Health Data Science is an emerging discipline, combining Biostatistics, Bioinformatics, Applied Mathematics and Computer Science, where skilled people are in extremely high demand due to data-led innovations across the sector.  Health related data are generated from many sources including observational studies, clinical trials, computational biology, electronic medical records, health care claims, genetic and genomic epidemiology, environmental health, sports science and climate change. The Sonraí Health Data Science Research Cluster in the School of Mathematical and Statistical Sciences is at the forefront of this development with internationally recognised expertise in this discipline, evidenced by the over €40 million in health research funding, a wealth of highly impactful publications and software, extensive graduate supervision and international collaborations.