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Prof. Tim O'Brien

M.D, PH.D, MB.

 
researcher
 

Biography

Prof Tim O’Brien is a clinician scientist and practising physician and endocrinologist with an interest in treatment of diabetic complications using stem cell and gene therapy. He is Director of REMEDI and Head of the Department of Medicine at NUI Galway. He also directs the GMP facility in Galway which has recently been licensed for production of human MSCs and is PI on a clinical trial using MSCs in patients with no-option critical limb ischemia.

Research Interests

Prof Tim O’Brien is a clinician scientist and practising physician and endocrinologist with an interest in treatment of diabetic complications using stem cell and gene therapy. He is Director of REMEDI and Head of the Department of Medicine at NUI Galway. He also directs the GMP facility in Galway which has recently been licensed for production of human MSCs and is PI on a clinical trial using MSCs in patients with no-option critical limb ischemia.

Research Projects

  Project Start Date End Date
Medically licenced mesenchymal stem cells for the treatment of systemic sepsis 01-FEB-16 31-JUL-19
CURAM SPOKE MEDICAL ENERGETICS 3 of 3 - Tim O' Brien 01-FEB-16 31-JAN-19
CURAM SPOKE MEDICAL ENERGETICS 1 of 3 - Tim O' Brien 01-FEB-16 30-JUN-17
Assessment of a nebulised cell based therapy product for Acute Respiratory Distress Syndrome 01-JAN-16 31-DEC-16
BioLogy UndErluing diabeteS and its complicaTions: reseArch and tRaining - H2020 Proposal Prep Tim O' Brien 05-NOV-15 04-AUG-16
The in Vitro Biocompatibility of MCS's with the appropriate Boston Scientific proprietary devices 01-NOV-15 31-DEC-16
CURAM Platform Tim O'Brien 01-JUN-15 31-DEC-20
NEPHSTROM- Novel Stromal Cell Therapy for Diabetic Kidney Disease 01-MAY-15 30-NOV-19
NEPHSTROM- Novel Stromal Cell Therapy for Diabetic Kidney Disease 01-MAY-15 30-APR-19
NEPHSTROM FUNDS Account 01-MAY-15 30-APR-19
Paul Loftus IRC Employment Based Postrgraduate Programme Timothy O Brien 01-FEB-15 31-JAN-19
Paul Loftus IRC Employment Based Orbsen Therapeutics PG Programme Timothy O Brien 01-FEB-15 31-JAN-19
Therapeutic and Commercial Viability of Medically Licensed Mesenchymal Stem Cells for Acute Respiratory Distess Syndrome 01-JAN-15 31-AUG-16
CURAM SPOKE MEDICAL ENERGETICS 2 of 3 - Tim O' Brien 01-JAN-15 31-DEC-20
ME Coil Research in Diabetic Lower Extremity Ulceration 01-NOV-14 31-MAY-16
MSCs Boston - not set up in 2014 01-NOV-14 15-DEC-14
EI Innovatin Partnership - Lifewave 01-NOV-14 31-MAY-16
SCAFFOLD MEDIATED STEM CELL DELIVERY TIM O BRIEN 01-OCT-14 31-DEC-18
REGENERATIVE PROGRAM COLLEGE MED 01-AUG-14 28-FEB-22
WELLCOME TRUST SUMMER SCHOLARSHIP PROGRAMME CMNHS TIM O BRIEN 01-JUN-14 31-AUG-14
HRB SUMMER SCHOLARSHIPS 2014 TIMOTHY O BRIEN 01-MAY-14 20-DEC-15
HRB SFI TRANSLATIONAL RESEARCH AWARD FUNDING TIM O BRIEN 01-MAY-14 30-JUN-19
CCMI TIM O BRIEN GUF 14-APR-14 31-DEC-20
REPAIR OF DIABETIC DAMAGE BY STORMAL CELL ADMINISTRATION II TIM O BRIEN 15-JAN-14 14-OCT-15
DEVELOPMENT OF A REGULATORY COMPLIANT CELL PRODUCT FOR ACUTE RESPIRATORY DISTRESS SYNDROME D O TOOLE 01-JAN-14 30-AUG-16
REDDSTAR COLLABORATORS ACCOUNT 01-NOV-12 31-OCT-16
REDSSTAR EU PROJECT HEALTH F2 TIM O BRIEN RE7526 01-NOV-12 30-OCT-17
SFI REGENERATIVE MEDICINE CLINICAL TRIALS 09 SRC B1794 STTF 11 TIMOTHY O BRIEN 01-JAN-12 31-DEC-13
GMP FACILITY VARIOUS INTERNAL FUNDING 2012 ON 01-JAN-12 31-MAR-13
EI FP7 SUPPORT REDDSTAR TRAVEL SUPPORT CS 2011 482 TIMOTHY O BRIEN 24-NOV-11 24-JUL-12
DEAN Account Richard Flavin RSF STRAT INI Summer Studentships in the five Colleges 01-APR-11 31-DEC-20
ULYSSES TRAVEL SCHEME IRCSET TIM O BRIEN ULY 2011 19 07-MAR-11 08-JUN-12
ADVANCING MED HEA PRTLI5 TIM O'BRIEN 01-MAR-11 30-NOV-17
ESI HEA PRTLI5 BME & RMPETER MCHUGH ARUN THIRUMARAN 01-MAR-11 31-DEC-16
TRANSLATING SCIENCE TO SURGERY MSC AND GENE THERAPY IN CARTILAGE REPAIR HRB TIM O BRIEN HRB NAT SPR/SR ACADEMIC FLLSHP PROG NSAFP/2009/1 CATHAL MORAN 07-OCT-10 30-JUN-16
REMED1 2 Work Package 3 01-JUL-10 30-SEP-15
MEDTRONIC REMEDI CONTRIBUTION TIMOTHY O BRIEN 01-JUL-10 30-JUN-15
REMEDI-2 SRC From Research to Human Therapy 01-JUL-10 30-SEP-18
REMEDI 2 - Work Package 6 01-JUL-10 30-SEP-15
REMEDI 2 SRC -WP 1 01-JUL-10 30-SEP-18
REMEDI 2 SRC -Centre Management WP 01-JUL-10 03-SEP-18
REMEDI 2 Work Package 5 01-JUL-10 30-SEP-15
EI TRAVEL CS/2010/275 TIMOTHY O'BRIEN 20-MAY-10 31-JAN-11
HRB NSAFP 2009 3 PROF TIMOTHY O'BRIEN CONALL DENNEDY 01-JAN-10 30-NOV-13
FAMRI GALWAY UNIVERSITY FOUNDATION CORRADO SANTOCANALE 01-DEC-09 31-DEC-16
REMEDI MEDTRONIC PARTNERSHIP 2009 TIM O'BRIEN 01-JAN-09 31-DEC-10
REMEDI VPR INTERIM FUNDING - T O'BRIEN 01-JAN-09 31-DEC-19
REMEDI CSET SUPPLEMENT - 08/CE/B1436 01-JAN-09 30-JUN-11
DEBATING SCIENCE ISSUES 08 09 087084Z08Z T OBRIEN 01-OCT-08 31-AUG-10
07/SK/B1233b STOKES PROFESSORSHIP - PROF T OBRIEN 01-SEP-08 31-AUG-13
OIP 2008 GMP Maintenance 10-JUN-08 30-SEP-09
UNDERSTANDING THE BIOLOGY AND THERAPEUTIC APPLICAT 01-MAR-08 31-OCT-08
STOKES PROFESSORSHIP PROGRAMME 01-MAR-08 28-FEB-13
WELCOME TRUST 083987/Z/07/Z- AWARD DSI OBRIEN/KYNE 01-OCT-07 31-DEC-10
IRCSET EMBARK PHD - MIESZKO WILK REMEDI 01-OCT-07 30-SEP-12
GENETIC ENGINEERING OF VEIN GRAFTS TIMOTHY O'BRIEN REMEDI 01-OCT-07 30-SEP-11
EI CFTD 2007 105 LIPOSTENT T O BRIEN 01-SEP-07 31-JAN-10
READY SET BIO DONATION TIMOTHY OBRIEN 01-APR-07 31-DEC-18
ASTRA-ZENECADONATION AIDAN FLYNN T O'BRIEN 01-MAR-07 31-DEC-11
OIP 2007 EQUIP MAINTENANCE GMP TIM O'BRIEN 01-JAN-07 31-DEC-07
OIP 2007 EQUIP MAINTENANCE TIM O'BRIEN 01-JAN-07 31-DEC-07
HRB RP 2006 285 A O DOHERTY O BRIEN 01-OCT-06 30-JUL-09
IRCSET ALLESSIA STOCCA T OBRIEN REMEDI 01-OCT-06 14-DEC-09
EI CFTD 2006 111 IDSTEM REMEDI 01-SEP-06 31-DEC-08
HRB CRT 2004 24 RHR452 EXPRES EPC'S AARON LIEW 01-JUL-06 25-APR-08
RHEUMATOLOGY CARDIOLOGY POST DOCS T O BRIEN 19-APR-06 31-DEC-10
SFI OIP 2006 BIOINFORMATIONS SUPPORT T O BRIEN 01-JAN-06 31-DEC-06
REMEDI CHARGES NON VATABLE T O BRIEN 01-NOV-05 31-DEC-18
METRONIC ESSAY O BRIEN 01-OCT-05 31-DEC-09
SFI WALTON WINDEBANK 01-AUG-05 31-JUL-06
HRB CRT 2005 26 PROF T O BRIEN 01-JUL-05 30-JUN-07
SFI STAR IMELDA NOLAN 05 03 CE B312 STAR 05 T OBRI 01-JUN-05 31-AUG-05
REMEDI METRONIC VASCULAR GALWAY 730K O BRIEN 01-APR-05 25-OCT-18
RECHARGE TO RCPI FOR SALARIES T O BRIEN 01-DEC-04 27-MAY-10
SFI REMEDI SUPP EQT TIM O'BRIEN F BARRY 16-NOV-04 15-NOV-05
IRCSET SC 2004 BO475 NEW ANDREW HILLMANN 01-OCT-04 31-JAN-08
HRB ENOS EXPRESSING EPCS PLUS RHR365 T O'BRIEN 01-JUL-04 25-APR-08
SFI REMEDI WP1 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI WP12 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI WP11 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI WP4 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI WP13TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI COLLABORATORS OVERHEADS TIM OBRIEN 01-JAN-04 31-DEC-08
SFI REMEDI WP5 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI OVERHEADS NUIG TIM OBRIEN 01-JAN-04 30-JUN-09
SFI REMEDI WP3 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI WP2 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI WP7 TIM O'BRIEN 01-JAN-04 30-JUN-09
SFI REMEDI GENERIC TIM O'BRIEN 01-JAN-04 30-JUN-09
HRB RP2003 115 TIM O BRIEN 01-OCT-03 30-SEP-10
IRCSET POST DOC PD 2002 173 SIOBHAN CONROY OBRIEN 01-JUL-03 02-FEB-06
BEQUEST CANCER GENE THERAPY T O BRIEN 13-JUN-03 13-JUN-20
HRB 2002 72 PROF T O BRIEN 01-DEC-02 30-JAN-06
HRB NS34 2002 INOS GENE THERAPY T OBRIEN 01-OCT-02 26-NOV-07
IRCSET EMBARK BRIAN KEALY T OBRIEN 01-OCT-02 11-FEB-09
IRCSET CILLIAN MCCABE T OBRIEN 01-OCT-02 11-FEB-09
DEPT OF MED EDUCATION FUND T O BRIEN 01-APR-02 31-DEC-20
LH PROTEIN STEVENS GENERAL A C 01-FEB-02 31-DEC-08
DIABETES RESEARCH PROF T O BRIEN 18-DEC-01 31-DEC-06
950 HRB O BRIEN VASC TONE 01-OCT-01 28-SEP-05
972 JDFIR GENE TRANSFER O BRIEN 01-JUL-01 28-FEB-07
PGMDB CO ORD OFFICE 01-JAN-94 01-DEC-11

Peer Reviewed Journals

  Year Publication
(2016) 'Do patient-reported measures of symptoms and health status predict mortality in hemodialysis? An assessment of POS-S Renal and EQ-5D'
Sexton, DJ,Lowney, AC,O'Seaghdha, CM,Murphy, M,O'Brien, T,Casserly, LF,Mcquillan, R,Plant, WD,Eustace, JA,Kinsella, SM,Conlon, PJ (2016) 'Do patient-reported measures of symptoms and health status predict mortality in hemodialysis? An assessment of POS-S Renal and EQ-5D'. Hemodialysis International, 20 :618-630 [DOI] [Details]
(2016) 'Ulk4 Regulates Neural Stem Cell Pool'
Liu, M,Guan, ZL,Shen, Q,Flinter, F,Dominguez, L,Ahn, JW,Collier, DA,O'Brien, T,Shen, SB (2016) 'Ulk4 Regulates Neural Stem Cell Pool'. Stem Cells, 34 :2318-2331 [DOI] [Details]
(2016) 'Scaffold and Scaffold-free Self-assembled Systems in Regenerative Medicine'
Thomas, D., Gaspar, D., Sorushanova, A., Milcovich, G Spanoudes, K Mullen, AM; O'Brien, T; Pandit, A., Zeugolis, D. (2016) 'Scaffold and Scaffold-free Self-assembled Systems in Regenerative Medicine'. Biotechnology And Bioengineering, 113 (6):1155-1163 [Details]
(2015) 'ROCK activity and the Gbetagamma complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'
Ryan, C. M.,Brown, J. A.,Bourke, E.,Prendergast, A. M.,Kavanagh, C.,Liu, Z.,Owens, P.,Shaw, G.,Kolch, W.,O'Brien, T.,Barry, F. P. (2015) 'ROCK activity and the Gbetagamma complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'. Stem Cell Res Ther, 6 [Details]
(2016) 'Characterization of Patients with Diabetic Foot Disease Presenting to an Irish Podiatry Centre: Profiling Suitability for Entry to a Clinical Trial of Advanced Wound Therapeutics'
Mahon AM. MacGilchrist C. McIntosh C & O’Brien T. (2016) 'Characterization of Patients with Diabetic Foot Disease Presenting to an Irish Podiatry Centre: Profiling Suitability for Entry to a Clinical Trial of Advanced Wound Therapeutics'. Irish Journal Of Medical Science, [DOI] [Details]
(2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'
Ganly, S.,Hynes, S. O.,Sharif, F.,Aied, A.,Barron, V.,McCullagh, K.,McMahon, J.,McHugh, P.,Crowley, J.,Wang, W.,O'Brien, T.,Greiser, U. (2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'. J Control Release, 167 (22):109-19 [Details]
(2013) 'Mesenchymal stem cell survival in the infarcted heart is enhanced by lentivirus vector-mediated heat shock protein 27 expression'
McGinley, L. M.,McMahon, J.,Stocca, A.,Duffy, A.,Flynn, A.,O'Toole, D.,O'Brien, T. (2013) 'Mesenchymal stem cell survival in the infarcted heart is enhanced by lentivirus vector-mediated heat shock protein 27 expression'. Hum Gene Ther, 24 (1010):840-51 [Details]
(2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'
McGinley, L.,McMahon, J.,Strappe, P.,Barry, F.,Murphy, M.,O'Toole, D.,O'Brien, T. (2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'. Stem Cell Res Ther, 2 (22) [Details]
(2010) 'Generation of antioxidant adenovirus gene transfer vectors encoding CuZnSOD, MnSOD, and catalase'
Duffy, A. M.,O'Brien, T.,McMahon, J. M. (2010) 'Generation of antioxidant adenovirus gene transfer vectors encoding CuZnSOD, MnSOD, and catalase'. Methods Mol Biol, 594 :381-93 [Details]
(2010) 'Bolus delivery of mesenchymal stem cells to injured vasculature in the rabbit carotid artery produces a dysfunctional endothelium'
O'Shea, C. A.,Hynes, S. O.,Shaw, G.,Coen, B. A.,Hynes, A. C.,McMahon, J.,Murphy, M.,Barry, F.,O'Brien, T. (2010) 'Bolus delivery of mesenchymal stem cells to injured vasculature in the rabbit carotid artery produces a dysfunctional endothelium'. Tissue Eng Part A, 16 (55):1657-65 [Details]
(2009) 'Comparison of viral and nonviral vectors for gene transfer to human endothelial progenitor cells'
Kealy, B.,Liew, A.,McMahon, J. M.,Ritter, T.,O'Doherty, A.,Hoare, M.,Greiser, U.,Vaughan, E. E.,Maenz, M.,O'Shea, C.,Barry, F.,O'Brien, T. (2009) 'Comparison of viral and nonviral vectors for gene transfer to human endothelial progenitor cells'. Tissue Eng Part C Methods, 15 (22):223-31 [Details]
(2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'
Sen, S.,Conroy, S.,Hynes, S. O.,McMahon, J.,O'Doherty, A.,Bartlett, J. S.,Akhtar, Y.,Adegbola, T.,Connolly, C. E.,Sultan, S.,Barry, F.,Katusic, Z. S.,O'Brien, T. (2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'. J Gene Med, 10 (22):143-51 [Details]
(2008) 'Gene-eluting stents: adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis'
Sharif, F.,Hynes, S. O.,Cooney, R.,Howard, L.,McMahon, J.,Daly, K.,Crowley, J.,Barry, F.,O'Brien, T. (2008) 'Gene-eluting stents: adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis'. Mol Ther, 16 (1010):1674-80 [Details]
(2006) 'Gene-eluting stents: comparison of adenoviral and adeno- associated viral gene delivery to the blood vessel wall in vivo'
Sharif, F.,Hynes, S. O.,McMahon, J.,Cooney, R.,Conroy, S.,Dockery, P.,Duffy, G.,Daly, K.,Crowley, J.,Bartlett, J. S.,O'Brien, T. (2006) 'Gene-eluting stents: comparison of adenoviral and adeno- associated viral gene delivery to the blood vessel wall in vivo'. Hum Gene Ther, 17 (77):741-50 [Details]
(2006) 'Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors'
McMahon, J. M.,Conroy, S.,Lyons, M.,Greiser, U.,O'Shea, C.,Strappe, P.,Howard, L.,Murphy, M.,Barry, F.,O'Brien, T. (2006) 'Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors'. Stem Cells Dev, 15 (11):87-96 [Details]
(2017) 'Biodistribution and retention of locally administered human mesenchymal stromal cells: Quantitative polymerase chain reaction based detection of human DNA in murine organs'
Creane, M,Howard, L,O'Brien, T,Coleman, CM (2017) 'Biodistribution and retention of locally administered human mesenchymal stromal cells: Quantitative polymerase chain reaction based detection of human DNA in murine organs'. Cytotherapy, 19 :384-394 [DOI] [Details]
(2016) 'Rapamycin Regulates Autophagy and Cell Adhesion in Induced Pluripotent Stem Cells'
4. Kunath, T., Sotthibundhul, A., McDonagh, K., Von Kriegsheim, A., Garcia-Munoz, A., Klawiter, A., Thompson, K., Dev Chauhan, K., Krawczyk, J., McInerney, V. and Dockery, P., Devine, MJ, Barry, F, O'Brien, T & Shen, S (2016) 'Rapamycin Regulates Autophagy and Cell Adhesion in Induced Pluripotent Stem Cells'. Stem Cell Research & Therapy, 7 (166) [DOI] [Details]
(2017) 'Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms'
Madill, M,McDonagh, K,Ma, J,Vajda, A,McLoughlin, P,O'Brien, T,Hardiman, O,Shen, SB (2017) 'Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms'. Molecular Brain, 10 [DOI] [Details]
(2017) 'Characterization of patients with diabetic foot disease presenting to an Irish Podiatry Centre: profiling suitability for entry to a clinical trial of advanced wound therapeutics'
Mahon, AM,MacGilchrist, C,McIntosh, C,O'Brien, T (2017) 'Characterization of patients with diabetic foot disease presenting to an Irish Podiatry Centre: profiling suitability for entry to a clinical trial of advanced wound therapeutics'. Irish Journal Of Medical Science, 186 :659-669 [DOI] [Details]
(2015) 'ROCK activity and the G beta gamma complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'
Ryan, CM,Brown, JAL,Bourke, E,Prendergast, AM,Kavanagh, C,Liu, ZL,Owens, P,Shaw, G,Kolch, W,O'Brien, T,Barry, FP (2015) 'ROCK activity and the G beta gamma complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'. Stem Cell Research & Therapy, 6 [DOI] [Details]
(2017) 'Manufacturing Differences Affect Human Bone Marrow Stromal Cell Characteristics and Function: Comparison of Production Methods and Products from Multiple Centers'
Liu, ST,de Castro, LF,Jin, P,Civini, S,Ren, JQ,Reems, JA,Cancelas, J,Nayak, R,Shaw, G,O'Brien, T,McKenna, DH,Armant, M,Silberstein, L,Gee, AP,Hei, DJ,Hematti, P,Kuznetsov, SA,Robey, PG,Stroncek, DF (2017) 'Manufacturing Differences Affect Human Bone Marrow Stromal Cell Characteristics and Function: Comparison of Production Methods and Products from Multiple Centers'. Scientific Reports, 7 [DOI] [Details]
(2017) 'Multiple roles of Ulk4 in neurogenesis and brain function'
Liu M, Xu P, O'Brien T, Shen S. (2017) 'Multiple roles of Ulk4 in neurogenesis and brain function'. Neurogenetics, 23 (4(1):e1313646) [DOI] [Details]
(2017) 'Biodistribution and retention of locally administered human mesenchymal stromal cells: Quantitative polymerase chain reaction based detection of human DNA in murine organs'
Creane, M;Howard, L;O'Brien, T;Coleman, CM (2017) 'Biodistribution and retention of locally administered human mesenchymal stromal cells: Quantitative polymerase chain reaction based detection of human DNA in murine organs'. Cytotherapy, 19 :384-394 [DOI] [Details]
(2017) 'Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms'
Madill, M;McDonagh, K;Ma, J;Vajda, A;McLoughlin, P;O'Brien, T;Hardiman, O;Shen, SB (2017) 'Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms'. Molecular Brain, 10 [DOI] [Details]
(2016) 'Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - A step closer to physiologically relevant in vitro organogenesis'
Cigognini, D;Gaspar, D;Kumar, P;Satyam, A;Alagesan, S;Sanz-Nogues, C;Griffin, M;O'Brien, T;Pandit, A;Zeugolis, DI (2016) 'Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - A step closer to physiologically relevant in vitro organogenesis'. Scientific Reports, 6 [DOI] [Details]
(2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'
Leszczynska, A,O'Doherty, A,Farrell, E,Pindjakova, J,O'Brien, FJ,O'Brien, T,Barry, F,Murphy, M (2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'. Stem Cells, 34 :913-923 [DOI] [Details]
(2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'
Leszczynska A;O'Doherty A;Farrell E;Pindjakova J;O'Brien FJ;O'Brien T;Barry F;Murphy M; (2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'. Stem Cells (Dayton, Ohio), 34 (4) [DOI] [ARAN Link] [Details]
(2016) 'Ulk4 Regulates Neural Stem Cell Pool'
Liu, M;Guan, ZL;Shen, Q;Flinter, F;Dominguez, L;Ahn, JW;Collier, DA;O'Brien, T;Shen, SB (2016) 'Ulk4 Regulates Neural Stem Cell Pool'. Stem Cells (Dayton, Ohio), 34 :2318-2331 [DOI] [Details]
(2016) 'Co-transfection of decorin and interleukin-10 modulates pro-fibrotic extracellular matrix gene expression in human tenocyte culture'
Abbah, SA;Thomas, D;Browne, S;O'Brien, T;Pandit, A;Zeugolis, DI (2016) 'Co-transfection of decorin and interleukin-10 modulates pro-fibrotic extracellular matrix gene expression in human tenocyte culture'. Scientific Reports, 6 [DOI] [Details]
(2016) 'Endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B') in human arterial smooth muscle cells'
McCullagh, KJA,Cooney, R,O'Brien, T (2016) 'Endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B') in human arterial smooth muscle cells'. Nitric Oxide-Biology And Chemistry, 52 :41-48 [DOI] [Details]
(2016) 'Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells'
Sotthibundhu, A,McDonagh, K,von Kriegsheim, A,Garcia-Munoz, A,Klawiter, A,Thompson, K,Chauhan, KD,Krawczyk, J,McInerney, V,Dockery, P,Devine, MJ,Kunath, T,Barry, F,O'Brien, T,Shen, S (2016) 'Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells'. Stem Cell Research & Therapy, 7 [DOI] [Details]
(2016) 'Co-transfection of decorin and interleukin-10 modulates pro-fibrotic extracellular matrix gene expression in human tenocyte culture'
Abbah, SA,Thomas, D,Browne, S,O'Brien, T,Pandit, A,Zeugolis, DI (2016) 'Co-transfection of decorin and interleukin-10 modulates pro-fibrotic extracellular matrix gene expression in human tenocyte culture'. Scientific Reports, 6 [DOI] [Details]
(2016) 'Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - A step closer to physiologically relevant in vitro organogenesis'
Cigognini, D,Gaspar, D,Kumar, P,Satyam, A,Alagesan, S,Sanz-Nogues, C,Griffin, M,O'Brien, T,Pandit, A,Zeugolis, DI (2016) 'Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - A step closer to physiologically relevant in vitro organogenesis'. Scientific Reports, 6 [DOI] [Details]
(2016) 'Ulk4 Is Essential for Ciliogenesis and CSF Flow'
Liu, M,Guan, ZL,Shen, Q,Lalor, P,Fitzgerald, U,O'Brien, T,Dockery, P,Shen, SB (2016) 'Ulk4 Is Essential for Ciliogenesis and CSF Flow'. Journal Of Neuroscience, 36 :7589-7600 [DOI] [Details]
(2016) 'Measurement of the Postgraduate Educational Environment of Junior Doctors Training in Medicine at an Irish University Teaching Hospital'
Flaherty, GT,Connolly, R,O'Brien, T (2016) 'Measurement of the Postgraduate Educational Environment of Junior Doctors Training in Medicine at an Irish University Teaching Hospital'. Irish Journal Of Medical Science, 185 :565-571 [DOI] [Details]
(2016) 'Variability in Endogenous Perfusion Recovery of Immunocompromised Mouse Models of Limb Ischemia'
THOMAS D,THIRUMARAN A, MALLARD B, CHEN XZ, BROWNE S, WHEATLEY, AM, O'BRIEN T, PANDIT A (2016) 'Variability in Endogenous Perfusion Recovery of Immunocompromised Mouse Models of Limb Ischemia'. Tissue Engineering Part C-Methods, 22 :370-381 [DOI] [Details]
(2015) 'Inefficiency in macromolecular transport of SCS-based microcapsules affects viability of primary human mesenchymal stem cells but not of immortalized cells'
Sanz-Nogués C;Horan J;Thompson K;Howard L;Ryan G;Kassem M;O'Brien T; (2015) 'Inefficiency in macromolecular transport of SCS-based microcapsules affects viability of primary human mesenchymal stem cells but not of immortalized cells'. Journal Of Biomedical Materials Research Part A, 103 (11) [DOI] [Details]
(2015) 'Scaffold and Scaffold-free Self-assembled Systems in Regenerative Medicine'
Thomas, D., Gaspar, D., Sorushanova, A., Milcovich, G Spanoudes, K Mullen, AM; O'Brien, T; Pandit, A., Zeugolis, D. (2015) 'Scaffold and Scaffold-free Self-assembled Systems in Regenerative Medicine'. Biotechnology And Bioengineering, [DOI] [Details]
(2015) 'Bone Marrow-Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy'
Gleeson, BM,Martin, K,Ali, MT,Kumar, AHS,Pillai, MGK,Kumar, SPG,O'Sullivan, JF,Whelan, D,Stocca, A,Khider, W,Barry, FP,O'Brien, T,Caplice, NM (2015) 'Bone Marrow-Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy'. Stem Cells, 33 :2726-2737 [DOI] [Details]
(2015) 'Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat'
Devaney, J,Horie, S,Masterson, C,Elliman, S,Barry, F,O'Brien, T,Curley, GF,O'Toole, D,Laffey, JG (2015) 'Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat'. Thorax, 70 :625-635 [DOI] [Details]
(2015) 'ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'
Ryan CM, Brown JA, Bourke E, Prendergast ÁM, Kavanagh C, Liu Z, Owens P, Shaw G, Kolch W, O'Brien T, Barry FP. (2015) 'ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'. Stem Cell Research & Therapy, 6 (1) [Details]
(2015) 'Endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B’) in human arterial smooth muscle cells'
McCullagh, K.J.A., Cooney, R.J. and O’Brien, T (2015) 'Endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B’) in human arterial smooth muscle cells'. Nitric Oxide, [ARAN Link] [Details]
(2015) 'An injectable elastin-based gene delivery platform for dose-dependent modulation of angiogenesis and inflammation for critical limb ischemia'
Dash, BC,Thomas, D,Monaghan, M,Carroll, O,Chen, XZ,Woodhouse, K,O'Brien, T,Pandit, A (2015) 'An injectable elastin-based gene delivery platform for dose-dependent modulation of angiogenesis and inflammation for critical limb ischemia'. Biomaterials, 65 :126-139 [DOI] [ARAN Link] [Details]
(2015) 'Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat'
Hayes, M,Masterson, C,Devaney, J,Barry, F,Elliman, S,O'Brien, T,O'Toole, D,Curley, GF,Laffey, JG (2015) 'Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat'. Anesthesiology, 122 :363-373 [DOI] [Details]
(2015) 'ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'
Ryan CM, Brown JA, Bourke E, Prendergast ÁM, Kavanagh C, Liu Z, Owens P, Shaw G, Kolch W, O'Brien T, Barry FP (2015) 'ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells'. Stem Cell Res Ther, 6(1) (136) [DOI] [Details]
(2015) 'Aerosol-Mediated Delivery of AAV2/6-I kappa B alpha Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats'
MacLoughlin, RJ,Higgins, BD,Devaney, J,O'Toole, D,Laffey, JG,O'Brien, T (2015) 'Aerosol-Mediated Delivery of AAV2/6-I kappa B alpha Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats'. Human Gene Therapy, 26 :36-46 [DOI] [Details]
(2015) 'Effects of an eight-week supervised, structured lifestyle modification programme on anthropometric, metabolic and cardiovascular risk factors in severely obese adults'
Crowe C, Gibson I, Cunning K, Kerins C, Costello C, Windle J, O'Shea PM, Hynes M, MGuire BE, Kilkelly K, Griffin H, O'Brien T, Jones J, Finucane FM. (2015) 'Effects of an eight-week supervised, structured lifestyle modification programme on anthropometric, metabolic and cardiovascular risk factors in severely obese adults'. BMC Endocr Disord, [DOI] [Details]
(2015) 'Inefficiency in macromolecular transport of SCS-based microcapsules affects viability of primary human mesenchymal stem cells but not of immortalized cells'
Sanz-Nogués C, Horan J, Thompson K, Howard L, Ryan G, Kassem M, O'Brien T (2015) 'Inefficiency in macromolecular transport of SCS-based microcapsules affects viability of primary human mesenchymal stem cells but not of immortalized cells'. Journal Of Biomedical Materials Research Part A, [DOI] [Details]
(2015) 'Inefficiency in macromolecular transport of SCS-based microcapsules affects viability of primary human mesenchymal stem cells but not of immortalized cells'
Sanz-Nogues, C,Horan, J,Thompson, K,Howard, L,Ryan, G,Kassem, M,O'Brien, T (2015) 'Inefficiency in macromolecular transport of SCS-based microcapsules affects viability of primary human mesenchymal stem cells but not of immortalized cells'. Journal Of Biomedical Materials Research Part A, 103 :3676-3688 [DOI] [Details]
(2014) 'MSCs isolated from patients with ischemic vascular disease have normal angiogenic potential'
Sanz-Nogués C;O'Brien T; (2014) 'MSCs isolated from patients with ischemic vascular disease have normal angiogenic potential'. Molecular Therapy : The Journal Of The American Society Of Gene Therapy, 22 (11) [DOI] [Details]
(2014) 'A shape-controlled tuneable microgel platform to modulate angiogenic paracrine responses in stem cells'
Thomas D;Fontana G;Chen X;Sanz-Nogués C;Zeugolis DI;Dockery P;O'Brien T;Pandit A; (2014) 'A shape-controlled tuneable microgel platform to modulate angiogenic paracrine responses in stem cells'. Biomaterials, 35 (31) [DOI] [Details]
(2014) 'Aerosol-mediated delivery of AAV2/6-IκBα attenuates lipopolysaccharide-induced acute lung injury in rats'
MacLoughlin R, Higgins BD, Devaney J, O'Toole d, Laffey DG, O'Brien T. (2014) 'Aerosol-mediated delivery of AAV2/6-IκBα attenuates lipopolysaccharide-induced acute lung injury in rats'. Human Gene Therapy, [Details]
(2014) 'Glycaemic control is harder to achieve than blood pressure or lipid control in Irish adults with type 1 diabetes'
Cotter, TG,Dinneen, SF,Healy, DA,Bell, MJ,Cunningham, A,O'Shea, PM,Dunne, F,O'Brien, T,Finucane, FM (2014) 'Glycaemic control is harder to achieve than blood pressure or lipid control in Irish adults with type 1 diabetes'. Diabetes Research And Clinical Practice, 106 :56-59 [DOI] [Details]
(2014) 'Mesenchymal Stromal Cell Therapy for Crohn's Disease'
Liew, A,O'Brien, T,Egan, L (2014) 'Mesenchymal Stromal Cell Therapy for Crohn's Disease'. Digestive Diseases, 32 :50-60 [DOI] [Details]
(2014) 'Upregulation of autophagy by rapamycin induces spontaneous formation of uniform embryoid bodies and accelerates differentiation of human induced pluripotent stem cells'
Sotthibundhu A, McDonagh K, Klawiter A, Thompson K, Dockery P, Devine M, Kunath T, O’Brien T, Barry F, Shen S* (2014) 'Upregulation of autophagy by rapamycin induces spontaneous formation of uniform embryoid bodies and accelerates differentiation of human induced pluripotent stem cells'. Autophagy, [Details]
(2014) 'A shape-controlled tuneable microgel platform to modulate angiogenic paracrine responses in stem cells'
Thomas D, Fontana G, Chen X, Sanz-Nogués C, Zeugolis DI, Dockery P, O'Brien T, Pandit A (2014) 'A shape-controlled tuneable microgel platform to modulate angiogenic paracrine responses in stem cells'. Biomaterials, 35 (31):8757-8766 [DOI] [Details]
(2014) 'Comparison of Cellular Architecture, Axonal Growth, and Blood Vessel Formation Through Cell-Loaded Polymer Scaffolds in the Transected Rat Spinal Cord'
Madigan NN, Chen BK, Knight AM, Rooney GE, Sweeney E, Kinnavane L, Yaszemski MJ, Dockery P, O'Brien T, McMahon SS, Windebank AJ. (2014) 'Comparison of Cellular Architecture, Axonal Growth, and Blood Vessel Formation Through Cell-Loaded Polymer Scaffolds in the Transected Rat Spinal Cord'. Tissue Engineering Part A, [Details]
(2014) 'Comparison of cellular architecture, axonal growth, and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord'
Madigan NN, Chen BK, Knight AM, Rooney GE, Sweeney E, Kinnavane L, Yaszemski MJ, Dockery P, O'Brien T, McMahon SS, Windebank AJ (2014) 'Comparison of cellular architecture, axonal growth, and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord'. Tissue Engineering, 20 (21-22):2985-2997 [DOI] [Details]
(2014) 'Influence of adiposity on insulin requirements and glycaemic control in children and adolescents with type 1 diabetes'
Cotter T, Jennings P, Burke H, Dinneen SF, Bell M, Dunne F,Geoghegan R,Moylett E, O'Brien, T, Finucane, FM. (2014) 'Influence of adiposity on insulin requirements and glycaemic control in children and adolescents with type 1 diabetes'. Irish Journal Of Medical Science, 183 [Details]
(2014) 'Glycaemic control is harder to achieve than blood pressure or lipid control in Irish adults with type 1 diabetes'
Cotter TG, Dinneen SF, Healy DA, Bell MJ, Cunningham A, O'Shea PM, Dunne F, O'Brien T, Finucane FM (2014) 'Glycaemic control is harder to achieve than blood pressure or lipid control in Irish adults with type 1 diabetes'. Diabetes Res Clin Pract, 106 (3):1-9 [DOI] [Details]
(2014) 'Stem cell tourism - A web-based analysis of clinical services available to international travellers'
Connolly, R,O'Brien, T,Flaherty, G (2014) 'Stem cell tourism - A web-based analysis of clinical services available to international travellers'. Travel Medicine And Infectious Disease, 12 :695-701 [DOI] [Details]
(2014) 'The Potential of Cell-based Therapy for Diabetes and Diabetes-related Vascular Complications'
Liew, A,O'Brien, T (2014) 'The Potential of Cell-based Therapy for Diabetes and Diabetes-related Vascular Complications'. Current Diabetes Reports, 14 [DOI] [Details]
(2014) 'A shape-controlled tuneable microgel platform to modulate angiogenic paracrine responses in stem cells'
Thomas, D,Fontana, G,Chen, XZ,Sanz-Nogues, C,Zeugolis, DI,Dockery, P,O'Brien, T,Pandit, A (2014) 'A shape-controlled tuneable microgel platform to modulate angiogenic paracrine responses in stem cells'. Biomaterials, 35 (31):8757-8766 [DOI] [Details]
(2014) 'Assessment of stem cell carriers for tendon tissue engineering in pre-clinical models'
Abbah, SA,Spanoudes, K,O'Brien, T,Pandit, A,Zeugolis, DI (2014) 'Assessment of stem cell carriers for tendon tissue engineering in pre-clinical models'. Stem Cell Research & Therapy, 5 [DOI] [Details]
(2014) 'Use of a fibrin-based system for enhancing angiogenesis and modulating inflammation in the treatment of hyperglycemic wounds'
Kulkarni, M,O'Loughlin, A,Vazquez, R,Mashayekhi, K,Rooney, P,Greiser, U,O'Toole, E,O'Brien, T,Malagon, MM,Pandit, A (2014) 'Use of a fibrin-based system for enhancing angiogenesis and modulating inflammation in the treatment of hyperglycemic wounds'. Biomaterials, 35 (6):2001-2010 [DOI] [Details]
(2014) 'The Potential of Cell-based Therapy for Diabetes and Diabetes-related Vascular Complications'
Liew A, O'Brien T. (2014) 'The Potential of Cell-based Therapy for Diabetes and Diabetes-related Vascular Complications'. Current Diabetes Reports, [Details]
(2014) 'Assessment of stem cell carriers for tendon tissue engineering in pre-clinical models'
Abbah SA, Spanoudes, K. O’Brien T, Pandit, Zeugolis D (2014) 'Assessment of stem cell carriers for tendon tissue engineering in pre-clinical models'. Stem Cell Research And Therapy, [Details]
(2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'
Hogan NM, Joyce MR, Murphy JM, Barry FP, O'Brien T, Kerin MJ, Dwyer RM (2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'. Biochem Biophy Res Commun, [DOI] [Details]
(2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'
O'Loughlin, A,Kulkarni, M,Vaughan, EE,Creane, M,Liew, A,Dockery, P,Pandit, A,O'Brien, T (2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'. Stem Cell Research & Therapy, 4 [DOI] [Details]
(2013) 'The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats'
Mulcahy, P,O'Doherty, A,Paucard, A,O'Brien, T,Kirik, D,Dowd, E (2013) 'The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats'. Behavioural Brain Research, 243 :6-15 [DOI] [Details]
(2013) 'Effects of Intratracheal Mesenchymal Stromal Cell Therapy during Recovery and Resolution after Ventilator-induced Lung Injury'
Curley, GF,Ansari, B,Hayes, M,Devaney, J,Masterson, C,Ryan, A,Barry, F,O'Brien, T,O' Toole, D,Laffey, JG (2013) 'Effects of Intratracheal Mesenchymal Stromal Cell Therapy during Recovery and Resolution after Ventilator-induced Lung Injury'. Anesthesiology, 118 :924-933 [DOI] [Details]
(2013) 'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix'
Tierney, EG,McSorley, K,Hastings, CL,Cryan, SA,O'Brien, T,Murphy, MJ,Barry, FP,O'Brien, FJ,Duffy, GP (2013) 'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix'. J Control Release, 165 :173-182 [DOI] [Details]
(2013) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'
Riegler, J,Liew, A,Hynes, SO,Ortega, D,O'Brien, T,Day, RM,Richards, T,Sharif, F,Pankhurst, QA,Lythgoe, MF (2013) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'. Biomaterials, 34 :1987-1994 [DOI] [Details]
(2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'
O'Loughlin A, Kulkarni M, Vaughan EE, Creane M, Liew A, Dockery P, Pandit A, O'Brien T (2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'. Stem Cell Research & Therapy, 4 (6) [DOI] [Details]
(2013) 'Restructuring of the Diabetes Day Centre: a pilot lean project in a tertiary referral centre in the West of Ireland'
McDermott, A. M.,Kidd, P.,Gately, M.,Casey, R.,Burke, H.,O'Donnell, P.,Kirrane, F.,Dinneen, S. F.,O'Brien, T. (2013) 'Restructuring of the Diabetes Day Centre: a pilot lean project in a tertiary referral centre in the West of Ireland'. Bmj Quality & Safety, 22 (88):681-688 [Details]
(2013) 'Robust, Efficient, and Practical Electrogene Transfer Method for Human Mesenchymal Stem Cells Using Square Electric Pulses'
Liew, A,Andre, FM,Lesueur, LL,De Menorval, MA,O'Brien, T,Mir, LM (2013) 'Robust, Efficient, and Practical Electrogene Transfer Method for Human Mesenchymal Stem Cells Using Square Electric Pulses'. Human Gene Therapy Methods, 24 :289-297 [DOI] [Details]
(2013) 'Stem Cell Microencapsulation for Therapeutic Angiogenesis'
Nogues, CS,Thomas, D,Pandit, A,O'Brien, T,DeBartolo, L,Bader, A (2013) 'Stem Cell Microencapsulation for Therapeutic Angiogenesis'. Biomaterials For Stem Cell Therapy: State Of Art And Vision For The Future, :386-424 [Details]
(2013) 'Lipsosmal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'
Ganly, S., Hynes, S.O. Sharif, F., Aid, A., Barron, V., McCullagh, K.J.A., McMahon, J., McHugh, P.E., Crowley, J., Barry, F., Wang, W., O'Brien, T., Greiser, U. (2013) 'Lipsosmal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'. Journal Of Controlled Release, 167 :109-119 [Details]
(2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'
Ganly S, Hynes SO, Sharif F, Aied A, Barron V, McCullagh K, McMahon J, McHugh P, Crowley J, Wang W, O'Brien T, Greiser U (2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'. J Control Release, 167 (2):109-119 [Details]
(2013) 'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix'
Tierney EG, McSorley K, Hastings CL, Cryan SA, O'Brien T, Murphy MJ, Barry FP, O'Brien FJ, Duffy GP (2013) 'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix'. J Control Release, 165 (3):173-182 [DOI] [Details]
(2013) 'Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury'
Curley GF, Ansari B, Hayes M, Devaney J, Masterson C, Ryan A, Barry F, O'Brien T, Toole DO, Laffey JG (2013) 'Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury'. Anesthesiology, 118 (4):924-932 [DOI] [Details]
(2013) 'Topical Administration of Allogeneic Mesenchymal Stromal Cells Seeded in a Collagen Scaffold Augments Wound Healing and Increases Angiogenesis in the Diabetic Rabbit Ulcer'
O'Loughlin, A,Kulkarni, M,Creane, M,Vaughan, EE,Mooney, E,Shaw, G,Murphy, M,Dockery, P,Pandit, A,O'Brien, T (2013) 'Topical Administration of Allogeneic Mesenchymal Stromal Cells Seeded in a Collagen Scaffold Augments Wound Healing and Increases Angiogenesis in the Diabetic Rabbit Ulcer'. Diabetes, 62 :2588-2594 [DOI] [Details]
(2013) 'Impact of Mesenchymal Stem Cell secreted PAI-1 on colon cancer cell migration and proliferation'
Hogan, NM,Joyce, MR,Murphy, JM,Barry, FP,O'Brien, T,Kerin, MJ,Dwyer, RM (2013) 'Impact of Mesenchymal Stem Cell secreted PAI-1 on colon cancer cell migration and proliferation'. Biochemical And Biophysical Research Communications, 435 :574-579 [DOI] [Details]
(2013) 'Restructuring of the Diabetes Day Centre: a pilot lean project in a tertiary referral centre in the West of Ireland'
McDermott, AM,Kidd, P,Gately, M,Casey, R,Burke, H,O'Donnell, P,Kirrane, F,Dinneen, SF,O'Brien, T (2013) 'Restructuring of the Diabetes Day Centre: a pilot lean project in a tertiary referral centre in the West of Ireland'. Bmj Quality & Safety, 22 :681-688 [DOI] [Details]
(2013) 'Mesenchymal Stem Cell Survival in the Infarcted Heart Is Enhanced by Lentivirus Vector-Mediated Heat Shock Protein 27 Expression'
McGinley, LM,McMahon, J,Stocca, A,Duffy, A,Flynn, A,O'Toole, D,O'Brien, T (2013) 'Mesenchymal Stem Cell Survival in the Infarcted Heart Is Enhanced by Lentivirus Vector-Mediated Heat Shock Protein 27 Expression'. Human Gene Therapy, 24 :840-851 [DOI] [Details]
(2013) 'Inhibition of pulmonary nuclear factor kappa-B decreases the severity of acute Escherichia coli pneumonia but worsens prolonged pneumonia'
Devaney, J,Curley, GF,Hayes, M,Masterson, C,Ansari, B,O'Brien, T,O'Toole, D,Laffey, JG (2013) 'Inhibition of pulmonary nuclear factor kappa-B decreases the severity of acute Escherichia coli pneumonia but worsens prolonged pneumonia'. Critical care (London, England), 17 [DOI] [Details]
(2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'
Ganly, S,Hynes, SO,Sharif, F,Aied, A,Barron, V,McCullagh, K,McMahon, J,McHugh, P,Crowley, J,Wang, WX,O'Brien, T,Greiser, U (2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'. J Control Release, 167 :109-119 [DOI] [Details]
(2012) 'A role for MRP8 in in stent restenosis in diabetes'
Stocca, A; O'Toole, D; Hynes, N; Hynes, S; Mashayekhi, K; McGinley, L; Coleman, C.M; Sultan, S; Duffy, A; Tuney, T; O'Brien, T (2012) 'A role for MRP8 in in stent restenosis in diabetes'. Atherosclerosis, 221 (2):325-332 [Details]
(2012) 'DEVELOPMENT AND CHARACTERISATION OF A NOVEL RAT MODEL OF PARKINSON'S DISEASE INDUCED BY SEQUENTIAL INTRANIGRAL ADMINISTRATION OF AAV-alpha-SYNUCLEIN AND THE PESTICIDE, ROTENONE'
Mulcahy, P,O'Doherty, A,Paucard, A,O'Brien, T,Kirik, D,Dowd, E (2012) 'DEVELOPMENT AND CHARACTERISATION OF A NOVEL RAT MODEL OF PARKINSON'S DISEASE INDUCED BY SEQUENTIAL INTRANIGRAL ADMINISTRATION OF AAV-alpha-SYNUCLEIN AND THE PESTICIDE, ROTENONE'. Neuroscience, 203 :170-179 [DOI] [Details]
(2012) 'Interference: an alteRNAtive therapy following acute myocardial infarction'
Monaghan, M,Greiser, U,Wall, JG,O'Brien, T,Pandit, A (2012) 'Interference: an alteRNAtive therapy following acute myocardial infarction'. Trends In Pharmacological Sciences, 33 :635-645 [DOI] [Details]
(2012) 'A comparison of the efficacy of transplantation of bone marrow-derived mesenchymal stem cells and unrestricted somatic stem cells on outcome after acute myocardial infarction'
Flynn, A,Chen, XZ,O'Connell, E,O'Brien, T (2012) 'A comparison of the efficacy of transplantation of bone marrow-derived mesenchymal stem cells and unrestricted somatic stem cells on outcome after acute myocardial infarction'. Stem Cell Research & Therapy, 3 [DOI] [Details]
(2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'
Donnelly EM, Madigan NN, Rooney GE, Knight A, Chen B, Ball B, Kinnavane L, Garcia Y, Dockery P, Fraher J, Strappe PM, Windebank AJ, O'Brien T, McMahon SS (2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'. Cytotherapy, 14 (10):1235-1244 [DOI] [Details]
(2012) 'Pretreatment of endothelial progenitor cells with osteopontin enhances cell therapy for peripheral vascular disease'
Vaughan EE, Liew A, Mashayekhi K, Dockery P, McDermott J, Kealy B, Flynn A, Duffy A, Coleman C, O'Regan A, Barry FP, O'Brien T (2012) 'Pretreatment of endothelial progenitor cells with osteopontin enhances cell therapy for peripheral vascular disease'. Cell, 21 (6):1095-1107 [DOI] [Details]
(2012) 'Mesenchymal Stem Cells enhance recovery and repair following Ventilation Induced Lung Injury in the Rat'
Curley G, Hayes M, Ansari B, Shaw G, Ryan A, Barry F, O’Brien T, O’Toole D, Laffey JG (2012) 'Mesenchymal Stem Cells enhance recovery and repair following Ventilation Induced Lung Injury in the Rat'. Thorax, [Details]
(2012) 'A comparison of the efficacy of transplantation of bone marrow derived mesenchymal stem cells and unrestricted somatic stem cells on outcome after acute myocardial infarction'
Flynn AW, Chen X, O'Connell E, O'Brien T (2012) 'A comparison of the efficacy of transplantation of bone marrow derived mesenchymal stem cells and unrestricted somatic stem cells on outcome after acute myocardial infarction'. Stem Cell Research & Therapy, 3 (5) [DOI] [Details]
(2012) 'Adenoviral Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses after Cell Transplantation'
Treacy, O,Ryan, AE,Heinzl, T,O'Flynn, L,Cregg, M,Wilk, M,Odoardi, F,Lohan, P,O'Brien, T,Nosov, M,Ritter, T (2012) 'Adenoviral Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses after Cell Transplantation'. Plos One, 7 [DOI] [ARAN Link] [Details]
(2012) 'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix'
Tierney EG, McSorley K, Hastings CL, Cryan SA, O'Brien T, Murphy MJ, Barry FP, O'Brien FJ, Duffy GP (2012) 'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix'. Journal Of Controlled Release, [Details]
(2012) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'
Riegler J, Liew A, Hynes SO, Ortega D, O'Brien T, Day RM, Richards T, Sharif F, Pankhurst QA, Lythgoe MF. (2012) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'. Biomaterials, [Details]
(2012) 'Development and characterisation of a novel rat model of Parkinson’s disease induced by sequential intra-nigral administration of AAV-a-synuclein and the pesticide, rotenone'
Mulcahy P, O’Doherty A, Paucard A, O’Brien T, Kirik D & Dowd E (2012) 'Development and characterisation of a novel rat model of Parkinson’s disease induced by sequential intra-nigral administration of AAV-a-synuclein and the pesticide, rotenone'. Neuroscience, [Details]
(2012) 'Immunogenicity of allogeneic mesenchymal stem cells'
Schu S; Nosov, M; O'Flynn, L; Shaw, G; Treacy, O; Barry, F; Murphy, M; O'Brien, T; Ritter, T. (2012) 'Immunogenicity of allogeneic mesenchymal stem cells'. Journal Of Cellular And Molecular Medicine, [Details]
(2012) 'Adenoviral transduction of mesenchymal stem cells: in vitro responses and in vivo immune responses after cell transplantation'
Treacy, O; Ryan, AE; Heinzl, T; O'Flynn, L; Cregg, M; Wilk, M; Odoardi, F; Lohan, P; O'Brien, T; Nosov, M; Ritter, T. (2012) 'Adenoviral transduction of mesenchymal stem cells: in vitro responses and in vivo immune responses after cell transplantation'. Plos One, [Details]
(2012) 'Immunogenicity of allogeneic mesenchymal stem cells'
Schu, S,Nosov, M,O'Flynn, L,Shaw, G,Treacy, O,Barry, F,Murphy, M,O'Brien, T,Ritter, T (2012) 'Immunogenicity of allogeneic mesenchymal stem cells'. Journal Of Cellular And Molecular Medicine, 16 :2094-2103 [DOI] [ARAN Link] [Details]
(2012) 'A Role for MRP8 in in stent restenosis in diabetes'
Stocca, A,O'Toole, D,Hynes, N,Hynes, SO,Mashayekhi, K,McGinley, L,O'Connell, E,Coleman, C,Sultan, S,Duffy, A,Tunev, S,O'Brien, T (2012) 'A Role for MRP8 in in stent restenosis in diabetes'. Atherosclerosis, 221 :325-332 [DOI] [Details]
(2012) 'Pretreatment of Endothelial Progenitor Cells With Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'
Vaughan, EE,Liew, A,Mashayekhi, K,Dockery, P,McDermott, J,Kealy, B,Flynn, A,Duffy, A,Coleman, C,O'Regan, A,Barry, FP,O'Brien, T (2012) 'Pretreatment of Endothelial Progenitor Cells With Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'. Cell Transplantation, 21 :1095-1107 [DOI] [Details]
(2012) 'Gene-Eluting Stents: liposome-based eNOS enhances re-endothelialisation but does not prevent restenosis in a hypercholesterolemic model'
Sharif F, Hynes S, McCullagh KJA, Ganley S, Geiser U, McHugh P, Crowley J, Barry F, O'Brien T. (2012) 'Gene-Eluting Stents: liposome-based eNOS enhances re-endothelialisation but does not prevent restenosis in a hypercholesterolemic model'. Gene Therapy. Impact Factor 4.8, [Details]
(2012) 'Autologous Circulating Angiogenic Cells Treated with Osteopontin and Delivered Via a Collagen Scaffold Enhances Wound Healing in the Alloxan-Induced Diabetic Rabbit Ear Ulcer Model'
O'Loughlin, A,Kulkarni, M,Vaughan, EE,Creane, M,Liew, A,Dockery, P,Pandit, A,O'Brien, T (2012) 'Autologous Circulating Angiogenic Cells Treated with Osteopontin and Delivered Via a Collagen Scaffold Enhances Wound Healing in the Alloxan-Induced Diabetic Rabbit Ear Ulcer Model'. Diabetes, :290-290 [Details]
(2012) 'Optimal Electrogene Transfer Method for Human Mesenchymal Stem Cells'
Liew, A,Andre, F,De Menorval, MA,O'Brien, T,Mir, L (2012) 'Optimal Electrogene Transfer Method for Human Mesenchymal Stem Cells'. Human Gene Therapy Methods, :242-243 [Details]
(2012) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhances wound healing in the alloxan-induced diabetic rabbit ear ulcer model'
O'Loughlin, A,Mangesh, M,Vaughan, EE,Creane, M,Liew, A,Dockery, P,Pandit, A,O'Brien, T (2012) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhances wound healing in the alloxan-induced diabetic rabbit ear ulcer model'. Stem Cell Research & Therapy, :248-248 [Details]
(2012) 'Therapeutic potential for mesenchymal stem cell transplantation in critical limb ischemia'
Liew A, O’Brien T (2012) 'Therapeutic potential for mesenchymal stem cell transplantation in critical limb ischemia'. Stem Cell Res Ther, [Details]
(2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'
Donnelly, EM,Madigan, NN,Rooney, GE,Knight, A,Chen, BK,Ball, B,Kinnavane, L,Garcia, Y,Dockery, P,Fraher, J,Strappe, PM,Windebank, AJ,O'Brien, T,McMahon, SS (2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'. Cytotherapy, 14 :1235-1244 [DOI] [Details]
(2012) 'Interference: an alteRNAtive therapy following acute myocardial infarction'
Monaghan M, Greiser U, Wall JG, O'Brien T, Pandit A (2012) 'Interference: an alteRNAtive therapy following acute myocardial infarction'. Trends In Pharmacological Sciences, [Details]
(2012) 'Typical investigational medicinal products follow relatively uniform regulations in 10 European Clinical Research Infrastructures Network (ECRIN) countries'
Gluud, C,Kubiak, C,Whitfield, K,Byrne, J,Huemer, KH,Thirstrup, S,Libersa, C,Barraud, B,Grahlert, X,Dreier, G,Geismann, S,Kuchinke, W,Temesvari, Z,Blasko, G,Kardos, G,O'Brien, T,Cooney, M,Gaynor, S,Schieppati, A,de Andres, F,Sanz, N,Kreis, G,Asker-Hagelberg, C,Johansson, H,Bourne, S,Asghar, A,Husson, JM,Demotes-Mainard, J (2012) 'Typical investigational medicinal products follow relatively uniform regulations in 10 European Clinical Research Infrastructures Network (ECRIN) countries'. Trials, 13 [DOI] [Details]
(2012) 'Gene-eluting stents: non-viral, lipsome-based gene delivery of eNOS to the blood vessel wall in-vivo results in enhanced endothelialisation but does not reduce restenosis in a hypercholesterolemic model'
Sharif, F., Hynes, S.O., McCullagh, K.J.A., Ganly, S., Greiser, U., McHugh, P.E., Crowley, J., Barry, F., O'Brien, T. (2012) 'Gene-eluting stents: non-viral, lipsome-based gene delivery of eNOS to the blood vessel wall in-vivo results in enhanced endothelialisation but does not reduce restenosis in a hypercholesterolemic model'. Gene Therapy, 19 :321-328 [DOI] [Details]
(2012) 'Pre-treatment of Endothelial Progenitor Cells with Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'
Vaughan, E; Liew, A; Mashayekhi, K; Dockery, P; McDermott, J; Kealy, B; Flynn, A; Duffy, A; Coleman, C.M.; O'Regan A; Barry, F; O'Brien, T. (2012) 'Pre-treatment of Endothelial Progenitor Cells with Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'. Cell Transplantation, 21 (6):1095-1107 [Details]
(2012) 'Gene-eluting stents: non-viral, liposome-based gene delivery of eNOS to the blood vessel wall in vivo results in enhanced endothelialization but does not reduce restenosis in a hypercholesterolemic model'
Sharif, F,Hynes, SO,McCullagh, KJA,Ganley, S,Greiser, U,McHugh, P,Crowley, J,Barry, F,O'Brien, T (2012) 'Gene-eluting stents: non-viral, liposome-based gene delivery of eNOS to the blood vessel wall in vivo results in enhanced endothelialization but does not reduce restenosis in a hypercholesterolemic model'. Gene Therapy, 19 :321-328 [DOI] [Details]
(2011) 'beta Cell Protection by Inhibition of iNOS Through Lentiviral Vector-Based Strategies'
Hynes, SO,McCabe, C,O'Brien, T,McCarthy, HO,Coulter, JA (2011) 'beta Cell Protection by Inhibition of iNOS Through Lentiviral Vector-Based Strategies'. Methods Mol Biol, 704 :153-168 [DOI] [Details]
(2011) 'Mesenchymal Stem Cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer'
Dwyer RM;Ryan J;Havelin RJ;Morris JC;Miller BW;Liu Z;Flavin R;O'Flatharta C;Foley MJ;Barrett HH;Murphy JM;Barry FP;O'Brien T;Kerin MJ; (2011) 'Mesenchymal Stem Cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer'. Stem Cells (Dayton, Ohio), 29 (7) [DOI] [Details]
(2011) 'Stem cell therapy for cardiac disease'
Flynn A, O'Brien T. (2011) 'Stem cell therapy for cardiac disease'. Expert Opin Biol Ther Impact Factor 3.2, 11 (2):177-187 [Details]
(2011) 'Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury'
Hassett P, Curley GF, Contreras M, Masterson C, Higgins BD, O'Brien T, Devaney J, O'Toole D, Laffey JG (2011) 'Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury'. Intensive care medicine, 37 (10):1680-1687 [DOI] [Details]
(2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'
McGinley, L,McMahon, J,Strappe, P,Barry, F,Murphy, M,O'Toole, D,O'Brien, T (2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'. Stem Cell Research & Therapy, 2 [DOI] [Details]
(2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'
McGinley L, McMahon J, Strappe P, Barry F, Murphy M, O'Toole D, O'Brien T (2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'. Stem Cell Research & Therapy, 2 (2) [DOI] [Details]
(2011) 'Developing Cell-Specific Antibodies to Endothelial Progenitor Cells Using Avian Immune Phage Display Technology'
Bowes, T,Hanley, SA,Liew, A,Eglon, M,Mashayekhi, K,O'Kennedy, R,Barry, F,Taylor, WR,O'Brien, T,Griffin, MD,Finlay, WJJ,Greiser, U (2011) 'Developing Cell-Specific Antibodies to Endothelial Progenitor Cells Using Avian Immune Phage Display Technology'. Journal of biomolecular screening, 16 :744-754 [DOI] [Details]
(2011) 'Functionalized Scaffold-mediated Interleukin-10 Gene Delivery Significantly Improves Survival Rates of Stem Cells In Vivo'
Holladay, C,Power, K,Sefton, M,O'Brien, T,Gallagher, WM,Pandit, A (2011) 'Functionalized Scaffold-mediated Interleukin-10 Gene Delivery Significantly Improves Survival Rates of Stem Cells In Vivo'. Molecular Therapy, 19 :969-978 [DOI] [Details]
(2011) 'Differential miRNA Expression in Omental Adipose Tissue and in the Circulation of Obese Patients Identifies Novel Metabolic Biomarkers'
Heneghan, HM,Miller, N,McAnena, OJ,O'Brien, T,Kerin, MJ (2011) 'Differential miRNA Expression in Omental Adipose Tissue and in the Circulation of Obese Patients Identifies Novel Metabolic Biomarkers'. Journal Of Clinical Endocrinology & Metabolism, 96 :846-850 [DOI] [Details]
(2011) 'A Temporal Gene Delivery System Based on Fibrin Microspheres'
Kulltarni, MM,Greiser, U,O'Brien, T,Pandit, A (2011) 'A Temporal Gene Delivery System Based on Fibrin Microspheres'. Molecular Pharmaceutics, 8 :439-446 [DOI] [Details]
(2011) 'Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter (NIS) Supports Radionuclide Imaging and Treatment of Breast Cancer'
Dwyer RM, Ryan J, Havelin RJ, Morris JC, Miller BW, Liu Z, Flavin R, O'Flatharta C, Foley MJ, Barrett HH, Murphy JM, Barry FP, O'Brien T, Kerin MJ. (2011) 'Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter (NIS) Supports Radionuclide Imaging and Treatment of Breast Cancer'. Stem Cells, 29 :1149-57 [Details]
(2011) 'Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter Supports Radionuclide Imaging and Treatment of Breast Cancer'
Dwyer, RM,Ryan, J,Havelin, RJ,Morris, JC,Miller, BW,Liu, ZL,Flavin, R,O'Flatharta, C,Foley, MJ,Barrett, HH,Murphy, JM,Barry, FP,O'Brien, T,Kerin, MJ (2011) 'Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter Supports Radionuclide Imaging and Treatment of Breast Cancer'. Stem Cells, 29 (7):1149-1157 [DOI] [Details]
(2010) 'Basic Concepts to Novel Therapies: A Review of the Diabetic Foot'
O'Loughlin, A,McIntosh, C,Dinneen, SF,O'Brien, T (2010) 'Basic Concepts to Novel Therapies: A Review of the Diabetic Foot'. International Journal Of Lower Extremity Wounds, 9 :90-102 [DOI] [Details]
(2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'
Dwyer RM, Khan S, Barry FP, O'Brien T, Kerin MJ (2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'. Stem Cell Research & Therapy, 1 (3) [DOI] [Details]
(2010) 'Bolus delivery of mesenchymal stem cells to injured vasculature in the rabbit carotid artery produces a dysfunctional endothelium'
O'Shea CA, Hynes SO, Shaw G, Coen BA, Hynes AC, McMahon J, Murphy M, Barry F, O'Brien T (2010) 'Bolus delivery of mesenchymal stem cells to injured vasculature in the rabbit carotid artery produces a dysfunctional endothelium'. Tissue Engineering, 16 (5):1657-1665 [DOI] [Details]
(2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'
McMahon SS, Albermann S, Rooney GE, Shaw G, Garcia Y, Sweeney E, Hynes J, Dockery P, O'Brien T, Windebank AJ, Allsopp TE, Barry FP (2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'. Cytotherapy, 12 (3):313-325 [DOI] [Details]
(2010) 'Lentiviral vector-mediated knockdown of the NG2 [corrected] proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar'
Donnelly EM, Strappe PM, McGinley LM, Madigan NN, Geurts E, Rooney GE, Windebank AJ, Fraher J, Dockery P, O'Brien T, McMahon SS (2010) 'Lentiviral vector-mediated knockdown of the NG2 [corrected] proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar'. Journal Of Gene Medicine, 12 (11):863-872 [DOI] [Details]
(2010) 'Engraftment, Migration and Differentiation of Neural Stem Cells in Contused Rat Spinal Cord'
McMahon, S. S., Albermann, S., Garcia, Y., Hynes, J., Dockery, P., Rooney, G.E., Shaw, G., O'Brien, T., Windebank, A. J., Allsopp, T.E. and Barry, F. P. (2010) 'Engraftment, Migration and Differentiation of Neural Stem Cells in Contused Rat Spinal Cord'. Cytotherapy, [Details]
(2010) 'HPLC Purification of Adenoviral Vectors'
Eglon, M,McGrath, B,O'Brien, T,Armstrong, D (2010) 'HPLC Purification of Adenoviral Vectors'. Methods Mol Biol, 594 :395-408 [DOI] [Details]
(2010) 'Generation of Antioxidant Adenovirus Gene Transfer Vectors Encoding CuZnSOD, MnSOD, and Catalase'
Duffy, AM,O'Brien, T,McMahon, JM,Armstrong, D (2010) 'Generation of Antioxidant Adenovirus Gene Transfer Vectors Encoding CuZnSOD, MnSOD, and Catalase'. Methods Mol Biol, 594 :381-393 [DOI] [Details]
(2010) 'Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries'
Whitfield, K,Huemer, KH,Winter, D,Thirstrup, S,Libersa, C,Barraud, B,Kubiak, C,Stankovski, L,Grahlert, X,Dreier, G,Geismann, S,Kuchinke, W,Strenge-Hesse, A,Temesvari, Z,Blasko, G,Kardos, G,O'Brien, T,Cooney, M,Gaynor, S,Schieppati, A,Serrano, M,de Andres, F,Sanz, N,Hernandez, R,Kreis, G,Asker-Hagelberg, C,Johansson, H,Asghar, A,Husson, JM,Demotes, J,Gluud, C (2010) 'Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries'. Trials, 11 [DOI] [Details]
(2010) 'General practitioners' attitudes and preparedness towards Clinical Decision Support in e-Prescribing (CDS-eP) adoption in the West of Ireland: a cross sectional study'
Hor, CP,O'Donnell, JM,Murphy, AW,O'Brien, T,Kropmans, TJB (2010) 'General practitioners' attitudes and preparedness towards Clinical Decision Support in e-Prescribing (CDS-eP) adoption in the West of Ireland: a cross sectional study'. BMC Medical Informatics And Decision Making, 10 [DOI] [Details]
(2010) 'Enhanced lipoplex-mediated gene expression in mesenchymal stem cells using reiterated nuclear localization sequence peptides'
Hoare, M,Greiser, U,Schu, S,Mashayekhi, K,Aydogan, E,Murphy, M,Barry, F,Ritter, T,O'Brien, T (2010) 'Enhanced lipoplex-mediated gene expression in mesenchymal stem cells using reiterated nuclear localization sequence peptides'. Journal Of Gene Medicine, 12 :207-218 [DOI] [Details]
(2010) 'Lentiviral vector-mediated knockdown of the neuroglycan 2 proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar'
Donnelly, EM,Strappe, PM,McGinley, LM,Madigan, NN,Geurts, E,Rooney, GE,Windebank, AJ,Fraher, J,Dockery, P,O'Brien, T,McMahon, SS (2010) 'Lentiviral vector-mediated knockdown of the neuroglycan 2 proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar'. Journal Of Gene Medicine, 12 :863-872 [DOI] [Details]
(2010) 'Bolus Delivery of Mesenchymal Stem Cells to Injured Vasculature in the Rabbit Carotid Artery Produces a Dysfunctional Endothelium'
O'Shea, CA,Hynes, SO,Shaw, G,Coen, BA,Hynes, AC,McMahon, J,Murphy, M,Barry, F,O'Brien, T (2010) 'Bolus Delivery of Mesenchymal Stem Cells to Injured Vasculature in the Rabbit Carotid Artery Produces a Dysfunctional Endothelium'. Tissue Engineering Part A, 16 :1657-1665 [DOI] [Details]
(2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'
Martin, FT,Dwyer, RM,Kelly, J,Khan, S,Murphy, JM,Curran, C,Miller, N,Hennessy, E,Dockery, P,Barry, FP,O'Brien, T,Kerin, MJ (2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'. Breast Cancer Research And Treatment, 124 :317-326 [DOI] [Details]
(2010) 'Translation of science to surgery LINKING EMERGING CONCEPTS IN BIOLOGICAL CARTILAGE REPAIR TO SURGICAL INTERVENTION'
Moran, CJ,Shannon, FJ,Barry, FP,O'Byrne, JM,O'Brien, T,Curtin, W (2010) 'Translation of science to surgery LINKING EMERGING CONCEPTS IN BIOLOGICAL CARTILAGE REPAIR TO SURGICAL INTERVENTION'. Journal Of Bone And Joint Surgery-British Volume, 92B :1195-1202 [DOI] [Details]
(2010) 'Mesenchymal Stem Cells Overexpressing Ephrin-B2 Rapidly Adopt an Early Endothelial Phenotype with Simultaneous Reduction of Osteogenic Potential'
Duffy, GP,D'Arcy, S,Ahsan, T,Nerem, RM,O'Brien, T,Barry, F (2010) 'Mesenchymal Stem Cells Overexpressing Ephrin-B2 Rapidly Adopt an Early Endothelial Phenotype with Simultaneous Reduction of Osteogenic Potential'. Tissue Engineering Part A, 16 :2755-2768 [DOI] [Details]
(2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'
McMahon, SS,Albermann, S,Rooney, GE,Shaw, G,Garcia, Y,Sweeney, E,Hynes, J,Dockery, P,O'Brien, T,Windebank, AJ,Allsopp, TE,Barry, FP (2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'. Cytotherapy, 12 :313-325 [DOI] [Details]
(2010) 'Introduction to Series on Mesenchymal Stromal (Stem) Cells-MSCs'
O'Brien T, Barry F. (2010) 'Introduction to Series on Mesenchymal Stromal (Stem) Cells-MSCs'. Hum Gene Ther Impact Factor 4.2, 21 (9):1037-1038 [DOI] [Details]
(2010) 'Genetically Modified Mesenchymal Stem Cells and Their Clinical Potential in Acute Cardiovascular Disease'
Griffin, M., Greiser, U., Barry, F., O'Brien, T., & Ritter, T. (2010) 'Genetically Modified Mesenchymal Stem Cells and Their Clinical Potential in Acute Cardiovascular Disease'. Discovery Medicine, 9 (46):219-223 [ARAN Link] [Details]
(2010) 'Mesenchymal stem cells overexpressing ephrin b2 rapidly adopt an early endothelial phenotype with simultaneous reduction of osteogenic potential'
Duffy GP, D'Arcy S, Ahsan T, Nerem RM, O'Brien T, Barry F (2010) 'Mesenchymal stem cells overexpressing ephrin b2 rapidly adopt an early endothelial phenotype with simultaneous reduction of osteogenic potential'. Tissue Eng Part A, 16 (9):2755-2768 [DOI] [Details]
(2010) 'General practitioners' attitudes and preparedness towards Clinical Decision Support in e-Prescribing (CDS-eP) adoption in the West of Ireland: a cross sectional study'
Hor CP, O'Donnell JM, Murphy AW, O'Brien T, Kropmans TJ (2010) 'General practitioners' attitudes and preparedness towards Clinical Decision Support in e-Prescribing (CDS-eP) adoption in the West of Ireland: a cross sectional study'. Medical Informatics, 10 [DOI] [Details]
(2010) 'Liposomal Gene Delivery Mediated by Tissue-engineered Scaffolds'
Kulkarni, M., Greiser, U., O’Brien, T. and Pandit, A. (2010) 'Liposomal Gene Delivery Mediated by Tissue-engineered Scaffolds'. Trends In Biotechnology, 28 (1):28-36 [Details]
(2010) ''Non-viral Gene Therapy for Myocardial Engineering'
Holladay, C.A., Pandit, A. and O'Brien, T. (2010) ''Non-viral Gene Therapy for Myocardial Engineering'. Wire'S Nanomedicine & Nanobiotechnology, 2 (3):232-248 [Details]
(2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'
Dwyer RM, Khan S, Barry FP, O'Brien T and Kerin MJ (2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'. Stem Cell Research And Therapy, 1 (3) [Details]
(2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)''
Martin FT, Dwyer RM, Kelly J, Khan S, Murphy JM, Curran C, Miller N, Hennessy E, Dockery P, Barry FP, O'Brien T, Kerin MJ (2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)''. Breast Cancer Res Treat, 124 (2):317-326 [Details]
(2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'
Martin FT, Dwyer RM, Kelly J, Khan S, Murphy JM, Curran C, Miller N, Hennessy E, Dockery P, Barry FP, O'Brien T, Kerin MJ. (2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'. Breast Cancer Res Treat, 124 (2):317-26 [Details]
(2010) 'Introduction to series on mesenchymal stromal (stem) cells-MSCs'
O'Brien T, Barry F (2010) 'Introduction to series on mesenchymal stromal (stem) cells-MSCs'. Human Gene Therapy, 21 (9):1037-1038 [DOI] [Details]
(2010) 'Mesenchymal stem cells overexpressing ephrin-b2 rapidly adopt an early endothelial phenotype with simultaneous reduction of osteogenic potential'
Duffy GP, D'Arcy S, Ahsan T, Nerem RM, O'Brien T, Barry F (2010) 'Mesenchymal stem cells overexpressing ephrin-b2 rapidly adopt an early endothelial phenotype with simultaneous reduction of osteogenic potential'. Tissue Engineering, 16 (9):2755-2768 [DOI] [Details]
(2010) 'Enhanced lipoplex-mediated gene expression in mesenchymal stem cells using reiterated nuclear localization sequence peptides'
Hoare M, Greiser U, Schu S, Mashayekhi K, Aydogan E, Murphy M, Barry F, Ritter T, O'Brien T (2010) 'Enhanced lipoplex-mediated gene expression in mesenchymal stem cells using reiterated nuclear localization sequence peptides'. Journal Of Gene Medicine, 12 (2):207-218 [DOI] [Details]
(2010) 'General practitioners' attitudes and preparedness towards Clinical Decision Support in e-Prescribing (CDS-eP) adoption in the West of Ireland: a cross sectional study'
Hor, C.P.,O'Donnell, J.M.,Murphy, A.W.,O'Brien, T.,Kropmans, T.J. (2010) 'General practitioners' attitudes and preparedness towards Clinical Decision Support in e-Prescribing (CDS-eP) adoption in the West of Ireland: a cross sectional study'. BMC Med Inform Decis Mak, 10 [Details]
(2009) 'Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN)'
Kubiak, C,de Andres-Trelles, F,Kuchinke, W,Huemer, KH,Thirstrup, S,Whitfield, K,Libersa, C,Barraud, B,Grahlert, X,Dreier, G,Grychtol, R,Temesvari, Z,Blasko, G,Kardos, G,O'Brien, T,Cooney, M,Gaynor, S,Schieppati, A,Sanz, N,Hernandez, R,Asker-Hagelberg, C,Johansson, H,Bourne, S,Byrne, J,Asghar, A,Husson, JM,Gluud, C,Demotes-Mainard, J (2009) 'Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN)'. Trials, 10 [DOI] [Details]
(2009) 'Fibrin scaffold promotes adenoviral gene transfer and controlled vector delivery'
Breen A, Dockery P, O'Brien T, Pandit A (2009) 'Fibrin scaffold promotes adenoviral gene transfer and controlled vector delivery'. Journal Of Biomedical Materials Research Part A, 89 (4):876-884 [DOI] [Details]
(2009) 'Purification of adenoviral vectors by combined anion exchange and gel filtration chromatography'
Eglon, MN,Duffy, AM,O'Brien, T,Strappe, PM (2009) 'Purification of adenoviral vectors by combined anion exchange and gel filtration chromatography'. Journal Of Gene Medicine, 11 :978-989 [DOI] [Details]
(2009) 'Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappa B dependent mechanism'
O'Toole, D,Hassett, P,Contreras, M,Higgins, BD,McKeown, STW,McAuley, DF,O'Brien, T,Laffey, JG (2009) 'Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappa B dependent mechanism'. Thorax, 64 :976-982 [DOI] [Details]
(2009) 'Optimized Aerosol Delivery to a Mechanically Ventilated Rodent'
MacLoughlin, RJ,Higgins, BD,Laffey, JG,O'Brien, T (2009) 'Optimized Aerosol Delivery to a Mechanically Ventilated Rodent'. Journal Of Aerosol Medicine And Pulmonary Drug Delivery, 22 :323-332 [DOI] [Details]
(2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'
Molloy, AP,Martin, FT,Dwyer, RM,Griffin, TP,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'. International Journal Of Cancer, 124 :326-332 [DOI] [Details]
(2009) 'Bone Marrow-Derived Mesenchymal Stem Cells Promote Angiogenic Processes in a Time- and Dose-Dependent Manner In Vitro'
Duffy, GP,Ahsan, T,O'Brien, T,Barry, F,Nerem, RM (2009) 'Bone Marrow-Derived Mesenchymal Stem Cells Promote Angiogenic Processes in a Time- and Dose-Dependent Manner In Vitro'. Tissue Engineering Part A, 15 :2459-2470 [DOI] [Details]
(2009) 'Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord Without Differentiating into Neural Cells'
Rooney, GE,McMahon, SS,Ritter, T,Garcia, Y,Moran, C,Madigan, NN,Flugel, A,Dockery, P,O'Brien, T,Howard, L,Windebank, AJ,Barry, FP (2009) 'Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord Without Differentiating into Neural Cells'. Tissue Engineering Part A, 15 :3049-3059 [DOI] [ARAN Link] [Details]
(2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'
McMahon, SS,Albermann, S,Rooney, GE,Moran, C,Hynes, J,Garcia, Y,Dockery, P,O'Brien, T,Windebank, AJ,Barry, FP (2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'. Journal Of Anatomy, 215 :267-279 [DOI] [Details]
(2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'
Kealy, B,Liew, A,McMahon, JM,Ritter, T,O'Doherty, A,Hoare, M,Greiser, U,Vaughan, EE,Maenz, M,O'Shea, C,Barry, F,O'Brien, T (2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'. Tissue Engineering Part C-Methods, 15 :223-231 [DOI] [Details]
(2009) 'Fibrin scaffold promotes adenoviral gene transfer and controlled vector delivery'
Breen, A,Dockery, P,O'Brien, T,Pandit, A (2009) 'Fibrin scaffold promotes adenoviral gene transfer and controlled vector delivery'. Journal Of Biomedical Materials Research Part A, 89A :876-884 [DOI] [Details]
(2009) 'Fibrin-Lipoplex System for Controlled Topical Delivery of Multiple Genes'
Kulkarni, M,Breen, A,Greiser, U,O'Brien, T,Pandit, A (2009) 'Fibrin-Lipoplex System for Controlled Topical Delivery of Multiple Genes'. Biomacromolecules, 10 :1650-1654 [DOI] [Details]
(2009) 'Elevation of cAMP in Mesenchymal Stem Cells Transiently Upregulates Neural Markers Rather than Inducing Neural Differentiation'
Rooney, GE,Howard, L,O'Brien, T,Windebank, AJ,Barry, FP (2009) 'Elevation of cAMP in Mesenchymal Stem Cells Transiently Upregulates Neural Markers Rather than Inducing Neural Differentiation'. Stem Cells And Development, 18 :387-398 [DOI] [Details]
(2009) 'AAV-2 induces cell mediated immune responses directed against multiple epitopes of the capsid protein VP1'
Madsen D, Cantwell ER, O'Brien T, Johnson PA, Mahon BP (2009) 'AAV-2 induces cell mediated immune responses directed against multiple epitopes of the capsid protein VP1'. J Gen Virol, 90 (pt11):2622-2633 [Details]
(2009) 'Mesenchymal Stem Cell (MSC) secretion of chemokines during differentiation into Osteoblasts, and their potential role in mediating interactions with breast cancer cells'
Molloy AP, Dwyer RM, Martin FT, Griffin TP, Murphy JM, Barry FP, O'Brien T, Kerin MJ (2009) 'Mesenchymal Stem Cell (MSC) secretion of chemokines during differentiation into Osteoblasts, and their potential role in mediating interactions with breast cancer cells'. International Journal of Cancer, 124 (20):326-332 [Details]
(2009) 'Recognition of tropical illness in the returned traveller by healthcare professionals working in an Irish university teaching hospital'
Flaherty, G.,Scott, A.,O'Brien, T. (2009) 'Recognition of tropical illness in the returned traveller by healthcare professionals working in an Irish university teaching hospital'. Tropical Medicine & International Health, 14 :79-80 [Details]
(2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'
Molloy AP, Martin FT, Dwyer RM, Griffin TP, Murphy M, Barry FP, O'Brien T, Kerin MJ. (2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'. International Journal Of Cancer, 124 :326-332 [Details]
(2009) 'IMPLEMENTATION OF ESH-ESC GUIDELINES FOR THE MANAGEMENT OF ARTERIAL HYPERTENSION IN AN IRISH PRIMARY CARE SETTING'
Mieske, K.,Flaherty, G.,O'Brien, T. (2009) 'IMPLEMENTATION OF ESH-ESC GUIDELINES FOR THE MANAGEMENT OF ARTERIAL HYPERTENSION IN AN IRISH PRIMARY CARE SETTING'. Journal of Hypertension, 27 [Details]
(2009) 'Nitric oxide synthase gene therapy: progress and prospects'
O'Connor, D. M.,O'Brien, T. (2009) 'Nitric oxide synthase gene therapy: progress and prospects'. Expert Opinion on Biological Therapy, 9 (77):867-878 [Details]
(2009) 'Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds'
Madigan NN, McMahon S, O'Brien T, Yaszemski MJ, Windebank AJ. (2009) 'Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds'. Respiratory Medicine, 169 (2):183-199 [Details]
(2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'
McMahon SS, Albermann S, Rooney GE, Moran C, Hynes J, Garcia Y, Dockery P, O'Brien T, Windebank AJ, Barry FP. (2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'. Journal Of Anatomy, 215 (3):267-279 [Details]
(2009) 'Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules'
Breen, A., O’Brien, T. and Pandit, A. (2009) 'Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules'. Tissue Engineering Part B-Reviews, 15 (2):201-214 [Details]
(2009) 'Fibrin-lipoplex System for Controlled Topical Delivery of Multiple Genes'
Kulkarni, M., Breen, A. Greiser, U., O’Brien, T. and Pandit, A. (2009) 'Fibrin-lipoplex System for Controlled Topical Delivery of Multiple Genes'. Biomacromolecules, 10 (6):1650-1654 [Details]
(2009) 'Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappaB dependent mechanism'
O'Toole D, Hassett P, Contreras M, Higgins BD, McKeown ST, McAuley DF, O'Brien T, Laffey JG (2009) 'Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappaB dependent mechanism'. Thorax, 64 (11):976-982 [DOI] [Details]
(2009) 'Bone marrow-derived mesenchymal stem cells promote angiogenic processes in a time- and dose-dependent manner in vitro'
Duffy GP, Ahsan T, O'Brien T, Barry F, Nerem RM (2009) 'Bone marrow-derived mesenchymal stem cells promote angiogenic processes in a time- and dose-dependent manner in vitro'. Tissue Engineering, 15 (9):2459-2470 [DOI] [Details]
(2009) 'A matrix reservoir for improved control of non-viral gene delivery'
Holladay C, Keeney M, Greiser U, Murphy M, O'Brien T, Pandit A (2009) 'A matrix reservoir for improved control of non-viral gene delivery'. J Control Release, 136 (3):220-225 [DOI] [Details]
(2009) 'Neurotrophic factor-expressing mesenchymal stem cells survive transplantation into the contused spinal cord without differentiating into neural cells'
Rooney GE, McMahon SS, Ritter T, Garcia Y, Moran C, Madigan NN, Flügel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry FP (2009) 'Neurotrophic factor-expressing mesenchymal stem cells survive transplantation into the contused spinal cord without differentiating into neural cells'. Tissue Engineering, 15 (10):3049-3059 [DOI] [Details]
(2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'
McMahon SS, Albermann S, Rooney GE, Moran C, Hynes J, Garcia Y, Dockery P, O'Brien T, Windebank AJ, Barry FP (2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'. Journal Of Anatomy, 215 (3):267-279 [DOI] [Details]
(2009) 'Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1'
Madsen, D,Cantwell, ER,O'Brien, T,Johnson, PA,Mahon, BP (2009) 'Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1'. Journal Of General Virology, 90 :2622-2633 [DOI] [Details]
(2008) 'Elevation of cAMP Induces Transient Upregulation of Neural Markers in Mesenchymal Stem Cells Cultured in a Defined Element Serum-Free Environment'
Rooney, GE, Howard, L, O' Brien, T, Windebank, AJ, Barry, FP (2008) 'Elevation of cAMP Induces Transient Upregulation of Neural Markers in Mesenchymal Stem Cells Cultured in a Defined Element Serum-Free Environment'. Stem Cells Dev, [Details]
(2008) 'Metabolic flexibility permits MSC survival in an ischemic environment'
Mylotte LA, Duffy AM, Murphy M, O'Brien T, Samali A, Barry F, Szegezdi E (2008) 'Metabolic flexibility permits MSC survival in an ischemic environment'. Stem Cells, 26 (5):1325-1336 [DOI] [Details]
(2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'
Rooney, GE,Moran, C,McMahon, SS,Ritter, T,Maenz, M,Flugel, A,Dockery, P,O'Brien, T,Howard, L,Windebank, AJ,Barry, FP (2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'. Tissue Engineering Part A, 14 :681-690 [DOI] [Details]
(2008) 'Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment'
Mylotte, LA,Duffy, AM,Murphy, M,O'Brien, T,Samali, A,Barry, F,Szegezdi, E (2008) 'Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment'. Stem Cells and Development, 26 :1325-1336 [DOI] [Details]
(2008) 'Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-X-L'
Holohan, C,Szegezdi, E,Ritter, T,O'Brien, T,Samali, A (2008) 'Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-X-L'. Journal Of Cellular And Molecular Medicine, 12 :591-606 [DOI] [Details]
(2008) 'Alferminogene tadenovec, an angiogenic FGF4 gene therapy for coronary artery disease'
Flynn, A,O'Brien, T (2008) 'Alferminogene tadenovec, an angiogenic FGF4 gene therapy for coronary artery disease'. Idrugs, 11 :283-293 [Details]
(2008) 'Comparative evaluation of viral, nonviral and physical methods of gene delivery to normal and transformed lung epithelial cells'
Gilbert, JL,Purcell, J,Strappe, P,McCabe, M,O'Brien, T,O'Dea, S (2008) 'Comparative evaluation of viral, nonviral and physical methods of gene delivery to normal and transformed lung epithelial cells'. Anti-Cancer Drugs, 19 :783-788 [DOI] [Details]
(2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'
Sen, S,Conroy, S,Hynes, SO,McMahon, J,O'Doherty, A,Bartlett, JS,Akhtar, Y,Adegbola, T,Connolly, CE,Sultan, S,Barry, F,Katusic, ZS,O'Brien, T (2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'. Journal Of Gene Medicine, 10 :143-151 [DOI] [Details]
(2008) 'Evidence suggests rigid aortic grafts increase systolic blood pressure: Results of a preliminary study'
O'Brien, T,Morris, L,McGloughlin, T (2008) 'Evidence suggests rigid aortic grafts increase systolic blood pressure: Results of a preliminary study'. Medical Engineering & Physics, 30 :109-115 [DOI] [Details]
(2008) 'Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model'
Mohr, A,Lyons, M,Deedigan, L,Harte, T,Shaw, G,Howard, L,Barry, F,O'Brien, T,Zwacka, R (2008) 'Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model'. Journal Of Cellular And Molecular Medicine, 12 :2628-2643 [DOI] [Details]
(2008) 'Gene-eluting stents: Adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis'
Sharif, F,Hynes, SO,Cooney, R,Howard, L,McMahon, J,Daly, K,Crowley, J,Barry, F,O'Brien, T (2008) 'Gene-eluting stents: Adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis'. Molecular Therapy, 16 :1674-1680 [DOI] [Details]
(2008) 'Assessment of Wound Healing in the Alloxan-Induced Diabetic Rabbit Ear Model'
Breen, A,Mc Redmond, G,Dockery, R,O'Brien, T,Pandit, A (2008) 'Assessment of Wound Healing in the Alloxan-Induced Diabetic Rabbit Ear Model'. J Invest Surg, 21 :261-269 [DOI] [Details]
(2008) 'The use of therapeutic gene eNOS delivered via a fibrin scaffold enhances wound healing in a compromised wound model'
Breen, AM,Dockery, P,O'Brien, T,Pandit, AS (2008) 'The use of therapeutic gene eNOS delivered via a fibrin scaffold enhances wound healing in a compromised wound model'. Biomaterials, 29 :3143-3151 [DOI] [Details]
(2008) 'Gene Eluting Stents: Adenoviral-Mediated Delivery of eNOS to the Blood Vessel Wall Accelerates Re-Endothelialization and Inhibits Restenosis'
Sharif F, Hynes SO, Cooney R, Howard L, McMahon J, Daly K, Crowley J, Barry F, O'Brien, T (2008) 'Gene Eluting Stents: Adenoviral-Mediated Delivery of eNOS to the Blood Vessel Wall Accelerates Re-Endothelialization and Inhibits Restenosis'. Mol Ther, 16 (10):1674-1680 [DOI] [Details]
(2008) 'Genetic engineering of the blood vessel wall to improve nitric oxide bioavailability'
O'Brien, T (2008) 'Genetic engineering of the blood vessel wall to improve nitric oxide bioavailability'. Bio-Medical Materials And Engineering, 18 :301-302 [DOI] [Details]
(2008) 'The Use of Therapeutic Gene eNOS Delivered via a Fibrin Scaffold Enhances Wound Healing in a Compromised Wound Model'
Breen, A.M., Dockery P., O' Brien, T. and Pandit, A.S. (2008) 'The Use of Therapeutic Gene eNOS Delivered via a Fibrin Scaffold Enhances Wound Healing in a Compromised Wound Model'. Biomaterials, 29 (21):3143-3151 [Details]
(2008) 'Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model'
Mohr A, Lyons M, Deedigan L, Harte T, Shaw G, Howard L, Barry F, O'Brien T, Zwacka R (2008) 'Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model'. Journal Of Cellular And Molecular Medicine, 12 (6B):2628-2643 [DOI] [Details]
(2008) 'Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment'
Mylotte LA, Duffy AM, Murphy M, O'Brien T, Samali A, Barry F, Szegezdi E (2008) 'Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment'. Stem Cells and Development, 26 (5):1325-1336 [DOI] [Details]
(2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'
Rooney GE, Moran C, McMahon SS, Ritter T, Maenz M, Flügel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry FP (2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'. Tissue Engineering, 14 (5):681-690 [DOI] [Details]
(2008) 'The use of therapeutic gene eNOS delivered via a fibrin scaffold enhances wound healing in a compromised wound model'
Breen AM, Dockery P, O'Brien T, Pandit AS (2008) 'The use of therapeutic gene eNOS delivered via a fibrin scaffold enhances wound healing in a compromised wound model'. Biomaterials, 29 (21):3143-3151 [DOI] [Details]
(2008) 'Assessment of wound healing in the alloxan-induced diabetic rabbit ear model'
Breen A, Mc Redmond G, Dockery P, O'Brien T, Pandit A (2008) 'Assessment of wound healing in the alloxan-induced diabetic rabbit ear model'. J Invest Surg, 21 (5):261-269 [DOI] [Details]
(2007) 'beta cell cytoprotection using lentiviral vector-based iNOS-specific shRNA delivery'
McCabe, C,O'Brien, T (2007) 'beta cell cytoprotection using lentiviral vector-based iNOS-specific shRNA delivery'. Biochemical And Biophysical Research Communications, 357 :75-80 [DOI] [Details]
(2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE-/- mice aortas'
Reeve JL, Stenson-Cox C, O'Doherty A, Pörn-Ares I, Ares M, O'Brien T, Samali A (2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE-/- mice aortas'. Biochem, 356 (3):681-686 [DOI] [Details]
(2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE(-/-) mice aortas'
Reeve, JLV,Stenson-Cox, C,O'Doherty, A,Porn-Ares, I,Ares, M,O'Brien, T,Samali, A (2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE(-/-) mice aortas'. Biochemical And Biophysical Research Communications, 356 :681-686 [DOI] [Details]
(2007) 'Adeno-associated viral vector transduction of human mesenchymal stem cells'
Stender, S,Murphy, M,O'Brien, T,Stengaard, C,Ulrich-Vinther, M,Soballe, K,Barry, F (2007) 'Adeno-associated viral vector transduction of human mesenchymal stem cells'. European Cells & Materials, 13 :93-99 [Details]
(2007) 'Effect of gene delivery of NOS isoforms on intimal hyperplasia and endothelial regeneration after balloon injury'
Cooney, R,Hynes, SO,Sharif, F,Howard, L,O'Brien, T (2007) 'Effect of gene delivery of NOS isoforms on intimal hyperplasia and endothelial regeneration after balloon injury'. Gene Therapy, 14 :396-404 [DOI] [Details]
(2007) 'Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-X-L'
Reeve, JLV,Szegezdi, E,Logue, SE,Chonghaile, TN,O'Brien, T,Ritter, T,Samali, A (2007) 'Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-X-L'. Journal Of Cellular And Molecular Medicine, 11 :509-520 [DOI] [Details]
(2007) 'Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells'
Dwyer, RM,Potter-Beirne, SM,Harrington, KA,Lowery, AJ,Hennessy, E,Murphy, JM,Barry, FP,O'Brien, T,Kerin, MJ (2007) 'Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells'. Clinical Cancer Research, 13 :5020-5027 [DOI] [Details]
(2007) 'Recombinant adenoviral gene transfer does not affect cardiac allograft vasculopathy'
Rao, VP, Branzoli SE, Miyagi N, O'Brien, T, Tazelaar HD, Russell SJ, McGregor CG (2007) 'Recombinant adenoviral gene transfer does not affect cardiac allograft vasculopathy'. J Heart Lung Transplant, 26 (12):1281-1285 [Details]
(2007) 'Beta cell cytoprotection using lentiviral vector-based iNOS-specific shRNA delivery'
McCabe C, O'Brien T (2007) 'Beta cell cytoprotection using lentiviral vector-based iNOS-specific shRNA delivery'. Biochem Biophys Res Commun, 357 (1):75-80 [DOI] [Details]
(2007) 'The rational design of beta cell cytoprotective gene transfer strategies: Targeting deleterious NOS expression'
McCabe, C,O'Brien, T (2007) 'The rational design of beta cell cytoprotective gene transfer strategies: Targeting deleterious NOS expression'. Molecular Biotechnology, :38-47 [DOI] [Details]
(2007) 'Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells'
Dwyer, R. M., Potter-Beirne, S. M., Harrington, K. A., Lowery, A. J., Hennessy, E., Murphy, J. M., Barry, F. P., O'Brien, T. & Kerin, M. J. (2007) 'Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells'. Clinical Cancer Research, 13 (17):5020-5027 [Details]
(2007) 'UC blood-derived mesenchymal stromal cells: an overview'
Flynn A, Barry F, O'Brien T (2007) 'UC blood-derived mesenchymal stromal cells: an overview'. Cytotherapy, 9 (8):717-726 [DOI] [Details]
(2007) 'Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells'
Dwyer RM, Potter-Beirne SM, Harrington KA, Lowery AJ, Hennessy E, Murphy JM, Barry FP, O'Brien T, Kerin MJ (2007) 'Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells'. Cancer Research, 13 (17):5020-5027 [DOI] [Details]
(2007) 'Adeno-associated viral vector transduction of human mesenchymal stem cells'
Stender S, Murphy M, O'Brien T, Stengaard C, Ulrich-Vinther M, Søballe K, Barry F (2007) 'Adeno-associated viral vector transduction of human mesenchymal stem cells'. Cell, 13 :93-1 [Details]
(2007) 'Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL'
Reeve JL, Szegezdi E, Logue SE, Ní Chonghaile T, O'Brien T, Ritter T, Samali A (2007) 'Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL'. Journal Of Cellular And Molecular Medicine, 11 (3):509-520 [DOI] [Details]
(2007) 'Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL'
Reeve JL;Szegezdi E;Logue SE;Ní Chonghaile T;O'Brien T;Ritter T;Samali A; (2007) 'Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL'. Journal Of Cellular And Molecular Medicine, 11 (3) [DOI] [Details]
(2006) 'Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors'
McMahon JM, Conroy S, Lyons M, Greiser U, O'shea C, Strappe P, Howard L, Murphy M, Barry F, O'Brien T (2006) 'Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors'. Stem Cells and Development, 15 (1):87-96 [DOI] [Details]
(2006) 'ER stress contributes to ischemia-induced cardiomyocyte apoptosis'
Szegezdi E, Duffy A, O'Mahoney ME, Logue SE, Mylotte LA, O'brien T, Samali A (2006) 'ER stress contributes to ischemia-induced cardiomyocyte apoptosis'. Biochem, 349 (4):1406-1411 [DOI] [Details]
(2006) 'Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins'
Duffy A, Liew A, O'Sullivan J, Avalos G, Samali A, O'Brien T (2006) 'Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins'. Endothelium, 13 (1):9-16 [DOI] [Details]
(2006) 'beta cell cytoprotective strategies: establishing the relative roles for iNOS and ROS'
McCabe C, Samali A, O'brien T (2006) 'beta cell cytoprotective strategies: establishing the relative roles for iNOS and ROS'. Biochem, 342 (4):1240-1248 [DOI] [Details]
(2006) 'Cytoprotection of beta cells: rational gene transfer strategies'
McCabe C, Samali A, O'Brien T (2006) 'Cytoprotection of beta cells: rational gene transfer strategies'. Diabetes, 22 (3):241-252 [DOI] [Details]
(2006) 'Gene-eluting stents: comparison of adenoviral and adeno- associated viral gene delivery to the blood vessel wall in vivo'
Sharif F, Hynes SO, McMahon J, Cooney R, Conroy S, Dockery P, Duffy G, Daly K, Crowley J, Bartlett JS, O'Brien T (2006) 'Gene-eluting stents: comparison of adenoviral and adeno- associated viral gene delivery to the blood vessel wall in vivo'. Human Gene Therapy, 17 (7):741-750 [DOI] [Details]
(2006) 'ER stress contributes to ischemia-induced cardiomyocyte apoptosis'
Szegezdi E;Duffy A;O'Mahoney ME;Logue SE;Mylotte LA;O'brien T;Samali A; (2006) 'ER stress contributes to ischemia-induced cardiomyocyte apoptosis'. Biochemical And Biophysical Research Communications, 349 (4) [DOI] [Details]
(2006) 'Vitamin D insufficiency in older female community-dwelling acute hospital admissions and the response to supplementation'
DeLappe, E,McGreevy, C,ni Chadhain, N,Grimes, H,O'Brien, T,Mulkerrin, E (2006) 'Vitamin D insufficiency in older female community-dwelling acute hospital admissions and the response to supplementation'. European Journal Of Clinical Nutrition, 60 :1009-1015 [DOI] [Details]
(2006) 'Gene-eluting stents: Comparison of adenoviral and adeno-associated viral gene delivery to the blood vessel wall in vivo'
Sharif, F,Hynes, SO,McMahon, J,Cooney, R,Conroy, S,Dockery, P,Duffy, G,Daly, K,Crowley, J,Bartlett, JS,O'Brien, T (2006) 'Gene-eluting stents: Comparison of adenoviral and adeno-associated viral gene delivery to the blood vessel wall in vivo'. Human Gene Therapy, 17 :741-750 [Details]
(2006) 'Optimization of a fibrin scaffold for sustained release of an adenoviral gene vector'
Breen, A,Strappe, P,Kumar, A,O'Brien, T,Pandit, A (2006) 'Optimization of a fibrin scaffold for sustained release of an adenoviral gene vector'. Journal Of Biomedical Materials Research Part A, 78A :702-708 [DOI] [Details]
(2006) 'ER stress contributes to ischemia-induced cardiomyocyte apoptosis'
Szegezdi, E,Duffy, A,O'Mahoney, ME,Logue, SE,Mylotte, LA,O'Brien, T,Samali, A (2006) 'ER stress contributes to ischemia-induced cardiomyocyte apoptosis'. Biochemical And Biophysical Research Communications, 349 :1406-1411 [DOI] [Details]
(2006) 'Adenoviral-mediated gene transfer of nitric oxide synthase isoforms and vascular cell proliferation'
Cooney, R,Hynes, SO,Duffy, AM,Sharif, F,O'Brien, T (2006) 'Adenoviral-mediated gene transfer of nitric oxide synthase isoforms and vascular cell proliferation'. Journal Of Vascular Research, 43 :462-472 [DOI] [Details]
(2006) 'Gene transfer into rat mesenchymal stem cells: A comparative study of viral and nonviral vectors'
McMahon, JM,Conroy, S,Lyons, M,Greiser, U,O'Shea, C,Strappe, P,Howard, L,Murphy, M,Barry, F,O'Brien, T (2006) 'Gene transfer into rat mesenchymal stem cells: A comparative study of viral and nonviral vectors'. Stem Cells And Development, 15 :87-96 [Details]
(2006) 'beta cell cytoprotective strategies: Establishing the relative roles for iNOS and ROS'
McCabe, C,Samali, A,O'Brien, T (2006) 'beta cell cytoprotective strategies: Establishing the relative roles for iNOS and ROS'. Biochemical And Biophysical Research Communications, 342 :1240-1248 [DOI] [Details]
(2006) 'Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins'
Duffy, A,Liew, A,O'Sullivan, J,Avalos, G,Samali, A,O'Brien, T (2006) 'Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins'. Endothelium-Journal Of Endothelial Cell Research, 13 :9-16 [DOI] [Details]
(2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations'
O'Brien, T. (2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations'. Bioessays. 2006 Mar;28(3):261-70, 28 (3):261-270 [Details]
(2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations. Bioessays'
Liew A, Barry F, O'Brien T (2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations. Bioessays'. Bioessays, 28 (3):261-270 [Details]
(2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations'
Liew, A,Barry, F,O'Brien, T (2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations'. Bioessays, 28 :261-270 [DOI] [Details]
(2006) 'Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors'
McMahon, JM,Conroy, S,Lyons, M,Greiser, U,O'shea, C,Strappe, P,Howard, L,Murphy, M,Barry, F,O'brien, T (2006) 'Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors'. Stem Cells Dev, 15 (11):87-96 [Details]
(2005) 'Purification of adenovirus and adeno-associated virus: Comparison of novel membrane-based technology to conventional techniques'
Duffy, AM,O'Doherty, AM,O'Brien, T,Strappe, PM (2005) 'Purification of adenovirus and adeno-associated virus: Comparison of novel membrane-based technology to conventional techniques'. Gene Therapy, :62-72 [DOI] [Details]
(2005) 'Don’t loose Heart: Therapeutic value of anti-apoptotic strategies in the treatment of cardiovascular disease'
Reeve J., Duffy A., O'Brien T., Samali A. (2005) 'Don’t loose Heart: Therapeutic value of anti-apoptotic strategies in the treatment of cardiovascular disease'. J. Cell. Mol. Med, :609-622 [Details]
(2005) 'Don't lose heart--therapeutic value of apoptosis prevention in the treatment of cardiovascular disease'
Reeve JL, Duffy AM, O'Brien T, Samali A (2005) 'Don't lose heart--therapeutic value of apoptosis prevention in the treatment of cardiovascular disease'. Journal Of Cellular And Molecular Medicine, 9 (3):609-622 [Details]
(2005) 'Mesenchymal stem cell transplantation for tissue repair'
Flaherty, G, Bell, M, Dunne, F, O'Brien, T. (2005) 'Mesenchymal stem cell transplantation for tissue repair'. Sem Plast Surg 19:229-239, 19 :229-239 [Details]
(2005) 'The malady of ascent - an overview of high altitude illness'
Liew A, Barry F, O'Brien T (2005) 'The malady of ascent - an overview of high altitude illness'. Modern Medicine 35 No.2 Feb 2005: 37- 41, 35 (2):37-41 [Details]
(2005) 'Don't Lose Heart - Therapeutic Value of Apoptosis Prevention in the Treatment of Cardiovascular Disease'
McCabe C, Samali A, O'Brien T. (2005) 'Don't Lose Heart - Therapeutic Value of Apoptosis Prevention in the Treatment of Cardiovascular Disease'. Journal Of Cellular And Molecular Medicine, 9 (3):609-622 [Details]
(2004) 'In vivo expression and function of recombinant GTPCH I in the rabbit carotid artery'
Hynes, SO,Smith, LA,Richardson, DM,Kovesdi, I,O'Brien, T,Katusic, ZS (2004) 'In vivo expression and function of recombinant GTPCH I in the rabbit carotid artery'. American Journal Of Physiology-Heart And Circulatory Physiology, 286 :570-574 [DOI] [Details]
(2003) 'A direct mechanical method for accurate and efficient adenoviral vector delivery to tissues'
Khurana V, O'Brien T, Katusic ZS (2003) 'A direct mechanical method for accurate and efficient adenoviral vector delivery to tissues'. Gene Therapy, 10 :443-452 [Details]
(2003) 'In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits'
Zanetti, M,d'Uscio, LV,Kovesdi, I,Katusic, ZS,O'Brien, T (2003) 'In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits'. Stroke, 34 :1293-1298 [DOI] [Details]
(2003) 'Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation'
Abunasra HJ, Smokenski RT, Yap J, Sheppard M, O'Brien T, Yacoub MH (2003) 'Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation'. J Thorac Cardiovasc Surg, 125 (5):998-1006 [Details]
(2002) 'Gene Transfer to Cornary Artery Bypass Conduits'
Chui, C, O'Brien, T, Schaff, HV (2002) 'Gene Transfer to Cornary Artery Bypass Conduits'. Ann Thorac Surg discussion 1166, 74 (4):1161-1166 [Details]
(2002) 'Adenoviral-mediated overexpression of catalase inhibits endothelial cell proliferation'
Zanetti, M,Katusic, ZS,O'Brien, T (2002) 'Adenoviral-mediated overexpression of catalase inhibits endothelial cell proliferation'. American Journal Of Physiology-Heart And Circulatory Physiology, 283 :2620-2626 [DOI] [Details]
(2002) 'Inhibitory effect of recombinant iNOS gene expression on vasomotor function of canine basilar artery'
Eguchi, D,D'Uscio, LV,Wambi, C,Weiler, D,Kovesdi, I,O'Brien, T,Katusic, ZS (2002) 'Inhibitory effect of recombinant iNOS gene expression on vasomotor function of canine basilar artery'. American Journal Of Physiology-Heart And Circulatory Physiology, 283 :2560-2566 [DOI] [Details]
(2002) 'Dietary antioxidants preserve endothelium dependent vasorelaxation in overfed rats'
Sato, J,O'Brien, T,Katusic, ZS,Fu, AZ,Nygren, J,Singh, R,Nair, KS (2002) 'Dietary antioxidants preserve endothelium dependent vasorelaxation in overfed rats'. Atherosclerosis, 161 :327-333 [DOI] [Details]
(2002) 'Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm'
Khurana VG, Smith LA, Baker TA, Eguchi D, O'Brien T, Katusic ZS (2002) 'Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm'. Stroke, 33 :782-789 [Details]
(2002) 'Diabetic mastopathy or sclerosing lymphocytic lobulitis is a breast disorder specific for type 1 diabetes mellitus'
Kudva YC, O'Brien T, Crotty TB (2002) 'Diabetic mastopathy or sclerosing lymphocytic lobulitis is a breast disorder specific for type 1 diabetes mellitus'. Diabetes Care, 25 :121-126 [Details]
(2002) 'Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries'
Akiyama M, Eguchi D, Weiler D, O'Brien T, Kovesdi I, Scotland RS, Sessa WC, Katusic ZS (2002) 'Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries'. Stroke, 33 :1071-1076 [Details]
(2001) 'Gene transfer of superoxide dismutase isoforms reverses endothelial dysfunction in diabetic rabbit aorta'
Zanetti M, Sato J, Katusic ZS, O'Brien T (2001) 'Gene transfer of superoxide dismutase isoforms reverses endothelial dysfunction in diabetic rabbit aorta'. Am J Physiol Heart Circ Physiol, 280 :h2516-h2523 [Details]
(2001) 'Superoxide anions and endothelial cell proliferation in normoglycemia and hyperglycemia'
Zanetti M, Zwacka RM, Engelhardt JF, Katusic ZS, O'Brien T (2001) 'Superoxide anions and endothelial cell proliferation in normoglycemia and hyperglycemia'. Arteriosclerosis, Thrombosis and Vascular Biology, 21 :195-200 [Details]
(2001) 'Low-density lipoprotein apheresis for the treatment of refractory hyperlipidemia'
Vella, A,Pineda, AA,O'Brien, T (2001) 'Low-density lipoprotein apheresis for the treatment of refractory hyperlipidemia'. Mayo Clinic Proceedings, 76 :1039-1046 [Details]
(2001) 'Efficacy of adenoviral gene transfer of Superoxide Dismutase and Nitric Oxide Synthase in reducing ischemia reperfusion injury'
Abunasra HJ, Smolenski RT, Morrison K, Yap J, Sheppard M, O'Brien T, K Suzuki, Jayakumar J, Yacoub MH (2001) 'Efficacy of adenoviral gene transfer of Superoxide Dismutase and Nitric Oxide Synthase in reducing ischemia reperfusion injury'. Eur J Cardiothorac Surg, 20 :153-158 [Details]
(2001) 'The effects of CTLA-4Ig on acute lung allograft rejection – a comparison of intrabronchial gene therapy with systemic administration of protein'
Ugurlu MM, Griffin MD, O'Brien T, Tazelaar HD, Miller VM, McGregor CGA (2001) 'The effects of CTLA-4Ig on acute lung allograft rejection – a comparison of intrabronchial gene therapy with systemic administration of protein'. Transplantation, 71 :1867-1871 [Details]
(2001) 'Dietary antioxidants preserve endothelium dependent vasorelaxation in rats fed a high fat diet'
Sato J, O'Brien T, Katusic ZS, Fu A, Nygren JA, Singh R, Nair KS (2001) 'Dietary antioxidants preserve endothelium dependent vasorelaxation in rats fed a high fat diet'. Atherosclerosis, 161 :327-333 [Details]
(2001) 'Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in the absence but not in the presence of atherosclerotic plaque'
Zanetti M, Sato J, Jost CJ, Gloviczki P, Katusic ZS, O'Brien T (2001) 'Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in the absence but not in the presence of atherosclerotic plaque'. Human Gene Therapy, 12 :1407-1416 [Details]
(2001) 'Effects of immunosuppressants on osteoprotegerin and osteoprotegerin-ligand production by human osteoblastic and coronary artery smooth muscle cells: Potential implications for post-transplant osteoporosis and vascular disease'
Hofbauer LC, Riggs BL, Dunstan CR, Spelsberg TC, O'Brien T, Khosla S (2001) 'Effects of immunosuppressants on osteoprotegerin and osteoprotegerin-ligand production by human osteoblastic and coronary artery smooth muscle cells: Potential implications for post-transplant osteoporosis and vascular disease'. Biochem Biophys Res Comm, 280 (1):334-339 [Details]
(2001) 'Conditions of vector delivery improve efficiency of adenoviral-mediated gene transfer to the transplanted heart'
Yap J, Pellegrini C, O'Brien T, Tazelaar HD, McGregor CGA (2001) 'Conditions of vector delivery improve efficiency of adenoviral-mediated gene transfer to the transplanted heart'. Eur J Cardiothor Surgery, 19 :702-707 [Details]
(2000) 'Highly efficient, ex vivo gene transfer to the transplanted heart by hypothermic perfusion with a low dose of adenoviral vector'
Pellegrini C, Jeppsson A, Taner CB, O'Brien T, Miller VM, Tazelaar HD, McGregor CGA (2000) 'Highly efficient, ex vivo gene transfer to the transplanted heart by hypothermic perfusion with a low dose of adenoviral vector'. J Thor Cardiovasc Surg, 119 :493-500 [Details]
(2000) 'Gene transfer of endothelial nitric oxide synthase to pulmonary allografts: impact on acute rejection'
Jeppsson A, Pellegrini C, O'Brien T, Miller VM, Tazelaar HD, Taner CB, McGregor CG (2000) 'Gene transfer of endothelial nitric oxide synthase to pulmonary allografts: impact on acute rejection'. Transplant International, 13 (1):s591-s596 [Details]
(2000) 'Expression and function of recombinant endothelial nitric oxide synthase in endothelial cells'
Zanetti M, Katusic ZS, O'Brien T (2000) 'Expression and function of recombinant endothelial nitric oxide synthase in endothelial cells'. J Vasc Res, 37 (6):449-456 [Details]
(2000) 'Improved efficiency of gene transfer to the transplanted lung by retrograde vascular gene delivery'
Jeppsson AZ, Pellegrini C, Lee R, O'Brien T, Miller VM, Tazelaar HD, McGregor CGA (2000) 'Improved efficiency of gene transfer to the transplanted lung by retrograde vascular gene delivery'. Transpl Int, 13 :241-246 [Details]
(2000) 'In vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits enhances endothelium-dependent relaxations'
Sato J, Mohacsi T, Noel A, Jost C, Gloviczki P, Mozes G, Katusic ZS, O'Brien T (2000) 'In vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits enhances endothelium-dependent relaxations'. Stroke, 31 :968-975 [Details]
(2000) 'Inhibition of adrenal cell aldosterone synthesis by endogenous nitric oxide production'
Hanke CJ, O'Brien T, Pritchard KA Jr, Campbell WB (2000) 'Inhibition of adrenal cell aldosterone synthesis by endogenous nitric oxide production'. Hypertension, 35 ((1 Part 2 Suppl S)):324-328 [Details]
(2000) 'Familial splenomegaly: Macrophage hypercatabolism of lipoproteins associated with apolipoprotein E mutation'
Nguyen TT, Kruckeberg KE, O'Brien JF, Ji ZS, Karnes PS, Crotty TB, Hay ID, Mahley RW, O'Brien T (2000) 'Familial splenomegaly: Macrophage hypercatabolism of lipoproteins associated with apolipoprotein E mutation'. J Clin Endocrinol Metab, 85 (11):4354-4358 [Details]
(2000) 'Adenovirus-mediated gene transfer to human cerebral arteries'
Khurana VG, Smith LA, Weiler DA, Springett MJ, Meyer FB, Marsh WR, O'Brien T, Katusic ZS (2000) 'Adenovirus-mediated gene transfer to human cerebral arteries'. J Cereb Blood Flow Metab, 20 :1360-1371 [Details]
(2000) 'Surgical treatment of valvular heart disease in patients with acromegaly'
Cable DG, Dearani JA, O'Brien T, Orszulak TA, Puga FJ, Schaff HV (2000) 'Surgical treatment of valvular heart disease in patients with acromegaly'. J Heart Valve Disease, 9 (6):828-831 [Details]
(2000) 'B1 and B2 bradykinin receptors on adventitial fibroblasts of cerebral arteries are coupled to recombinant endothelial nitric oxide synthase'
Tsutsui M, Onoue H, Iida Y, Smith L, O'Brien T, Katusic Z (2000) 'B1 and B2 bradykinin receptors on adventitial fibroblasts of cerebral arteries are coupled to recombinant endothelial nitric oxide synthase'. Am J Physiol Heart Circ, 278 :h367-h372 [Details]
(2000) 'Gene transfer of endothelial nitric oxide synthase improves endothelium-dependent relaxations in aorta from diabetic rabbits'
Zanetti M, Sato J, Katusic Z, O'Brien T (2000) 'Gene transfer of endothelial nitric oxide synthase improves endothelium-dependent relaxations in aorta from diabetic rabbits'. Diabetologia, 43 :340-347 [Details]
(2000) 'Effects of recombinant endothelial nitric oxide synthase gene expression on reactivity of small cerebral arteries'
Tsutsui M, Onoue H, Iida Y, Smith L, O'Brien T, Katusic Z (2000) 'Effects of recombinant endothelial nitric oxide synthase gene expression on reactivity of small cerebral arteries'. Heart Circ Physiol, 278 :h420-h427 [Details]
(2000) 'eNOS gene transfer to vascular smooth muscle cells inhibits cell proliferation via upregulation of p27 and p21 and not apoptosis'
Sato J, Nair KS, Hiddinga J, Eberhardt NE, Fitzpatrick LA, Katusic ZS, O'Brien T (2000) 'eNOS gene transfer to vascular smooth muscle cells inhibits cell proliferation via upregulation of p27 and p21 and not apoptosis'. Cardiovasc Res, 47 (4):697-706 [Details]
(2000) 'Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity'
Balsiger BM, Kennedy FP, Abu-Lebdah H, Collazo-Clavell M, Jensen MD, O'Brien T, Hensrud DD, Dinneen SF, Thompson GB, Que F, Williams DE, Clark MM, Grant JE, Frick MS, Bueller RA, Mai J, Sarr MG (2000) 'Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity'. Mayo Clinic Proceed, 75 (7) [Details]
(1999) 'L-arginine availability is not limiting for nitric oxide generation from recombinant endothelial nitric oxide synthase'
Mohasci T, Mozes G, Sato J, Gloviczki P, Katusic Z, O'Brien T (1999) 'L-arginine availability is not limiting for nitric oxide generation from recombinant endothelial nitric oxide synthase'. J Vasc Res, 36 (6):437-444 [Details]
(1999) 'The role of gene therapy for intimal hyperplasia of bypass grafts'
Cable DG, Caccitolo JA, Caplice N, O'Brien T, Simari RD, Daly RC, Dearani JA, Mullany CJ, Orszulak TA, Schaff HV (1999) 'The role of gene therapy for intimal hyperplasia of bypass grafts'. Circulation, 100: II-392-II-396, 1999 [Details]
(1999) 'Clomiphene-induced severe hypertriglyceridemia and pancreatitis: a case report and review of the literature'
Castro MR, Nguyen TT, O'Brien T (1999) 'Clomiphene-induced severe hypertriglyceridemia and pancreatitis: a case report and review of the literature'. Mayo Clinic Proceedings, 74 :1125-1128 [Details]
(1999) 'Gene transfer of endothelial nitric oxide synthase improves nitric-oxide dependent endothelial function in a hypertensive rat model'
Alexander MY, Brosnan MJ, Hamilton CA, Downie P, Devlin AM, Dowell F, Martina W, Prentice HM, O'Brien T, Dominiczak AF (1999) 'Gene transfer of endothelial nitric oxide synthase improves nitric-oxide dependent endothelial function in a hypertensive rat model'. Cardiovascular Research, 43 :798-807 [Details]
(1999) 'Endothelial regulation of vascular contractions in radial and internal mammary arteries'
Cable D, Caccitolo J, Pfiefer EA, Daly RC, Dearani JA, Mullany CJ, O'Brien T, Orzsulak TA, Schaff HV (1999) 'Endothelial regulation of vascular contractions in radial and internal mammary arteries'. Annals of Thoracic Surgery, 67 :1083-1090 [Details]
(1999) 'Distribution and function of recombinant endothelial nitric oxide synthase in transplanted hearts'
Yap J, O'Brien T, Pellegrini C, Barber DA, Tazelaar HD, Severson SR, Miller VM, McGregor CGA (1999) 'Distribution and function of recombinant endothelial nitric oxide synthase in transplanted hearts'. Cardiovascular Research, 42 (3):720-727 [Details]
(1999) 'Recombinant gene transfer of eNOS augments coronary artery relaxations during hypoxia'
Cable DG, Pompili VJ, O'Brien T, Schaff HV (1999) 'Recombinant gene transfer of eNOS augments coronary artery relaxations during hypoxia'. Circulation, 100: II-335-II-339, 1999 [Details]
(1999) 'Absence of toxicity associated with adenoviral-mediated transfer of b-galactosidase reporter gene to neonatal rat islets in vitro'
O'Brien T, Karlsen AE, Andersen HU, Mandrup-Poulsen T, Nerup J (1999) 'Absence of toxicity associated with adenoviral-mediated transfer of b-galactosidase reporter gene to neonatal rat islets in vitro'. Diabetes Res Clin Pract, 44 :157-163 [Details]
(1999) 'Adventitial expression of recombinant endothelial nitiric oxide synthase gene reverses vasoconstrictor effect of endothelin-1'
Onoue H, Tsutsui M, Smith L, O'Brien T, Katusic ZS (1999) 'Adventitial expression of recombinant endothelial nitiric oxide synthase gene reverses vasoconstrictor effect of endothelin-1'. J Cer Blood Flow Met, 19 :1029-1037 [Details]
(1999) 'H2O2 is required for UVB-induced EGF receptor and downstream signaling pathway activation'
Peus D, Meves A, Vasa RA, Beyerle A, O'Brien T, Pittelkow MR (1999) 'H2O2 is required for UVB-induced EGF receptor and downstream signaling pathway activation'. Free Radical Biology and Medicine, 27 :1197-1202 [Details]
(1998) 'Systemic evaluation of distribution of transgene expression after adenovirus-mediated gene transfer to the transplanted heart'
Pellegrini C, O'Brien T, Yap J, Jeppsson A, Tazelaar HD, McGregor CGA (1998) 'Systemic evaluation of distribution of transgene expression after adenovirus-mediated gene transfer to the transplanted heart'. Transplant International, 11 (5):373-377 [Details]
(1998) 'New approaches to prevention and treatment of vasospasm of radial artery bypass grafts'
Cable DG, Caccitolo JA, Pearson PJ, O'Brien T, Mullany CJ, Daly RC, Orszulak TA, Schaff HV (1998) 'New approaches to prevention and treatment of vasospasm of radial artery bypass grafts'. Circulation, 98:II-15-II-22, 1998 [Details]
(1998) 'Influence of temperature on adenovirus-mediated gene transfer'
Pellegrini C, O'Brien T, Jeppsson A, McGregor CGA (1998) 'Influence of temperature on adenovirus-mediated gene transfer'. European Journal of Cardio-thoracic Surgery, 13 :599-603 [Details]
(1998) 'Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage'
Onoue H, Tsutsui M, Smith L, Stelter A, O'Brien T, Katusic Z (1998) 'Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage'. Stroke, 28 (9):1959-1965 [Details]
(1998) 'Adipocyte macrophage colony-stimulating factor is a mediator of adipose tissue growth'
Levine JA, Jensen MD, Eberhardt NL, O'Brien T (1998) 'Adipocyte macrophage colony-stimulating factor is a mediator of adipose tissue growth'. J Clin Invest, 101 :1557-1564 [Details]
(1998) 'Transbronchial gene transfer of endothelial nitric oxide synthase to transplanted lungs'
Jeppsson A, Pellegrini C, O'Brien T, Miller VM, Tazelaar HD, McGregor C (1998) 'Transbronchial gene transfer of endothelial nitric oxide synthase to transplanted lungs'. Annals of Thoracic Surgery, 66 (2):318-324 [Details]
(1998) 'Adenoviral-mediated gene transfer to human adipocytes in vitro, and human adipose tissue ex vivo and rabbit femoral adipose tissue in vivo'
Levine JA, Eberhardt NL, Jensen MD, O'Brien T (1998) 'Adenoviral-mediated gene transfer to human adipocytes in vitro, and human adipose tissue ex vivo and rabbit femoral adipose tissue in vivo'. Journal of Nutritional Science & Vitaminology, 44 (4):569-572 [Details]
(1998) 'Adventitial expression of recombinant eNOS gene restores NO production in arteries without endothelium'
Tsutsui M, Chen AF, O'Brien T, Crotty TB, Katusic ZS (1998) 'Adventitial expression of recombinant eNOS gene restores NO production in arteries without endothelium'. Arterioscler Thromb Vasc Biol, 18 :1231-1241 [Details]
(1998) 'Adenovirus-mediated gene transfer of macrophage colony stimulating factor to the arterial wall in vivo'
Mozes G, Mohasci T, Gloviczki P, Menawat S, Kullo IJ, Spector D, Taylor J, Crotty T, O'Brien T (1998) 'Adenovirus-mediated gene transfer of macrophage colony stimulating factor to the arterial wall in vivo'. Arterioscler Thromb Vasc Biol, 18 :1157-1163 [Details]
(1998) 'Ex vivo gene transfer of endothelial nitric oxide synthase to atherosclerotic rabbit aortic rings improves relaxations to acetylcholine'
Mozes G, Kullo IJ, Mohasci TG, Cable D, Crotty T, Gloviczki P, Katusic ZS, O'Brien T (1998) 'Ex vivo gene transfer of endothelial nitric oxide synthase to atherosclerotic rabbit aortic rings improves relaxations to acetylcholine'. Atherosclerosis, 141 (2):265-271 [Details]
(1998) 'Gene therapy in lung transplantation: effective gene transfer via the airways'
Jeppsson A, Lee RJ, Pelligrini C, O'Brien T, Tazelaar HD, McGregor CGA (1998) 'Gene therapy in lung transplantation: effective gene transfer via the airways'. Journal of Thoracic and Cardiovascular Surgery, 115 (3):638-643 [Details]
(1998) 'The effect of a high carbohydrate diet on Apo-E poor and Apo-E rich HDL subparticles in NIDDM'
O'Brien T, Nguyen TT, Hodge D, Kottke BA (1998) 'The effect of a high carbohydrate diet on Apo-E poor and Apo-E rich HDL subparticles in NIDDM'. Nutrition, Metabolism and Cardiovascular Diseases, 8 :85-91 [Details]
(1997) 'Expression and function of recombinant endothelial NO synthase in coronary artery smooth muscle cells'
Kullo IJ, Schwartz RS, Pompili V, Tsutsui M, Milstien S, Fitzpatrick LA, Katusic ZS, O'Brien T (1997) 'Expression and function of recombinant endothelial NO synthase in coronary artery smooth muscle cells'. Arteriosclerosis, Thrombosis and Vascular Biology, 17 :2405-2412 [Details]
(1997) 'Recombinant endothelial nitric oxide synthase-transduced human saphenous veins: Gene therapy to augment nitric oxide production in bypass conduits'
Cable DG, O'Brien T, Schaff HV, Pompili VJ (1997) 'Recombinant endothelial nitric oxide synthase-transduced human saphenous veins: Gene therapy to augment nitric oxide production in bypass conduits'. Circulation, 96(Suppl):II-173-8, 1997 :173-178 [Details]
(1997) 'Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries'
Kullo IJ, Mozes G, Schwartz RS, Gloviczki P, Tsutsui M, Katusic ZS, O'Brien T (1997) 'Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries'. Hypertension, 30 :314-320 [Details]
(1997) 'Unusual manifestations of type 1 autoimmune polyendocrinopathy'
O'Sullivan DJ, Cronin C, Buckley D, Mitchell TM, Jenkins DJ, Greally J, O'Brien T. (1997) 'Unusual manifestations of type 1 autoimmune polyendocrinopathy'. IRISH MEDICAL JOURNAL, 90 :100-103 [Details]
(1997) 'Immunosupression prolongs adenoviral mediated transgene expression in cardiac allograft transplantation'
Yap J, O'Brien T, Tazelaar HD, McGregor CGA (1997) 'Immunosupression prolongs adenoviral mediated transgene expression in cardiac allograft transplantation'. Cardiovascular Research, 35 :529-535 [Details]
(1997) 'The effect of the treatment of hypothyroidism and hyperthyroidism on plasma lipids and apolipoproteins AI, AII and E'
O'Brien T, Katz K, Hodge D, Nguyen TT, Hay I, Kottke BA (1997) 'The effect of the treatment of hypothyroidism and hyperthyroidism on plasma lipids and apolipoproteins AI, AII and E'. Clinical Endocrinology, 46 :17-20 [Details]
(1997) 'Effects of in vivo adventitial expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries'
Chen AFY, Jiang SW, Crotty TB, Tsutsui M, Smith LA, O'Brien T, Katusic ZS (1997) 'Effects of in vivo adventitial expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries'. Proc Natl Acad Sci USA, 94 :12568-12573 [Details]
(1997) 'Expression and function of a recombinant endothelial nitric oxide synthase gene in porcine coronary arteries'
Cable DG, O'Brien T, Kullo IJ, Schwartz RS, Schaff HV, Pompili VJ (1997) 'Expression and function of a recombinant endothelial nitric oxide synthase gene in porcine coronary arteries'. Cardiovascular Research, 35 :553-559 [Details]
(1997) 'Expression and function of recombinant endothelial nitric oxide synthase gene in the canine basilar artery'
Chen AF, O'Brien T, Tsutsui M, Kinoshita H, Pompili VJ, Crotty TB, Spector DJ, Katusic ZS (1997) 'Expression and function of recombinant endothelial nitric oxide synthase gene in the canine basilar artery'. Circulation Research, 80 :327-335 [Details]
(1997) 'Adventitial gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries alters vascular reactivity'
Kullo IJ, Mozes G, Schwartz R, Gloviczki P, Crotty TB, Barber DA, Katusic ZS, O'Brien T (1997) 'Adventitial gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries alters vascular reactivity'. Circulation, 96 :2254-2261 [Details]
(1996) 'HDL subparticles and coronary artery disease in NIDDM'
O'Brien T, Nguyen TT, Hallaway BJ, Hodge D, Bailey K, Kottke BA (1996) 'HDL subparticles and coronary artery disease in NIDDM'. Atherosclerosis, 121 :285-291 [Details]
(1996) 'Results of treatment of pituitary disease in multiple endocrine neoplasia type I'
O'Brien T, O'Riordain D, Gharib H, Scheithauer BW, Ebersold M, van Heerden JA (1996) 'Results of treatment of pituitary disease in multiple endocrine neoplasia type I'. Neurosurgery, 39 :273-279 [Details]
(1995) 'Multiple endocrine neoplasia type 2B: More than an endocrine disorder'
O'Riordain DS, O'Brien T, Crotty TB, Gharib H, Grant C, van Heerden JH (1995) 'Multiple endocrine neoplasia type 2B: More than an endocrine disorder'. Surgery, 118 :936-942 [Details]
(1995) 'Diet and Lp(a) in NIDDM'
O'Brien T, Nguyen TT, Bren ND, Kottke BA (1995) 'Diet and Lp(a) in NIDDM'. Nutr Metab Cardiovasc Dis, 5 :17-22 [Details]
(1995) 'The role of lipoprotein A-I and lipoprotein A-I / A-II in predicting the presence of coronary artery disease'
O'Brien T, Nguyen TT, Hallaway BJ, Hodge D, Bailey K, Holmes D, Kottke BA (1995) 'The role of lipoprotein A-I and lipoprotein A-I / A-II in predicting the presence of coronary artery disease'. Arteriosclerosis, Thrombosis and Vascular Biology, 15 :228-231 [Details]
(1994) 'Medullary thyroid carcinoma in multiple endocrine neoplasia types 2a and 2b'
O'Riordain DS, O'Brien T, Weaver, Gharib H, Hay ID, Grant CS, van Heerden JA (1994) 'Medullary thyroid carcinoma in multiple endocrine neoplasia types 2a and 2b'. Surgery, 116 :1017-1023 [Details]
(1994) 'Lipids and Lp(a) lipoprotein levels and coronary artery disease in subjects with non-insulin-dependent diabetes mellitus'
O'Brien T, Nguyen TT, Harrison J, Bailey K, Dyck PJ, Kottke BA (1994) 'Lipids and Lp(a) lipoprotein levels and coronary artery disease in subjects with non-insulin-dependent diabetes mellitus'. Mayo Clinic Proceedings, 69 :430-435 [Details]
(1994) 'Surgical management of insulinoma associated with multiple endocrine neoplasia type 1'
O'Riordain DS, O'Brien T, van Heerden JA, Service FJ, Grant CS (1994) 'Surgical management of insulinoma associated with multiple endocrine neoplasia type 1'. World J of Surgery, 18 :488-494 [Details]
(1993) 'Separation of high-density lipoproteins into apolipoprotein E-poor and apoliprotein E-rich subfractions by fast protein liquid chromatography using a heparin affinity column'
O'Brien T, Buithieu J, Nguyen TT, Klein L, Bren N, Wentworth M, Hallaway BJ, Kottke BA (1993) 'Separation of high-density lipoproteins into apolipoprotein E-poor and apoliprotein E-rich subfractions by fast protein liquid chromatography using a heparin affinity column'. J Chromatogr (Biomedical Applications), 613 :239-246 [Details]
(1993) 'Apolipoprotein A-II levels and coronary artery disease in subjects with and without diabetes: A study with use of a specific radioimmunoassay for apolipoprotein A-II'
Wentworth M, O'Brien T, Rastogi A, Kottke BA (1993) 'Apolipoprotein A-II levels and coronary artery disease in subjects with and without diabetes: A study with use of a specific radioimmunoassay for apolipoprotein A-II'. Mayo Clinic Proceedings, 68 :556-560 [Details]
(1993) 'Surgical management of hyperparathyroidism in multiple endocrine neoplasia syndrome'
O'Riordan DS, O'Brien T, Grant CS, Gharib H, Weaver A, Gharib H, van Heerden JA (1993) 'Surgical management of hyperparathyroidism in multiple endocrine neoplasia syndrome'. Surgery, 114 :1031-1039 [Details]
(1993) 'Lipoprotein compositional changes in the fasting and postprandial state on a high-carbohydrate low-fat and a high-fat diet in subjects with noninsulin-dependent diabetes mellitus'
O'Brien T, Nguyen TT, Buithieu J, Kottke BA (1993) 'Lipoprotein compositional changes in the fasting and postprandial state on a high-carbohydrate low-fat and a high-fat diet in subjects with noninsulin-dependent diabetes mellitus'. J Clin Endocrinol Metab, 77 :1345-1351 [Details]
(1993) 'Insulin surrogates in insulinoma'
O'Brien T, O'Brien PC, Service FJ (1993) 'Insulin surrogates in insulinoma'. J Clin Endocrinol Metab, 77 :448-451 [Details]
(1993) 'Hyperlipidemia in patients with primary and secondary hypothyroidism'
O'Brien T, Dinneen SF, O'Brien PC, Palumbo PJ (1993) 'Hyperlipidemia in patients with primary and secondary hypothyroidism'. Mayo Clinic Proceedings, 68 :860-866 [Details]
(1993) 'Hypertension and dyslipidemia in patients with insulinoma'
O'Brien T, Young WF Jr, Palumbo PJ, O'Brien PC, Service FJ (1993) 'Hypertension and dyslipidemia in patients with insulinoma'. Mayo Clinic Proceedings, 68 :141-146 [Details]
(1992) 'Acute physical exercise alters apolipoprotein E and CIII concentrations of apo E rich very low density lipoprotein fraction'
Klein L, Miller TD, Radam TE, O'Brien T, Nguyen TT, Kottke BA (1992) 'Acute physical exercise alters apolipoprotein E and CIII concentrations of apo E rich very low density lipoprotein fraction'. Atherosclerosis, 97 :37-51 [Details]
(1991) 'A case of pregnancy associated osteoporosis and empty sella syndrome'
Kinsella P, O'Brien T, Brosnan E, O'Sullivan DJ. (1991) 'A case of pregnancy associated osteoporosis and empty sella syndrome'. IRISH MEDICAL JOURNAL, 84 :25-26 [Details]
(1990) 'Autonomic Dysfunction and Silent Myocardial Ischemia on Exercise Testing in Diabetes Mellitus'
Murray DM, O'Brien T, Mulrooney R, O'Sullivan DJ (1990) 'Autonomic Dysfunction and Silent Myocardial Ischemia on Exercise Testing in Diabetes Mellitus'. Diabetic Medicine, 7 :580-584 [Details]
(1990) 'Fabry's Disease: A Family Study'
O'Brien T, Bolster M, Sullivan P. (1990) 'Fabry's Disease: A Family Study'. IRISH JOURNAL OF MEDICAL SCIENCE, 159 :580-584 [Details]
(1990) 'Usefulness of Biochemical Screening of Diabetic Patients for Hemochromatosis'
O'Brien T, Barrett B, Murray DM, Dinneen S, O'Sullivan DJ (1990) 'Usefulness of Biochemical Screening of Diabetic Patients for Hemochromatosis'. Diabetes Care, 13 (5):532-534 [Details]

Book Chapters

  Year Publication
(2015) 'Chapter 5: Isolation of Endothelial Progenitor Cells (EPCs)'
Liew A, O'Brien T (2015) 'Chapter 5: Isolation of Endothelial Progenitor Cells (EPCs)' In: Handbook of Vascular Biology Techniques. Springer: Springer. [DOI] [Details]
(2013) 'Stem cell microencapsulation for therapeutic angiogenesis'
Sanz-Nogués C., Thomas D., Pandit A., O'Brien T. (2013) 'Stem cell microencapsulation for therapeutic angiogenesis' In: Biomaterials for stem cell therapy: State of the art and vision for the future. U.S.A: Science Publishers. [Details]
(2012) 'Isolation of Circulating Angiogenic Cells'
Vaughan E, O’Brien T. (2012) 'Isolation of Circulating Angiogenic Cells' In: Progenitor Cells: Methods and Protocols, Methods Mol Biol. U.S.A: Springer. [Details]
(2012) 'Mesenchymal stem cells in regenerative medicine'
Murphy, M., Curtin, C., Duffy, G., Kavanagh, C., O'Brien, T., Barry, F. (2012) 'Mesenchymal stem cells in regenerative medicine' In: Regenerative Medicine and Cell Therapy. Amsterdam, The Netherlands: IOS Press. [DOI] [Details]
(2012) 'Mesenchymal Stem Cells: Clinical Applications (An Overview)'
Liew A, O’Brien T. (2012) 'Mesenchymal Stem Cells: Clinical Applications (An Overview)' In: Stem Cells and Cancer Stem Cells, Volume 6. U.S.A: Springer. [Details]
(2011) 'Topical stem and progenitor cell therapy for Diabetic foot ulcers'
O'Loughlin A, O'Brien T, (2011) 'Topical stem and progenitor cell therapy for Diabetic foot ulcers' In: Type 1 Diabetes/Book 3. Croatia: In Tech Publishers. [Details]
(2011) 'Cytokine-Induced B-cell stress and death in Type 1 Diabetes'
Vincenz L, Szegezdi E, Jaegar R, Holohan C, O'Brien T, Samali A. (2011) 'Cytokine-Induced B-cell stress and death in Type 1 Diabetes' In: Type 1 Diabetes Complications. Croatia: Intech Publisher. [Details]
(2011) 'ß Cell Protection by Inhibition of iNOS through Lentiviral Vector-Based Strategies'
Hynes SO, McCabe C, O'Brien T (2011) 'ß Cell Protection by Inhibition of iNOS through Lentiviral Vector-Based Strategies' In: Methods Mol Biol. [Details]
(2010) 'Controversies in the management of diabetes mellitus'
O'Reilly M, O Brien T (2010) 'Controversies in the management of diabetes mellitus' In: Are statins the best way to treat diabetic dyslipidemia. [Details]
(2010) 'Disorders of HDL metabolism'
Smith D, Dubé M, Jellinger P, Mehta A, Montague T, Murphy B, O’Brien T, Patel A, Rodbard H. (2010) 'Disorders of HDL metabolism' In: Serum Lipid disorders. USA: American College of Endocrinology CME Publication. [Details]
(2010) 'HPLC Purification of Adenoviral Vectors'
Eglon M, McGrath B, O'Brien, T (2010) 'HPLC Purification of Adenoviral Vectors' In: Methods Mol Biol. [Details]
(2010) 'Generation of antioxidant adenovirus gene transfer vectors encoding CuZnSOD, MnSOD, and catalase'
Duffy AM, O'Brien T, McMahon JM (2010) 'Generation of antioxidant adenovirus gene transfer vectors encoding CuZnSOD, MnSOD, and catalase' In: Advanced Protocols in Oxidative Stress II. Methods in Molecular Biology Volume 594. New York: Springer. [Details]
(2008) 'Therapy of Dyslipidemias'
Murphy, MS, O'Brien, T (2008) 'Therapy of Dyslipidemias' In: Pharmacology and Therapeutics. [Details]
(2006) 'Disorders of high-density lipoprotein cholesterol'
O'Brien, T (2006) 'Disorders of high-density lipoprotein cholesterol' In: The American Association of Clinical Endocronologists. [Details]
(2004) 'Gene transfer in Endothelial Dysfunction and Hypertension'
Sen S, Strappe, PM, O'Brien T (2004) 'Gene transfer in Endothelial Dysfunction and Hypertension' In: Humana Press Inc Totowa, NJ. [Details]
(2004) 'Analysis of Superoxide Anion Production in Tissue'
Michela Zanetti, Livius V d'Uscio, Timothy E Peterson, Zvonimir S Katusic and Timothy O'Brien (2004) 'Analysis of Superoxide Anion Production in Tissue' In: Edited by JP Fennell and AH Baker. [Details]
(2003) 'Endocrine and metabolic problems'
Bell, M, Flaherty, G, O'Brien, T, Mulkerrin, EC (2003) 'Endocrine and metabolic problems' In: Medicine for Older Patients – Cases and Practice. Dublin: Eireann Publications. [Details]
(2000) 'Cerebrovascular effects of recombinant endothelial nitric oxide synthase gene expression and activation'
Katusic ZS, Chen AFY, O'Brien T (2000) 'Cerebrovascular effects of recombinant endothelial nitric oxide synthase gene expression and activation' In: Mechanisms of Cerebrovascular Function and Regulation. [Details]
(2000) 'Functional influence of gene transfer of recombinant nitric oxide synthase to cardiovascular system'
Chen AFY, O'Brien T, Katusic ZS (2000) 'Functional influence of gene transfer of recombinant nitric oxide synthase to cardiovascular system' In: NITRIC OXIDE Biology and Pathobiology, Section III, Principles of Pathobiology. [Details]
(1999) 'Therapeutic implications of recombinant endothelial nitric oxide synthase gene expression in cerebral and peripheral arteries'
Chen AFY, O'Brien T, Katusic ZS (1999) 'Therapeutic implications of recombinant endothelial nitric oxide synthase gene expression in cerebral and peripheral arteries' In: Pathophysiology and Clinical Applications of Nitric Oxide, Therapeutic Applications 5. [Details]
(1999) 'Adenoviral vectors for cardiovascular gene transfer'
Caplice N, O'Brien T, Simari RD (1999) 'Adenoviral vectors for cardiovascular gene transfer' In: Adenoviral Vectors for Cardiovascular Diseases. [Details]
(1998) 'Adventitial fibroblasts as target cells for expression of recombinant endothelial nitric oxide synthase gene'
Katusic ZS, Tsutsui M, Chen AFY, O'Brien T, Crotty TB. S.Moncada, N.Toda, H Maeda, E.A. Higgs. (1998) 'Adventitial fibroblasts as target cells for expression of recombinant endothelial nitric oxide synthase gene' In: The Biology of Nitric Oxide. London: Portland Press. [Details]

Conference Publications

  Year Publication
(2016) Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland
Gaspar, D., Griffin, M., O’Brien, T., Pandit, A., Zeugolis, D. (2016) A Multifactorial Approach towards Mesenchymal Stem Cell Phenotype Maintenance and Enhanced Matrix Deposition In Vitro Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland [Details]
(2016) 10th World Biomaterials Congress
Thomas, D., Marsico, G., Thirumaran, A., Lukasz, B., Thompson, K., Dockery, P., Rodriguez, B., Marchetti-Deschmann, M., O'Brien, T. and Pandit, A. (2016) A Shape-controlled Tunable Microgel Cell Delivery Platform for Low-dose Delivery of Primed Stem Cells for In Vivo Therapeutic Neovascularization 10th World Biomaterials Congress [Details]
(2016) A Shape-controlled Tunable Microgel Cell Delivery Platform for Low-dose Delivery of Primed Stem Cells for In Vivo Therapeutic Neovascularization
Thomas, D., Marsico, G., Thirumaran, A., Chen, X., Lukasz, B., Thompson, K., Quondamatteo, F., Dockery, P., Rodriguez, B., Marchetti-Deschmann, M., O’Brien, T. and Pandit, A. (2016) Tissue Engineering and Regenerative Medicine International Society (TERMIS) – EU Meeting A Shape-controlled Tunable Microgel Cell Delivery Platform for Low-dose Delivery of Primed Stem Cells for In Vivo Therapeutic Neovascularization [Details]
(2016) Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland
Thomas, D., Marsico, G., Thirumaran, A., Lukasz, B., Thompson, K., Dockery, P., Quondamatteo, F., Rodriguez, B., MarchettiDeschmann, M., O’Brien, T. and Pandit, A. (2016) A Shape-controlled Tunable Microgel Cell Delivery Platform for Low-Dose Delivery of Primed Stem Cells for In Vivo Therapeutic Neovascularization Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland [Details]
(2017) International Society for Stem Cell Research
6. Avazzadeh S, McDonagh K ,Quinlan L. Dockery P, Li M, McInerney V, Krawczyk J , O’Brien T, Gallagher L, Shen S (2017) Role of NRXN1 in neurodevelopmental disease: From stem cell to clinical phenotypes International Society for Stem Cell Research [Details]
(2016) Pilot study of biomarkers in Diabetic Kidney Disease
Griffin, TP,Islam, MN,Martin, WP,Cormican, S,Naicker, SD,Logue, S,O'Shea, PM,O'Brien, T,Griffin, MD (2016) IRISH JOURNAL OF MEDICAL SCIENCE Pilot study of biomarkers in Diabetic Kidney Disease , pp.404-404 [Details]
(2016) Influence of chronic kidney disease aetiology on outcomes of multi-disciplinary diabetic renal clinic attendance
Martin, WP,Griffin, TP,Lappin, D,Griffin, D,O' Brien, T,Griffin, MD (2016) IRISH JOURNAL OF MEDICAL SCIENCE Influence of chronic kidney disease aetiology on outcomes of multi-disciplinary diabetic renal clinic attendance , pp.375-376 [Details]
(2013) Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin
Niall Bergin, Nicolas Madigan, Bridget Breen, Peter Owens, Timothy O’Brien, Anthony Windebank, Siobhan McMahon (2013) Expression of CD68 positive macrophages in mesenchymal stem cell and schwann cell loaded scaffolds in a transection model of spinal cord injury Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin [Details]
(2008) Gordon Research Conference, Musculoskeletal Biology & Bioengineering
LA Mylotte, E Szegezdi, T O'Brien, M Murphy, C Coleman, F Barry (2008) Investigation of chondrogenic differentiation of MSCs in a hypoxic environment. Gordon Research Conference, Musculoskeletal Biology & Bioengineering, Proctor Academy, Andovery, NH Gordon Research Conference, Musculoskeletal Biology & Bioengineering [Details]
(2008) Annual Meeting of the International Society for Cellular Therapy
LA Mylotte, E Szegezdi, T O'Brien, M Murphy, C Coleman, F Barry (2008) Investigation of chondrogenic differentiation of MSCs in a hypoxic environment Annual Meeting of the International Society for Cellular Therapy , 17-MAY-08 - 20-MAY-08 [Details]
(2013) Microscopy Society of Ireland, NUI Galway
Niall Bergin, Nicolas Madigan, Kerry Thompson, Timothy O’Brien, Anthony Windebank, Siobhan McMahon (2013) Analysis of proinflammatory and anti-inflammatory macrophages within cell loaded scaffolds in a transection model of spinal cord injury Microscopy Society of Ireland, NUI Galway [Details]
(2013) Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin
Siobhan McMahon, Nicolas Madigan, Niall Bergin, Bridget Breen, Peter Owens, Timothy O’Brien, Anthony Windebank (2013) Analysis of axonal regeneration and inflammation within schwann cell and mesenchymal stem cell loaded polymer scaffolds in the transected rat spinal cord Anatomical Society of Great Britain and Ireland meeting: Form and Function in Regenerative Medicine, RCSI, Dublin [Details]
(2012) International Conference for Healthcare and Medical Students 2011
Scott, J,Liew, A,Shaw, G,Murphy, M,Barry, F,O'Brien, T (2012) Angiogenic potential of clonal populations of human mesenchymal stem cells International Conference for Healthcare and Medical Students 2011 [Details]
(2012) 12th Combined Meeting of the Orthopaedic Associations
Murphy, M,O'Brien, T (2012) THE MESENCHYMAL STEM CELL (MSC) SECRETED FACTORS MCP-1, CCL5, TGF-β1 AND VEGF ASSIST IN CANCER CELL PROLIFERATION, INVASION AND IN THE FORMATION OF BONE METASTASES THROUGH THE PROMOTION OF EPITHELIAL TO MESENCHYMAL TRANSITION (EMT) 12th Combined Meeting of the Orthopaedic Associations , pp.160-160 [Details]
(2011) Adenoviral Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses after Cell Transplantation
Treacy, O,Heinzl, T,Cregg, M,Wilk, M,Odoardi, F,O'Brien, T,Ryan, A,Nosov, M,Ritter, T (2011) Adenoviral Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses after Cell Transplantation , pp.72-72 [Details]
(2011) American College of Cardiology
Flynn, A; Chen, XZ; O'Connell, E; Barry, F; O'Brien, T. (2011) The Pre-Conditioning of Unrestricted Somatic Stem Cells Alters Their Genotype, but Does Not Enhance Their Ability to Repair Cardiac Damage American College of Cardiology , pp.209-209 [Details]
(2011) Heart 97(20):e7
Leszczynska, A,O'Doherty, A,Barry, F,O'Brien, T,Murphy, M (2011) 8 Ossification of atherosclerotic plaque: the role of vessel derived stem cells Heart 97(20):e7 [Details]
(2010) Irish Cardiac Society AGM
Flynn, A,Chen, X,O'Connell, E,Duffy, A,Shaw, G,O'Loughlin, A,Dennedy, C,McHale, C,MacNeill, B,Nash, P,Crowley, J,Daly, K,Barry, F,O'Brien, T (2010) Unrestricted Somatic Stem Cells Improve Cardiac Function Post-Myocardial Infarction With and Without Pre-Conditioning. Authors Irish Cardiac Society AGM , pp.401-402 [Details]
(2010) Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU)
McCullagh K; Hughes O; Cooney R; O'Connell E; Mashayekhi K; Eglon M; O' Brien T. (2010) Gene Profile Analysis of NOS Transduced Human Arterial Smooth Muscle Cells Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU) [Details]
(2009) ESGCT meeting, Hannover, Germany
Eleanor Donnelly, Peter Dockery, John Fraher, Padraig Strappe, Daniel O’Toole, Nicolas Madigan, Lisa McGinley, Anthony Windebank, Timothy O’Brien, Siobhan McMahon. (2009) Lentiviral vector treatment of the inhibitory spinal cord injury environment in vitro and in vivo ESGCT meeting, Hannover, Germany [Details]
(2009) 6th Australasian Gene Therapy Society Meeting, Sydney
Siobhan McMahon, Gemma Rooney, Eleanor Donnelly, Timothy O’Brien, John Fraher, Anthony Windebank, Peter Dockery, David Hampton, Padraig Strappe. (2009) An astrocyte-dorsal root ganglion co-culture model to assess neurite outgrowth from lentiviral vector expressed Neurotrophin-3 6th Australasian Gene Therapy Society Meeting, Sydney [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
Eleanor Donnelly, Lisa McGinley, Peter Dockery, John Fraher, Padraig Strappe, Daniel O’Toole, Nicolas Madigan, Gemma Rooney, Timothy O’Brien, Siobhan McMahon. (2008) Silencing Ng2 Inhibitory Factor And Its Effect On Dorsal Root Ganglia Neurite Outgrowth Neuroscience Ireland Meeting, NUI Galway [Details]
(2008) Circulation, Americal Heart Association
Mooney, E. J.,Mackle, J. N.,Barry, F.,O'Brien, T.,Murphy, M.,Barron, V. (2008) Electrical Stimulation of Mesenchymal Stem Cells in the Presence of Carbon Nanotubes Circulation, Americal Heart Association [Details]
(2008) OARSI
Curtin C,Murphy, M,Curtin W, Dockery P, O'Flatharta C,O'Brien,T, Barry F (2008) DEVELOPMENT OF MESENCHYMAL STEM CELL TARGETING STRATEGIES FOR CARTILAGE REPAIR OARSI [Details]
(2008) Neuroscience Ireland Meeting, NUI Galway
Siobhan S. McMahon, Silke Albermann, Gemma E. Rooney, Timothy O’Brien, Yolanda Garcia, Peter Dockery, Anthony J. Windebank, Timothy E. Allsopp, Frank P. Barry. (2008) Analysis of neural stem cells following transplantation into injured rat spinal cord Neuroscience Ireland Meeting, NUI Galway [Details]
(2008) ESGCT meeting, Brugge, Belgium
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O’Toole, Lisa McGinley, Timothy O’Brien (2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord ESGCT meeting, Brugge, Belgium [Details]

Other Journals

  Year Publication
(2017) '• Feasibility of autologous mesenchymal stem cells therapy for patients with no-option critical limb ischemia'
Mohamed, S. ; Howard, L. ; Duffy, A. ; Finnerty, A. ; Holohan, M. ; Doroshenkova, T. ; Mcinerney, V. ; Hayat, A. ; Krawczyk, J. ; Naughton, S. ; Tarpey, M. ; Moloney, T. ; Kavanagh, E. ; Liew, A. ; Tubassam, M. ; Walsh, S. ; O'Brien, T. (2017) '• Feasibility of autologous mesenchymal stem cells therapy for patients with no-option critical limb ischemia' Cytotherapy, The Journal of Cell Therapy, 19 (5) :S186-S187. [DOI] [Details]
(2017) 'Autologous mesenchymal stem cells as a novel therapy for no-option critical limb ischemia: Preliminary results of a phase 1 study'
Mohamed, S. ; Mcinerney, V. ; Dunne, A. ; Hayat, A. ; Krawczyk, J. ; Naughton, S. ; Tarpey, M. ; Finnerty, A. ; Holohan, M. ; Duffy, A. ; Moloney, T. ; Kavanagh, E. ; Burke, P. ; Abdeldaim, Y. ; Moloney, M. Clarke ; Howard, L. ; Liew, A. ; Tubassam, M. ; Walsh, S. ; O'Brien, T. (2017) 'Autologous mesenchymal stem cells as a novel therapy for no-option critical limb ischemia: Preliminary results of a phase 1 study' Cytotherapy, 19 (5) :S198-S198. [DOI] [Details]
(2005) 'Mesenchymal Stem Cell Transplantation for Tissue Repair'
Barry FP, Murphy JM, O’Brien T, Mahon BP (2005) 'Mesenchymal Stem Cell Transplantation for Tissue Repair' Seminars in Plastic Surgery, 19 (3) :229-239. [Details]

Conference Contributions

  Year Publication
Autologous mesenchymal stem cells as a novel therapy for no-option critical limb ischemia: preliminary results of a phase 1 study,
Mohamed, S,McInerney, V,Dunne, A,Hayat, A,Krawczyk, J,Naughton, S,Tarpey, M,Finnerty, A,Duffy, A,Moloney, T,Kavanagh, E,Howard, L,Liew, A,Tubassam, M,Walsh, SR,O'Brien, T IRISH JOURNAL OF MEDICAL SCIENCE. [Published Abstract], Autologous mesenchymal stem cells as a novel therapy for no-option critical limb ischemia: preliminary results of a phase 1 study, Sylvester O'Halloran Surgical Symposium Limerick . [Details]
(2017) 25th Sylvester O’Halloran Perioperative Scientific Symposium, 2017,
Mohamed, S; McInerney, V; Dunne, A.; Hayat, A; Krawczyk, J; Naughton, S; Tarpey, M; Finnerty, A; Duffy, A; Moloney, T; Kavanagh, E; Howard, L; Liew, A; Tubassam, M; Walsh S; O’Brien, T. (2017) Autologous mesenchymal stem cells as a novel therapy for no-option critical limb ischemia: preliminary results of a phase 1 study. [Oral Presentation], 25th Sylvester O’Halloran Perioperative Scientific Symposium, 2017, University of Limerick , 02-MAR-17 - 04-MAR-17. [Details]
(2016) Metformin monotherapy versus dual therapy with metformin and a dipeptidyl peptidase-IV inhibitor for treatment of type 2 diabetes mellitus: a systematic review and meta-analysis,
Tobin-Schnittger, P,Ong, G,O'Brien, T,Liew, A (2016) IRISH JOURNAL OF MEDICAL SCIENCE. [Conference Organising Committee Chairperson], Metformin monotherapy versus dual therapy with metformin and a dipeptidyl peptidase-IV inhibitor for treatment of type 2 diabetes mellitus: a systematic review and meta-analysis, IRISH ENDOCRINE SOCIETY MEETING , 14-OCT-16. [Details]
(2011) OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS,
Leszczynska, A,O'Doherty, A,Barry, F,O'Brien, T,Murphy, M (2011) HEART. OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS, dfg , 14-FEB-12 - 16-FEB-12. [Details]

Abstract

  Year Publication
(2016) The Cardioprotective Effect of MSC Secreted Protein in an In Vitro Model of Myocardial Infarction.
Siti-Ismail, N,Farrell, E,Harte, M,Creane, M,Murphy, M,O'Brien, T,Barry, F (2016) The Cardioprotective Effect of MSC Secreted Protein in an In Vitro Model of Myocardial Infarction. Abstract [Details]
(2015) A Shape-controlled Microgel Cell Delivery Platform for Delivery of Primed Stem Cells for In Vivo Therapeutic Neovascularization.
Thomas, D,Marsico, G,Thirumaran, A,Chen, X,O'Brien, T,Pandit, A (2015) A Shape-controlled Microgel Cell Delivery Platform for Delivery of Primed Stem Cells for In Vivo Therapeutic Neovascularization. Abstract [Details]
(2015) COMPARISON OF BONE MARROW STROMAL CELL (BMSC) PRODUCTION METHODS AND PRODUCTS FROM MULTIPLE CENTERS.
Stroncek, D,Jin, P,Reems, JA,Cancelas, J,Nayak, R,Shaw, G,O'Brien, T,McKenna, D,Armant, M,Silberstein, L,Gee, A,Hei, D,Hematti, P,Civini, S,Sabatino, M,Robey, P (2015) COMPARISON OF BONE MARROW STROMAL CELL (BMSC) PRODUCTION METHODS AND PRODUCTS FROM MULTIPLE CENTERS. Abstract [Details]
(2015) A Multifactorial Approach Towards Enhanced Extracellular Matrix Deposition and Maintenance of Mesenchymal Stem Cell Phenotype using Macromolecular Crowding and Low Oxygen Tension.
Gaspar, D,Cigognini, D,Kumar, P,Satyam, A,Alagesan, S,Sanz-Noguez, C,Griffin, M,O'Brien, T,Pandit, A,Zeugolis, D (2015) A Multifactorial Approach Towards Enhanced Extracellular Matrix Deposition and Maintenance of Mesenchymal Stem Cell Phenotype using Macromolecular Crowding and Low Oxygen Tension. Abstract [Details]
(2015) Tacrolimus Co-administration Suppresses Anti-donor Immune Response to Allogeneic Mesenchymal Stem Cells but does not Influence Disease Severity in a Mouse Model of Hind Limb Ischemia.
Sanz-Nogues, C,Alagesan, S,Creane, M,Conroy, C,Chen, X,Dockery, P,Griffin, M,O'Brien, T (2015) Tacrolimus Co-administration Suppresses Anti-donor Immune Response to Allogeneic Mesenchymal Stem Cells but does not Influence Disease Severity in a Mouse Model of Hind Limb Ischemia. Abstract [Details]
(2015) Genetic Modification of Mesenchymal Stem Cells for Targeted Systemic Cell Therapy in Critical Limb Ischemia.
Thirumaran, A,O'Brien, T,Howard, L (2015) Genetic Modification of Mesenchymal Stem Cells for Targeted Systemic Cell Therapy in Critical Limb Ischemia. Abstract [Details]
(2015) Co-transfection of Decorin and Interleukin-10 Genes Additively Silences TGF-beta 1 Related Pro-fibrotic ECM Gene Expression in Human Tenocytes.
Akogwu, A,Thomas, D,Browne, S,Gaspar, D,O'Brien, T,Pandit, A,Zeugolis, D (2015) Co-transfection of Decorin and Interleukin-10 Genes Additively Silences TGF-beta 1 Related Pro-fibrotic ECM Gene Expression in Human Tenocytes. Abstract [Details]
(2015) Enhancement of Wound Healing with Increased Angiogenesis in a Diabetic Rabbit Ulcer Model by Topical Application of CD362+Human Mesenchymal Stem Cells (Cyndacel-M) Seeded in Excellagen (TM) Scaffold.
Patil, SB,Chen, X,Watson, L,Loftus, P,Flynn, LO,Chandler, LA,Rubanyi, GM,Elliman, SJ,O'Brien, T (2015) Enhancement of Wound Healing with Increased Angiogenesis in a Diabetic Rabbit Ulcer Model by Topical Application of CD362+Human Mesenchymal Stem Cells (Cyndacel-M) Seeded in Excellagen (TM) Scaffold. Abstract [Details]
(2015) Non-diabetic MSCs Support Diabetic Femoral Fracture Healing.
Watson, L,Chen, X,Loftus, PG,McDonnell, P,O'Brien, T,Coleman, C (2015) Non-diabetic MSCs Support Diabetic Femoral Fracture Healing. Abstract [Details]
(2015) THERAPEUTIC POTENTIAL OF MSCs IN CRITICAL LIMB ISCHEMIA.
O'Brien, T (2015) THERAPEUTIC POTENTIAL OF MSCs IN CRITICAL LIMB ISCHEMIA. Abstract [Details]
(2015) A Regulatory Body-Approved Methodology for Localizing and Quantifying Human Mesenchymal Stem Cells Administered to Murine Pre-Clinical Models.
Creane, M,Howard, L,O'Brien, T,Coleman, C (2015) A Regulatory Body-Approved Methodology for Localizing and Quantifying Human Mesenchymal Stem Cells Administered to Murine Pre-Clinical Models. Abstract [Details]
(2014) Calcium Conundrum.
Linane, H,Egan, A,Griffin, T,Quill, D,O'Brien, T (2014) Calcium Conundrum. Abstract [Details]
(2014) Enhanced extracellular matrix deposition and maintenance of mesenchymal stem cell phenotype in vitro using macromolecular crowding and low oxygen tension.
Cigognini, D,Kumar, P,Satyam, A,Sanz-nogues, C,O'brien, T,Pandit, A,Zeugolis, D (2014) Enhanced extracellular matrix deposition and maintenance of mesenchymal stem cell phenotype in vitro using macromolecular crowding and low oxygen tension. Abstract [Details]
(2014) Clinical profile of patients with Type 1 diabetes attending an Irish teaching hospital.
Cotter, TG,O'Brien, T,Dinneen, SF,Dunne, F,Bell, M,Finucane, FM,Gately, M (2014) Clinical profile of patients with Type 1 diabetes attending an Irish teaching hospital. Abstract [Details]
(2014) Multisystem Erdheim-Chester Disease: A Case Report.
Brennan, AM,O'Brien, T (2014) Multisystem Erdheim-Chester Disease: A Case Report. Abstract [Details]
(2014) Influence of adiposity on insulin requirements and glycaemic control in children and adolescents with type 1 diabetes.
Cotter, T,Jennings, P,Burke, H,Dinneen, SF,Bell, M,Dunne, F,Geoghegan, R,Moylett, E,O'Brien, T,Finucane, FM (2014) Influence of adiposity on insulin requirements and glycaemic control in children and adolescents with type 1 diabetes. Abstract [Details]
(2014) Topical application of CD362+human mesenchymal stem cells (cyndacel-M) seeded in Excellagen (TM) scaffold augments wound healing in a diabetic wound model.
Patil, SB,Chen, X,Watson, L,Loftus, P,O'Flynn, L,Chandler, LA,Rubanyi, GM,Elliman, SJ,O'Brien, T (2014) Topical application of CD362+human mesenchymal stem cells (cyndacel-M) seeded in Excellagen (TM) scaffold augments wound healing in a diabetic wound model. Abstract [Details]
(2014) ENCAPSULATION OF HUMAN MESENCHYMAL STEM CELLS IN SODIUM CELLULOSE SULFATE-BASED MICROCAPSULES REQUIRES IMMORTALIZATION.
Sanz-Nogues, C,Horan, J,Ryan, G,Kassem, M,O'Brien, T (2014) ENCAPSULATION OF HUMAN MESENCHYMAL STEM CELLS IN SODIUM CELLULOSE SULFATE-BASED MICROCAPSULES REQUIRES IMMORTALIZATION. Abstract [Details]
(2014) An Audit on Insulin Pump Therapy Use at an Irish Teaching Hospital.
Cotter, TG,Dinneen, SF,Bell, M,Dunne, F,Finucane, FM,O'Brien, T (2014) An Audit on Insulin Pump Therapy Use at an Irish Teaching Hospital. Abstract [Details]
(2014) A comparison of endochondral ossification by vessel-derived and mesenchymal stem cells in wild type and ApoE knockout mice: interleukin 6 as a potential mediator of plaque-associated calcification.
Leszczynska, A,O'Doherty, A,Farrell, E,O'brien, F,O'brien, T,Murphy, M (2014) A comparison of endochondral ossification by vessel-derived and mesenchymal stem cells in wild type and ApoE knockout mice: interleukin 6 as a potential mediator of plaque-associated calcification. Abstract [Details]
(2014) A 3 MONTH TOXICOLOGY STUDY OF BONE MARROW DERIVED MESENCHYMAL STROMAL CELLS MANUFACTURED UNDER GMY AND ADMINISTERED ONCE BY INTRAMUSCULAR INJECTION.
Creane, M,Elroy, MM,Dawood, CS,Duffy, A,O'Brien, T (2014) A 3 MONTH TOXICOLOGY STUDY OF BONE MARROW DERIVED MESENCHYMAL STROMAL CELLS MANUFACTURED UNDER GMY AND ADMINISTERED ONCE BY INTRAMUSCULAR INJECTION. Abstract [Details]
(2013) The Spectrum of Disorders Manifesting as Hypercalcaemia in Pregnancy.
Kyithar, P,Yasmin, T,Quill, D,Kerin, M,Dunne, F,O'Brien, T,Gaffney, G,Bell, M,Finucane, FM (2013) The Spectrum of Disorders Manifesting as Hypercalcaemia in Pregnancy. Abstract [Details]
(2013) Apoptosis in cell-loaded scaffolds in a transection model of rat spinal cord injury.
Keane, E,Madigan, NN,Canney, M,Thompson, K,O'Brien, T,Windebank, AJ,McMahon, SS (2013) Apoptosis in cell-loaded scaffolds in a transection model of rat spinal cord injury. Abstract [Details]
(2013) Prothrombotic Activity and Reduction in Coronary Flow Reserve Associated With Therapeutic Intracoronary Delivery of Bone Marrow-Derived Mesenchymal Stem Cells is Ameliorated by Heparin Co-Administration in a Porcine Myocardial Infarction Model.
Gleeson, BM,Martin, K,Kumar, AH,Ali, MT,Barry, FP,O'Brien, T,Caplice, NM (2013) Prothrombotic Activity and Reduction in Coronary Flow Reserve Associated With Therapeutic Intracoronary Delivery of Bone Marrow-Derived Mesenchymal Stem Cells is Ameliorated by Heparin Co-Administration in a Porcine Myocardial Infarction Model. Abstract [Details]
(2013) Establishing in Vitro Models of Autism Spectrum Disorders Using Induced Pluripotent Stem Cells. ISSCR Conference 2013, Boston.
McDonagh K, Sotthibundhu A, Thompson K, McDermott E, Dockery P., Schwartz PH, Brick DJ, O’Brien T, Barry F, Shen S* (2013) Establishing in Vitro Models of Autism Spectrum Disorders Using Induced Pluripotent Stem Cells. ISSCR Conference 2013, Boston. Abstract [Details]
(2013) Autophagy mechanism in reprogramming and induced pluripotent stem cells. ISSCR Conference 2013, Boston.
Sotthibundhu A, McDonagh K, Klawiter A, Thompson K, Dockery P., Devine M, Kunath T, O’Brien T, Barry F, Shen S* (2013) Autophagy mechanism in reprogramming and induced pluripotent stem cells. ISSCR Conference 2013, Boston. Abstract [Details]
(2013) Therapeutic Potential of Different Osteopontin Isoforms in Pulmonary and Vascular Diseases.
O'Toole, D,Liew, A,Gaffney, D,Pandit, A,O'Brien, T (2013) Therapeutic Potential of Different Osteopontin Isoforms in Pulmonary and Vascular Diseases. Abstract [Details]
(2013) Clinical Profile of Patients with Type 1 Diabetes at Galway University Hospital.
Cotter, TG,Dinneen, S,Bell, M,Dunne, F,Finucane, F,Gately, M,O'Brien, T (2013) Clinical Profile of Patients with Type 1 Diabetes at Galway University Hospital. Abstract [Details]
(2012) Use of 1-84PTH Pump for the Treatment of Hypoprathroidism.
Jafar-Mohammadi, B,Kinsella, S,Cunningham, A,Bell, M,O'Brien, T (2012) Use of 1-84PTH Pump for the Treatment of Hypoprathroidism. Abstract [Details]
(2012) An optimised microgel for maintaining 3D viable microenvironment for human mesenchymal stem cells.
Dilip, T,Fontana, G,Baustain, C,Thompson, K,Sugrue, T,Lalor, P,Dockery, P,O'Brien, T,Pandit, A (2012) An optimised microgel for maintaining 3D viable microenvironment for human mesenchymal stem cells. Abstract [Details]
(2012) Intramuscular allogeneic mesenchymal stem cells are of comparable efficacy to syngeneic MSCs in hind limb ischaemia of diabetic animals.
Liew, A,Baustian, C,Thomas, D,Vaughan, E,Chen, X,Nogues, CS,Creane, M,Alagesan, S,Owens, P,Horan, J,Ceredig, R,Dockery, P,Griffin, M,Duffy, A,O'Brien, T (2012) Intramuscular allogeneic mesenchymal stem cells are of comparable efficacy to syngeneic MSCs in hind limb ischaemia of diabetic animals. Abstract [Details]
(2012) Liposomal Surface Coatings of Metal Coronary Artery Stents for Efficient Non-Viral Gene Delivery to the Injured Vasculature.
Ganly, S,Hynes, SO,Sharif, F,Barron, V,McCullagh, K,McMahon, J,McHugh, P,Crowley, J,O'Brien, T,Greiser, U (2012) Liposomal Surface Coatings of Metal Coronary Artery Stents for Efficient Non-Viral Gene Delivery to the Injured Vasculature. Abstract [Details]
(2012) Osteopontin Treated Circulating Angiogenic Cells Enhance Functional Recovery in a SCID Model of Hindlimb Ischemia.
Vaughan, EE,Chen, XZ,Creane, M,Nogues, CS,Liew, A,Duffy, A,O'Brien, T (2012) Osteopontin Treated Circulating Angiogenic Cells Enhance Functional Recovery in a SCID Model of Hindlimb Ischemia. Abstract [Details]
(2012) OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS; HEART.
Leszczynska, A,O'Doherty, A,Barry, F,O'Brien, T,Murphy, M (2012) OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS; HEART. Abstract [Details]
(2012) Atherosclerotic environment accentuates endochondral ossification in vessel derived stem cells: In vitro and in vivo assessment.
Leszczynska, A,Farrell, E,O'Doherty, A,O'Brien, FJ,O'Brien, T,Barry, FP,Murphy, JM (2012) Atherosclerotic environment accentuates endochondral ossification in vessel derived stem cells: In vitro and in vivo assessment. Abstract [Details]
(2012) Short Term Safety of Human Bone Marrow Derived Mesenchymal Stem Cells in Immunodeficient Mice Following Intramuscular Delivery.
Creane, M,Alagesan, SK,Flavin, R,Hynes, S,Griffin, D,Thomas, D,Vaughan, E,Liew, A,Duffy, A,O'Brien, T (2012) Short Term Safety of Human Bone Marrow Derived Mesenchymal Stem Cells in Immunodeficient Mice Following Intramuscular Delivery. Abstract [Details]
(2012) Encapsulation of Mesenchymal Stemc Cells (MSCs) in sodium cellulose sulfate (SCS) and ply-diallyl-dimethyl-ammonium chloride (pDADMAC) microcapsules.
Sanz-Nogues, C,Horan, J,Ryan, G,O'Brien, T (2012) Encapsulation of Mesenchymal Stemc Cells (MSCs) in sodium cellulose sulfate (SCS) and ply-diallyl-dimethyl-ammonium chloride (pDADMAC) microcapsules. Abstract [Details]
(2012) Fibrin mediated proangiogenic and secretory control gene therapy for compromised wound healing.
Kulkarni, M,O'Loughlin, A,Vazquez-Martinez, R,Mashayekhi, K,Greiser, U,O'Toole, E,O'Brien, T,Malagon, M,Pandit, A (2012) Fibrin mediated proangiogenic and secretory control gene therapy for compromised wound healing. Abstract [Details]
(2012) Investigations into eNOS and Phosphomimetic eNOS Gene Delivery to the Vasculature.
Hynes, SO,Ganly, S,Sharif, F,Smith, L,McCullagh, K,Greiser, U,Katusic, Z,O'Brien, T (2012) Investigations into eNOS and Phosphomimetic eNOS Gene Delivery to the Vasculature. Abstract [Details]
(2011) Timing of mesenchymal stem cell transplantation into an area of acute myocardial infarction appears to be crucial for successful repair.
DaCosta, M,Flynn, A,Duffy, A,Nash, P,Barry, F,O'Brien, T (2011) Timing of mesenchymal stem cell transplantation into an area of acute myocardial infarction appears to be crucial for successful repair. Abstract [Details]
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida.
Dwyer RM, Ryan J, Havelin RJ, Morris JC, O'Flatharta C, Miller BW, Liu Z, Foley MJ, Barrett HH, Murphy M, Barry FP, O'Brien T and Kerin MJ (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida. Abstract [Details]
(2011) Topical Mesenchymal Stem Cells as Skin Replacement Therapy for Diabetic Foot Ulceration. Irish Association of Plastic Surgeons Summer Meeting 2011 Ashford Castle, Co Mayo.
Aonghus O'Loughlin, Mangesh Kulkarni, Peter Dockery, Georgina Shaw, Mary Murphy, Abhay Pandit, Timothy O'Brien (2011) Topical Mesenchymal Stem Cells as Skin Replacement Therapy for Diabetic Foot Ulceration. Irish Association of Plastic Surgeons Summer Meeting 2011 Ashford Castle, Co Mayo. Abstract [Details]
(2011) Mesenchymal stem cell therapy for diabetic foot ulceration.
O'Loughlin, A,Kulkarni, M,Dockery, P,Shaw, G,Mooney, E,Murphy, M,Pandit, A,O'Brien, T (2011) Mesenchymal stem cell therapy for diabetic foot ulceration. Abstract [Details]
(2010) Strategies for Promoting Survival of Transplanted Mesenchymal Stem Cells in a Myocardial Infarction Model. ASGCT 2010 13th Annual Meeting, Washington DC.
McGinley L, O'Toole D, Duffy A, Chen X, Stocca A, McMahon J, O'Brien T (2010) Strategies for Promoting Survival of Transplanted Mesenchymal Stem Cells in a Myocardial Infarction Model. ASGCT 2010 13th Annual Meeting, Washington DC. Abstract [Details]
(2010) Modification of the inhibitory enviroment of spinal cord injury by lentiviral vector containing NT-3 and shRNA for NG2. American Society of Gene and Cell Therapy, Washington DC.
Donnelly E, McMahon S, Dockery P, Fraher J, Strappe P, Madigan N, McGinley L, Windebank T, O'Brien T (2010) Modification of the inhibitory enviroment of spinal cord injury by lentiviral vector containing NT-3 and shRNA for NG2. American Society of Gene and Cell Therapy, Washington DC. Abstract [Details]
(2010) Strategies for Promoting Survival and Engraftment of Transplanted Mesenchymal Stem Cells. TERMIS EU2010, Galway.
McGinley, L, O'Toole D, Duffy A, Chen X, Stocca A, McMahon J, O'Brien T (2010) Strategies for Promoting Survival and Engraftment of Transplanted Mesenchymal Stem Cells. TERMIS EU2010, Galway. Abstract [Details]
(2010) Mediating Cell Delivery to a Diabetic Wound with the Use of a Collagen Scaffold. TERMIS-EU Meeting, Galway.
O'Loughlin A, Kulkarni M, Ward J, Dockery P, Pandit A, O'Brien T (2010) Mediating Cell Delivery to a Diabetic Wound with the Use of a Collagen Scaffold. TERMIS-EU Meeting, Galway. Abstract [Details]
(2010) Axonal Regeneration Supported by Schwann Cells and Mesenchymal Stem Cells through Hydrogel Scaffolds in the Transected Rat Spinal Cord.. TERMIS-EU Meeting, Galway.
Madigan NN, Rooney GE, Knight AM, Chen B, Gross LA, Dadsetan M, Yaszemski MJ, McMahon SS, O'Brien T, Windebank AJ (2010) Axonal Regeneration Supported by Schwann Cells and Mesenchymal Stem Cells through Hydrogel Scaffolds in the Transected Rat Spinal Cord.. TERMIS-EU Meeting, Galway. Abstract [Details]
(2010) ID 3558 Fibrin Microspheres Extend the Gene Delivery Capacity in a Fibrin Scaffold. ESB.
Kulkarni M, Greiser U, O'Brien T, Pandit A (2010) ID 3558 Fibrin Microspheres Extend the Gene Delivery Capacity in a Fibrin Scaffold. ESB. Tampere: Abstract [Details]
(2010) The role of osteopontin in endothelial progenitor cell function. European Association for the Study of Diabetes, 46th Annual Meeting, Stockholm.
Vaughan E, Duffy A, O'Brien T (2010) The role of osteopontin in endothelial progenitor cell function. European Association for the Study of Diabetes, 46th Annual Meeting, Stockholm. Abstract [Details]
(2010) Clinical Audit of Diabetes-related Lower Extremity Amputation in a Tertiary Referral Hospital. Irish Endocrine Society.
O'Loughlin A, McIntosh C, Dinneen SF, O'Brien T (2010) Clinical Audit of Diabetes-related Lower Extremity Amputation in a Tertiary Referral Hospital. Irish Endocrine Society. Abstract [Details]
(2010) Clinical Audit of Diabetes-related Lower Extremity Amputation in a Tertiary Referral Hospital. Irish Journal of Medical Science.
O'Loughlin A, McIntosh C, Dinneen SF, O'Brien T (2010) Clinical Audit of Diabetes-related Lower Extremity Amputation in a Tertiary Referral Hospital. Irish Journal of Medical Science. Abstract [Details]
(2010) Mesenchymal Stem Cells Overexpressing Bcl-xl Enhance Tissue Repair in an Osteoarthritic Cartilage Explant Model. 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, Louisiana, USA.
Curtin C, Murphy M, Ritter T, Curtin W, O'Brien T, Barry F (2010) Mesenchymal Stem Cells Overexpressing Bcl-xl Enhance Tissue Repair in an Osteoarthritic Cartilage Explant Model. 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, Louisiana, USA. Abstract [Details]
(2010) The role of MRP8 in in stent restenosis in the diabetic rat. TERMIS EU2010, Galway.
Stocca A, O'Toole D, Duffy A, O'Brien T (2010) The role of MRP8 in in stent restenosis in the diabetic rat. TERMIS EU2010, Galway. Abstract [Details]
(2010) Lentiviral vector treatment of the inhibitory spinal cord injury environment in vitro and in vivo. TERMIS-EU Meeting.
Donnelly E, Madigan N, Rooney G, Strappe P, Windebank A, O'Brien T, McMahon T (2010) Lentiviral vector treatment of the inhibitory spinal cord injury environment in vitro and in vivo. TERMIS-EU Meeting. Galway: Abstract [Details]
(2010) A comparision of three liposomal formulations for gene delivery from coronary artery stents. ASGCT 2010 Clinical Trials Training Course and 13th Annual Meeting Washington DC.
Ganly S, Hynes SO, Sharif F, McCullagh K, Barron V, Crowley J, McHugh P, O'Brien T, Greiser U (2010) A comparision of three liposomal formulations for gene delivery from coronary artery stents. ASGCT 2010 Clinical Trials Training Course and 13th Annual Meeting Washington DC. Abstract [Details]
(2010) Interleukin-10 Functionalised Scaffold Improves Stem Cell Retention In Vivo. TERMIS-NA, Orlando.
Carolyn Holladay, Karen Power, William Gallagher, Michael Sefton, Timothy O'Brien, Abhay Pandit (2010) Interleukin-10 Functionalised Scaffold Improves Stem Cell Retention In Vivo. TERMIS-NA, Orlando. Abstract [Details]
(2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Endocrine Society.
Vaughan EE, O'Loughlin A, Liew A, Duffy A, O'Brien T (2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Endocrine Society. Abstract [Details]
(2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Journal of Medical Science Poster 27.
Vaughan EE, O'Loughlin A, Liew A, Duffy A, O'Brien T (2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Journal of Medical Science Poster 27. Abstract [Details]
(2010) Preparing the wound to heal. Lower Extremity Wound Conference.
O'Loughlin A, McIntosh C, Dinneen SF, O'Brien T (2010) Preparing the wound to heal. Lower Extremity Wound Conference. Galway: Abstract [Details]
(2010) EPCs – Are they good for the Sole? Irish Endocrine Society. Irish Journal of Medical Science.
O'Louhglin A, Kulkarni M, Dockery P, Pandit A, O'Brien T (2010) EPCs – Are they good for the Sole? Irish Endocrine Society. Irish Journal of Medical Science. Abstract [Details]
(2010) Analysis of the glial scar of injured spinal cord following treatment with lentiviral vectors expressing NT-3 and shRNA for NG2. 7th FENS Forum of European Neuroscience.
McMahon S., Donnelly E., Kinnevane L , Strappe P. , Fraher J., Dockery P., Windebank A. & O'Brien T (2010) Analysis of the glial scar of injured spinal cord following treatment with lentiviral vectors expressing NT-3 and shRNA for NG2. 7th FENS Forum of European Neuroscience. Abstract [Details]
(2010) Management of diabetic ketoacidosis in the insulin analogue era.
Matiullah, S,Ryan, J,Tuohy, S,Cunnigham, A,Burke, H,Dunne, F,O'Brien, T,Bell, M,Dinneen, SF (2010) Management of diabetic ketoacidosis in the insulin analogue era. Abstract [Details]
(2010) American Diabetes Association recommendation adherence among patients attending the adult diabetes clinic in Galway University Hospital.
Cahill, S,Liew, A,O'Brien, T (2010) American Diabetes Association recommendation adherence among patients attending the adult diabetes clinic in Galway University Hospital. Abstract [Details]
(2010) Osteopontin Enhances the Angiogenic Potential of Endothelial Progenitor Cells. ASGCT 2010 13th Annual Meeting, Washington DC.
Vaughan E, Duffy A, O'Brien T (2010) Osteopontin Enhances the Angiogenic Potential of Endothelial Progenitor Cells. ASGCT 2010 13th Annual Meeting, Washington DC. Abstract [Details]
(2010) Cell therapy for diabetic ulceration: Collagen is an effective biomaterial for cell delivery to a diabetic wound. Communications for the Spring Meeting of the Medical Research Society, held in conjunction with the Academy of Medical Sciences and the Royal College of Physicians, London.
O'Loughlin A, Ward J, Kulkurani M, Pandit A, Dinneen S, O'Brien T (2010) Cell therapy for diabetic ulceration: Collagen is an effective biomaterial for cell delivery to a diabetic wound. Communications for the Spring Meeting of the Medical Research Society, held in conjunction with the Academy of Medical Sciences and the Royal College of Physicians, London. Abstract [Details]
(2010) The role of MRP8 in in stent restonosis in the diabetic rat. EASD.
Stocca A, O'Toole D, Duffy A, O'Brien T (2010) The role of MRP8 in in stent restonosis in the diabetic rat. EASD. Stockholm: Abstract [Details]
(2010) A Comparison of Gene Delivery both in vitro and in vivo, from Phosphorylcholine-Coated Stents, using Commercial and Novel Lipoplex Formulations. TERMIS-EU Meeting, Galway.
Ganly S, Hynes S, Sharif F, Barron V, McCullagh K, McHugh P, Crowley J, O'Brien T, Greiser U (2010) A Comparison of Gene Delivery both in vitro and in vivo, from Phosphorylcholine-Coated Stents, using Commercial and Novel Lipoplex Formulations. TERMIS-EU Meeting, Galway. Abstract [Details]
(2010) Gene Eluting Stents: Enhanced Vessel Healing from Viral and Non-Viral Vectors. Arteriosclerosis, Thrombosis and Vascular Biology 2010 Scientific Sessions, Hosted by the American Heart Association, San Francisco.
Hynes SO, Sharif F, McCullagh K, Ganly S, Crowley J, Greiser U, McHugh P, O'Brien T (2010) Gene Eluting Stents: Enhanced Vessel Healing from Viral and Non-Viral Vectors. Arteriosclerosis, Thrombosis and Vascular Biology 2010 Scientific Sessions, Hosted by the American Heart Association, San Francisco. Abstract [Details]
(2010) The role of osteopontin in endothelial progenitor cell function.
Vaughan, EE,Duffy, A,O'Brien, T (2010) The role of osteopontin in endothelial progenitor cell function. Abstract [Details]
(2010) Pain self-efficacy and pain catastrophising predict depression in people with painful diabetic neuropathy.
McGuire, BE,Treacy, M,Sarma, K,Dinneen, S,O'Brien, T,Dunne, F (2010) Pain self-efficacy and pain catastrophising predict depression in people with painful diabetic neuropathy. Abstract [Details]
(2010) Osteogenic and chondrogenic potential of blood vessel derived stem cells.
Leszczynska, A,O'Doherthy, A,O'Brien, T,Murphy, M (2010) Osteogenic and chondrogenic potential of blood vessel derived stem cells. Abstract [Details]
(2010) Tracking Mesenchymal Stem Cell Homing to the Infarcted Heart after Intracoronary, Intravenous and Intramyocadial Delivery.
Duffy, G,Kavanagh, C,Coleman, C,Murphy, M,O'Brien, T,Barrett, HH,Barry, F,Liu, Z (2010) Tracking Mesenchymal Stem Cell Homing to the Infarcted Heart after Intracoronary, Intravenous and Intramyocadial Delivery. Abstract [Details]
(2010) EPCs: are they good for the sole?.
O'Loughlin, A,Kulkarni, M,Dockery, P,Pandit, A,O'Brien, T (2010) EPCs: are they good for the sole?. Abstract [Details]
(2010) The role of MRP8/14 in in stent restenosis in the diabetic rat.
Stocca, A,Duffy, A,O'Toole, D,O'Brien, T (2010) The role of MRP8/14 in in stent restenosis in the diabetic rat. Abstract [Details]
(2010) Enhancing Stem Cell Retention within a Functionalised Scaffold after Implantation in an Infarcted Heart. Oral presentation at TERMIS-NA, Orlando.
Carolyn Holladay, Aoife Duffy, Xizhe Chen, Timothy O'Brien, Michael Sefton, Abhay Pandit (2010) Enhancing Stem Cell Retention within a Functionalised Scaffold after Implantation in an Infarcted Heart. Oral presentation at TERMIS-NA, Orlando. Abstract [Details]
(2010) Interleukin-10 Transfection Improves Stem Cell Retention within a scaffold after Implantation. ESB.
Holladay C, Sefton M, Dockery P, Murphy M, O'Brien T (2010) Interleukin-10 Transfection Improves Stem Cell Retention within a scaffold after Implantation. ESB. Tampere: Abstract [Details]
(2010) The role of osteopontin in endothelial progenitor cell function. EASD.
Vaughan E, Duffy A, O'Brien T (2010) The role of osteopontin in endothelial progenitor cell function. EASD. Stockholm: Abstract [Details]
(2010) The role of MRP8 and MRP14 in in stent restenosis in the diabetic rat.
Stocca, A,O'Toole, D,Duffy, A,O'Brien, T (2010) The role of MRP8 and MRP14 in in stent restenosis in the diabetic rat. Abstract [Details]
(2010) Should I stay or should I go?-hospitalisation rates among patients with newly diagnosed type 1 diabetes.
Tuohy, S,Ryan, J,Matiullah, S,Cunningham, A,Burke, H,Giblin, L,Bell, M,Dunne, F,O'Brien, T,Dinneen, SF (2010) Should I stay or should I go?-hospitalisation rates among patients with newly diagnosed type 1 diabetes. Abstract [Details]
(2009) Glycaemic, blood pressure and lipid control in type 1 diabetes. 69th Scientific Sessions, American Diabetes Association, New Orleans.
Javid S, O'Sullivan EP, Dineen S, O'Brien T, Dunne F (2009) Glycaemic, blood pressure and lipid control in type 1 diabetes. 69th Scientific Sessions, American Diabetes Association, New Orleans. Abstract [Details]
(2009) Sodium Iodide Symporter (NIS) mediated tracking of Mesenchymal Stem Cell (MSC) migration to breast tumours in vivo. Oral presentation at European Society for Gene and Cell Therapy, Hannover Germany.
RM Dwyer, J Ryan, R Havelin, JC Morris, C O'Flatharta, G Duffy, B Miller, Z Liu, HH Barrett, M Murphy, FP Barry, T O'Brien and MJ Kerin (2009) Sodium Iodide Symporter (NIS) mediated tracking of Mesenchymal Stem Cell (MSC) migration to breast tumours in vivo. Oral presentation at European Society for Gene and Cell Therapy, Hannover Germany. Abstract [Details]
(2009) Type 1 bovine collagen is an effective biomaterial for topical delivery of peripheral blood mononuclear cells and circulating angiogenic cells. Irish Society for Cell and Gene Therapy conference, Cork.
O'Loughlin A, Kulkumari M, Ward J, Pandit A, O'Brien T (2009) Type 1 bovine collagen is an effective biomaterial for topical delivery of peripheral blood mononuclear cells and circulating angiogenic cells. Irish Society for Cell and Gene Therapy conference, Cork. Abstract [Details]
(2009) Osteopontin Stimulates Secretion of Angiogenic Proteins in Endothelial Cells. Oral Presentation, Irish Society for Cell and Gene Therapy conference, Cork.
Vaughan E, Duffy A, O'Brien T (2009) Osteopontin Stimulates Secretion of Angiogenic Proteins in Endothelial Cells. Oral Presentation, Irish Society for Cell and Gene Therapy conference, Cork. Abstract [Details]
(2009) Osteopontin Stimulates Secretion of Angiogenic Proteins in Endothelial Cells. Oral Presentation, American Heart Association Scientific Sessions.
Vaughan E, Duffy A, O'Brien T (2009) Osteopontin Stimulates Secretion of Angiogenic Proteins in Endothelial Cells. Oral Presentation, American Heart Association Scientific Sessions. Abstract [Details]
(2009) Secreted Frizzled Protein 2, a Cardioprotective Gene is Upregulated in Mesenchymal Stem Cells Following Engraftment in the Injured Myocardium.
Kavanagh, C,Duffy, GP,Mashayekhi, K,O' Brien, T,Barry, F (2009) Secreted Frizzled Protein 2, a Cardioprotective Gene is Upregulated in Mesenchymal Stem Cells Following Engraftment in the Injured Myocardium. Abstract [Details]
(2009) European Regulatory Compliance in the Manufacture of Human Cellular Therapeutic Products. International Society for Cell and Gene Therapy, Cork.
Duffy K, Madden K, O'Brien T, Barry FB (2009) European Regulatory Compliance in the Manufacture of Human Cellular Therapeutic Products. International Society for Cell and Gene Therapy, Cork. Abstract [Details]
(2009) Secreted Frizzled Protein 2, a Cardioprotective Gene is Upregulated in Mesenchymal Stem Cells Following Engraftment in the Injured Myocardium. American Heart Association, National Scientific Session.
Kavanagh C, Duffy G, Mashayekhi K, O' Brien T, Barry FB (2009) Secreted Frizzled Protein 2, a Cardioprotective Gene is Upregulated in Mesenchymal Stem Cells Following Engraftment in the Injured Myocardium. American Heart Association, National Scientific Session. Abstract [Details]
(2009) Mesenchymal Stem Cells (MSCs) meay promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Oral presentation at the Society of Academic and Research Surgeons (SARS), Cambridge, UK.
FT Martin, RM Dwyer, JM Murphy, N Miller, FP Barry, T O'Brien, MJ Kerin (2009) Mesenchymal Stem Cells (MSCs) meay promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Oral presentation at the Society of Academic and Research Surgeons (SARS), Cambridge, UK. Abstract [Details]
(2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer cells support induction of Epithelial – Mesenchymal Transition (EMT). Irish Association for Cancer Research, Athlone.
FT Martin, RM Dwyer, J Kelly, JM Murphy, N Miller, E Hennessy, C Curran, FP Barry, T O'Brien, MJ Kerin (2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer cells support induction of Epithelial – Mesenchymal Transition (EMT). Irish Association for Cancer Research, Athlone. Abstract [Details]
(2009) The impact of obesity on attainment of ADA targets in patients with type 2 diabetes. 69th Scientific Sessions, American Diabetes Association, New Orleans.
Javid S, O'Sullivan EP, Dinneen S, O'Brien T, Dunne F (2009) The impact of obesity on attainment of ADA targets in patients with type 2 diabetes. 69th Scientific Sessions, American Diabetes Association, New Orleans. Abstract [Details]
(2009) Towards development of safe and efficient fibrin based topical gene delivery systems for angiogenesis in compromised wound healing. 36th Annual Meeting & Exposition of the Controlled Release Society, Copenhagen.
M Kulkarni, A Breen, U Greiser, T O'Brien, A Pandit (2009) Towards development of safe and efficient fibrin based topical gene delivery systems for angiogenesis in compromised wound healing. 36th Annual Meeting & Exposition of the Controlled Release Society, Copenhagen. Abstract [Details]
(2009) IMPLEMENTATION OF ESH-ESC GUIDELINES FOR THE MANAGEMENT OF ARTERIAL HYPERTENSION IN AN IRISH PRIMARY CARE SETTING.
Mieske, K,Flaherty, G,O'Brien, T (2009) IMPLEMENTATION OF ESH-ESC GUIDELINES FOR THE MANAGEMENT OF ARTERIAL HYPERTENSION IN AN IRISH PRIMARY CARE SETTING. Abstract [Details]
(2009) Recognition of tropical illness in the returned traveller by healthcare professionals working in an Irish university teaching hospital.
Flaherty, G,Scott, A,O'Brien, T (2009) Recognition of tropical illness in the returned traveller by healthcare professionals working in an Irish university teaching hospital. Abstract [Details]
(2009) Comparison of viral and non-viral gene delivery from a coronary artery stent.
Hynes, S,Sharif, F,McCullagh, K,Ganly, S,Greiser, U,McHugh, P,Crowley, J,O'Brien, T (2009) Comparison of viral and non-viral gene delivery from a coronary artery stent. Abstract [Details]
(2009) Lentiviral vector treatment of the inhibitory spinal cord injury environment in vitro and in vivo.
Donnelly, E,McMahon, S,McGinley, L,Windebank, A,O'Brien, T (2009) Lentiviral vector treatment of the inhibitory spinal cord injury environment in vitro and in vivo. Abstract [Details]
(2009) Stent-based Liposomal Gene Delivery: Characterization of Target Cell Population, Pattern of Expression and Therapeutic Potential of Lipostents.
Sharif, F,Hynes, SO,McCullagh, K,Ganly, S,Greiser, U,Crowley, J,McHugh, P,Daly, K,O'Brien, T (2009) Stent-based Liposomal Gene Delivery: Characterization of Target Cell Population, Pattern of Expression and Therapeutic Potential of Lipostents. Abstract [Details]
(2009) Osteopontin Stimulates Secretion of Angiogenic Proteins in Endothelial Progenitor Cells.
Vaughan, EE,Duffy, A,O'Brien, T (2009) Osteopontin Stimulates Secretion of Angiogenic Proteins in Endothelial Progenitor Cells. Abstract [Details]
(2009) AN ASTROCYTE-DORSAL ROOT GANGLION CO-CULTURE MODEL TO ASSESS NEURITE OUTGROWTH FROM LENTIVIRAL VECTOR EXPRESSED NEUROTROPHIN-3.
McMahon, S,Rooney, G,Donnelly, E,O'Brien, T,Fraher, J,Windebank, A,Dockery, P,Hampton, D,Strappe, P (2009) AN ASTROCYTE-DORSAL ROOT GANGLION CO-CULTURE MODEL TO ASSESS NEURITE OUTGROWTH FROM LENTIVIRAL VECTOR EXPRESSED NEUROTROPHIN-3. Abstract [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines.
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. Abstract [Details]
(2009) Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: Stimulation of epithelial to mesenchymal transition (EMT). American Association for Cancer Research, Denver, Colarado, USA.
FT Martin, RM Dwyer, JM Murphy, N Miller, C Curran, E Hennessy, FP Barry, T O'Brien, MJ Kerin (2009) Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: Stimulation of epithelial to mesenchymal transition (EMT). American Association for Cancer Research, Denver, Colarado, USA. Abstract [Details]
(2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Oral presentation at Sir Peter Freyer Surgical Symposium, Galway.
JC Kelly, RM Dwyer, M Murphy, FP Barry, T O'Brien and MJ Kerin (2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Oral presentation at Sir Peter Freyer Surgical Symposium, Galway. Abstract [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGFß and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Conference (ECCO), Berlin.
JC Kelly, RM Dwyer, M Murphy, FP Barry, T O'Brien and MJ Kerin (2009) Mesenchymal Stem Cell (MSC) secretion of TGFß and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Conference (ECCO), Berlin. Abstract [Details]
(2009) Single Chain Antibodies from Chicken Immune Phage Display Libraries: Reagents for Regenerative Medicine Applications and Targeting Devices for Anti - Metastasis Therapeutics. 17th Annual Conference of the European Society of Gene and Cellular Therapy, Hannover, Germany.
Bowes T, Greiser U, Murphy M, O'Brien T, Barry F (2009) Single Chain Antibodies from Chicken Immune Phage Display Libraries: Reagents for Regenerative Medicine Applications and Targeting Devices for Anti - Metastasis Therapeutics. 17th Annual Conference of the European Society of Gene and Cellular Therapy, Hannover, Germany. Abstract [Details]
(2009) Towards development of safe and efficient fibrin based topical gene delivery stytems for angiogenesis in compromised wound healing. Oral presentation at the 5th Joint Meeting of The European Tisue Repair Society and The Wound Healing Society (ETRS-WHS), Limoges, France.
M Kulkarni, A Breen, U Greiser, T O'Brien, A Pandit (2009) Towards development of safe and efficient fibrin based topical gene delivery stytems for angiogenesis in compromised wound healing. Oral presentation at the 5th Joint Meeting of The European Tisue Repair Society and The Wound Healing Society (ETRS-WHS), Limoges, France. Abstract [Details]
(2009) Antibodies Generated Using Chicken Immune Phage Display, their Role in Regenerative Medicine and as Potential Therapeutics in Metastasis. 3rd Annual Conference of the Irish Society of Gene and Cellular Therapy 2009, Cork, Ireland.
Bowes T, Greiser U, Finlay J, O'Brien T and Barry F (2009) Antibodies Generated Using Chicken Immune Phage Display, their Role in Regenerative Medicine and as Potential Therapeutics in Metastasis. 3rd Annual Conference of the Irish Society of Gene and Cellular Therapy 2009, Cork, Ireland. Abstract [Details]
(2009) Collagen is an effective biomaterial for cell delivery to a diabetic wound. Irish Endocrine Society Meeting, Cork.
O'Loughlin A, Kulkumari M, Ward J, Pandit A, O'Brien T (2009) Collagen is an effective biomaterial for cell delivery to a diabetic wound. Irish Endocrine Society Meeting, Cork. Abstract [Details]
(2009) Fibrin-lipoplex system for controlled delivery of multiple genes. Oral Presentation at the 36th Annual Meeting and Exposition of the Controlled Release Society, Copenhagen, Denmark.
M Kulkarni, A Breen, U Greiser, T O'Brien, A Pandit (2009) Fibrin-lipoplex system for controlled delivery of multiple genes. Oral Presentation at the 36th Annual Meeting and Exposition of the Controlled Release Society, Copenhagen, Denmark. Abstract [Details]
(2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium, Limerick.
FT Martin, RM Dwyer,TP Griffin, JM Murphy, FP Barry, T O'Brien, MJ Kerin (2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium, Limerick. Abstract [Details]
(2008) Evaluation of Cartilage Repair Strategies using an Osteoarthritic Explant Model. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina, USA.
Curtin, C, Murphy, M, O'Flatharta, C, Curtin, W, Dockery, P, O'Brien, T, Barry, F (2008) Evaluation of Cartilage Repair Strategies using an Osteoarthritic Explant Model. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina, USA. Abstract [Details]
(2008) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2008) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA. Abstract [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT), Boston, Massacheusetts, USA.
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien, MJ Kerin (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT), Boston, Massacheusetts, USA. Abstract [Details]
(2008) Regeneration of injured spinal cord neurons through implantable polymer bridges using a combined approach of neurotrophic support and glial scar inhibition. ISGCT Annual Conference, UCC.
Nicolas Madigan, Siobhan McMahon, Thomas Ritter, Gemma Rooney, Frank Barry, Anthony Windebank, Timothy O'Brien (2008) Regeneration of injured spinal cord neurons through implantable polymer bridges using a combined approach of neurotrophic support and glial scar inhibition. ISGCT Annual Conference, UCC. Abstract [Details]
(2008) Targeting Stem Cells for Cartilage Repair. ISGCT Annual Conference, University College Cork.
Curtin, Caroline, Murphy, Mary, Curtin, William, Docker, Peter, O'Flatharta, Cathal, O'Brien, Timothy, Barry, Frank (2008) Targeting Stem Cells for Cartilage Repair. ISGCT Annual Conference, University College Cork. Abstract [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. ISGCT Annual Conference.
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. ISGCT Annual Conference. UCC: Abstract [Details]
(2008) MHC class I dependent lysis of allogenic MSCs by cytotoxic T cells is reduced in Ad-Ox18sc 'intrabody' expressing MSCs. ISGCT Annual Conference.
Schu S, O'Flynn L, Shaw G, Busch A, Volk HD, Barry F, Murphy M, O'Brien T, Ritter T (2008) MHC class I dependent lysis of allogenic MSCs by cytotoxic T cells is reduced in Ad-Ox18sc 'intrabody' expressing MSCs. ISGCT Annual Conference. UCC: Abstract [Details]
(2008) Regeneration of Injured Spinal Cord Neurons through Implantable Polymer Bridges Using A Combined Approach Of Neurotrophic Support And Glial Scar Inhibition. Neuroscience Ireland Meeting.
N Madigan, G Rooney, T Ritter, F Barry, A Windebank, T O'Brien, S McMahon (2008) Regeneration of Injured Spinal Cord Neurons through Implantable Polymer Bridges Using A Combined Approach Of Neurotrophic Support And Glial Scar Inhibition. Neuroscience Ireland Meeting. NUI Galway: Abstract [Details]
(2008) Analysis Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. Neuroscience Ireland Meeting.
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Lisa McGinley, Timothy O'Brien (2008) Analysis Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. Neuroscience Ireland Meeting. NUI Galway: Abstract [Details]
(2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumors. European Association for Cancer Research (EACR) Lyon, France.
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumors. European Association for Cancer Research (EACR) Lyon, France. Abstract [Details]
(2008) Complexing DNA with Dendrimers to Enhance Gene Delivery from Collagen Scaffolds to Mesenchymal Stem Cells. Podium presentation at the Tissue Engineering and Regenerative Medicine International Society, Porto, Portugal.
Holladay, C, Murphy, M, Greiser, U, O'Brien, T, Pandit, A (2008) Complexing DNA with Dendrimers to Enhance Gene Delivery from Collagen Scaffolds to Mesenchymal Stem Cells. Podium presentation at the Tissue Engineering and Regenerative Medicine International Society, Porto, Portugal. Abstract [Details]
(2008) Bio-molecular Interaction between Fibrin and Lipoplexes Results in Extended Release of Plasmid DNA. Tissue Engineering and Regenerative Medicine International Society, Porto, Portugal.
Kulkarni, M, Breen A, Greiser, U, O'Brien T, Pandit, A (2008) Bio-molecular Interaction between Fibrin and Lipoplexes Results in Extended Release of Plasmid DNA. Tissue Engineering and Regenerative Medicine International Society, Porto, Portugal. Abstract [Details]
(2008) Development of a carbon nanotube based Electroactive scaffold for production of a tissue engineered cardio patch. American Heart Association's Scientific Sessions.
Joseph N Mackle, David Blond, Frank Barry, Timothy O' Brien, Mary Murphy, Valerie Barron (2008) Development of a carbon nanotube based Electroactive scaffold for production of a tissue engineered cardio patch. American Heart Association's Scientific Sessions. Abstract [Details]
(2008) Development of mesenchymal stem cell targeting strategies for cartilage repair C. World Congress of Osteoarthritis, Italy.
Curtin C, Murphy M, Curtin W, Dockery P, O'Flatharta C, O'Brien T, Barry F (2008) Development of mesenchymal stem cell targeting strategies for cartilage repair C. World Congress of Osteoarthritis, Italy. Abstract [Details]
(2008) Importance of Metabolically Flexibile Mscs for Cardiac Repair. 4th Conference on Cardiovascular Cell and Gene Therapy, Mt Sinai School of Medicine.
Mylotte LM, O'Brien T (2008) Importance of Metabolically Flexibile Mscs for Cardiac Repair. 4th Conference on Cardiovascular Cell and Gene Therapy, Mt Sinai School of Medicine. Abstract [Details]
(2008) The Role of Osteopontin in Angiogenesis 4th Conference on Cardiovascular Cell and Gene Therapy, Mt. Sinai School of Medicine, Cardiovascular Institute and Center for Cardiovascular Health, NY.
Vaughan, Erin and O'Brien, T (2008) The Role of Osteopontin in Angiogenesis 4th Conference on Cardiovascular Cell and Gene Therapy, Mt. Sinai School of Medicine, Cardiovascular Institute and Center for Cardiovascular Health, NY. Abstract [Details]
(2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. ISGCT Annual Conference, UCC.
Udo Greiser, Melissa Hoare, Tyrone Bowes, Roisin Dwyer, Daniel O'Toole, Kaveh Mashayekhi, Mary Murphy, Frank Barry and Timothy O'Brien (2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. ISGCT Annual Conference, UCC. Abstract [Details]
(2008) Critical Role for Osteopontin in Endothelial Progenitor Cell (EPC) Function. International Society for Cell Therapy in Miami, FL.
Liew A, Bowes T, Coleman C, Greiser U, O'Brien T (2008) Critical Role for Osteopontin in Endothelial Progenitor Cell (EPC) Function. International Society for Cell Therapy in Miami, FL. Abstract [Details]
(2008) Investigation of chondrogenic differentiation of MSCs in a hypoxic environment. Musculoskeletal Biology & Bioengineering: Integrating Musculoskeletal Science, Proctor Academy, Andover, NH.
LA Mylotte, E Szegezdi, T O'Brien, M Murphy, C Coleman, F Barry (2008) Investigation of chondrogenic differentiation of MSCs in a hypoxic environment. Musculoskeletal Biology & Bioengineering: Integrating Musculoskeletal Science, Proctor Academy, Andover, NH. Abstract [Details]
(2008) Fibrin Delivery of Adenoviral Vector Encoding eNOS Promotes Wound Healing in a Dermal Wound Model. Poster presentation at the 8th World Biomaterials Congress, Amsterdam, Holland.
Breen, A, Dockery, P, O' Brien, T and Pandit, A (2008) Fibrin Delivery of Adenoviral Vector Encoding eNOS Promotes Wound Healing in a Dermal Wound Model. Poster presentation at the 8th World Biomaterials Congress, Amsterdam, Holland. Abstract [Details]
(2008) Viral vector mediated delivery of antioxidant and anti-apoptotic proteins. ISGCT Annual Conference, UCC.
Lisa McGinley, Daniel O'Toole, Jill McMahon, Padraig Strappe, Timothy O'Brien (2008) Viral vector mediated delivery of antioxidant and anti-apoptotic proteins. ISGCT Annual Conference, UCC. Abstract [Details]
(2008) Neural stem cells differentiate into neurons and glia following transplantation into injured rat spinal cord. Neuroscience Ireland Meeting, NUI Galway.
Siobhan S McMahon, Silke Albermann, Gemma E Rooney, Timothy O'Brien, Yolanda Garcia, Peter Dockery, Anthony J Windebank, Timothy E Allsopp, Frank P Barry (2008) Neural stem cells differentiate into neurons and glia following transplantation into injured rat spinal cord. Neuroscience Ireland Meeting, NUI Galway. Abstract [Details]
(2008) Development of a Carbon Nanotube Based Electroactive Scaffold for Production of a Tissue Engineered Cardiac Patch. AHA Scientific Sessions 2008, New Orleans.
Joseph N Mackle, David Blond, Werner Blau, Frank Barry, Timothy O' Brien, Mary Murphy, Valerie Barron (2008) Development of a Carbon Nanotube Based Electroactive Scaffold for Production of a Tissue Engineered Cardiac Patch. AHA Scientific Sessions 2008, New Orleans. Abstract [Details]
(2008) Electrical Stimulation of Mesenchymal Stem Cells in the Presence of Carbon Nanotubes.
Mooney, EJ,Mackle, JN,Barry, F,O'Brien, T,Murphy, M,Barron, V (2008) Electrical Stimulation of Mesenchymal Stem Cells in the Presence of Carbon Nanotubes. Abstract [Details]
(2008) Development of a Functional Human Osteoarthritic Explant Model for Evaluation of Cartilage Repair Strategies. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies.
Curtin, Caroline, Murphy, Mary, Curtin, William, Dockery, Peter, O'Flatharta, Cathal, O'Brien, T, Barry, Frank (2008) Development of a Functional Human Osteoarthritic Explant Model for Evaluation of Cartilage Repair Strategies. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies. Abstract [Details]
(2008) Influence of genetic modification of mesenchymal stem cells on their differentiation capacity and immunogenicity. ISGCT Annual Conference.
Aydodan, E, Cregg, M, Schu, S, Ryan, C, Murphy, M, O'Brien, T, Barry, F, Ritter, T (2008) Influence of genetic modification of mesenchymal stem cells on their differentiation capacity and immunogenicity. ISGCT Annual Conference. UCC: Abstract [Details]
(2008) Aerosol delivery of rAAV pseudotypes 2, 2/5 and 2/6. ISGCT Annual Conference.
MacLoughlin R, Higgins B, Laffey J, O'Brien T (2008) Aerosol delivery of rAAV pseudotypes 2, 2/5 and 2/6. ISGCT Annual Conference. UCC: Abstract [Details]
(2008) An ultrastructural study of the effect of silencing NG” inhibitory factor. 16th ESGCT Annual Congress Brugge, Belgium.
Siobhan McMahon, Peter Dockery, Eleanor Donnelly, John Fraher, Padraig Strappe, Timothy O'Brien (2008) An ultrastructural study of the effect of silencing NG” inhibitory factor. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs. 16th ESGCT Annual Congress Brugge, Belgium.
Udo Greiser, Melissa Hoare, Tyrone Bowes, Roisin Dwyer, Daniel O'Toole, Kaveh Mashayekhi, Mary Murphy, Timothy O'Brien, Frank Barry (2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) Mesenchymal stem cells over-expressing ephrin-B2: A potential pro-angiogenic stem cell source. 16th ESGCT Annual Congress Brugge, Belgium.
Garry Duffy, Sinead Darcy, Tabassum Ahsan, Robert M Neerem, Timothy O'Brien, Frank Barry (2008) Mesenchymal stem cells over-expressing ephrin-B2: A potential pro-angiogenic stem cell source. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) Efficient transduction of adult human and rat mesenchymal stem cells with a third genertaion HIV-1 derived lentivirus. 16th ESGCT Annual Congress Brugge, Belgium.
Barry McGrath, Timothy O'Brien (2008) Efficient transduction of adult human and rat mesenchymal stem cells with a third genertaion HIV-1 derived lentivirus. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) Electrical Stimulation of Mesenchymal Stem Cells in the Presence of Carbon Nanotubes. AHA Scientific Sessions 2008, New Orleans.
E Mooney, JN Mackle, F Barry, T O'Brien, M Murphy, V Barron (2008) Electrical Stimulation of Mesenchymal Stem Cells in the Presence of Carbon Nanotubes. AHA Scientific Sessions 2008, New Orleans. Abstract [Details]
(2008) An ultrastructural study of the effect of silencing NG2 inhibitory factor.
McMahon, S,Dockery, P,Donnelly, E,Fraher, J,Strappe, P,O'Brien, T (2008) An ultrastructural study of the effect of silencing NG2 inhibitory factor. Abstract [Details]
(2008) Effect of lentiviral vector expressing neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord.
Donnelly, E,McMahon, S,Dockery, P,Fraher, J,Strappe, P,O'Toole, D,McGinley, L,O'Brien, T (2008) Effect of lentiviral vector expressing neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord. Abstract [Details]
(2008) Influence of genetic modification of mesenchymal stem cells on their differentiation capacity and immunogenicity.
Aydogan, E,Cregg, M,Ryan, C,Murphy, M,O'Brien, T,Barry, F,Ritter, T (2008) Influence of genetic modification of mesenchymal stem cells on their differentiation capacity and immunogenicity. Abstract [Details]
(2008) Efficient transduction of adult human and rat mesenchymal stem cells with a third generation HIV-1 derived lentivirus.
McGrath, B,O'Brien, T (2008) Efficient transduction of adult human and rat mesenchymal stem cells with a third generation HIV-1 derived lentivirus. Abstract [Details]
(2008) Chromatographic purification of adenoviral vectors for gene therapy.
Eglon, M,Duffy, A,O'Brien, T,Strappe, P (2008) Chromatographic purification of adenoviral vectors for gene therapy. Abstract [Details]
(2008) Complexing DNA with dendrimers to enhance gene delivery from collagen scaffolds to mesenchymal stem cells.
Holladay, C,Murphy, M,Greiser, U,O'Brien, T,Pandit, A (2008) Complexing DNA with dendrimers to enhance gene delivery from collagen scaffolds to mesenchymal stem cells. Abstract [Details]
(2008) Stereological methods in the assessment of functionalised scaffolds in vivo.
Ghriallais, RN,Breen, A,Kulkarni, M,Dockery, P,O'Brien, T,Pandit, A (2008) Stereological methods in the assessment of functionalised scaffolds in vivo. Abstract [Details]
(2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours.
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kenn, MJ (2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours. Abstract [Details]
(2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines.
Martin, FT,Dwyer, RM,Murphy, JM,Barry, FP,O'Brien, T,Kerin, MJ (2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines. Abstract [Details]
(2008) Efficiency of lentiviral vector transduction in injured rat spinal cord: a stereological analysis.
Toal, F,Donnelly, E,O'Brien, T,Kelly, JP,Fraher, JP,Strappe, P,Dockery, P,McMahon, SS (2008) Efficiency of lentiviral vector transduction in injured rat spinal cord: a stereological analysis. Abstract [Details]
(2008) Endothelial Progenitor Cell Dysfunction in Diabetes Mellitus: A Role for Osteopontin. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA.
Liew A, Bowes T, Coleman CM, Greiser U, O'Brien T (2008) Endothelial Progenitor Cell Dysfunction in Diabetes Mellitus: A Role for Osteopontin. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA. Abstract [Details]
(2008) Mesenchymal stem cell migration in response to a myocardial infarct-produced chemokine stimulus. ISGCT Annual Conference.
Claire Kavanagh, Peter A Sloane, Roisin Dwyer, Cynthia Coleman, Timothy O'Brien Frank Barry (2008) Mesenchymal stem cell migration in response to a myocardial infarct-produced chemokine stimulus. ISGCT Annual Conference. UCC: Abstract [Details]
(2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. ISGCT Annual Conference.
Siobhan S McMahon, Silke Albermann , Gemma E Rooney, Timothy O'Brien, Yolanda Garcia, Peter Dockery, Anthony J Windebank, Timothy E Allsopp, Frank P Barry (2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. ISGCT Annual Conference. UCC: Abstract [Details]
(2008) The Role of Osteopontin in Angiogenesis. ISGCT Annual Conference.
Vaughan, Erin, Liew, A, Coleman C, O'Brien, T (2008) The Role of Osteopontin in Angiogenesis. ISGCT Annual Conference. Abstract [Details]
(2008) Allogenic mesenchymal stem cells for regenerative medicine. Oral presentation European Society of Sports Traumatology Knee Surgery and Arthroscopy (ESSKA), Porto, Portugal.
Caroline Curtin, Mary Murphy, Cynthia Coleman, William Curtin, Peter Dockery, Cathal O'Flatharta, Timothy O'Brien, Frank Barry (2008) Allogenic mesenchymal stem cells for regenerative medicine. Oral presentation European Society of Sports Traumatology Knee Surgery and Arthroscopy (ESSKA), Porto, Portugal. Abstract [Details]
(2008) EDC/NHS and PAMAM Dendrimer Cross-linked Collagen Scafold for Sustained Gene Delivery. 8th World Biomaterials Conference, The Netherlands.
Castells, R, Yao, Li, Tiong, W, Wallace, M, Ritter, T, Kelly, J, O'Brien, T, Pandit, A (2008) EDC/NHS and PAMAM Dendrimer Cross-linked Collagen Scafold for Sustained Gene Delivery. 8th World Biomaterials Conference, The Netherlands. Abstract [Details]
(2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR), Lyon, France.
FT Martin, RM Dwyer, JM Murphy, FP Barry, T O'Brien, MJ Kerin (2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR), Lyon, France. Abstract [Details]
(2008) Aerosol delivery of AAV5-gfp to the rodent lung. 16th ESGCT Annual Congress Brugge, Belgium.
Ronan Mac Loughlin, Brendan Higgins, John Laffey and Timothy O'Brien (2008) Aerosol delivery of AAV5-gfp to the rodent lung. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) Novel techniques for the retrieval of engrafted mesenchymal stem cells from the injured myocardium. ISCT Miami.
Duffy G, Kavanagh C, Mooney E, Coleman C, Bowes T, O'Brien T, Barry F (2008) Novel techniques for the retrieval of engrafted mesenchymal stem cells from the injured myocardium. ISCT Miami. Abstract [Details]
(2008) Assessment of Stem Cell Targeting Strategies in a Functional Human Osteoarthritic Explant Model. 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, California, USA.
Curtin, C, Murphy, M, O'Flatharta, C, Curtin, W, Dockery, P, O'Brien, T, Barry, F (2008) Assessment of Stem Cell Targeting Strategies in a Functional Human Osteoarthritic Explant Model. 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, California, USA. Abstract [Details]
(2008) Effect of Neural Stem Cells and Cyclosporin-A on Cellular Environment of Contused Rat Spinal Cord. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA.
McMahon S, Albermann S, Hynes J, Rooney G, Moran C, Shaw G, O'Brien T, Garcia Y, Dockery P, Windebank AJ, Allsopp TE, Barry F (2008) Effect of Neural Stem Cells and Cyclosporin-A on Cellular Environment of Contused Rat Spinal Cord. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA. Abstract [Details]
(2008) Stereological Methods in the Assessment of Functionalised Scaffolds in Vivo. Tissue Engineering and Regenerative Medicine International Society, Porto, Portugal.
Griallais, R, Breen, A, Kulkarni, M, Dockery, P, O'Brien, T, Pandit, A (2008) Stereological Methods in the Assessment of Functionalised Scaffolds in Vivo. Tissue Engineering and Regenerative Medicine International Society, Porto, Portugal. Abstract [Details]
(2008) Influence of genetic modification of mesenchymal stem cells on their differentiation capacity and immunogenicity. 16th ESGCT Annual Congress, Brugge, Belgium.
T Ritter, E Aydogan, M Cregg, S Schu, C Ryan, M Murphy, T O'Brien, F Barry (2008) Influence of genetic modification of mesenchymal stem cells on their differentiation capacity and immunogenicity. 16th ESGCT Annual Congress, Brugge, Belgium. Abstract [Details]
(2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord. 16th ESGCT Annual Congress Brugge, Belgium.
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Lisa McGinley, Timothy O'Brien (2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) Viral vector mediated delivery of antioxidant and anti-apoptotic proteins to mesenchymal stem cells. 16th ESGCT Annual Congress Brugge, Belgium.
Lisa McGinley, Daniel O'Toole, Jill McMahon, Padraig Strappe, Timothy O'Brien (2008) Viral vector mediated delivery of antioxidant and anti-apoptotic proteins to mesenchymal stem cells. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) Glial-Derived Neurotrophic Factor–Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells. Society for Neuroscience, Washington, USA.
Rooney, Gemma E, McMahon, S, Ritter, T, Garcia, Y, Madigan, N, Flugel, A, Nickander, Kim, Dockery, P, O'Brien, T, Howard, L, Windebank, AJ, Barry, F (2008) Glial-Derived Neurotrophic Factor–Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells. Society for Neuroscience, Washington, USA. Abstract [Details]
(2008) Non-Islet Cell Tumour Hypoglycaemia due to Renal Sarcoma. Irish Endocrine Society.
O'Loughlin A, Woldron-Lynch F, Cronin K, Dineen S, Griffin D, Lee J, Jaffrey S, O'Brien T, Dunne F (2008) Non-Islet Cell Tumour Hypoglycaemia due to Renal Sarcoma. Irish Endocrine Society. Abstract [Details]
(2008) Development of regenerative therapies using genetically modified cell transplantation.
O'Brien, T (2008) Development of regenerative therapies using genetically modified cell transplantation. Abstract [Details]
(2008) Purification of Adenoviral Vectors For Gene Therapy. ISGCT Annual Conference, UCC.
M Eglon, A Duffy, P Strappe, T O' Brien (2008) Purification of Adenoviral Vectors For Gene Therapy. ISGCT Annual Conference, UCC. Abstract [Details]
(2008) Analysis Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. ISGCT Annual Conference.
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Lisa McGinley, Timothy O'Brien (2008) Analysis Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. ISGCT Annual Conference. UCC: Abstract [Details]
(2008) Analysis of Neural Stem cells following transplantation into injured rat spinal cord. Neuroscience Ireland Meeting.
McMahon S, Albermann S, Rooney GE, O'Brien, T, Garcia Y, Dockery P, Windebank AJ, Allsopp TE, Barry FP (2008) Analysis of Neural Stem cells following transplantation into injured rat spinal cord. Neuroscience Ireland Meeting. NUI Galway: Abstract [Details]
(2008) Mesenchymal Stem Cells: Characterization, Therapeutic Evaluation and Manufacturing. TCES Conference, University of Nottingham.
Frank Barry, Mary Murphy, Cindy Coleman, Tim O'Brien, Margaret Rae, Karen Duffy (2008) Mesenchymal Stem Cells: Characterization, Therapeutic Evaluation and Manufacturing. TCES Conference, University of Nottingham. Abstract [Details]
(2008) Purification of Adenoviral Vectors For Gene Therapy. 16th ESGCT Annual Congress Brugge, Belgium.
M Eglon, A Duffy, P Strappe, T O'Brien (2008) Purification of Adenoviral Vectors For Gene Therapy. 16th ESGCT Annual Congress Brugge, Belgium. Abstract [Details]
(2008) The metastatic potential of circulating Breast Cancer Cells is promoted through interactions with Mesenchymal Stem Cells. San Antonio Breast Cancer Symposium, San Antonio, Texas, USA.
FT Martin, RM Dwyer, JM Murphy, FP Barry, T O'Brien, MJ Kerin (2008) The metastatic potential of circulating Breast Cancer Cells is promoted through interactions with Mesenchymal Stem Cells. San Antonio Breast Cancer Symposium, San Antonio, Texas, USA. Abstract [Details]
(2007) Evaluation of Stem Cell Targeting Strategies to Osteoarthritic Cartilage using an Explant Culture System. Irish Society of Gene & Cell Therapy Conference, Galway.
Curtin C, Murphy M, O'Flatharta C, Curtin W, Dockery P, O'Brien T, Barry F (2007) Evaluation of Stem Cell Targeting Strategies to Osteoarthritic Cartilage using an Explant Culture System. Irish Society of Gene & Cell Therapy Conference, Galway. Abstract [Details]
(2007) Optimization of aerosol delivery to the lungs of Sprague-Dawley rat, an in vitro study of aerosol performance. International Society for Aerosols in Medicine (ISAM), 16th Congress, Vinci Congress Center.
MacLoughlin R, Higgins B, Laffey J, O' Brien T (2007) Optimization of aerosol delivery to the lungs of Sprague-Dawley rat, an in vitro study of aerosol performance. International Society for Aerosols in Medicine (ISAM), 16th Congress, Vinci Congress Center. Tours, France: Abstract [Details]
(2007) A systematic approach to maximising aerosol delivery of adeno-associated viral (AAV) vector to the lungs. British Association for Lung Research (BALR), 'Gene and Stem Cell Therapies for Lung Diseases', National University of Ireland, Maynooth, Ireland.
MacLoughlin R, Higgins B, Laffey J, O'Brien T (2007) A systematic approach to maximising aerosol delivery of adeno-associated viral (AAV) vector to the lungs. British Association for Lung Research (BALR), 'Gene and Stem Cell Therapies for Lung Diseases', National University of Ireland, Maynooth, Ireland. Abstract [Details]
(2007) Down-regulation of MHC class I on mesenchymal stem cells protects them from T-cell mediated cytotoxicity in an inflammatory surrounding. 1st meeting of the ISGCT, Galway, Ireland.
Schu S, O'Flynn L, Shaw G, Busch A, Volk HD, Murphy M, O'Brien T, Ritter T (2007) Down-regulation of MHC class I on mesenchymal stem cells protects them from T-cell mediated cytotoxicity in an inflammatory surrounding. 1st meeting of the ISGCT, Galway, Ireland. Abstract [Details]
(2007) Efficiency of lentiviral vector transduction in injured rat spinal cord, A stereological analysis.  Meeting of the Anatomical Society of Great Britain and Ireland, Durham, UK.
Toal F, Donnelly E, O'Brien T, Kelly JP, Fraher JP, Strappe P, Dockery P, McMahon SS (2007) Efficiency of lentiviral vector transduction in injured rat spinal cord, A stereological analysis.  Meeting of the Anatomical Society of Great Britain and Ireland, Durham, UK. Abstract [Details]
(2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours.
Dwyer, RM,Barry, FP,O'Brien, T,Kerin, MJ (2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. Abstract [Details]
(2007) A cross-linked collagen scaffold as a vehicle for gene delivery.
Vinas, CR,Breen, A,Damodaran, G,Ritter, T,O'Brien, T,Pandit, A (2007) A cross-linked collagen scaffold as a vehicle for gene delivery. Abstract [Details]
(2007) Non-viral genetic modification of stem cells. 10th American Society of Gene Therapy, Seattle, Washington, USA.
Hoare M, Greiser U, Barry F, O'Brien T (2007) Non-viral genetic modification of stem cells. 10th American Society of Gene Therapy, Seattle, Washington, USA. Abstract [Details]
(2007) Deleterious effect of hydrocortisone on endothelial progenitor cell number and function. Oral Presentation in Irish Endocrine Society 32nd Annual Meeting, Dublin, Ireland.
McDermott JH, Liew A, MacCarthy F, Sheahan J, Logie JJ, Hadoke PW, Walker BR, O'Brien T (2007) Deleterious effect of hydrocortisone on endothelial progenitor cell number and function. Oral Presentation in Irish Endocrine Society 32nd Annual Meeting, Dublin, Ireland. Abstract [Details]
(2007) D, Murphy M, O'Brien T, Ritter T. Down-regulation of MHC class I protects mesenchymal stem cells against T-cell mediated cytotoxicity in an inflammatory surrounding, 3rd World Congress on Regenerative Medicine, Leipzig, Germany.
Schu S, O'Flynn L, Shaw G, Busch A, Volk H (2007) D, Murphy M, O'Brien T, Ritter T. Down-regulation of MHC class I protects mesenchymal stem cells against T-cell mediated cytotoxicity in an inflammatory surrounding, 3rd World Congress on Regenerative Medicine, Leipzig, Germany. Abstract [Details]
(2007) A Cross- Linked Collagen Scaffold as a Vehicle for Gene Delivery. Tissue Engineering International and Regenerative Medicine Society, London, UK.
Viñas Castells R, Breen A, Damodaran G, Ritter T, O'Brien T, Pandit A (2007) A Cross- Linked Collagen Scaffold as a Vehicle for Gene Delivery. Tissue Engineering International and Regenerative Medicine Society, London, UK. Abstract [Details]
(2007) Investigation of non-viral gene delivery to the vasculature using a polymer-stent platform to combat ISR: A Bioengineering Approach. Irish Society For Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
Ganly S, Hopkins C, McMahon J, Barron V, McHugh PE, O'Brien T (2007) Investigation of non-viral gene delivery to the vasculature using a polymer-stent platform to combat ISR: A Bioengineering Approach. Irish Society For Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) Effects of aerosolisation on integrity of plasmid DNA, liposomally encased plasmid DNA, protein and siRNA using Aeroneb Pro Nebuliser. British Assosiation for Lung Research, Maynooth, Ireland.
Purcell JC, Power J, O'Brien T, O'Dea S (2007) Effects of aerosolisation on integrity of plasmid DNA, liposomally encased plasmid DNA, protein and siRNA using Aeroneb Pro Nebuliser. British Assosiation for Lung Research, Maynooth, Ireland. Abstract [Details]
(2007) Evaluation of a Novel Biomaterial to Enhance Adhesion of Mesenchymal Stem Cells to Osteoarthritic Cartilage. Irish Society of Gene & Cell Therapy Conference Galway.
Curtin C, Scarpa T, Paoletti S, Curtin W, Dockery P, O'Brien T, Barry F, Murphy M (2007) Evaluation of a Novel Biomaterial to Enhance Adhesion of Mesenchymal Stem Cells to Osteoarthritic Cartilage. Irish Society of Gene & Cell Therapy Conference Galway. Abstract [Details]
(2007) Effect of Lentiviral Vector Expressing Neurotrophin-3 on Dorsal Root Ganglia Neurite Outgrowth. 8th European meeting on glial cell function in health and disease, London, UK.
Donnelly E, McMahon SS, Strappe P,  Rooney G, Fraher JP, Dockery P, O'Brien T (2007) Effect of Lentiviral Vector Expressing Neurotrophin-3 on Dorsal Root Ganglia Neurite Outgrowth. 8th European meeting on glial cell function in health and disease, London, UK. Abstract [Details]
(2007) Retrieval of Engrafted Mesenchymal Stem Cells form the Injured Myocardium. 13th Annual Meeting of the International Society for Cellular Therapy, Sydney, Australia.
Duffy, G, Kavanagh, C, Sloane, P, Mooney, E, Bowes, T, O'Brien, T, Barry, F (2007) Retrieval of Engrafted Mesenchymal Stem Cells form the Injured Myocardium. 13th Annual Meeting of the International Society for Cellular Therapy, Sydney, Australia. Abstract [Details]
(2007) Angiogenic Interactions between Mesenchymal Stem Cells and Vascular Cells. Tissue Engineering and Development, Keystone, Colorado, USA.
Duffy G, Ahsan T, O'Brien T, Barry F, Nerem R (2007) Angiogenic Interactions between Mesenchymal Stem Cells and Vascular Cells. Tissue Engineering and Development, Keystone, Colorado, USA. Abstract [Details]
(2007) Viral vector mediated protection from oxidative stress using antioxidant enzymes. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
McGinley L, O'Toole D, Strappe P, O'Brien T (2007) Viral vector mediated protection from oxidative stress using antioxidant enzymes. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) EDC Cross-Linked Collagen Scaffold as a Vehicle for Gene Delivery. 21st European Conference on Biomaterials, Brighton, UK.
Viñas Castells R, Breen A, Damodaran G, Ritter T, O'Brien T, Pandit A (2007) EDC Cross-Linked Collagen Scaffold as a Vehicle for Gene Delivery. 21st European Conference on Biomaterials, Brighton, UK. Abstract [Details]
(2007) Detailed Flow Cytometric Analysis of early endothelial progenitor cells demonstrates their heterogenous composition. 13th Annual Meeting of the International Society for Cellular Therapy.
Bowes T, Greiser U, Barry F, O'Brien T (2007) Detailed Flow Cytometric Analysis of early endothelial progenitor cells demonstrates their heterogenous composition. 13th Annual Meeting of the International Society for Cellular Therapy. Sydney, Australia: Abstract [Details]
(2007) Stem Cell Delivery to a Functional Osteoarthritic Explant Model. 2nd Mesenchymal Stem Cell Meeting.
Curtin C, Murphy M, O'Flatharta C, Curtin W, Dockery P, O'Brien T, Barry F (2007) Stem Cell Delivery to a Functional Osteoarthritic Explant Model. 2nd Mesenchymal Stem Cell Meeting. York, UK: Abstract [Details]
(2007) Evaluation of adult Stem Cell Targeting Strategies in goat and human osteoarthritic models. Proceedings of the 5th International Society for Stem Cell Research, Cairns, Australia.
Curtin C, Murphy, M, O'Flatharta, C, Curtin, W, Dockery, P, O'Brien T, Barry F (2007) Evaluation of adult Stem Cell Targeting Strategies in goat and human osteoarthritic models. Proceedings of the 5th International Society for Stem Cell Research, Cairns, Australia. Abstract [Details]
(2007) Chitlac: A Novel Biomaterial to Promote Adhesion of Mesenchymal Stem Cells to Osteoarthritic Cartilage. 13th Annual Meeting of the International Society for Cellular Therapy, Sydney, Australia.
Curtin CM, Scarpa T, Paoletti S, Curtin W, Dockery P, O'Brien T, Barry F, Murphy M (2007) Chitlac: A Novel Biomaterial to Promote Adhesion of Mesenchymal Stem Cells to Osteoarthritic Cartilage. 13th Annual Meeting of the International Society for Cellular Therapy, Sydney, Australia. Abstract [Details]
(2007) Liposomes and Mesenchymal Stem Cells. Proceedings of the Inaugaral Irish society for Gene and Cell therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
Hoare M, Greiser U, Barry F, O'Brien T (2007) Liposomes and Mesenchymal Stem Cells. Proceedings of the Inaugaral Irish society for Gene and Cell therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research. Cairns, Australia: Abstract [Details]
(2007) Effect of lentiviral vector expressing neurotrophin-3 on neurite outgrowth following spinal cord injury. Irish Society for Gene and Cell Therapy Meeting, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
McMahon SS, Donnelly E, Fraher JP, Dockery P, O'Brien T, Strappe P (2007) Effect of lentiviral vector expressing neurotrophin-3 on neurite outgrowth following spinal cord injury. Irish Society for Gene and Cell Therapy Meeting, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) AAV-medaited delivery of paraoxonase 1 (PON1) to the apoE-/- mouse as gene therapy for atherosclerosis. 25th Annual Meeting American Society of Gene Therapy, Seattle, USA.
O'Doherty A, Rosenblat M, Aviram M, O'Brien T (2007) AAV-medaited delivery of paraoxonase 1 (PON1) to the apoE-/- mouse as gene therapy for atherosclerosis. 25th Annual Meeting American Society of Gene Therapy, Seattle, USA. Abstract [Details]
(2007) A study on the effects of aerosolization of plasmid DNA, Liposomally encased plasmid DNA, and siRNA degradation using the Aeroneb lab Pro Nebuliser. International Society for Aerosols in Medicine (ISAM), 16th Congress, Vinci Congress Center, Tours, France.
Purcell JC, MacLoughlin R, Duffy C, Power J, O'Brien T, O'Dea S (2007) A study on the effects of aerosolization of plasmid DNA, Liposomally encased plasmid DNA, and siRNA degradation using the Aeroneb lab Pro Nebuliser. International Society for Aerosols in Medicine (ISAM), 16th Congress, Vinci Congress Center, Tours, France. Abstract [Details]
(2007) Effects of aerosolisation on integrity of plasmid DNA, liposomally encased plasmid DNA, protein and siRNA using Aeroneb Pro Nebuliser. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
Purcell JC, Power J, O'Brien T, O'Dea S (2007) Effects of aerosolisation on integrity of plasmid DNA, liposomally encased plasmid DNA, protein and siRNA using Aeroneb Pro Nebuliser. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) A Tissue engineering strategies for spinal cord Injury using mesenchymal stem cells. Keystone Tissue Engineering and Developmental Biology conference Utah USA.
Rooney, GE, Moran, C, McMahon, SS, Ritter, T, Maenz, M, Fluegel, A, Dockery, P, O' Brien, T, Howard, L, Windebank, AJ, Barry, FP (2007) A Tissue engineering strategies for spinal cord Injury using mesenchymal stem cells. Keystone Tissue Engineering and Developmental Biology conference Utah USA. Abstract [Details]
(2007) Endothelial progenitor cell number: A novel concept in pathogenesis of increased cardiovascular risks in obstructive sleep apnoea syndrome. Poster presentation in British Thoracic Society UK.
Uzbeck, M, A Liew, J McDermott, D Gallagher, I Saleem, G Avalos, JJ Gilmartin, T O'Brien (2007) Endothelial progenitor cell number: A novel concept in pathogenesis of increased cardiovascular risks in obstructive sleep apnoea syndrome. Poster presentation in British Thoracic Society UK. Abstract [Details]
(2007) Effect of lentiviral vector expressing neurotrophin-3 on dorsal root ganglia neurite outgrowth.
Donnelly, E,Strappe, P,O'Brien, T,Rooney, G,Fraher, JP,Dockery, P,McMahon, S (2007) Effect of lentiviral vector expressing neurotrophin-3 on dorsal root ganglia neurite outgrowth. Abstract [Details]
(2006) In Vivo Sustained Expression of a Gene is seen from an Adenoviral Vector Gene Delivery System via a Fibrin Scaffold. Tissue Engineering and Regenerative Medicine World Congress, Pittsburg, USA.
Breen A, O'Brien T, Pandit A (2006) In Vivo Sustained Expression of a Gene is seen from an Adenoviral Vector Gene Delivery System via a Fibrin Scaffold. Tissue Engineering and Regenerative Medicine World Congress, Pittsburg, USA. Abstract [Details]
(2006) Anti-Oxidant Gene Delivery to Retinal Epithelial Cells: A Gene Therapy Approach for Macular Degeneration.
McGinley, L,Cosgrave, G,Duffy, A,O'Brien, T,Strappe, PM (2006) Anti-Oxidant Gene Delivery to Retinal Epithelial Cells: A Gene Therapy Approach for Macular Degeneration. Abstract [Details]
(2006) Lentiviral vector transduction efficiency and biosafety profile of aldult mesenchymal stem cells. American Societ of Gene Therapy 2006 Meeting, Baltimore, Maryland, USA.
McGrath, BM, O'Shea, C, Howard, L, Murphy, M, Barry, F, O'Brien, T, Strappe, P (2006) Lentiviral vector transduction efficiency and biosafety profile of aldult mesenchymal stem cells. American Societ of Gene Therapy 2006 Meeting, Baltimore, Maryland, USA. Abstract [Details]
(2006) Characterisation of the Release Rate and Binding Ability of an Adenoviral Vector to a Fibrin Scaffold for Sustained Gene Delivery. Society for Biomaterials, Pittsburgh, USA.
Breen A, Strappe P, Barker T, Hubbell J, O'Brien T, Pandit, A (2006) Characterisation of the Release Rate and Binding Ability of an Adenoviral Vector to a Fibrin Scaffold for Sustained Gene Delivery. Society for Biomaterials, Pittsburgh, USA. Abstract [Details]
(2006) Accelerated re-endothelialization in an eNOS transduced Iliac artery following gene delivery from an adenoviral eluting stent.
Sharif, F,Hynes, S,Mcmahon, J,Daly, K,Crowley, J,O'brien, T (2006) Accelerated re-endothelialization in an eNOS transduced Iliac artery following gene delivery from an adenoviral eluting stent. Abstract [Details]
(2006) Prolonged adenovirus and adeno-associated virusmediated gene delivery to rabbit iliac arteries using gene-eluting stents: A direct comparison.
Shariff, F,Hynes, SO,McMahon, J,Crowley, J,O'Brien, T (2006) Prolonged adenovirus and adeno-associated virusmediated gene delivery to rabbit iliac arteries using gene-eluting stents: A direct comparison. Abstract [Details]
(2006) NOS Isoforms, Intimal Hyperplasia and Endothelial Regeneration after Balloon Injury. American Society for Gene Therapy, Baltimore, USA.
Ronan Cooney, Sean Hynes, Sharif Faisal, Timothy O'Brien (2006) NOS Isoforms, Intimal Hyperplasia and Endothelial Regeneration after Balloon Injury. American Society for Gene Therapy, Baltimore, USA. Abstract [Details]
(2006) Engrafment of MScs into injured vasculture – A potential therapeutic approach. European Society of Gene Therapy, Athens.
O'Shea, C, O'Brien, T (2006) Engrafment of MScs into injured vasculture – A potential therapeutic approach. European Society of Gene Therapy, Athens. Abstract [Details]
(2006) Stem cell delivery to osteoarthritic tissue. ECM VII Meeting on Cartilage and Joint Repair.
Caroline Curtin, William Curtin, Mary Murphy, Timothy O'Brien, Frank Barry (2006) Stem cell delivery to osteoarthritic tissue. ECM VII Meeting on Cartilage and Joint Repair. Davos, Switzerland: Abstract [Details]
(2006) Endothelial Progenitor cells for diabetic ulcer healing. European Society of Gene Therapy, Athens.
Kealy, B, O'Brien, T (2006) Endothelial Progenitor cells for diabetic ulcer healing. European Society of Gene Therapy, Athens. Abstract [Details]
(2006) Lentiviral Vector Transduction Efficiency and Biosafety Profile of Adult Mesenchymal Stem Cells.
McGrath, BM,O'Shea, C,Howard, L,Murphy, M,Barry, F,O'Brien, T,Strappe, PM (2006) Lentiviral Vector Transduction Efficiency and Biosafety Profile of Adult Mesenchymal Stem Cells. Abstract [Details]
(2006) Induction of therapeutic angiogenesis by endothelial progenitor cells. Irish Endocrine Society 31st Annual Meeting.
Liew A, McDermott J, Sharif F, Dockery P, Gaffney M, O'Brien T (2006) Induction of therapeutic angiogenesis by endothelial progenitor cells. Irish Endocrine Society 31st Annual Meeting. Abstract [Details]
(2006) Accelerated Re-Endothelilization in eNOS Transduced Iliac Artery Following Gene Delivery from an Adenoviral Eluting Stent.
Sharif, F,Hynes, SO,Crowley, J,Daly, K,O'Brien, T (2006) Accelerated Re-Endothelilization in eNOS Transduced Iliac Artery Following Gene Delivery from an Adenoviral Eluting Stent. Abstract [Details]
(2006) Endothelial progenitor cells in Type 1 Diabetes: Declining in tandem with increasing cardiovascular risk?. Irish Endocrine Society 31st Annual Meeting.
McDermott JH, Liew A, Avalos G, O'Brien T (2006) Endothelial progenitor cells in Type 1 Diabetes: Declining in tandem with increasing cardiovascular risk?. Irish Endocrine Society 31st Annual Meeting. Abstract [Details]
(2006) Antioxidant Gene Delivery to Retinal Epithelial Cells: A Gene Therapy Approach to Macular Degeneration. ASGT conference.
Lisa McGinley, Gillian Cosgrave, Aoife Duffy, Padraig Strappe, Tim O'Brien (2006) Antioxidant Gene Delivery to Retinal Epithelial Cells: A Gene Therapy Approach to Macular Degeneration. ASGT conference. Baltimore: Abstract [Details]
(2006) NOS Isoforms, Intimal Hyperplasia and Endothelial Regeneration after Balloon Injury.
Cooney, R,Hynes, SO,Faisal, S,O'Brien, T (2006) NOS Isoforms, Intimal Hyperplasia and Endothelial Regeneration after Balloon Injury. Abstract [Details]
(2006) In vivo Adenoviral Vector Gene Delivery Via a Fibrin Scaffold. Bioengineering in Ireland, Galway.
Breen A, Barker T, Hubbell J, O'Brien T, Pandit A (2006) In vivo Adenoviral Vector Gene Delivery Via a Fibrin Scaffold. Bioengineering in Ireland, Galway. Abstract [Details]
(2005) Transcriptosome profiling of human Coronary Artery Smooth Muscle Cells in response to oxidized Low Density Lipoprotein. Royal Academy of Medicine Ireland, Section of Biomedical Sciences Summer Meeting.
Reeve J, Stenson-Cox C, Porn-Ares I, Ares M, O'Brien T, Samali A (2005) Transcriptosome profiling of human Coronary Artery Smooth Muscle Cells in response to oxidized Low Density Lipoprotein. Royal Academy of Medicine Ireland, Section of Biomedical Sciences Summer Meeting. Abstract [Details]
(2005) Absence of cytoprotection of RINm5F cells against cytokine-mediated toxicity by gene transfer of heat shock protein 70. American Diabetes Association (ADA), San Diego, California.
Bell M, Conroy S, O' Brien T (2005) Absence of cytoprotection of RINm5F cells against cytokine-mediated toxicity by gene transfer of heat shock protein 70. American Diabetes Association (ADA), San Diego, California. Abstract [Details]
(2005) Overexpression of copper-zinc superoxide dismutase (CuZnSOD) has an anti-atherogenic effect in a model for atherosclerosis. Journal of American College Surgeons.
Martin Z, Costello C, Duffy A, McLoughlin P, Fitzpatrick JM, Martin F, O'Malley MK, O'Brien T (2005) Overexpression of copper-zinc superoxide dismutase (CuZnSOD) has an anti-atherogenic effect in a model for atherosclerosis. Journal of American College Surgeons. San Francisco, USA: Abstract [Details]
(2005) Gene expression responses to endogenous anti-oxidant activity in human vascular smooth muscle cells. British Journal of Surgery, Newcastle,UK.
Martin Z, Costello C, Duffy A, McLoughlin P, Fitzpatrick JM, Martin F, O'Malley MK, O'Brien T (2005) Gene expression responses to endogenous anti-oxidant activity in human vascular smooth muscle cells. British Journal of Surgery, Newcastle,UK. Abstract [Details]
(2005) Development of Gene Therapy Approaches to Occlusive Atherosclerotic Vascular Disease using Stent-Based Gene Delivery. British Society for Gene Therapy Annual Meeting, Manchester, UK.
McMahon JM, Shariff F, O'Brien, T (2005) Development of Gene Therapy Approaches to Occlusive Atherosclerotic Vascular Disease using Stent-Based Gene Delivery. British Society for Gene Therapy Annual Meeting, Manchester, UK. Abstract [Details]
(2005) Adenoviral-mediated antioxidant overexpression: possible protective role against hyperglycemic conditions in HAEC. American Society for Gene Therapy.
Duffy A, Liew A, Samali A, O' Brien T (2005) Adenoviral-mediated antioxidant overexpression: possible protective role against hyperglycemic conditions in HAEC. American Society for Gene Therapy. Abstract [Details]
(2005) Temporo-profile of Stent Based Adenovirus Mediated Gene Therapy. Irish Journal of Medical Science.
Sharif, F, McMahon, J, Hynes, SO, Hynes, N, Liew, A, Crowley, J, O'Brien, T (2005) Temporo-profile of Stent Based Adenovirus Mediated Gene Therapy. Irish Journal of Medical Science. Abstract [Details]
(2005) Cytoprotection of RIN cells from Cytokine-Mediated toxicity by gene transfer of anti-apoptotic proteins. Irish Endocrine Society.
Bell M, Conroy S, Ritter T, Houlihan C, Samali A, O' Brien T (2005) Cytoprotection of RIN cells from Cytokine-Mediated toxicity by gene transfer of anti-apoptotic proteins. Irish Endocrine Society. Limerick: Abstract [Details]
(2005) Differential transduction of vascular endothelial cells by AAV pseudotypes. 13th Annual Congress of the European Society for Gene Therapy, Prague, Czech Republic.
Conroy S, O Brien T (2005) Differential transduction of vascular endothelial cells by AAV pseudotypes. 13th Annual Congress of the European Society for Gene Therapy, Prague, Czech Republic. Abstract [Details]
(2005) Purification of adenovirus and adeno-associated virus: comparison of novel membrane-based technology to conventional techniques. Gene Therapy.
Duffy AM, O'Doherty AM, O'Brien T, Strappe PM (2005) (2005) Purification of adenovirus and adeno-associated virus: comparison of novel membrane-based technology to conventional techniques. Gene Therapy. Abstract [Details]
(2005) Gene expression responses to endogenous antioxidant activity in human vascular smooth muscle cells.
Martin, Z,Costello, C,Duffy, A,McLoughlin, P,Fitzpatrick, JM,Martin, F,O'Malley, MK,O'Brien, T (2005) Gene expression responses to endogenous antioxidant activity in human vascular smooth muscle cells. Abstract [Details]
(2005) Human and murine cell mediated immunity to adeno-associated viruses.
Corcoran, PA,Madsen, DP,O'Brien, T,Mahon, BP (2005) Human and murine cell mediated immunity to adeno-associated viruses. Abstract [Details]
(2005) Pseudotyping of lentiviral vectors with VSV-G and Baculoviral gp64 envelope demonstrated efficient gene delivery to vascular cells. American Society for Gene Therapy, St Louis, USA.
O'Shea C, Nelson R, McMahon J, Strappe P and O'Brien T (2005) Pseudotyping of lentiviral vectors with VSV-G and Baculoviral gp64 envelope demonstrated efficient gene delivery to vascular cells. American Society for Gene Therapy, St Louis, USA. Abstract [Details]
(2005) Gene transfer into mesenchymal stem cells: a comparative study of viral and non-viral vectors. 13th Annual Congress of the European Society for Gene Therapy.
McMahon J, Conroy S, O'Shea C, Lyons M, Greiser U, Strappe P, Howard PL, Murphy M, Barry F, O'Brien T (2005) Gene transfer into mesenchymal stem cells: a comparative study of viral and non-viral vectors. 13th Annual Congress of the European Society for Gene Therapy. Prague, Czech Republic: Abstract [Details]
(2005) EPC number and functions in patients with poorly controlled, uncomplicated Type 1 Diabetes Mellitus. Irish Endocrine Society 30th Annual Meeting.
Liew A, McDermott J, Kealy B, Gaffney M, Sharif F, DeLappe E, O'Brien T (2005) EPC number and functions in patients with poorly controlled, uncomplicated Type 1 Diabetes Mellitus. Irish Endocrine Society 30th Annual Meeting. Abstract [Details]
(2005) Development and validation of an adenoviral vector purification system for cGMP production. 13th Annual Congress of the European Society for Gene Therapy.
Eglon M, Duffy A, Harte M, O Brien T, Strappe P (2005) Development and validation of an adenoviral vector purification system for cGMP production. 13th Annual Congress of the European Society for Gene Therapy. Prague, Czech Republic: Abstract [Details]
(2005) Optimisation of a Fibrin Scaffold for Viral Vector Mediated Gene Delivery. 5th Annual Meeting of Irish Angiology Society, Galway.
Breen A, Strappe P, Anilkumar T, O'Brien T, Pandit A (2005) Optimisation of a Fibrin Scaffold for Viral Vector Mediated Gene Delivery. 5th Annual Meeting of Irish Angiology Society, Galway. Abstract [Details]
(2005) Ability of a Fibrin Scaffold to Bind an Adenoviral Vector for Sustained Gene Delivery. 8th Annual Meeting of the Tissue Engineering Society International, Shanghai, 2005 and 13th Annual Congress of the European Society for Gene Therapy, Prague.
Breen A, Barker TH, Hubbell JA, O' Brien T, Pandit, A (2005) Ability of a Fibrin Scaffold to Bind an Adenoviral Vector for Sustained Gene Delivery. 8th Annual Meeting of the Tissue Engineering Society International, Shanghai, 2005 and 13th Annual Congress of the European Society for Gene Therapy, Prague. Abstract [Details]
(2005) Distinct Effects of High Glucose Conditions on endothelial cells of macrovascular and microvascular origin. Irish Angiology Society, Fifth Annual Meeting, March 2005 and Irish Endocrinology Society.
Duffy A, Liew A, O' Sullivan J, Samali A, Avalos G, O' Brien T (2005) Distinct Effects of High Glucose Conditions on endothelial cells of macrovascular and microvascular origin. Irish Angiology Society, Fifth Annual Meeting, March 2005 and Irish Endocrinology Society. Abstract [Details]
(2005) Transduction of rabbit mesenchymal stem cells with the different adeno-associated virus pseudotypes. 13th Annual Congress of the European Society for Gene Therapy, Prague, Czech Republic.
Curtin C, Conroy S, Murphy M, O'Brien T, Barry F (2005) Transduction of rabbit mesenchymal stem cells with the different adeno-associated virus pseudotypes. 13th Annual Congress of the European Society for Gene Therapy, Prague, Czech Republic. Abstract [Details]
(2005) Prospects of Gene and Cell Therapy for Vascular disease. Irish Angiology Society, 5th Annual Meeting.
O'Brien, T (2005) Prospects of Gene and Cell Therapy for Vascular disease. Irish Angiology Society, 5th Annual Meeting. Abstract [Details]
(2005) Viral Vector Mediated Gene Delivery via an Optimised Fibrin Scaffold. 19th European Conference on Biomaterials, Sorrento.
Breen A, Anilkumar T, Strappe P, O'Brien T, Pandit A (2005) Viral Vector Mediated Gene Delivery via an Optimised Fibrin Scaffold. 19th European Conference on Biomaterials, Sorrento. Abstract [Details]
(2004) Purification of Adenoviral and Adeno-Associated Viral Vectors using the Membrane-Based Methods of the Adenopure TM Kit and ViraKit. 12th Annual Congress of the ESGT, Tampere, Finland.
Duffy, A, O'Doherty, A, O'Brien, T, Strappe, P (2004) Purification of Adenoviral and Adeno-Associated Viral Vectors using the Membrane-Based Methods of the Adenopure TM Kit and ViraKit. 12th Annual Congress of the ESGT, Tampere, Finland. Abstract [Details]
(2004) Optimisation of a Fibrin Scaffold for Adenoviral Mediated Gene Delivery. Tissue Engineering Society International and the European Tissue Engineering Society, Lausanne, Switzerland.
Breen, A, Anilkumar, T, Strappe, P, O'Brien, T, Pandit, A (2004) Optimisation of a Fibrin Scaffold for Adenoviral Mediated Gene Delivery. Tissue Engineering Society International and the European Tissue Engineering Society, Lausanne, Switzerland. Abstract [Details]
(2004) Using recombinant adenoviruses to facilitate superoxide dismutase (SOD) overexpression in human vascular smooth muscle cells. Irish Medical Journal Science Limerick.
Martin Z, Costello C, Duffy A, McLoughlin P, Martin F, Fitzpatrick JM, O'Malley MK, O'Brien T (2004) (2004) Using recombinant adenoviruses to facilitate superoxide dismutase (SOD) overexpression in human vascular smooth muscle cells. Irish Medical Journal Science Limerick. Abstract [Details]
(2004) Cyclical mechanical stretch and AAV2 mediated gene transfer to cultured human vascular cells.
Sen, S,Bartlett, JS,Birney, Y,Cahill, P,O'Brien, T (2004) Cyclical mechanical stretch and AAV2 mediated gene transfer to cultured human vascular cells. Abstract [Details]
(2004) Adenoviral-mediated antioxidant gene transfer: A gene therapy approach towards diminishing pancreatic beta-cell susceptibility to cytokine-induced oxidative damage.
McCabe, CT,O'Brien, T (2004) Adenoviral-mediated antioxidant gene transfer: A gene therapy approach towards diminishing pancreatic beta-cell susceptibility to cytokine-induced oxidative damage. Abstract [Details]
(2004) Adenoviral Mediated Gene Transfer of Nitric Oxide Synthase Isoforms and Vascular Cell Proliferation. 12th Annual Congress of the ESGT, Tampere, Finland.
Cooney, R, O'Brien, T (2004) Adenoviral Mediated Gene Transfer of Nitric Oxide Synthase Isoforms and Vascular Cell Proliferation. 12th Annual Congress of the ESGT, Tampere, Finland. Abstract [Details]
(2004) Optimisation of a Fibrin Scaffold for Adenoviral Mediated Gene Delivery. Presentation at the European Society for Gene Therapy, Tampere, Finland.
Breen, A, Anilkumar, T, Starppe, P, O'Brien, T, Pandit, A (2004) Optimisation of a Fibrin Scaffold for Adenoviral Mediated Gene Delivery. Presentation at the European Society for Gene Therapy, Tampere, Finland. Abstract [Details]
(2004) Adenoviral-mediated combinatorial antioxidant gene transfer: a therapeutic approach toward augmenting pancreatic insulin-producing cell defence status against cytokine-induced oxidative damage. 12th Annual Congress of the ESGT, Tampere, Finland.
McCabe, C, O'Brien, T (2004) Adenoviral-mediated combinatorial antioxidant gene transfer: a therapeutic approach toward augmenting pancreatic insulin-producing cell defence status against cytokine-induced oxidative damage. 12th Annual Congress of the ESGT, Tampere, Finland. Abstract [Details]
(2004) Adenoviral Antioxidant Gene Transfer Therapy Approach towards diminishing pancreatic ß-Susceptibility to Cytokine-Induced Oxidative Damage. 7th Annual Meeting of the American Society of Gene Therapy.
McCabe, C, O'Brien, T (2004) Adenoviral Antioxidant Gene Transfer Therapy Approach towards diminishing pancreatic ß-Susceptibility to Cytokine-Induced Oxidative Damage. 7th Annual Meeting of the American Society of Gene Therapy. Abstract [Details]
(2004) Lentiviral-mediated gene transfer to cells of the Vasculature. 12th Annual Congress of the ESGT, Tampere, Finland.
O'Shea, C, Nelson, R, O'Brien, T, Strappe, P (2004) Lentiviral-mediated gene transfer to cells of the Vasculature. 12th Annual Congress of the ESGT, Tampere, Finland. Abstract [Details]
(2004) Modifying superoxide dismutase [SOD] activity in an experimental model for atherosclerosis. Irish Medical Journal Science Galway.
Martin Z, Costello C, Duffy A, McLoughlin P, Martin F, Fitzpatrick JM, O'Malley MK, O'Brien T (2004) Modifying superoxide dismutase [SOD] activity in an experimental model for atherosclerosis. Irish Medical Journal Science Galway. Abstract [Details]
(2004) Adenoviral mediated gene transfer of nos is of vascular cell proliferation. 7th Annual Meeting of the American Society of Gene Therapy.
Cooney R, O'Brien T (2004) Adenoviral mediated gene transfer of nos is of vascular cell proliferation. 7th Annual Meeting of the American Society of Gene Therapy. Abstract [Details]
(2004) Adenoviral mediated gene transfer of nitric oxide synthase isoforms and vascular cell proliferation. 12th Annual Congress of the ESGT, Tampere, Finland, November.
Cooney R, O'Brien, T (2004) Adenoviral mediated gene transfer of nitric oxide synthase isoforms and vascular cell proliferation. 12th Annual Congress of the ESGT, Tampere, Finland, November. Abstract [Details]
(2004) Adenoviral Mediated Gene Transfer of NOS is of Vascular Cell Proliferation. 7th Annual Meeting of the American Society of Gene Therapy.
Cooney, R, O'Brien, T (2004) Adenoviral Mediated Gene Transfer of NOS is of Vascular Cell Proliferation. 7th Annual Meeting of the American Society of Gene Therapy. Abstract [Details]
(2004) Cyclical Mechanical Stretch and AAV2 Mediated to Cultured Human Vascular Cells. 7th Annual Meeting of the American Society of Gene Therapy.
Sen, S, Bartlett, Jeff S, Cahill, P, O'Brien, T (2004) Cyclical Mechanical Stretch and AAV2 Mediated to Cultured Human Vascular Cells. 7th Annual Meeting of the American Society of Gene Therapy. Abstract [Details]
(2003) Effect of Serotype on Adeno-Assoociated Virus, (AAV) Mediated Gene Transfer to Human Vascular Cells. Registrar’s Prize Award (Royal Academy of Medicine) at RCPI, Dublin.
Sen, S, Bartlett, J, O'Brien, T (2003) Effect of Serotype on Adeno-Assoociated Virus, (AAV) Mediated Gene Transfer to Human Vascular Cells. Registrar’s Prize Award (Royal Academy of Medicine) at RCPI, Dublin. Abstract [Details]
(2003) Serotypes of Adeno-Associated Virus mediated gene transfer in vasculature. European Society of Gene Therapy, 11th Annual Congress, Edinburgh.
Sen S, Bartlett J, Akhtar Y, Adegbola T, Sultan S, O'Brien T (2003) Serotypes of Adeno-Associated Virus mediated gene transfer in vasculature. European Society of Gene Therapy, 11th Annual Congress, Edinburgh. Abstract [Details]
(2003) Effect of adenovirus associated virus (AAV) serotype on vascular gene delivery in vivo. American Heart Association, Orlando, Florida.
Sen S, Bartlett J, Akhtar Y, Sultan S, O'Brien T (2003) Effect of adenovirus associated virus (AAV) serotype on vascular gene delivery in vivo. American Heart Association, Orlando, Florida. Abstract [Details]
(2003) Adenoviral mediated gene transfer of NOS isoforms and cell proliferaton. Irish Angiology Society, 4th Annual Meeting.
Cooney R, O'Brien T (2003) Adenoviral mediated gene transfer of NOS isoforms and cell proliferaton. Irish Angiology Society, 4th Annual Meeting. Abstract [Details]
(2003) Nitric oxide synthase : Prospects for gene therapy of vascular disease. Finnish Gene Therapy Society Annual Meeting FGTS2003, University of Turku, Finland.
O'Brien T (2003) Nitric oxide synthase : Prospects for gene therapy of vascular disease. Finnish Gene Therapy Society Annual Meeting FGTS2003, University of Turku, Finland. Abstract [Details]
(2003) Adeno-Associated Virus (AAV) mediated gene delivery to vascular cells in the rabbit carotid artery module, A controlled randomised clinical trial. Sir Peter Freyer Memorial lecture and Surgical Symposium in associated with the Irish Society of Surgical Oncology.
Sen S, Bartlett J, Aktar Y, Courtney D, Sultan S, O'Brien T (2003) Adeno-Associated Virus (AAV) mediated gene delivery to vascular cells in the rabbit carotid artery module, A controlled randomised clinical trial. Sir Peter Freyer Memorial lecture and Surgical Symposium in associated with the Irish Society of Surgical Oncology. Abstract [Details]
(2003) In Viro Expression and Function of GTP Cyclohydrase I in the Rabbit Carotid Artery. FASEB.
Hynes, SO, Leslie, A, Smith, T, Darcy, R, O'Brien, T, Zvonimir, K (2003) In Viro Expression and Function of GTP Cyclohydrase I in the Rabbit Carotid Artery. FASEB. Abstract [Details]
(2003) An Update on Gene Therapy for Clinicians. Western Anasesthetic Symposium, Galway.
O'Brien, T (2003) An Update on Gene Therapy for Clinicians. Western Anasesthetic Symposium, Galway. Abstract [Details]
(2003) Gene Transfer to Restore NO Bioavailability in the Blood Vessel Wall. Molecular Medicine Seminar.
O'Brien, T (2003) Gene Transfer to Restore NO Bioavailability in the Blood Vessel Wall. Molecular Medicine Seminar. Abstract [Details]
(2003) An unusual cause of Cushing’s syndrome : a case report. Irish Endocrine Society 28th Annual Meeting.
Bell, M, Murphy J, Corcoran M, O'Brien T (2003) An unusual cause of Cushing’s syndrome : a case report. Irish Endocrine Society 28th Annual Meeting. Abstract [Details]
(2003) Effect of adeno-associated virus (AAV) serotype on vascular gene delivery in-vivo.
Sen, S,Bartlett, JS,Aktar, Y,O'Brien, T (2003) Effect of adeno-associated virus (AAV) serotype on vascular gene delivery in-vivo. Abstract [Details]
(2003) Adeno-associated virus mediated gene transfer to human vascular cell lines using serotypes 1 and 5.
Sen, S,Bartlett, J,O'Brien, T (2003) Adeno-associated virus mediated gene transfer to human vascular cell lines using serotypes 1 and 5. Abstract [Details]
(2003) In vivo expression and function of GTP cyclohydrolase I in the rabbit carotid artery.
Hynes, SO,Smith, LA,Richardson, DM,Kovedsi, I,O'Brien, T,Katusic, Z (2003) In vivo expression and function of GTP cyclohydrolase I in the rabbit carotid artery. Abstract [Details]
(2001) Recombinant endothelial nitric oxide synthase gene expression in vivo attenuates post-subarachnoid hemorrhage cerebral vasospasm. FASEB J.
Khurana GV, Smith LA, Weiler DA, Baker TA, O'Brien T, Katusic ZS (2001) Recombinant endothelial nitric oxide synthase gene expression in vivo attenuates post-subarachnoid hemorrhage cerebral vasospasm. FASEB J. Abstract [Details]
(2001) Paintbrush-assisted gene delivery. Mol Therapy.
Khurana VG, Simari RD, O'Brien T (2001) Paintbrush-assisted gene delivery. Mol Therapy. Abstract [Details]
(2001) Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in arteries without but not with atherosclerotic plaque. Mol Therapy.
Zanetti M, Sato J, Jost C, Gloviczki P, Katusic Z, O'Brien T (2001) Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in arteries without but not with atherosclerotic plaque. Mol Therapy. Abstract [Details]
(2001) Successful gene targeting to the coronary arteries or myocardium. Mol Therapy.
Branzoli S, O'Brien T, Tazelaar H, McGregor C (2001) Successful gene targeting to the coronary arteries or myocardium. Mol Therapy. Abstract [Details]
(2001) Over Expression of Bone Sialoprotein Enhances Nodule Formation and Calcification in Vascular Smooth Muscle Cells. Journal of Bone and Mineral Research, Suppl.
Harrington, SWS, O'Brien, T, Fitzpatrick, LA (2001) Over Expression of Bone Sialoprotein Enhances Nodule Formation and Calcification in Vascular Smooth Muscle Cells. Journal of Bone and Mineral Research, Suppl. Abstract [Details]
(2001) The effects of CTLA4-Ig on acute lung allograft rejection – a comparison of intrabronchial gene therapy with systemic administration of protein. Mol Therapy.
Ugurlu M, Griffin M, O'Brien T, Tazelaar H, Miller V, McGregor C (2001) The effects of CTLA4-Ig on acute lung allograft rejection – a comparison of intrabronchial gene therapy with systemic administration of protein. Mol Therapy. Abstract [Details]
(2000) Endothelial nitric oxide synthase and not superoxide dismutase gene transfer to the atherosclerotic rabbit aorta improves endothelial function. Mol Therapy.
Sato J, Katusic ZS, O'Brien T (2000) Endothelial nitric oxide synthase and not superoxide dismutase gene transfer to the atherosclerotic rabbit aorta improves endothelial function. Mol Therapy. Abstract [Details]
(2000) Improved efficiency of gene transfer to the transplanted lung by retrograde vascular gene delivery. Mol Therapy.
O'Brien T, Jeppsson A, Pellegrini C, Lee R, Miller V, Tazelaar H, McGregor C (2000) Improved efficiency of gene transfer to the transplanted lung by retrograde vascular gene delivery. Mol Therapy. Abstract [Details]
(2000) Triglyceride-rich remnant lipoproteins enhance plasminogen activator inhibitor-1 production by human aortic endothelial cells. FASEB Journal.
Sawka AM, Singh RJ, McConnell JP, Katusic ZS, O'Brien T (2000) Triglyceride-rich remnant lipoproteins enhance plasminogen activator inhibitor-1 production by human aortic endothelial cells. FASEB Journal. Abstract [Details]
(2000) Adenoviral-Mediated Gene Transfer of Catalase to Endothelial Cells Reduces Cell Proliferation via Increased Apoptosis. NAVBO.
Zanetti M, O'Brien T (2000) Adenoviral-Mediated Gene Transfer of Catalase to Endothelial Cells Reduces Cell Proliferation via Increased Apoptosis. NAVBO. Abstract [Details]
(2000) Dietary antioxidants preserve endothelium dependent vasorelaxation in obese rats. Clin Chem june 2000.
Sato J, Singh RJ, O'Brien T, Katusic ZS, Fu A, Nygren JA, Nair KS (2000) Dietary antioxidants preserve endothelium dependent vasorelaxation in obese rats. Clin Chem june 2000. Abstract [Details]
(2000) In vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits enhances endothelium-dependent relaxations. Atherosclerosis.
Sato J, Mohácsi T, Noel A, Jost C, Gloviczki P, Mozes G, Katusic Z, O'Brien T (2000) In vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits enhances endothelium-dependent relaxations. Atherosclerosis. Abstract [Details]
(2000) Adenoviral mediated gene transfer to coronary artery bypass grafts in vivo. ASGT.
Chiu C, O'Brien T, Katusic ZS, Schaff HV (2000) Adenoviral mediated gene transfer to coronary artery bypass grafts in vivo. ASGT. Abstract [Details]
(2000) Low concentrations of remnant lipoproteins increase plasminogen activator inhibitor-1 secretion by human aortic endothelial cells. Diabetes.
Sawka A, Singh RJ, Hiddinga HJ, McConnell JP, Eberhardt NL, Caplice NM, O'Brien T (2000) Low concentrations of remnant lipoproteins increase plasminogen activator inhibitor-1 secretion by human aortic endothelial cells. Diabetes. Abstract [Details]
(2000) Gene transfer to saphenous vein coronary bypass conduits. FASEB J.
Chiu C, O'Brien T, Katusic ZS, Cable DG, Schaff HV (2000) Gene transfer to saphenous vein coronary bypass conduits. FASEB J. Abstract [Details]
(2000) Gene transfer to saphenous vein coronary bypass conduits. Mol Therapy.
Chiu C, O'Brien T, Katusic ZS, Schaff HV (2000) Gene transfer to saphenous vein coronary bypass conduits. Mol Therapy. Abstract [Details]
(2000) Gene transfer of manganese and copper/zinc superoxide dismutase improves vascular dysfunction in diabetic aorta. Diabetes.
Zanetti M, Sato J, Katusic ZS, O'Brien T (2000) Gene transfer of manganese and copper/zinc superoxide dismutase improves vascular dysfunction in diabetic aorta. Diabetes. Abstract [Details]
(2000) Gene transfer approaches to limiting vascular dysfunction in experimental diabetes mellitus: endothelial Nitric Oxide Synthase vs superoxide dismutase. Juvenile Diabetes Foundation.
O'Brien T, Zanetti M, Katusic ZS (2000) Gene transfer approaches to limiting vascular dysfunction in experimental diabetes mellitus: endothelial Nitric Oxide Synthase vs superoxide dismutase. Juvenile Diabetes Foundation. Abstract [Details]
(1999) Infection of adrenal zona glomerulosa cells with endothelial-nitric oxide synthase adenovirus: inhibition of aldosterone synthesis by endogenous nitric oxide. Council for High Blood Pressure Research.
Hanke CJ, Pritchard KA Jr, O'Brien T, Campbell WB (1999) Infection of adrenal zona glomerulosa cells with endothelial-nitric oxide synthase adenovirus: inhibition of aldosterone synthesis by endogenous nitric oxide. Council for High Blood Pressure Research. Abstract [Details]
(1999) Manganese superoxide dismutase gene transfer and glucose-mediated inhibition of endothelial cell migration. Diabetes.
Sato J, Chiu CK, Zanetti M, O'Brien T (1999) Manganese superoxide dismutase gene transfer and glucose-mediated inhibition of endothelial cell migration. Diabetes. Abstract [Details]
(1999) Effects of in vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits. American Society of Gene Therapy 2nd Annual Meeting.
Sato J, Mohasci T, Noel AA, Gloviczki P, Mozes GI, Katusic ZS, O'Brien T (1999) Effects of in vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits. American Society of Gene Therapy 2nd Annual Meeting. Abstract [Details]
(1999) Surgical treatment of valvular heart disease in patients with acromegaly. World Congress on Heart Valve Disease, London UK.
Cable DG, Dearani JA, O'Brien T, Orszulak TA, Puga FJ, Schaff HV (1999) Surgical treatment of valvular heart disease in patients with acromegaly. World Congress on Heart Valve Disease, London UK. Abstract [Details]
(1999) Surgical Treatment of Valvular Heart Disease in Patients with Acromegaly and Cardiomyopathy. J Am Coll Cardio.
Cable DG, Dearani JA, O'Brien T, Orszulak TA, Puga FJ, Schaff HV (1999) Surgical Treatment of Valvular Heart Disease in Patients with Acromegaly and Cardiomyopathy. J Am Coll Cardio. Abstract [Details]
(1999) Gene transfer of endothelial nitric oxide synthase and manganese superoxide dismutase improves vascular reactivity of aortas from diabetic rabbits. Circulation.
Zanetti M, Sato J, Katusic ZS, O'Brien T (1999) Gene transfer of endothelial nitric oxide synthase and manganese superoxide dismutase improves vascular reactivity of aortas from diabetic rabbits. Circulation. Abstract [Details]
(1999) Transfer of the endothelial nitric oxide synthase gene to coronary smooth muscle cells inhibits cell proliferation via up-regulation of p27 and p21 and not apoptosis. Circulation.
Sato J, Nair K, Hiddinga J, Eberhardt NL, Fitzpatrick LA, Katusic ZS, O'Brien T (1999) Transfer of the endothelial nitric oxide synthase gene to coronary smooth muscle cells inhibits cell proliferation via up-regulation of p27 and p21 and not apoptosis. Circulation. Abstract [Details]
(1999) Transfer of the endothelial nitric oxide synthase gene to human umbilical vein endothelial cells inhibits cell proliferation. American Society of Gene Therapy 2nd Annual Meeting.
Zanetti M, Katusic ZS, O'Brien T (1999) Transfer of the endothelial nitric oxide synthase gene to human umbilical vein endothelial cells inhibits cell proliferation. American Society of Gene Therapy 2nd Annual Meeting. Abstract [Details]
(1999) Endothelial nitric oxide synthase gene transfer to the vasculature. Gene Therapy.
O'Brien T, Sato J, Kullo I, Mozes G, Gloviczki P, Katusic Z (1999) Endothelial nitric oxide synthase gene transfer to the vasculature. Gene Therapy. Abstract [Details]
(1999) Adenoviral-mediated catalase gene transfer to endothelial cells reduces cell proliferation. Circulation.
Zanetti M, O'Brien T (1999) Adenoviral-mediated catalase gene transfer to endothelial cells reduces cell proliferation. Circulation. Abstract [Details]
(1999) Copper zinc superoxide dismutase gene transfer to endothelial cells reduces glucose-mediated cytotoxicity. Diabetes.
Zanetti M, O'Brien T (1999) Copper zinc superoxide dismutase gene transfer to endothelial cells reduces glucose-mediated cytotoxicity. Diabetes. Abstract [Details]
(1999) Endothelial nitric oxide synthase gene transfer to the vasculature. Cytoreductive Gene Therapy, Rochester MN.
O'Brien T, Sato J, Kullo I, Mozes G, Gloviczki P, Katusic Z (1999) Endothelial nitric oxide synthase gene transfer to the vasculature. Cytoreductive Gene Therapy, Rochester MN. Abstract [Details]
(1999) Cyclosporin A and glucocorticoids inhibit osteoprotegerin production in human osteoblastic and coronary artery smooth muscle cells: potential mechanism of post-transplant osteoporosis and vascular disease. ASBMR, J Bone Miner.
Hofbauer LC, Riggs BL, Dunstan CR, O'Brien T, Khosla S (1999) Cyclosporin A and glucocorticoids inhibit osteoprotegerin production in human osteoblastic and coronary artery smooth muscle cells: potential mechanism of post-transplant osteoporosis and vascular disease. ASBMR, J Bone Miner. Abstract [Details]
(1999) Highly efficient gene transfer to the transplanted heart by circulation of a low dose of adenoviral vector. American Society of Gene Therapy 2nd Annual Meeting.
Pellegrini C, Taner CB, Jeppsson A, O'Brien T, Miller VM, Tazelaar HD, McGregor CGA (1999) Highly efficient gene transfer to the transplanted heart by circulation of a low dose of adenoviral vector. American Society of Gene Therapy 2nd Annual Meeting. Abstract [Details]
(1999) Gene transfer of endothelial nitric oxide synthase to transplanted lungs. Acta Physiol Scan.
Jeppsson A, Pellegrini C, O'Brien T, Miller VM, Tazelaar HD, Taner CB, McGregor CGA (1999) Gene transfer of endothelial nitric oxide synthase to transplanted lungs. Acta Physiol Scan. Abstract [Details]
(1999) Effects of eNOS gene transfer on vascular reactivity of alloxan-induced diabetic rabbit aorta. Diabetes.
Zanetti M, Sato J, Katusic ZS, O'Brien T (1999) Effects of eNOS gene transfer on vascular reactivity of alloxan-induced diabetic rabbit aorta. Diabetes. Abstract [Details]
(1999) Transfer of the endothelial nitric oxide synthase gene to human umbilical vein endothelial cells inhibits cell proliferation. FASEB Experimental Biology, Washington DC, April 1999.
Zanetti M, Sato J, Katusic ZS, O'Brien T (1999) Transfer of the endothelial nitric oxide synthase gene to human umbilical vein endothelial cells inhibits cell proliferation. FASEB Experimental Biology, Washington DC, April 1999. Abstract [Details]
(1999) Obesity-associated vascular dysfunction is prevented by antioxidant treatment. Circulation.
O'Brien T, Sato J, Fu A, Nygren J, Katusic Z, Nair KS (1999) Obesity-associated vascular dysfunction is prevented by antioxidant treatment. Circulation. Abstract [Details]
(1998) Gene transfer in lung transplantation. The FASEB Journal.
Taner CB, Jeppsson A, Pellegrini C, Miller VM, O'Brien T, Tazelaar HD, McGregor CGA (1998) Gene transfer in lung transplantation. The FASEB Journal. Abstract [Details]
(1998) Adenovirus-mediated gene transfer to the transplanted heart results predominantly in cardiomyocyte transgene expression. American Society of Gene Therapy, 1st Annual Meeting.
Pellegrini C, O'Brien T, Yap J, Taner CB, Jeppsson A, Miller VM, Tazelaar HD, McGregor CGA (1998) Adenovirus-mediated gene transfer to the transplanted heart results predominantly in cardiomyocyte transgene expression. American Society of Gene Therapy, 1st Annual Meeting. Seattle, WA: Abstract [Details]
(1998) Sclerosing lymphocytic lobulitis: A breast disorder specific for type 1 diabetes mellitus. Endocrine Society, 80th Annual Meeting, June 24-27, 1998, New Orleans Abstracts:.
Kudva YC, O'Brien T, Crotty TB (1998) Sclerosing lymphocytic lobulitis: A breast disorder specific for type 1 diabetes mellitus. Endocrine Society, 80th Annual Meeting, June 24-27, 1998, New Orleans Abstracts:. Abstract [Details]
(1998) Adenoviral-receptor mediated gene transfer to human cerebral arrtery. Vascular and Myocardial Aspects of Ischemic Heart Disease, Lake Tahoe.
Chen AFY, Mertens LL, Parisi JE, O'Brien T, Katusic ZS (1998) Adenoviral-receptor mediated gene transfer to human cerebral arrtery. Vascular and Myocardial Aspects of Ischemic Heart Disease, Lake Tahoe. Abstract [Details]
(1998) Adenoviral mediated transbronchial gene transfer of endothelial nitric oxide synthase to transplanted lungs. Society of Thoracic surgery.
Jeppsson A, Pellegrini C, O'Brien T, Miller VM, Tazelaar HD, McGregor C (1998) Adenoviral mediated transbronchial gene transfer of endothelial nitric oxide synthase to transplanted lungs. Society of Thoracic surgery. New Orleans: Abstract [Details]
(1998) Gene transfer in lung transplantation: Retrograde gene delivery via the pulmonary vein improves transduction efficiency. The International Society for Heart and Lung Transplantation, Chicago Illinois The Journal of Heart and Lung Transplantation.
Jeppsson A, Pellegrini C, O'Brien T, Miller VM, Tazelaar HD, McGregor C (1998) Gene transfer in lung transplantation: Retrograde gene delivery via the pulmonary vein improves transduction efficiency. The International Society for Heart and Lung Transplantation, Chicago Illinois The Journal of Heart and Lung Transplantation. Abstract [Details]
(1998) In vivo assessment of endothelial nitric oxide synthase transduced to transplanted lungs. FASEB Journal.
Severson SR, Jeppsson A, O'Brien T, Pellegrini C, Miller VM, Tazelaar HD, McGregor CGA (1998) In vivo assessment of endothelial nitric oxide synthase transduced to transplanted lungs. FASEB Journal. Abstract [Details]
(1998) Is adenoviral-mediated gene transfer to transplanted hearts enhanced by University of Wisconsin solution?. American Society of Gene Therapy, 1st Annual Meeting.
Pellegrini C, O'Brien T, Taner CB, Miller VM, Tazelaar HD, McGregor CGA (1998) Is adenoviral-mediated gene transfer to transplanted hearts enhanced by University of Wisconsin solution?. American Society of Gene Therapy, 1st Annual Meeting. Seattle, WA: Abstract [Details]
(1998) Recombinant eNOS gene expression and cerebral arterial reactivity to endothelin-1 - implications for gene therapy of chronic cerebral vasospasm. American Society of Gene Therapy, 1st Annual Meeting.
Onoue H, Tsutsui M, Smith L, O'Brien T, Katusic ZS (1998) Recombinant eNOS gene expression and cerebral arterial reactivity to endothelin-1 - implications for gene therapy of chronic cerebral vasospasm. American Society of Gene Therapy, 1st Annual Meeting. Seattle, WA: Abstract [Details]
(1998) UVB-induced H-20-2 activitates ERK1/2 but no P38 pathway via EGFR phosphorylation: Effects on keratinocyte growth and survival. Journal of Investigative Dermatology.
Pittelkow MR, Vasa R, Meves A, Beyerle A, O'Brien T, Peus, D (1998) UVB-induced H-20-2 activitates ERK1/2 but no P38 pathway via EGFR phosphorylation: Effects on keratinocyte growth and survival. Journal of Investigative Dermatology. Abstract [Details]
(1998) Angiotensin II causes relaxations of canine cerebral arteries transduced with recombinant endothelial nitric oxide synthase gene. CirculationAmerican Heart Association.
Tsutsui M, Iida Y, Onoue H, Smith L, O'Brien T, Katusic ZS (1998) Angiotensin II causes relaxations of canine cerebral arteries transduced with recombinant endothelial nitric oxide synthase gene. CirculationAmerican Heart Association. Dallas, Texas: Abstract [Details]
(1998) Expression of recombinant endothelial nitric oxide synthase gene reverses contractile effect of serum into relaxations. CirculationAmerican Heart Association.
Tsutsui M, Iida Y, Onoue H, Smith L, O'Brien T, Katusic ZS (1998) Expression of recombinant endothelial nitric oxide synthase gene reverses contractile effect of serum into relaxations. CirculationAmerican Heart Association. Dallas, Texas: Abstract [Details]
(1998) The role of gene therapy for intimal hyperplasia of bypass grafts. CirculationAmerican Heart Association.
Cable DG, Caccitolo JA, Caplice N, O'Brien T, Simari RD, Daly RC, Dearani JA, Mullany CJ, Orszulak TA, Schaff HV (1998) The role of gene therapy for intimal hyperplasia of bypass grafts. CirculationAmerican Heart Association. Dallas, Texas: Abstract [Details]
(1998) Gene transfer of endothelial nitric oxide synthase to acute rejecting pulmonary allografts. Third International Congress on Lung Transplantation.
Jeppsson A, Pellegrini C, O'Brien T, Miller VM, Tazelaar HD, Taner CB, McGregor CGA (1998) Gene transfer of endothelial nitric oxide synthase to acute rejecting pulmonary allografts. Third International Congress on Lung Transplantation. Paris: Abstract [Details]
(1998) Adenoviral receptor-mediated gene transfer to human cerebral artery. XIIth International Congress of Pharmacology, Munchen, Germany.
Chen FY, Mertens LL, Parisi JE, O'Brien T, Katusic ZS (1998) Adenoviral receptor-mediated gene transfer to human cerebral artery. XIIth International Congress of Pharmacology, Munchen, Germany. Abstract [Details]
(1998) The role of eNOS gene therapy to augment coronary relaxations during hypoxia. Circulation American Heart Association.
Cable DG, Pompili VJ, O'Brien T, Schaff HV (1998) The role of eNOS gene therapy to augment coronary relaxations during hypoxia. Circulation American Heart Association. Dallas, Texas: Abstract [Details]
(1998) UVB-induced H, 20, 2 activates ERK1/2 but not p38 pathway via EGFR phosphorylation: Effects on keratinocyte growth and survival. J Derm Science.
Pittelkow MR, Vasa R, Meves A, Beyerle A, O'Brien T, Peus D (1998) UVB-induced H, 20, 2 activates ERK1/2 but not p38 pathway via EGFR phosphorylation: Effects on keratinocyte growth and survival. J Derm Science. Abstract [Details]
(1998) Absence of toxicity associated with adenoviral-mediated gene transfer to the islets of Langerhans. American Society of Gene Therapy, 1st Annual Meeting.
O'Brien T, Karlsen AE, Andersen HU, Mandrup-Poulsen T, Nerup J (1998) Absence of toxicity associated with adenoviral-mediated gene transfer to the islets of Langerhans. American Society of Gene Therapy, 1st Annual Meeting. Seattle, WA: Abstract [Details]
(1998) CGA:Transgene expression in cardiac allografts is not prolonged by high circulating levels of cyclosporine. European Association for Cardio-Thoracic Surgery.
Pellegrini C, Jeppsson A, O'Brien T, Miller VM, Tazelaar HD, McGregor (1998) CGA:Transgene expression in cardiac allografts is not prolonged by high circulating levels of cyclosporine. European Association for Cardio-Thoracic Surgery. Abstract [Details]
(1998) Gene transfer in lung transplantation: Vascular gene delivery. Scandanavian Association of Thoracic Surgery.
Jeppsson A, Pellegrini C, O'Brien T, Miller VM, Tazelaar HD, Taner CB, McGregor C (1998) Gene transfer in lung transplantation: Vascular gene delivery. Scandanavian Association of Thoracic Surgery. Abstract [Details]
(1998) Adenoviral-mediated gene transfer of eNOS to canine gastroepiploic arteries: a technique to limit vasospasm. FASEB Journal.
Cable DG, Caccitolo JA, O'Brien T, Schaff HV (1998) Adenoviral-mediated gene transfer of eNOS to canine gastroepiploic arteries: a technique to limit vasospasm. FASEB Journal. Abstract [Details]
(1998) Adventitial expression of recombinant endothelial nitric oxide synthase gene reverses vasoconstrictor effect of endothelin-1. FASEB Journal.
Onoue H, Tsutsui M, Smith L, O'Brien T, Katusic ZS (1998) Adventitial expression of recombinant endothelial nitric oxide synthase gene reverses vasoconstrictor effect of endothelin-1. FASEB Journal. Abstract [Details]
(1998) Transfer of the endothelial nitric oxide synthase gene to coronary smooth muscle cells blocks cell cycle progression in G1. CirculationAmerican Heart Association.
Sato J, Fitzpatrick LA, Katusic ZS, O'Brien T (1998) Transfer of the endothelial nitric oxide synthase gene to coronary smooth muscle cells blocks cell cycle progression in G1. CirculationAmerican Heart Association. Dallas, Texas: Abstract [Details]
(1998) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. Vascular and Myocardial Aspects of Ischemic Heart Disease.
O'Brien T, Mozes G, Kullo I, Gloviczki P, Katusic Z (1998) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. Vascular and Myocardial Aspects of Ischemic Heart Disease. Lake Tahoe: Abstract [Details]
(1998) Gene transfer to human cerebral artery. FASEB Journal.
Chen AFY, Mertens LL, Jiang S, Parisi JE, O'Brien T, Katusic ZS (1998) Gene transfer to human cerebral artery. FASEB Journal. Abstract [Details]
(1998) Adenoviral-mediated gene transfer to adipose tissue. American Society of Gene Therapy, 1st Annual Meeting.
Levine J, Eberhardt N, Jensen M, O'Brien T (1998) Adenoviral-mediated gene transfer to adipose tissue. American Society of Gene Therapy, 1st Annual Meeting. Seattle, WA: Abstract [Details]
(1997) Adventitial expression of recombinant endothelial nitric oxide synthase gene restores nitric oxide production in cerebral arteries without endothelium. Journal of Cerebral Blood Flow and Metabolism.
Tsutsui M, Chen AF, O'Brien T, Crotty TB, Katusic ZS (1997) Adventitial expression of recombinant endothelial nitric oxide synthase gene restores nitric oxide production in cerebral arteries without endothelium. Journal of Cerebral Blood Flow and Metabolism. Abstract [Details]
(1997) Adventitial expression of recombinant endothelial nitric oxide synthase gene restores nitric oxide production in arteries without endothelium. American Heart Association, Orlando, Florida Circulation.
Tsutsui M, Chen AF, O'Brien T, Crotty TB, Katusic ZS (1997) Adventitial expression of recombinant endothelial nitric oxide synthase gene restores nitric oxide production in arteries without endothelium. American Heart Association, Orlando, Florida Circulation. Abstract [Details]
(1997) Absence of toxicity with adenoviral mediated gene transfer to the islets of Langerhans. International Diabetes Federation, Helsinki Finland Late Breaking Research Session.
O'Brien T, Karlsen AE, Anderson HU, Mandrup-Poulsen T, Nerup J (1997) Absence of toxicity with adenoviral mediated gene transfer to the islets of Langerhans. International Diabetes Federation, Helsinki Finland Late Breaking Research Session. Abstract [Details]
(1997) Heterogeneity of adenovirus-mediated transfer of endothelial nitric oxide synthase gene in isolated canine arteries. FASEB J.
Tsutsui M, Chen AFY, O'Brien T, Crotty TB, Katusic ZS (1997) Heterogeneity of adenovirus-mediated transfer of endothelial nitric oxide synthase gene in isolated canine arteries. FASEB J. Abstract [Details]
(1997) In vivo eNOS gene transfer in cerebral arteries via cerebrospinal fluid. FASEB J.
Chen AFY, Smith LA, Crotty TB, O'Brien T, Katusic ZS (1997) In vivo eNOS gene transfer in cerebral arteries via cerebrospinal fluid. FASEB J. Abstract [Details]
(1997) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. International Atherosclerosis Symposium, Paris, France Atherosclerosis.
O'Brien T, Mozes G, Kullo IK, Cable D, Crotty T, Gloviczki P, Katusic Z (1997) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. International Atherosclerosis Symposium, Paris, France Atherosclerosis. Abstract [Details]
(1997) Tetrahydrobiopterin increases activity of recombinant endothelial nitric oxide synthase. FASEB J.
Kullo IJ, Schwartz RS, Tsutsui M, Milstein S, Katusic ZS, O'Brien T (1997) Tetrahydrobiopterin increases activity of recombinant endothelial nitric oxide synthase. FASEB J. Abstract [Details]
(1997) Immunosuppression prolongs adenoviral mediated transgene expression in cardiac allograft transplantation. Molecular and Cellular Biology of Gene Therapy.
O'Brien T, Yap J, Tazelaar HD, McGregor CGA (1997) Immunosuppression prolongs adenoviral mediated transgene expression in cardiac allograft transplantation. Molecular and Cellular Biology of Gene Therapy. utah: Abstract [Details]
(1997) Adenoviral mediated gene transfer of macrophage colony stimulating factor to the vessel wall results in an intimal infiltrate. European Atherosclerosis Society, Brugges 1997 Atherosclerosis.
Mozes G, Kullo I, Mohasci T, Gloviczki P, O'Brien T (1997) Adenoviral mediated gene transfer of macrophage colony stimulating factor to the vessel wall results in an intimal infiltrate. European Atherosclerosis Society, Brugges 1997 Atherosclerosis. Abstract [Details]
(1997) In vivo expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries. 7th Symposium on Mechanisms of Vasodilatation, Maastricht, The netherlands J Vasc Res 3.
Chen AFY, Smith LA, Tsutsui M, Crotty TB, O'Brien T, Katusic ZS (1997) In vivo expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries. 7th Symposium on Mechanisms of Vasodilatation, Maastricht, The netherlands J Vasc Res 3. Abstract [Details]
(1997) Immunosuppression prolongs adenoviral mediated transgene expression in cardiac allograft transplantation. International Society for Heart and Lung Transplantation, London UK J Heart and Lung Transplantation.
Yap J, O'Brien T, Tazelaar HD, McGregor CGA (1997) Immunosuppression prolongs adenoviral mediated transgene expression in cardiac allograft transplantation. International Society for Heart and Lung Transplantation, London UK J Heart and Lung Transplantation. Abstract [Details]
(1997) Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries. American College of Physicians, Philadelphia.
Kullo IJ, Mozes G, Schwartz RS, Gloviczki P, Crotty TB, Katusic ZS, O'Brien T (1997) Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries. American College of Physicians, Philadelphia. Abstract [Details]
(1997) New approaches to prevention and treatment of vasospasm of radial artery bypass grafts. American Heart Association, Orlando, Florida Circulation.
Cable DG, Caccitolo JA, pearson PJ, O'Brien T, Mullany CJ, daly RC, Orszulak TA, Schaff HV (1997) New approaches to prevention and treatment of vasospasm of radial artery bypass grafts. American Heart Association, Orlando, Florida Circulation. Abstract [Details]
(1997) Adventitial gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries alters vascular reactivity. JACC.
Kullo IJ, Mozes G, Schwartz RS, Gloviczki P, Crotty TB, Katusic ZS, O'Brien T (1997) Adventitial gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries alters vascular reactivity. JACC. Abstract [Details]
(1997) Adenoviral mediated ex vivo gene transfer to the transplanted heart. Society of Cardiothoracic Surgeons of Great Britain and Ireland, Dublin.
Yap J, O'Brien T, Tazelaar HD, McGregor CGA (1997) Adenoviral mediated ex vivo gene transfer to the transplanted heart. Society of Cardiothoracic Surgeons of Great Britain and Ireland, Dublin. Abstract [Details]
(1997) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. Molecular and Cellular Biology of Gene Therapy.
Kullo, Mozes G, Cable D, Crotty T, Gloviczki P, Katusic Z, O'Brien T (1997) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. Molecular and Cellular Biology of Gene Therapy. utah: Abstract [Details]
(1997) Adenoviral mediated gene transfer of eNOS to canine coronary arteries augments hypoxic induced relaxations. Molecular and Cellular Biology of Gene Therapy.
Cable DG, O'Brien T, Pompili VJ, Schaff HV (1997) Adenoviral mediated gene transfer of eNOS to canine coronary arteries augments hypoxic induced relaxations. Molecular and Cellular Biology of Gene Therapy. utah: Abstract [Details]
(1997) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. Biomedicine J Investigative Medicine 1997.
Kullo, Mozes G, Cable D, Crotty T, Gloviczki P, Katusic Z, O'Brien T (1997) Nitric oxide synthase gene transfer improves cholesterol-induced vasomotor dysfunction in the rabbit aorta. Biomedicine J Investigative Medicine 1997. Abstract [Details]
(1997) Vascular adenoviral mediated gene transfer of endothelial nitric oxide synthase to the chow and cholesterol fed rabbit alters vascular reactivity. European Atherosclerosis Society, Brugges 1997 Atherosclerosis.
Kullo I, Mozes G, Schwartz RS, Gloviczki P, Crotty TB, Katusic ZS, O'Brien T (1997) Vascular adenoviral mediated gene transfer of endothelial nitric oxide synthase to the chow and cholesterol fed rabbit alters vascular reactivity. European Atherosclerosis Society, Brugges 1997 Atherosclerosis. Abstract [Details]
(1997) Diabetic mastopathy: a clinicopathologic study. American Diabetes Association Boston Diabetes.
Kudva YC, O'Brien T, Crotty TB (1997) Diabetic mastopathy: a clinicopathologic study. American Diabetes Association Boston Diabetes. Abstract [Details]
(1997) In vivo adenoviral mediated expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries. Brain, Journal of Cerebral Blood Flow and Metabolism.
Chen AFY, Smith LA, Crotty TB, O'Brien T, Katusic ZS (1997) In vivo adenoviral mediated expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries. Brain, Journal of Cerebral Blood Flow and Metabolism. Abstract [Details]
(1997) Effect of in vivo recombinant adenoviral-mediated gene transfer on vascular reactivity of canine cerebral arteries. Stroke.
Chen AFY, Smith LA, Crotty TB, O'Brien T, Katusic ZS (1997) Effect of in vivo recombinant adenoviral-mediated gene transfer on vascular reactivity of canine cerebral arteries. Stroke. Abstract [Details]
(1997) Adenoviral transduction in the transplanted rat lung. International Society for Heart and Lung Transplantation, London, UK.
Lee RJ, O'Brien T, Tazelaar HD, McGregor CGA (1997) Adenoviral transduction in the transplanted rat lung. International Society for Heart and Lung Transplantation, London, UK. Abstract [Details]
(1997) Vasospasm of radial artery bypass grafts: Studies of endothelial regulation of vascular smooth muscle function and manipulation by gene therapy. Western Surgical Society.
Cable D, O'Brien T, Schaff HV (1997) Vasospasm of radial artery bypass grafts: Studies of endothelial regulation of vascular smooth muscle function and manipulation by gene therapy. Western Surgical Society. Abstract [Details]
(1997) Adventital fibroblasts as target cells for expression of recombinant endothelial nitric oxide synthase gene. Jap J Pharmacol.
Katusic ZS, Chen AFY, O'Brien T, Crotty TB (1997) Adventital fibroblasts as target cells for expression of recombinant endothelial nitric oxide synthase gene. Jap J Pharmacol. Abstract [Details]
(1996) Recombinant eNOS transduced saphenous veins: Gene therapy in bypass conduits. IX International Vascular Biology Meeting.
Cable DG, O'Brien T, Schaff HV, Pompili VJ (1996) Recombinant eNOS transduced saphenous veins: Gene therapy in bypass conduits. IX International Vascular Biology Meeting. Seattle, Washington: Abstract [Details]
(1996) Normal vasomotor function after ex vivo recombinant adenoviral vector-mediated gene transfer and expression in canine basilar artery. 21st International Joint Conference on Stroke and Cerebral Circulation.
Chen AF, O'Brien T, Crotty TB, Katusic ZS (1996) Normal vasomotor function after ex vivo recombinant adenoviral vector-mediated gene transfer and expression in canine basilar artery. 21st International Joint Conference on Stroke and Cerebral Circulation. Abstract [Details]
(1996) Optimization of gene transfer to the transplanted heart. American Heart Association, New Orleans Circulation.
Yap JYM, O'Brien T, Tazelaar HD, McGregor CGA (1996) Optimization of gene transfer to the transplanted heart. American Heart Association, New Orleans Circulation. Abstract [Details]
(1996) Adenoviral-mediated gene transfer of monocyte chemotactic protein-1 (MCP-1) to the arterial wall. IX International Vascular Biology Meeting, Seattle, Washington J Vasc Res.
Kullo IJ, Serry R, Menawat S, Mozes G, Gloviczki P, Taylor J, O'Brien T (1996) Adenoviral-mediated gene transfer of monocyte chemotactic protein-1 (MCP-1) to the arterial wall. IX International Vascular Biology Meeting, Seattle, Washington J Vasc Res. Abstract [Details]
(1996) Adenoviral-mediated gene transfer of nitric oxide synthase (NOS) to the vascular wall yields functional enzymatic activity. Diabetes, Lipoproteins and Atherosclerosis: EASD Lipoprotein Study Group.
O'Brien T, Kullo I, Chen A, Katusic Z (1996) Adenoviral-mediated gene transfer of nitric oxide synthase (NOS) to the vascular wall yields functional enzymatic activity. Diabetes, Lipoproteins and Atherosclerosis: EASD Lipoprotein Study Group. Dublin: Abstract [Details]
(1996) Effect of recombinant endothelial nitric oxide synthase gene expression on reactivity of isolated canine basilar artery. FASEB.
Chen AFY, Kinoshita H, Tsutsui M, O'Brien T, Pompili VJ, Crotty T, Katusic ZS (1996) Effect of recombinant endothelial nitric oxide synthase gene expression on reactivity of isolated canine basilar artery. FASEB. Abstract [Details]
(1996) Endothelial nitric oxide synthase gene transfer to porcine coronary smooth muscle cells inhibits cell proliferation. Restenosis Summit VIII.
Kullo I, Schwartz RS, Tsutsui M, Katusic ZS, Pompili VJ, O'Brien T (1996) Endothelial nitric oxide synthase gene transfer to porcine coronary smooth muscle cells inhibits cell proliferation. Restenosis Summit VIII. Cleveland, OH: Abstract [Details]
(1996) Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery. International Angiology.
Chen AFY, Tsutsui M, Kinoshita H, O'Brien T, Crotty TB, Pompili VJ, Katusic ZS (1996) Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery. International Angiology. Abstract [Details]
(1996) Transfer of endothelial nitric oxide synthase gene to coronary smooth muscle cells inhibits cell proliferation. American Heart Association, New Orleans Circulation.
Kullo IJ, Pompili VJ, Tsutsui M, Fitzpatrick LA, Katusic ZS, O'Brien T (1996) Transfer of endothelial nitric oxide synthase gene to coronary smooth muscle cells inhibits cell proliferation. American Heart Association, New Orleans Circulation. Abstract [Details]
(1996) Adenoviral transfection of human saphenous veins with e NOS: Gene therapy applied to coronary bypass conduits. American Heart Association, New Orleans Circulation.
Cable DG, O'Brien T, Schaff HV, Katusic ZS, Pompili VJ (1996) Adenoviral transfection of human saphenous veins with e NOS: Gene therapy applied to coronary bypass conduits. American Heart Association, New Orleans Circulation. Abstract [Details]
(1996) Adenoviral transduction of endothelial cell nitric oxide synthase gene yielding functional enzymatic activity in porcine coronary arteries. American College of Cardiology JACC.
Pompili VJ, O'Brien T, Kullo I, Spector D, Schwartz RS, Holmes DR, Katusic ZS (1996) Adenoviral transduction of endothelial cell nitric oxide synthase gene yielding functional enzymatic activity in porcine coronary arteries. American College of Cardiology JACC. Abstract [Details]
(1996) Adenoviral mediated gene transfer of nitric oxide synthase (NOS) to the vascular wall yields functional enzymatic activity. European Atherosclerosis Society Florence.
O'Brien T, Kullo I, Chen A, Katusic Z (1996) Adenoviral mediated gene transfer of nitric oxide synthase (NOS) to the vascular wall yields functional enzymatic activity. European Atherosclerosis Society Florence. Abstract [Details]
(1996) Adenoviral-mediated transfer of recombinant endothelial nitric oxide synthase gene in canine basilar artery. Joint Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Salt Lake City, UT.
Chen AFY, Tsutsui M, Kinoshita H, O'Brien T, Pompili VJ, Katusic ZS (1996) Adenoviral-mediated transfer of recombinant endothelial nitric oxide synthase gene in canine basilar artery. Joint Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Salt Lake City, UT. Abstract [Details]
(1996) Effect of recombinant endothelial nitric oxide synthase gene expression on endothelium dependent relaxations in canine arteries. IX International Vascular Biology Meeting, Seattle, Washington.
Katusic ZS, Tsutsui M, Chen AFY, O'Brien T, Crotty TB (1996) Effect of recombinant endothelial nitric oxide synthase gene expression on endothelium dependent relaxations in canine arteries. IX International Vascular Biology Meeting, Seattle, Washington. Abstract [Details]
(1996) Effects of overexpression of type III nitric oxide synthase gene in rabbit carotid arteries in vivo. American Heart Association, New Orleans Circulation.
Kullo IJ, Mozes G, Tsutsui M, Gloviczki P, Schwartz RS, Katusic ZS, O'Brien T (1996) Effects of overexpression of type III nitric oxide synthase gene in rabbit carotid arteries in vivo. American Heart Association, New Orleans Circulation. Abstract [Details]
(1995) Adenoviral-mediated delivery and expression of the endothelial nitric oxide synthase gene in isolated porcine coronary arteries and cultured smooth muscle cells. Gene Therapy for Acquired Diseases, Nashville, TN.
Kullo IJ, O'Brien T, Katusic ZS, Pompili VJ (1995) Adenoviral-mediated delivery and expression of the endothelial nitric oxide synthase gene in isolated porcine coronary arteries and cultured smooth muscle cells. Gene Therapy for Acquired Diseases, Nashville, TN. Abstract [Details]
(1995) Endocrine and extraendocrine features of multiple endocrine neoplasia type 2B. British Journal of Surgery.
O'Riordain DS, O'Brien T, Gharib H, Grant CS, van Heerden JA (1995) Endocrine and extraendocrine features of multiple endocrine neoplasia type 2B. British Journal of Surgery. Abstract [Details]
(1993) Subtotal pancreatectomy for insulinoma in multiple endocrine neoplasia type 1. International Surgery Week Hong Kong.
O'Riordan DS, O'Brien T, van Heerden JA, Service FJ, Weaver A, Grant CS (1993) Subtotal pancreatectomy for insulinoma in multiple endocrine neoplasia type 1. International Surgery Week Hong Kong. Abstract [Details]
(1993) Surgical management of hyperparathyroidism in multiple endocrine neoplasia. American Association of Endocrine Surgeons.
O'Riordan DS, O'Brien T, Grant CS, Gharib H, Weaver A, van Heerden JA (1993) Surgical management of hyperparathyroidism in multiple endocrine neoplasia. American Association of Endocrine Surgeons. Abstract [Details]
(1993) Insulin Surrogates in Insulinoma. Endocrine Society, Las Vegas.
O'Brien T, O'Brien P, Service FJ (1993) Insulin Surrogates in Insulinoma. Endocrine Society, Las Vegas. Abstract [Details]
(1993) A high-carbohydrate diet and lipoprotein composition in NIDDM. Irish Endocrine Society, Dublin, Ireland Irish J Med Sci.
O'Brien T, Nguyen TT, Kottke BA (1993) A high-carbohydrate diet and lipoprotein composition in NIDDM. Irish Endocrine Society, Dublin, Ireland Irish J Med Sci. Abstract [Details]
(1993) The effect of a high carbohydrate diet on postprandial transfer of apolipoproteins between triglyceride rich and high density lipoproteins. European Atherosclerosis Society Jerusalem, Isreal.
O'Brien T, Nguyen TT, Kottke BA (1993) The effect of a high carbohydrate diet on postprandial transfer of apolipoproteins between triglyceride rich and high density lipoproteins. European Atherosclerosis Society Jerusalem, Isreal. Abstract [Details]
(1993) Adenoviral mediated gene transfer of apo E to the rabbit carotid artery in vivo. European Atherosclerosis Society.
O'Brien T, Quan R, Sanan D, Spector D, Taylor J (1993) Adenoviral mediated gene transfer of apo E to the rabbit carotid artery in vivo. European Atherosclerosis Society. Abstract [Details]
(1993) HDL subparticles and coronary artery disease. American Heart Association Circulation.
O'Brien T, Nguyen TT, Hallaway BJ, Kottke BA (1993) HDL subparticles and coronary artery disease. American Heart Association Circulation. Abstract [Details]
(1993) A high carbohydrate diet and high density lipoprotein subparticles in non-insulin dependent diabetes mellitus. American Diabetes Association.
O'Brien T, Nguyen TT, Kottke BA (1993) A high carbohydrate diet and high density lipoprotein subparticles in non-insulin dependent diabetes mellitus. American Diabetes Association. Abstract [Details]
(1992) How best to feed a patient with an immune paraneoplastic gut dysmotility syndrome. American Society of Parenteral and Enteral Nutrition.
O'Brien T, Mc Mahon M, Mishark K, Lennon VA, Camilleri M (1992) How best to feed a patient with an immune paraneoplastic gut dysmotility syndrome. American Society of Parenteral and Enteral Nutrition. Orlando: Abstract [Details]
(1992) A preliminary report on the distribution of Lp(a) among VLDL, LDL, and HDL particles separated by HPLC in subjects with NIDDM. Second International Lp(a) Conference.
O'Brien T, Nguyen TT, Kottke BA (1992) A preliminary report on the distribution of Lp(a) among VLDL, LDL, and HDL particles separated by HPLC in subjects with NIDDM. Second International Lp(a) Conference. New Orleans, La, USA: Abstract [Details]
(1992) Rapid separation of human plasma lipoprotein fractions with high performance liquid chromatography. 25th Annual Lofland Conference on Arterial Wall Metabolism.
Buithieu J, O'Brien T, Klein L, Nguyen T, Kottke BA (1992) Rapid separation of human plasma lipoprotein fractions with high performance liquid chromatography. 25th Annual Lofland Conference on Arterial Wall Metabolism. Boston: Abstract [Details]
(1992) Treatment of solitary toxic thyroid nodules: Surgery vs Radioiodine. American Association of Endocrine Surgeons.
O'Brien T, Gharib H, Suman V, van Heerden JA (1992) Treatment of solitary toxic thyroid nodules: Surgery vs Radioiodine. American Association of Endocrine Surgeons. Miami: Abstract [Details]
(1992) The use of HPLC with a heparin affinity column to separate apo E poor and apo E rich HDL subparticles. 25th Annual Lofland Conference on Arterial Wall Metabolism.
O'Brien T, Buithieu J, Klein L, Nguyen T, Kottke BA (1992) The use of HPLC with a heparin affinity column to separate apo E poor and apo E rich HDL subparticles. 25th Annual Lofland Conference on Arterial Wall Metabolism. Boston: Abstract [Details]
(1992) The application of Sudan - B Black for detection of lipoprotein fractions separated from plasma by high performance liquid chromatography. Sixteenth International Symposium on Column Liquid Chromatography.
Klein L, Buithieu J, O'Brien T, Nguyen TT, Kottke BA (1992) The application of Sudan - B Black for detection of lipoprotein fractions separated from plasma by high performance liquid chromatography. Sixteenth International Symposium on Column Liquid Chromatography. Baltimore, Md: Abstract [Details]
(1992) Lp(a) in NIDDM. European Atherosclerosis Society.
O'Brien T, Nguyen T, Harrison J, Bailey K, Dyck P, Kottke BA (1992) Lp(a) in NIDDM. European Atherosclerosis Society. Nice: Abstract [Details]
(1991) Is the hyperinsulinemia of insulinoma associated with hypertension and hypertriglyceridemia. European Association for the Study of Diabetes, Diabetalogia.
O'Brien T, Young WF, Palumbo PJ, O'Brien PC, Service FJ (1991) Is the hyperinsulinemia of insulinoma associated with hypertension and hypertriglyceridemia. European Association for the Study of Diabetes, Diabetalogia. Abstract [Details]
(1991) Cushings syndrome associated with production of CRH, ACTH, and ADH by a pheochromocytoma. American College of Physicians, Minnesota Affiliate: Minneapolis.
O'Brien T, Young WF, Davila DG, Scheitauer BW, VanHeerden JA, Kovacs K, Horvath E, Vale W (1991) Cushings syndrome associated with production of CRH, ACTH, and ADH by a pheochromocytoma. American College of Physicians, Minnesota Affiliate: Minneapolis. Abstract [Details]
(1990) Serum ferritin in newly diagnosed diabetes mellitus and poorly controlled diabetes mellitus. British Diabetic Association Diabetic Med.
O'Mahony MS, Cronin C, Dinneen SF, Murray DM, O'Brien T, O'Sullivan DJ (1990) Serum ferritin in newly diagnosed diabetes mellitus and poorly controlled diabetes mellitus. British Diabetic Association Diabetic Med. Abstract [Details]
(1989) Is biochemical screening of diabetics for hemochromatosis worthwhile. American Diabetes Association Diabetes.
O'Brien T, Barrett B, Murray DM, Dinneen S, O'Sullivan DJ (1989) Is biochemical screening of diabetics for hemochromatosis worthwhile. American Diabetes Association Diabetes. Abstract [Details]
(1988) Silent Myocardial Ischemia in Diabetes Mellitus. American College of Cardiology, J Am Coll Card.
O'Brien T, Murray DM, Mulrooney R, O'Sullivan DJ (1988) Silent Myocardial Ischemia in Diabetes Mellitus. American College of Cardiology, J Am Coll Card. Abstract [Details]
(1988) The Incidence and Mechanism of Silent Myocardial Ischemia in Patients with Diabetes Mellitus. British Diabetic Association Diabetic Med.
O'Brien T, Murray DM, Mulrooney R, Fennell WF, O'Sullivan DJ (1988) The Incidence and Mechanism of Silent Myocardial Ischemia in Patients with Diabetes Mellitus. British Diabetic Association Diabetic Med. Abstract [Details]
(1988) The incidence and mechanism of silent myocardial ischemia on exercise testing in diabetes mellitus. Irish Cardiac Society Irish J Med Sci.
O'Brien T (1988) The incidence and mechanism of silent myocardial ischemia on exercise testing in diabetes mellitus. Irish Cardiac Society Irish J Med Sci. Abstract [Details]
(1988) Autonomic dysfunction and silent myocardial ischemia in patients with diabetes mellitus. European Cardiology Society Eur Heart J.
Murray DP, O'Brien T, Mulrooney R, O'Sullivan DJ (1988) Autonomic dysfunction and silent myocardial ischemia in patients with diabetes mellitus. European Cardiology Society Eur Heart J. Abstract [Details]

ANET/COS

  Year Publication
(2009) European Journal of Cancer Supplements 7 (2), 89.
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) European Journal of Cancer Supplements 7 (2), 89. ANET/COS [Details]
(2008) European Journal of Cancer Supplements 6 (9).
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2008) European Journal of Cancer Supplements 6 (9). ANET/COS [Details]

Conference Paper

  Year Publication
(2015) A Multifactorial Approach Towards Enhanced Extracellular Matrix Deposition and Maintenance of Mesenchymal Stem Cell Phenotype using Macromolecular Crowding and Low Oxygen Tension.
Gaspar, D., Cigognini, D., Kumar, P., Satyam, A., Alagesan, S., Sanz-Noguéz, C., Griffin, M., O’Brien, T., Pandit, A. and Zeugolis, D. (2015) A Multifactorial Approach Towards Enhanced Extracellular Matrix Deposition and Maintenance of Mesenchymal Stem Cell Phenotype using Macromolecular Crowding and Low Oxygen Tension. Conference Paper [Details]
(2013) A Tuneable Microgel Platform for In Vivo Delivery of Mesenchymal Stem Cells.
Thomas, D., Fontana, G., Chen, X., Sanz, C., Madden, K., Quandamatteo, F., Dockery, P., O’Brien, T. and Pandit, A (2013) A Tuneable Microgel Platform for In Vivo Delivery of Mesenchymal Stem Cells. Conference Paper [Details]
(2012) Topical administration of allogeneic mesenchymal stem cells (MSCs) seeded in a collagen scaffold augments wound healing and increases angiogenesis in the diabetic ulcer. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE.
O'Loughlin, A,Mangesh, M,Creane, M,Vaughan, EE,Mooney, E,Shaw, G,Murphy, M,Dockery, P,Pandit, A,O'Brien, T (2012) Topical administration of allogeneic mesenchymal stem cells (MSCs) seeded in a collagen scaffold augments wound healing and increases angiogenesis in the diabetic ulcer. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. Conference Paper [Details]
(2012) Vessel derived stem cells contribute to endochondral ossification of atherosclerotic plaque. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE.
Leszczynska, A,Farrell, E,O'Doherty, A,O'Brien, FJ,O'Brien, T,Barry, FP,Murphy, JM (2012) Vessel derived stem cells contribute to endochondral ossification of atherosclerotic plaque. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. Conference Paper [Details]
(2011) P35 Angiogenic potential of clonal populations of human mesenchymal stem cells. IRISH JOURNAL OF MEDICAL SCIENCE.
Scott, J,Liew, A,Shaw, G,Murphy, M,Barry, F,O'Brien, T (2011) P35 Angiogenic potential of clonal populations of human mesenchymal stem cells. IRISH JOURNAL OF MEDICAL SCIENCE. Conference Paper [Details]
(2011) Mesenchymal stem cell therapy for diabetic foot ulceration. IRISH JOURNAL OF MEDICAL SCIENCE.
O'Loughlin, A,Kulkarni, M,Dockery, P,Shaw, G,Mooney, E,Murphy, M,Pandit, A,O'Brien, T (2011) Mesenchymal stem cell therapy for diabetic foot ulceration. IRISH JOURNAL OF MEDICAL SCIENCE. Conference Paper [Details]
(2010) Tracking Mesenchymal Stem Cell Homing to the Infarcted Heart after Intracoronary, Intravenous and Intramyocadial Delivery. HUMAN GENE THERAPY.
Duffy, G,Kavanagh, C,Coleman, C,Murphy, M,O'Brien, T,Barrett, HH,Barry, F,Liu, Z (2010) Tracking Mesenchymal Stem Cell Homing to the Infarcted Heart after Intracoronary, Intravenous and Intramyocadial Delivery. HUMAN GENE THERAPY. Conference Paper [Details]
(2010) Osteogenic and chondrogenic potential of blood vessel derived stem cells. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY.
Leszczynska, A,O'Doherthy, A,O'Brien, T,Murphy, M (2010) Osteogenic and chondrogenic potential of blood vessel derived stem cells. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. Conference Paper [Details]
(2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Fiachra T Martin, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2005) Optimisation of a Fibrin Scaffold for Sustained Release of an Adenoviral Gene Vector .
Breen, A, Strappe, P, Anilkumar, TV, O'Brien, T, Pandit, A. (2005) Optimisation of a Fibrin Scaffold for Sustained Release of an Adenoviral Gene Vector . Conference Paper [Details]
(2003) Adeno-Associated Virus (AAV) Mediated Gene Delivery to Vascular Cells in the Rabbit Carotid Artery Module. A Controlled Randomised Clinical Trial.. Sir Peter Freyer Memorial Lecture and Surgical Symposium in association with the Irish Society of Surgical Oncology * NUI,Galway.
Sen S, Bartlett J, Akhtar Y, Courtney, D, Sultan S. O'Brien T. (2003) Adeno-Associated Virus (AAV) Mediated Gene Delivery to Vascular Cells in the Rabbit Carotid Artery Module. A Controlled Randomised Clinical Trial.. Sir Peter Freyer Memorial Lecture and Surgical Symposium in association with the Irish Society of Surgical Oncology * NUI,Galway. Conference Paper [Details]

Conference Poster

  Year Publication
(2015) Multifactorial Approach Towards Enhanced Extracellular Matrix Deposition and Maintenance of Mesenchymal Stem Cell Phenotype Using Macromolecular Crowding and Low Oxygen Tension.
Gaspar, D., Cigonini, D., Kumar, P., Satyam, A., Alagesan, S., Sanz-Noguéz, C., Griffin, M., O’Brien, T., Pandit, A. and Zeugolis, D (2015) Multifactorial Approach Towards Enhanced Extracellular Matrix Deposition and Maintenance of Mesenchymal Stem Cell Phenotype Using Macromolecular Crowding and Low Oxygen Tension. Conference Poster [Details]
(2014) A Tuneable Microgel Platform to Modulate Angiocrine Responses In Stem Cells.
Thomas, D., Fontana, G., Chen, X, Sanz, C., Dockery, P., O'Brien, T. and Pandit, A (2014) A Tuneable Microgel Platform to Modulate Angiocrine Responses In Stem Cells. Conference Poster [Details]
(2014) Multifactorial Approach Enhancing Matrix Deposition and Maintenance of Mesenchymal Stem Cells Phenotype.
Cigognini, D., Kumar, P., Alagesan, S., Sanz-Nogues, C., Griffin, M., O’Brien, T., Pandit, A. and Zeugolis, D. (2014) Multifactorial Approach Enhancing Matrix Deposition and Maintenance of Mesenchymal Stem Cells Phenotype. Conference Poster [Details]
(2014) A Tuneable Microgel Platform for In Vivo Cell Delivery and Revascularization.
Thomas, D,Fontana, G,Chen, XZ,Sanz, C,Quondamatteo, F,Dockery, P,O'Brien, T,Pandit, A (2014) A Tuneable Microgel Platform for In Vivo Cell Delivery and Revascularization. Conference Poster [Details]
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR).
Roisin M. Dwyer, James Ryan, Ronan Havelin, John C. Morris, Cathal O'Flatharta, Brian Miller, Zhonglin Liu, Mark Foley, Harrison H. Barrett, Mary Murphy, Frank P. Barry, Timothy O'Brien and Michael J. Kerin. (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR). Conference Poster [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO. Conference Poster [Details]
(2008) Glial-Derived Neurotrophic Factor–Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells. SFN Meeting.
Gemma E. Rooney, Siobhan S. McMahon, Thomas Ritter, Yolanda Garcia, Nicolas Madigan, Alexander Flügel, Kim K. Nickander, Peter Dockery, Timothy O'Brien, Linda Howard, Anthony J. Windebank and Frank P. Barry. (2008) Glial-Derived Neurotrophic Factor–Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells. SFN Meeting. San Diego: Conference Poster [Details]
(2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord. ESGCT meeting Brugge.
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Lisa McGinley, Timothy O'Brien. (2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord. ESGCT meeting Brugge. Belgium: Conference Poster [Details]
(2008) Silencing Ng2 Inhibitory Factor And Its Effect On Dorsal Root Ganglia Neurite Outgrowth. Neuroscience Ireland Meeting NUI.
Eleanor Donnelly, Lisa Mcginley, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Nicolas Madigan, Gemma Rooney, Timothy O'Brien, Siobhan McMahon. (2008) Silencing Ng2 Inhibitory Factor And Its Effect On Dorsal Root Ganglia Neurite Outgrowth. Neuroscience Ireland Meeting NUI. Galway: Conference Poster [Details]
(2008) Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. Irish Society for Gene and Cell Therapy Meeting University College Cork.
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Lisa Mcginley, Timothy O'Brien. (2008) Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. Irish Society for Gene and Cell Therapy Meeting University College Cork. Conference Poster [Details]
(2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT).
Udo Greiser, Melissa Hoare, Tyrone Bowes, Roisin Dwyer, Daniel O'Toole, Kaveh Mashayekhi, Mary Murphy, Frank Barry and Timothy O'Brien (2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT). Conference Poster [Details]
(2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Irish Society for Gene and Cell Therapy Meeting University College Cork.
Siobhan S. McMahon, Silke Albermann , Gemma E. Rooney, Timothy O'Brien, Yolanda Garcia, Peter Dockery, Anthony J. Windebank, Timothy E. Allsopp, Frank P. Barry. (2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Irish Society for Gene and Cell Therapy Meeting University College Cork. Conference Poster [Details]
(2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Neuroscience Ireland Meeting.
Siobhan S. McMahon, Silke Albermann, Gemma E. Rooney, Timothy O'Brien, Yolanda Garcia, Peter Dockery, Anthony J. Windebank, Timothy E. Allsopp, Frank P. Barry. (2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Neuroscience Ireland Meeting. NUI Galway: Conference Poster [Details]
(2006) Lentiviral vector transduction efficiency and biosafety profile of adult mesenchymal stem cells. American Society of Gene Therapy Baltimore, Maryland, USA.
Barry M. McGrath, Ciara O'Shea, Linda Howard, Mary Murphy, Frank Barry, Timothy O'Brien (2006) Lentiviral vector transduction efficiency and biosafety profile of adult mesenchymal stem cells. American Society of Gene Therapy Baltimore, Maryland, USA. Conference Poster [Details]

Correction

  Year Publication
(2015) Expression of Concern: Human amniotic epithelial cells can differentiate into granulosa cells and restore folliculogenesis in a mouse model of chemotherapy-induced premature ovarian failure (vol 4, pg 124, 2013).
Tuan, RS,O'Brien, T (2015) Expression of Concern: Human amniotic epithelial cells can differentiate into granulosa cells and restore folliculogenesis in a mouse model of chemotherapy-induced premature ovarian failure (vol 4, pg 124, 2013). Correction [DOI] [Details]

Editorial

  Year Publication
(2015) Radiological remission and recovery of thirst appreciation after infliximab therapy in adipsic diabetes insipidus secondary to neurosarcoidosis.
O'Reilly, MW,Sexton, DJ,Dennedy, MC,Counihan, TJ,Finucane, FM,O'Brien, T,O'Regan, AW (2015) Radiological remission and recovery of thirst appreciation after infliximab therapy in adipsic diabetes insipidus secondary to neurosarcoidosis. Editorial [DOI] [Details]
(2015) Hypercalcaemic hyperparathyroid crisis.
Linane, H,Egan, AM,Griffin, TP,Quill, D,Phelan, SM,O'Brien, T (2015) Hypercalcaemic hyperparathyroid crisis. Editorial [DOI] [Details]
(2014) MSCs Isolated From Patients With Ischemic Vascular Disease Have Normal Angiogenic Potential.
Sanz-Nogues, C,O'Brien, T (2014) MSCs Isolated From Patients With Ischemic Vascular Disease Have Normal Angiogenic Potential. Editorial [DOI] [Details]
(2013) Three years of Stem Cell Research & Therapy.
Locke, P,O'Brien, T,Tuan, RS (2013) Three years of Stem Cell Research & Therapy. Editorial [DOI] [Details]
(2013) Gene Therapy for Type 1 Diabetes Moves a Step Closer to Reality.
O'Brien, T (2013) Gene Therapy for Type 1 Diabetes Moves a Step Closer to Reality. Editorial [DOI] [Details]
(2012) Stem Cell Research & Therapy in 2012.
Locke, P,Tuan, RS,O'Brien, T (2012) Stem Cell Research & Therapy in 2012. Editorial [DOI] [Details]
(2011) Stem Cell Research & Therapy marks its first anniversary.
Locke, P,O'Brien, T,Tuan, RS (2011) Stem Cell Research & Therapy marks its first anniversary. Editorial [DOI] [Details]
(2011) Stem Cell Therapy for Cardiac Disease. Expert Opinion on Biol Therapy.
Flynn A, O'Brien T (2011) Stem Cell Therapy for Cardiac Disease. Expert Opinion on Biol Therapy. Editorial [Details]
(2011) Stem cell therapy for cardiac disease.
Flynn, A,O'Brien, T (2011) Stem cell therapy for cardiac disease. Editorial [DOI] [Details]
(2010) Welcome to Stem Cell Research & Therapy.
Donnelly, A,Johar, S,O'Brien, T,Tuan, RS (2010) Welcome to Stem Cell Research & Therapy. Editorial [DOI] [Details]
(2010) Introduction to Series on Mesenchymal Stromal (Stem) Cells-MSCs.
O'Brien, T,Barry, F (2010) Introduction to Series on Mesenchymal Stromal (Stem) Cells-MSCs. Editorial [DOI] [Details]
(2009) Stem Cell Therapy and Regenerative Medicine.
O'Brien, T,Barry, FP (2009) Stem Cell Therapy and Regenerative Medicine. Editorial [Details]
(2004) When head rules heart.
Flaherty, G,Bell, M,O'Keeffe, D,Crowley, J,O'Brien, T (2004) When head rules heart. Editorial [Details]

Meeting

  Year Publication
(2013) Elucidating the role of homing MSC in cardiac healing and remodeling in an ex vivo model of myocardial infarction.
Siti-Ismail, N,Farrell, E,Kavanagh, C,O'Brien, T,Barry, F (2013) Elucidating the role of homing MSC in cardiac healing and remodeling in an ex vivo model of myocardial infarction. Meeting [Details]
(2013) Nuclear factor kappa-B inhibition attenuates acute but worsens prolonged pneumonia induced acute lung injury in Sprague-Dawley rats.
Devaney, J,Curley, GF,O'Brien, T,O'Toole, D,Laffey, G (2013) Nuclear factor kappa-B inhibition attenuates acute but worsens prolonged pneumonia induced acute lung injury in Sprague-Dawley rats. Meeting [Details]
(2012) ENHANCED ENDOCHONDRAL OSSIFICATION IN VESSEL DERIVED STEM CELLS BY ATHEROSCLEROTIC ENVIRONMENT.
Leszczynsk, A,O'Doherty, A,Farrell, E,O'Brien, F,O'Brien, T,Murphy, M (2012) ENHANCED ENDOCHONDRAL OSSIFICATION IN VESSEL DERIVED STEM CELLS BY ATHEROSCLEROTIC ENVIRONMENT. Meeting [DOI] [Details]
(2012) Topical allogeneic mesenchymal stem cell therapy for diabetic ulceration.
O'Loughlin, A,Kulkarni, M,Creane, M,Vaughan, EE,Mooney, E,Shaw, G,Murphy, M,Dockery, P,Pandit, A,O'Brien, T (2012) Topical allogeneic mesenchymal stem cell therapy for diabetic ulceration. Meeting [Details]
(2012) Topical administration of allogeneic mesenchymal stem cells (MSCs) seeded in a collagen scaffold augments wound healing and increases angiogenesis in the diabetic ulcer.
O'Loughlin, A,Mangesh, M,Creane, M,Vaughan, EE,Mooney, E,Shaw, G,Murphy, M,Dockery, P,Pandit, A,O'Brien, T (2012) Topical administration of allogeneic mesenchymal stem cells (MSCs) seeded in a collagen scaffold augments wound healing and increases angiogenesis in the diabetic ulcer. Meeting [Details]
(2012) Circulating Human Monocytes differ in Phenotype and Function According to Metabolic Profile in Obesity and Type 2 Diabetes Mellitus.
Dennedy, MC,Lopez, SP,Hanley, S,Connaughton, E,Slevin, S,Ceredig, R,O'Shea, D,O'Brien, T,Griffin, M (2012) Circulating Human Monocytes differ in Phenotype and Function According to Metabolic Profile in Obesity and Type 2 Diabetes Mellitus. Meeting [Details]
(2011) SYSTEMIC ROTENONE DOES NOT ENHANCE PARKINSONIAN PATHOLOGY CAUSED BY INTRACEREBRAL alpha-SYNUCLEIN IN RATS.
Mulcahy, PJ,O'Doherty, A,O'Brien, T,Kirik, D,Dowd, E (2011) SYSTEMIC ROTENONE DOES NOT ENHANCE PARKINSONIAN PATHOLOGY CAUSED BY INTRACEREBRAL alpha-SYNUCLEIN IN RATS. Meeting [Details]
(2011) AXONAL GROWTH IN THE CONTUSED RAT SPINAL CORD: PROMOTION BY NEUROTROPHIN-3 AND KNOCKDOWN OF NG2.
Kinnavane, L,Donnelly, E,Strappe, P,Dockery, P,Fraher, J,Windebank, T,O'Brien, T,McMahon, S (2011) AXONAL GROWTH IN THE CONTUSED RAT SPINAL CORD: PROMOTION BY NEUROTROPHIN-3 AND KNOCKDOWN OF NG2. Meeting [Details]
(2011) Identification of eNOS induced Hsp70 genes involved in the inhibition of human arterial smooth muscle cell proliferation.
McCullagh, K,Cooney, R,O'Brien, T (2011) Identification of eNOS induced Hsp70 genes involved in the inhibition of human arterial smooth muscle cell proliferation. Meeting [Details]
(2011) P35 Angiogenic potential of clonal populations of human mesenchymal stem cells.
Scott, J,Liew, A,Shaw, G,Murphy, M,Barry, F,O'Brien, T (2011) P35 Angiogenic potential of clonal populations of human mesenchymal stem cells. Meeting [Details]
(2010) OPN Exposure increases the angiogenic potential of endothelial progenitor cells.
Vaughan, EE,O'Loughlin, A,Duffy, A,O'Brien, T (2010) OPN Exposure increases the angiogenic potential of endothelial progenitor cells. Meeting [Details]
(2010) Gastric sleeve resection is a better bariatric surgical option when compared to laparoscopic adjustable gastric banding (LAP banding).
Crowe, C,Dennedy, MC,O'Neill, C,Dullea, KM,Griffin, H,McAnena, O,O'Brien, T (2010) Gastric sleeve resection is a better bariatric surgical option when compared to laparoscopic adjustable gastric banding (LAP banding). Meeting [Details]
(2010) Diabetes-related lower extremity amputation in an Irish tertiary referral hospital.
O'Loughlin, A,McIntosh, C,Dinneen, SF,O'Brien, T (2010) Diabetes-related lower extremity amputation in an Irish tertiary referral hospital. Meeting [Details]
(2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo.
Dwyer, R,Ryan, J,Havelin, R,Morris, J,O'Flatharta, C,Duffy, G,Miller, B,Liu, ZL,Barrett, H,Murphy, M,Barry, F,O'Brien, T,Kerin, M (2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. Meeting [Details]
(2009) Stem cell targeting strategies for cartilage repair in a functional osteoarthritic explant model.
Curtin, C,Murphy, M,Curtin, W,Dockery, P,O'Flatharta, C,O'Brien, T,Barry, F (2009) Stem cell targeting strategies for cartilage repair in a functional osteoarthritic explant model. Meeting [Details]
(2008) Aerosol delivery of AAV5-gfp to the rodent lung.
Mac Loughlin, R,Higgins, B,Laffey, J,O'Brien, T (2008) Aerosol delivery of AAV5-gfp to the rodent lung. Meeting [Details]
(2008) Viral vector mediated delivery of antioxidant and antiapoptotic proteins to mesenchymal stem cells.
McGinley, L,O'Toole, D,McMahon, J,Strappe, P,O'Brien, T (2008) Viral vector mediated delivery of antioxidant and antiapoptotic proteins to mesenchymal stem cells. Meeting [Details]
(2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs.
Greiser, U,Hoare, M,Bowes, T,Dwyer, R,O'Toole, D,Mashayekhi, K,Murphy, M,O'Brien, T,Barry, F (2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs. Meeting [Details]
(2008) Mesenchymal stem cells over-expressing ephrin-B2: A potential pro-angiogenic stem cell source.
Duffy, G,D'Arcy, S,Ahsan, T,Nerem, RM,O'Brien, T,Barry, F (2008) Mesenchymal stem cells over-expressing ephrin-B2: A potential pro-angiogenic stem cell source. Meeting [Details]
(2007) An alternative strategy to reduce instent restenosis and prevent late stent thrombosis through enhanced endothelial regeneration using eNOS gene-eluting stents.
Sharif, F,Hynes, SO,Cooney, R,Howard, L,Mcmahon, J,Daly, K,Crowley, J,Barry, F,O'brien, T (2007) An alternative strategy to reduce instent restenosis and prevent late stent thrombosis through enhanced endothelial regeneration using eNOS gene-eluting stents. Meeting [Details]
(2007) Delivery of therapeutic gene ENOS via a fibrin scaffold enhances wound healing in a compromised wound model.
Breen, A,Dockery, P,O'Brien, T,Pandit, A (2007) Delivery of therapeutic gene ENOS via a fibrin scaffold enhances wound healing in a compromised wound model. Meeting [Details]
(2007) Endothelial progenitor cell number: A novel concept in pathogenesis of increased cardiovascular risks in obstructive sleep apnoea syndrome.
Uzbeck, M,Liew, A,Mcdermott, J,Gallagher, D,Saleem, I,Avalos, G,Gilmartin, JJ,O'Brien, T (2007) Endothelial progenitor cell number: A novel concept in pathogenesis of increased cardiovascular risks in obstructive sleep apnoea syndrome. Meeting [Details]
(2004) Adenoviral mediated gene transfer of NOS isoforms and vascular cell proliferation.
Cooney, R,O'Brien, T (2004) Adenoviral mediated gene transfer of NOS isoforms and vascular cell proliferation. Meeting [Details]

Report

  Year Publication
(2012) A Benchmarking visit to Dundee by the School of Medicine- Educational and Organisational Outcomes.
Ashe DA, Cantillon P, Dunne F, Flaherty G, Kelly M, O’ Brien T,Wheatley A (2012) A Benchmarking visit to Dundee by the School of Medicine- Educational and Organisational Outcomes. NUI Galway: Report [Details]

Reviews

  Year Publication
(2016) In vitro models for assessing therapeutic angiogenesis.
Sanz-Nogues, C;O'Brien, T (2016) In vitro models for assessing therapeutic angiogenesis. OXFORD: Reviews [DOI] [Details]
(2015) Translating stem cell research to the clinic: a primer on translational considerations for your first stem cell protocol.
O'Brien, T,Creane, M,Windebank, AJ,Terzic, A,Dietz, AB (2015) Translating stem cell research to the clinic: a primer on translational considerations for your first stem cell protocol. Reviews [DOI] [Details]
(2011) Stem Cell Research & Therapy marks its first anniversary. Editorial Stem Cell Research & Therapy.
Locke P, O'Brien T, Tuar RS (2011) Stem Cell Research & Therapy marks its first anniversary. Editorial Stem Cell Research & Therapy. Reviews [Details]
(2010) Non-viral gene therapy for myocardial engineering.
Holladay, CA,O'Brien, T,Pandit, A (2010) Non-viral gene therapy for myocardial engineering. Reviews [DOI] [Details]
(2010) Journeys to High Altitude-Risks and Recommendations for Travelers with Preexisting Medical Conditions.
Mieske, K,Flaherty, G,O'Brien, T (2010) Journeys to High Altitude-Risks and Recommendations for Travelers with Preexisting Medical Conditions. Reviews [DOI] [Details]
(2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer.
Dwyer, RM,Khan, S,Barry, FP,O'Brien, T,Kerin, MJ (2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer. Reviews [DOI] [Details]
(2010) Relevance of an Academic GMP Pan-European Vector Infra-Structure (PEVI).
Cohen-Haguenauer, O,Creff, N,Cruz, P,Tunc, C,Aiuti, A,Baum, C,Bosch, F,Blomberg, P,Cichutek, K,Collins, M,Danos, O,Dehaut, F,Federspiel, M,Galun, E,Garritsen, H,Hauser, H,Hildebrandt, M,Klatzmann, D,Merten, OW,Montini, E,O'Brien, T,Panet, A,Rasooly, L,Scherman, D,Schmidt, M,Schweizer, M,Tiberghien, P,Vandendriessche, T,Ziehr, H,Yla-Herttuala, S,von Kalle, C,Gahrton, G,Carrondo, M (2010) Relevance of an Academic GMP Pan-European Vector Infra-Structure (PEVI). Reviews [Details]
(2010) Review paper: basic concepts to novel therapies: a review of the diabetic foot. Int J Low Extrem Wounds.
O'Loughlin A, McIntosh C, Dineen SF, O'Brien T (2010) Review paper: basic concepts to novel therapies: a review of the diabetic foot. Int J Low Extrem Wounds. Reviews [Details]
(2010) Liposomal gene delivery mediated by tissue-engineered scaffolds.
Kulkarni, M,Greiser, U,O'Brien, T,Pandit, A (2010) Liposomal gene delivery mediated by tissue-engineered scaffolds. Reviews [DOI] [Details]
(2010) Relevance of an Academic GMP Pan-European Vector Infra-structure (PEVI). Curr Gene Ther.
Odile Cohen-Haguenauer, Nicolas Creff, Pedro Cruz, Celia Tunc, Alessandro Aïuti, Christopher Baum, Fatima Bosch, Pontus Blomberg, Klaus Cichutek, Mary Collins, Olivier Danos, Frédéric Dehaut, Marc Federspiel, Eithan Galun, Henk Garritsen, Hansjörg Hauser, Martin Hildebrandt David Klatzmann, Otto Merten, Eugenio Montini, Tim O'Brien, Amos Panet, Linda Rasooly, Daniel Scherman, Manfred Schmidt, Matthias Schweitzer, Pierre Tiberghien, Thierry Vandendriessche, Holger Ziehr, Seppo Ylä-Herttuala, Christof von Kalle, Gösta Gahrton and Manuel Carrondo (2010) Relevance of an Academic GMP Pan-European Vector Infra-structure (PEVI). Curr Gene Ther. Reviews [Details]
(2010) Translation of science to surgery: linking emerging concepts in biological cartilage repair to surgical intervention. J Bone Joint Surg Br.
Moran CJ, Shannon FJ, Barry FP, O'Byrne JM, O'Brien T, Curtin W (2010) Translation of science to surgery: linking emerging concepts in biological cartilage repair to surgical intervention. J Bone Joint Surg Br. Reviews [Details]
(2010) Liposomal Gene Delivery Mediated by Tissue-Engineered Scaffolds. Trends Biotechnology.
Kulkarni M, Greiser U, O'Brien T, Pandit A (2010) Liposomal Gene Delivery Mediated by Tissue-Engineered Scaffolds. Trends Biotechnology. Reviews [Details]
(2010) Journeys to High Altitude- Risks and Recommendations for Travelers with Preexisting Medical Conditions. Journal of Travel Medicine.
Mieske K, Flaherty G, O'Brien T (2010) Journeys to High Altitude- Risks and Recommendations for Travelers with Preexisting Medical Conditions. Journal of Travel Medicine. Reviews [Details]
(2010) Introduction to Series on Mesenchymal Stromal (Stem) Cells-MSCs. Human Gene Therapy.
O'Brien T, Barry F (2010) Introduction to Series on Mesenchymal Stromal (Stem) Cells-MSCs. Human Gene Therapy. Reviews [Details]
(2010) Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries. Trials.
Kate Whitfiel, Karl-Heinz Huemer, Diana Winter, Steffen Thirstrup, Christian Libersa, Beatrice Barraud, Christine Kubiak, Lea Stankovski, Xina Grahlert, Gabriele Dreier, Sebastian Geismann, Wolfgang Kuchinke, Anke Strenge-Hesse, Zsuza Temesvari, Gyorgy Blasko, Gabriella Kardos, Timothy O'Brien, Margaret Cooney, Siobhan Gaynor, Arrigo Schieppati, Mariantonia Serrano, Fernando de Andres, Nuria Sanz, Raquel Hernandez, German Kreis, Charlotte Asker-Hagelberg, Hanna Johansson, Adeeba Asghar, Jean-Marc Husson, Jacques Demotes and Christian Gluud (2010) Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries. Trials. Reviews [Details]
(2010) Welcome to Stem Cell Research & Therapy. Stem Cell Res Ther.
Donnelly A, Johar S, O'Brien T, Tuan RS (2010) Welcome to Stem Cell Research & Therapy. Stem Cell Res Ther. Reviews [Details]
(2010) Non-viral gene therapy for myocardial engineering. Wiley Interdiscip Rev Nanomed Nanobiotechnol.
Holladay C, O'Brien T, Pandit A (2010) Non-viral gene therapy for myocardial engineering. Wiley Interdiscip Rev Nanomed Nanobiotechnol. Reviews [Details]
(2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer. Stem Cell Res Ther.
Dwyer RM, Khan S, Barry FP, O'Brien T, Kerin MJ (2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer. Stem Cell Res Ther. Reviews [Details]
(2009) Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules. Tissue Eng Part B Rev.
Breen A, O'Brien T, Pandit A (2009) Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules. Tissue Eng Part B Rev. Reviews [Details]
(2009) Mayo Clinic Proceedings. Stem Cell Therapy and Regenerative Medicine.
O'Brien T, Barry, FP (2009) Mayo Clinic Proceedings. Stem Cell Therapy and Regenerative Medicine. Reviews [Details]
(2009) When a nephrectomy cures hypoglycaemia. BMJ Case reports.
O'Loughlin A, Waldron-Lynch F, Cronin KC, Dineen S, Lee J, Griffin D, Casey M, Nusrat N, Jaffrey S, O'Brien T, Dunne F (2009) When a nephrectomy cures hypoglycaemia. BMJ Case reports. Reviews [Details]
(2009) Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules.
Breen, A,O'Brien, T,Pandit, A (2009) Fibrin as a Delivery System for Therapeutic Drugs and Biomolecules. Reviews [DOI] [Details]
(2009) Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds. Respir Physiol Neurobiol.
Madigan NN, O'Brien T, Yaszemski MJ, Windebank AJ (2009) Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds. Respir Physiol Neurobiol. Reviews [Details]
(2009) Nitric Oxide synthase gene therapy: progress and prospects. Expert Opinion on Biological Therapy.
O'Connor DM, O'Brien T (2009) Nitric Oxide synthase gene therapy: progress and prospects. Expert Opinion on Biological Therapy. Reviews [Details]
(2009) Nitric oxide synthase gene therapy: progress and prospects.
O'Connor, DM,O'Brien, T (2009) Nitric oxide synthase gene therapy: progress and prospects. Reviews [DOI] [Details]
(2008) Tripartite Meeting in Gene and Cell Therapy, 2008: Irish Society for Gene and Cell Therapy, British Society for Gene Therapy, and International Society for Cell and Gene Therapy of Cancer.
Guinn, B,Casey, G,Collins, S,O'Brien, T,Alexander, MY,Tangney, M (2008) Tripartite Meeting in Gene and Cell Therapy, 2008: Irish Society for Gene and Cell Therapy, British Society for Gene Therapy, and International Society for Cell and Gene Therapy of Cancer. Reviews [DOI] [Details]
(2008) Endothelial progenitor cells for the treatment of diabetic vasculopathy: panacea or pandora’s box?. Diabetes Obes Metab.
Liew, A, McDermott, JH, Barry, F, O'Brien, T (2008) Endothelial progenitor cells for the treatment of diabetic vasculopathy: panacea or pandora’s box?. Diabetes Obes Metab. Reviews [DOI] [Details]
(2008) Endothelial progenitor cells for the treatment of diabetic vasculopathy: panacea or Pandora's box?.
Liew, A,McDermott, JH,Barry, F,O'Brien, T (2008) Endothelial progenitor cells for the treatment of diabetic vasculopathy: panacea or Pandora's box?. Reviews [DOI] [Details]
(2008) Genetic engineering of the blood vessel wall to improve nitric oxide bioavailability. Bio-Medical Materials and Engineering.
O'Brien, T (2008) Genetic engineering of the blood vessel wall to improve nitric oxide bioavailability. Bio-Medical Materials and Engineering. Reviews [Details]
(2007) Cardiovascular gene therapy: current status and therapeutic potential. British journal of Pharmacology.
Gaffney, MM, Hynes, SO, Barry, F, O'Brien, T (2007) Cardiovascular gene therapy: current status and therapeutic potential. British journal of Pharmacology. Reviews [Details]
(2007) Cardiovascular gene therapy: current status and therapeutic potential.
Gaffney, MM,Hynes, SO,Barry, F,O'Brien, T (2007) Cardiovascular gene therapy: current status and therapeutic potential. Reviews [DOI] [Details]
(2007) UC-blood derived mesenchymal stromal cells: an overview. Cytotherapy.
Flynn A, Barry F, O'Brien T (2007) UC-blood derived mesenchymal stromal cells: an overview. Cytotherapy. Reviews [Details]
(2007) UC blood-derived mesenchyrnal stromal cells: an overview.
Flynn, A,Barry, F,O'Brien, T (2007) UC blood-derived mesenchyrnal stromal cells: an overview. Reviews [DOI] [Details]
(2007) The rational design of beta cell cytoprotective gene transfer strategies: targeting deleterious iNOS expression. Mol Biotechnol.
McCabe C, O'Brien T (2007) The rational design of beta cell cytoprotective gene transfer strategies: targeting deleterious iNOS expression. Mol Biotechnol. Reviews [Details]
(2007) Alferminogene Tadenovac, an angiogenic FGF4 gene therapy for coronary artery disease. IDrugs.
Flynn, A, O'Brien, T (2007) Alferminogene Tadenovac, an angiogenic FGF4 gene therapy for coronary artery disease. IDrugs. Reviews [Details]
(2006) Cytoprotection of beta cells: rational gene transfer strategies.
McCabe, C,Samali, A,O'Brien, T (2006) Cytoprotection of beta cells: rational gene transfer strategies. Reviews [DOI] [Details]
(2006) Cytoprotection of beta cells: rational gene transfer strategies. Diabetes Metab Res Rev.
McCabe C, Samali A, O'Brien T (2006) Cytoprotection of beta cells: rational gene transfer strategies. Diabetes Metab Res Rev. Reviews [Details]
(2006) Disorders of high-density lipoprotein cholesterol. Accepted by the American Association of Clinical Endocrinologists.
O'Brien, T (2006) Disorders of high-density lipoprotein cholesterol. Accepted by the American Association of Clinical Endocrinologists. Reviews [Details]
(2006) Review of High Density Lipoproteins. Endocrine Self-Assessment Committee of the American Medical Accreditation Program (AMAP) Research Committee.
O'Brien T (2006) Review of High Density Lipoproteins. Endocrine Self-Assessment Committee of the American Medical Accreditation Program (AMAP) Research Committee. Reviews [Details]
(2006) Preparing patients with diabetes for international travel. Modern Medicine.
Flaherty, G, Bell, M, Dunne, F, O'Brien, T (2006) Preparing patients with diabetes for international travel. Modern Medicine. Reviews [Details]
(2006) Public Awareness of the Health Risks Associated with Trekking to High Altitude. British Travel Health Association Journal.
Flaherty, G, Umeed, M, O'Brien, T, Fry, G (2006) Public Awareness of the Health Risks Associated with Trekking to High Altitude. British Travel Health Association Journal. Reviews [Details]
(2006) Reversible dilated cardiomyopathy: an unusual presentation of thyrotoxicosis. Ir Med J.
Flaherty G, Sharif F, Bell M, Daly K, O'Brien T (2006) Reversible dilated cardiomyopathy: an unusual presentation of thyrotoxicosis. Ir Med J. Reviews [Details]
(2005) Analysis of superoxide anion production in tissue. Methods Mol Med.
Zanetti M, d'Uscio LV, Peterson TE, Katusic ZS, O'Brien T (2005) Analysis of superoxide anion production in tissue. Methods Mol Med. Reviews [Details]
(2005) Gene transfer in endothelial dysfunction and hypertension. Methods Mol Med.
Sen S, Strappe PM, O'Brien T (2005) Gene transfer in endothelial dysfunction and hypertension. Methods Mol Med. Reviews [Details]
(2005) The malady of ascent – an overview of high altitude illness. Modern Medicine.
O'Brien, T, Flaherty, G (2005) The malady of ascent – an overview of high altitude illness. Modern Medicine. Reviews [Details]
(2005) Don’t Lose Heart – Therapeutic Value of Apoptosis Prevention in the Treatment of Cardiovascular Disease. Journal of Cellular and Molecular Medicine.
O'Brien, T Samali, A, Duffy, AM, Reeve, JL (2005) Don’t Lose Heart – Therapeutic Value of Apoptosis Prevention in the Treatment of Cardiovascular Disease. Journal of Cellular and Molecular Medicine. Reviews [Details]
(2005) Mesenchymal stem cell transplantation for tissue repair. Sem Plast Surg.
Barry FP, Murphy JM, O'Brien T, Mahon BP (2005) (2005) Mesenchymal stem cell transplantation for tissue repair. Sem Plast Surg. Reviews [Details]
(2005) Don't lose heart - therapeutic value of apoptosis prevention in the treatment of cardiovascular disease.
Reeve, JLV,Duffy, AM,O'Brien, T,Samali, A (2005) Don't lose heart - therapeutic value of apoptosis prevention in the treatment of cardiovascular disease. Reviews [Details]
(2004) Current status of catheter- and stent-based gene therapy.
Sharif, F,Daly, K,Crowley, J,O'Brien, T (2004) Current status of catheter- and stent-based gene therapy. Reviews [DOI] [Details]
(2004) Current status of catheter and stent-based gene therapy. Cardiovascular Research.
Sharif, F, Daly, K, Crowley, J, O'Brien, T, (2004) (2004) Current status of catheter and stent-based gene therapy. Cardiovascular Research. Reviews [Details]
(2004) When head rules heart. Lancet.
Flaherty G, Bell M, O'Keeffe D, Crowley J, T O'Brien (2004) When head rules heart. Lancet. Reviews [Details]
(2004) The role of dual blockade of the renin-angiotensin system in diabetic nephropathy. Diabeteswise.
Bell, M, O'Brien, T, Lappin, D (2004) (2004) The role of dual blockade of the renin-angiotensin system in diabetic nephropathy. Diabeteswise. Reviews [Details]
(2003) Mastopathy and Diabetes. Current Diabetes Reports.
Kudva Y, Reynolds CA, O'Brien T, Crotty TB (2003) Mastopathy and Diabetes. Current Diabetes Reports. Reviews [Details]
(2003) Improving endothelial dysfunction in diabetes mellitus. Irish Medical News.
Sen S, O'Brien T (2003) Improving endothelial dysfunction in diabetes mellitus. Irish Medical News. Reviews [Details]
(2002) Clinical Trials in Vascular Gene Therapy: The Missing Piece of the Puzzle. Archives of Pathology and Laboratory Medicine.
Simari, RD, O'Brien, T (2002) Clinical Trials in Vascular Gene Therapy: The Missing Piece of the Puzzle. Archives of Pathology and Laboratory Medicine. Reviews [Details]
(2001) Clinical Applications of Vascular Gene Transfer. Current Cardiology Reports.
Simari RD, O'Brien T (2001) Clinical Applications of Vascular Gene Transfer. Current Cardiology Reports. Reviews [Details]
(2001) Low-density-lipoprotein apheresis: Therapy for refractory hyperlipidemia. Mayo Clinic Proceedings.
Vella A, Pineda A, O'Brien T (2001) Low-density-lipoprotein apheresis: Therapy for refractory hyperlipidemia. Mayo Clinic Proceedings. Reviews [Details]
(2000) Gene therapy for cardiovascular disease: A time for optimism and caution. Mayo Clinic Proceedings.
O'Brien T, Simari RD (2000) Gene therapy for cardiovascular disease: A time for optimism and caution. Mayo Clinic Proceedings. Reviews [Details]
(2000) Adenoviral vectors and gene transfer to the blood vessel wall. Editorial Arterioscler Throm Vasc Biol.
O'Brien T (2000) Adenoviral vectors and gene transfer to the blood vessel wall. Editorial Arterioscler Throm Vasc Biol. Reviews [Details]
(1999) Gene therapy for type I diabetes. J It Diabetology.
Zanetti M, O'Brien T, Palumbo PJ (1999) Gene therapy for type I diabetes. J It Diabetology. Reviews [Details]
(1999) Early and aggressive intervention to prevent heart disease in diabetes mellitus. Patient Care.
Ganda O, Hill Golden S, O'Brien T (1999) Early and aggressive intervention to prevent heart disease in diabetes mellitus. Patient Care. Reviews [Details]
(1999) The effects of hormonal therapy on plasma lipids and the risk of coronary artery disease in women. Medical Updates on Therapy, Diagnosis and Prevention, J American International Health Council.
O'Brien T (1999) The effects of hormonal therapy on plasma lipids and the risk of coronary artery disease in women. Medical Updates on Therapy, Diagnosis and Prevention, J American International Health Council. Reviews [Details]
(1999) Parenteral feeding in a patient with hypertriglyceridemia and increased liver enzyme levels. Endocrine Practice.
Leung N, O'Brien T, McMahon MM (1999) Parenteral feeding in a patient with hypertriglyceridemia and increased liver enzyme levels. Endocrine Practice. Reviews [Details]
(1998) Women and diabetes: Special health concerns. Patient Care.
Bashoff EC, Johnson LM, Jovanovic L, LaRosa JC, O'Brien T (1998) Women and diabetes: Special health concerns. Patient Care. Reviews [Details]
(1998) Transfer and expression of recombinant nitric oxide synthase genes in the cardiovascular system. Trends in Pharmacological Sciences.
Chen AFY, O'Brien T, Katusic ZS (1998) Transfer and expression of recombinant nitric oxide synthase genes in the cardiovascular system. Trends in Pharmacological Sciences. Reviews [Details]
(1998) Hyperlipidemia and diabetes mellitus. Mayo Clinic Proceedings.
O'Brien T, Nguyen TT, Zimmerman B (1998) Hyperlipidemia and diabetes mellitus. Mayo Clinic Proceedings. Reviews [Details]
(1998) Pathogenic role of triglycerides in the cardiovascular disease of type 2 diabetes mellitus. Current Opinion in Endocrinology and Diabetes.
O'Brien T, Nguyen TT (1998) Pathogenic role of triglycerides in the cardiovascular disease of type 2 diabetes mellitus. Current Opinion in Endocrinology and Diabetes. Reviews [Details]
(1998) Gene transfer and vascular disease. Journal of the Irish College of Physicians and Surgeons.
O'Brien T (1998) Gene transfer and vascular disease. Journal of the Irish College of Physicians and Surgeons. Reviews [Details]
(1997) Lp(a) and diabetes mellitus. Endocrine Practice.
O'Brien T (1997) Lp(a) and diabetes mellitus. Endocrine Practice. Reviews [Details]
(1997) Unusual manifestations of type 1 autoimmune polyendocrinopathy. Ir Med J.
O'Sullivan DJ, Cronin C, Buckley D, Mitchell TM, Jenkins DJ, Greally J, O'Brien T (1997) Unusual manifestations of type 1 autoimmune polyendocrinopathy. Ir Med J. Reviews [Details]
(1997) Lipids and lipoproteins in women. Mayo Clin Proc.
O'Brien T, Nguyen TT (1997) Lipids and lipoproteins in women. Mayo Clin Proc. Reviews [Details]
(1996) The influence of hormones on lipids in women. PrimePractice.
O'Brien T (1996) The influence of hormones on lipids in women. PrimePractice. Reviews [Details]
(1993) Hyperlipidemia and diabetes mellitus. G Ital Diabetol.
O'Brien T, Palumbo PJ (1993) Hyperlipidemia and diabetes mellitus. G Ital Diabetol. Reviews [Details]
(1992) Cushing's syndrome associated with ectopic production of corticotrophin-releasing hormone, corticotrophin and vasopressin by a pheochromocytoma. Clin Endocrinol.
O'Brien T, Young WF, Davilla DG, Scheitauer BW, Kovacs K, Horvath E, Vale W, van Heerden JA (1992) Cushing's syndrome associated with ectopic production of corticotrophin-releasing hormone, corticotrophin and vasopressin by a pheochromocytoma. Clin Endocrinol. Reviews [Details]
(1992) Nicotinic acid-induced toxicity associated with cytopenia and decreased levels of thyroxine-binding globulin. Mayo Clin Proc.
O'Brien T, Silverberg J, Nguyen T (1992) Nicotinic acid-induced toxicity associated with cytopenia and decreased levels of thyroxine-binding globulin. Mayo Clin Proc. Reviews [Details]
(1991) A case of pregnancy associated osteoporosis and empty sella syndrome. Irish Medical Journal.
Kinsella P, O'Brien T, Brosnan E, O'Sullivan DJ (1991) A case of pregnancy associated osteoporosis and empty sella syndrome. Irish Medical Journal. Reviews [Details]
(1990) Fabry's Disease: A Family Study. Irish J Med Sci.
O'Brien T, Bolster M, Sullivan P (1990) Fabry's Disease: A Family Study. Irish J Med Sci. Reviews [Details]

Honours and Awards

  Year Title Awarding Body
2011 UCC Medical School Medal University College Cork
2009 Mayne Lecture Trinity College Dublin
2007 Nordisk Lecture Irish Endocrine Society
2005 Stokes Medal Irish Cardiac Society
1998 Young Investigator Award.
1997 Outstanding Poster Presentation.
1994 Mayo Foundation Scholar Mayo Graduate Schoold of Medicine
1993 Sprague Award for Excellence in Clinical Medicine
1992 Wl Stepohenson Fellowship in Clinical Nutrition Mayo Clinic Graduate School of Medicine
1988 Ainsworth Scholarship University College Cork
1978 College Scholar University College Cork
0 Mayo Clinic Internal Medicine Research Award: Mayo Clinic U.S.A.
0 Graves Lecturer Royal Academy of Medicine

Current Postgraduate Students (Research)

  Student Degree Type Type
Joshua Chao Doctorate - Structured Ph.D (Medicine) Supervisor