSc Medical Science
2015 University of Galway PhD Clinical Epidemiology / Medicine

Reviews

  Journal Role
Bmc Nephrology Editoral Board
American Journal Of Hypertension Reviewer
The Journal of rheumatology Reviewer
Kidney International Reviewer
Scientific Reports Reviewer
Bmj Case Reports Reviewer
BMJ Open Reviewer
Plos One Reviewer

Teaching Interests

Clinical research, epidemiology, clinical trials, systematic reviews, meta-analysis.

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
2015/2016 Cardiovascular Disease in Primary Care GNP05
2016-2020 Systematic Review Methods (5 ECTs) MD537
2015/2016 Foundations in Clinical Management MD313
2015-2020 Introduction to Research Methods for Randomised Controlled Trials MD538
2015/2016 Professionalism - Core Clinical Skills MD316
2015/2016 Advanced Clinical Diagnosis MD540
2015/2016 Advanced Clinical Theory MD542
2015/2016 Transitioning Programme MD543
2015 - Present Fundamentals of Health Research & Evaluation Methods MD510
2018/2019 Systematic Review Methods MD515
2017 - Present Systematic Review Methods (10 ECTs) MD515
2017 - Present Thesis (MSc Clinical Research) MD520
2016 - Present Introduction to Research Methods for Randomised Controlled Trials (10 ECTS version) MD514
2015/2016 Introduction to Medicine MD103

Internal Collaborators

  Name Description of Collaboration
Andrew Murphy
Martin O'Donnell
Declan Devane
Fidelma Dunne

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Salim Yusuf Population Health Research Institute CANADA
Catherine Clase McMaster University CANADA
Johannes Mann Munich GERMANY
Koon Teo Population Health Research Institute CANADA
Vesna Garovic Mayo Clinic U.S.A.
Michael Venning Manchester UNITED KINGDOM
Michael Walsh McMaster University CANADA