Staff List

PROF GARRY DUFFY

BSc (Hons)

Biography

Peer Reviewed Journals

	Year	Publication
	(2018)	'Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart' Mencía Castaño, Curtin CM, Duffy GP, O'Brien FJ (2018) 'Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart'. Tissue Engineering Part A, [DOI] [Details]
	(2018)	'A collagen cardiac patch incorporating alginate microparticles permits the controlled release of hepatocyte growth factor and insulin-like growth factor-1 to enhance cardiac stem cell migration and proliferation' O'Neill, HS;O'Sullivan, J;Porteous, N;Ruiz-Hernandez, E;Kelly, HM;O'Brien, FJ;Duffy, GP (2018) 'A collagen cardiac patch incorporating alginate microparticles permits the controlled release of hepatocyte growth factor and insulin-like growth factor-1 to enhance cardiac stem cell migration and proliferation'. Journal Of Tissue Engineering And Regenerative Medicine, 12 :384-394 [DOI] [Details]
	(2018)	'Sustained release of targeted cardiac therapy with a replenishable implanted epicardial reservoir' Whyte, W;Roche, ET;Varela, CE;Mendez, K;Islam, S;O'Neill, H;Weafer, F;Shirazi, RN;Weaver, JC;Vasilyev, NV;McHugh, PE;Murphy, B;Duffy, GP;Walsh, CJ;Mooney, DJ (2018) 'Sustained release of targeted cardiac therapy with a replenishable implanted epicardial reservoir'. Nature Biomedical Engineering, 2 :416-428 [DOI] [Details]
	(2018)	'Optimization of cell growth on palmitoyl-hyaluronan knitted scaffolds developed for tissue engineering applications' Sogorkova, J;Zapotocky, V;Cepa, M;Stepankova, V;Vagnerova, H;Batova, J;Pospisilova, M;Betak, J;Nesporova, K;Hermannova, M;Daro, D;Duffy, G;Velebny, V (2018) 'Optimization of cell growth on palmitoyl-hyaluronan knitted scaffolds developed for tissue engineering applications'. Journal Of Biomedical Materials Research Part A, 106 :1488-1499 [DOI] [Details]
	(2017)	'Direct UV-Triggered Thiol-ene Cross-Linking of Electrospun Polyester Fibers from Unsaturated Poly(macrolactone)s and Their Drug Loading by Solvent Swelling' de Oliveira, FCS;Olvera, D;Sawkins, MJ;Cryan, SA;Kimmins, SD;da Silva, TE;Kelly, DJ;Duffy, GP;Kearney, C;Heise, A (2017) 'Direct UV-Triggered Thiol-ene Cross-Linking of Electrospun Polyester Fibers from Unsaturated Poly(macrolactone)s and Their Drug Loading by Solvent Swelling'. Biomacromolecules, 18 :4292-4298 [DOI] [Details]
	(2017)	'Olfactory Derived Stem Cells Delivered in a Biphasic Conduit Promote Peripheral Nerve Repair In Vivo' Roche, P;Alekseeva, T;Widaa, A;Ryan, A;Matsiko, A;Walsh, M;Duffy, GP;O'Brien, FJ (2017) 'Olfactory Derived Stem Cells Delivered in a Biphasic Conduit Promote Peripheral Nerve Repair In Vivo'. Stem Cells Translational Medicine, 6 :1894-1904 [DOI] [Details]
	(2017)	'Advances in polymeric islet cell encapsulation technologies to limit the foreign body response and provide immunoisolation' Ryan, AJ;O'Neill, HS;Duffy, GP;O'Brien, FJ (2017) 'Advances in polymeric islet cell encapsulation technologies to limit the foreign body response and provide immunoisolation'. Current Opinion In Pharmacology, 36 :66-71 [DOI] [Details]
	(2017)	'A stimuli responsive liposome loaded hydrogel provides flexible on-demand release of therapeutic agents' O'Neill, HS;Herron, CC;Hastings, CL;Deckers, R;Noriega, AL;Kelly, HM;Hennink, WE;McDonnell, CO;O'Brien, FJ;Ruiz-Hernandez, E;Duffy, GP (2017) 'A stimuli responsive liposome loaded hydrogel provides flexible on-demand release of therapeutic agents'. Acta Biomaterialia, 48 :110-119 [DOI] [Details]
	(2017)	'An in vitro investigation to assess procedure parameters for injecting therapeutic hydrogels into the myocardium' Curley, CJ;Dolan, EB;Cavanagh, B;O'Sullivan, J;Duffy, GP;Murphy, BP (2017) 'An in vitro investigation to assess procedure parameters for injecting therapeutic hydrogels into the myocardium'. Journal Of Biomedical Materials Research Part B-Applied Biomaterials, 105 :2618-2629 [DOI] [Details]
	(2017)	'Fabrication of biodegradable textile scaffold based on hydrophobized hyaluronic acid' Zapotocky, V;Pospisilova, M;Janouchova, K;Svadlak, D;Batova, J;Sogorkova, J;Cepa, M;Betak, J;Stepankova, V;Sulakova, R;Kulhanek, J;Pitucha, T;Vranova, J;Duffy, G;Velebny, V (2017) 'Fabrication of biodegradable textile scaffold based on hydrophobized hyaluronic acid'. International Journal Of Biological Macromolecules, 95 :903-909 [DOI] [Details]
	(2016)	'Next generation bone tissue engineering: non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis' Castano, IM;Curtin, CM;Duffy, GP;O'Brien, FJ (2016) 'Next generation bone tissue engineering: non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis'. Scientific Reports, 6 [DOI] [Details]
	(2016)	'Effect of collagen-glycosaminoglycan scaffold pore size on matrix mineralization and cellular behavior in different cell types' Murphy, CM;Duffy, GP;Schindeler, A;O'brien, FJ (2016) 'Effect of collagen-glycosaminoglycan scaffold pore size on matrix mineralization and cellular behavior in different cell types'. Journal Of Biomedical Materials Research Part A, 104 :291-304 [DOI] [Details]
	(2016)	'Delivering Nucleic-Acid Based Nanomedicines on Biomaterial Scaffolds for Orthopedic Tissue Repair: Challenges, Progress and Future Perspectives' Raftery, RM;Walsh, DP;Castano, IM;Heise, A;Duffy, GP;Cryan, SA;O'Brien, FJ (2016) 'Delivering Nucleic-Acid Based Nanomedicines on Biomaterial Scaffolds for Orthopedic Tissue Repair: Challenges, Progress and Future Perspectives'. Advanced Materials (Deerfield Beach, Fla.), 28 :5447-5469 [DOI] [Details]
	(2015)	'Investigating the effect of hypoxic culture on the endothelial differentiation of human amniotic fluid-derived stem cells' Lloyd-Griffith, C;Duffy, GP;O'Brien, FJ (2015) 'Investigating the effect of hypoxic culture on the endothelial differentiation of human amniotic fluid-derived stem cells'. Journal Of Anatomy, 227 :767-780 [DOI] [Details]
	(2015)	'A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and antagomiRs to human mesenchymal stem cells' Castano, IM;Curtin, CM;Shaw, G;Murphy, JM;Duffy, GP;O'Brien, FJ (2015) 'A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and antagomiRs to human mesenchymal stem cells'. Journal Of Controlled Release, 200 :42-51 [DOI] [Details]
	(2015)	'Combinatorial Gene Therapy Accelerates Bone Regeneration: Non-Viral Dual Delivery of VEGF and BMP2 in a Collagen-Nanohydroxyapatite Scaffold' Curtin, CM;Tierney, EG;McSorley, K;Cryan, SA;Duffy, GP;O'Brien, FJ (2015) 'Combinatorial Gene Therapy Accelerates Bone Regeneration: Non-Viral Dual Delivery of VEGF and BMP2 in a Collagen-Nanohydroxyapatite Scaffold'. Advanced Healthcare Materials, 4 :223-227 [DOI] [Details]
	(2015)	'THE EFFECT OF BISPHOSPHONATE TREATMENT ON THE BIOCHEMICAL AND CELLULAR EVENTS DURING BONE REMODELLING IN RESPONSE TO MICROINJURY STIMULATION' Mulcahy, LE;Curtin, CM;McCoy, RJ;O'Brien, FJ;Taylor, D;Lee, TC;Duffy, GP (2015) 'THE EFFECT OF BISPHOSPHONATE TREATMENT ON THE BIOCHEMICAL AND CELLULAR EVENTS DURING BONE REMODELLING IN RESPONSE TO MICROINJURY STIMULATION'. European Cells & Materials, 30 :271-281 [Details]
	(2015)	'The pre-vascularisation of a collagen-chondroitin sulphate scaffold using human amniotic fluid-derived stem cells to enhance and stabilise endothelial cell-mediated vessel formation' Lloyd-Griffith, C;McFadden, TM;Duffy, GP;Unger, RE;Kirkpatrick, CJ;O'Brien, FJ (2015) 'The pre-vascularisation of a collagen-chondroitin sulphate scaffold using human amniotic fluid-derived stem cells to enhance and stabilise endothelial cell-mediated vessel formation'. Acta Biomaterialia, 26 :263-273 [DOI] [Details]
	(2015)	'Spatiotemporal delivery of small molecule therapeutics using a thermosensitive liposome loaded hydrogel' O'Neill H, Herron C, Hastings C, Lopez-Noriega A, Kelly HM, O'Brien FJ, Ruiz-Hernandez E, Duffy GP. (2015) 'Spatiotemporal delivery of small molecule therapeutics using a thermosensitive liposome loaded hydrogel'. Journal Of Controlled Release, 213 :e28-e29 [DOI] [Details]
	(2014)	'The application of a thermoresponsive chitosan/beta-GP gel to enhance cell repopulation of decellularized vascular scaffolds' Sheridan, WS;Grant, OB;Duffy, GP;Murphy, BP (2014) 'The application of a thermoresponsive chitosan/beta-GP gel to enhance cell repopulation of decellularized vascular scaffolds'. Journal Of Biomedical Materials Research Part B-Applied Biomaterials, 102 :1700-1710 [DOI] [Details]
	(2014)	'An Experimental Investigation of the Effect of Mechanical and Biochemical Stimuli on Cell Migration Within a Decellularized Vascular Construct' Sheridan, WS;Ryan, AJ;Duffy, GP;O'Brien, FJ;Murphy, BP (2014) 'An Experimental Investigation of the Effect of Mechanical and Biochemical Stimuli on Cell Migration Within a Decellularized Vascular Construct'. Annals Of Biomedical Engineering, 42 :2029-2038 [DOI] [Details]
	(2014)	'Enhanced delivery of microRNA mimics to cardiomyocytes using ultrasound responsive microbubbles reverses hypertrophy in an in-vitro model' Gill, SL;O'Neill, H;McCoy, RJ;Logeswaran, S;O'Brien, F;Stanton, A;Kelly, H;Duffy, GP (2014) 'Enhanced delivery of microRNA mimics to cardiomyocytes using ultrasound responsive microbubbles reverses hypertrophy in an in-vitro model'. Technology And Health Care, 22 :37-51 [DOI] [Details]
	(2014)	'Comparison of biomaterial delivery vehicles for improving acute retention of stem cells in the infarcted heart' Roche, ET;Hastings, CL;Lewin, SA;Shvartsman, DE;Brudno, Y;Vasilyev, NV;O'Brien, FJ;Walsh, CJ;Duffy, GP;Mooney, DJ (2014) 'Comparison of biomaterial delivery vehicles for improving acute retention of stem cells in the infarcted heart'. Biomaterials, 35 :6850-6858 [DOI] [Details]
	(2014)	'Hyperthermia-Induced Drug Delivery from Thermosensitive Liposomes Encapsulated in an Injectable Hydrogel for Local Chemotherapy' Lopez-Noriega, A;Hastings, CL;Ozbakir, B;O'Donnell, KE;O'Brien, FJ;Storm, G;Hennink, WE;Duffy, GP;Ruiz-Hernandez, E (2014) 'Hyperthermia-Induced Drug Delivery from Thermosensitive Liposomes Encapsulated in an Injectable Hydrogel for Local Chemotherapy'. Advanced Healthcare Materials, 3 :854-859 [DOI] [Details]
	(2013)	'Supramolecular Hydrogels with Reverse Thermal Gelation Properties from (Oligo)tyrosine Containing Block Copolymers' Huang, J;Hastings, CL;Duffy, GP;Kelly, HM;Raeburn, J;Adams, DJ;Heise, A (2013) 'Supramolecular Hydrogels with Reverse Thermal Gelation Properties from (Oligo)tyrosine Containing Block Copolymers'. Biomacromolecules, 14 :200-206 [DOI] [Details]
	(2013)	'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix' Tierney, EG;McSorley, K;Hastings, CL;Cryan, SA;O'Brien, T;Murphy, MJ;Barry, FP;O'Brien, FJ;Duffy, GP (2013) 'High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix'. Journal Of Controlled Release, 165 :173-182 [DOI] [Details]
	(2013)	'Encapsulation of cardiac stem cells in superoxide dismutase-loaded alginate prevents doxorubicin-mediated toxicity' Liu, TCK;Ismail, S;Brennan, O;Hastings, C;Duffy, GP (2013) 'Encapsulation of cardiac stem cells in superoxide dismutase-loaded alginate prevents doxorubicin-mediated toxicity'. Journal Of Tissue Engineering And Regenerative Medicine, 7 :302-311 [DOI] [Details]
	(2013)	'Non-viral gene-activated matrices Next generation constructs for bone repair' Tierney, EG;Duffy, GP;Cryan, SA;Curtin, CM;O'Brien, FJ (2013) 'Non-viral gene-activated matrices Next generation constructs for bone repair'. Organogenesis, 9 :22-28 [DOI] [Details]
	(2013)	'Orchestrating Osteogenic Differentiation of Mesenchymal Stem Cells-Identification of Placental Growth Factor as a Mechanosensitive Gene with a Pro-Osteogenic Role' McCoy, RJ;Widaa, A;Watters, KM;Wuerstle, M;Stallings, RL;Duffy, GP;O'Brien, FJ (2013) 'Orchestrating Osteogenic Differentiation of Mesenchymal Stem Cells-Identification of Placental Growth Factor as a Mechanosensitive Gene with a Pro-Osteogenic Role'. Stem Cells (Dayton, Ohio), 31 :2420-2431 [DOI] [Details]
	(2013)	'Optimum Parameters for Freeze-Drying Decellularized Arterial Scaffolds' Sheridan, WS;Duffy, GP;Murphy, BP (2013) 'Optimum Parameters for Freeze-Drying Decellularized Arterial Scaffolds'. Tissue Engineering Part C-Methods, 19 :981-990 [DOI] [Details]
	(2013)	'The delayed addition of human mesenchymal stem cells to pre-formed endothelial cell networks results in functional vascularization of a collagen-glycosaminoglycan scaffold in vivo' McFadden, TM;Duffy, GP;Allen, AB;Stevens, HY;Schwarzmaier, SM;Plesnila, N;Murphy, JM;Barry, FP;Guldberg, RE;O'Brien, FJ (2013) 'The delayed addition of human mesenchymal stem cells to pre-formed endothelial cell networks results in functional vascularization of a collagen-glycosaminoglycan scaffold in vivo'. Acta Biomaterialia, 9 :9303-9316 [DOI] [Details]
	(2013)	'Mesenchymal stem cells to augment therapeutic angiogenesis in hind-limb ischemia models: how important is their source?' Duffy GP, Herron CC. (2013) 'Mesenchymal stem cells to augment therapeutic angiogenesis in hind-limb ischemia models: how important is their source?'. Stem Cell Research And Therapy, 4 :131-131 [DOI] [Details]
	(2012)	'Mechanical characterization of a customized decellularized scaffold for vascular tissue engineering' Sheridan, WS;Duffy, GP;Murphy, BP (2012) 'Mechanical characterization of a customized decellularized scaffold for vascular tissue engineering'. Journal Of The Mechanical Behavior Of Biomedical Materials, 8 :58-70 [DOI] [Details]
	(2012)	'The development of non-viral gene-activated matrices for bone regeneration using polyethyleneimine (PEI) and collagen-based scaffolds' Tierney, EG;Duffy, GP;Hibbitts, AJ;Cryan, SA;O'Brien, FJ (2012) 'The development of non-viral gene-activated matrices for bone regeneration using polyethyleneimine (PEI) and collagen-based scaffolds'. Journal Of Controlled Release, 158 :304-311 [DOI] [Details]
	(2012)	'Innovative Collagen Nano-Hydroxyapatite Scaffolds Offer a Highly Efficient Non-Viral Gene Delivery Platform for Stem Cell-Mediated Bone Formation' Curtin, CM;Cunniffe, GM;Lyons, FG;Bessho, K;Dickson, GR;Duffy, GP;O'Brien, FJ (2012) 'Innovative Collagen Nano-Hydroxyapatite Scaffolds Offer a Highly Efficient Non-Viral Gene Delivery Platform for Stem Cell-Mediated Bone Formation'. Advanced Materials (Deerfield Beach, Fla.), 24 [DOI] [Details]
	(2012)	'Development of a thermoresponsive chitosan gel combined with human mesenchymal stem cells and desferrioxamine as a multimodal pro-angiogenic therapeutic for the treatment of critical limb ischaemia' Hastings, CL;Kelly, HM;Murphy, MJ;Barry, FP;O'Brien, FJ;Duffy, GP (2012) 'Development of a thermoresponsive chitosan gel combined with human mesenchymal stem cells and desferrioxamine as a multimodal pro-angiogenic therapeutic for the treatment of critical limb ischaemia'. Journal Of Controlled Release, 161 :73-80 [DOI] [Details]
	(2011)	'RANKL and OPG activity is regulated by injury size in networks of osteocyte-like cells' Mulcahy, LE;Taylor, D;Lee, TC;Duffy, GP (2011) 'RANKL and OPG activity is regulated by injury size in networks of osteocyte-like cells'. Bone, 48 :182-188 [DOI] [Details]
	(2011)	'Temporal and Spatial Changes in Cartilage-Matrix-Specific Gene Expression in Mesenchymal Stem Cells in Response to Dynamic Compression' Haugh, MG;Meyer, EG;Thorpe, SD;Vinardell, T;Duffy, GP;Kelly, DJ (2011) 'Temporal and Spatial Changes in Cartilage-Matrix-Specific Gene Expression in Mesenchymal Stem Cells in Response to Dynamic Compression'. Tissue Engineering Part A, 17 :3085-3093 [DOI] [Details]
	(2011)	'TOWARDS IN VITRO VASCULARISATION OF COLLAGEN-GAG SCAFFOLDS' Duffy, GP;McFadden, TM;Byrne, EM;Gill, SL;Farrell, E;O'Brien, FJ (2011) 'TOWARDS IN VITRO VASCULARISATION OF COLLAGEN-GAG SCAFFOLDS'. European Cells & Materials, 21 :15-30 [Details]
	(2010)	'Mesenchymal Stem Cells Overexpressing Ephrin-B2 Rapidly Adopt an Early Endothelial Phenotype with Simultaneous Reduction of Osteogenic Potential' Duffy, GP;D'Arcy, S;Ahsan, T;Nerem, RM;O'Brien, T;Barry, F (2010) 'Mesenchymal Stem Cells Overexpressing Ephrin-B2 Rapidly Adopt an Early Endothelial Phenotype with Simultaneous Reduction of Osteogenic Potential'. Tissue Engineering Part A, 16 :2755-2768 [DOI] [Details]
	(2010)	'The healing of bony defects by cell-free collagen-based scaffolds compared to stem cell-seeded tissue engineered constructs' Lyons, FG;Al-Munajjed, AA;Kieran, SM;Toner, ME;Murphy, CM;Duffy, GP;O'Brien, FJ (2010) 'The healing of bony defects by cell-free collagen-based scaffolds compared to stem cell-seeded tissue engineered constructs'. Biomaterials, 31 :9232-9243 [DOI] [Details]
	(2009)	'Bone Marrow-Derived Mesenchymal Stem Cells Promote Angiogenic Processes in a Time- and Dose-Dependent Manner In Vitro' Duffy, GP;Ahsan, T;O'Brien, T;Barry, F;Nerem, RM (2009) 'Bone Marrow-Derived Mesenchymal Stem Cells Promote Angiogenic Processes in a Time- and Dose-Dependent Manner In Vitro'. Tissue Engineering Part A, 15 :2459-2470 [DOI] [Details]
	(2006)	'Gene-eluting stents: Comparison of adenoviral and adeno-associated viral gene delivery to the blood vessel wall in vivo' Sharif, F;Hynes, SO;McMahon, J;Cooney, R;Conroy, S;Dockery, P;Duffy, G;Daly, K;Crowley, J;Bartlett, JS;O'Brien, T (2006) 'Gene-eluting stents: Comparison of adenoviral and adeno-associated viral gene delivery to the blood vessel wall in vivo'. Human Gene Therapy, 17 :741-750 [Details]

Editorial

	Year	Publication
	(2017)	Tissue Engineered Solutions for Intracardiac Septal Defects: A Large Step Forward in an Unmet Clinical Need. Hameed, A;Duffy, GP;Hasan, B;Fatimi, SH (2017) Tissue Engineered Solutions for Intracardiac Septal Defects: A Large Step Forward in an Unmet Clinical Need. PHILADELPHIA: Editorial [DOI] [Details]
	(2015)	Form and function in regenerative medicine: introduction. O'Brien, FJ;Duffy, GP (2015) Form and function in regenerative medicine: introduction. HOBOKEN: Editorial [DOI] [Details]

Reviews

	Year	Publication
	(2016)	Nanomedicines for advanced cancer treatments: Transitioning towards responsive systems. van Elk, M;Murphy, BP;Eufrasio-da-Silva, T;O'Reilly, DP;Vermonden, T;Hennink, WE;Duffy, GP;Ruiz-Hernandez, E (2016) Nanomedicines for advanced cancer treatments: Transitioning towards responsive systems. AMSTERDAM: Reviews [DOI] [Details]
	(2015)	Drug and cell delivery for cardiac regeneration. Hastings, CL;Roche, ET;Ruiz-Hernandez, E;Schenke-Layland, K;Walsh, CJ;Duffy, GP (2015) Drug and cell delivery for cardiac regeneration. AMSTERDAM: Reviews [DOI] [Details]