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Dr Karen Doyle

B.Sc., Ph.D.

Contact Details

Professor
Dept. of Physiology
Human Biology Building
University of Galway
E: karen.doyle@universityofgalway.ie
 
researcher
 

Biography

Karen Doyle is Professor in the School of Medicine and Principal Investigator. Her research involves studying neurovascular stress, the causes of neuronal loss and investigating novel strategies to protect brain tissue from damage.  Prof Doyle’s focus is on understanding the pathophysiology of occlusive stroke and the characteristics of human blood clots that cause occlusive strokes.       

Prof Doyle is President of Neuroscience Ireland (2021 - present), is the Founder and first Director of Galway Neuroscience Centre (2004 – 2009), and previously served as Vice Dean for Graduate Studies in the College of Medicine, Nursing & Health Sciences, NUI Galway (2011–2015). She is a member of the Governing Council of the Federation of European Neuroscience Societies (FENS; 2021 - present) and the FENS Committee for Higher Education & Training (2022 - present). Prof Doyle is also a member of the Governing Council of International Brain Research Organisation (IBRO; 2021 - present) and is a member of the European Stroke Organisation Membership Committee (2020 - present). Prof Doyle is on the Editorial Board of Frontiers in Stroke and PlosOne. Prof Doyle is a previous recipient of the Presidents Award for Teaching Excellence in NUI Galway (2015) and winner of a National Teaching Experts Award, from the National Forum for the Enhancement of Teaching and Learning in Higher Education (2015).    

Research Interests

Research Interests: 
My research focus is on understanding neurovascular stress, the pathophysiology of stroke and the characteristics of acute ischaemic stroke blood clots.

My current work through CURAM, working with clinical collaborators and a local medical device company, Cerenovus, correlates biomarkers we have identified in acute ischaemic stroke (AIS) blood clots with clinical procedural data and patient outcome. The composition of blood clots can vary considerably, and clot composition has an immense impact on how readily an AIS clot can be dissolved by thrombolytics, or physically removed by mechanical thrombectomy medical devices. The aim of this work is to identify biomarkers that will guide clinical interventionists on the best approach in order to most efficiently remove an AIS clot following a stroke, and to inform future medical device design, particularly to improve the recanalisation of cerebral vessels blocked by difficult to remove clots. I also collaborate with a medical device company in Paris, Sensome, to develop an electrical impedance sensor capable of predicting clot structure in advance of acute stroke treatment.

My research also focuses on understanding the causes of neuronal death, and novel neuroprotective strategies to prevent neuronal death, particularly related to stroke.  My previous work has touched on an array of neurological and psychiatric conditions including epilepsy, bipolar depression and the brain damage caused by drugs of abuse. In particular I have made a substantial contribution to the fields of polyamine and stroke research.

Research Projects

  Project Start Date End Date
Perfect 01-SEP-20 01-JUL-27
CURAM - Sensome SAS - Correlation of clot compositional analysis with impedance-based measurements - Industry Portion 01-DEC-19 01-AUG-22
CURAM - Sensome SAS - Correlation of clot compositional analysis with impedance-based measurements - SFI Portion 01-DEC-19 01-AUG-22
CURAM SPOKE NEURAVI LIMITED- EXCELLENT PROJECT 1 of 1 01-JUL-19 30-JUN-21
CURAM SPOKE SENSOME SAS - 1 of 1 01-JUL-19 31-DEC-20
CURAM SPOKE NEURAVI LIMITED - SPERO PROJECT 1 of 1 01-JUN-19 30-JUN-21
CURAM SPOKE NEURAVI LIMITED - 1 of 2 01-SEP-16 30-SEP-21
CURAM SPOKE NEURAVI LIMITED - 2 of 2 01-SEP-16 30-SEP-21
Impact of different Reperfusion Approach on Haemorrhagic Transformation Development Following an Aute Occlusive Stroke 01-MAR-15 31-MAY-17
Neuravi Ltd - EI IP 01-MAR-15 31-MAY-19
GALWAY N KAREN DOYLE 20-MAY-09 01-DEC-11
BEAUTY NEUROSCIENCE K DOYLE 01-FEB-09 30-SEP-09

Contract Researchers

  Researcher Name Project Role Funding Body
Dr Smita Patil AIS clot composition and impedance Postdoctoral Scientist Science Foundation Ireland (SFI)
Dr Madalina Mereuta Acute ischaemic stroke clot study Postdoctoral researcher Science Foundation Ireland (SFI)
Dr Cansu Sahin AIS clot composition and impedance Postdoctoral Scientist Science Foundation Ireland (SFI)
Dr Nazan Guner-Sak Diagnostic potential of electrical impedance for stroke clot characteristics Postdoctoral scientist Science Foundation Ireland (SFI)
Dr Sean Fitzgerald Acute ischaemic stroke clot pathology Postdoctoral Scientist Science Foundation Ireland (SFI)
Dr Rosanna Rossi Acute ischaemic stroke clot study Postdoctoral researcher Science Foundation Ireland (SFI)
Mr Adam Poyntz Acute ischaemic stroke clot pathology Research Assistant Science Foundation Ireland (SFI)
Mr Andrew Douglas Acute ischaemic stroke clot pathology Research Assistant Science Foundation Ireland (SFI)
Dr Jennifer Shearer Does different reperfusion approach have an impact on haemorrhage transformation development following an acute occlusive stroke? Postdoctoral Scientist Enterprise Ireland (EI)

Peer Reviewed Journals

  Year Publication
(2023) 'White blood cell subtypes and neutrophil extracellular traps content as biomarkers for stroke etiology in acute ischemic stroke clots retrieved by mechanical thrombectomy'
Duaa Jabrah, Rosanna Rossi, Sara Molina, Andrew Douglas, Abhay Pandit, Ray McCarthy, Michael Gilvarry, Eric Ceder, Seán Fitzgerald, Dennis Dunker, Annika Nordanstig, Petra Redfors, Turgut Tatlisumak, Alan O¿Hare, Sarah Power, Paul Brennan, Peter Owens, András Nagy, Ágnes Vadász, Simon F. De Meyer, Georgios Tsivgoulis, Klearchos Psychogios, Istvan Szikora, Katarina Jood, Alexandros Rentzos, John Thornton, Karen Doyle (2023) 'White blood cell subtypes and neutrophil extracellular traps content as biomarkers for stroke etiology in acute ischemic stroke clots retrieved by mechanical thrombectomy'. Thrombosis Research, [DOI] [Details]
(2023) 'White blood cell subtypes and neutrophil extracellular traps content as biomarkers for stroke etiology in acute ischemic stroke clots retrieved by mechanical thrombectomy'
Duaa Jabrah, Rosanna Rossi, Sara Molina, Andrew Douglas, Abhay Pandit, Ray McCarthy, Michael Gilvarry, Eric Ceder, Seán Fitzgerald, Dennis Dunker, Annika Nordanstig, Petra Redfors, Turgut Tatlisumak, Alan O¿Hare, Sarah Power, Paul Brennan, Peter Owens, András Nagy, Ágnes Vadász, Simon F. De Meyer, Georgios Tsivgoulis, Klearchos Psychogios, Istvan Szikora, Katarina Jood, Alexandros Rentzos, John Thornton, Karen Doyle (2023) 'White blood cell subtypes and neutrophil extracellular traps content as biomarkers for stroke etiology in acute ischemic stroke clots retrieved by mechanical thrombectomy'. Thrombosis Research, [DOI] [Details]
(2023) 'S100b in Acute Ischemic Stroke clots is a biomarker for post-thrombectomy intracranial hemorrhage'
Rosanna Rossi, Andrew Douglas, Sara Molina, Duaa Jabrah, Abhay Pandit, Michael Gilvarry, Ray McCarthy, James Prendergast, Katarina Jood, Petra Redfors, Annika Nordanstig, Erik Ceder, Dennis Dunker, Jeanette Carlqvist, István Szikora, John Thornton, Georgios Tsivgoulis, Klearchos Psychogios, Turgut Tatlisumak, Alexandros Rentzos, Karen M. Doyle (2023) 'S100b in Acute Ischemic Stroke clots is a biomarker for post-thrombectomy intracranial hemorrhage'. Frontiers In Neurology, [DOI] [Details]
(2023) 'Clot Composition and Recanalization Outcomes in Mechanical Thrombectomy'
Raul G. Nogueira, Agostinho Pinheiro, Waleed Brinjikji, Jorge Arturo Larco, Al-Hamza Al-Bayati, Mahmoud H Mohammaden, Lorena S Viana, Felipe M. Ferreira, Hend M Abdelhamid, Nirav Bhatt, Peter Kvamme, Kennith F Layton, Josser E Delgado Almandoz, Ricardo A Hanel, Vitor Mendes Pereira, Mohammed A Almekhlafi, Albert J Yoo, Babak S Jahromi, Matthew J Gounis, Biraj Patel, Mehdi Abbasi, Seán Fitzgerald, Oana Madalina Mereuta, Karen Doyle, Luis Savastano, Harry J Cloft, Ike C Thacker, Yasha Kayan, Alexander Copelan, Amin Aghaebrahim, Eric Sauvageau, Andrew M Demchuk, Parita Bhuva, Jazba Soomro, Pouya Nazari, Donald Robert Cantrell, Ajit S Puri, John Entwistle, Eric C Polley, Michael R Frankel, David F Kallmes, Diogo C Haussen (2023) 'Clot Composition and Recanalization Outcomes in Mechanical Thrombectomy'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2023) 'Identifying ex vivo acute ischemic stroke thrombus composition using electrochemical impedance spectroscopy'
Darcourt J, Brinjikji W, François O, Giraud A, Johnson CR, Patil S, Staessens S, Kadirvel R, Mohammaden MH, Pisani L, Rodrigues GM, Cancelliere NM, Pereira VM, Bozsak F, Doyle K, De Meyer SF, Messina P, Kallmes D, Cognard C, Nogueira RG (2023) 'Identifying ex vivo acute ischemic stroke thrombus composition using electrochemical impedance spectroscopy'. Interventional Neuroradiology, [DOI] [Details]
(2023) 'Endotheliitis and Cytokine Storm as a Mechanism of Clot Formation in COVID-19 Ischemic Stroke Patients: A Histopathologic Study of Retrieved Clots'
Waleed Brinjikji, David F. Kallmes, Renu Virmani, Simon F. de Meyer, Albert J. Yoo, William Humphries, Osama O. Zaidat, Mohamed S. Teleb, Jesse G. Jones, Adnan H. Siddiqui, Tommy Andersson, Raul G. Nogueira, Sara Molina Gil, Andrew Douglas, Rosanna Rossi, Alexander Rentzos, Erik Ceder, Jeanette Carlqvist, Dennis Dunker, Katarina Jood, Turgut Tatlisumak, Karen M. Doyle (2023) 'Endotheliitis and Cytokine Storm as a Mechanism of Clot Formation in COVID-19 Ischemic Stroke Patients: A Histopathologic Study of Retrieved Clots'. Interventional Neuroradiology, [DOI] [Details]
(2023) 'NIMBUS Geometric Clot Extractor for challenging clots: Real-world clinical experience and clot composition'
Hannes Nordmeyer, Nebiyat Filate Belachew, T. Phung, Jan Gralla, Sara Molina Gil, Andrew Douglas, S. Neuhaus, Patrick Haage, Karen Doyle, Pasquale Mordasini (2023) 'NIMBUS Geometric Clot Extractor for challenging clots: Real-world clinical experience and clot composition'. Interventional Neuroradiology, [DOI] [Details]
(2023) 'S100b in acute ischemic stroke clots is a biomarker for post-thrombectomy intracranial hemorrhages'
Rossi, Rosanna, Douglas, Andrew, Gil, Sara Molina, Jabrah, Duaa, Pandit, Abhay, Gilvarry, Michael, McCarthy,Ray, Prendergast, James, Jood, Katarina, Redfors, Petra, Nordanstig, Annika, Ceder, Erik, Dunker, Dennis, Carlqvist, Jeanette, Szikora, István, Thornton, John, Tsivgoulis, Georgios, Psychogios, Klearchos, Tatlisumak, Turgut, Rentzos, Alexandros, Doyle, Karen M (2023) 'S100b in acute ischemic stroke clots is a biomarker for post-thrombectomy intracranial hemorrhages'. Frontiers In Neurology, [DOI] [ARAN Link] [Details]
(2022) 'Detection, Diagnosis and Treatment of Acute Ischemic Stroke: Current and Future Perspectives'
Patil, Smita, Rossi, Rosanna, Jabrah, Duaa, & Doyle, Karen (2022) 'Detection, Diagnosis and Treatment of Acute Ischemic Stroke: Current and Future Perspectives'. Frontiers In Cardiovascular Medicine, [DOI] [ARAN Link] [Details]
(2022) 'Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives'
Smita Patil, Rosanna Rossi, Duaa Jabrah, Karen Doyle (2022) 'Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives'. Frontiers In Medicine, [DOI] [Details]
(2022) 'Characterising Acute Ischaemic Stroke Thrombi: Insights from Histology, Imaging and Emerging Impedance Based Technologies'
Smita Patil, Jean Darcourt, Pierluca Messina, Franz Bozniak, Christophe Cognard, Karen Doyle (2022) 'Characterising Acute Ischaemic Stroke Thrombi: Insights from Histology, Imaging and Emerging Impedance Based Technologies'. Stroke, [DOI] [Details]
(2022) 'Potential biomarkers of Acute Ischemic Stroke etiology revealed by mass spectrometry based proteomic characterization of formalin-fixed paraffin-embedded blood clots'
Rosanna Rossi, Oana Madalina Mereuta, Mariel Barbachan E Silva, Sara Molina Gil, Andrew Douglas, Abhay Pandit, Michael Gilvarry, Ray Mccarthy, Shane O'connell, Ciara Tierney, Klearchos Psychogios, Georgios Tsivgoulis, István Szikora, Turgut Tatlisumak, Alexandros Rentzos, John Thornton, Pilib O'Broin and Karen Doyle (2022) 'Potential biomarkers of Acute Ischemic Stroke etiology revealed by mass spectrometry based proteomic characterization of formalin-fixed paraffin-embedded blood clots'. Frontiers In Neurology, [DOI] [ARAN Link] [Details]
(2022) 'Cancer and stroke: commonly encountered by clinicians, but little evidence to guide clinical approach'
Woock, Malin; Martinez-Majander, Nicolas; Seiffge, David; Selvik, Aurora; Nordanstig, Annika; Redfors, Petra; Lindgren, Erik; Sanchez van Kammen, Mayte; Rentzos, Alexandros; Coutinho, Jonathan; Doyle, Karen; Næss, Halvor; Putaala, Jukka; Jood , Katarina ; Tatlisumak, Turgut (2022) 'Cancer and stroke: commonly encountered by clinicians, but little evidence to guide clinical approach'. Therapeutic advances in neurological disorders, [DOI] [Details]
(2022) 'Implications of COVID-19 to stroke medicine: an epidemiological and pathophysiological perspective'
King, Alan & Doyle, Karen M (2022) 'Implications of COVID-19 to stroke medicine: an epidemiological and pathophysiological perspective'. Current Vascular Pharmacology, [DOI] [Details]
(2022) 'MicroCT can characterize clots retrieved with mechanical thrombectomy from acute ischemic stroke patients ¿ a preliminary report'
Daniela Dumitriu LaGrange, Vincent Braunersreuther, Isabel Wanke, Jatta Berberat, Siri Luthman, Sean Fitzgerald, Karen Doyle, Olivier Brina, Philippe Reymond, Alexandra Platon, Michel Muster, Paolo Machi, Pierre-Alexandre Poletti, Maria Isabel Vargas, Karl-Olof Lovblad (2022) 'MicroCT can characterize clots retrieved with mechanical thrombectomy from acute ischemic stroke patients ¿ a preliminary report'. Frontiers In Neurology, [DOI] [Details]
(2022) 'Does prior administration of rtPA influence acute ischemic stroke clot composition? Findings from the analysis of clots retrieved with mechanical thrombectomy from the RESTORE registry'
Rosanna Rossi, Sara Molina, Andrew Douglas, Oana Madalina Mereuta, Seán Fitzgerald, Ciara Tierney, Abhay Pandit, Paul Brennan, Sarah Power, Alan O¿Hare, Michael Gilvarry, Ray McCarthy, Georgios Magoufis, Georgios Tsivgoulis, András Nagy, Ágnes Vadász, Katarina Jood, Petra Redfors, Annika Nordanstig, Erik Ceder, Dennis Dunker, Jeanette Carlqvist, Klearchos Psychogios, István Szikora, Turgut Tatlisumak, Alexandros Rentzos, John Thornton, Karen M. Doyle (2022) 'Does prior administration of rtPA influence acute ischemic stroke clot composition? Findings from the analysis of clots retrieved with mechanical thrombectomy from the RESTORE registry'. Journal Of Neurology, [DOI] [ARAN Link] [Details]
(2022) 'Histological composition of retrieved emboli in acute ischemic stroke is independent of pre-thrombectomy alteplase use'
Waleed Brinjikji; Mehdi Abbasi; Oana Madalina Mereuta; Sean Fitzgerald; Daying Dai; Ramanathan Kadirvel; Raul G Nogueira; Peter Kvamme; Kennith F Layton; Josser E. Delgado; Ricardo A Hanel; Vitor M Pereira; Mohammed A Almekhlafi; Albert J Yoo; Babak S Jahromi; Matthew J Gounis; Biraj M Patel; Luis E Savastano; Harry J Cloft; Diogo C Haussen; Alhamza Al-Bayati; Mahmoud Mohammaden; Leonardo Pisani; Gabriel Rodrigues; Ike C Thacker; Yasha Kayan; Alexander Z Copelan; Amin Aghaebrahim; Eric Sauvageau; Andrew M Demchuk; Parita Bhuva; Jazba Soomro; Pouya Nazari; Donald Robert Cantrell; Ajit S Puri; Karen M Doyle; John Entwistle; David Kallmes (2022) 'Histological composition of retrieved emboli in acute ischemic stroke is independent of pre-thrombectomy alteplase use'. Journal Of Stroke & Cerebrovascular Diseases, [DOI] [Details]
(2022) 'Histological evaluation of acute ischemic stroke thrombi may indicate vessel wall injury during mechanical thrombectomy'
Oana Mereuta, Mehdi Abbasi, Seán Fitzgerald, Daying Dai, Ram Kadirvel, Ricardo Hanel, Albert Yoo, Mohammed Almekhlafi, Kennith Layton, Josser Delgado Almandoz, Peter Kvamme, Vitor Mendes Pereira, Babak Jahromi, Raul Nogueira, Matthew Gounis, Biraj Patel, Amin Aghaebrahim, Eric Sauvageau, Parita Bhuva, Jazba Soomro, Andrew Demchuk, Ike Thacker, Yasha Kayan, Alexander Copelan, Pouya Nazari, Donald Cantrell, Diogo Haussen, Alhamza Al-Bayati, Mahmoud Mohammaden, Leonardo Pisani, Gabriel Rodrigues, Ajit Puri, John Entwistle, Alexander Meves, Jorge Arturo Larco, Luis Savastano, Harry Cloft, David Kallmes, Karen Doyle, and Waleed Brinjikji (2022) 'Histological evaluation of acute ischemic stroke thrombi may indicate vessel wall injury during mechanical thrombectomy'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2021) 'Novel human acute ischemic stroke blood clot analogues for in-vitro testing'
Seán Fitzgerald, Daying Dai, Oana Madalina Mereuta, Mehdi Abbasi, Andrew Douglas, David Kallmes, Karen M. Doyle, Waleed Brinjikji (2021) 'Novel human acute ischemic stroke blood clot analogues for in-vitro testing'. American Journal Of Neuroradiology, [DOI] [Details]
(2021) 'Studying stroke thrombus composition after thrombectomy: what can we learn?'
Senna Staessens, Olivier Francois, Waleed Brinjikji, Karen M. Doyle, Peter Vanacker, Tommy Andersson, Simon F. DeMeyer (2021) 'Studying stroke thrombus composition after thrombectomy: what can we learn?'. Stroke, [DOI] [Details]
(2021) 'Quantification of clot spatial heterogeneity and its impact on thrombectomy'
Yang Liu, Waleed Brinjikji, Mehdi Abbasi, Daying Dai, Jorge L Arturo Larco, Sarosh Irfan Madhani, Adnan H Shahid, Oana Madalina Mereuta, Raul G Nogueira, Peter Kvamme, Kennith F Layton, Josser E Delgado Almandoz, Ricardo A Hanel, Vitor Mendes Pereira, Mohammed A Almekhlafi, Albert J Yoo, Babak S Jahromi, Matthew J Gounis, Biraj Patel, Seán Fitzgerald, Karen Doyle, Diogo C Haussen, Alhamza R Al-Bayati, Mahmoud Mohammaden, Leonardo Pisani, Gabriel Martins Rodrigues, Ike C Thacker, Yasha Kayan, Alexander Copelan, Amin Aghaebrahim, Eric Sauvageau, Andrew M Demchuk, Parita Bhuva, Jazba Soomro, Pouya Nazari, Donald Robert Cantrell, Ajit S Puri, John Entwistle, Ramanathan Kadirvel, Harry J Cloft, David F Kallmes, Luis Savastano (2021) 'Quantification of clot spatial heterogeneity and its impact on thrombectomy'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2021) 'Association Between Clot Composition and Stroke Origin in Mechanical Thrombectomy Patients: Analysis of the Stroke Thromboembolism Registry of Imaging and Pathology'
Waleed Brinjikji, Raul G Nogueira, Peter Kvamme, Kennith F Layton, Josser E Delgado Almandoz, Ricardo A Hanel, Vitor Mendes Pereira, Mohammed A Almekhlafi, Albert J Yoo, Babak S Jahromi, Matthew J Gounis, Biraj Patel, Mehdi Abbasi, Seán Fitzgerald, Oana Madalina Mereuta, Daying Dai, Ramanathan Kadirvel, Karen Doyle, Luis Savastano, Harry J Cloft, Diogo C Haussen, Alhamza R Al-Bayati, Mahmoud H Mohammaden, Leonardo Pisani, Gabriel Martins Rodrigues, Ike C Thacker, Yasha Kayan, Alexander Copelan, Amin Aghaebrahim, Eric Sauvageau, Andrew M Demchuk, Parita Bhuva, Jazba Soomro, Pouya Nazari, Donald Robert Cantrell, Ajit S Puri, John Entwistle, Eric C Polley, David F Kallmes (2021) 'Association Between Clot Composition and Stroke Origin in Mechanical Thrombectomy Patients: Analysis of the Stroke Thromboembolism Registry of Imaging and Pathology'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2021) 'Per pass analysis of thrombus composition retrieved by mechanical thrombectomy'
Abbasi M, Kvamme P, Layton KF, Hanel RA, Almekhlafi MA, Delgado JE, Pereira VM, Patel BM, Jahromi BS, Yoo AJ, Nogueira RG, Gounis MJ, Fitzgerald S, Mereuta OM, Dai D, Kadirvel R, Kallmes DF, Doyle KM, Savastano LE, Cloft HJ, Liu Y, Thacker IC, Aghaebrahim A, Sauvageau E, Demchuk AM, Kayan Y, Copelan AZ, Entwistle J, Nazari P, Cantrell DR, Bhuva P, Soomro J, Haussen DC, Al-Bayati A, Mohammaden M, Pisani L, Rodrigues G, Puri AS, Brinjikji W. (2021) 'Per pass analysis of thrombus composition retrieved by mechanical thrombectomy'. Interventional Neuroradiology, [DOI] [Details]
(2021) 'Acute Ischemic Stroke: Correlation between Clot Length before Mechanical Thrombectomy and Extracted Clot Area: Impact of Thrombus Size on the Number of Passes for Clot Removal and Final Recanalization'
Rossi, Rosanna; Fitzgerald, Seán; Molina Gil, Sara; Mereuta, Oana; Douglas, Andrew; Pandit, Abhay; Brennan, Paul; Power, Sarah; Alderson, Jack; O'Hare, Alan; Gilvarry, Michael; McCarthy, Ray; Psychogios, Klearchos; Magoufis, George; Tsivgoulis, Georgios; Szikora, Istvan; Jood, Katarina; Redfors, Petra; Nordanstig, Annika; Ceder, Erik; Tatlisumak, Turgut; Rentzos, Alexandros; Thornton, John; Doyle, Karen (2021) 'Acute Ischemic Stroke: Correlation between Clot Length before Mechanical Thrombectomy and Extracted Clot Area: Impact of Thrombus Size on the Number of Passes for Clot Removal and Final Recanalization'. European Stroke Journal, [DOI] [ARAN Link] [Details]
(2021) 'Large Artery Atherosclerotic Clots Are Larger than Clots of Other Stroke Etiologies and have Poorer Reperfusion Rates'
Seán Fitzgerald, Rosanna Rossi, Duaa Jabrah, Adobi Okolo, Oana Madalina Mereuta, Sara Molina, Andrew Douglas, Abhay Pandit, Ray McCarthy, Michael Gilvarry, Lukas Holmegaard, Mikael Jerndal, Niclas Dehlfors, Georgios Tsivgoulis, Klearchos Psychogios, Paul Brennan, Sarah Power, Alan O¿Hare, Andras Nagy, Istvan Szikora, Turgut Tatlisumak, Alexandros Rentzos, John Thornton, Karen Doyle (2021) 'Large Artery Atherosclerotic Clots Are Larger than Clots of Other Stroke Etiologies and have Poorer Reperfusion Rates'. Journal Of Stroke & Cerebrovascular Diseases, [DOI] [Details]
(2021) 'The relationship between cerebral reperfusion and regional expression of matrix metalloproteinase-9 in rat brain following focal cerebral ischemia'
Douglas AS, Shearer JA, Okolo, A, Pandit A, Gilvarry M & Doyle KM (2021) 'The relationship between cerebral reperfusion and regional expression of matrix metalloproteinase-9 in rat brain following focal cerebral ischemia'. BMC Neuroscience, [DOI] [Details]
(2021) 'Per pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted-clot-area and histological composition'
Seán Fitzgerald, Rosanna Rossi, Oana Madalina Mereuta, Duaa Jabrah, Adaobi Okolo, Andrew Douglas, Sara Molina, Abhay Pandit, Ray McCarthy, Michael Gilvarry, Dennis Dunker, Annika Nordanstig, Erik Ceder, Petra Redfors, Katarina Jood, Niclas Dehlfors, Georgios Magoufis, Georgios Tsivgoulis, Waleed Brinjikji, David Kallmes, Alan O¿Hare, Sarah Power, Paul Brennan, Jack Alderson, András Nagy, Ágnes Vadász, Klearchos Psychogios, Istvan Szikora, Turgut Tatlisuma, Alexandros Rentzos, John Thornton, Karen Doyle (2021) 'Per pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted-clot-area and histological composition'. Journal Of Neurointerventional Surgery, [DOI] [ARAN Link] [Details]
(2021) 'High-resolution scanning electron microscopy for the analysis of 3D ultrastructure of clots in acute ischemic stroke'
Oana Madalina Mereuta, Seán Fitzgerald, Christensen A Trace, Jaspersen L Adam, Daying Dai, Mehdi Abbasi, Puttappa Tejaswini, Ramanathan Kadirvel, David F Kallmes, Karen Doyle, Waleed Brinjikji (2021) 'High-resolution scanning electron microscopy for the analysis of 3D ultrastructure of clots in acute ischemic stroke'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2021) 'The Administration of rtPA Before Mechanical Thrombectomy in Acute Ischemic Stroke patients is associated with a significant reduction of the retrieved clot area but it does not Influence Revascularization Outcome'
Rosanna Rossi, Seán Fitzgerald, Sara Molina, Oana Madalina Mereuta, Andrew Douglas, Abhay Pandit, Andreia M. Silva Santos, Blathnaid Murph, Jack Alderson, Paul Brennan, Sarah Power, Alan O¿Hare, Michael Gilvarry, Ray McCarthy, Klearchos Psychogios, Georgios Magoufis, Georgios Tsivgoulis, András Nagy, Ágnes Vadász, István Szikora, Katarina Jood, Petra Redfors, Annika Nordanstig, Erik Ceder, Niclas Dehlfors, Dennis Dunker, Turgut Tatlisumak, Alexandros Rentzos, John Thornton, Karen M. Doyle (2021) 'The Administration of rtPA Before Mechanical Thrombectomy in Acute Ischemic Stroke patients is associated with a significant reduction of the retrieved clot area but it does not Influence Revascularization Outcome'. Journal Of Thrombosis And Thrombolysis, [DOI] [Details]
(2021) 'Characterization of `white¿ clots in acute ischemic stroke'
Mereuta, Oana; Fitzgerald, Seàn ; Douglas, Andrew ; Rossi, Rosanna; Pandit, Abhay; McCarthy, Ray; Gilvarry, Michael; Brinjikji, Waleed; Kallmes, David; O'Hare, Alan; Power, Sarah; Brennan, Paul; Davidson, Maria; Brederlau, Anke; Allardt, Arne; Gunnarsson, Thorsteinn; Tatlisumak, Turgut; Rentzos, Alexandros; Thornton, John; Doyle, Karen (2021) 'Characterization of `white¿ clots in acute ischemic stroke'. Journal Of Stroke & Cerebrovascular Diseases, [DOI] [Details]
(2021) 'Embotrap Extraction & Clot Evaluation & Lesion Evaluation for NeuroThrombectomy EXCELLENT Registry Design and Methods'
Adnan H. Siddiqui; Muhammad Waqas; Waleed Brinjikji; Simon F. De Meyer; Karen Doyle; Jens Fiehler; Werner Hacke; Ricardo A. Hanel; Tudor Jovin; David S. Liebeskind; Albert J. Yoo; Osama O. Zaidat; Tommy Andersson; Raul G Nogueira (2021) 'Embotrap Extraction & Clot Evaluation & Lesion Evaluation for NeuroThrombectomy EXCELLENT Registry Design and Methods'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2021) 'Studying Stroke Thrombus Composition After Thrombectomy What Can We Learn?'
Senna Staessens , PhD; Olivier François, MD; Waleed Brinjikji, MD, PhD; Karen M. Doyle , PhD; Peter Vanacker, MD, PhD; Tommy Andersson , MD, PhD; Simon F. De Meyer , PhD (2021) 'Studying Stroke Thrombus Composition After Thrombectomy What Can We Learn?'. Stroke, [DOI] [ARAN Link] [Details]
(2021) 'Novel Human Acute Ischemic Stroke Blood Clot Analogs for In Vitro Thrombectomy Testing'
Fitzgerald, ST and Liu, Y and Dai, D and Mereuta, OM and Abbasi, M and Larco, JLA and Douglas, AS and Kallmes, DF and Savastano, L and Doyle, KM and others (2021) 'Novel Human Acute Ischemic Stroke Blood Clot Analogs for In Vitro Thrombectomy Testing'. American Journal of Neuroradiology, [ARAN Link] [Details]
(2021) 'Characterizing blood clots using acoustic radiation force optical coherence elastography and ultrasound shear wave elastography'
Liu, Hsiao-Chuan and Abbasi, Mehdi and Ding, Yong Hong and Roy, Tuhin and Capriotti, Margherita and Liu, Yang and Fitzgerald, Se\'an and Doyle, Karen M and Guddati, Murthy and Urban, Matthew W and others (2021) 'Characterizing blood clots using acoustic radiation force optical coherence elastography and ultrasound shear wave elastography'. Physics in Medicine \& Biology, 66 (3) [Details]
(2021) 'A novel rabbit thromboembolic occlusion model'
Ding, Yong-Hong and Fitzgerald, Se\'an and Liu, Yang and Dai, Daying and Jakaitis, Daniel and Doyle, Karen and Brinjikji, Waleed and Kallmes, David F and Savastano, Luis and Kadirvel, Ramanathan (2021) 'A novel rabbit thromboembolic occlusion model'. Journal of neurointerventional surgery, [Details]
(2021) 'Large Artery Atherosclerotic Clots are Larger than Clots of other Stroke Etiologies and have Poorer Recanalization rates'
Fitzgerald, S;Rossi, R;Mereuta, OM;Molina, S;Okolo, A;Douglas, A;Jabrah, D;Pandit, A;McCarthy, R;Gilvarry, M;Ceder, E;Dehlfors, N;Dunker, D;Nordanstig, A;Redfors, P;Jood, K;Magoufis, G;Psychogios, K;Tsivgoulis, G;Alderson, J;O'Hare, A;Power, S;Brennan, P;Nagy, A;Vadasz, A;Brinjikji, W;Kallmes, D;Szikora, I;Tatlisumak, T;Rentzos, A;Thornton, J;Doyle, KM (2021) 'Large Artery Atherosclerotic Clots are Larger than Clots of other Stroke Etiologies and have Poorer Recanalization rates'. Journal Of Stroke And Cerebrovascular Diseases : The Official Journal Of National Stroke Association, 30 [DOI] [Details]
(2021) 'A novel rabbit thromboembolic occlusion model'
Ding YH;Fitzgerald S;Liu Y;Dai D;Jakaitis D;Doyle K;Brinjikji W;Kallmes DF;Savastano L;Kadirvel R; (2021) 'A novel rabbit thromboembolic occlusion model'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2021) 'Characterizing blood clots using acoustic radiation force optical coherence elastography and ultrasound shear wave elastography'
Liu HC;Abbasi M;Ding YH;Roy T;Capriotti M;Liu Y;Fitzgerald S;Doyle KM;Guddati M;Urban MW;Brinjikji W; (2021) 'Characterizing blood clots using acoustic radiation force optical coherence elastography and ultrasound shear wave elastography'. Physics In Medicine And Biology, 66 (3) [DOI] [Details]
(2021) 'The Relationship Between Cerebral Reperfusion And Regional Expression Of Matrix Metalloproteinase-9 In Rat Brain Following Focal Cerebral Ischemia'
Douglas AS;Shearer JA;Okolo A;Pandit A;Gilvarry M;Doyle KM; (2021) 'The Relationship Between Cerebral Reperfusion And Regional Expression Of Matrix Metalloproteinase-9 In Rat Brain Following Focal Cerebral Ischemia'. Neuroscience, 453 [DOI] [Details]
(2020) 'High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke'
Mereuta, Oana Madalina and Fitzgerald, Se\'an and Christensen, Trace A and Jaspersen, Adam L and Dai, Daying and Abbasi, Mehdi and Puttappa, Tejaswini and Kadirvel, Ram and Kallmes, David F and Doyle, Karen M and others (2020) 'High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke'. Journal of NeuroInterventional Surgery, [Details]
(2020) 'Development of an in vitro model of calcified cerebral emboli in acute ischemic stroke for mechanical thrombectomy evaluation'
Johnson, Sarah and McCarthy, Ray and Fahy, Brian and Mereuta, Oana Madalina and Fitzgerald, Se\'an and Gaudirc, Julien and Remadi, Jean-Paul and Shotar, Eimad and Sourour, Nader-Antoine and Doyle, Karen and others (2020) 'Development of an in vitro model of calcified cerebral emboli in acute ischemic stroke for mechanical thrombectomy evaluation'. Journal of neurointerventional surgery, 12 (10):1002-1007 [Details]
(2020) 'High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke'
Mereuta, OM; Fitzgerald, S; Christensen, TA; Jaspersen AL; Dai, D; Abbasi, M; Puttappa, T; Kadirvel, R; Kallmes, DF; Doyle, KM; Brinjikji, W. (2020) 'High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke'. Journal Of Neurointerventional Surgery, [DOI] [ARAN Link] [Details]
(2020) 'High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke'
Mereuta OM;Fitzgerald S;Christensen TA;Jaspersen AL;Dai D;Abbasi M;Puttappa T;Kadirvel R;Kallmes DF;Doyle KM;Brinjikji W; (2020) 'High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2020) 'Clot permeability and histopathology: is a clot's perviousness on CT imaging correlated with its histologic composition?'
Benson, JC;Fitzgerald, ST;Kadirvel, R;Johnson, C;Dai, DY;Karen, D;Kallmes, DF;Brinjikji, W (2020) 'Clot permeability and histopathology: is a clot's perviousness on CT imaging correlated with its histologic composition?'. Journal Of Neurointerventional Surgery, 12 :38-42 [DOI] [Details]
(2020) 'Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition'
Fitzgerald S;Rossi R;Mereuta OM;Jabrah D;Okolo A;Douglas A;Molina Gil S;Pandit A;McCarthy R;Gilvarry M;Dunker D;Nordanstig A;Ceder E;Redfors P;Jood K;Dehlfors N;Magoufis G;Tsivgoulis G;Brinjikji W;Kallmes DF;O'Hare A;Power S;Brennan P;Alderson J;Nagy A;Vadász Á;Psychogios K;Szikora I;Tatlisumak T;Rentzos A;Thornton J;Doyle KM; (2020) 'Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition'. Journal Of Neurointerventional Surgery, [DOI] [Details]
(2020) 'The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does not influence revascularization outcome'
Rossi, R;Fitzgerald, S;Molina, S;Mereuta, OM;Douglas, A;Pandit, A;Santos, AMS;Murphy, B;Alderson, J;Brennan, P;Power, S;O'Hare, A;Gilvarry, M;McCarthy, R;Psychogios, K;Magoufis, G;Tsivgoulis, G;Nagy, A;Vadasz, A;Szikora, I;Jood, K;Redfors, P;Nordanstig, A;Ceder, E;Dehlfors, N;Dunker, D;Tatlisumak, T;Rentzos, A;Thornton, J;Doyle, KM (2020) 'The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does not influence revascularization outcome'. Journal Of Thrombosis And Thrombolysis, [DOI] [ARAN Link] [Details]
(2020) 'Storage of blood clots for histological analysis: how long is too long in saline and paraformaldehyde?'
Douglas, A;Fitzgerald, S;Pandit, A;Doyle, KM (2020) 'Storage of blood clots for histological analysis: how long is too long in saline and paraformaldehyde?'. Histology And Histopathology, 35 :313-320 [DOI] [Details]
(2020) 'Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes'
Douglas, A;Fitzgerald, S;Mereuta, OM;Rossi, R;O'Leary, S;Pandit, A;McCarthy, R;Gilvarry, M;Holmegaard, L;Abrahamsson, M;Jerndal, M;Dehlfors, N;Brennan, P;Power, S;O'Hare, A;Griffin, E;Kallmes, DF;Brinjikji, W;Szikora, I;Tatlisumak, T;Rentzos, A;Thornton, J;Doyle, K (2020) 'Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes'. Journal Of Neurointerventional Surgery, 12 :557-562 [DOI] [ARAN Link] [Details]
(2020) 'Development of an in vitro model of calcified cerebral emboli in acute ischemic stroke for mechanical thrombectomy evaluation'
Johnson S;McCarthy R;Fahy B;Mereuta OM;Fitzgerald S;Gaudirc J;Remadi JP;Shotar E;Sourour NA;Doyle K;Gilvarry M;McGarry P;McHugh PE;Clarençon F; (2020) 'Development of an in vitro model of calcified cerebral emboli in acute ischemic stroke for mechanical thrombectomy evaluation'. Journal Of Neurointerventional Surgery, 12 :1002-1007 [DOI] [Details]
(2020) 'Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure'
Santos, AMD,Gorman, AM,Kelly, JP,Doyle, KM (2020) 'Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure'. Neuroscience Letters, 715 [DOI] [Details]
(2019) 'Histological characterization of white clots retrieved by mechanical thrombectomy from acute ischemic stroke patients'
Mereuta, Oana Madalina and Fitzgerald, Se\'an and Douglas, Andy and Rossi, Rosanna and Silva Santos, Andreia M and Pandit, Abhay and Thornton, John and Rentzos, Alexandros and Tatlisumak, Turgut and Doyle, Karen M (2019) 'Histological characterization of white clots retrieved by mechanical thrombectomy from acute ischemic stroke patients'. BNA Festival of Neuroscience, [Details]
(2019) 'Clots retrieved by mechanical thrombectomy from acute ischemic stroke patients show no evidence of bacteria'
Khashim, Zenith and Fitzgerald, Se\'an and Kadirvel, Ramanathan and Dai, Daying and Doyle, Karen M and Brinjikji, Waleed and Kallmes, David F (2019) 'Clots retrieved by mechanical thrombectomy from acute ischemic stroke patients show no evidence of bacteria'. Interventional Neuroradiology, 25 (5):502-507 [Details]
(2019) 'Review of external referrals to a regional stroke centre: it is not just about thrombectomy'
Adams, NC;Griffin, E;Motyer, R;Farrell, T;Carmody, E;O'Shea, A;Murphy, B;O'Hare, A;Looby, S;Power, S;Brennan, P;Doyle, KM;Thornton, J (2019) 'Review of external referrals to a regional stroke centre: it is not just about thrombectomy'. Clinical Radiology, 74 :950-955 [DOI] [Details]
(2019) 'Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots'
Fitzgerald, S;Wang, SL;Dai, DY;Murphree, DH;Pandit, A;Douglas, A;Rizvi, A;Kadirvel, R;Gilvarry, M;McCarthy, R;Stritt, M;Gounis, MJ;Brinjikji, W;Kallmes, DF;Doyle, KM (2019) 'Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots'. Plos One, 14 [DOI] [ARAN Link] [Details]
(2019) 'Histological stroke clot analysis after thrombectomy: Technical aspects and recommendations'
Staessens, S;Fitzgerald, S;Andersson, T;Clarencon, F;Denorme, F;Gounis, M;Hacke, W;Liebeskind, DS;Szikora, I;van Es, ACGM;Brinjikji, W;Doyle, KM;Meyer, SF (2019) 'Histological stroke clot analysis after thrombectomy: Technical aspects and recommendations'. International Journal Of Stroke, [DOI] [ARAN Link] [Details]
(2019) 'Clots retrieved by mechanical thrombectomy from acute ischemic stroke patients show no evidence of bacteria'
Khashim, Z;Fitzgerald, S;Kadirvel, R;Dai, D;Doyle, KM;Brinjikji, W;Kallmes, DF (2019) 'Clots retrieved by mechanical thrombectomy from acute ischemic stroke patients show no evidence of bacteria'. Interventional Neuroradiology, 25 :502-507 [DOI] [Details]
(2019) 'Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome'
Fitzgerald, S;Mereuta, OM;Doyle, KM;Dai, DY;Kadirvel, R;Kallmes, DF;Brinjikji, W (2019) 'Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome'. JOURNAL OF NEUROSURGICAL SCIENCES, 63 :292-300 [DOI] [Details]
(2019) 'A Standardized Aspiration-First Approach for Thrombectomy to Increase Speed and Improve Recanalization Rates'
O'Neill, D,Griffin, E,Doyle, KM,Power, S,Brennan, P,Sheehan, M,O'Hare, A,Looby, S,Santos, AMD,Rossi, R,Thornton, J (2019) 'A Standardized Aspiration-First Approach for Thrombectomy to Increase Speed and Improve Recanalization Rates'. American Journal Of Neuroradiology, 40 :1335-1341 [DOI] [ARAN Link] [Details]
(2019) 'Acute ischemic stroke secondary to cardiac embolus of a 'foreign body' material after a redo sternotomy for mitral valve replacement: A case report'
Fitzgerald, S,Rizvi, A,Dai, DY,Williamson, EE,Lanzino, G,Doyle, KM,Kalimes, DF,Brinjikji, W (2019) 'Acute ischemic stroke secondary to cardiac embolus of a 'foreign body' material after a redo sternotomy for mitral valve replacement: A case report'. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 25 :208-211 [DOI] [Details]
(2019) 'Effect of a binge-like dosing regimen of methamphetamine on dopamine levels and tyrosine hydroxylase expressing neurons in the rat brain'
Santos, AMD,Kelly, JP,Dockery, P,Doyle, KM (2019) 'Effect of a binge-like dosing regimen of methamphetamine on dopamine levels and tyrosine hydroxylase expressing neurons in the rat brain'. Progress In Neuro-Psychopharmacology & Biological Psychiatry, 89 :303-309 [DOI] [ARAN Link] [Details]
(2019) 'Platelet-Rich Emboli in Cerebral Large Vessel Occlusion Are Associated With a Large Artery Atherosclerosis Source'
Fitzgerald, S;Dai, DY;Wang, SL;Douglas, A;Kadirvel, R;Layton, KF;Thacker, IC;Gounis, MJ;Chueh, JY;Puri, AS;Almekhlafi, M;Demchuk, AM;Hanel, RA;Sauvageau, E;Aghaebrahim, A;Yoo, AJ;Kvamme, P;Pereira, VM;Kayan, Y;Almandoz, JED;Nogueira, RG;Rabinstein, AA;Kallmes, DF;Doyle, KM;Brinjikji, W (2019) 'Platelet-Rich Emboli in Cerebral Large Vessel Occlusion Are Associated With a Large Artery Atherosclerosis Source'. Stroke, 50 :1907-1910 [DOI] [Details]
(2019) 'Storage of blood clots for histological analysis: How long is too long in saline and paraformaldehyde?'
Douglas, Andrew and Fitzgerald, Se\'an and Pandit, Abhay and Doyle, Karen M (2019) 'Storage of blood clots for histological analysis: How long is too long in saline and paraformaldehyde?'. Histology and histopathology, [Details]
(2018) 'Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome'
Fitzgerald, Se\'an and Mereuta, Oana M and Doyle, Karen M and Kadirvel, R and Kallmes, DF and Brinjikji, W and others (2018) 'Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome'. Journal of neurosurgical sciences, 63 (3):292-300 [Details]
(2017) 'Effect of mechanical reperfusion outcome on the expression of matrix metalloproteinase-9 (MMP-9) in rat brain following an acute occlusive stroke'
Shearer, J. and Douglas, A. and Pandit, A. and Doyle, K. (2017) 'Effect of mechanical reperfusion outcome on the expression of matrix metalloproteinase-9 (MMP-9) in rat brain following an acute occlusive stroke'. Journal of Cerebral Blood Flow and Metabolism, 37 [Details]
(2017) 'HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis'
Kennedy, D,Mnich, K,Oommen, D,Chakravarthy, R,Almeida-Souza, L,Krols, M,Saveljeva, S,Doyle, K,Gupta, S,Timmerman, V,Janssens, S,Gorman, AM,Samali, A (2017) 'HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis'. Cell Death & Disease, 8 [DOI] [Details]
(2017) 'Dose-Dependent Effects of Binge-Like Methamphetamine Dosing on Dopamine and Neurotrophin Levels in Rat Brain'
Santos, AMD,Kelly, JP,Doyle, KM (2017) 'Dose-Dependent Effects of Binge-Like Methamphetamine Dosing on Dopamine and Neurotrophin Levels in Rat Brain'. Neuropsychobiology, 75 :63-71 [DOI] [Details]
(2017) 'Animal models of focal cerebral ischaemia and haemorrhage transformation: considerations in experimental stroke study design'
Shearer, JA, Douglas, AS, Kirby BP, Tatlisumak T & Doyle KM (2017) 'Animal models of focal cerebral ischaemia and haemorrhage transformation: considerations in experimental stroke study design'. Current Vascular Pharmacology, [ARAN Link] [Details]
(2016) 'Effect of N1-Dansylspermine and Ro25,6981 on locomotor activity in naive mice and in the resperpinised mouse model of Parkinson's Disease'
Devadasan, C, Starr, B & Doyle KM (2016) 'Effect of N1-Dansylspermine and Ro25,6981 on locomotor activity in naive mice and in the resperpinised mouse model of Parkinson's Disease'. Neuroreport, 27 (17):1243-1247 [ARAN Link] [Details]
(2015) 'Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation'
Bailey, D,Kirby, BP,Atkinson, J,Fixon-Owoo, S,Henman, MC,Shaw, GG,Doyle, KM (2015) 'Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation'. Pharmacology Biochemistry And Behavior, 133 :57-64 [DOI] [ARAN Link] [Details]
(2014) 'Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner'
Mnich, K,Carleton, LA,Kavanagh, ET,Doyle, KM,Samali, A,Gorman, AM (2014) 'Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner'. Cell Death & Disease, 5 [DOI] [ARAN Link] [Details]
(2012) 'Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase'
Butler, RK;Ford, GK;Hogan, M;Roche, M;Doyle, KM;Kelly, JP;Kendall, DA;Chapman, V;Finn, DP (2012) 'Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase'. Journal Of Psychopharmacology, 26 :83-91 [DOI] [ARAN Link] [Details]
(2011) 'Recent Advances in Psychoneuroimmunology: Inflammation in Psychiatric Disorders'
Debnath, M,Doyle, KM,Langan, C,McDonald, C,Leonard, B,Cannon, DM (2011) 'Recent Advances in Psychoneuroimmunology: Inflammation in Psychiatric Disorders'. Translational Neuroscience, 2 (2):121-137 [DOI] [Details]
(2011) 'Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders'
Doyle KM, Kennedy D, Gorman AM, Gupta S, Healy SJ, Samali A (2011) 'Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders'. Journal Of Cellular And Molecular Medicine, [Details]
(2009) 'Serum BDNF levels in euthymic bipolar disorder: preliminary results from the Galway Bipolar Study'
Langan, C.,Doyle, K.,Kelly, J.,Emsell, L.,Skinner, R.,McDonald, C. (2009) 'Serum BDNF levels in euthymic bipolar disorder: preliminary results from the Galway Bipolar Study'. Bipolar Disorders, 11 :56-56 [Details]
(2009) 'Analysis of cellular environment of spinal cord lesion following transplantation of neural stem cells into injured rat spinal cord'
Hynes, J.,Bourke, E.,Deering, E. M.,Doherty, G.,Murray, A.,Dockery, P.,Doyle, K.,Gorman, A.,Barry, F. P.,McMahon, S. S. (2009) 'Analysis of cellular environment of spinal cord lesion following transplantation of neural stem cells into injured rat spinal cord'. Journal of Anatomy, 214 (55):793-793 [Details]
(2009) 'Considerations and recent advances in neuroscience'
Gorman, A. M.,Doyle, K. M. (2009) 'Considerations and recent advances in neuroscience'. Biochemical Society Transactions, 37 :299-302 [Details]
(2007) 'Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia'
Li J, Doyle, K.M. & Tatlisumak T (2007) 'Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia'. Curr Med Chem, 14 (17):1807-1813 [ARAN Link] [Details]
(2006) 'The pre-ischaemic neuroprotective effects of the polyamine analogues BU43b and BU36b in permanent and transient focal cerebral ischaemia models in mice'
Li, J;Henman, MC;Atkinson, J;Fixon-Owoo, S;Tatlisumak, T;Shaw, GG;Doyle, KM (2006) 'The pre-ischaemic neuroprotective effects of the polyamine analogues BU43b and BU36b in permanent and transient focal cerebral ischaemia models in mice'. Brain Research, 1076 :209-215 [DOI] [Details]
(2006) 'Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine'
Kavanagh, ET,Loughlin, JP,Herbert, KR,Dockery, P,Samall, A,Doyle, KM,Gorman, AM (2006) 'Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine'. Biochemical And Biophysical Research Communications, 351 :890-895 [DOI] [Details]
(2006) 'The pre-ischaemic neuroprotective effects of the polyamine analogues BU43b and BU36b in permanent and transient focal cerebral ischaemia models in mice'
Li, J,Henman, MC,Atkinson, J,Fixon-Owoo, S,Tatlisumak, T,Shaw, GG,Doyle, KM (2006) 'The pre-ischaemic neuroprotective effects of the polyamine analogues BU43b and BU36b in permanent and transient focal cerebral ischaemia models in mice'. Brain Research, 1076 :209-215 [DOI] [Details]
(2005) 'Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo'
Doyle, KM;Kirby, BP;Murphy, D;Shaw, GG (2005) 'Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo'. Neuroscience Letters, 380 :247-251 [DOI] [Details]
(2004) 'The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N-1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice'
Li, J;Henman, MC;Doyle, KM;Strbian, D;Kirby, BP;Tatlisumak, T;Shaw, GG (2004) 'The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N-1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice'. Brain Research, 1029 :84-92 [DOI] [Details]
(2004) 'Preliminary characterisation of an in vitro paradigm for the study of the delayed effects of organophosphorus compounds: hen embryo brain spheroids'
Sales, KM;Kingston, ST;Doyle, KM;Purcell, WM (2004) 'Preliminary characterisation of an in vitro paradigm for the study of the delayed effects of organophosphorus compounds: hen embryo brain spheroids'. Toxicology, 195 :187-202 [DOI] [Details]
(1998) 'Investigation of the actions and antagonist activity of some polyamine analogues in vivo'
Doyle, K.M.,Shaw, G.G. (1998) 'Investigation of the actions and antagonist activity of some polyamine analogues in vivo'. British Journal Of Pharmacology, 124 :386-390 [Details]
(1998) 'Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour'
Doyle, K.M., Feerick, S., Kirkby, D.L., Eddleston, A. & Higgins, G.A. (1998) 'Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour'. Behavioural Pharmacology, 9 :671-681 [Details]
(1996) 'Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo'
Doyle, K.M. : Shaw, G.G. (1996) 'Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo'. British Journal Of Pharmacology, 117 :1803-1808 [Details]
(1996) 'Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex'
Purcell, W.M., Doyle, K.M., Westgate, C. : Atterwill, C.K (1996) 'Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex'. Journal Of Neuroimmunology, 65 :49-53 [Details]
(1994) 'Histamine release from mast cells by polyamines: an NMDA receptor-mediated event?'
Purcell, W.M., Doyle, K.M., Bagga, L. : Derks, M. (1994) 'Histamine release from mast cells by polyamines: an NMDA receptor-mediated event?'. Biochemical Society Transactions, 22 [Details]
(1994) 'The mechanism of the neurotoxic effects of spermidine'
Doyle, K.M.,Shaw, G.G. (1994) 'The mechanism of the neurotoxic effects of spermidine'. Biochemical Society Transactions, 22 [Details]

Conference Publications

  Year Publication
(2021) International Stroke Conference
Raul G Nogueira; Adnan H. Siddiqui; Simon F. De Meyer; Karen Doyle; Jens Fiehler; Werner Hacke; Ricardo A. Hanel; Tudor Jovin; Waleed Brinjikji; David S. Liebeskind; Albert J. Yoo; Osama O. Zaidat; Diogo Haussen; Violiza Inoa; William Humphries; Keith B. Woodward; Pascal M. Jabbour; Olivier Francois; Shervin R. Dashti; Hormozd Bozorgchami; Elad I. Levy; Ronald F. Budzik; Clemens M. Schirmer; Muhammad A. Taqi; Reade A. De Leacy; Stephan Boor; M. Shazam Hussain; Ajit S. Puri; Laurent Estrade; Tommy Andersson (2021) Clot Characteristics in Mechanical Thrombectomy: Interim Analysis of the EXCELLENT Registry International Stroke Conference [Details]
(2021) International Stroke Conference
Raul G Nogueira; Adnan H. Siddiqui; Simon F. De Meyer; Karen Doyle; Jens Fiehler; Werner Hacke; Ricardo A. Hanel; Tudor Jovin; Waleed Brinjikji; David S. Liebeskind; Albert J. Yoo; Osama O. Zaidat; Diogo Haussen; Violiza Inoa; William Humphries; Keith B. Woodward; Pascal M. Jabbour; Olivier Francois; Shervin R. Dashti; Hormozd Bozorgchami; Elad I. Levy; Ronald F. Budzik; Clemens M. Schirmer; Muhammad A. Taqi; Reade A. De Leacy; Stephan Boor; M. Shazam Hussain; Ajit S. Puri; Laurent Estrade; Tommy Andersson (2021) 1. Clot Characteristics in Mechanical Thrombectomy: Interim Analysis of the EXCELLENT Registry International Stroke Conference [Details]
(2021) International Stroke Conference
Raul G Nogueira; Adnan H. Siddiqui; Simon F. De Meyer; Karen Doyle; Jens Fiehler; Werner Hacke; Ricardo A. Hanel; Tudor Jovin; Waleed Brinjikji; David S. Liebeskind; Albert J. Yoo; Osama O. Zaidat; Diogo Haussen; Violiza Inoa; William Humphries; Keith B. Woodward; Pascal M. Jabbour; Olivier Francois; Shervin R. Dashti; Hormozd Bozorgchami; Elad I. Levy; Ronald F. Budzik; Clemens M. Schirmer; Muhammad A. Taqi; Reade A. De Leacy; Stephan Boor; M. Shazam Hussain; Ajit S. Puri; Laurent Estrade; Tommy Andersson (2021) 1. Clot Characteristics in Mechanical Thrombectomy: Interim Analysis of the EXCELLENT Registry International Stroke Conference [Details]
(2021) International Stroke Conference
Raul G Nogueira; Adnan H. Siddiqui; Simon F. De Meyer; Karen Doyle; Jens Fiehler; Werner Hacke; Ricardo A. Hanel; Tudor Jovin; Waleed Brinjikji; David S. Liebeskind; Albert J. Yoo; Osama O. Zaidat; Diogo Haussen; Violiza Inoa; William Humphries; Keith B. Woodward; Pascal M. Jabbour; Olivier Francois; Shervin R. Dashti; Hormozd Bozorgchami; Elad I. Levy; Ronald F. Budzik; Clemens M. Schirmer; Muhammad A. Taqi; Reade A. De Leacy; Stephan Boor; M. Shazam Hussain; Ajit S. Puri; Laurent Estrade; Tommy Andersson (2021) 1. Clot Characteristics in Mechanical Thrombectomy: Interim Analysis of the EXCELLENT Registry International Stroke Conference [Details]
(2020) 2020 42nd Annual International Conference of the IEEE Engineering in Medicine \& Biology Society (EMBC)
Santorelli, Adam and Fitzgerald, Se\'an and Douglas, Andrew and Doyle, Karen and O’Halloran, Martin (2020) Dielectric profile of blood clots to inform ischemic stroke treatments 2020 42nd Annual International Conference of the IEEE Engineering in Medicine \& Biology Society (EMBC) , pp.3723-3726 [Details]
(2020) STROKE
Liu, Hsiao-Chuan and Fitzgerald, Sean and Rizvi, Asim and Caracena, Thomas and Doyle, Karen M and Kadirvel, Ramanathan and Kallmes, David F and Brinjikji, Waleed and Urban, Matthew W (2020) Evaluating Mechanical Properties of Human Blood Clot Analogues Using Ultrasound-mediated Optical Coherence Elastography STROKE [Details]
(2020) EMBC 2020 Montreal
Adam Santorelli, Sean Fitzgerald, Andrew Douglas, Karen M. Doyle & Martin O’Halloran (2020) Dielectric profile of blood clots to inform ischemic stroke treatments EMBC 2020 Montreal [DOI] [ARAN Link] [Details]
(2019) BNA 2019 Festival of Neuroscience
Okolo, A; Shearer, J; Prendergast, J; Douglas, A; McMahon, J; Fitzgerald, U; Doyle, K (2019) Change in ATF6 and CHOP expression in the brain following ischemic stroke and reperfusion BNA 2019 Festival of Neuroscience Dublin, Ireland, , 14-APR-19 - 17-APR-19 [Details]
(2019) European Stroke Organisation Conference 2019
Douglas, A; Fitzgerald, S; Rentzos, A; Thornton, J; Tatlisumak, T; Pandit, A; Silva Santos, A; Rossi, R; Mereuta, OM; Doyle, K (2019) Platelets and von Willebrand factor are key components in acute ischemic stroke clots European Stroke Organisation Conference 2019 [Details]
(2019) ESOC, European Stroke Organisation Conference
Silva Santos, AM; Rossi R; Pandit, A; Fitzgerald, S; Mereuta, OM; Douglas, A; Thornton, J; Brennan, P; Power, S; O’ Hare, A; Rentzos, A; Ceder, E; Tatlisumak, T; Jood, K; Redfors, P; Nordanstig, A; Duffy, S; Gilvarry, M; McCarthy, R; Doyle, KM. (2019) ESOC Abstracts Supplement 2019 ESOC, European Stroke Organisation Conference [ARAN Link] [Details]
(2019) WFITN, World Federation of Interventional and Therapeutic Neuroradiology Congress
Rossi, R; Fitzgerald, S; Mereuta, OM; Douglas, A; Pandit, A; Szikora, I; Tsivgoulis, G; Psychogios, K; Murphy, B; Brennan, P; Power, S; O'Hare, A; Thornton, J; Rentzos, A; Tatlisumak, T; Doyle, KM (2019) The impact of occlusion location and bridging therapy in patients affected by Acute Ischemic Stroke in determining the total number of passes required to remove the clot and the final revascularization outcome WFITN, World Federation of Interventional and Therapeutic Neuroradiology Congress [ARAN Link] [Details]
(2019) 5th European Stroke Organisation Conference (ESOC)
Mereuta, OM; Fitzgerald, S; Douglas, A; Rossi, R; Silva Santos, AM; Pandit, A; Thornton, J; O'Hare, A; Power, S; Brennan, P; Rentzos, A; Tatlisumak, T; Gunnarsson, T; Davidson, M; Brederlau, A; Allardt, A; Brinjikji, W; Kallmes, DF; Doyle, KM (2019) Fatty acid binding protein expression in clots retrieved by mechanical thrombectomy from patients with acute ischaemic stroke . In: European Stroke Journal 2019 (volume 4, 1S) eds. 5th European Stroke Organisation Conference (ESOC) , pp.3-95 [DOI] [ARAN Link] [Details]
(2019) BNA Festival of Neuroscience
Mereuta, OM; Fitzgerald, S; Douglas, A; Rossi, R; Silva Santos, AM; Pandit, A; Thornton, J; Rentzos, A; Tatlisumak, T; Doyle, KM (2019) Histological characterization of ‘white’ clots retrieved by mechanical thrombectomy from acute ischemic stroke patients . In: Brain and Neuroscience Advances Journal 2019 (volume 3) eds. BNA Festival of Neuroscience [DOI] [ARAN Link] [Details]
(2019) British Neuroscience Association
Prendergast, J., Okolo, A., Douglas, A., Shearer, J., Roche, M. and Doyle, K. (2019) Cyclooxygenase-2 Expression in the Brain Following Ischemic Stroke and its Effects on Glial Cells British Neuroscience Association [Details]
(2019) British Neuroscience Association
Adaobi Okolo; J. Shearer; J. Prendergast; A. Douglas; U. Fitzgerald; Doyle, KM (2019) Change in ATF6 expression in the brain, following ischemic stroke and reperfusion British Neuroscience Association [Details]
(2019) International Stroke Conference
1. Michel Muster; Sean Fitzgerald; Doyle, KM; K. Lövblad (2019) MicroCT data can distinguish between in vitro clot types of different composition International Stroke Conference [Details]
(2018) European Stroke Organisation Conference 2018
Douglas, AD; Shearer, J; Pandit, A; Doyle, K (2018) THE EFFECT OF MECHANICAL REPERFUSION OUTCOME FOLLOWING AN OCCLUSIVE STROKE ON THE REGIONAL EXPRESSION OF MATRIX METALLOPROTEINASE-9 IN RAT BRAIN European Stroke Organisation Conference 2018 [Details]
(2018) International Stroke Conference
Fitzgerald, S and Rizvi, A and Michalak, G and Kadirvel, R and Doyle, K and Brinjikji, W and Kallmes, D (2018) P-024 Dual-energy CT-based characterization of experimental human clot analogues with different compositions created under dynamic flow conditions: an in vitro stroke study International Stroke Conference [Details]
(2018) Society of Neurointerventional Surgery
Seán Fitzgerald; Asim Rizvi; Gregory Michalak; Ramanathan Kadirvel; Doyle, Karen M.; Waleed Brinjikji; David F. Kallmes (2018) Dual-energy CT-based Characterization of Experimental Human Clot Analogues with Different Compositions Created Under Dynamic Flow Conditions: An In Vitro Stroke Study Society of Neurointerventional Surgery [Details]
(2018) World Congress of Biomechanics
Seán Fitzgerald; Shunli Wang; Daying Dai; Abhay Pandit; Andrew Douglas; Ramanathan Kadirvel; Waleed Brinjikji; David F. Kallmes; Doyle, Karen M. (2018) Identification of platelet rich clots following mechanical thrombectomy may identify patients who would benefit from anti-platelet therapy to prevent a recurrent ischaemic stroke World Congress of Biomechanics [Details]
(2018) European Stroke Organisation Conference
Andrew Douglas; Sean Fitzgerald; Abhay Pandit; Doyle, Karen M. (2018) Storage of blood clots for histological analysis: how long is too long in saline and formalin? European Stroke Organisation Conference [Details]
(2018) European Stroke Organisation Conference
Jennifer Shearer; Andrew Douglas; Abhay Pandit; Doyle, Karen M. (2018) The effect of mechanical reperfusion outcome following an occlusive stroke on the regional expression of matrix metalloproteinase-9 in rat brain European Stroke Organisation Conference [Details]
(2018) European Stroke Organisation Conference
Seán Fitzgerald; Daying Dai; Shunli Wang; Abhay Pandit; Andrew Douglas; Ramanathan Kadirvel; Matthew J. Gounis; Waleed Brinjikji; David F. Kallmes; Doyle Karen M. (2018) Initial findings from the CURAM and Mayo Clinic International Acute Ischaemic Stroke clot registry European Stroke Organisation Conference [Details]
(2018) International Stroke conference
Seán Fitzgerald; Shunli Wang; Daying Dai; Andrew Douglas; Ramanathan Kadirvel; Waleed Brinjikji; David F. Kallmes; Doyle, Karen M. (2018) Machine-Learned Characterization of Acute Ischemic Stroke Clots reveals a Correlation between Clot Composition and Density on CT International Stroke conference [Details]
(2017) 28th International Symposium on Cerebral Blood Flow, Metabolism & Function
Shearer, J; Douglas, A; Pandit, A; Doyle, KM (2017) Effect of mechanical reperfusion outcome on the expression of matrix metalloproteinase-9 in rat brain following an acute occlusive stroke 28th International Symposium on Cerebral Blood Flow, Metabolism & Function [Details]
(2017) Effect of mechanical reperfusion outcome on the expression of matrix metalloproteinase-9 (MMP-9) in rat brain following an acute occlusive stroke
Shearer, J; Douglas, A; Pandit, A; Doyle, K (2017) JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM Effect of mechanical reperfusion outcome on the expression of matrix metalloproteinase-9 (MMP-9) in rat brain following an acute occlusive stroke , pp.440-440 [Details]
(2016) The Physiological Society
Shearer, JA; Douglas, AS; Kirby BP; Pandit A; Doyle KM (2016) The relationship between cerebral reperfusion after an occlusive stroke and the development of haemorrhage transformation in otherwise healthy rats The Physiological Society The Physiological Society Transactions ID: 2531424, [DOI] [Details]
(2010) METHAMPHETAMINE EFFECTS ON CELL VIABILITY, BDNF LEVELS AND NEURITE OUTGROWTH IN PC12 CELLS
Santos, AM,Kelly, JP,Doyle, KM (2010) IRISH JOURNAL OF MEDICAL SCIENCE METHAMPHETAMINE EFFECTS ON CELL VIABILITY, BDNF LEVELS AND NEURITE OUTGROWTH IN PC12 CELLS , pp.139-139 [Details]
(2009) BIOCHEMICAL SOCIETY TRANSACTIONS
Gorman, AM;Doyle, KM (2009) Considerations and recent advances in neuroscience BIOCHEMICAL SOCIETY TRANSACTIONS , pp.299-302 [DOI] [Details]
(2003) Investigation of the antagonist action of novel polyamine analogues on spermine induced CNS excitation in mice in vivo
Murphy, DH,Shaw, GG,Atkinson, J,Fixon-Owoo, S,Henman, M,Doyle, KM (2003) BRITISH JOURNAL OF PHARMACOLOGY Investigation of the antagonist action of novel polyamine analogues on spermine induced CNS excitation in mice in vivo [Details]
(2002) Protein expression in rat liver: Response to short term treatment with phenobarbital using two-dimensional gel electrophoresis
Pantasri, P,Rapley, R,Hoffman, R,Walker, JM,Lord, PG,Skehel, MJ,Kramer, K,Doyle, KM (2002) BRITISH JOURNAL OF PHARMACOLOGY Protein expression in rat liver: Response to short term treatment with phenobarbital using two-dimensional gel electrophoresis [Details]
(2001) The effect of the co-administration of eliprodil with memantine in naive and reserpinised mice
Devadasan, C,Starr, BS,Doyle, KM (2001) BRITISH JOURNAL OF PHARMACOLOGY The effect of the co-administration of eliprodil with memantine in naive and reserpinised mice [Details]

Other Journals

  Year Publication
(2021) 'Time is of the essence: New developments in Acute Ischaemic Stroke Treatment'
Rossi R, Douglas A, Tierney C, Doyle K (2021) 'Time is of the essence: New developments in Acute Ischaemic Stroke Treatment' Physiology News, . [Details]
(2020) 'Book Review: How to live in space by Colin Stewart'
Doyle KM (2020) 'Book Review: How to live in space by Colin Stewart' Physiology News, (117) :15-16. [DOI] [Details]
(2016) 'Physiology at NUI Galway'
M Kane, K Doyle & T Wheatley (2016) 'Physiology at NUI Galway' Physiology News, (104) :12-14. [Details]
(2016) 'Editorial'
K Doyle (2016) 'Editorial' Physiology News, (104) :5-5. [Details]

Honours and Awards

  Year Title Awarding Body
2015 Presidents Award for Teaching Excellence NUI Galway
2015 National Teaching Experts Award National Forum for the Enhancement of Teaching and Learning in Higher Education (in Ireland)

Professional Associations

  Association Function From / To
Neuroscience Ireland President 01-SEP-21 /
Federation of Neuroscience Societies Member of FENS Governing Council 01-SEP-21 /
International Brain Research Organisation Member of IBRO Governing Council 01-SEP-21 /
European Stroke Organisation Member of ESO Membership Committee 01-SEP-19 /
World Stroke Organisation Member 29-NOV-17 /
The Physiological Society Ordinary Member 2002 /

Committees

  Committee Function From / To
Neuroscience Ireland Council Chair 01-SEP-21 /
FENS Governing Council National representative 01-SEP-21 /
IBRO Governing Council National representative 01-SEP-21 /
CURAM Executive Committee Member 30-OCT-19 /
Strategic Development Group Member of committee and member of the Editing subgroup 28-NOV-18 /
Academic Council Member 03-SEP-18 /
Neuroscience Ireland Executive Member 01-JAN-07 / 31-DEC-09
University Ethics Committee Member 01-JAN-06 / 31-DEC-09
Galway Neuroscience Centre Founder member. Group Leader (2004 - 2009) 01-JAN-04 /
Graduate Studies Board Vice Dean for Graduate Studies, College of Medicine Nursing & Health Sciences 01-JAN-11 / 31-DEC-15

Education

  Year Institution Qualification Subject
1989 University College Dublin BSc (Hons) Pharmacology
1994 Trinity College Dublin PhD Neuroscience
2016 NUI Galway Higher Diploma Academic Practice

Community Engagement

  Title Type From / To
Outreach Neuroscience at the Science Festival 01-NOV-14 / 01-JAN-18
Outreach A Tiny Spark 01-DEC-18 /
Outreach Brain Awareness Week 16-MAR-09 / 01-JAN-19

Reviews

  Journal Role
Frontiers In Neurology Series Editor
Plos One Editor
Brain Research Reviewer
Stroke Reviewer
Journal Of Neurointerventional Surgery Reviewer
Journal Of Neuroscience Research Reviewer
Scientific reports Reviewer
Journal Of Cellular And Molecular Medicine Reviewer
European Psychiatry Reviewer
Neuroscience Letters Reviewer

Other Activities

  Description

Member of Conference Organising Committee, British Neuroscience Association Festival of Neuroscience 2023, Brighton

Neuroscience Ireland conference local organising committee lead organiser 2008 2017

Appointed a member of the Iontas Alliance (2017); A forum of National Awardees of Teaching Excellence in Higher Education in Ireland, for the enhancement of Teaching and Learning nationally and showcasing the Higher Education sector internationally

Teaching Interests

Neurophysiology
Central Nervous System
Advanced Neurophysiology
Scientific Writing and Communication

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2009 Edel Kavanagh PhD
2001 Carol Devadasan PhD Y
2004 Prayed Pantasri PhD
1999 Kevin Sales PhD
2004 John Loughlin Msc
2005 Jun Li PhD
2006 Desiree Murphy PhD
2012 Geraldine Lavelle Msc
2010 Andreia Moreira Da Silva Santos PhD Y
2010 Camilla Langan PhD
2014 Donna Kennedy PhD
2008 Sarath Kiran Msc Y

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
1/2022 Neurophysiology SI311/ SI209
1/2022 Advanced Neurophysiology SI422
1/2022 Scientific Communication SI4102
1/2022 Central Nervous System MD224

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Prof Turgut Tatlisumak University of Gothenburg SWEDEN
Stroke research
Prof John Thornton Beaumont Hospital Dublin IRELAND
Prof Istvan Szikora National Institute of Clinical Neuroscience HUNGARY
Dr Alexandros Rentzos Sahlgrenska Hospital, Gothenburg SWEDEN
Prof Simon De Meyer KU Leuven BELGIUM
Stroke Clot Research
Dr Waleed Brinjikji Mayo Clinic U.S.A.
Prof David Kallmes Mayo Clinic U.S.A.
Stroke Clot Research