Dr Ananya Gupta

Ph.D

Contact Details

Lecturer Above the Bar
Human Biology Building
NUI Galway
T: 091-492358
E: ananya.gupta@nuigalway.ie
 
researcher
 

Biography

Education  
1992- 1995   Bachelor of Science (B. Sc) in Physiology, First class (Hons) Presidency College, Calcutta University, India
1995- 1997   Master of Science (M. Sc) in Biophysics and Molecular Biology (With Subjects including: Molecular Biology, Biochemistry, Microbiology, Immunology, Biophysics, Biostatistics and Genetics). Calcutta University, India
1998-2005    Ph.D in Life Sciences (Host-Pathogen Interaction and Immunology) Thesis Title: Identification and characterization of different cell death pathways in Leishmania Donovani. Centre for Cellular and Molecular Biology, Hyderabad. Jawaharlal Nehru University, New Delhi, India
2016-2018   Teaching Qualification (Centre for Excellence in Learning and Teaching (CELT) NUI Galway)
Postgraduate Certificate in Teaching and Learning in Higher Education
Postgraduate Diploma in Academic Practice
  
Current Position
Lecturer (Above the Bar) in Discipline of Physiology (January 2016-Present)
Academic Director for MSc in Exercise Physiology and its Application in Therapy

Research Interests

Research Interests:
  • Molecular mechanisms in Cancer progression
  • miRNAs as biomarkers in Cancer prognosis and response to therapy
  • Management and prevention of chemotherapy induced toxicity in Cancer treatment
  • Exercise as Therapy and its Application in Cancer rehabilitation
  • Exercise interventions in training and sports performance

My Research is particularly aligned with the University’s research priority themes of cancer treatment, stem cell derived therapeutics and biomedical devices.  

My Research is also translational, multidisciplinary and collaborative. 

Current research projects -
  • Isolation, Expansion and Differentiation of UCB derived HSC into functional Neutrophils for transfusion
  • Detection and monitoring of chemotherapy induced Neutropenia in cancer patients using a near patient hand held biomedical device
  • Implementing a community based program in aerobic exercise and resistance training to improve recovery following cancer treatment
  • Identification of sports specific physiologic predictors of performance
  • Role of unfolded signalling pathway in inducing tumour angiogenesis and how it contributes to cancer progression.     
  • Molecular mechanisms by which altered miRNA expression promote tumorigenesis    

Peer Reviewed Journals

  Year Publication
(2024) 'The response of muscle and inflammation-related miRNAs to breast cancer and its treatment'
Yanping J, Annuk H, Miller N, Zhang S, Gupta S,Gupta A (2024) 'The response of muscle and inflammation-related miRNAs to breast cancer and its treatment'. Breast Cancer Res Treat, [DOI] [Details]
(2024) 'Taste perception changes in Multiple Myeloma and Head & Neck cancer patients: A qualitative study'
Ghias K, Dowling M, Krawczyk J, Barrett E, Gupta A (2024) 'Taste perception changes in Multiple Myeloma and Head & Neck cancer patients: A qualitative study'. Clinical Nutrition, [DOI] [Details]
(2024) 'Exercise interventions for mitigating the persistent side effects of long COVID infection'
Gupta S, Sandhu S, Liu K, Gupta A (2024) 'Exercise interventions for mitigating the persistent side effects of long COVID infection'. Journal Of Sports Science, [Details]
(2024) 'The Effect of Exercise on Reducing Lymphedema Severity in Breast Cancer Survivors'
Lian, Y. Sandhu, S. Asefa, Y. Gupta, A. (2024) 'The Effect of Exercise on Reducing Lymphedema Severity in Breast Cancer Survivors'. Cancers (Basel)Cancers (Basel), [DOI] [Details]
(2024) 'Cancer survivorship: understanding the patients¿ journey and perspectives on post-treatment needs'
Hussey C, Hanbridge M, Dowling M, Gupta A (2024) 'Cancer survivorship: understanding the patients¿ journey and perspectives on post-treatment needs'. BMC Cancer, [DOI] [Details]
(2023) 'The miR-17-92 cluster: Yin and Yang in human cancers'
Zhao, W. Gupta, A. Krawczyk, J. Gupta, S. (2023) 'The miR-17-92 cluster: Yin and Yang in human cancers'. Cancer Treatment And Research Communications, [DOI] [Details]
(2023) 'RRM2 and CDC6 are novel effectors of XBP1-mediated endocrine resistance and predictive markers of tamoxifen sensitivity'
Barua, D. Sultana, A. Islam, M. N. Cox, F. Gupta, A. Gupta, S. (2023) 'RRM2 and CDC6 are novel effectors of XBP1-mediated endocrine resistance and predictive markers of tamoxifen sensitivity'. BMC Cancer, [DOI] [Details]
(2023) 'UPR-Induced miR-616 Inhibits Human Breast Cancer Cell Growth and Migration by Targeting c-MYC'
Arabkari, V. Sultana, A. Barua, D. Webber, M. Smith, T. Gupta, A. Gupta, S. (2023) 'UPR-Induced miR-616 Inhibits Human Breast Cancer Cell Growth and Migration by Targeting c-MYC'. International Journal Of Molecular Sciences, [DOI] [Details]
(2023) 'The impact of treatment-induced dysgeusia on the nutritional status of cancer patients'
Ghias K, Yanping J, Gupta A (2023) 'The impact of treatment-induced dysgeusia on the nutritional status of cancer patients'. Clinical Nutrition, [DOI] [Details]
(2022) 'Serum protein and electrolyte imbalances are associated with chemotherapy induced neutropenia'
Abbasi, B. Hayat, A. Lyons, M. Gupta, A. Gupta, S. (2022) 'Serum protein and electrolyte imbalances are associated with chemotherapy induced neutropenia'. Heliyon, [DOI] [Details]
(2022) 'MicroRNAs as biomarkers for monitoring cardiovascular changes in Type II Diabetes Mellitus (T2DM) and exercise'
Saini, V. M. Liu, K. R. Surve, A. S. Gupta, S. Gupta, A. (2022) 'MicroRNAs as biomarkers for monitoring cardiovascular changes in Type II Diabetes Mellitus (T2DM) and exercise'. Journal Of Diabetes Research, [DOI] [Details]
(2021) 'Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis'
Read, D. E. Gupta, A. Cawley, K. Fontana, L. Agostinis, P. Samali, A. Gupta, S. (2021) 'Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis'. Life (Basel, Switzerland), [DOI] [Details]
(2021) 'MicroRNAs as Potential Biomarkers for Exercise-Based Cancer Rehabilitation in Cancer Survivors'
Jiang, Y. Ghias, K. Gupta, S. Gupta, A. (2021) 'MicroRNAs as Potential Biomarkers for Exercise-Based Cancer Rehabilitation in Cancer Survivors'. Life (Basel, Switzerland), [DOI] [Details]
(2019) 'Management of Chemotherapy Induced Neutropenia ¿ an Unmet Clinical Need'
Gupta A, Abassi B, Gupta S (2019) 'Management of Chemotherapy Induced Neutropenia ¿ an Unmet Clinical Need'. BioMed Research International, [DOI] [Details]
(2018) 'Investigation of Anemia and the Dielectric Properties of Human Blood at Microwave Frequencies'
Santorelli A; Abbasi B; Lyons M; Hayat A; Gupta S, O'Halloran M, Gupta A (2018) 'Investigation of Anemia and the Dielectric Properties of Human Blood at Microwave Frequencies'. IEEE Access, [DOI] [Details]
(2023) 'miRNA-378 Is Downregulated by XBP1 and Inhibits Growth and Migration of Luminal Breast Cancer Cells'
Arabkari, V. Barua, D. Hossain, M. M. Webber, M. Smith, T. Gupta, A. Gupta, S. (2023) 'miRNA-378 Is Downregulated by XBP1 and Inhibits Growth and Migration of Luminal Breast Cancer Cells'. International Journal Of Molecular Sciences, [DOI] [Details]
(2022) 'Exercise interventions to combat cancer-related fatigue in cancer patients undergoing treatment: a review'
Hussey C, Gupta A (2022) 'Exercise interventions to combat cancer-related fatigue in cancer patients undergoing treatment: a review'. Cancer Investigation, [DOI] [Details]
(2022) 'Exercise interventions to combat cancer-related fatigue in cancer patients undergoing treatment: a review'
Hussey C, Gupta A (2022) 'Exercise interventions to combat cancer-related fatigue in cancer patients undergoing treatment: a review'. Cancer Investigation, 40 (9):822-838 [DOI] [Details]
(2020) 'Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges'
Barua D;Gupta A;Gupta S; (2020) 'Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges'. Cancer Letters, 486 [DOI] [Details]
(2020) 'Differential expression, function and prognostic value of miR-17-92 cluster in ER-positive and triple-negative breast cancer'
Hossain MM;Sultana A;Barua D;Islam MN;Gupta A;Gupta S; (2020) 'Differential expression, function and prognostic value of miR-17-92 cluster in ER-positive and triple-negative breast cancer'. Cancer Treatment And Research Communications, 25 [DOI] [Details]
(2020) 'XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation'
Barua D;Abbasi B;Gupta A;Gupta S; (2020) 'XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation'. Heliyon, 6 (10) [DOI] [Details]
(2020) 'XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation'
Barua, D,Abbasi, B,Gupta, A,Gupta, S (2020) 'XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation'. Heliyon, 6 [DOI] [Details]
(2018) 'Investigation of Anemia and Pie Dielectric Properties of Human Blood at Microwave Frequencies'
Santorelli, A;Abbasi, B;Lyons, M;Hayat, A;Gupta, S;O'Halloran, M;Gupta, A (2018) 'Investigation of Anemia and Pie Dielectric Properties of Human Blood at Microwave Frequencies'. IEEE Access, 6 :56885-56892 [DOI] [Details]
(2018) 'Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death'
Hossain MM;Barua D;Arabkari V;Islam N;Gupta A;Gupta S; (2018) 'Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death'. Oncotarget, 9 (14) [DOI] [Details]
(2018) 'Hyperactivation of nuclear receptor coactivators induces PERK- dependent cell death'
Muhammad Mosaraf Hossain, David Barua, Vahid Arabkari, Md Nahidul Islam, Ananya Gupta and Sanjeev Gupta (2018) 'Hyperactivation of nuclear receptor coactivators induces PERK- dependent cell death'. Oncotarget, [Details]
(2017) 'Glycosylation-Related Gene Expression in the Mucus-Secreting Gastrointestinal Cell Line HT29-MTX-E12 in Response to Infection by Helicobacter pylori'
Michael T Cairns; Ananya Gupta; Julie A Naughton; Marian Kane; Marguerite Clyne; Lokesh Joshi (2017) 'Glycosylation-Related Gene Expression in the Mucus-Secreting Gastrointestinal Cell Line HT29-MTX-E12 in Response to Infection by Helicobacter pylori'. Plos One, [Details]
(2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2 alpha-ATF4 signalling in breast cancer'
Gupta, A,Hossain, MM,Miller, N,Kerin, M,Callagy, G,Gupta, S (2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2 alpha-ATF4 signalling in breast cancer'. Oncogene, 35 :5860-5871 [DOI] [Details]
(2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer'
Gupta A, Hossain MM, Miller N, Kerin M, Callagy G, Gupta S. (2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer'. Oncogene, [Details]
(2016) 'Reduced CREB3L2 expression is associated with resistance to sorafenib and poor prognosis in ER-positive breast cancer'
Sean Mullarkey, Vahid Arabkari, Muhammad Mosaraf Hossain,Sanjeev Gupta, Ananya Gupta (2016) 'Reduced CREB3L2 expression is associated with resistance to sorafenib and poor prognosis in ER-positive breast cancer'. [DOI] [Details]
(2016) '1. IRE1-XBP1 regulates the expression of NCOA3 in breast cancer'
Ananya Gupta, Mosaraf Hossain, Mark Webber, Nicola Miller, Grace Callagy and Sanjeev Gupta (2016) '1. IRE1-XBP1 regulates the expression of NCOA3 in breast cancer'. Oncogene, [Details]
(2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2 alpha-ATF4 signalling in breast cancer'
Gupta, A;Hossain, MM;Miller, N;Kerin, M;Callagy, G;Gupta, S (2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2 alpha-ATF4 signalling in breast cancer'. Oncogene, 35 :5860-5871 [DOI] [Details]
(2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2¿-ATF4 signalling in breast cancer'
Gupta A;Hossain MM;Miller N;Kerin M;Callagy G;Gupta S; (2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2¿-ATF4 signalling in breast cancer'. Oncogene, [DOI] [Details]
(2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways'
Gupta, A;Read, DE;Gupta, S (2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways'. Methods in Molecular Biology, 1292 :19-38 [DOI] [Details]
(2015) 'PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'
Gupta, A;Hossain, MM;Read, DE;Hetz, C;Samali, A;Gupta, S (2015) 'PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'. Scientific Reports, 5 [DOI] [Details]
(2015) 'PERK regulated miR-424-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'
Ananya Gupta, Mosaraf Hossain, Danielle Read, Mark Webber and Sanjeev Gupta. (2015) 'PERK regulated miR-424-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'. Scientific Reports, [DOI] [Details]
(2015) 'PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'
Gupta, A,Hossain, MM,Read, DE,Hetz, C,Samali, A,Gupta, S (2015) 'PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'. Scientific Reports, 5 [DOI] [Details]
(2014) 'miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts'
Read, DE,Gupta, A,Ladilov, Y,Samali, A,Gupta, S (2014) 'miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts'. Cell And Bioscience, 4 [DOI] [ARAN Link] [Details]
(2014) 'miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts'
Read DE, Gupta A;Ladilov Y;Samali A;Gupta S (2014) 'miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts'. Cell And Bioscience, 4 (1) [DOI] [Details]
(2012) 'Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis'
Gupta, S,Read, DE,Deepti, A,Cawley, K,Gupta, A,Oommen, D,Verfaillie, T,Matus, S,Smith, MA,Mott, JL,Agostinis, P,Hetz, C,Samali, A (2012) 'Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis'. Cell Death & Disease, 3 [DOI] [Details]
(2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'
Gupta, A,Caffrey, E,Callagy, G,Gupta, S (2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'. Biochemical Society Transactions, 40 :752-758 [DOI] [Details]
(2012) 'Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis'
Gupta S, Read DE, Deepti A, Cawley K, Gupta A, Oommen D, Verfaillie T, Matus S, Smith MA, Mott JL, Agostinis P, Hetz C, Samali A (2012) 'Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis'. Cell Death & Disease, 3 [DOI] [Details]
(2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'
Gupta, A;Caffrey, E;Callagy, G;Gupta, S (2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'. Biochemical Society Transactions, 40 :752-758 [DOI] [Details]
(2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'
Gupta A, Caffrey E, Callagy G, Gupta S. (2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'. [DOI] [Details]
(2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE'
Cawley, K;Deegan, S;Samali, A;Gupta, S (2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE'. Methods In Enzymology: Unfolded Protein Response And Cellular Stress, Vol 490, Pt B, 490 :31-51 [DOI] [Details]
(2011) 'Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract'
Moran, AP;Gupta, A;Joshi, L (2011) 'Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract'. Gut, 60 :1412-1425 [DOI] [Details]
(2011) 'Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract'
Moran, AP,Gupta, A,Joshi, L (2011) 'Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract'. Gut, 60 :1412-1425 [DOI] [Details]
(2011) 'Assays for detecting the unfolded protein response'
Cawley K, Deegan S, Samali A, Gupta S (2011) 'Assays for detecting the unfolded protein response'. Methods Enzymol, 490 :31-51 [DOI] [Details]
(2011) 'Assays for detecting the unfolded protein response'
Cawley K, Deegan S, Samali A, Gupta S. (2011) 'Assays for detecting the unfolded protein response'. Methods Enzymol, 490 :31-51 [Details]

Books

  Year Publication
(2023) Muse -Music And Poetry To Empower Teenagers Resilience at School.
Gupta A (2023) Muse -Music And Poetry To Empower Teenagers Resilience at School. Ireland: University of Galway. [DOI] [Details]
(2022) YOUNG PEOPLE PRACTISING HEALTH EDUCATIONAL TOOLS FOR WELLBEING THROUGH SPORT AND NUTRITION.
Gupta A (2022) YOUNG PEOPLE PRACTISING HEALTH EDUCATIONAL TOOLS FOR WELLBEING THROUGH SPORT AND NUTRITION. Italy: IUL Press Firenze. [DOI] [Details]

Book Chapters

  Year Publication
(2023) 'Chapter 1: The scientific and pedagogical basis of resilience'
Giuseppe Carrus, Chiara Massullo, Chiara Massullo, Marcin Fabjanky, Ananya Gupta (2023) 'Chapter 1: The scientific and pedagogical basis of resilience' In: MuSE ¿ Music And Poetry To Empower Teenagers Resilience at School. Ireland: University of Galway. [DOI] [Details]
(2022) 'Physical Activity Guidelines and Recommendations in EU'
Hussey C, Gupta A (2022) 'Physical Activity Guidelines and Recommendations in EU' In: YOUNG PEOPLE PRACTISING HEALTH EDUCATIONAL TOOLS FOR WELLBEING THROUGH SPORT AND NUTRITION. Italy: IUL Press Firenze. [DOI] [Details]
(2022) 'Importance of physical activity and its impact on growth, development and health'
Hussey C, Gupta A (2022) 'Importance of physical activity and its impact on growth, development and health' In: YOUNG PEOPLE PRACTISING HEALTH EDUCATIONAL TOOLS FOR WELLBEING THROUGH SPORT AND NUTRITION. Italy: IUL Press Firenze. [DOI] [Details]
(2022) 'Health Benefits of Physical Activity'
Hussey C, Gupta A (2022) 'Health Benefits of Physical Activity' In: YOUNG PEOPLE PRACTISING HEALTH EDUCATIONAL TOOLS FOR WELLBEING THROUGH SPORT AND NUTRITION. Italy: IUL Press Firenze. [DOI] [Details]
(2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways'
Gupta, A,Read, DE,Gupta, S,Oslowski, CM (2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways' In: Method and Protocols. :19-38 UK: Elsevier Inc. [DOI] [Details]
(2015) 'Assays for induction of the unfolded protein response and selective activation of the three major pathways'
Gupta A, Read DE, Gupta S (2015) 'Assays for induction of the unfolded protein response and selective activation of the three major pathways' In: Stress Responses - Methods and Protocols. Europe: Springer Link. [Details]
(2012) 'Regulation of ER Stress Responses by microRNAs'
Danielle E Read, Ananya Gupta, Karen Cawley, Sanjeev Gupta (2012) 'Regulation of ER Stress Responses by microRNAs' In: Endoplasmic Reticulum Stress in Health and Disease. UK: Springerlink. [DOI] [Details]
(2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE'
Cawley, K,Deegan, S,Samali, A,Gupta, S (2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE' In: Methods in enzymology. :31-51 UK: Elsevier Inc. [DOI] [Details]

Conference Publications

  Year Publication
(2020) American Association for Cancer Research. 2020
D Barua, A Sultana, MN Islam, A Gupta, S Gupta (2020) XBP1 regulates the expression of cell cycle associated genes in ERα positive breast cancer cells. Cancer Research 80 (16 Supplement), 5843-5843 American Association for Cancer Research. 2020 [Details]
(2017) 15th CELT Symposium on Higher Education - Learning Communities, Collaboration, and Collegiality
Dempsey, M., Burns, D., Flynn, S., Gupta, A., Hogan, M., MacLochlainn, M., O’Connell, J., Ó Sealbhaigh, F. (2017) MISFITS: Lego, Wool, Art, Equations agus Seanfhocail: Professional Development Pilot ¿a living teaching portfolio initiative 15th CELT Symposium on Higher Education - Learning Communities, Collaboration, and Collegiality [ARAN Link] [Details]
(2017) San Antonio Breast Cancer Symposium; 2017 Dec 5-9
MM Hossain, V Arabkari, D Barua, A Gupta, MN Islam and S Gupta (2017) miR-17-92 cluster, an oncogenic microRNA cluster acts as a context dependent tumour suppressor in breast cancer. Cancer Res 2018;78(4 Suppl):Abstract nr P5-07-14 San Antonio Breast Cancer Symposium; 2017 Dec 5-9 [Details]
(2013) Perk-dependent repression of miR-106b-25 cluster is required for ER stress induced apoptosis
Read, DE,Agostinis, P,Hetz, C,Mott, JL,Samali, A,Gupta, S (2013) Perk-dependent repression of miR-106b-25 cluster is required for ER stress induced apoptosis , pp.117-120 [Details]

Edited Books

  Year Publication
(2023) Muse -Music And Poetry To Empower Teenagers Resilience at School.
Gupta A (Ed.). (2023) Muse -Music And Poetry To Empower Teenagers Resilience at School Muse -Music And Poetry To Empower Teenagers Resilience at School. Ireland: University of Galway. [DOI] [Details]

Other Journals

  Year Publication
(2015) 'Loss of Dicer1 in mouse embryonic fibroblasts impairs ER stress-induced apoptosis'
A Gupta, D Read, D Oommen, A Samali, S Gupta (2015) 'Loss of Dicer1 in mouse embryonic fibroblasts impairs ER stress-induced apoptosis' BioRxiv, . [Details]
(2016) 'Reduced CREB3L2 expression is associated with resistance to sorafenib and poor prognosis in ER-positive breast cancer'
S Mullarkey, V Arabkari, MM Hossain, S Gupta, A Gupta (2016) 'Reduced CREB3L2 expression is associated with resistance to sorafenib and poor prognosis in ER-positive breast cancer' BioRxiv, . [Details]
'Loss of Dicer1 in mouse embryonic fibroblasts impairs ER stress-induced apoptosis'
Ananya Gupta, Danielle Read, Deepu Oommen, Afshin Samali, SANJEEV GUPTA 'Loss of Dicer1 in mouse embryonic fibroblasts impairs ER stress-induced apoptosis' Biorxiv, . [DOI] [Details]

Conference Contributions

  Year Publication
(2015) IACR Annual Meeting,
A Gupta, MM Hossain, G Callagy, S Gupta (2015) XBP1 regulates the expression of NCOA3/AIB1 during unfolded protein response in breast cancer cells. [Poster Presentation], IACR Annual Meeting, Limerick, Ireland , 26-FEB-15 - 27-FEB-15. [Details]
(2014) IACR Annual Meeting,
A Gupta, G Callagy, S Gupta. (2014) Regulation of NCOA3/AIB1 expression by the unfolded protein response. [Poster Presentation], IACR Annual Meeting, Galway, Ireland , 27-MAR-14 - 28-MAR-14. [Details]
(2013) Edinburgh Pathology 2013, Joint Meeting with the BDIAP,
H Ingoldsby, E Caffrey, M Webber, D Wall, A Gupta, J Newell, S Gupta, G Callagy (2013) Characterisation of miR-4726 and miR-4728 in breast cancer. [Poster Presentation (Refereed)], Edinburgh Pathology 2013, Joint Meeting with the BDIAP, Edinburgh, UK , 18-JUN-13 - 21-JUN-13. [Details]

Abstract

  Year Publication
(2010) Co-ordinated regulation of gene expression by H-pylori in response to low pH and iron limiting growth conditions.
Moran, AP,Gupta, A,Ustinov, S,Mashayekhi, K (2010) Co-ordinated regulation of gene expression by H-pylori in response to low pH and iron limiting growth conditions. Abstract [Details]

Editorial

  Year Publication
(2018) miR-17-92 cluster, an oncogenic microRNA cluster acts as a context dependent tumour suppressor in breast cancer.
Hossain, MM,Arabkari, V,Barua, D,Gupta, A,Islam, MN,Gupta, S (2018) miR-17-92 cluster, an oncogenic microRNA cluster acts as a context dependent tumour suppressor in breast cancer. Editorial [Details]

Reviews

  Year Publication
(2020) Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges.
Barua, D;Gupta, A;Gupta, S (2020) Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges. CLARE: ELSEVIER IRELAND LTD Reviews [DOI] [Details]

Video recording / TV

  Year Publication
(2017) LSP for PD in Action.
Dempsey, M., Burns, D., Flynn, S., Gupta, A., Hogan, M., MacLochlainn, M., O’Connell, J., Ó Sealbhaigh, F. (2017) LSP for PD in Action. Mansion House, Dublin: National Forum for the Enhancement of Teaching and Learning in Higher Education Video recording / TV [Details]
(2017) Professional Development Pilot: National Framework of Teaching and Learning in Higher Education.
Dempsey, M., Burns, D., Flynn, S., Gupta, A., Hogan, M., MacLochlainn, M., O’Connell, J., Ó Sealbhaigh, F. (2017) Professional Development Pilot: National Framework of Teaching and Learning in Higher Education. Video recording / TV [Details]

Honours and Awards

  Year Title Awarding Body
2007 Marie Curie Transfer of Knowledge Fellow Marie Skłodowska Curie Foundation
1999 Senior Research Fellowship CSIR-UGC India
1997 Junior Research Fellowship CSIR-UGC India

Professional Associations

  Association Function From / To
Physiology Society full Member /
Society of Cell Biologists, India Member /
European Association of Cancer Research Member /
American Association of Cancer Research Member /
Society for General Microbiology, Ireland Member /
Academy of Medical Laboratory Science Full Member /
Indian Biophysical Society, India Member /
Irish Association for Cancer research, Ireland Member /

Committees

  Committee Function From / To
Graduate Research Council Student Advisor /

Employment

  Employer Position From / To
NUI Galway Lecturer (above the bar) 07-JAN-16 /
NUI Galway Postdoctoral researcher 10-FEB-12 / 30-SEP-15
NUI Galway Postdoctoral researcher 07-JUL-09 / 31-AUG-11
NUI Galway Marie Curie Transfer of Knowledge Research Fellow 25-SEP-07 / 30-SEP-08
University of Pennsylvania, Philadelphia, USA Research Associate 04-JAN-04 /
Orchid Pharmaceuticals Ltd. India Senior scientist and Head of Cancer Drug Discovery 01-JUN-06 / 01-AUG-07

Education

  Year Institution Qualification Subject
1995 Presidency College Calcutta India, Calcutta University BSc (Hons) Physiology
2016 CELT, NUI Galway Postgraduate Certificate in Higher Education Teaching Teaching and Learning in Higher Education
1997 Calcutta university Msc Biophysics and Molecular biology
2005 Centre for Cellular and Molecular Biology, Jawaharlal Nehru University, India PhD Lifesciences - Immunology and host pathogen interactions

Languages

  Language
English

Community Engagement

  Title Type From / To
Outreach Teen Tech /
Outreach Cell Exploreres /

Reviews

  Journal Role
Journal Of Cellular And Molecular Medicine Reviewer
Scientific Reports Reviewer
Plos One Reviewer
Journal Of Biological Chemistry Reviewer
Apoptosis Reviewer
Biochem Biophy Res Commun Reviewer
Am J Physiol Cell Physiol Reviewer

Teaching Interests

My Teaching philosophy I believe my role, as teacher, is to bring to students the same interest that I feel for my subject. If this is accomplished then each individual student can achieve to the best of their capability. To achieve this, my first goal is to engage students by presenting the appropriate material for each topic in an interesting and enjoyable lesson, my second is to ensure that students understand the topic being taught, and third is to encourage students to appreciate the inherent connections amongst various topics being taught and lastly to continuously assess level of student understanding. I use different methods of teaching and assessment depending on the resources available, the time available and the number and background of students being taught. To make each particular lesson interesting and topical, I use common biological examples, including recent examples from my own research experiences or colleagues’ work, published literature or from well-known processes or diseases. I provide extra reading and audio-visual material to support what is taught in class. I also try to finish up a topic with a tutorial or problem solving session, where I can gauge the level of comprehension and interest. In order to develop and improve my teaching, I review all the material that I teach regularly. As a teacher I have a responsibility towards students to convey the appropriate knowledge, in an organized manner, in a stimulating environment; to clearly explain what is expected and accurately assess achievements. I use learning outcomes to clearly state what it is that a student will be expected to demonstrate on completion of a particular topic, this not only reassures the student, it helps them learn more effectively. When aligned with teaching/learning activities and assessment methods this provides a transparent, logical framework for defining what needs to be learned, how it will be taught and how it will be assessed. In addition to helping students to learn and appreciate the subject, I feel that we have an obligation to help them with respect to their futures. Many students are not aware of the career options available to them. I like to inform the students about the subject choices and career paths that are open to them, and how best to embark on such paths. 

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2016 Anhar Abdullah Msc Y
2013 Louise Conlon Msc
2014 Siobhan Kenny Msc
2015 Alan O’Dwyer Msc

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
Biomedical Science 3rd Yer Advanced Cardiovascular Physiology SI326
MSc in Exercise Physiology Exercise Physiology Laboratory module ET1505
One year Masters course MSc in Exercise Physiology EPT1 Course Director
MSc in Exercise Physiology Integrated Responses to Exercise ET1501
MSc in Exercise Physiology Principles of Exercise Testing and Prescription ET1503
MSc in Exercise Physiology Exercise Prescription in Chronic Disease ET1504
MSc in Exercise Physiology Introduction to Exercise Physiology ET1500
Higher Diploma in Applied Science Applied Microbiology and Immunology AM1
Nursing Year 1 Physiology NU115
Biomedical Science BSc 4th Year Case based Physiology SI4101
MD Year 1 Principles of Physiology MD137
Biomedical Science BSc 2nd Year Respiratory Physiology SI212
Biomedical Science BSc 4th Year Pathophysiology SI432
MD Year 1 Cardiovascular Physiology MD121 module coordinator
PG Diploma in Microbiology Applied Microbiology and Immunology PGM1
Biomedical Science BSc 2nd Year Cardiovascular Physiology SI208
Master of Cancer Biology Molecular and cellular biology of cancer GYT91
BSc Microbiology Year 3 Immunology MI317
Biomedical Science BSc 4th Year Research Project SI435
Nursing Year 3 Physiology NuU306
BSc Microbiology Year 3 Immunology MI330
Higher Diploma in Applied Science (Microbiology) Analytical Microbiology and Quality Management Systems MI504
Master of Science Biotechnology MT1