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Medicine

Prof John Laffey

BSc, MB, Bch, BAO, MD, MA, FFARCSI

Contact Details

Professor Of Anaesthesia,
ANAESTHESIA
CLINICAL SCIENCE BUILDING
NUI
GALWAY
T: 5662 / 87-4608
E: john.laffey@nuigalway.ie
 
researcher
 

Biography

John Laffey is the Professor of Anaesthesia and Intensive Care Medicine at the School of Medicine of the National University of Ireland, and a Consultant in Anaesthesia and Intensive Care Medicine at Galway University Hospitals.

Research Interests

Professor Laffey’s major research interest is centred on investigation of the pathophysiology of, and development of therapeutic strategies for Acute Respiratory Distress Syndrome (ARDS), a devastating disease which causes severe respiratory failure in critically ill patients, and for which there are currently no specific therapies. More people die every year from ARDS than from other better known diseases such as HIV, Breast Cancer or Asthma.

Professor Laffey founded and lead the lung biology group at NUI Galway. His research group are currently conducting studies into the pathogenesis of ventilation and sepsis Acute Lung Injury. The current focus is on the investigation of the therapeutic potential of gene and stem cell based therapies for Acute Lung Injury. This work is being done in collaboration with colleagues from the Regenerative Medicine Institute (REMEDI) at NUI Galway. A long term focus of Professor Laffey’s work had been on determining the safety and therapeutic potential of hypercapnic acidosis in septic and inflammatory disease models of Acute Lung Injury.

Professor Laffey is a principal investigator at the National Centre for Biomedical Engineering Sciences, and a Clinical Trials Investigator at the HRB Clinical Research Facility at the National University of Ireland, Galway. The translation of promising therapeutic strategies emerging from these pre-clinical studies to the clinical setting, through the Clinical Research Facility, and in collaboration with the Irish Critical Care Trials group, is a priority.

Professor Laffey is co-principal investigator in the first investigator led multi-centre trial conducted in critically ill patients in Ireland. This study, termed the HARP-2 study, aims to determine whether statin therapy might help people suffering from ARDS.

Additional clinical research interests include the investigation of the utility of novel devices and technologies for management of the airway, and investigation of novel approaches to postoperative analgesia.

Peer Reviewed Journals

  Year Publication
(2021) 'Augmenting Critical Care Patient Monitoring Using Wearable Technology: Review of Usability and Human Factors'
Andrade E;Quinlan L;Harte R;Byrne D;Fallon E;Kelly M;Casey S;Kirrane F;O'Connor P;O'Hora D;Scully M;Laffey J;Pladys P;Beuchée A;ÓLaighin G; (2021) 'Augmenting Critical Care Patient Monitoring Using Wearable Technology: Review of Usability and Human Factors'. Jmir Human Factors, 8 (2) [DOI] [Details]
(2021) 'Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests'
De Marco Verissimo C;O'Brien C;López Corrales J;Dorey A;Cwiklinski K;Lalor R;Doyle JM;Field S;Masterson C;Ribes Martinez E;Hughes G;Bergin C;Walshe K;McNicholas B;Laffey JG;Dalton JP;Kerr C;Doyle S; (2021) 'Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests'. Epidemiology And Infection, 149 [DOI] [ARAN Link] [Details]
(2021) 'Sentiment analysis of user feedback on the HSE’s Covid-19 contact tracing app'
Rekanar, K., O’Keeffe, I.R., Buckley, S.Abbas, M., Beecham, S., Fitzgeral, B., Glynn, L,m Johnson, K., Laffey, J., McNicholas, G., O Connell, J., O Keefe, D., O Callaghan, M., Razzaq. R., Richardson, I., Simpkin A., Storni, C., Tsvyatkova, D., Walsh, J, Welsh, T., Buckley., J. (2021). (2021) 'Sentiment analysis of user feedback on the HSE’s Covid-19 contact tracing app'. Irish Journal Of Medical Science, [DOI] [Details]
(2021) 'A National Survey on use and perceived usefulness of the Irish COVID Tracker contact tracing App'
O'Callaghan ME, Abbas M, Buckley J, Fitzgerald B, Johnson K, Laffey J, McNicholas B, Nuseibeh B, O'Keeffe D, Beecham S, Razzaq A, Rekanar K, Richardson I, Simpkin A, O'Connell J, Storni C, Tsvyatkova D, Walsh J, Welsh T, Glynn LG (2021) 'A National Survey on use and perceived usefulness of the Irish COVID Tracker contact tracing App'. Journal of Medical Internet Research, [Details]
(2021) 'Best Practice Guidance for Digital Contact Tracing Apps: A Cross-Disciplinary Review of the Literature'
O'Connell J, Abbas M, Beecham S, Buckley J, Chochlov M, Fitzgerald B, Glynn L, Johnson K, Laffey J, McNicholas B, Nuseibeh B, O'Callaghan M, O'Keeffe I, Razzaq A, Rekanar K, Richardson I, Simpkin A, Storni C, Tsvyatkova D, Walsh J, Welsh T, O'Keeffe D. (2021). (2021) 'Best Practice Guidance for Digital Contact Tracing Apps: A Cross-Disciplinary Review of the Literature'. JMIR mHealth and uHealth (JMU), [DOI] [Details]
(2020) 'Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study'
Grasselli, G;Tonetti, T;Protti, A;Langer, T;Girardis, M;Bellani, G;Laffey, J;Carrafiello, G;Carsana, L;Rizzuto, C;Zanella, A;Scaravilli, V;Pizzilli, G;Grieco, DL;Di Meglio, L;de Pascale, G;Lanza, E;Monteduro, F;Zompatori, M;Filippini, C;Locatelli, F;Cecconi, M;Fumagalli, R;Nava, S;Vincent, JL;Antonelli, M;Slutsky, AS;Pesenti, A;Ranieri, VM (2020) 'Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study'. Lancet Respiratory Medicine, 8 :1201-1208 [DOI] [Details]
(2021) 'The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project'
Flynn J, O'Connor L, Hanlon M., Bellani, G., ,Contreras, M., Doherty A., Durand, H., Fallon, E., Gormley, G., Laffey, J., Molloy, GM, Sarma, K., Strepparava, M., Russo, S., Walsh, JC, McGuire, BM. (2021) 'The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project'. HRB Open Research, [Details]
(2019) 'Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study'
McNicholas, BA;Madotto, F;Pham, T;Rezoagli, E;Masterson, CH;Horie, S;Bellani, G;Brochard, L;Laffey, JG (2019) 'Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study'. European Respiratory Journal, 54 [DOI] [Details]
(2020) 'Compliance Phenotypes in Early Acute Respiratory Distress Syndrome before the COVID-19 Pandemic'
Panwar, R;Madotto, F;Laffey, JG;van Haren, FMP (2020) 'Compliance Phenotypes in Early Acute Respiratory Distress Syndrome before the COVID-19 Pandemic'. American Journal Of Respiratory And Critical Care Medicine, 202 :1244-1252 [DOI] [Details]
(2020) 'Awake prone positioning of hypoxaemic patients with COVID-19: protocol for a randomised controlled open-label superiority meta-trial'
Tavernier, E;McNicholas, B;Pavlov, I;Roca, O;Perez, Y;Laffey, J;Mirza, S;Cosgrave, D;Vines, D;Frat, JP;Ehrmann, S;Li, J (2020) 'Awake prone positioning of hypoxaemic patients with COVID-19: protocol for a randomised controlled open-label superiority meta-trial'. BMJ Open, 10 [DOI] [Details]
(2020) 'A national survey of attitudes to COVID-19 digital contact tracing in the Republic of Ireland'
O'Callaghan, ME;Buckley, J;Fitzgerald, B;Johnson, K;Laffey, J;McNicholas, B;Nuseibeh, B;O'Keeffe, D;O'Keeffe, I;Razzaq, A;Rekanar, K;Richardson, I;Simpkin, A;Abedin, J;Storni, C;Tsvyatkova, D;Walsh, J;Welsh, T;Glynn, L (2020) 'A national survey of attitudes to COVID-19 digital contact tracing in the Republic of Ireland'. Irish Journal of Medical Science, [DOI] [Details]
(2020) 'A national survey of attitudes to COVID-19 digital contact tracing in the Republic of Ireland'
O'Callaghan, ME,Buckley, J,Fitzgerald, B,Johnson, K,Laffey, J,McNicholas, B,Nuseibeh, B,O'Keeffe, D,O'Keeffe, I,Razzaq, A,Rekanar, K,Richardson, I,Simpkin, A,Abedin, J,Storni, C,Tsvyatkova, D,Walsh, J,Welsh, T,Glynn, L (2020) 'A national survey of attitudes to COVID-19 digital contact tracing in the Republic of Ireland'. Irish Journal Of Medical Science, [DOI] [Details]
(2020) 'Purified beta-glucans from the Shiitake mushroom ameliorates antibiotic-resistantKlebsiella pneumoniae-induced pulmonary sepsis'
Masterson, CH;Murphy, EJ;Gonzalez, H;Major, I;McCarthy, SD;O'Toole, D;Laffey, JG;Rowan, NJ (2020) 'Purified beta-glucans from the Shiitake mushroom ameliorates antibiotic-resistantKlebsiella pneumoniae-induced pulmonary sepsis'. Letters In Applied Microbiology, [DOI] [Details]
(2020) 'Purified beta-glucans from the Shiitake mushroom ameliorates antibiotic-resistantKlebsiella pneumoniae-induced pulmonary sepsis'
Masterson, CH,Murphy, EJ,Gonzalez, H,Major, I,McCarthy, SD,O'Toole, D,Laffey, JG,Rowan, NJ (2020) 'Purified beta-glucans from the Shiitake mushroom ameliorates antibiotic-resistantKlebsiella pneumoniae-induced pulmonary sepsis'. Letters In Applied Microbiology, [DOI] [Details]
(2020) 'The role of cells and their products in respiratory drug delivery: the past, present, and future'
Masterson, CH;McCarthy, SD;O'Toole, D;Laffey, JG (2020) 'The role of cells and their products in respiratory drug delivery: the past, present, and future'. Expert Opinion On Drug Delivery, [DOI] [Details]
(2020) 'A national survey of attitudes to COVID-19 digital contact tracing in the Republic of Ireland'
O’Callaghan, M., Buckley, J. Fitzgerald,B., Johnson,K., Laffey, J., McNicholas, B., Nuseibeh, B., O'Keeffe, D., O'Keeffe, I., Razzaq, A., Rekaner, A., Richardson, I., Simpkin, A., Storni, C., Tsvyatkova, D., Walsh, J., Welsh, T. Glynn, L (2020) 'A national survey of attitudes to COVID-19 digital contact tracing in the Republic of Ireland'. Irish Journal Of Medical Science, [DOI] [Details]
(2020) 'The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project'
Flynn, J; O'Connor, L; Hanlon, M; Bellani, G; Contreras, M; Doherty, A; Durand, H; Fallon, E; Gormley, C; Laffey, J; Molloy, G; Sarma, K; Strepparava, MG; Russo, S; Walsh, J; McGure, BE (2020) 'The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project'. HRB Open Research, [Details]
(2020) 'The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study'
McGuigan, PJ;Shankar-Hari, M;Harrison, DA;Laffey, JG;McAuley, DF (2020) 'The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study'. Critical Care, 24 [DOI] [Details]
(2020) 'Utility of Driving Pressure and Mechanical Power to Guide Protective Ventilator Settings in Two Cohorts of Adult and Pediatric Patients With Acute Respiratory Distress Syndrome: A Computational Investigation'
Saffaran, S;Das, A;Laffey, JG;Hardman, JG;Yehya, N;Bates, DG (2020) 'Utility of Driving Pressure and Mechanical Power to Guide Protective Ventilator Settings in Two Cohorts of Adult and Pediatric Patients With Acute Respiratory Distress Syndrome: A Computational Investigation'. Critical Care Medicine, 48 :1001-1008 [DOI] [Details]
(2020) 'Emerging pharmacological therapies for ARDS: COVID-19 and beyond'
Horie, S;McNicholas, B;Rezoagli, E;Pham, T;Curley, G;McAuley, D;O'Kane, C;Nichol, A;dos Santos, C;Rocco, PRM;Bellani, G;Laffey, JG (2020) 'Emerging pharmacological therapies for ARDS: COVID-19 and beyond'. Intensive Care Medicine, [DOI] [Details]
(2020) 'Novel Interface Designs for Patient Monitoring Applications in Critical Care Medicine: Human Factors Review'
Andrade E;Quinlan L;Harte R;Byrne D;Fallon E;Kelly M;Casey S;Kirrane F;O'Connor P;O'Hora D;Scully M;Laffey J;Pladys P;Beuchée A;ÓLaighin G; (2020) 'Novel Interface Designs for Patient Monitoring Applications in Critical Care Medicine: Human Factors Review'. Jmir Human Factors, 7 (3) [DOI] [Details]
(2020) 'Missed or delayed diagnosis of ARDS: a common and serious problem'
Bellani, G;Pham, T;Laffey, JG (2020) 'Missed or delayed diagnosis of ARDS: a common and serious problem'. Intensive Care Medicine, [DOI] [Details]
(2020) 'In vitro characterization of PrismaLung+: a novel ECCO2R device'
Hospach, I;Goldstein, J;Harenski, K;Laffey, JG;Pouchoulin, D;Raible, M;Votteler, S;Storr, M (2020) 'In vitro characterization of PrismaLung+: a novel ECCO2R device'. Intensive Care Medicine Experimental, 8 [DOI] [Details]
(2020) 'In vitro characterization of PrismaLung+: a novel ECCO2R device'
Hospach, I,Goldstein, J,Harenski, K,Laffey, JG,Pouchoulin, D,Raible, M,Votteler, S,Storr, M (2020) 'In vitro characterization of PrismaLung+: a novel ECCO2R device'. Intensive Care Medicine Experimental, 8 [DOI] [Details]
(2020) 'Challenges and solutions for addressing critical shortage of supply chain for personal and protective equipment (PPE) arising from Coronavirus disease (COVID19) pandemic - Case study from the Republic of Ireland'
Rowan, NJ;Laffey, JG (2020) 'Challenges and solutions for addressing critical shortage of supply chain for personal and protective equipment (PPE) arising from Coronavirus disease (COVID19) pandemic - Case study from the Republic of Ireland'. Science Of The Total Environment, 725 [DOI] [Details]
(2020) 'Challenges and solutions for addressing critical shortage of supply chain for personal and protective equipment (PPE) arising from Coronavirus disease (COVID19) pandemic - Case study from the Republic of Ireland'
Rowan, NJ,Laffey, JG (2020) 'Challenges and solutions for addressing critical shortage of supply chain for personal and protective equipment (PPE) arising from Coronavirus disease (COVID19) pandemic - Case study from the Republic of Ireland'. Science Of The Total Environment, 725 [DOI] [Details]
(2020) 'Patterns of Use of Adjunctive Therapies in Patients With Early Moderate to Severe ARDS Insights From the LUNG SAFE Study'
Duggal, A;Rezoagli, E;Pham, T;McNicholas, BA;Fan, E;Bellani, G;Rubenfeld, G;Pesenti, AM;Laffey, JG (2020) 'Patterns of Use of Adjunctive Therapies in Patients With Early Moderate to Severe ARDS Insights From the LUNG SAFE Study'. Chest, 157 :1497-1505 [DOI] [Details]
(2020) 'S-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in -vitro immunomodulatory and pulmonary cytoprotective effects ? Implications for coronavirus disease (COVID-19) immunotherapies'
Murphy, EJ;Masterson, C;Rezoagli, E;O'Toole, D;Major, I;Stack, GD;Lynch, M;Laffey, JG;Rowan, NJ (2020) 'S-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in -vitro immunomodulatory and pulmonary cytoprotective effects ? Implications for coronavirus disease (COVID-19) immunotherapies'. Science Of The Total Environment, 732 [DOI] [Details]
(2020) 'S-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in -vitro immunomodulatory and pulmonary cytoprotective effects ? Implications for coronavirus disease (COVID-19) immunotherapies'
Murphy, EJ,Masterson, C,Rezoagli, E,O'Toole, D,Major, I,Stack, GD,Lynch, M,Laffey, JG,Rowan, NJ (2020) 'S-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in -vitro immunomodulatory and pulmonary cytoprotective effects ? Implications for coronavirus disease (COVID-19) immunotherapies'. Science Of The Total Environment, 732 [DOI] [Details]
(2017) 'Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome'
Curley, GF;Jerkic, M;Dixon, S;Hogan, G;Masterson, C;O'Toole, D;Devaney, J;Laffey, JG (2017) 'Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome'. Critical Care Medicine, 45 :202-212 [DOI] [Details]
(2017) 'Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome'
Curley, GF,Jerkic, M,Dixon, S,Hogan, G,Masterson, C,O'Toole, D,Devaney, J,Laffey, JG (2017) 'Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome'. Critical Care Medicine, 45 :202-212 [DOI] [Details]
(2020) 'Lung-kidney cross-talk in the critically ill: insights from the Lung Safe study'
Rezoagli, E;McNicholas, B;Pham, T;Bellani, G;Laffey, JG (2020) 'Lung-kidney cross-talk in the critically ill: insights from the Lung Safe study'. Intensive Care Medicine, [DOI] [Details]
(2020) 'Umbilical cord-derived CD362(+) mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy'
Horie, S;Masterson, C;Brady, J;Loftus, P;Horan, E;O'Flynn, L;Elliman, S;Barry, F;O'Brien, T;Laffey, JG;O'Toole, D (2020) 'Umbilical cord-derived CD362(+) mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy'. Stem Cell Research & Therapy, 11 [DOI] [Details]
(2020) 'Umbilical cord-derived CD362(+) mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy'
Horie, S,Masterson, C,Brady, J,Loftus, P,Horan, E,O'Flynn, L,Elliman, S,Barry, F,O'Brien, T,Laffey, JG,O'Toole, D (2020) 'Umbilical cord-derived CD362(+) mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy'. Stem Cell Research & Therapy, 11 [DOI] [Details]
(2020) 'Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study'
Madotto, F;Rezoagli, E;Pham, T;Schmidt, M;McNicholas, B;Protti, A;Panwar, R;Bellani, G;Fan, E;van Haren, F;Brochard, L;Laffey, JG (2020) 'Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study'. Critical Care, 24 [DOI] [Details]
(2020) 'Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats'
Jerkic, M;Gagnon, S;Rabani, R;Ward-Able, T;Masterson, C;Otulakowski, G;Curley, GF;Marshall, J;Kavanagh, BP;Laffey, JG (2020) 'Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats'. Anesthesiology, 132 :140-154 [DOI] [Details]
(2020) 'Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism'
Horie, S;Gaynard, S;Murphy, M;Barry, F;Scully, M;O'Toole, D;Laffey, JG (2020) 'Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism'. Intensive Care Medicine Experimental, 8 [DOI] [Details]
(2020) 'Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism'
Horie, S,Gaynard, S,Murphy, M,Barry, F,Scully, M,O'Toole, D,Laffey, JG (2020) 'Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism'. Intensive Care Medicine Experimental, 8 [DOI] [Details]
(2019) 'Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates'
McCarthy, SD;Horgan, E;Ali, A;Masterson, C;Laffey, JG;MacLoughlin, R;O'Toole, D (2019) 'Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates'. Journal Of Aerosol Medicine And Pulmonary Drug Delivery, [DOI] [Details]
(2019) 'Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates'
McCarthy, SD,Horgan, E,Ali, A,Masterson, C,Laffey, JG,MacLoughlin, R,O'Toole, D (2019) 'Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates'. Journal Of Aerosol Medicine And Pulmonary Drug Delivery, [DOI] [Details]
(2019) 'Accuracy of pediatric cricothyroid membrane identification by digital palpation and implications for emergency front of neck access'
Fennessy, P;Walsh, B;Laffey, JG;McCarthy, KF;McCaul, CL (2019) 'Accuracy of pediatric cricothyroid membrane identification by digital palpation and implications for emergency front of neck access'. Pediatric Anesthesia, [DOI] [Details]
(2019) 'Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study'
McNicholas, BA;Rezoagli, E;Pham, T;Madotto, F;Guiard, E;Fanelli, V;Bellani, G;Griffin, MD;Ranieri, M;Laffey, JG (2019) 'Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study'. Critical Care Medicine, 47 :1216-1225 [DOI] [Details]
(2019) 'Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design'
Goligher, EC;Combes, A;Brodie, D;Ferguson, ND;Pesenti, AM;Ranieri, VM;Slutsky, AS;Beale, R;Brochard, L;Chiche, JD;Fan, E;de Backer, D;Francois, G;Laffey, J;Mercat, A;McAuley, DF;Muller, T;Quintel, M;Vincent, JL;Taccone, FS;Peperstraete, H;Morimont, P;Schmidt, M;Levy, B;Diehl, JL;Guervilly, C;Capelier, G;Vieillard-Baron, A;Messika, J;Karagiannidis, C;Moerer, O;Urbino, R;Antonelli, M;Mojoli, F;Alessandri, F;Grasselli, G;Donker, D;Ferrer, R;Mancebo, J;Fanelli, V;Pham, T (2019) 'Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design'. Intensive Care Medicine, 45 :1219-1230 [DOI] [Details]
(2019) 'Is Activity Tracker-Measured Ambulation an Accurate and Reliable Determinant of Postoperative Quality of Recovery? A Prospective Cohort Validation Study'
Massouh, F;Martin, R;Chan, B;Ma, JL;Patel, V;Geary, MP;Laffey, JG;Wijeysundera, DN;Abdallah, FW (2019) 'Is Activity Tracker-Measured Ambulation an Accurate and Reliable Determinant of Postoperative Quality of Recovery? A Prospective Cohort Validation Study'. Anesthesia And Analgesia, 129 :1144-1152 [DOI] [Details]
(2019) 'Extracellular Vesicles from Interferon-gamma-primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli-induced Acute Lung Injury in Rats'
Varkouhi, AK,Jerkic, M,Ormesher, L,Gagnon, S,Goyal, S,Rabani, R,Masterson, C,Spring, C,Chen, PZ,Gu, FX,dos Santos, CC,Curley, GF,Laffey, JG (2019) 'Extracellular Vesicles from Interferon-gamma-primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli-induced Acute Lung Injury in Rats'. Anesthesiology, 130 :778-790 [DOI] [Details]
(2019) 'Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III)'
Juffermans, NP;Schultz, M;Bos, LD;Penuelas, O;Laffey, J;Lorente, JA (2019) 'Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III)'. Intensive Care Medicine Experimental, 7 [DOI] [Details]
(2019) 'Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III)'
Juffermans, NP,Schultz, M,Bos, LD,Penuelas, O,Laffey, J,Lorente, JA (2019) 'Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III)'. Intensive Care Medicine Experimental, 7 [DOI] [Details]
(2003) 'Optimizing the dose of intrathecal morphine in older patients undergoing hip arthroplasty'
Murphy, PM;Stack, D;Kinirons, B;Laffey, JG (2003) 'Optimizing the dose of intrathecal morphine in older patients undergoing hip arthroplasty'. Anesthesia And Analgesia, 97 :1709-1715 [DOI] [Details]
(2004) 'Maternal brain death: medical, ethical and legal issues'
Lane, A;Westbrook, A;Grady, D;O'Connor, R;Counihan, TJ;Marsh, B;Laffey, JG (2004) 'Maternal brain death: medical, ethical and legal issues'. Intensive Care Medicine, 30 :1484-1486 [DOI] [Details]
(2005) 'Hypercapnic acidosis does not modulate the severity of bacterial pneumonia-induced lung injury'
O'Croinin, DF;Hopkins, NO;Moore, MM;Boylan, JF;McLoughlin, P;Laffey, JG (2005) 'Hypercapnic acidosis does not modulate the severity of bacterial pneumonia-induced lung injury'. Critical Care Medicine, 33 :2606-2612 [DOI] [Details]
(2006) 'Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection'
Hopkins, N;Gunning, Y;O'Croinin, DF;Laffey, J;McLoughlin, P (2006) 'Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection'. Journal Of Pathology, 209 :198-205 [DOI] [Details]
(2007) 'Transversus abdominis plane block: A cadaveric and radiological evaluation'
McDonnell, JG;O'Donnell, BD;Farrell, T;Gough, N;Tuite, D;Power, C;Laffey, JG (2007) 'Transversus abdominis plane block: A cadaveric and radiological evaluation'. Regional Anesthesia And Pain Medicine, 32 :399-404 [DOI] [Details]
(2007) 'Recovery of older patients undergoing ambulatory anaesthesia with isoflurane or sevoflurane'
Mahajan, VA;Ni Chonghaile, M;Bokhari, SA;Harte, BH;Flynn, NM;Laffey, JG (2007) 'Recovery of older patients undergoing ambulatory anaesthesia with isoflurane or sevoflurane'. European Journal Of Anaesthesiology, 24 :505-510 [DOI] [Details]
(2007) 'A comparison of direct and indirect laryngoscopes and the ILMA in novice users: a manikin study'
Maharaj, CH;McDonnell, JG;Harte, BH;Laffey, JG (2007) 'A comparison of direct and indirect laryngoscopes and the ILMA in novice users: a manikin study'. Anaesthesia, 62 :1161-1166 [DOI] [Details]
(2007) 'Endotracheal intubation in patients with cervical spine immobilization - A comparison of Macintosh and Airtraq laryngoscopes'
Maharaj, CH;Buckley, E;Harte, BH;Laffey, JG (2007) 'Endotracheal intubation in patients with cervical spine immobilization - A comparison of Macintosh and Airtraq laryngoscopes'. Anesthesiology, 107 :53-59 [Details]
(2008) 'The Transversus Abdominis Plane Block Provides Effective Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy'
Carney, J;McDonnell, JG;Ochana, A;Bhinder, R;Laffey, JG (2008) 'The Transversus Abdominis Plane Block Provides Effective Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy'. Anesthesia And Analgesia, 107 :2056-2060 [DOI] [Details]
(2008) 'Hypercapnic acidosis attenuates severe acute bacterial pneumonia-induced lung injury by a neutrophil-independent mechanism'
Chonghaile, MN;Higgins, BD;Costello, JF;Laffey, JG (2008) 'Hypercapnic acidosis attenuates severe acute bacterial pneumonia-induced lung injury by a neutrophil-independent mechanism'. Critical Care Medicine, 36 :3135-3144 [DOI] [Details]
(2008) 'The analgesic efficacy of transversus abdominis plane block after cesarean delivery: A randomized controlled trial'
McDonnell, JG;Curley, G;Carney, J;Benton, A;Costello, J;Maharaj, CH;Laffey, JG (2008) 'The analgesic efficacy of transversus abdominis plane block after cesarean delivery: A randomized controlled trial'. Anesthesia And Analgesia, 106 :186-191 [DOI] [Details]
(2008) 'Sevoflurane and the feto-placental vasculature: The role of nitric oxide and vasoactive eicosanoids'
Farragher, R;Maharaj, CH;Higgins, BD;Crowe, S;Burke, P;Laffey, CD;Flynn, NM;Laffey, JG (2008) 'Sevoflurane and the feto-placental vasculature: The role of nitric oxide and vasoactive eicosanoids'. Anesthesia And Analgesia, 107 :171-177 [DOI] [Details]
(2008) 'Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury'
O'Croinin, DF;Nichol, AD;Hopkins, N;Boylan, J;O'Brien, S;O'Connor, C;Laffey, JG;McLoughlin, P (2008) 'Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury'. Critical Care Medicine, 36 :2128-2135 [DOI] [Details]
(2008) 'Fluid dynamics of gas exchange in high-frequency oscillatory ventilation: In vitro investigations in idealized and anatomically realistic airway bifurcation models'
Heraty, KB;Laffey, JG;Quinlan, NJ (2008) 'Fluid dynamics of gas exchange in high-frequency oscillatory ventilation: In vitro investigations in idealized and anatomically realistic airway bifurcation models'. Annals Of Biomedical Engineering, 36 :1856-1869 [DOI] [Details]
(2009) 'Optimized Aerosol Delivery to a Mechanically Ventilated Rodent'
MacLoughlin, RJ;Higgins, BD;Laffey, JG;O'Brien, T (2009) 'Optimized Aerosol Delivery to a Mechanically Ventilated Rodent'. Journal Of Aerosol Medicine And Pulmonary Drug Delivery, 22 :323-332 [DOI] [Details]
(2009) 'Differential Effects of Buffered Hypercapnia versus Hypercapnic Acidosis on Shock and Lung Injury Induced by Systemic Sepsis'
Higgins, BD;Costello, J;Contreras, M;Hassett, P;O'Toole, D;Laffey, JG (2009) 'Differential Effects of Buffered Hypercapnia versus Hypercapnic Acidosis on Shock and Lung Injury Induced by Systemic Sepsis'. Anesthesiology, 111 :1317-1326 [Details]
(2009) 'Effects and mechanisms of action of sildenafil citrate in human chorionic arteries'
Maharaj, CH;O'Toole, D;Lynch, T;Carney, J;Jarman, J;Higgins, BD;Morrison, JJ;Laffey, JG (2009) 'Effects and mechanisms of action of sildenafil citrate in human chorionic arteries'. Reproductive Biology And Endocrinology, 7 [DOI] [Details]
(2009) 'Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis'
Nichol, AD;O'Cronin, DF;Howell, K;Naughton, F;O'Brien, S;Boylan, J;O'Connor, C;O'Toole, D;Laffey, JG;McLoughlin, P (2009) 'Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis'. Critical Care Medicine, 37 :2953-2961 [DOI] [Details]
(2010) 'Investigation of critical inter-related factors affecting the efficacy of pulsed light for inactivating clinically relevant bacterial pathogens'
Farrell, HP;Garvey, M;Cormican, M;Laffey, JG;Rowan, NJ (2010) 'Investigation of critical inter-related factors affecting the efficacy of pulsed light for inactivating clinically relevant bacterial pathogens'. Journal Of Applied Microbiology, 108 :1494-1508 [DOI] [Details]
(2010) 'Ipsilateral Transversus Abdominis Plane Block Provides Effective Analgesia After Appendectomy in Children: A Randomized Controlled Trial'
Carney, J;Finnerty, O;Rauf, J;Curley, G;McDonnell, JG;Laffey, JG (2010) 'Ipsilateral Transversus Abdominis Plane Block Provides Effective Analgesia After Appendectomy in Children: A Randomized Controlled Trial'. Anesthesia And Analgesia, 111 :998-1003 [DOI] [Details]
(2011) 'Studies on the spread of local anaesthetic solution in transversus abdominis plane blocks'
Carney, J;Finnerty, O;Rauf, J;Bergin, D;Laffey, JG;Mc Donnell, JG (2011) 'Studies on the spread of local anaesthetic solution in transversus abdominis plane blocks'. Anaesthesia, 66 :1023-1030 [DOI] [Details]
(2011) 'Can 'Permissive' Hypercapnia Modulate the Severity of Sepsis-induced ALI/ARDS?'
Curley, G;Hayes, M;Laffey, JG (2011) 'Can 'Permissive' Hypercapnia Modulate the Severity of Sepsis-induced ALI/ARDS?'. Annual Update In Intensive Care And Emergency Medicine 2011, :174-187 [Details]
(2011) 'Comparison of three cuffed emergency percutaneous cricothyroidotomy devices to conventional surgical cricothyroidotomy in a porcine model'
Murphy, C;Rooney, SJ;Maharaj, CH;Laffey, JG;Harte, BH (2011) 'Comparison of three cuffed emergency percutaneous cricothyroidotomy devices to conventional surgical cricothyroidotomy in a porcine model'. British Journal Of Anaesthesia, 106 :57-64 [DOI] [Details]
(2011) 'Determination of the utility of the Intubation Difficulty Scale for use with indirect laryngoscopes'
McElwain, J;Simpkin, A;Newell, J;Laffey, JG (2011) 'Determination of the utility of the Intubation Difficulty Scale for use with indirect laryngoscopes'. Anaesthesia, 66 :1127-1133 [DOI] [Details]
(2011) 'Studies on the relationship between pulsed UV light irradiation and the simultaneous occurrence of molecular and cellular damage in clinically-relevant Candida albicans'
Farrell, H;Hayes, J;Laffey, J;Rowan, N (2011) 'Studies on the relationship between pulsed UV light irradiation and the simultaneous occurrence of molecular and cellular damage in clinically-relevant Candida albicans'. Journal Of Microbiological Methods, 84 :317-326 [DOI] [Details]
(2011) 'Determination of the utility of the Intubation Difficulty Scale for use with indirect laryngoscopes'
McElwain J, Simpkin A, Newell J, Laffey JG. (2011) 'Determination of the utility of the Intubation Difficulty Scale for use with indirect laryngoscopes'. Anaesthesia, [Details]
(2011) 'Can 'Permissive' Hypercapnia Modulate the Severity of Sepsis-induced ALI/ARDS?'
Curley, G,Hayes, M,Laffey, JG,Vincent, JL (2011) 'Can 'Permissive' Hypercapnia Modulate the Severity of Sepsis-induced ALI/ARDS?'. Annual Update In Intensive Care And Emergency Medicine 2011, :174-187 [Details]
(2011) 'Stellate ganglion blockade for analgesia following upper limb surgery'
McDonnell, JG;Finnerty, O;Laffey, JG (2011) 'Stellate ganglion blockade for analgesia following upper limb surgery'. Anaesthesia, 66 :611-614 [DOI] [Details]
(2011) 'Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat'
Curley, GF;Contreras, M;Higgins, B;O'Kane, C;McAuley, DF;O'Toole, D;Laffey, JG (2011) 'Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat'. Anesthesiology, 115 :1022-1032 [DOI] [Details]
(2012) 'Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial'
McAuley, DF;Laffey, JG;O'Kane, CM;Cross, M;Perkins, GD;Murphy, L;McNally, C;Crealey, G;Stevenson, M (2012) 'Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial'. Trials, 13 [DOI] [Details]
(2012) 'Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat'
Curley, GF;Hayes, M;Ansari, B;Shaw, G;Ryan, A;Barry, F;O'Brien, T;O'Toole, D;Laffey, JG (2012) 'Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat'. Thorax, 67 :496-501 [DOI] [Details]
(2012) 'Studies on the pathogenesis and survival of different culture forms of Listeria monocytogenes to pulsed UV-light irradiation after exposure to mild-food processing stresses'
Bradley, D;McNeil, B;Laffey, JG;Rowan, NJ (2012) 'Studies on the pathogenesis and survival of different culture forms of Listeria monocytogenes to pulsed UV-light irradiation after exposure to mild-food processing stresses'. Food Microbiology, 30 :330-339 [DOI] [Details]
(2012) 'Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO2 Sensing and Signaling'
Oliver, KM;Lenihan, CR;Bruning, U;Cheong, A;Laffey, JG;McLoughlin, P;Taylor, CT;Cummins, EP (2012) 'Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO2 Sensing and Signaling'. Journal Of Biological Chemistry, 287 :14004-14011 [DOI] [Details]
(2012) 'Relationship between growth of food-spoilage yeast in high-sugar environments and sensitivity to high-intensity pulsed UV light irradiation'
Hayes, JC;Laffey, JG;McNeil, B;Rowan, NJ (2012) 'Relationship between growth of food-spoilage yeast in high-sugar environments and sensitivity to high-intensity pulsed UV light irradiation'. International Journal Of Food Science And Technology, 47 :1925-1934 [DOI] [Details]
(2013) 'Inhibition of pulmonary nuclear factor kappa-B decreases the severity of acute Escherichia coli pneumonia but worsens prolonged pneumonia'
Devaney, J;Curley, GF;Hayes, M;Masterson, C;Ansari, B;O'Brien, T;O'Toole, D;Laffey, JG (2013) 'Inhibition of pulmonary nuclear factor kappa-B decreases the severity of acute Escherichia coli pneumonia but worsens prolonged pneumonia'. Critical Care, 17 [DOI] [Details]
(2013) 'Comparison of the Baska (R) mask with the single-use laryngeal mask airway in low-risk female patients undergoing ambulatory surgery'
Alexiev, V;Ochana, A;Abdelrahman, D;Coyne, J;McDonnell, JG;O'Toole, DP;Neligan, P;Laffey, JG (2013) 'Comparison of the Baska (R) mask with the single-use laryngeal mask airway in low-risk female patients undergoing ambulatory surgery'. Anaesthesia, 68 :1026-1032 [DOI] [Details]
(2014) 'Simvastatin in the Acute Respiratory Distress Syndrome'
McAuley, DF,Laffey, JG,O'Kane, CM,Perkins, GD,Mullan, B,Trinder, TJ,Johnston, P,Hopkins, PA,Johnston, AJ,McDowell, C,McNally, C,HARP-2 Investigators,Irish Critical Care Trials Grp (2014) 'Simvastatin in the Acute Respiratory Distress Syndrome'. New England Journal Of Medicine, 371 :1695-1703 [DOI] [Details]
(2016) 'Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study'
McDonnell, MJ,Aliberti, S,Goeminne, PC,Restrepo, MI,Finch, S,Pesci, A,Dupont, LJ,Fardon, TC,Wilson, R,Loebinger, MR,Skrbic, D,Obradovic, D,De Soyza, A,Ward, C,Laffey, JG,Rutherford, RM,Chalmers, JD (2016) 'Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study'. Lancet Respiratory Medicine, 4 :969-979 [DOI] [Details]
(2017) 'Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study'
Laffey, JG,Madotto, F,Bellani, G,Pham, T,Fan, E,Brochard, L,Amin, P,Arabi, Y,Bajwa, EK,Bruhn, A,Cerny, V,Clarkson, K,Heunks, L,Kurahashi, K,Laake, JH,Lorente, JA,McNamee, L,Nin, N,Palo, JE,Piquilloud, L,Qiu, HB,Ignacio, J,Jimenez, S,Esteban, A,McAuley, DF,van Haren, F,Ranieri, M,Rubenfeld, G,Wrigge, H,Slutsky, AS,Pesenti, A,LUNG SAFE Investigators,ESICM Trials Grp (2017) 'Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study'. Lancet Respiratory Medicine, 5 :627-638 [DOI] [Details]
(2018) 'Using Activity Trackers to Quantify Postpartum Ambulation A Prospective Observational Study of Ambulation after Regional Anesthesia and Analgesia Interventions'
Ma, J,Martin, R,Chan, B,Gofeld, M,Geary, MP,Laffey, JG,Abdallah, FW (2018) 'Using Activity Trackers to Quantify Postpartum Ambulation A Prospective Observational Study of Ambulation after Regional Anesthesia and Analgesia Interventions'. Anesthesiology, 128 :598-608 [DOI] [Details]
(2018) 'Should continuous rather than single-injection interscalene block be routinely offered for major shoulder surgery? A meta-analysis of the analgesic and side-effects profiles'
Vorobeichik, L,Brull, R,Bowry, R,Laffey, JG,Abdallah, FW (2018) 'Should continuous rather than single-injection interscalene block be routinely offered for major shoulder surgery? A meta-analysis of the analgesic and side-effects profiles'. British Journal Of Anaesthesia, 120 :679-692 [DOI] [Details]
(2018) 'Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database'
Cortegiani, A,Madotto, F,Gregoretti, C,Bellani, G,Laffey, JG,Pham, T,Van Haren, F,Giarratano, A,Antonelli, M,Pesenti, A,Grasselli, G,LUNG SAFE Investigators ESICM T (2018) 'Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database'. Critical care (London, England), 22 [DOI] [Details]
(2018) 'Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study'
Madotto, F,Pham, T,Bellani, G,Bos, LD,Simonis, FD,Fan, E,Artigas, A,Brochard, L,Schultz, MJ,Laffey, JG,Lung Safe Investigators the ESICM (2018) 'Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study'. Intensive Care Medicine, 44 :564-577 [DOI] [Details]
(2018) 'Syndecan-2-positive, Bone Marrow-derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats'
Masterson, C,Devaney, J,Horie, S,O'Flynn, L,Deedigan, L,Elliman, S,Barry, F,O'Brien, T,O'Toole, D,Laffey, JG (2018) 'Syndecan-2-positive, Bone Marrow-derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats'. Anesthesiology, 129 :502-516 [DOI] [Details]
(2018) 'Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial'
Calfee, CS,Delucchi, KL,Sinha, P,Matthay, MA,Hackett, J,Shankar-Hari, M,McDowell, C,Laffey, JG,O'Kane, CM,McAuley, DF,Irish Critical Care Trials Grp (2018) 'Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial'. Lancet Respiratory Medicine, 6 :691-698 [DOI] [Details]
(2018) 'Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries'
Abe, T,Madotto, F,Pham, T,Nagata, I,Uchida, M,Tamiya, N,Kurahashi, K,Bellani, G,Laffey, JG,LUNG-SAFE Investigators,ESICM Trials Grp (2018) 'Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries'. Critical care (London, England), 22 [DOI] [Details]
(2018) 'Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database'
Boyle, AJ,Madotto, F,Laffey, JG,Bellani, G,Pham, T,Pesenti, A,Thompson, BT,O'Kane, CM,Deane, AM,McAuley, DF,LUNG Safe Investigators,ESICM Trials Grp (2018) 'Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database'. Critical care (London, England), 22 [DOI] [Details]
(2018) 'Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury'
Shologu N, Scully M, Laffey JG, O'Toole D. (2018) 'Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury'. International Journal Of Molecular Sciences, [Details]
(2018) 'A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk'
McDonnell MJ, O'Toole D, Ward C, Pearson JP, Lord JL, De Soyza A, Loebinger M, Chalmers JD, Laffey JG, Rutherford RM. (2018) 'A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk'. Respiratory Medicine, [Details]
(2018) 'Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (vol 42, pg 1865, 2016)'
Laffey, JG;Bellani, G;Pham, T;Fan, E;Madotto, F;Bajwa, EK;Brochard, L;Clarkson, K;Esteban, A;Gattinoni, L;van Haren, F;Heunks, LM;Kurahashi, K;Laake, JH;Larsson, A;McAuley, DF;McNamee, L;Nin, N;Qiu, HB;Ranieri, M;Rubenfeld, GD;Thompson, BT;Wrigge, H;Slutsky, AS;Pesenti, A (2018) 'Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (vol 42, pg 1865, 2016)'. Intensive Care Medicine, 44 :157-165 [DOI] [Details]
(2019) 'Extracellular Vesicles from Interferon-gamma-primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli-induced Acute Lung Injury in Rats'
Varkouhi, AK;Jerkic, M;Ormesher, L;Gagnon, S;Goyal, S;Rabani, R;Masterson, C;Spring, C;Chen, PZ;Gu, FX;dos Santos, CC;Curley, GF;Laffey, JG (2019) 'Extracellular Vesicles from Interferon-gamma-primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli-induced Acute Lung Injury in Rats'. Anesthesiology, 130 :778-790 [DOI] [Details]
(2019) 'Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study'
Combes, A;Fanelli, V;Pham, T;Ranieri, VM;Goligher, EC;Brodie, D;Pesenti, A;Beale, R;Brochard, L;Chiche, JD;Fan, E;de Backer, D;Francois, G;Ferguson, N;Laffey, J;Mercat, A;McAuley, DF;Muller, T;Quintel, M;Vincent, JL;Taccone, FS;Peperstraete, H;Morimont, P;Schmidt, M;Levy, B;Diehl, JL;Guervilly, C;Capelier, G;Vieillard-Baron, A;Messika, J;Karagiannidis, C;Moerer, O;Urbino, R;Antonelli, M;Mojoli, F;Alessandri, F;Grasselli, G;Donker, D;Ferrer, R;Mancebo, J;Slutsky, AS (2019) 'Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study'. Intensive Care Medicine, 45 :592-600 [DOI] [Details]
(2019) 'Identification and Modulation of Microenvironment Is Crucial for Effective Mesenchymal Stromal Cell Therapy in Acute Lung Injury'
Islam, D;Huang, YB;Fanelli, V;Delsedime, L;Wu, SL;Khang, JL;Han, B;Grassi, A;Li, MS;Xu, YH;Luo, A;Wu, JF;Liu, XQ;McKillop, M;Medin, J;Qiu, HB;Zhong, NS;Liu, MY;Laffey, J;Li, YM;Zhang, HB (2019) 'Identification and Modulation of Microenvironment Is Crucial for Effective Mesenchymal Stromal Cell Therapy in Acute Lung Injury'. American Journal Of Respiratory And Critical Care Medicine, 199 :1214-1224 [DOI] [Details]
(2017) 'Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome'
Curley, G. F.,Jerkic, M.,Dixon, S.,Hogan, G.,Masterson, C.,O'Toole, D.,Devaney, J.,Laffey, J. G. (2017) 'Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome'. Crit Care Med, 45 (22) [Details]
(2017) 'Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study'
Bellani, G.,Laffey, J. G.,Pham, T.,Madotto, F.,Fan, E.,Brochard, L.,Esteban, A.,Gattinoni, L.,Bumbasirevic, V.,Piquilloud, L.,van Haren, F.,Larsson, A.,McAuley, D. F.,Bauer, P. R.,Arabi, Y. M.,Ranieri, M.,Antonelli, M.,Rubenfeld, G. D.,Thompson, B. T.,Wrigge, H.,Slutsky, A. S.,Pesenti, A. (2017) 'Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study'. Am J Respir Crit Care Med, 195 (11):67-77 [Details]
(2017) 'Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial'
Agus, A,Hulme, C,Verghis, RM,McDowell, C,Jackson, C,O'Kane, CM,Laffey, JG,McAuley, DF (2017) 'Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial'. Critical care (London, England), 21 [DOI] [Details]
(2017) 'Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial'
Bluth, T.,Teichmann, R.,Kiss, T.,Bobek, I.,Canet, J.,Cinnella, G.,De Baerdemaeker, L.,Gregoretti, C.,Hedenstierna, G.,Hemmes, S. N.,Hiesmayr, M.,Hollmann, M. W.,Jaber, S.,Laffey, J. G.,Licker, M. J.,Markstaller, K.,Matot, I.,Muller, G.,Mills, G. H.,Mulier, J. P.,Putensen, C.,Rossaint, R.,Schmitt, J.,Senturk, M.,Serpa Neto, A.,Severgnini, P.,Sprung, J.,Vidal Melo, M. F.,Wrigge, H.,Schultz, M. J.,Pelosi, P.,Gama de Abreu, M. (2017) 'Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial'. Trials, 18 (11) [Details]
(2017) 'Fifty Years of Research in ARDS. Insight into Acute Respiratory Distress Syndrome. From Models to Patients'
Laffey, J. G.,Kavanagh, B. P. (2017) 'Fifty Years of Research in ARDS. Insight into Acute Respiratory Distress Syndrome. From Models to Patients'. Am J Respir Crit Care Med, 196 (11):18-28 [Details]
(2017) 'Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study'
Laffey, J. G.,Madotto, F.,Bellani, G.,Pham, T.,Fan, E.,Brochard, L.,Amin, P.,Arabi, Y.,Bajwa, E. K.,Bruhn, A.,Cerny, V.,Clarkson, K.,Heunks, L.,Kurahashi, K.,Laake, J. H.,Lorente, J. A.,McNamee, L.,Nin, N.,Palo, J. E.,Piquilloud, L.,Qiu, H.,Jimenez, J. I. S.,Esteban, A.,McAuley, D. F.,van Haren, F.,Ranieri, M.,Rubenfeld, G.,Wrigge, H.,Slutsky, A. S.,Pesenti, A. (2017) 'Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study'. Lancet Respir Med, 5 (88):627-638 [Details]
(2017) 'Fifty Years of Research in ARDS. Cell-based Therapy for Acute Respiratory Distress Syndrome. Biology and Potential Therapeutic Value'
Laffey, J. G.,Matthay, M. A. (2017) 'Fifty Years of Research in ARDS. Cell-based Therapy for Acute Respiratory Distress Syndrome. Biology and Potential Therapeutic Value'. Am J Respir Crit Care Med, 196 (33):266-273 [Details]
(2017) 'Continued under-recognition of acute respiratory distress syndrome after the Berlin definition: what is the solution?'
Laffey, J. G.,Pham, T.,Bellani, G. (2017) 'Continued under-recognition of acute respiratory distress syndrome after the Berlin definition: what is the solution?'. Curr Opin Crit Care, 23 (11):10-17 [Details]
(2017) 'Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials'
Nagendran, M.,McAuley, D. F.,Kruger, P. S.,Papazian, L.,Truwit, J. D.,Laffey, J. G.,Thompson, B. T.,Clarke, M.,Gordon, A. C. (2017) 'Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials'. Intensive Care Med, 43 (55):663-671 [Details]
(2017) 'A comparison of videolaryngoscopes for tracheal intubation in predicted difficult airway: a feasibility study'
Vargas, M.,Pastore, A.,Aloj, F.,Laffey, J. G.,Servillo, G. (2017) 'A comparison of videolaryngoscopes for tracheal intubation in predicted difficult airway: a feasibility study'. BMC Anesthesiol, 17 (11) [Details]
(2016) 'Effects and Mechanisms by Which Hypercapnic Acidosis Inhibits Sepsis-Induced Canonical Nuclear Factor-kappa B Signaling in the Lung'
Masterson, C,O'Toole, D,Leo, A,McHale, P,Horie, S,Devaney, J,Laffey, JG (2016) 'Effects and Mechanisms by Which Hypercapnic Acidosis Inhibits Sepsis-Induced Canonical Nuclear Factor-kappa B Signaling in the Lung'. Critical Care Medicine, 44 :207-217 [DOI] [Details]
(2016) 'Stem cell therapy for acute respiratory distress syndrome: a promising future?'
Horie, S.,Masterson, C.,Devaney, J.,Laffey, J. G. (2016) 'Stem cell therapy for acute respiratory distress syndrome: a promising future?'. Curr Opin Crit Care, 22 (11):14-20 [Details]
(2016) 'Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study'
Laffey, JG,Bellani, G,Pham, T,Fan, E,Madotto, F,Bajwa, EK,Brochard, L,Clarkson, K,Esteban, A,Gattinoni, L,van Haren, F,Heunks, LM,Kurahashi, K,Laake, JH,Larsson, A,McAuley, DF,McNamee, L,Nin, N,Qiu, HB,Ranieri, M,Rubenfeld, GD,Thompson, BT,Wrigge, H,Slutsky, AS,Pesenti, A,LUNG SAFE Investigators,ESICM Trials Grp (2016) 'Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study'. Intensive Care Medicine, 42 :1865-1876 [DOI] [Details]
(2016) 'Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts'
McDonnell, MJ,Aliberti, S,Goeminne, PC,Dimakou, K,Zucchetti, SC,Davidson, J,Ward, C,Laffey, JG,Finch, S,Pesci, A,Dupont, LJ,Fardon, TC,Skrbic, D,Obradovic, D,Cowman, S,Loebinger, MR,Rutherford, RM,De Soyza, A,Chalmers, JD (2016) 'Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts'. Thorax, 71 :1110-1118 [DOI] [Details]
(2016) 'Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries'
Bellani, G.,Laffey, J. G.,Pham, T.,Fan, E.,Brochard, L.,Esteban, A.,Gattinoni, L.,van Haren, F.,Larsson, A.,McAuley, D. F.,Ranieri, M.,Rubenfeld, G.,Thompson, B. T.,Wrigge, H.,Slutsky, A. S.,Pesenti, A. (2016) 'Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries'. JAMA, 315 (88):788-800 [Details]
(2016) 'Recent insights: mesenchymal stromal/stem cell therapy for acute respiratory distress syndrome'
Horie, S.,Laffey, J. G. (2016) 'Recent insights: mesenchymal stromal/stem cell therapy for acute respiratory distress syndrome'. F1000Res, 5 [Details]
(2016) 'Biotrauma and Ventilator-Induced Lung Injury: Clinical Implications'
Curley, G. F.,Laffey, J. G.,Zhang, H.,Slutsky, A. S. (2016) 'Biotrauma and Ventilator-Induced Lung Injury: Clinical Implications'. Chest, 150 (55):1109-1117 [Details]
(2016) 'Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-kappaB pathway'
Horie, S.,Ansari, B.,Masterson, C.,Devaney, J.,Scully, M.,O'Toole, D.,Laffey, J. G. (2016) 'Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-kappaB pathway'. Intensive Care Med Exp, 4 (11) [Details]
(2016) 'Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study'
McDonnell, MJ;Aliberti, S;Goeminne, PC;Restrepo, MI;Finch, S;Pesci, A;Dupont, LJ;Fardon, TC;Wilson, R;Loebinger, MR;Skrbic, D;Obradovic, D;De Soyza, A;Ward, C;Laffey, JG;Rutherford, RM;Chalmers, JD (2016) 'Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study'. Lancet Respiratory Medicine, 4 :969-979 [DOI] [Details]
(2016) 'What's new in cell therapies in ARDS?'
Horie, S.,Curley, G. F.,Laffey, J. G. (2016) 'What's new in cell therapies in ARDS?'. Intensive Care Med, 42 (55):779-82 [Details]
(2016) 'The ten studies that should be done in ARDS'
Bihari, S.,Laffey, J. G.,Bersten, A. D. (2016) 'The ten studies that should be done in ARDS'. Intensive Care Med, 42 (55):783-6 [Details]
(2015) 'Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat'
Hayes, M,Masterson, C,Devaney, J,Barry, F,Elliman, S,O'Brien, T,O'Toole, D,Curley, GF,Laffey, JG (2015) 'Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat'. Anesthesiology, 122 :363-373 [DOI] [Details]
(2015) 'Aerosol-Mediated Delivery of AAV2/6-I kappa B alpha Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats'
MacLoughlin, RJ,Higgins, BD,Devaney, J,O'Toole, D,Laffey, JG,O'Brien, T (2015) 'Aerosol-Mediated Delivery of AAV2/6-I kappa B alpha Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats'. Human Gene Therapy, 26 :36-46 [DOI] [Details]
(2015) 'Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat'
Devaney, J,Horie, S,Masterson, C,Elliman, S,Barry, F,O'Brien, T,Curley, GF,O'Toole, D,Laffey, JG (2015) 'Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat'. Thorax, 70 :625-635 [DOI] [Details]
(2015) 'Mechanical Stress and the Induction of Lung Fibrosis via the Midkine Signaling Pathway'
Zhang, R.,Pan, Y.,Fanelli, V.,Wu, S.,Luo, A. A.,Islam, D.,Han, B.,Mao, P.,Ghazarian, M.,Zeng, W.,Spieth, P. M.,Wang, D.,Khang, J.,Mo, H.,Liu, X.,Uhlig, S.,Liu, M.,Laffey, J.,Slutsky, A. S.,Li, Y.,Zhang, H. (2015) 'Mechanical Stress and the Induction of Lung Fibrosis via the Midkine Signaling Pathway'. Am J Respir Crit Care Med, 192 (33):315-23 [Details]
(2015) 'Noninvasive respiratory support for acute respiratory failure—high flow nasal cannula oxygen or non-invasive ventilation?'
Curley GF, Laffey JG, Zhang H, Slutsky AS (2015) 'Noninvasive respiratory support for acute respiratory failure—high flow nasal cannula oxygen or non-invasive ventilation?'. Journal Of Thoracic Disease, 7 (7):1092-7 [Details]
(2015) 'Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome'
Zambelli, V.,Bellani, G.,Borsa, R.,Pozzi, F.,Grassi, A.,Scanziani, M.,Castiglioni, V.,Masson, S.,Decio, A.,Laffey, J. G.,Latini, R.,Pesenti, A. (2015) 'Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome'. Intensive Care Med Exp, 3 (11) [Details]
(2015) 'Sepsis protects the myocardium and other organs from subsequent ischaemic/reperfusion injury via a MAPK-dependent mechanism'
Walshe, C. M.,Laffey, J. G.,Kevin, L.,O'Toole, D. (2015) 'Sepsis protects the myocardium and other organs from subsequent ischaemic/reperfusion injury via a MAPK-dependent mechanism'. Intensive Care Med Exp, 3 (11) [Details]
(2015) 'Tracheostomy procedures in the intensive care unit: an international survey'
Vargas, M.,Sutherasan, Y.,Antonelli, M.,Brunetti, I.,Corcione, A.,Laffey, J. G.,Putensen, C.,Servillo, G.,Pelosi, P. (2015) 'Tracheostomy procedures in the intensive care unit: an international survey'. Crit Care, 19 [Details]
(2015) 'Extracorporeal membrane oxygenation for blastomycosis-related severe ARDS: a new indication as a rescue therapy?'
Steinberg, B. E.,Goldenberg, N. M.,Laffey, J. G. (2015) 'Extracorporeal membrane oxygenation for blastomycosis-related severe ARDS: a new indication as a rescue therapy?'. Can J Anaesth, 62 (77):731-5 [Details]
(2015) 'Mesenchymal stromal cell therapies: potential and pitfalls for ARDS'
Masterson, C.,Jerkic, M.,Curley, G. F.,Laffey, J. G. (2015) 'Mesenchymal stromal cell therapies: potential and pitfalls for ARDS'. Minerva Anestesiol, 81 (22):179-94 [Details]
(2015) 'Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury'
Hayes, M.,Curley, G. F.,Masterson, C.,Devaney, J.,O'Toole, D.,Laffey, J. G. (2015) 'Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury'. Intensive Care Med Exp, 3 (11) [Details]
(2015) 'Future therapies for ARDS'
Curley, G. F.,Laffey, J. G. (2015) 'Future therapies for ARDS'. Intensive Care Med, 41 (22):322-6 [Details]
(2015) 'Permissive hypercapnia: what to remember'
Contreras, M.,Masterson, C.,Laffey, J. G. (2015) 'Permissive hypercapnia: what to remember'. Curr Opin Anaesthesiol, 28 (11):26-37 [Details]
(2014) 'Acidosis in the critically ill - balancing risks and benefits to optimize outcome'
Curley, G. F.,Laffey, J. G. (2014) 'Acidosis in the critically ill - balancing risks and benefits to optimize outcome'. Crit Care, 18 (22) [Details]
(2014) 'Simvastatin in the Acute Respiratory Distress Syndrome'
McAuley, DF;Laffey, JG;O'Kane, CM;Perkins, GD;Mullan, B;Trinder, TJ;Johnston, P;Hopkins, PA;Johnston, AJ;McDowell, C;McNally, C (2014) 'Simvastatin in the Acute Respiratory Distress Syndrome'. New England Journal of Medicine, 371 :1695-1703 [DOI] [Details]
(2014) 'Mesenchymal stem cell trials for pulmonary diseases'
Antunes, M. A.,Laffey, J. G.,Pelosi, P.,Rocco, P. R. (2014) 'Mesenchymal stem cell trials for pulmonary diseases'. J Cell Biochem, 115 (66):1023-32 [Details]
(2014) 'Mechanical ventilation-associated lung fibrosis in acute respiratory distress syndrome: a significant contributor to poor outcome'
Cabrera-Benitez, N. E.,Laffey, J. G.,Parotto, M.,Spieth, P. M.,Villar, J.,Zhang, H.,Slutsky, A. S. (2014) 'Mechanical ventilation-associated lung fibrosis in acute respiratory distress syndrome: a significant contributor to poor outcome'. Anesthesiology, 121 (11):189-98 [Details]
(2014) 'Pulmonary overexpression of inhibitor kappa B alpha decreases the severity of ventilator-induced lung injury in a rat model'
Hayes, M,Curley, GF,Masterson, C,Contreras, M,Ansari, B,Devaney, J,O'Toole, D,Laffey, JG (2014) 'Pulmonary overexpression of inhibitor kappa B alpha decreases the severity of ventilator-induced lung injury in a rat model'. British Journal Of Anaesthesia, 113 :1046-1054 [DOI] [Details]
(2014) 'The application of esophageal pressure measurement in patients with respiratory failure'
Akoumianaki, E.,Maggiore, S. M.,Valenza, F.,Bellani, G.,Jubran, A.,Loring, S. H.,Pelosi, P.,Talmor, D.,Grasso, S.,Chiumello, D.,Guerin, C.,Patroniti, N.,Ranieri, V. M.,Gattinoni, L.,Nava, S.,Terragni, P. P.,Pesenti, A.,Tobin, M.,Mancebo, J.,Brochard, L. (2014) 'The application of esophageal pressure measurement in patients with respiratory failure'. Am J Respir Crit Care Med, 189 (55):520-31 [Details]
(2014) 'Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation'
McAuley, D. F.,Curley, G. F.,Hamid, U. I.,Laffey, J. G.,Abbott, J.,McKenna, D. H.,Fang, X.,Matthay, M. A.,Lee, J. W. (2014) 'Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation'. Am J Physiol Lung Cell Mol Physiol, 306 (99) [Details]
(2014) 'Cell-based therapies for the acute respiratory distress syndrome'
Maron-Gutierrez, T.,Laffey, J. G.,Pelosi, P.,Rocco, P. R. (2014) 'Cell-based therapies for the acute respiratory distress syndrome'. Curr Opin Crit Care, 20 (11):122-31 [Details]
(2014) 'Therapeutic potential and mechanisms of action of mesenchymal stromal cells for Acute Respiratory Distress Syndrome'
Curley, G. F.,Scott, J. A.,Laffey, J. G. (2014) 'Therapeutic potential and mechanisms of action of mesenchymal stromal cells for Acute Respiratory Distress Syndrome'. Curr Stem Cell Res Ther, 9 (44):319-29 [Details]
(2013) 'Predicting the development of acute respiratory distress syndrome: searching for the Troponin of ARDS'
Laffey, J. G.,Talmor, D. (2013) 'Predicting the development of acute respiratory distress syndrome: searching for the Troponin of ARDS'. Am J Respir Crit Care Med, 187 (77):671-2 [Details]
(2013) 'CrossTalk proposal: there is added benefit to providing permissive hypercapnia in the treatment of ARDS'
Curley, G. F.,Laffey, J. G.,Kavanagh, B. P. (2013) 'CrossTalk proposal: there is added benefit to providing permissive hypercapnia in the treatment of ARDS'. J Physiol, 591 (1111):2763-5 [Details]
(2013) 'Cell therapy demonstrates promise for acute respiratory distress syndrome - but which cell is best?'
Curley, G. F.,Laffey, J. G. (2013) 'Cell therapy demonstrates promise for acute respiratory distress syndrome - but which cell is best?'. Stem Cell Res Ther, 4 (22) [Details]
(2013) 'Duration of analgesic effectiveness after the posterior and lateral transversus abdominis plane block techniques for transverse lower abdominal incisions: a meta-analysis'
Abdallah, F. W.,Laffey, J. G.,Halpern, S. H.,Brull, R. (2013) 'Duration of analgesic effectiveness after the posterior and lateral transversus abdominis plane block techniques for transverse lower abdominal incisions: a meta-analysis'. Br J Anaesth, 111 (55):721-35 [Details]
(2013) 'Inhibition of pulmonary nuclear factor kappa-B decreases the severity of acute Escherichia coli pneumonia but worsens prolonged pneumonia'
Devaney, J,Curley, GF,Hayes, M,Masterson, C,Ansari, B,O'Brien, T,O'Toole, D,Laffey, JG (2013) 'Inhibition of pulmonary nuclear factor kappa-B decreases the severity of acute Escherichia coli pneumonia but worsens prolonged pneumonia'. Critical care (London, England), 17 [DOI] [Details]
(2013) 'Comparison of the Baska (R) mask with the single-use laryngeal mask airway in low-risk female patients undergoing ambulatory surgery'
Alexiev, V,Ochana, A,Abdelrahman, D,Coyne, J,McDonnell, JG,O'Toole, DP,Neligan, P,Laffey, JG (2013) 'Comparison of the Baska (R) mask with the single-use laryngeal mask airway in low-risk female patients undergoing ambulatory surgery'. Anaesthesia, 68 :1026-1032 [DOI] [Details]
(2013) 'Effects of Intratracheal Mesenchymal Stromal Cell Therapy during Recovery and Resolution after Ventilator-induced Lung Injury'
Curley, GF,Ansari, B,Hayes, M,Devaney, J,Masterson, C,Ryan, A,Barry, F,O'Brien, T,O' Toole, D,Laffey, JG (2013) 'Effects of Intratracheal Mesenchymal Stromal Cell Therapy during Recovery and Resolution after Ventilator-induced Lung Injury'. Anesthesiology, 118 :924-933 [DOI] [Details]
(2012) 'Ischemia-reperfusion-induced lung injury: Could hypercapnia have a therapeutic role?*'
Ansari B, Laffey JG (2012) 'Ischemia-reperfusion-induced lung injury: Could hypercapnia have a therapeutic role?*'. Critical Care Medicine, 40 (2):688-690 [DOI] [Details]
(2012) 'Mesenchymal stem cells - a promising therapy for Acute Respiratory Distress Syndrome'
Hayes M, Curley G, Laffey JG (2012) 'Mesenchymal stem cells - a promising therapy for Acute Respiratory Distress Syndrome'. F1000 Medicine Reports, 4 [DOI] [Details]
(2012) 'Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat'
Curley, GF,Hayes, M,Ansari, B,Shaw, G,Ryan, A,Barry, F,O'Brien, T,O'Toole, D,Laffey, JG (2012) 'Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat'. Thorax, 67 :496-501 [DOI] [Details]
(2012) 'Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO2 Sensing and Signaling'
Oliver, KM,Lenihan, CR,Bruning, U,Cheong, A,Laffey, JG,McLoughlin, P,Taylor, CT,Cummins, EP (2012) 'Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO2 Sensing and Signaling'. Journal Of Biological Chemistry, 287 :14004-14011 [DOI] [Details]
(2012) 'An observational study of the Baska (R) mask: a novel supraglottic airway'
Alexiev, V,Salim, A,Kevin, LG,Laffey, JG (2012) 'An observational study of the Baska (R) mask: a novel supraglottic airway'. Anaesthesia, 67 :640-645 [DOI] [Details]
(2012) 'Studies on the pathogenesis and survival of different culture forms of Listeria monocytogenes to pulsed UV-light irradiation after exposure to mild-food processing stresses'
Bradley, D,McNeil, B,Laffey, JG,Rowan, NJ (2012) 'Studies on the pathogenesis and survival of different culture forms of Listeria monocytogenes to pulsed UV-light irradiation after exposure to mild-food processing stresses'. Food Microbiology, 30 :330-339 [DOI] [Details]
(2012) 'Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype?'
Hayes M, Curley G, Ansari B, Laffey JG (2012) 'Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype?'. Critical care (London, England), 16 (2) [DOI] [Details]
(2012) 'Hypercapnic acidosis attenuates ventilation-induced lung injury by a nuclear factor-kappa B dependent mechanism'
Contreras, M,Ansari, B,Curley, G,Higgins, BD,Hassett, P,O'Toole, D,Laffey, JG (2012) 'Hypercapnic acidosis attenuates ventilation-induced lung injury by a nuclear factor-kappa B dependent mechanism'. Critical Care Medicine, 40 :2622-2630 [DOI] [Details]
(2012) 'Relationship between growth of food-spoilage yeast in high-sugar environments and sensitivity to high-intensity pulsed UV light irradiation'
Hayes, JC,Laffey, JG,McNeil, B,Rowan, NJ (2012) 'Relationship between growth of food-spoilage yeast in high-sugar environments and sensitivity to high-intensity pulsed UV light irradiation'. International Journal Of Food Science And Technology, 47 :1925-1934 [DOI] [Details]
(2012) 'Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial'
McAuley, DF,Laffey, JG,O'Kane, CM,Cross, M,Perkins, GD,Murphy, L,McNally, C,Crealey, G,Stevenson, M (2012) 'Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial'. Trials, 13 [DOI] [Details]
(2011) 'Hypocapnia and the injured brain: Evidence for harm'
Curley G, Kavanagh BP, Laffey JG (2011) 'Hypocapnia and the injured brain: Evidence for harm'. Critical Care Medicine, 39 (1):229-230 [DOI] [Details]
(2011) 'Can ‘permissive’ hypercapnia modulate sepsis induced ALI/ARDS'
Curley G, Hayes M, Laffey JG. (2011) 'Can ‘permissive’ hypercapnia modulate sepsis induced ALI/ARDS'. Critical Care, 15 (2) [Details]
(2011) 'A comparison of three novel cuffed emergency percutaneous cricothyroidotomy devices to conventional surgical cricothyroidotomy in experienced Anaesthetists'
Murphy, C, Rooney, SJ, Maharaj CH, Laffey JG, Harte BH. (2011) 'A comparison of three novel cuffed emergency percutaneous cricothyroidotomy devices to conventional surgical cricothyroidotomy in experienced Anaesthetists'. British Journal Of Anaesthesia, 106 (1):57-64 [Details]
(2011) 'Gene based therapies for ALI/ARDS: where are we now?'
Devaney J, Contreras M, Laffey JG. (2011) 'Gene based therapies for ALI/ARDS: where are we now?'. Critical Care, 15 (3) [Details]
(2011) 'Casual bystander or active participant? New clues about adiponectin and traumatic injury'
White MB, Laffey JG, Kevin LG (2011) 'Casual bystander or active participant? New clues about adiponectin and traumatic injury'. Critical Care Medicine, 39 (8):2007-2008 [Details]
(2011) 'Strengthening the evidence base for airway equipment: time to become more ‘ADEPT’?'
Laffey, JG (2011) 'Strengthening the evidence base for airway equipment: time to become more ‘ADEPT’?'. Anaesthesia, 66 (8):656-658 [Details]
(2011) 'Special Populations – Critical illness and pregnancy'
Neligan P, Laffey JG (2011) 'Special Populations – Critical illness and pregnancy'. Critical Care, 15 [DOI] [Details]
(2011) 'Comparison of three cuffed emergency percutaneous cricothyroidotomy devices to conventional surgical cricothyroidotomy in a porcine model'
Murphy, C,Rooney, SJ,Maharaj, CH,Laffey, JG,Harte, BH (2011) 'Comparison of three cuffed emergency percutaneous cricothyroidotomy devices to conventional surgical cricothyroidotomy in a porcine model'. British Journal Of Anaesthesia, 106 :57-64 [DOI] [Details]
(2011) 'Comparison of the C-MAC (R), Airtraq (R), and Macintosh laryngoscopes in patients undergoing tracheal intubation with cervical spine immobilization'
McElwain, J,Laffey, JG (2011) 'Comparison of the C-MAC (R), Airtraq (R), and Macintosh laryngoscopes in patients undergoing tracheal intubation with cervical spine immobilization'. British Journal Of Anaesthesia, 107 :258-264 [DOI] [Details]
(2011) 'Stellate ganglion blockade for analgesia following upper limb surgery'
McDonnell, JG,Finnerty, O,Laffey, JG (2011) 'Stellate ganglion blockade for analgesia following upper limb surgery'. Anaesthesia, 66 :611-614 [DOI] [Details]
(2011) 'Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat'
Curley, GF,Contreras, M,Higgins, B,O'Kane, C,McAuley, DF,O'Toole, D,Laffey, JG (2011) 'Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat'. Anesthesiology, 115 :1022-1032 [DOI] [Details]
(2011) 'A rude awakening after our fourth ‘NAP’: lessons for Airway Management'
O'Sullivan E, Laffey J, Pandit JJ. (2011) 'A rude awakening after our fourth ‘NAP’: lessons for Airway Management'. Anaesthesia, 66 (5):390-392 [DOI] [Details]
(2011) 'A Comparison of the C-MAC®, Airtraq®, and Macintosh Laryngoscopes in Patients undergoing tracheal intubation with Cervical Spine Immobilisation'
McElwain J, Laffey JG (2011) 'A Comparison of the C-MAC®, Airtraq®, and Macintosh Laryngoscopes in Patients undergoing tracheal intubation with Cervical Spine Immobilisation'. British Journal Of Anaesthesia, 107 (2):258-264 [Details]
(2011) 'Clinical review: Special populations--critical illness and pregnancy'
Neligan PJ, Laffey JG (2011) 'Clinical review: Special populations--critical illness and pregnancy'. Critical care (London, England), 15 (4) [DOI] [Details]
(2011) 'Hypocapnia induced cerebral ischaemia during therapeutic hypothermia-Potential for harm?'
Curley G, Laffey JG (2011) 'Hypocapnia induced cerebral ischaemia during therapeutic hypothermia-Potential for harm?'. Resuscitation, 82 (9):1122-1123 [DOI] [Details]
(2011) 'Clinical review: gene-based therapies for ALI/ARDS: where are we now?'
Devaney J, Contreras M, Laffey JG (2011) 'Clinical review: gene-based therapies for ALI/ARDS: where are we now?'. Critical care (London, England), 15 (3) [DOI] [Details]
(2011) 'Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS?'
Curley G, Hayes M, Laffey JG (2011) 'Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS?'. Critical care (London, England), 15 (2) [DOI] [Details]
(2011) 'Selective Gut Decontamination: The authors reply'
Quigley, E.M., Laffey, J.G. (2011) 'Selective Gut Decontamination: The authors reply'. Critical Care Medicine, 39 (12) [Details]
(2011) 'Overexpression of pulmonary extracellular uperoxide dismutase attenuates endotoxin induced acute lung injury'
Hassett P, Curley GF, Contreras M, Masterson C, Higgins BD, O'Brien T, Devaney J, O'Toole D, Laffey JG. (2011) 'Overexpression of pulmonary extracellular uperoxide dismutase attenuates endotoxin induced acute lung injury'. Intensive Care Medicine, 37 (10):1680-1687 [Details]
(2011) 'Studies on the relationship between pulsed UV light irradiation and the simultaneous occurrence of molecular and cellular damage in clinically-relevant Candida albicans'
Farrell, H,Hayes, J,Laffey, J,Rowan, N (2011) 'Studies on the relationship between pulsed UV light irradiation and the simultaneous occurrence of molecular and cellular damage in clinically-relevant Candida albicans'. Journal Of Microbiological Methods, 84 :317-326 [DOI] [Details]
(2011) 'Placebo blocks in local anaesthesia studies: the need for balance'
Laffey J (2011) 'Placebo blocks in local anaesthesia studies: the need for balance'. Anaesthesia, 66 (5):390-31 [DOI] [Details]
(2011) 'Studies on the spread of local anaesthetic solution in transversus abdominis plane blocks'
Carney, J,Finnerty, O,Rauf, J,Bergin, D,Laffey, JG,Mc Donnell, JG (2011) 'Studies on the spread of local anaesthetic solution in transversus abdominis plane blocks'. Anaesthesia, 66 :1023-1030 [DOI] [Details]
(2011) 'Lung stem cells - from an evolving understanding to a paradigm shift?'
Hayes, M,Curley, GF,Laffey, JG (2011) 'Lung stem cells - from an evolving understanding to a paradigm shift?'. Stem Cell Research & Therapy, 2 [DOI] [Details]
(2010) 'Comparison of the C-MAC Videolaryngoscope with the Glidescope, Airtraq and Macintosh laryngoscope in easy and difficult laryngoscopy scenarios in manikins'
McElwain, J., Malik, M.A.,Harte, B.H., Flynn, N.M.,Laffey, J.G. (2010) 'Comparison of the C-MAC Videolaryngoscope with the Glidescope, Airtraq and Macintosh laryngoscope in easy and difficult laryngoscopy scenarios in manikins'. Anaesthesia, [DOI] [Details]
(2010) 'Investigation of critical inter-related factors affecting the efficacy of pulsed light for inactivating clinically relevant bacterial pathogens'
Farrell, HP,Garvey, M,Cormican, M,Laffey, JG,Rowan, NJ (2010) 'Investigation of critical inter-related factors affecting the efficacy of pulsed light for inactivating clinically relevant bacterial pathogens'. Journal Of Applied Microbiology, 108 :1494-1508 [DOI] [Details]
(2010) 'Determination of the optimal stylet strategy for the C-MAC (R) videolaryngoscope'
McElwain, J,Malik, MA,Harte, BH,Flynn, NH,Laffey, JG (2010) 'Determination of the optimal stylet strategy for the C-MAC (R) videolaryngoscope'. Anaesthesia, 65 :369-378 [DOI] [Details]
(2010) 'Ipsilateral Transversus Abdominis Plane Block Provides Effective Analgesia After Appendectomy in Children: A Randomized Controlled Trial'
Carney, J,Finnerty, O,Rauf, J,Curley, G,McDonnell, JG,Laffey, JG (2010) 'Ipsilateral Transversus Abdominis Plane Block Provides Effective Analgesia After Appendectomy in Children: A Randomized Controlled Trial'. Anesthesia And Analgesia, 111 :998-1003 [DOI] [Details]
(2010) 'Letter regarding IDS score'
McElwain J, Malik MA, Laffey JG. (2010) 'Letter regarding IDS score'. Br J Anaes 2010 (in press), [Details]
(2010) 'Hypocapnia and the injured brain: more harm than benefit'
Curley G, Kavanagh BP, Laffey JG (2010) 'Hypocapnia and the injured brain: more harm than benefit'. Critical Care Medicine, 38 (5):1348-1359 [DOI] [Details]
(2010) 'Determination of the optimal stylet strategy for use with the C-MAC laryngoscope – A manikin study'
McElwain J, Malik MA, Harte BH, Flynn NH, Laffey JG, (2010) 'Determination of the optimal stylet strategy for use with the C-MAC laryngoscope – A manikin study'. Anaesthesia, 65 (4):369-378 [DOI] [Details]
(2010) 'Bench to Bedside Review: Carbon Dioxide'
Curley G, Laffey JG, Kavanagh BP. (2010) 'Bench to Bedside Review: Carbon Dioxide'. Critical Care, 14 (220) [Details]
(2010) 'Hypercapnia and acidosis in sepsis: a double-edged sword?'
Curley G, Contreras MM, Nichol AD, Higgins BD, Laffey JG (2010) 'Hypercapnia and acidosis in sepsis: a double-edged sword?'. Anesthesiology, 112 (2):462-472 [DOI] [Details]
(2010) 'Comparison of the C-MAC (R) videolaryngoscope with the Macintosh, Glidescope (R), and Airtraq (R) laryngoscopes in easy and difficult laryngoscopy scenarios in manikins'
McElwain, J,Malik, MA,Harte, BH,Flynn, NM,Laffey, JG (2010) 'Comparison of the C-MAC (R) videolaryngoscope with the Macintosh, Glidescope (R), and Airtraq (R) laryngoscopes in easy and difficult laryngoscopy scenarios in manikins'. Anaesthesia, 65 :483-489 [DOI] [Details]
(2009) 'Comparison of the Airtraq and Truview laryngoscopes to the Macintosh laryngoscope for use by Advanced Paramedics in easy and simulated difficult intubation in manikins'
Nasim S, Maharaj CH, Butt I, Malik MA, O' Donnell J, Higgins BD, Harte BH, Laffey JG (2009) 'Comparison of the Airtraq and Truview laryngoscopes to the Macintosh laryngoscope for use by Advanced Paramedics in easy and simulated difficult intubation in manikins'. BMC Emerg Med, 9 [DOI] [Details]
(2009) 'Tracheal intubation in patients with cervical spine immobilization: A comparison of the Airwayscope, LMA CTrach, and the Macintosh laryngoscopes. '
Murphy C, Rooney SJ, Maharaj CH, Laffey JG, Harte BH.  (2009) 'Tracheal intubation in patients with cervical spine immobilization: A comparison of the Airwayscope, LMA CTrach, and the Macintosh laryngoscopes. '. Br J Anaesth, 102 (5):654-661 [DOI] [Details]
(2009) 'Mechanical ventilation: taking its toll on the lung'
Curley GF, Kevin LG, Laffey JG (2009) 'Mechanical ventilation: taking its toll on the lung'. Anesthesiology, 111 (4):701-703 [DOI] [Details]
(2009) 'A comparison of the Glidescope, Pentax AWS, and Macintosh laryngoscopes when used by novice personnel: a manikin study'
Malik MA, Hassett P, Carney J, Higgins BD, Harte BH, Laffey JG (2009) 'A comparison of the Glidescope, Pentax AWS, and Macintosh laryngoscopes when used by novice personnel: a manikin study'. Canadian Journal Of Anaesthesia-Journal Canadien D Anesthesie, 56 (11):802-811 [DOI] [Details]
(2009) 'Lung Injury and is Impact in ACS'
Laffey, J. G. (2009) 'Lung Injury and is Impact in ACS'. Acta Clinica Belgica, 64 (33):248-248 [Details]
(2009) 'Randomized controlled trial of the Pentax AWS (R), Glidescope (R), and Macintosh laryngoscopes in predicted difficult intubation'
Malik, MA,Subramaniam, R,Maharaj, CH,Harte, BH,Laffey, JG (2009) 'Randomized controlled trial of the Pentax AWS (R), Glidescope (R), and Macintosh laryngoscopes in predicted difficult intubation'. British Journal Of Anaesthesia, 103 :761-768 [DOI] [Details]
(2009) 'Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappa B dependent mechanism'
O'Toole, D,Hassett, P,Contreras, M,Higgins, BD,McKeown, STW,McAuley, DF,O'Brien, T,Laffey, JG (2009) 'Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappa B dependent mechanism'. Thorax, 64 :976-982 [DOI] [Details]
(2009) 'Effects and mechanisms of action of sildenafil citrate in human chorionic arteries'
Maharaj, CH,O'Toole, D,Lynch, T,Carney, J,Jarman, J,Higgins, BD,Morrison, JJ,Laffey, JG (2009) 'Effects and mechanisms of action of sildenafil citrate in human chorionic arteries'. Reproductive Biology And Endocrinology, 7 [DOI] [Details]
(2009) 'Comparison of the Glidescope (R), the Pentax AWS (R), and the Truview EVO2 (R) with the Macintosh laryngoscope in experienced anaesthetists: a manikin study'
Malik, MA,O'Donoghue, C,Carney, J,Maharaj, CH,Harte, BH,Laffey, JG (2009) 'Comparison of the Glidescope (R), the Pentax AWS (R), and the Truview EVO2 (R) with the Macintosh laryngoscope in experienced anaesthetists: a manikin study'. British Journal Of Anaesthesia, 102 :128-134 [DOI] [Details]
(2009) 'A comparison of the Glidescope (R), Pentax AWS (R), and Macintosh laryngoscopes when used by novice personnel: a manikin study'
Malik, MA,Hassett, P,Carney, J,Higgins, BD,Harte, BH,Laffey, JG (2009) 'A comparison of the Glidescope (R), Pentax AWS (R), and Macintosh laryngoscopes when used by novice personnel: a manikin study'. Canadian Journal Of Anaesthesia-Journal Canadien D Anesthesie, 56 :802-811 [DOI] [Details]
(2009) 'Differential Effects of Buffered Hypercapnia versus Hypercapnic Acidosis on Shock and Lung Injury Induced by Systemic Sepsis'
Higgins, BD,Costello, J,Contreras, M,Hassett, P,O'Toole, D,Laffey, JG (2009) 'Differential Effects of Buffered Hypercapnia versus Hypercapnic Acidosis on Shock and Lung Injury Induced by Systemic Sepsis'. Anesthesiology, 111 :1317-1326 [Details]
(2009) 'A comparison of the Glidescope ®, the Pentax AWS ® and the Truview ® EVO2 to the Macintosh laryngoscope in experienced Anaesthetists – A manikin study'
Carney J, Finnerty O, Rauf J, Curley G, McDonnell JG, Laffey JG.  (2009) 'A comparison of the Glidescope ®, the Pentax AWS ® and the Truview ® EVO2 to the Macintosh laryngoscope in experienced Anaesthetists – A manikin study'. Br J Anaes, 102 :128-134 [DOI] [Details]
(2009) 'Role of potassium and calcium channels in sevoflurane-mediated vasodilation in the foeto-placental circulation'
Jarman J, Maharaj CH, Higgins BD, Farragher RF, Laffey CD, Flynn NM, Laffey JG (2009) 'Role of potassium and calcium channels in sevoflurane-mediated vasodilation in the foeto-placental circulation'. BMC Anesthesiol, 9 [DOI] [Details]
(2008) 'Determination of the efficacy and side-effect profile of lower doses of Intrathecal Morphine in Patients undergoing Total Knee Replacement'
Higgins BD, Costello J, Contreras M, Hassett P, O' Toole D, Laffey JG.  (2008) 'Determination of the efficacy and side-effect profile of lower doses of Intrathecal Morphine in Patients undergoing Total Knee Replacement'. BMC Anesthesiology, 8 (5) [Details]
(2008) 'Determination Of The Efficacy And Side-effect Profile Of Lower Doses Of Intrathecal Morphine In Patients Undergoing Total Knee Arthroplasty'
Hassett P, Ansari B, Gnanamoorthy P, Kinirons B, Laffey JG (2008) 'Determination Of The Efficacy And Side-effect Profile Of Lower Doses Of Intrathecal Morphine In Patients Undergoing Total Knee Arthroplasty'. BMC Anesthesiol, 8 [DOI] [Details]
(2008) 'Carbon monoxide: from poison to therapy for cardiopulmonary bypass-induced lung injury?'
Kevin LG, Laffey JG (2008) 'Carbon monoxide: from poison to therapy for cardiopulmonary bypass-induced lung injury?'. Anesthesiology, 108 (6):977-978 [DOI] [Details]
(2008) 'Evaluation of the Airtraq and Macintosh laryngoscopes in patients at increased risk for difficult tracheal intubation'
Maharaj CH, Costello JF, Harte BH, Laffey JG (2008) 'Evaluation of the Airtraq and Macintosh laryngoscopes in patients at increased risk for difficult tracheal intubation'. Anaesthesia, 63 (2):182-188 [DOI] [Details]
(2008) 'Sevoflurane and the feto-placental vasculature: The role of nitric oxide and vasoactive eicosanoids'
Farragher, R,Maharaj, CH,Higgins, BD,Crowe, S,Burke, P,Laffey, CD,Flynn, NM,Laffey, JG (2008) 'Sevoflurane and the feto-placental vasculature: The role of nitric oxide and vasoactive eicosanoids'. Anesthesia And Analgesia, 107 :171-177 [DOI] [Details]
(2008) 'Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury'
O'Croinin, DF,Nichol, AD,Hopkins, N,Boylan, J,O'Brien, S,O'Connor, C,Laffey, JG,McLoughlin, P (2008) 'Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury'. Critical Care Medicine, 36 :2128-2135 [DOI] [Details]
(2008) 'A Comparison of Macintosh, Truview EV02â, Glidescope® and Airwayscope® Laryngoscopes in Patients with Cervical Spine Immobilization'
Higgins BD, Costello J, Contreras M, Hassett P, O' Toole D, Laffey JG.  (2008) 'A Comparison of Macintosh, Truview EV02â, Glidescope® and Airwayscope® Laryngoscopes in Patients with Cervical Spine Immobilization'. Br J Anaesth, 101 (5):723-730 [DOI] [Details]
(2008) 'Comparison of Macintosh, Truview EVO2 (R), Glidescope (R), and Airwayscope (R) laryngoscope use in patients with cervical spine immobilization'
Malik, MA,Maharaj, CH,Harte, BH,Laffey, JG (2008) 'Comparison of Macintosh, Truview EVO2 (R), Glidescope (R), and Airwayscope (R) laryngoscope use in patients with cervical spine immobilization'. British Journal Of Anaesthesia, 101 :723-730 [DOI] [Details]
(2008) 'The analgesic efficacy of transversus abdominis plane block after cesarean delivery: A randomized controlled trial'
McDonnell, JG,Curley, G,Carney, J,Benton, A,Costello, J,Maharaj, CH,Laffey, JG (2008) 'The analgesic efficacy of transversus abdominis plane block after cesarean delivery: A randomized controlled trial'. Anesthesia And Analgesia, 106 :186-191 [DOI] [Details]
(2008) 'Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury'
Kennedy MT, Higgins BD, Costello JF, Curtin WA, Laffey JG (2008) 'Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury'. BMC pulmonary medicine, 8 [DOI] [Details]
(2008) 'Hypercapnic acidosis attenuates the severity of severe pulmonary sepsis by a neutrophil independent mechanism'
Malik MA, Maharaj CH, Harte BH, Laffey JG. (2008) 'Hypercapnic acidosis attenuates the severity of severe pulmonary sepsis by a neutrophil independent mechanism'. Critical Care Medicine, 36 (12):3135-3144 [DOI] [Details]
(2008) 'Hypercapnic acidosis attenuates lung injury induced by established bacterial pneumonia'
Chonghaile MN, Higgins BD, Costello J, Laffey JG (2008) 'Hypercapnic acidosis attenuates lung injury induced by established bacterial pneumonia'. Anesthesiology, 109 (5):837-848 [DOI] [Details]
(2008) 'Hypercapnic acidosis attenuates severe acute bacterial pneumonia-induced lung injury by a neutrophil-independent mechanism'
Chonghaile, MN,Higgins, BD,Costello, JF,Laffey, JG (2008) 'Hypercapnic acidosis attenuates severe acute bacterial pneumonia-induced lung injury by a neutrophil-independent mechanism'. Critical Care Medicine, 36 :3135-3144 [DOI] [Details]
(2007) 'Meralgia Paraesthetica [Letter] (in press)'
Lynch T, Kinirons B, Laffey JG (2007) 'Meralgia Paraesthetica [Letter] (in press)'. IRISH MEDICAL JOURNAL, [Details]
(2007) 'Transversus abdominis plane block'
McDonnell JG, Laffey JG (2007) 'Transversus abdominis plane block'. Anesthesia And Analgesia, 105 (3) [DOI] [Details]
(2007) 'Permissive hypercapnia: Balancing risks and benefits in the peripheral microcirculation'
Hassett P, Laffey JG (2007) 'Permissive hypercapnia: Balancing risks and benefits in the peripheral microcirculation'. Critical Care Medicine, 35 (9):2229-2231 [DOI] [Details]
(2007) 'Implementing scientific advances into clinical practice in critical care--new challenges and new insights'
Costello JF, Laffey JG (2007) 'Implementing scientific advances into clinical practice in critical care--new challenges and new insights'. Critical Care Medicine, 35 (7):1779-1780 [DOI] [Details]
(2007) 'Transversus abdominis plane block: A cadaveric and radiological evaluation'
McDonnell, JG,O'Donnell, BD,Farrell, T,Gough, N,Tuite, D,Power, C,Laffey, JG (2007) 'Transversus abdominis plane block: A cadaveric and radiological evaluation'. Regional Anesthesia And Pain Medicine, 32 :399-404 [DOI] [Details]
(2007) 'Recovery of older patients undergoing ambulatory anaesthesia with isoflurane or sevoflurane'
Mahajan, VA,Ni Chonghaile, M,Bokhari, SA,Harte, BH,Flynn, NM,Laffey, JG (2007) 'Recovery of older patients undergoing ambulatory anaesthesia with isoflurane or sevoflurane'. European Journal Of Anaesthesiology, 24 :505-510 [DOI] [Details]
(2007) 'Endotracheal intubation in patients with cervical spine immobilization - A comparison of Macintosh and Airtraq laryngoscopes'
Maharaj, CH,Buckley, E,Harte, BH,Laffey, JG (2007) 'Endotracheal intubation in patients with cervical spine immobilization - A comparison of Macintosh and Airtraq laryngoscopes'. Anesthesiology, 107 :53-59 [Details]
(2007) 'The Airtraq (R) as a rescue airway device following failed direct laryngoscopy: a case series'
Maharaj, CH,Costello, JF,McDonnell, JG,Harte, BH,Laffey, JG (2007) 'The Airtraq (R) as a rescue airway device following failed direct laryngoscopy: a case series'. Anaesthesia, 62 :598-601 [DOI] [Details]
(2007) 'Retention of tracheal intubation skills by novice personnel: a comparison of the Airtraq (R) and Macintosh laryngoscopes'
Maharaj, CH,Costello, J,Higgins, BD,Harte, BH,Laffey, JG (2007) 'Retention of tracheal intubation skills by novice personnel: a comparison of the Airtraq (R) and Macintosh laryngoscopes'. Anaesthesia, 62 :272-278 [DOI] [Details]
(2007) 'A comparison of direct and indirect laryngoscopes and the ILMA in novice users: a manikin study'
Maharaj, CH,McDonnell, JG,Harte, BH,Laffey, JG (2007) 'A comparison of direct and indirect laryngoscopes and the ILMA in novice users: a manikin study'. Anaesthesia, 62 :1161-1166 [DOI] [Details]
(2006) 'Evaluation of ease of intubation with the Airtraq® or Macintosh laryngoscope in routine airway management: a randomized, controlled clinical trial'
Maharaj CH, O' Croinin D, Curley G, Harte BH, Laffey JG (2006) 'Evaluation of ease of intubation with the Airtraq® or Macintosh laryngoscope in routine airway management: a randomized, controlled clinical trial'. [Details]
(2006) 'Hypercapnia: permissive and therapeutic'
Kavanagh BP, Laffey JG (2006) 'Hypercapnia: permissive and therapeutic'. Minerva anestesiologica, 72 (6):567-576 [Details]
(2006) 'Sildenafil for pulmonary hypertension in pregnancy?'
Lynch TD, Laffey JG (2006) 'Sildenafil for pulmonary hypertension in pregnancy?'. Anesthesiology, 104 (2) [Details]
(2006) 'Tracheal intubation by inexperienced medical residents using the Airtraq and Macintosh laryngoscopes - a manikin study'
Maharaj, CH,Chonghaile, MN,Higgins, BD,Harte, BH,Laffey, JG (2006) 'Tracheal intubation by inexperienced medical residents using the Airtraq and Macintosh laryngoscopes - a manikin study'. American Journal Of Emergency Medicine, 24 :769-774 [DOI] [Details]
(2006) 'Evaluation of intubation using the Airtraq (R) or Macintosh laryngoscope by anaesthetists in easy and simulated difficult laryngoscopy - a manikin study'
Maharaj, CH,Higgins, BD,Harte, BH,Laffey, JG (2006) 'Evaluation of intubation using the Airtraq (R) or Macintosh laryngoscope by anaesthetists in easy and simulated difficult laryngoscopy - a manikin study'. Anaesthesia, 61 :469-477 [DOI] [Details]
(2006) 'A comparison of tracheal intubation using the Airtraq (R) or the Macintosh laryngoscope in routine airway management: a randomised, controlled clinical trial'
Maharaj, CH,O'Croinin, D,Curley, G,Harte, BH,Laffey, JG (2006) 'A comparison of tracheal intubation using the Airtraq (R) or the Macintosh laryngoscope in routine airway management: a randomised, controlled clinical trial'. Anaesthesia, 61 :1093-1099 [DOI] [Details]
(2006) 'Learning and performance of tracheal intubation by novice personnel: a comparison of the Airtraq (R) and Macintosh laryngoscope'
Maharaj, CH,Costello, JF,Higgins, BD,Harte, BH,Laffey, JG (2006) 'Learning and performance of tracheal intubation by novice personnel: a comparison of the Airtraq (R) and Macintosh laryngoscope'. Anaesthesia, 61 :671-677 [DOI] [Details]
(2006) 'Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection'
Hopkins, N,Gunning, Y,O'Croinin, DF,Laffey, J,McLoughlin, P (2006) 'Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection'. Journal Of Pathology, 209 :198-205 [DOI] [Details]
(2005) 'Maternal Brain Death'
Farragher R, Laffey JG (2005) 'Maternal Brain Death'. Neurocritical Care, [Details]
(2005) 'Maternal brain death and somatic support'
Farragher RA, Laffey JG (2005) 'Maternal brain death and somatic support'. Critical care (London, England), 3 (2):99-106 [DOI] [Details]
(2005) 'Preoperative intravenous fluid therapy decreases postoperative nausea and pain in high risk patients'
Maharaj CH, Kallam SR, Malik A, Hassett P, Grady D, Laffey JG (2005) 'Preoperative intravenous fluid therapy decreases postoperative nausea and pain in high risk patients'. Anesthesia And Analgesia, 100 (3):675-61 [DOI] [Details]
(2005) 'Bench-to-bedside review: Permissive hypercapnia'
O'Croinin D, Ni Chonghaile M, Higgins B, Laffey JG (2005) 'Bench-to-bedside review: Permissive hypercapnia'. Critical care (London, England), 9 (1):51-59 [DOI] [Details]
(2005) 'Hypercapnic acidosis does not modulate the severity of bacterial pneumonia-induced lung injury'
O'Croinin, DF,Hopkins, NO,Moore, MM,Boylan, JF,McLoughlin, P,Laffey, JG (2005) 'Hypercapnic acidosis does not modulate the severity of bacterial pneumonia-induced lung injury'. Critical Care Medicine, 33 :2606-2612 [DOI] [Details]
(2005) 'Maternal Brain Death – an Irish Perspective'
Farragher R, Marsh B, Laffey JG (2005) 'Maternal Brain Death – an Irish Perspective'. IRISH JOURNAL OF MEDICAL SCIENCE, [Details]
(2005) 'Permissive hypercapnia: role in protective lung ventilatory strategies'
Ni Chonghaile M, Higgins B, Laffey JG (2005) 'Permissive hypercapnia: role in protective lung ventilatory strategies'. Critical care (London, England), 11 (1):56-62 [Details]
(2004) 'Permissive Hypercapnia – Role in Protective Lung Ventilatory Strategies'
Croinin D, McLoughlin P, Kavanagh BP, Laffey JG (2004) 'Permissive Hypercapnia – Role in Protective Lung Ventilatory Strategies'. Intensive Care Medicine, [Details]
(2004) 'Hypercapnic acidosis attenuates endotoxin-induced acute lung injury'
Laffey JG, Honan D, Hopkins N, Hyvelin JM, Boylan JF, McLoughlin P (2004) 'Hypercapnic acidosis attenuates endotoxin-induced acute lung injury'. Critical Care Medicine, 169 (1):46-56 [DOI] [Details]
(2004) 'New strategies to control the inflammatory response in cardiac surgery'
Maharaj C, Laffey JG (2004) 'New strategies to control the inflammatory response in cardiac surgery'. Current opinion in anaesthesiology, 17 (1):35-48 [Details]
(2004) 'Strategies that attenuate the Inflammatory response to Cardiac Surgery. Current Opinion in Anaesthesiology'
Maharaj C, Laffey JG (2004) 'Strategies that attenuate the Inflammatory response to Cardiac Surgery. Current Opinion in Anaesthesiology'. Current Opinion in Anaesthesiology, [Details]
(2004) 'Maternal brain death: medical, ethical and legal issues'
Lane, A,Westbrook, A,Grady, D,O'Connor, R,Counihan, TJ,Marsh, B,Laffey, JG (2004) 'Maternal brain death: medical, ethical and legal issues'. Intensive Care Medicine, 30 :1484-1486 [DOI] [Details]
(2004) 'Therapeutic Hypercapnia Improves Oxygenation but does not Protect Against Stretch-Induced Injury in the in vivo Saline-Lavaged Rabbit'
S Rai, Engelberts D, Laffey JG, Frevert C, Kajikawa O, Martin TR, Post M, Kavanagh BP (2004) 'Therapeutic Hypercapnia Improves Oxygenation but does not Protect Against Stretch-Induced Injury in the in vivo Saline-Lavaged Rabbit'. Pediatric Research, [Details]
(2004) 'Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung'
Rai S, Engelberts D, Laffey JG, Frevert C, Kajikawa O, Martin TR, Post M, Kavanagh BP (2004) 'Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung'. Pediatric research, 55 (1):42-49 [DOI] [Details]
(2003) 'Perioperative control of CO2'
BP Kavanagh, Laffey JG (2003) 'Perioperative control of CO2'. Canadian Journal of Anesthesia (Supplement), [Details]
(2003) 'Effects of Therapeutic Hypercapnia on Mesenteric Ischemia – Reperfusion Injury'
Jankov R, Engelberts D, Tanswell AK, Post M, Lindsay T, Mullen JB, Romaschin A, Stephens D, McKerlie C, Kavanagh BP, Laffey JG (2003) 'Effects of Therapeutic Hypercapnia on Mesenteric Ischemia – Reperfusion Injury'. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDIC, [Details]
(2003) 'A simple artificial neural network can help predict residual neuromuscular blockade'
Tobin E, Boylan J, McShane AJ, Laffey JG (2003) 'A simple artificial neural network can help predict residual neuromuscular blockade'. British Journal of Anaesthesia, :48-52 [Details]
(2003) 'Interleukin-1ß Rapidly inhibits Aortic Endothelium-Dependent relaxation by a DNA Transcription-Dependent mechanism'
Loughrey J, Laffey JG, Moore B, Lynch F, McLoughlin P, Boylan J (2003) 'Interleukin-1ß Rapidly inhibits Aortic Endothelium-Dependent relaxation by a DNA Transcription-Dependent mechanism'. Critical Care Medicine, :910-915 [Details]
(2003) 'Assessment of a simple artificial neural network for predicting residual neuromuscular block'
Laffey JG, Tobin E, Boylan JF, McShane AJ (2003) 'Assessment of a simple artificial neural network for predicting residual neuromuscular block'. Br J Anaesth, 90 (1):48-52 [Details]
(2003) 'Optimizing the dose of intrathecal morphine in older patients undergoing hip arthroplasty'
Murphy, PM,Stack, D,Kinirons, B,Laffey, JG (2003) 'Optimizing the dose of intrathecal morphine in older patients undergoing hip arthroplasty'. Anesthesia And Analgesia, 97 :1709-1715 [DOI] [Details]
(2003) 'Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation'
Laffey JG, Engelberts D, Duggan M, Veldhuizen R, Lewis JF, Kavanagh BP (2003) 'Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation'. Critical Care Medicine, 31 (11):2634-2640 [DOI] [Details]
(2002) 'Droperidol and Cyclizine have comparable antiemetic efficacy and side effects during patient controlled analgesia'
Boylan JF, Laffey JG (2002) 'Droperidol and Cyclizine have comparable antiemetic efficacy and side effects during patient controlled analgesia'. IRISH JOURNAL OF MEDICAL SCIENCE, :141-144 [Details]
(2002) 'The systemic inflammatory response to Cardiac Surgery – implications for the Anesthesiologist'
Boylan JF, Cheng, DCH, Laffey JG (2002) 'The systemic inflammatory response to Cardiac Surgery – implications for the Anesthesiologist'. Anesthesiology, :215-252 [Details]
(2002) 'Cyclizine and droperidol have comparable efficacy and side effects during patient-controlled analgesia'
Laffey JG, Boylan JF (2002) 'Cyclizine and droperidol have comparable efficacy and side effects during patient-controlled analgesia'. Ir J Med Sci, 171 (3):141-144 [Details]
(2002) 'An audit of activity patterns in a HDU and its impact on ICU utilization'
Curran E, O' Gorman D. Phelan D, Laffey JG (2002) 'An audit of activity patterns in a HDU and its impact on ICU utilization'. Clinical Intensive Care, :13-20 [Details]
(2002) 'Hypocapnia'
Laffey JG, Kavanagh BP (2002) 'Hypocapnia'. The New England journal of medicine, 347 (1):43-53 [DOI] [Details]
(2002) 'Acid-base disorders in the critically ill'
Laffey JG (2002) 'Acid-base disorders in the critically ill'. Anaesthesia, 57 (2) [Details]
(2002) 'Mechanisms of Disease: Hypocapnia'
Kavanagh BP, Laffey JG (2002) 'Mechanisms of Disease: Hypocapnia'. NEW ENGLISH JOURNAL OF MEDICINE, :43-53 [Details]
(2002) 'Isoprostanes--markers of ischaemia reperfusion injury'
Sakamoto H, Corcoran TB, Laffey JG, Shorten GD (2002) 'Isoprostanes--markers of ischaemia reperfusion injury'. European Journal Of Anaesthesiology, 19 (8):550-559 [Details]
(2001) 'Protective effects of acidosis'
Laffey JG (2001) 'Protective effects of acidosis'. Anaesthesia, 56 (10):1013-1014 [Details]
(2001) 'Patient compliance with pre-operative day case instructions'
Laffey JG, Boylan JF (2001) 'Patient compliance with pre-operative day case instructions'. Anaesthesia, 56 (9) [Details]
(2001) 'Low-dose spinal morphine for postoperative analgesia following knee arthroplasty'
Laffey JG, Flynn N (2001) 'Low-dose spinal morphine for postoperative analgesia following knee arthroplasty'. Br J Anaesth, 86 (1):152-153 [Details]
(2000) 'Postoperative neurological deficit despite normal cerebral oximetry during carotid endarterectomy'
Mehigan D, Boylan, Laffey JG (2000) 'Postoperative neurological deficit despite normal cerebral oximetry during carotid endarterectomy'. Journal of Clinical Anaesthesia, :573-574 [Details]
(2000) 'Effects of intracuff lidocaine on endotracheal-tube-induced emergence phenomena following general anaesthesia'
Fagan C, Frizelle HP, Laffey JG, Hannon V, Carey M (2000) 'Effects of intracuff lidocaine on endotracheal-tube-induced emergence phenomena following general anaesthesia'. Anaesthesia and Analgesia, :201-205 [Details]
(2000) 'Buffering hypercapnic acidosis worsens acute lung injury'
Laffey JG, Engelberts D, Kavanagh BP (2000) 'Buffering hypercapnic acidosis worsens acute lung injury'. Critical Care Medicine, 161 (1):141-146 [Details]
(2000) 'Therapeutic hypercapnia reduces pulmonary and systemic injury following in vivo lung reperfusion'
Laffey JG, Tanaka M, Engelberts D, Luo X, Yuan S, Tanswell AK, Post M, Lindsay T, Kavanagh BP (2000) 'Therapeutic hypercapnia reduces pulmonary and systemic injury following in vivo lung reperfusion'. Critical Care Medicine, 162 (6):2287-2294 [Details]
(2000) 'Adverse ventilatory strategy causes pulmonary-to-systemic translocation of endotoxin'
Murphy DB, Cregg N, Tremblay L, Engelberts D, Laffey JG, Slutsky AS, Romaschin A, Kavanagh BP (2000) 'Adverse ventilatory strategy causes pulmonary-to-systemic translocation of endotoxin'. Critical Care Medicine, 162 (1):27-33 [Details]
(2000) 'Injurious effects of Hypocapnic Alkalosis in the Lung'
Engelberts D, Kavanagh BP, Laffey JG (2000) 'Injurious effects of Hypocapnic Alkalosis in the Lung'. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDIC, :399-405 [Details]
(2000) 'Patients' knowledge of perioperative care'
Laffey JG, Coleman M, Boylan JF (2000) 'Patients' knowledge of perioperative care'. Ir J Med Sci, 169 (2):113-118 [Details]
(2000) 'Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury'
Laffey JG, Kavanagh BP (2000) 'Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury'. The New England journal of medicine, 343 (11):1-4 [DOI] [Details]
(2000) 'The effects of intracuff lidocaine on endotracheal-tube-induced emergence phenomena after general anesthesia'
Fagan C, Frizelle HP, Laffey J, Hannon V, Carey M (2000) 'The effects of intracuff lidocaine on endotracheal-tube-induced emergence phenomena after general anesthesia'. Anesthesia And Analgesia, 91 (1):201-205 [Details]
(2000) 'Biological effects of hypercapnia'
Laffey JG, Kavanagh BP (2000) 'Biological effects of hypercapnia'. Intensive care medicine, 26 (1):133-138 [Details]
(1999) 'Carbon dioxide and the critically ill--too little of a good thing?'
Laffey JG, Kavanagh BP (1999) 'Carbon dioxide and the critically ill--too little of a good thing?'. Lancet, 354 (9186):1283-1286 [DOI] [Details]
(1999) 'Efficacy of spinal cord stimulation for neuropathic pain following idiopathic acute transverse myelitis: a case report'
Laffey JG, Murphy D, Regan J, O'Keeffe D (1999) 'Efficacy of spinal cord stimulation for neuropathic pain following idiopathic acute transverse myelitis: a case report'. Clinical neurology and neurosurgery, 101 (2):125-127 [Details]
(1999) 'Prolonged perioperative myocardial ischemia in a young male: due to topical intranasal cocaine?'
Laffey JG, Neligan P, Ormonde G (1999) 'Prolonged perioperative myocardial ischemia in a young male: due to topical intranasal cocaine?'. Journal Of Clinical Anesthesia, 11 (5):419-424 [Details]
(1998) 'Instructions for ambulatory surgery--patient comprehension and compliance'
Laffey JG, Carroll M, Donnelly N, Boylan JF (1998) 'Instructions for ambulatory surgery--patient comprehension and compliance'. Ir J Med Sci, 167 (3):160-163 [Details]
(1998) 'Cost-benefit analysis of spinal cord stimulation for intractable angina pectoris: a win-win scenario?'
Laffey J, Murphy D, Regan J, O'Keeffe D (1998) 'Cost-benefit analysis of spinal cord stimulation for intractable angina pectoris: a win-win scenario?'. Hospital Medicine, 59 (10):820-821 [Details]

Book Chapters

  Year Publication
(2016) 'Obstetric physiology and special considerations in ICU'
Neligan P, Laffey JG (2016) 'Obstetric physiology and special considerations in ICU' In: Oxford Textbook of Critical Care. UK: Oxford University Press (Publication Spring 2016). [Details]
(2016) 'Hypercapnia (Acute Respiratory Failure)'
Laffey JG, Kavanagh BP (2016) 'Hypercapnia (Acute Respiratory Failure)' In: Oxford Textbook of Critical Care. UK: Oxford University Press (Publication Spring 2016). [Details]
(2015) 'Is Permissive Hypercapnia helpful or harmful?'
Contreras M, Laffey JG (2015) 'Is Permissive Hypercapnia helpful or harmful?' In: Evidence-Based Practice of Critical Care. Canada: Elselvier (Published Autumn 2015). [Details]
(2015) 'Hypocapnia and Hypercapniaa'
Curley G, Kavanagh BP, Laffey JG, (2015) 'Hypocapnia and Hypercapniaa' In: Murray & Nadel’s Textbook of Respiratory Medicine (6th Edition). USA: Elsevier Companies Inc (Published Autumn 2015). [Details]
(2014) 'Pediatric Critical Care'
Hassett P, Laffey JG, Kavanagh BP (2014) 'Pediatric Critical Care' In: Permissive Hypercapnia. Germany: Springer-Verlag (Published Spring 2014). [Details]
(2014) 'Mechanical Ventilation, Permissive Hypercapnia'
Contreras M, Laffey JG, Kavanagh BP (2014) 'Mechanical Ventilation, Permissive Hypercapnia' In: Encyclopedia of Trauma Care. UK: Springer Companies Inc (Publication Autumn 2014). [Details]
(2013) 'Mesenchymal Stem/Stromal cells: Opportunities and Obstacles in ARDS'
Curley G, Hayes M, Laffey JG (2013) 'Mesenchymal Stem/Stromal cells: Opportunities and Obstacles in ARDS' In: Yearbook of Intensive Care and Emergency Medicine. Germany: Springer-Verlag (Published Spring 2013). [Details]
(2012) 'Permissive Hypercapnia'
Laffey J.G, Kavanagh, B.P. (2012) 'Permissive Hypercapnia' In: Principles & Practice of Mechanical Ventilation. US: McGraw-Hill Companies Inc. [Details]
(2011) 'Acute Respiratory Distress Syndrome'
Walshe C, Kevin L, Laffey JG, Kavanagh BP (2011) 'Acute Respiratory Distress Syndrome' In: Postoperative Cardiac Care. A Society of Cardiovascular Anesthesiologists Monograph. Baltimore, US: Lippincott Williams & Wilkins. [Details]
(2011) 'Can ‘permissive’ hypercapnia modulate sepsis induced ALI/ARDS?'
Curley G, Hayes M, Laffey JG (2011) 'Can ‘permissive’ hypercapnia modulate sepsis induced ALI/ARDS?' In: 2011 Yearbook of Intensive Care and Emergency Medicine. Belgium: Springer-Verlag. [Details]
(2009) 'Permissive Hypercapnia'
Hassett P, Laffey JG (2009) 'Permissive Hypercapnia' In: Il Malato Critico. (The Critically Ill Patient.). Torino, Italy: UTET Scienze Mediche. [Details]
(2009) 'Is Permissive Hypercapnia helpful or harmful?'
Contreras M, Hassett P, Laffey JG. (2009) 'Is Permissive Hypercapnia helpful or harmful?' In: Evidence-Based Practice of Critical Care. United States: Elselvier. [Details]
(2008) 'Hypercapnia – Permissive, Therapeutic or not at all?'
Contreras M, Hassett P, Laffey JG (2008) 'Hypercapnia – Permissive, Therapeutic or not at all?' In: 2008 Yearbook of Intensive Care and Emergency Medicine. Belgium: Springer-Verlag. [Details]
(2006) 'Permissive Hypercapnia'
Laffey JG, Kavanagh BP. (2006) 'Permissive Hypercapnia' In: Principles & Practice of Mechanical Ventilation. New York, US: McGraw-Hill Companies Inc. [Details]
(2006) 'Modulation of Lung Injury by Hypercapnia'
Laffey JG, Kavanagh BP (2006) 'Modulation of Lung Injury by Hypercapnia' In: Ventilator-Induced Lung injury (Series on Lung Biology in Health and Disease). New York, US: Marcel Dekker Inc. [Details]
(2006) 'Permissive Hypercapnia: Role in Protective Lung ventilatory strategies'
Laffey JG, O'Croinin D, McLoughlin P, Kavanagh BP. (2006) 'Permissive Hypercapnia: Role in Protective Lung ventilatory strategies' In: Applied Physiology in Intensive Care. Berlin, Germany: Springer Verlag. [Details]
(2006) 'Analgesia following Caesarean Section'
Farragher R, Laffey JG. (2006) 'Analgesia following Caesarean Section' In: Postoperative Pain Management: An Evidence-Based Guide to Practice. Amsterdam, The Netherlands: Elsevier Press Inc. [Details]

Conference Publications

  Year Publication
(2020) INTENSIVE CARE MEDICINE EXPERIMENTAL
Brady, J;Horie, S;Laffey, JG (2020) Role of the adaptive immune response in sepsis INTENSIVE CARE MEDICINE EXPERIMENTAL [DOI] [Details]
(2019) HUMAN SYSTEMS ENGINEERING AND DESIGN, IHSED2018
Andrade, E;Quinlan, LR;Harte, R;Byrne, D;Fallon, E;Kelly, M;O'Connor, P;O'Hora, D;Scully, M;Laffey, J;Pladys, P;Beuchee, A;OLaighin, G (2019) State of the Art and Future Trends in the Usability of Patient Monitors HUMAN SYSTEMS ENGINEERING AND DESIGN, IHSED2018 , pp.338-344 [DOI] [Details]
(2019) Investigation of the Human Factors, Usability and User Experience of Patient Monitors used in a Hospital Setting
Andrade, E,Quinlan, LR,Harte, R,Byrne, D,Fallon, E,Kelly, M,O'Connor, P,O'Hora, D,Scully, M,Laffey, J,Pladys, P,Beuchee, A,OLaighin, G,Ahram, T,Karwowski, W,Taiar, R (2019) HUMAN SYSTEMS ENGINEERING AND DESIGN, IHSED2018 Investigation of the Human Factors, Usability and User Experience of Patient Monitors used in a Hospital Setting , pp.352-357 [DOI] [Details]
(2019) State of the Art and Future Trends in the Usability of Patient Monitors
Andrade, E,Quinlan, LR,Harte, R,Byrne, D,Fallon, E,Kelly, M,O'Connor, P,O'Hora, D,Scully, M,Laffey, J,Pladys, P,Beuchee, A,OLaighin, G,Ahram, T,Karwowski, W,Taiar, R (2019) HUMAN SYSTEMS ENGINEERING AND DESIGN, IHSED2018 State of the Art and Future Trends in the Usability of Patient Monitors , pp.338-344 [DOI] [Details]
(2005) ANESTHESIA AND ANALGESIA
Maharaj, CH;Kallam, SR;Malik, A;Hassett, P;Grady, D;Laffey, JG (2005) Preoperative intravenous fluid therapy decreases postoperative nausea and pain in high risk patients ANESTHESIA AND ANALGESIA , pp.675-682 [DOI] [Details]
(2007) ANESTHESIA AND ANALGESIA
McDonnell, JG;O'Donnell, B;Curley, G;Heffernan, A;Power, C;Laffey, JG (2007) The analgesic efficacy of transversus abdominis plane block after abdominal surgery: A prospective randomized controlled trial ANESTHESIA AND ANALGESIA , pp.193-197 [DOI] [Details]
(2008) ANAESTHESIA
Maharaj, CH;Costello, JF;Harte, BH;Laffey, JG (2008) Evaluation of the Airtraq (R) and Macintosh laryngoscopes in patients at increased risk for difficult tracheal intubation ANAESTHESIA , pp.182-188 [DOI] [Details]
(2008) ANESTHESIOLOGY
Chonghaile, MN;Higgins, BD;Costello, J;Laffey, JG (2008) Hypercapnic Acidosis Attenuates Lung Injury Induced by Established Bacterial Pneumonia ANESTHESIOLOGY , pp.837-848 [Details]
(2009) CRITICAL CARE MEDICINE
Costello, J;Higgins, B;Contreras, M;Chonghaile, MN;Hassett, P;O'Toole, D;Laffey, JG (2009) Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis CRITICAL CARE MEDICINE , pp.2412-2420 [DOI] [Details]
(2010) BIOSIGNALS 2010: PROCEEDINGS OF THE THIRD INTERNATIONAL CONFERENCE ON BIO-INSPIRED SYSTEMS AND SIGNAL PROCESSING
Enright, C.G.; Madden, M.G.; Russell, S., Aleks, N.; Manley, G.; Laffey, J.; Harte, B.; Mulvey, A.; Madden, N.; Fred, A.; Filipe, J.; Gamboa, H. (2010) Modelling Glycaemia in ICU Patients - A Dynamic Bayesian Network Approach BIOSIGNALS 2010: PROCEEDINGS OF THE THIRD INTERNATIONAL CONFERENCE ON BIO-INSPIRED SYSTEMS AND SIGNAL PROCESSING , pp.452-459 [Details]
(2010) BIOSIGNALS 2010: PROCEEDINGS OF THE THIRD INTERNATIONAL CONFERENCE ON BIO-INSPIRED SYSTEMS AND SIGNAL PROCESSING
Enright, CG;Madden, MG;Russell, S;Aleks, N;Manley, G;Laffey, J;Harte, B;Mulvey, A;Madden, N (2010) MODELLING GLYCAEMIA IN ICU PATIENTS A Dynamic Bayesian Network Approach BIOSIGNALS 2010: PROCEEDINGS OF THE THIRD INTERNATIONAL CONFERENCE ON BIO-INSPIRED SYSTEMS AND SIGNAL PROCESSING , pp.452-459 [Details]
(2011) INTENSIVE CARE MEDICINE
Hassett, P;Curley, GF;Contreras, M;Masterson, C;Higgins, BD;O'Brien, T;Devaney, J;O'Toole, D;Laffey, JG (2011) Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury INTENSIVE CARE MEDICINE , pp.1680-1687 [DOI] [Details]
(2011) Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury
Hassett, P,Curley, GF,Contreras, M,Masterson, C,Higgins, BD,O'Brien, T,Devaney, J,O'Toole, D,Laffey, JG (2011) INTENSIVE CARE MEDICINE Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury , pp.1680-1687 [DOI] [Details]
(2009) Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis
Costello, J,Higgins, B,Contreras, M,Chonghaile, MN,Hassett, P,O'Toole, D,Laffey, JG (2009) CRITICAL CARE MEDICINE Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis , pp.2412-2420 [DOI] [Details]
(2008) Hypercapnic Acidosis Attenuates Lung Injury Induced by Established Bacterial Pneumonia
Chonghaile, MN,Higgins, BD,Costello, J,Laffey, JG (2008) ANESTHESIOLOGY Hypercapnic Acidosis Attenuates Lung Injury Induced by Established Bacterial Pneumonia , pp.837-848 [Details]
(2008) Society of Pediatric Anesthesia 2008 Winter Symposium
Laffey JG (2008) Hypercapnia: Permissive and Therapeutic Society of Pediatric Anesthesia 2008 Winter Symposium [Details]
(2008) Proceedings of the 14th Annual Conference of the Section of Bioengineering of Royal Academy of Medicine in Ireland
Heraty, K.B., Laffey, J.G., Quinlan, N.J. (2008) Fluid dynamics of gas exchange in high frequency oscillatory ventilation . In: Reilly, G.; Fitzpatrick, D eds. Proceedings of the 14th Annual Conference of the Section of Bioengineering of Royal Academy of Medicine in Ireland Sligo, Ireland, , 25-JAN-08 - 26-JAN-08 [Details]
(2008) Evaluation of the Airtraq (R) and Macintosh laryngoscopes in patients at increased risk for difficult tracheal intubation
Maharaj, CH,Costello, JF,Harte, BH,Laffey, JG (2008) ANAESTHESIA Evaluation of the Airtraq (R) and Macintosh laryngoscopes in patients at increased risk for difficult tracheal intubation , pp.182-188 [DOI] [Details]
(2007) The analgesic efficacy of transversus abdominis plane block after abdominal surgery: A prospective randomized controlled trial
McDonnell, JG,O'Donnell, B,Curley, G,Heffernan, A,Power, C,Laffey, JG (2007) ANESTHESIA AND ANALGESIA The analgesic efficacy of transversus abdominis plane block after abdominal surgery: A prospective randomized controlled trial , pp.193-197 [DOI] [Details]
(2005) Preoperative intravenous fluid therapy decreases postoperative nausea and pain in high risk patients
Maharaj, CH,Kallam, SR,Malik, A,Hassett, P,Grady, D,Laffey, JG (2005) ANESTHESIA AND ANALGESIA Preoperative intravenous fluid therapy decreases postoperative nausea and pain in high risk patients , pp.675-682 [DOI] [Details]

Other Journals

  Year Publication
(2020) 'The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project'
Flynn, J; O'Connor, L; Hanlon, M; Bellani, G; Conteras, M; Doherty, A; Durand, H; Fallon, E; Gormley, C; Laffey, J; Molloy, GJ; Sarma, K; Strepparava, MG; Russo, S; Walsh, JE; McGuire, BE. (2020) 'The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project' HRB Open, . [DOI] [Details]
(2004) 'The inflammatory response to Surgery'
Laffey JG (2004) 'The inflammatory response to Surgery' Proceedings of the 2004 Annual Winter Anaesthesia Symposium, . [Details]
(2003) 'The role of permissive hypercapnia in a concept of protective lung ventilation'
Laffey JG (2003) 'The role of permissive hypercapnia in a concept of protective lung ventilation' Journal fur Anasthesie und Intensivbehandlung, :100-102. [Details]
(2003) 'Permissive Hypercapnia – with or without Acidosis?'
Laffey JG (2003) 'Permissive Hypercapnia – with or without Acidosis?' Journal fur Anasthesie und Intensivbehandlung, :157-158. [Details]
(2003) 'Perioperative ACE Inhibitors and Outcome'
Laffey JG (2003) 'Perioperative ACE Inhibitors and Outcome' Proceedings of the College of Anaesthetists RCSI Annual Scientific Meeting, :30-33. [Details]
(2003) 'Attenuation of the Stress response to Cardiac Surgery is Beneficial'
Laffey JG (2003) 'Attenuation of the Stress response to Cardiac Surgery is Beneficial' Society of Cardiovascular Anaesthesia Newsletter, . [Details]

Abstract

  Year Publication
(2011) HUMAN MESENCHYMAL STEM CELL-CONDITIONED MEDIUM IS PROTECTIVE IN STRETCH-INDUCED LUNG INJURY.
Ansari, RM,Curley, GF,O'Toole, DP,Laffey, JG (2011) HUMAN MESENCHYMAL STEM CELL-CONDITIONED MEDIUM IS PROTECTIVE IN STRETCH-INDUCED LUNG INJURY. Abstract [Details]
(2011) MESENCHYMAL STEM CELLS AND MESENCHYMAL STEM CELL CONDITIONED MEDIUM ACCELERATE ALVEOLAR EPITHELIAL WOUND HEALING IN AN IN VITRO WOUND SCRATCH MODEL.
Curley, GF,McHale, P,Hayes, M,Ansari, B,Masterson, C,Devaney, J,O'Toole, D,Laffey, JG (2011) MESENCHYMAL STEM CELLS AND MESENCHYMAL STEM CELL CONDITIONED MEDIUM ACCELERATE ALVEOLAR EPITHELIAL WOUND HEALING IN AN IN VITRO WOUND SCRATCH MODEL. Abstract [Details]
(2011) MESENCHYMAL STEM CELLS ATTENUATE LUNG INJURY SEVERITY IN AN ACUTE REPAIR MODEL OF VENTILATOR INDUCED LUNG INJURY.
Hayes, M,Curley, G,O'Toole, D,Laffey, JG (2011) MESENCHYMAL STEM CELLS ATTENUATE LUNG INJURY SEVERITY IN AN ACUTE REPAIR MODEL OF VENTILATOR INDUCED LUNG INJURY. Abstract [Details]
(2012) HUMAN MESENCHYMAL STEM CELLS ENHANCE REPAIR FOLLOWING VENTILATOR-INDUCED LUNG INJURY.
Hayes, MB,Ansari, B,Curley, G,Elliman, S,O'Toole, D,Laffey, JG (2012) HUMAN MESENCHYMAL STEM CELLS ENHANCE REPAIR FOLLOWING VENTILATOR-INDUCED LUNG INJURY. Abstract [Details]
(2013) Hypercapnic acidosis reduces stretch-induced inflammation in alveolar epithelial cells by an NF-kappa B dependent mechanism.
Ansari, BM,Contreras, M,Curley, GF,Masterson, CH,McHale, PM,Hayes, M,O'Toole, DP,Laffey, JG (2013) Hypercapnic acidosis reduces stretch-induced inflammation in alveolar epithelial cells by an NF-kappa B dependent mechanism. Abstract [Details]
(2013) Assessing The Therapeutic Potential Of Induced Pluripotent Stem Cells In In Vitro Models Of Acute Lung Injury. American Thoracic Society International Conference. 2013, Philadelphia.
O'Toole D, Horie S, McDonagh K, Masterson CH, Shen S, Laffey JG. (2013) Assessing The Therapeutic Potential Of Induced Pluripotent Stem Cells In In Vitro Models Of Acute Lung Injury. American Thoracic Society International Conference. 2013, Philadelphia. Abstract [Details]
(2015) Bile Acids Cause Direct Inflammation and Injury and Worsen Acid Induced Injury in the Pulmonary Epithelium.
McDonnell, MJ,O'Toole, D,Rutherford, R,De Soyza, A,Lordan, J,Pearson, J,Ward, C,Laffey, JG (2015) Bile Acids Cause Direct Inflammation and Injury and Worsen Acid Induced Injury in the Pulmonary Epithelium. Abstract [Details]
(2015) Azithromycin Attenuates Release of Bile Acid-Mediated Neutrophilic and Remodelling Factors from Human Bronchial Epithelial Cells.
McDonnell, MJ,O'Toole, D,Rutherford, R,De Soyza, A,Lordan, J,Pearson, J,Ward, C,Laffey, JG (2015) Azithromycin Attenuates Release of Bile Acid-Mediated Neutrophilic and Remodelling Factors from Human Bronchial Epithelial Cells. Abstract [Details]
(2014) Selection of optimum Baska mask size in male patients, an initial study.
Alexiev, V,Ochana, A,Quinn, A,Foto, T,McDonnell, JG,Laffey, JG (2014) Selection of optimum Baska mask size in male patients, an initial study. Abstract [Details]
(2009) Lung Injury and is Impact in ACS.
Laffey, JG (2009) Lung Injury and is Impact in ACS. Abstract [Details]
(2009) INTRAPULMONARY DELIVERY OF EXTRACELLULAR SUPEROXIDE DISMUTASE AMELIORATES LIPO-POLYSACCHARIDE INDUCED LUNG INJURY IN RATS.
Hassett, P,Curley, G,O'Toole, D,O'Higgins, B,Laffey, J (2009) INTRAPULMONARY DELIVERY OF EXTRACELLULAR SUPEROXIDE DISMUTASE AMELIORATES LIPO-POLYSACCHARIDE INDUCED LUNG INJURY IN RATS. Abstract [Details]
(2008) Aerosol delivery of rAAV pseudotypes 2, 2/5 and 2/6. ISGCT Annual Conference.
MacLoughlin R, Higgins B, Laffey J, O'Brien T (2008) Aerosol delivery of rAAV pseudotypes 2, 2/5 and 2/6. ISGCT Annual Conference. UCC: Abstract [Details]
(2007) Optimization of aerosol delivery to the lungs of Sprague-Dawley rat, an in vitro study of aerosol performance. International Society for Aerosols in Medicine (ISAM), 16th Congress, Vinci Congress Center.
MacLoughlin R, Higgins B, Laffey J, O' Brien T (2007) Optimization of aerosol delivery to the lungs of Sprague-Dawley rat, an in vitro study of aerosol performance. International Society for Aerosols in Medicine (ISAM), 16th Congress, Vinci Congress Center. Tours, France: Abstract [Details]
(2007) A systematic approach to maximising aerosol delivery of adeno-associated viral (AAV) vector to the lungs. British Association for Lung Research (BALR), 'Gene and Stem Cell Therapies for Lung Diseases', National University of Ireland, Maynooth, Ireland.
MacLoughlin R, Higgins B, Laffey J, O'Brien T (2007) A systematic approach to maximising aerosol delivery of adeno-associated viral (AAV) vector to the lungs. British Association for Lung Research (BALR), 'Gene and Stem Cell Therapies for Lung Diseases', National University of Ireland, Maynooth, Ireland. Abstract [Details]

ANET/COS

  Year Publication
(2013) ‘The critically ill pregnant patient'. SMART Conference Milan.
Laffey JG (2013) ‘The critically ill pregnant patient'. SMART Conference Milan. ANET/COS [Details]

Book Review

  Year Publication
(2019) Therapeutic Potential of Mesenchymal Stem Cells to combat immune cell tolerance in a late stage model of sepsis.
Byrnes, D,Masterson, C,Horie, S,McCarthy, S,O'Toole, D,Laffey, J (2019) Therapeutic Potential of Mesenchymal Stem Cells to combat immune cell tolerance in a late stage model of sepsis. Book Review [Details]

Conference Paper

  Year Publication
(2006) Session chair – ESICM Conference.
J.G. Laffey (2006) Session chair – ESICM Conference. Conference Paper [Details]
(2005) Succeeding in Basic Science Research. Intensive Care society Winter Meeting .
J.G. Laffey (2005) Succeeding in Basic Science Research. Intensive Care society Winter Meeting . Belfast, Northern Ireland: Conference Paper [Details]
(2004) Symposium Co-Chairman, Session ‘Mechanical Ventilation: New Experimental Insights’, Annual Scientific Meeting, American Thoracic Society.
J.G. Laffey (2004) Symposium Co-Chairman, Session ‘Mechanical Ventilation: New Experimental Insights’, Annual Scientific Meeting, American Thoracic Society. Conference Paper [Details]
(2003) Chairman, Ventilation Session, Autumn Scientific Meeting, Intensive Care Society of Ireland .
J.G. Laffey (2003) Chairman, Ventilation Session, Autumn Scientific Meeting, Intensive Care Society of Ireland . Galway, Ireland: Conference Paper [Details]
(2003) Permissive Hypercapnia – with or without Acidosis?'.
J.G. Laffey (2003) Permissive Hypercapnia – with or without Acidosis?'. Bremen, Germany: Conference Paper [Details]
(2003) 'The role of permissive hypercapnia in Protective Lung Ventilation strategies'. HAI 2003 Congress.
J.G. Laffey (2003) 'The role of permissive hypercapnia in Protective Lung Ventilation strategies'. HAI 2003 Congress. Berlin, Germany: Conference Paper [Details]
(2003) Scientific Programme Chair, 2003 West of Ireland Symposium in Anaesthesia .
J.G. Laffey (2003) Scientific Programme Chair, 2003 West of Ireland Symposium in Anaesthesia . Galway, Ireland: Conference Paper [Details]
(2001) Managing Care – Is there a role for step-down units?' .
J.G. Laffey (2001) Managing Care – Is there a role for step-down units?' . Geneva, Switzerland: Conference Paper [Details]

Editorial

  Year Publication
(2020) Meta-trial of awake prone positioning with nasal high flow therapy: Invitation to join a pandemic collaborative research effort.
Li, J;Pavlov, I;Laffey, JG;Roca, O;Mirza, S;Perez, Y;McNicholas, B;Cosgrave, D;Vines, D;Tavernier, E;Ehrmann, S (2020) Meta-trial of awake prone positioning with nasal high flow therapy: Invitation to join a pandemic collaborative research effort. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC Editorial [DOI] [Details]
(2020) Machine Learning Classifier Models: The Future for Acute Respiratory Distress Syndrome Phenotyping?.
McNicholas, B;Madden, MG;Laffey, JG (2020) Machine Learning Classifier Models: The Future for Acute Respiratory Distress Syndrome Phenotyping?. NEW YORK: AMER THORACIC SOC Editorial [DOI] [Details]
(2020) Machine Learning Classifier Models: The Future for Acute Respiratory Distress Syndrome Phenotyping?.
McNicholas, B,Madden, MG,Laffey, JG (2020) Machine Learning Classifier Models: The Future for Acute Respiratory Distress Syndrome Phenotyping?. Editorial [DOI] [Details]
(2020) Supporting more than one patient with a single mechanical ventilator: useful last resort or unjustifiable risk?.
Laffey, JG;Chikhani, M;Bates, DG;Hardman, JG (2020) Supporting more than one patient with a single mechanical ventilator: useful last resort or unjustifiable risk?. OXFORD: ELSEVIER SCI LTD Editorial [Details]
(2020) Supporting more than one patient with a single mechanical ventilator: useful last resort or unjustifiable risk?.
Laffey, JG,Chikhani, M,Bates, DG,Hardman, JG (2020) Supporting more than one patient with a single mechanical ventilator: useful last resort or unjustifiable risk?. Editorial [Details]
(2020) Prone positioning in COVID-19 acute respiratory failure: just do it?.
McNicholas, B;Cosgrave, D;Giacomini, C;Brennan, A;Laffey, JG (2020) Prone positioning in COVID-19 acute respiratory failure: just do it?. OXFORD: ELSEVIER SCI LTD Editorial [DOI] [Details]
(2020) Prone positioning in COVID-19 acute respiratory failure: just do it?.
McNicholas, B,Cosgrave, D,Giacomini, C,Brennan, A,Laffey, JG (2020) Prone positioning in COVID-19 acute respiratory failure: just do it?. Editorial [DOI] [Details]
(2020) Paediatric emergency front-of-neck access: accuracy of cricothyroid membrane identification and hypothetical incision lengths.
Walsh, B,Fennessy, P,Laffey, J,McCarthy, K,McCaul, C (2020) Paediatric emergency front-of-neck access: accuracy of cricothyroid membrane identification and hypothetical incision lengths. Editorial [Details]
(2020) The importance of discovery science in the development of therapies for the critically ill.
Juffermans, NP;Radermacher, P;Laffey, JG (2020) The importance of discovery science in the development of therapies for the critically ill. NEW YORK: SPRINGER Editorial [DOI] [Details]
(2020) The importance of discovery science in the development of therapies for the critically ill.
Juffermans, NP,Radermacher, P,Laffey, JG (2020) The importance of discovery science in the development of therapies for the critically ill. Editorial [DOI] [Details]
(2019) What's new in airway management of the critically ill.
Russotto, V;Myatra, SN;Laffey, JG (2019) What's new in airway management of the critically ill. NEW YORK: SPRINGER Editorial [DOI] [Details]
(2019) What's new in airway management of the critically ill.
Russotto, V,Myatra, SN,Laffey, JG (2019) What's new in airway management of the critically ill. Editorial [DOI] [Details]
(2007) Permissive hypercapnia: Balancing risks and benefits in the peripheral micro circulation.
Hassett, P;Laffey, JG (2007) Permissive hypercapnia: Balancing risks and benefits in the peripheral micro circulation. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Editorial [DOI] [Details]
(2007) Implementing scientific advances into clinical practice in critical care - New challenges and new insights.
Costello, JF;Laffey, JG (2007) Implementing scientific advances into clinical practice in critical care - New challenges and new insights. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Editorial [DOI] [Details]
(2008) Carbon monoxide - From poison to therapy for cardiopulmonary bypass-induced lung injury?.
Kevin, LG;Laffey, JG (2008) Carbon monoxide - From poison to therapy for cardiopulmonary bypass-induced lung injury?. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Editorial [Details]
(2009) Mechanical Ventilation Taking Its Toll on the Lung.
Curley, GF;Kevin, LG;Laffey, JG (2009) Mechanical Ventilation Taking Its Toll on the Lung. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Editorial [Details]
(2011) Strengthening the evidence base for airway equipment: time to be more 'ADEPT'?.
Laffey, JG (2011) Strengthening the evidence base for airway equipment: time to be more 'ADEPT'?. MALDEN: WILEY-BLACKWELL Editorial [DOI] [Details]
(2011) Casual bystander or active participant? New clues about adiponectin and traumatic injury.
White, M;Laffey, JG;Kevin, LG (2011) Casual bystander or active participant? New clues about adiponectin and traumatic injury. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Editorial [DOI] [Details]
(2011) Hypocapnia induced cerebral ischaemia during therapeutic hypothermia-Potential for harm?.
Curley, G;Laffey, JG (2011) Hypocapnia induced cerebral ischaemia during therapeutic hypothermia-Potential for harm?. CLARE: ELSEVIER IRELAND LTD Editorial [DOI] [Details]
(2011) A rude awakening after our fourth 'NAP': lessons for airway management.
O'Sullivan, E;Laffey, J;Pandit, JJ (2011) A rude awakening after our fourth 'NAP': lessons for airway management. HOBOKEN: WILEY-BLACKWELL Editorial [DOI] [Details]
(2012) Ischemia-reperfusion-induced lung injury: Could hypercapnia have a therapeutic role?.
Ansari, B;Laffey, JG (2012) Ischemia-reperfusion-induced lung injury: Could hypercapnia have a therapeutic role?. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Editorial [DOI] [Details]
(2016) What's new in cell therapies in ARDS?.
Horie, S,Curley, GF,Laffey, JG (2016) What's new in cell therapies in ARDS?. Editorial [DOI] [Details]
(2017) EASILY MISSED? Acute respiratory distress syndrome.
Laffey, JG,Misak, C,Kavanagh, BP (2017) EASILY MISSED? Acute respiratory distress syndrome. Editorial [DOI] [Details]
(2018) Negative trials in critical care: why most research is probably wrong.
Laffey, JG,Kavanagh, BP (2018) Negative trials in critical care: why most research is probably wrong. Editorial [DOI] [Details]
(2019) Sepsis: Therapeutic Potential of Immunosuppression versus Immunostimulation.
Rezoagli, E,Masterson, CH,McCarthy, SD,Laffey, JG (2019) Sepsis: Therapeutic Potential of Immunosuppression versus Immunostimulation. Editorial [DOI] [Details]
(2019) The worldwide assessment of separation of patients from ventilatory assistance (WEAN SAFE) ERS Clinical Research Collaboration.
Heunks, L;Bellani, G;Pham, T;Brochard, L;Laffey, JG (2019) The worldwide assessment of separation of patients from ventilatory assistance (WEAN SAFE) ERS Clinical Research Collaboration. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD Editorial [DOI] [Details]
(2012) Ischemia-reperfusion-induced lung injury: Could hypercapnia have a therapeutic role?.
Ansari, B,Laffey, JG (2012) Ischemia-reperfusion-induced lung injury: Could hypercapnia have a therapeutic role?. Editorial [DOI] [Details]
(2011) Hypocapnia induced cerebral ischaemia during therapeutic hypothermia-Potential for harm?.
Curley, G,Laffey, JG (2011) Hypocapnia induced cerebral ischaemia during therapeutic hypothermia-Potential for harm?. Editorial [DOI] [Details]
(2011) Casual bystander or active participant? New clues about adiponectin and traumatic injury.
White, M,Laffey, JG,Kevin, LG (2011) Casual bystander or active participant? New clues about adiponectin and traumatic injury. Editorial [DOI] [Details]
(2011) A rude awakening after our fourth 'NAP': lessons for airway management.
O'Sullivan, E,Laffey, J,Pandit, JJ (2011) A rude awakening after our fourth 'NAP': lessons for airway management. Editorial [DOI] [Details]
(2011) Strengthening the evidence base for airway equipment: time to be more 'ADEPT'?.
Laffey, JG (2011) Strengthening the evidence base for airway equipment: time to be more 'ADEPT'?. Editorial [DOI] [Details]
(2009) Mechanical Ventilation Taking Its Toll on the Lung.
Curley, GF,Kevin, LG,Laffey, JG (2009) Mechanical Ventilation Taking Its Toll on the Lung. Editorial [Details]
(2008) Carbon monoxide - From poison to therapy for cardiopulmonary bypass-induced lung injury?.
Kevin, LG,Laffey, JG (2008) Carbon monoxide - From poison to therapy for cardiopulmonary bypass-induced lung injury?. Editorial [Details]
(2007) Permissive hypercapnia: Balancing risks and benefits in the peripheral micro circulation.
Hassett, P,Laffey, JG (2007) Permissive hypercapnia: Balancing risks and benefits in the peripheral micro circulation. Editorial [DOI] [Details]
(2007) Implementing scientific advances into clinical practice in critical care - New challenges and new insights.
Costello, JF,Laffey, JG (2007) Implementing scientific advances into clinical practice in critical care - New challenges and new insights. Editorial [DOI] [Details]

Invited Lectures

  Year Publication
(2017) Cell based therapies for ARDS: Where are we now?, at China-Canada-USA Pharmacology/Physiology Conference, Univ of Toronto.
Laffey JG (2017) Cell based therapies for ARDS: Where are we now?, at China-Canada-USA Pharmacology/Physiology Conference, Univ of Toronto. Invited Lectures [Details]
(2017) ‘Current global practices in mechanical ventilation for ARDS’ at Critical Care Canada Conference on Mechanical Ventilation, Toronto.
Laffey JG (2017) ‘Current global practices in mechanical ventilation for ARDS’ at Critical Care Canada Conference on Mechanical Ventilation, Toronto. Invited Lectures [Details]
(2017) ‘Hypercapnia: should we permit, remove or induce? ’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2017) ‘Hypercapnia: should we permit, remove or induce? ’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2017) ‘Is ARDS really different from other forms of acute hypoxemic respiratory failure?’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2017) ‘Is ARDS really different from other forms of acute hypoxemic respiratory failure?’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2017) ‘Stem Cells for ARDS’ at Canadian Critical Care Forum, Toronto.
Laffey JG (2017) ‘Stem Cells for ARDS’ at Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2017) ‘Cell-based therapies for Sepsis’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Invited talk ‘Cell-based therapies for Sepsis’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels (2017) ‘Cell-based therapies for Sepsis’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2017) ‘Non-invasive ventilation in ARDS’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2017) ‘Non-invasive ventilation in ARDS’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2017) ‘Extracorporeal CO2 Removal for COPD: Standard of care or fools gold’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2017) ‘Extracorporeal CO2 Removal for COPD: Standard of care or fools gold’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2017) ‘Cell-based therapies for ARDS’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2017) ‘Cell-based therapies for ARDS’ at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2016) ‘Lessons from LUNG SAFE’ at Canadian Critical Care Forum, Toronto.
Laffey JG (2016) ‘Lessons from LUNG SAFE’ at Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2016) ‘What can I learn from Lung Injury Models’ at European Society of Intensive Care Medicine Annual conference, Milan.
Laffey JG (2016) ‘What can I learn from Lung Injury Models’ at European Society of Intensive Care Medicine Annual conference, Milan. Invited Lectures [Details]
(2016) ‘LUNG SAFE: Regional variations and factors contributing to patient outcome from ARDS’ at European Society of Intensive Care Medicine Annual conference, Milan.
Laffey JG (2016) ‘LUNG SAFE: Regional variations and factors contributing to patient outcome from ARDS’ at European Society of Intensive Care Medicine Annual conference, Milan. Invited Lectures [Details]
(2016) ‘Acute hypoxaemic respiratory failure: different from ARDS’ at European Society of Intensive Care Medicine Annual conference, Milan.
Laffey JG (2016) ‘Acute hypoxaemic respiratory failure: different from ARDS’ at European Society of Intensive Care Medicine Annual conference, Milan. Invited Lectures [Details]
(2016) Invited commentary on RCT ‘Effect of postoperative high-flow nasal cannula vs conventional oxygen therapy on hypoxemia in patients after major abdominal surgery: A randomized clinical trial’ at European Society of Intensive Care Medicine Annual conference, Milan.
Laffey JG (2016) Invited commentary on RCT ‘Effect of postoperative high-flow nasal cannula vs conventional oxygen therapy on hypoxemia in patients after major abdominal surgery: A randomized clinical trial’ at European Society of Intensive Care Medicine Annual conference, Milan. Invited Lectures [Details]
(2016) ‘Oxygenation Targets in ARDS patients’ at European Society of Intensive Care Medicine Annual conference, Milan.
Laffey JG (2016) ‘Oxygenation Targets in ARDS patients’ at European Society of Intensive Care Medicine Annual conference, Milan. Invited Lectures [Details]
(2016) ‘Challenging clinical cases’ at International Conference in Anesthesia and Critical Care, Cong, Co Mayo.
Laffey JG (2016) ‘Challenging clinical cases’ at International Conference in Anesthesia and Critical Care, Cong, Co Mayo. Invited Lectures [Details]
(2016) ‘Acute Hypoxemic Respiratory Failure – Epidemiology Update’ at International Conference in Anesthesia and Critical Care, Cong, Co Mayo.
Laffey JG (2016) ‘Acute Hypoxemic Respiratory Failure – Epidemiology Update’ at International Conference in Anesthesia and Critical Care, Cong, Co Mayo. Invited Lectures [Details]
(2016) ‘Therapeutic efficacy of human mesenchymal cells (MSCs) in the repair of ARDS and VILI’ at European Respiratory Society Annual conference, London.
Laffey JG (2016) ‘Therapeutic efficacy of human mesenchymal cells (MSCs) in the repair of ARDS and VILI’ at European Respiratory Society Annual conference, London. Invited Lectures [Details]
(2016) ‘Mesenchymal cells (MSCs) for ARDS – translational challenges’ at European Respiratory Society Annual conference, London.
Laffey JG (2016) ‘Mesenchymal cells (MSCs) for ARDS – translational challenges’ at European Respiratory Society Annual conference, London. Invited Lectures [Details]
(2016) ‘ECMO in the 21st Century – Insights from the LUNG SAFE study’ at the ICS-ECMO Annual meeting, Paris , France.
Laffey JG (2016) ‘ECMO in the 21st Century – Insights from the LUNG SAFE study’ at the ICS-ECMO Annual meeting, Paris , France. Invited Lectures [Details]
(2016) ‘ARDS: Recommendations for Mechanical Ventilation’ at the University of Toronto Mechanical Ventilation Masterclass, Toronto.
Laffey JG (2016) ‘ARDS: Recommendations for Mechanical Ventilation’ at the University of Toronto Mechanical Ventilation Masterclass, Toronto. Invited Lectures [Details]
(2016) ‘ARDS and Acute Hypoxic Respiratory Failure – is there a difference’ at the SMART Annual meeting, Milan.
Laffey JG (2016) ‘ARDS and Acute Hypoxic Respiratory Failure – is there a difference’ at the SMART Annual meeting, Milan. Invited Lectures [Details]
(2016) ‘ARDS and Acute Hypoxic Respiratory Failure in the real world – what have we learned’ at the SMART Annual meeting, Milan.
Laffey JG (2016) ‘ARDS and Acute Hypoxic Respiratory Failure in the real world – what have we learned’ at the SMART Annual meeting, Milan. Invited Lectures [Details]
(2016) ‘Cell therapies for Pulmonary Diseases’ at the International Anesthesia Research Society Annual Scientific Meeting, San Francisco, US.
Laffey JG (2016) ‘Cell therapies for Pulmonary Diseases’ at the International Anesthesia Research Society Annual Scientific Meeting, San Francisco, US. Invited Lectures [Details]
(2016) ‘Severe Chest Trauma’ at European Society Annual Regional Conference, Porto, Portugal.
Laffey JG (2016) ‘Severe Chest Trauma’ at European Society Annual Regional Conference, Porto, Portugal. Invited Lectures [Details]
(2016) ‘Current clinical applications of stem cells for Critical Illnesses’ at Ontario Institute of Regenerative Medicine public symposium, Auditorium, Peter Gilgan Centre for Research and Learning, SickKids, Toronto.
Laffey JG (2016) ‘Current clinical applications of stem cells for Critical Illnesses’ at Ontario Institute of Regenerative Medicine public symposium, Auditorium, Peter Gilgan Centre for Research and Learning, SickKids, Toronto. Invited Lectures [Details]
(2016) SMH Critical Care Grand Rounds on ‘Epidemiology, patterns of care, and mortality for patients.
Laffey JG (2016) SMH Critical Care Grand Rounds on ‘Epidemiology, patterns of care, and mortality for patients. Invited Lectures [Details]
(2016) SMH Critical Care Grand Rounds on ‘Epidemiology, patterns of care, and mortality for patients.
Laffey JG (2016) SMH Critical Care Grand Rounds on ‘Epidemiology, patterns of care, and mortality for patients. Invited Lectures [Details]
(2016) ‘Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries’ at Society of Critical Care Medicine Annual Conference, Orlando.
Laffey JG (2016) ‘Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries’ at Society of Critical Care Medicine Annual Conference, Orlando. Invited Lectures [Details]
(2015) ‘Biomarkers for ARDS – not so simple’ at Canadian Critical Care Forum, Toronto.
Laffey JG (2015) ‘Biomarkers for ARDS – not so simple’ at Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2015) ‘How is lung protective ventilation implemented in real life: Lessons from the Lung SAFE study’ at 26th International SMART conference, Milan, Italy.
Laffey JG (2015) ‘How is lung protective ventilation implemented in real life: Lessons from the Lung SAFE study’ at 26th International SMART conference, Milan, Italy. Invited Lectures [Details]
(2015) ‘Hypercapnia and sepsis: Benefit or Harm?’ at 26th International SMART conference, Milan, Italy.
Laffey JG (2015) ‘Hypercapnia and sepsis: Benefit or Harm?’ at 26th International SMART conference, Milan, Italy. Invited Lectures [Details]
(2015) ‘Stem cells for ARDS’ at 26th International SMART conference, Milan, Italy.
Laffey JG (2015) ‘Stem cells for ARDS’ at 26th International SMART conference, Milan, Italy. Invited Lectures [Details]
(2015) ‘ARDS in the 21st Century’ delivered at Shields Day, Toronto.
Laffey JG (2015) ‘ARDS in the 21st Century’ delivered at Shields Day, Toronto. Invited Lectures [Details]
(2015) ‘Cardiovascular effects of Hypercapnia’ delivered at ESICM Summer Conference on Heart-Lung Interactions’, Dublin, Ireland.
Laffey JG (2015) ‘Cardiovascular effects of Hypercapnia’ delivered at ESICM Summer Conference on Heart-Lung Interactions’, Dublin, Ireland. Invited Lectures [Details]
(2015) ‘Emerging pharmacologic therapies for ARDS’ delivered at ESICM Summer Conference on Heart-Lung Interactions’.
Laffey JG (2015) ‘Emerging pharmacologic therapies for ARDS’ delivered at ESICM Summer Conference on Heart-Lung Interactions’. Invited Lectures [Details]
(2015) ‘Biomarkers for ARDS’ delivered at ESICM Summer Conference on Heart-Lung Interactions’, Dublin, Ireland.
Laffey JG (2015) ‘Biomarkers for ARDS’ delivered at ESICM Summer Conference on Heart-Lung Interactions’, Dublin, Ireland. Invited Lectures [Details]
(2015) ‘Novel mechanisms of action of MSCs in ARDS’ at third international ARDS conference, Belfast.
Laffey JG (2015) ‘Novel mechanisms of action of MSCs in ARDS’ at third international ARDS conference, Belfast. Invited Lectures [Details]
(2015) ‘Is there any future for stem cells?’ at European Society of Intensive Care Medicine Annual conference, Berlin.
Laffey JG (2015) ‘Is there any future for stem cells?’ at European Society of Intensive Care Medicine Annual conference, Berlin. Invited Lectures [Details]
(2015) ‘The real world: What did we learn from the LUNG-SAFE study’ at European Society of Intensive Care Medicine Annual conference, Berlin.
Laffey JG (2015) ‘The real world: What did we learn from the LUNG-SAFE study’ at European Society of Intensive Care Medicine Annual conference, Berlin. Invited Lectures [Details]
(2015) ‘Cell based therapies for ARDS’, Invited talk at Society of Chinese Bioscientists in America – annual Toronto Chapter Meeting, Toronto, Canada.
Laffey JG (2015) ‘Cell based therapies for ARDS’, Invited talk at Society of Chinese Bioscientists in America – annual Toronto Chapter Meeting, Toronto, Canada. Invited Lectures [Details]
(2015) ‘Gases are Important in ARDS’ at Canadian Critical Care Forum, Toronto.
Laffey JG (2015) ‘Gases are Important in ARDS’ at Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2015) ‘Regeneration and Repair in ARDS – prospects for stem cells’ at Respiratory Failure Masterclass, Canadian Critical Care Forum, Toronto.
Laffey JG (2015) ‘Regeneration and Repair in ARDS – prospects for stem cells’ at Respiratory Failure Masterclass, Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2015) ‘Under recognition of ARDS: Incidence and Consequences’ at European Society of Intensive Care Medicine Annual conference, Berlin.
Laffey JG (2015) ‘Under recognition of ARDS: Incidence and Consequences’ at European Society of Intensive Care Medicine Annual conference, Berlin. Invited Lectures [Details]
(2014) ‘Statins for ARDS: where are we now? Medical Grand Rounds, Galway University Hospitals.
Laffey JG (2014) ‘Statins for ARDS: where are we now? Medical Grand Rounds, Galway University Hospitals. Invited Lectures [Details]
(2014) ‘A clinical trial of MSC therapy for ARDS in Canada: Just do it!’, Invited talk, at ARDS and Critical Illness Cell Therapy Symposium (ACCT) 2014, at the Canadian Critical Care Forum, Toronto.
Laffey JG (2014) ‘A clinical trial of MSC therapy for ARDS in Canada: Just do it!’, Invited talk, at ARDS and Critical Illness Cell Therapy Symposium (ACCT) 2014, at the Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2014) ‘How I use rescue therapies in severe ARDS patients’, Invited participant, round-table session at Severe Acute Respiratory Failure Master-Class, Canadian Critical Care Forum, Toronto.
Laffey JG (2014) ‘How I use rescue therapies in severe ARDS patients’, Invited participant, round-table session at Severe Acute Respiratory Failure Master-Class, Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2014) ‘Conventional mechanical ventilation for ARDS in 2014’, Invited talk at Severe Acute Respiratory Failure Master-Class, Canadian Critical Care Forum, Toronto.
Laffey JG (2014) ‘Conventional mechanical ventilation for ARDS in 2014’, Invited talk at Severe Acute Respiratory Failure Master-Class, Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2014) ‘LUNG SAFE study Results’, Invited talk and Editorial session, at the Canadian Critical Care Forum, Toronto.
Laffey JG (2014) ‘LUNG SAFE study Results’, Invited talk and Editorial session, at the Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2014) Cell based therapies for ARDS: Promise and Pitfalls, International Anesthesia Research Society Annual Scientific Conference, Montreal, Canada.
Laffey JG (2014) Cell based therapies for ARDS: Promise and Pitfalls, International Anesthesia Research Society Annual Scientific Conference, Montreal, Canada. Invited Lectures [Details]
(2014) When more CO2 is less and more – a physiologic approach, University of Toronto Interdisciplinary Dept of Critical Care Annual Residents Day, Toronto, Canada.
Laffey JG (2014) When more CO2 is less and more – a physiologic approach, University of Toronto Interdisciplinary Dept of Critical Care Annual Residents Day, Toronto, Canada. Invited Lectures [Details]
(2014) LUNG SAFE Study: Results from the Northern Hemisphere, European Society of Intensive Care Medicine (ESICM) Annual Conference, Barcelona.
Laffey JG (2014) LUNG SAFE Study: Results from the Northern Hemisphere, European Society of Intensive Care Medicine (ESICM) Annual Conference, Barcelona. Invited Lectures [Details]
(2014) Drug induced ARDS, European Society of Intensive Care Medicine (ESICM) Annual Conference, Barcelona.
Laffey JG (2014) Drug induced ARDS, European Society of Intensive Care Medicine (ESICM) Annual Conference, Barcelona. Invited Lectures [Details]
(2014) ‘Three papers that changed my practice in Drug therapy for ARDS’, European Society of Intensive Care Medicine (ESICM) Annual Conference, Barcelona.
Laffey JG (2014) ‘Three papers that changed my practice in Drug therapy for ARDS’, European Society of Intensive Care Medicine (ESICM) Annual Conference, Barcelona. Invited Lectures [Details]
(2014) ‘ARDS…cell therapies’, Invited talk and Editorial session, at the Canadian Critical Care Forum, Toronto.
Laffey JG (2014) ‘ARDS…cell therapies’, Invited talk and Editorial session, at the Canadian Critical Care Forum, Toronto. Invited Lectures [Details]
(2013) Hypercapnea: An important treatment, not a complication, Saturday Nov 9th, Canadian Critical Care Forum Annual Conference (Residents Day), Toronto.
Laffey JG (2013) Hypercapnea: An important treatment, not a complication, Saturday Nov 9th, Canadian Critical Care Forum Annual Conference (Residents Day), Toronto. Invited Lectures [Details]
(2013) Hypocapnia: Benefit vs. Harm. , Canadian Critical Care Forum Annual Conference, Toronto.
Laffey JG (2013) Hypocapnia: Benefit vs. Harm. , Canadian Critical Care Forum Annual Conference, Toronto. Invited Lectures [Details]
(2013) Mediators in Cardiac Surgery, Canadian Critical Care Forum Annual Conference, Toronto.
Laffey JG (2013) Mediators in Cardiac Surgery, Canadian Critical Care Forum Annual Conference, Toronto. Invited Lectures [Details]
(2013) Stem Cells for ALI/ARDS: Promise and Pitfalls. Canadian Critical Care Forum Annual Conference, Toronto.
Laffey JG (2013) Stem Cells for ALI/ARDS: Promise and Pitfalls. Canadian Critical Care Forum Annual Conference, Toronto. Invited Lectures [Details]
(2013) ‘Cell-based therapy for acute lung injury’, European Society of Intensive Care Medicine Annual Conference, Paris.
Laffey JG (2013) ‘Cell-based therapy for acute lung injury’, European Society of Intensive Care Medicine Annual Conference, Paris. Invited Lectures [Details]
(2013) ‘Drug induced lung injury’, European Society of Intensive Care Medicine Annual Conference, Paris.
Laffey JG (2013) ‘Drug induced lung injury’, European Society of Intensive Care Medicine Annual Conference, Paris. Invited Lectures [Details]
(2013) ‘What I'm learning about ALI in the laboratory’, European Society of Intensive Care Medicine Annual Conference, Paris.
Laffey JG (2013) ‘What I'm learning about ALI in the laboratory’, European Society of Intensive Care Medicine Annual Conference, Paris. Invited Lectures [Details]
(2013) ‘A nightmare: Acute brain injury and concomitant ARDS’, European Society of Intensive Care Medicine Annual Conference, Paris.
Laffey JG (2013) ‘A nightmare: Acute brain injury and concomitant ARDS’, European Society of Intensive Care Medicine Annual Conference, Paris. Invited Lectures [Details]
(2013) ‘Lung repair after ARDS’, European Society of Intensive Care Medicine Annual Conference, Paris.
Laffey JG (2013) ‘Lung repair after ARDS’, European Society of Intensive Care Medicine Annual Conference, Paris. Invited Lectures [Details]
(2013) ‘Wet Lungs – Current Treatment and Future Concepts’, Association of Anaesthetists of Great Britain and Ireland Conference, Dublin.
Laffey JG (2013) ‘Wet Lungs – Current Treatment and Future Concepts’, Association of Anaesthetists of Great Britain and Ireland Conference, Dublin. Invited Lectures [Details]
(2013) ‘Management of severe Hypoxemia, Association of Anaesthetists of Great Britain and Ireland Conference, Dublin.
Laffey JG (2013) ‘Management of severe Hypoxemia, Association of Anaesthetists of Great Britain and Ireland Conference, Dublin. Invited Lectures [Details]
(2013) ‘MSCs for ARDS – ready for Clinical Testing? Medical Grand Rounds, St Vincent’s University Hospital, Dublin.
Laffey JG (2013) ‘MSCs for ARDS – ready for Clinical Testing? Medical Grand Rounds, St Vincent’s University Hospital, Dublin. Invited Lectures [Details]
(2013) ‘Airway Management in the Critically Ill: Can we do Better?’ Invited presentation at the at XIIth Annual conference on Mechanical Ventilation, Rio de Janeiro, Brazil.
Laffey JG (2013) ‘Airway Management in the Critically Ill: Can we do Better?’ Invited presentation at the at XIIth Annual conference on Mechanical Ventilation, Rio de Janeiro, Brazil. Invited Lectures [Details]
(2013) ‘Hypercapnic Acidosis: Role in Ventilation Induced Lung Injury’, XIIth Annual conference on Mechanical Ventilation, Rio de Janeiro, Brazil.
Laffey JG (2013) ‘Hypercapnic Acidosis: Role in Ventilation Induced Lung Injury’, XIIth Annual conference on Mechanical Ventilation, Rio de Janeiro, Brazil. Invited Lectures [Details]
(2013) ‘Stem cell therapy for ARDS: a dream becoming true? SMART Conference Milan.
Laffey JG (2013) ‘Stem cell therapy for ARDS: a dream becoming true? SMART Conference Milan. Invited Lectures [Details]
(2013) ‘Hypercapnia in ARDS: should we permit, avoid or remove? SMART Conference Milan.
Laffey JG (2013) ‘Hypercapnia in ARDS: should we permit, avoid or remove? SMART Conference Milan. Invited Lectures [Details]
(2013) MSCs for ARDS: Potential and Pitfalls. Anesthesia Grant Rounds, Beth Israel hospital, Harvard, Boston.
Laffey JG (2013) MSCs for ARDS: Potential and Pitfalls. Anesthesia Grant Rounds, Beth Israel hospital, Harvard, Boston. Invited Lectures [Details]
(2013) ‘Eclampsia and HELLP’, International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2013) ‘Eclampsia and HELLP’, International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2013) ‘Novel laryngoscopes?’ International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2013) ‘Novel laryngoscopes?’ International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2013) ‘Basics of respiratory physiology’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2013) ‘Basics of respiratory physiology’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2013) ‘Hypercapnia: Benefit or harm?’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2013) ‘Hypercapnia: Benefit or harm?’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2013) ‘Role of hypercapnia in protective lung ventilation strategies’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2013) ‘Role of hypercapnia in protective lung ventilation strategies’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2013) ‘Gene stem cell therapies’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2013) ‘Gene stem cell therapies’. International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2012) ‘Hypocapnia and the Injured Brain: More Harm than Benefit’, Toronto Critical Care Medicine Symposium, Toronto.
Laffey JG (2012) ‘Hypocapnia and the Injured Brain: More Harm than Benefit’, Toronto Critical Care Medicine Symposium, Toronto. Invited Lectures [Details]
(2012) Editorial commentary on ‘Prone position in ARDS – A randomized Clinical Trial’, Toronto Critical Care Medicine Symposium, Toronto.
Laffey JG (2012) Editorial commentary on ‘Prone position in ARDS – A randomized Clinical Trial’, Toronto Critical Care Medicine Symposium, Toronto. Invited Lectures [Details]
(2012) ‘Gene and Stem Cell therapies for ARDS – hope or hype’ presented at Scottish Intensive Care Society annual Scientific conference in St Andrews, Scotland.
Laffey JG (2012) ‘Gene and Stem Cell therapies for ARDS – hope or hype’ presented at Scottish Intensive Care Society annual Scientific conference in St Andrews, Scotland. Invited Lectures [Details]
(2012) ‘Effects of Hypercapnia in injury, inflammation and repair’, presented at Scottish Intensive Care Society annual Scientific conference in St Andrews, Scotland.
Laffey JG (2012) ‘Effects of Hypercapnia in injury, inflammation and repair’, presented at Scottish Intensive Care Society annual Scientific conference in St Andrews, Scotland. Invited Lectures [Details]
(2012) Hypercapnia in ARDS – balancing risks and benefits’, presented at NVIC (Nederlandse Intensivistendagen) 2012 Intensive Care Society annual Scientific conference in Ede, The Netherlands.
Laffey JG (2012) Hypercapnia in ARDS – balancing risks and benefits’, presented at NVIC (Nederlandse Intensivistendagen) 2012 Intensive Care Society annual Scientific conference in Ede, The Netherlands. Invited Lectures [Details]
(2012) ‘Stem Cells for ARDS’, 33rd International SMART Conference, Milan, Italy.
Laffey JG (2012) ‘Stem Cells for ARDS’, 33rd International SMART Conference, Milan, Italy. Invited Lectures [Details]
(2012) ‘Mesenchymal Stem cells for ARDS: Potential and Pitfalls’ at USCF ARDS Symposium, San Francisco.
Laffey JG (2012) ‘Mesenchymal Stem cells for ARDS: Potential and Pitfalls’ at USCF ARDS Symposium, San Francisco. Invited Lectures [Details]
(2012) ‘Research Methods – How it should be’, Euroanaesthesia Conference, Paris, France.
Laffey JG (2012) ‘Research Methods – How it should be’, Euroanaesthesia Conference, Paris, France. Invited Lectures [Details]
(2012) ‘Mesenchymal Stem cells for ARDS: Potential and Pitfalls’ at St Michael’s Hospital, MGR, St Michael’s Hospital, Toronto.
Laffey JG (2012) ‘Mesenchymal Stem cells for ARDS: Potential and Pitfalls’ at St Michael’s Hospital, MGR, St Michael’s Hospital, Toronto. Invited Lectures [Details]
(2012) ‘Mesenchymal Stem cells for Ventilation induced Lung Injury: From bench to Bedside’, International Symposium in Acute Lung Injury, London.
Laffey JG (2012) ‘Mesenchymal Stem cells for Ventilation induced Lung Injury: From bench to Bedside’, International Symposium in Acute Lung Injury, London. Invited Lectures [Details]
(2012) ‘Hypercapnia. Friend or foe’, European Society of Intensive Care Medicine Annual Conference, Lisbon.
Laffey JG (2012) ‘Hypercapnia. Friend or foe’, European Society of Intensive Care Medicine Annual Conference, Lisbon. Invited Lectures [Details]
(2012) ‘Stem cells for ALI/ARDS’, European Society of Intensive Care Medicine Annual Conference, Lisbon.
Laffey JG (2012) ‘Stem cells for ALI/ARDS’, European Society of Intensive Care Medicine Annual Conference, Lisbon. Invited Lectures [Details]
(2012) ‘Stem cells to speed recovery from ARDS’, Toronto Critical Care Medicine Symposium, Toronto.
Laffey JG (2012) ‘Stem cells to speed recovery from ARDS’, Toronto Critical Care Medicine Symposium, Toronto. Invited Lectures [Details]
(2012) ‘Buffering a permissive Hypercapnia – the Evidence’, Toronto Critical Care Medicine Symposium, Toronto.
Laffey JG (2012) ‘Buffering a permissive Hypercapnia – the Evidence’, Toronto Critical Care Medicine Symposium, Toronto. Invited Lectures [Details]
(2012) ‘Mesenchymal Stem Cells for ALI/ARDS: Promise and Pitfalls’, Toronto Critical Care Medicine Symposium, Toronto.
Laffey JG (2012) ‘Mesenchymal Stem Cells for ALI/ARDS: Promise and Pitfalls’, Toronto Critical Care Medicine Symposium, Toronto. Invited Lectures [Details]
(2011) ‘The critically ill pregnant patient’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2011) ‘The critically ill pregnant patient’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2011) ‘Hypercapnia – effects in septic versus non-septic ALI/ARDS’, presented at American Thoracic society Annual Conference, Denver.
Laffey JG (2011) ‘Hypercapnia – effects in septic versus non-septic ALI/ARDS’, presented at American Thoracic society Annual Conference, Denver. Invited Lectures [Details]
(2011) ‘What is Stem Cell Therapy?’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2011) ‘What is Stem Cell Therapy?’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2011) ‘Respiratory Physiology for Clinicians’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2011) ‘Respiratory Physiology for Clinicians’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2011) ‘Hypercapnia may be beneficial in inflammation and ARDS’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM).
Laffey JG (2011) ‘Hypercapnia may be beneficial in inflammation and ARDS’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM). Invited Lectures [Details]
(2011) ‘Hypercapnia may be beneficial for the brain’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2011) ‘Hypercapnia may be beneficial for the brain’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2011) ‘Recent Research tells us how to ventilate normal lungs’, presented at Winterlude Perioperative Medicine Conference, Ottawa, Canada.
Laffey JG (2011) ‘Recent Research tells us how to ventilate normal lungs’, presented at Winterlude Perioperative Medicine Conference, Ottawa, Canada. Invited Lectures [Details]
(2011) ‘Gene therapies for Multi-organ Failure’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2011) ‘Gene therapies for Multi-organ Failure’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2011) ‘Do we need novel laryngoscopes?’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels.
Laffey JG (2011) ‘Do we need novel laryngoscopes?’, presented at International Symposium on Intensive Care and Emergency Medicine (ISICEM) Conference, Brussels. Invited Lectures [Details]
(2010) ‘Stem Cell therapies for ALI/ARDS’ at the Tissue Engineering and Regenerative Medicine (TERMIS) 2010 European Conference, NUI Galway.
Laffey JG (2010) ‘Stem Cell therapies for ALI/ARDS’ at the Tissue Engineering and Regenerative Medicine (TERMIS) 2010 European Conference, NUI Galway. Invited Lectures [Details]
(2010) ‘Injury and Repair following ALI: From Hypercapnia to Stem Cells’, presented at Acute Lung Injury Investigators Conference, Paris.
Laffey JG (2010) ‘Injury and Repair following ALI: From Hypercapnia to Stem Cells’, presented at Acute Lung Injury Investigators Conference, Paris. Invited Lectures [Details]
(2010) ‘Hypocapnia in Acute Brain Injury – evidence for Harm’ presented at 10th Perioperative Controversies International Conference, Dingle, Ireland.
Laffey JG (2010) ‘Hypocapnia in Acute Brain Injury – evidence for Harm’ presented at 10th Perioperative Controversies International Conference, Dingle, Ireland. Invited Lectures [Details]
(2010) ‘Hypercapnic Acidosis – bad in Sepsis induced ARDS?’ presented at 10th Perioperative Controversies International Conference, Dingle, Ireland.
Laffey JG (2010) ‘Hypercapnic Acidosis – bad in Sepsis induced ARDS?’ presented at 10th Perioperative Controversies International Conference, Dingle, Ireland. Invited Lectures [Details]
(2010) ‘Lung Protective Strategies in Sepsis’ at the 4th Yale University/ Royal College of Surgeons in Ireland 4th joint Anaesthesia and Critical Care Symposium, Killarney, Ireland.
Laffey JG (2010) ‘Lung Protective Strategies in Sepsis’ at the 4th Yale University/ Royal College of Surgeons in Ireland 4th joint Anaesthesia and Critical Care Symposium, Killarney, Ireland. Invited Lectures [Details]
(2010) Hypercapnic Acidosis – bad in Sepsis induced ARDS?’ presented at United Kingdom and Ireland ALI Investigator Meeting, London.
Laffey JG (2010) Hypercapnic Acidosis – bad in Sepsis induced ARDS?’ presented at United Kingdom and Ireland ALI Investigator Meeting, London. Invited Lectures [Details]
(2008) Special Critical Populations: The Pregnant Patient, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels.
Laffey JG (2008) Special Critical Populations: The Pregnant Patient, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels. Invited Lectures [Details]
(2008) ‘New therapies for ARDS: Pushing the Boundaries’ Keynote speaker, Drager Medal Lecture, Annual Conference of Association of Anaesthetists of Great Britain and Ireland, Torquay, UK.
Laffey JG (2008) ‘New therapies for ARDS: Pushing the Boundaries’ Keynote speaker, Drager Medal Lecture, Annual Conference of Association of Anaesthetists of Great Britain and Ireland, Torquay, UK. Invited Lectures [Details]
(2008) ‘New therapies for ARDS: Pushing the Boundaries’ presented at 8th Perioperative Controversies International Conference, Dingle, Ireland.
Laffey JG (2008) ‘New therapies for ARDS: Pushing the Boundaries’ presented at 8th Perioperative Controversies International Conference, Dingle, Ireland. Invited Lectures [Details]
(2008) Buffering a Hypercapnic Acidosis, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels.
Laffey JG (2008) Buffering a Hypercapnic Acidosis, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels. Invited Lectures [Details]
(2008) Lung Physiology: Gas Exchange, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels.
Laffey JG (2008) Lung Physiology: Gas Exchange, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels. Invited Lectures [Details]
(2008) Gene and Stem Cell Therapies for ARDS, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels.
Laffey JG (2008) Gene and Stem Cell Therapies for ARDS, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels. Invited Lectures [Details]
(2008) The Inflammatory Response to Cardiac Surgery, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels.
Laffey JG (2008) The Inflammatory Response to Cardiac Surgery, 28th International Symposium on Intensive Care and Emergency Medicine, Brussels. Invited Lectures [Details]
(2007) ‘Permissive Hypercapnia: Role in Protective Lung ventilations strategies’, Grand Rounds, University College London Hospital.
Laffey JG (2007) ‘Permissive Hypercapnia: Role in Protective Lung ventilations strategies’, Grand Rounds, University College London Hospital. Invited Lectures [Details]
(2007) ‘Hypercapnia and Protective Lung Ventilation – Friend or Foe?’ presented at 7th Perioperative Controversies International Conference, Dingle 2007 Conference.
Laffey JG (2007) ‘Hypercapnia and Protective Lung Ventilation – Friend or Foe?’ presented at 7th Perioperative Controversies International Conference, Dingle 2007 Conference. Invited Lectures [Details]
(2007) ‘Ethylene Glycol Poisoning, New Antidotes and Management in 2007’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India.
Laffey JG (2007) ‘Ethylene Glycol Poisoning, New Antidotes and Management in 2007’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India. Invited Lectures [Details]
(2007) ‘The Critically ill Obstetric Patient’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India.
Laffey JG (2007) ‘The Critically ill Obstetric Patient’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India. Invited Lectures [Details]
(2007) ‘Mechanical Ventilation – Shake Rattle and Roll 2007’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India.
Laffey JG (2007) ‘Mechanical Ventilation – Shake Rattle and Roll 2007’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India. Invited Lectures [Details]
(2007) ‘Toxic Alcohol Poisoning – State of the Art’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India.
December 7th 2007 (2007) ‘Toxic Alcohol Poisoning – State of the Art’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India. Invited Lectures [Details]
(2007) ‘Mechanical Ventilation – the Basics’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India.
Laffey JG (2007) ‘Mechanical Ventilation – the Basics’, presented at Asia Pacific Critical Care Conference 2007, New Delhi, India. Invited Lectures [Details]

Invited papers

  Year Publication
Permissive Hypercapnia at the Intensive Care Society UK, Annual State of the Art Conference London, UK.
J.G. Laffey Permissive Hypercapnia at the Intensive Care Society UK, Annual State of the Art Conference London, UK. Invited papers [Details]
(2006) ‘Buffering Hypercapnic Acidosis’ delivered at European Society of Intensive Care Medicine Annual conference Barcelona, Spain.
J.G. Laffey (2006) ‘Buffering Hypercapnic Acidosis’ delivered at European Society of Intensive Care Medicine Annual conference Barcelona, Spain. Invited papers [Details]
(2006) Ethylene Glycol Intoxication. ‘The critically ill Obstetric Patient’ delivered at European Society of Intensive Care Medicine Annual conference Barcelona, Spain.
J.G. Laffey (2006) Ethylene Glycol Intoxication. ‘The critically ill Obstetric Patient’ delivered at European Society of Intensive Care Medicine Annual conference Barcelona, Spain. Invited papers [Details]
(2006) ‘Advances in Mechanical Ventilation’, delivered at Association of Critical Care Nurses Annual Meeting, May 27th 2006.
J.G. Laffey (2006) ‘Advances in Mechanical Ventilation’, delivered at Association of Critical Care Nurses Annual Meeting, May 27th 2006. Galway, Ireland: Invited papers [Details]
(2006) Caring for the Critically ill Mother. 'Obstetric Critical Care' Dingle 2006 Conference Dingle, Ireland.
J.G. Laffey (2006) Caring for the Critically ill Mother. 'Obstetric Critical Care' Dingle 2006 Conference Dingle, Ireland. Invited papers [Details]
(2006) Low Tidal volume Ventilation – with or without permissive hypercapnia?. 'Role of hypercapnia in protective lung ventilatory strategies' at ICSI/SICS Meeting Dunblane, Scotland.
J.G. Laffey (2006) Low Tidal volume Ventilation – with or without permissive hypercapnia?. 'Role of hypercapnia in protective lung ventilatory strategies' at ICSI/SICS Meeting Dunblane, Scotland. Invited papers [Details]
(2006) ‘Ethylene Glycol Intoxication' delivered at European Society of Intensive Care Medicine Annual conference.
J.G. Laffey (2006) ‘Ethylene Glycol Intoxication' delivered at European Society of Intensive Care Medicine Annual conference. Barcelona, Spain: Invited papers [Details]
(2006) The critically ill child with Meningococcemia. Critical Care Nursing Conference .
J.G. Laffey (2006) The critically ill child with Meningococcemia. Critical Care Nursing Conference . Galway, Ireland: Invited papers [Details]
(2006) ‘The inflammatory response to Surgery’ delivered at Western anaesthesia Symposium.
J.G. Laffey (2006) ‘The inflammatory response to Surgery’ delivered at Western anaesthesia Symposium. Invited papers [Details]
(2006) ‘Meningococcemia’ delivered to Critical Care Nursing Conference .
J.G. Laffey (2006) ‘Meningococcemia’ delivered to Critical Care Nursing Conference . Galway, Ireland: Invited papers [Details]
(2005) Mechanical Ventilation – From Bench to Bedside' at the Dingle 2005 Annual Symposium .
J.G. Laffey (2005) Mechanical Ventilation – From Bench to Bedside' at the Dingle 2005 Annual Symposium . Dingle, Ireland: Invited papers [Details]
(2004) The inflammatory response to Cardiac Surgery, Annual Winter Anaesthesia Symposium.
J.G. Laffey (2004) The inflammatory response to Cardiac Surgery, Annual Winter Anaesthesia Symposium. University of Leuven, Belgium: Invited papers [Details]
(2003) Low Tidal volume Ventilation – with or without permissive hypercapnia? .
J.G. Laffey (2003) Low Tidal volume Ventilation – with or without permissive hypercapnia? . Berlin, Germany: Invited papers [Details]
(2003) Buffering that Acidosis – treating the patient or the physician?.
J.G. Laffey (2003) Buffering that Acidosis – treating the patient or the physician?. Galway, Ireland: Invited papers [Details]
(2003) Perioperative ACE Inhibitors and Patient Outcome .
J.G. Laffey (2003) Perioperative ACE Inhibitors and Patient Outcome . Dublin, Ireland: Invited papers [Details]
(2003) Maternal Brain Death in Ireland – Medical, Legal and Ethical issues. Submission to Roundtable Discussion Forum, Winter Scientific Meeting.
J.G. Laffey (2003) Maternal Brain Death in Ireland – Medical, Legal and Ethical issues. Submission to Roundtable Discussion Forum, Winter Scientific Meeting. Intensive Care Society of Ireland Dublin, Ireland: Invited papers [Details]
(2001) Hypercapnia – from ‘Permissive’ to Therapeutic’. Anaesthesia Grand Rounds.
J.G. Laffey (2001) Hypercapnia – from ‘Permissive’ to Therapeutic’. Anaesthesia Grand Rounds. Adelaide Meath and National Children?s Hospital: Invited papers [Details]
(2001) Therapeutic Hypercapnia – current insights, future prospects.Research Grand Rounds.
J.G. Laffey (2001) Therapeutic Hypercapnia – current insights, future prospects.Research Grand Rounds. University College Hospital Galway, Ireland: Invited papers [Details]
(2001) Carbon dioxide and Acute Organ Injury. Respiratory Research Rounds.
J.G. Laffey (2001) Carbon dioxide and Acute Organ Injury. Respiratory Research Rounds. St. Vincent?s University Hospital Dublin, Ireland: Invited papers [Details]
(2000) Carbon Dioxide and the critically ill – too little of a good thing. Critical Care Grand Rounds, University of Toronto, Hospital for Sick Children.
J.G. Laffey (2000) Carbon Dioxide and the critically ill – too little of a good thing. Critical Care Grand Rounds, University of Toronto, Hospital for Sick Children. Invited papers [Details]
(1998) The Post Anaesthesia Care Unit - the anaesthetists’ perspective, National symposium on Post-Anaesthesia Care, Mater Hospital Dublin, Ireland.
J.G. Laffey (1998) The Post Anaesthesia Care Unit - the anaesthetists’ perspective, National symposium on Post-Anaesthesia Care, Mater Hospital Dublin, Ireland. Invited papers [Details]

Letter

  Year Publication
(2016) The LUNG SAFE Study: a presentation of the prevalence of ARDS according to the Berlin definition! Critical Care.
Laffey JG, Bellani G, Pham T, Fan E, et al on behalf of the LUNG SAFE Investigators (2016) The LUNG SAFE Study: a presentation of the prevalence of ARDS according to the Berlin definition! Critical Care. Letter [Details]
(2011) Placebo blocks in local anaesthesia studies: the need for balance.
Laffey, J (2011) Placebo blocks in local anaesthesia studies: the need for balance. Letter [DOI] [Details]
(2011) Hypocapnia and the injured brain: Evidence for harm.
Curley, G,Kavanagh, BP,Laffey, JG (2011) Hypocapnia and the injured brain: Evidence for harm. Letter [DOI] [Details]
(2011) Selective digestive decontamination reduces bacteremia following eradication of gut overgrowth reply.
Quigley, EM,Laffey, JG (2011) Selective digestive decontamination reduces bacteremia following eradication of gut overgrowth reply. Letter [DOI] [Details]
(2010) The learning curve for videolaryngoscopy Reply.
McElwain, J,Laffey, JG (2010) The learning curve for videolaryngoscopy Reply. Letter [DOI] [Details]
(2010) Comparison of the C-MAC (R) videolaryngoscope with the Macintosh, Glidescope (R) and Airtraq (R) laryngoscopes in easy and difficult laryngoscopy scenarios in manikins reply.
McElwain, J,Laffey, JG (2010) Comparison of the C-MAC (R) videolaryngoscope with the Macintosh, Glidescope (R) and Airtraq (R) laryngoscopes in easy and difficult laryngoscopy scenarios in manikins reply. Letter [DOI] [Details]
(2010) Difficult tracheal intubation. Br J Anaesth.
(4) McElwain J, Malik MA, Laffey JG (2010) Difficult tracheal intubation. Br J Anaesth. Letter [Details]
(2008) Subcostal transversus abdominis plane block under ultrasound guidance - Reply.
Laffey, JG,McDonnell, JG (2008) Subcostal transversus abdominis plane block under ultrasound guidance - Reply. Letter [DOI] [Details]
(2007) Meralgia Paraesthetica. Irish Medical Journal.
Lynch T, Kinirons B, Laffey J. (2007) Meralgia Paraesthetica. Irish Medical Journal. Letter [Details]
(2007) The transversus abdominis plane block - Response.
McDonnell, JG,Laffey, JG (2007) The transversus abdominis plane block - Response. Letter [DOI] [Details]
(2007) Transversus abdominis plane block - Response.
McDonnell, JG,Laffey, JG (2007) Transversus abdominis plane block - Response. Letter [DOI] [Details]
(2006) Hypertension in Pregnancy?. Anesthesiology.
Lynch T, Laffey J. (2006) Hypertension in Pregnancy?. Anesthesiology. Letter [Details]
(2006) Sildenafil for pulmonary hypertension in pregnancy?.
Lynch, TD,Laffey, JG (2006) Sildenafil for pulmonary hypertension in pregnancy?. Letter [Details]
(2004) CO2 and lung mechanical or gas exchange function. Critical Care Medicine.
Laffey JG, Kavanagh BP (2004) CO2 and lung mechanical or gas exchange function. Critical Care Medicine. Letter [Details]
(2002) Hypocapnia - Reply.
Laffey, J,Kavanagh, BP (2002) Hypocapnia - Reply. Letter [Details]
(2002) Acid base disorders in the critically ill. Anaesthesia.
Laffey JG (2002) Acid base disorders in the critically ill. Anaesthesia. Letter [Details]
(2001) Low dose spinal morphine for postoperative analgesia following knee arthroplasty. British Journal of Anaesthesia.
Laffey JG, Flynn N (2001) Low dose spinal morphine for postoperative analgesia following knee arthroplasty. British Journal of Anaesthesia. Letter [Details]
(2001) Protective effects of acidosis. Anaesthesia.
Laffey JG, Bellani G, Pham T, Fan E, et al on behalf of the LUNG SAFE Investigators2001 (2001) Protective effects of acidosis. Anaesthesia. Letter [Details]
(2001) Low-dose spinal morphine for postoperative analgesia following knee arthroplasty.
Laffey, JG,Flynn, N (2001) Low-dose spinal morphine for postoperative analgesia following knee arthroplasty. Letter [Details]
(2001) Patient compliance with preoperative day case instructions Anaesthesia.
Laffey JG, Boylan JF (2001) Patient compliance with preoperative day case instructions Anaesthesia. Letter [Details]
(2000) Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury. The New England Journal of Medicine.
Curley G, Kavanagh BP, Laffey JG (2000) Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury. The New England Journal of Medicine. Letter [Details]

Meeting

  Year Publication
(2013) In vivo inhibition of pulmonary nuclear factor kappa-B attenuates ventilator-induced lung injury in the rat.
Hayes, MB,Curley, GF,Devaney, J,O'Toole, DP,Laffey, JG (2013) In vivo inhibition of pulmonary nuclear factor kappa-B attenuates ventilator-induced lung injury in the rat. Meeting [Details]
(2013) Human mesenchymal stem cells enhance repair after ventilator-induced lung injury.
Hayes, M,Curley, G,Ansari, B,O'Toole, D,Laffey, J (2013) Human mesenchymal stem cells enhance repair after ventilator-induced lung injury. Meeting [Details]
(2012) Carbon dioxide (CO2) sensing at the axis of immunity and inflammation.
Oliver, KM,Lenihan, CR,Bruning, U,Cheong, A,Laffey, JG,McLoughlin, P,Fitzpatrick, SF,Scholz, CC,Slattery, C,Leonard, MO,Taylor, CT,Cummins, EP (2012) Carbon dioxide (CO2) sensing at the axis of immunity and inflammation. Meeting [Details]
(2010) Hypercapnic Acidosis Impairs Inflammatory Signalling Via Inhibition Of Multiple Points Of The NF-kappa B Pathway.
O'Toole, D,Masterson, C,Leo, A,Contreras, M,Hassett, P,Laffey, J (2010) Hypercapnic Acidosis Impairs Inflammatory Signalling Via Inhibition Of Multiple Points Of The NF-kappa B Pathway. Meeting [Details]
(2010) Hypercapnic Acidosis Attenuates Moderate And Severe Ventilator Induced Lung Injury By An NF-kB Dependent Mechanism.
Contreras, M,O'Toole, D,Higgins, B,Ansari, BM,Curley, GF,Masterson, C,Laffey, J (2010) Hypercapnic Acidosis Attenuates Moderate And Severe Ventilator Induced Lung Injury By An NF-kB Dependent Mechanism. Meeting [Details]
(2010) Time Course Of Lung Injury, Inflammation, Repair And Fibrosis Following Ventilator Induced Lung Injury.
Curley, GF,Contreras, M,Higgins, B,O'Toole, D,O'Kane, C,Laffey, J (2010) Time Course Of Lung Injury, Inflammation, Repair And Fibrosis Following Ventilator Induced Lung Injury. Meeting [Details]
(2010) MESENCHYMAL STEM CELLS ENHANCE REPAIR FOLLOWING VENTILATOR INDUCED LUNG INJURY.
Curley, GF,Contreras, M,Ansari, B,Masterson, C,McHale, P,Devaney, J,Higgins, BD,O'Toole, D,Laffey, JG (2010) MESENCHYMAL STEM CELLS ENHANCE REPAIR FOLLOWING VENTILATOR INDUCED LUNG INJURY. Meeting [Details]
(2010) HYPERCAPNIC ACIDOSIS REDUCES STRETCH-INDUCED INFLAMMATION BY AN NF-KAPPA B-DEPENDENT MECHANISM.
Ansari, BM,Contreras, M,O'Toole, D,Laffey, J (2010) HYPERCAPNIC ACIDOSIS REDUCES STRETCH-INDUCED INFLAMMATION BY AN NF-KAPPA B-DEPENDENT MECHANISM. Meeting [Details]
(2009) Molecular Effects of Hypercapnic Acidosis on the NF-kappa B Intracellular Signalling Pathway.
O'Toole, DP,Hassett, PD,Leo, AM,Higgins, BD,Laffey, JG (2009) Molecular Effects of Hypercapnic Acidosis on the NF-kappa B Intracellular Signalling Pathway. Meeting [Details]
(2009) Prolonged Hypercapnia Reduces the Severity of Acute Lung Injury in Chronic Polymicrobial Sepsis.
Contreras, M,Costello, J,Higgins, B,O'Tool, D,Hassett, P,Laffey, JG (2009) Prolonged Hypercapnia Reduces the Severity of Acute Lung Injury in Chronic Polymicrobial Sepsis. Meeting [Details]
(2009) Hypercapnic Acidosis Inhibits TNF alpha Induced Wound Healing in a Lung Cell Culture Model.
O'Toole, D,Hassett, P,Leo, A,Higgins, BD,Laffey, JG (2009) Hypercapnic Acidosis Inhibits TNF alpha Induced Wound Healing in a Lung Cell Culture Model. Meeting [Details]
(2008) Aerosol delivery of AAV5-gfp to the rodent lung.
Mac Loughlin, R,Higgins, B,Laffey, J,O'Brien, T (2008) Aerosol delivery of AAV5-gfp to the rodent lung. Meeting [Details]

Reviews

  Year Publication
(2021) Unlocking the surge in demand for personal and protective equipment (PPE) and improvised face coverings arising from coronavirus disease (COVID-19) pandemic - Implications for efficacy, re-use and sustainable waste management.
Rowan, NJ;Laffey, JG (2021) Unlocking the surge in demand for personal and protective equipment (PPE) and improvised face coverings arising from coronavirus disease (COVID-19) pandemic - Implications for efficacy, re-use and sustainable waste management. AMSTERDAM: ELSEVIER Reviews [DOI] [Details]
(2020) Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence.
van Haren, FMP;Page, C;Laffey, JG;Artigas, A;Camprubi-Rimblas, M;Nunes, Q;Smith, R;Shute, J;Carroll, M;Tree, J;Carroll, M;Singh, D;Wilkinson, T;Dixon, B (2020) Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence. LONDON: BMC Reviews [DOI] [Details]
(2020) Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis.
Carla, A;Pereira, B;Boukail, H;Audard, J;Pinol-Domenech, N;De Carvalho, M;Blondonnet, R;Zhai, RY;Morand, D;Lambert, C;Sapin, V;Ware, LB;Calfee, CS;Bastarache, JA;Laffey, JG;Juffermans, NP;Bos, LD;Artigas, A;Rocco, PRM;Matthay, MA;McAuley, DF;Constantin, JM;Jabaudon, M (2020) Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis. LONDON: BMC Reviews [DOI] [Details]
(2019) Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns.
Masterson, CH;Curley, GF;Laffey, JG (2019) Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns. LONDON: SPRINGEROPEN Reviews [DOI] [Details]
(2002) Isoprostanes - markers of ischaemia reperfusion injury.
Sakamoto, H,Corcoran, TB,Laffey, JG,Shorten, GD (2002) Isoprostanes - markers of ischaemia reperfusion injury. Reviews [Details]
(2002) The systemic inflammatory response to cardiac surgery - Implications for the anesthesiologist.
Laffey, JG;Boylan, JF;Cheng, DCH (2002) The systemic inflammatory response to cardiac surgery - Implications for the anesthesiologist. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [Details]
(2004) Permissive hypercapnia - role in protective lung ventilatory strategies.
Laffey, JG;O'Croinin, D;McLoughlin, P;Kavanagh, BP (2004) Permissive hypercapnia - role in protective lung ventilatory strategies. NEW YORK: SPRINGER Reviews [DOI] [Details]
(2005) Permissive hypercapnia: role in protective lung ventilatory strategies.
Ni Chonghaile, M;Higgins, B;Laffey, JG (2005) Permissive hypercapnia: role in protective lung ventilatory strategies. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [Details]
(2005) Maternal brain death and somatic support.
Farragher, RA;Laffey, JG (2005) Maternal brain death and somatic support. TOTOWA: HUMANA PRESS INC Reviews [DOI] [Details]
(2005) Maternal brain death - an Irish perspective.
Farragher, R;Marsh, B;Laffey, JG (2005) Maternal brain death - an Irish perspective. LONDON: SPRINGER LONDON LTD Reviews [Details]
(2005) Bench-to-bedside review: Permissive hypercapnia.
O'Croinin, D;Chonghaile, MN;Higgins, B;Laffey, JG (2005) Bench-to-bedside review: Permissive hypercapnia. LONDON: BMC Reviews [DOI] [Details]
(2010) Hypocapnia and the injured brain: More harm than benefit.
Curley, G;Kavanagh, BP;Laffey, JG (2010) Hypocapnia and the injured brain: More harm than benefit. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [DOI] [Details]
(2010) Bench-to-bedside review: Carbon dioxide.
Curley, G;Laffey, JG;Kavanagh, BP (2010) Bench-to-bedside review: Carbon dioxide. LONDON: BMC Reviews [DOI] [Details]
(2010) Hypercapnia and Acidosis in Sepsis A Double-edged Sword?.
Curley, G;Contreras, M;Nichol, AD;Higgins, BD;Laffey, JG (2010) Hypercapnia and Acidosis in Sepsis A Double-edged Sword?. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [Details]
(2011) Clinical Review: Gene-based therapies for ALI/ARDS: where are we now?.
Devaney, J;Contreras, M;Laffey, JG (2011) Clinical Review: Gene-based therapies for ALI/ARDS: where are we now?. LONDON: BIOMED CENTRAL LTD Reviews [DOI] [Details]
(2011) Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS?.
Curley, G,Hayes, M,Laffey, JG (2011) Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS?. Reviews [DOI] [Details]
(2011) Clinical review: Special populations - critical illness and pregnancy.
Neligan, PJ;Laffey, JG (2011) Clinical review: Special populations - critical illness and pregnancy. LONDON: BIOMED CENTRAL LTD Reviews [DOI] [Details]
(2012) Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype?.
Hayes, M;Curley, G;Ansari, B;Laffey, JG (2012) Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype?. LONDON: BMC Reviews [DOI] [Details]
(2015) Mesenchymal stromal cell therapies: potential and pitfalls for ARDS.
Masterson, C;Jerkic, M;Curley, GF;Laffey, JG (2015) Mesenchymal stromal cell therapies: potential and pitfalls for ARDS. TURIN: EDIZIONI MINERVA MEDICA Reviews [Details]
(2015) Mesenchymal stromal cell therapies: potential and pitfalls for ARDS.
Masterson, C,Jerkic, M,Curley, GF,Laffey, JG (2015) Mesenchymal stromal cell therapies: potential and pitfalls for ARDS. Reviews [Details]
(2016) Stem cell therapy for acute respiratory distress syndrome: a promising future?.
Horie, S,Masterson, C,Devaney, J,Laffey, JG (2016) Stem cell therapy for acute respiratory distress syndrome: a promising future?. Reviews [DOI] [Details]
(2017) Stem Cell-based Therapies for Sepsis.
Keane, C;Jerkic, M;Laffey, JG (2017) Stem Cell-based Therapies for Sepsis. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [DOI] [Details]
(2017) Noninvasive mechanical ventilation in early acute respiratory distress syndrome.
Grassi, A;Foti, G;Laffey, JG;Bellani, G (2017) Noninvasive mechanical ventilation in early acute respiratory distress syndrome. KRAKOW: MEDYCYNA PRAKTYCZNA Reviews [DOI] [Details]
(2017) Suprascapular and Interscalene Nerve Block for Shoulder Surgery: A Systematic Review and Meta-analysis.
Hussain, N;Goldar, G;Ragina, N;Banfield, L;Laffey, JG;Abdallah, FW (2017) Suprascapular and Interscalene Nerve Block for Shoulder Surgery: A Systematic Review and Meta-analysis. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [DOI] [Details]
(2018) Cell therapy in acute respiratory distress syndrome.
Horie, S;Gonzalez, HE;Laffey, JG;Masterson, CH (2018) Cell therapy in acute respiratory distress syndrome. SHATIN: AME PUBL CO Reviews [DOI] [Details]
(2018) Lessons to learn from epidemiologic studies in ARDS.
McNicholas, BA;Rooney, GM;Laffey, JG (2018) Lessons to learn from epidemiologic studies in ARDS. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [DOI] [Details]
(2018) A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk.
McDonnell, MJ;O'Toole, D;Ward, C;Pearson, JP;Lordan, JL;De Soyza, A;Loebinger, M;Chalmers, JD;Laffey, JG;Rutherford, RM (2018) A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk. LONDON: W B SAUNDERS CO LTD Reviews [DOI] [Details]
(2012) Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype?.
Hayes, M,Curley, G,Ansari, B,Laffey, JG (2012) Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype?. Reviews [DOI] [Details]
(2011) Clinical review: Special populations - critical illness and pregnancy.
Neligan, PJ,Laffey, JG (2011) Clinical review: Special populations - critical illness and pregnancy. Reviews [DOI] [Details]
(2011) Clinical Review: Gene-based therapies for ALI/ARDS: where are we now?.
Devaney, J,Contreras, M,Laffey, JG (2011) Clinical Review: Gene-based therapies for ALI/ARDS: where are we now?. Reviews [DOI] [Details]
(2010) Bench-to-bedside review: Carbon dioxide.
Curley, G,Laffey, JG,Kavanagh, BP (2010) Bench-to-bedside review: Carbon dioxide. Reviews [DOI] [Details]
(2010) Hypocapnia and the injured brain: More harm than benefit.
Curley, G,Kavanagh, BP,Laffey, JG (2010) Hypocapnia and the injured brain: More harm than benefit. Reviews [DOI] [Details]
(2010) Hypercapnia and Acidosis in Sepsis A Double-edged Sword?.
Curley, G,Contreras, M,Nichol, AD,Higgins, BD,Laffey, JG (2010) Hypercapnia and Acidosis in Sepsis A Double-edged Sword?. Reviews [Details]
(2005) Bench-to-bedside review: Permissive hypercapnia.
O'Croinin, D,Chonghaile, MN,Higgins, B,Laffey, JG (2005) Bench-to-bedside review: Permissive hypercapnia. Reviews [DOI] [Details]
(2005) Permissive hypercapnia: role in protective lung ventilatory strategies.
Ni Chonghaile, M,Higgins, B,Laffey, JG (2005) Permissive hypercapnia: role in protective lung ventilatory strategies. Reviews [Details]
(2005) Maternal brain death and somatic support.
Farragher, RA,Laffey, JG (2005) Maternal brain death and somatic support. Reviews [DOI] [Details]
(2005) Maternal brain death - an Irish perspective.
Farragher, R,Marsh, B,Laffey, JG (2005) Maternal brain death - an Irish perspective. Reviews [Details]
(2004) Permissive hypercapnia - role in protective lung ventilatory strategies.
Laffey, JG,O'Croinin, D,McLoughlin, P,Kavanagh, BP (2004) Permissive hypercapnia - role in protective lung ventilatory strategies. Reviews [DOI] [Details]
(2002) The systemic inflammatory response to cardiac surgery - Implications for the anesthesiologist.
Laffey, JG,Boylan, JF,Cheng, DCH (2002) The systemic inflammatory response to cardiac surgery - Implications for the anesthesiologist. Reviews [Details]

Honours and Awards

  Year Title Awarding Body
2008 Keynote speaker, Drager Medal Lecture Association of Anaesthetists of Graeat Britain and Ireland
2000 Young Investigator Award American Society of Critical Care Anesthesiologists
1999 Hynek Rothbart Research Prize Dept of Anesthesia, University of Toronto

Professional Associations

  Association Function From / To
European Society of Intensive Care Medicine Deputy Chairman, Acute Respiratory Failure Section 01-OCT-11 / 30-SEP-13
Irish Critical Care Trials Group Deputy Chair 01-JAN-10 / 31-DEC-12

Committees

  Committee Function From / To
Final Fellowship Examination in Anaesthesia, College of Anaesthetists Examiner /
Academic Anaesthesia Committee, College of Anaesthetists Member /
Intensive Care Society of Ireland Council Member /
Anaesthesiology and Pain Medicine Expert Review Panel, F1000 Medicine Faculty Member /
Society for Education in Anesthesia Member /
Cochrane Anaesthesia Research Group Member /
Association of Anaesthetists of Great Britain and Ireland Member /
International Anaesthesia Research Society Member /
European Society of Intensive Care Medicine Member /
American Thoracic Society Member /
Intensive Care Society of Ireland Council Member /

Education

  Year Institution Qualification Subject
1989 NUI Galway BSc Biochemistry
1992 NUI Galway Bachelor of Medicine Medicine
2001 Institute Of Public Administration, Dublin Master of Arts Healthcare Management
2001 NUI Galway Doctor of Medicine Medicine

Teaching Interests