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Courses
Courses
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University Life
University Life
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About University of Galway
About University of Galway
Since 1845, University of Galway has been sharing the highest quality teaching and research with Ireland and the world. Find out what makes our University so special – from our distinguished history to the latest news and campus developments.
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Colleges & Schools
Colleges & Schools
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Research & Innovation
Research & Innovation
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Business & Industry
Guiding Breakthrough Research at University of Galway
We explore and facilitate commercial opportunities for the research community at University of Galway, as well as facilitating industry partnership.
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Alumni & Friends
Alumni & Friends
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Community Engagement
Community Engagement
At University of Galway, we believe that the best learning takes place when you apply what you learn in a real world context. That's why many of our courses include work placements or community projects.
Summer Scholarships
Summer Scholarship
The Infectious Disease Section in the School of Biological and Chemical Sciences is sponsoring a summer scholarship for 3rd year undergraduates in a related programme at University of Galway. The interdisciplinary projects will be relevant to the theme of infectious disease and will promote greater cooperation and collaboration between different research areas.
The scholarship student will gain experience in multidisciplinary and interdisciplinary research and will develop valuable research skills during their scholarship experience. The student will be invited to present a poster of their project at the School Research Day at the end of semester 1. The project will be for 8 weeks full-time during summer 2023 and will take place between two research groups in the Infectious Disease Section. The student stipend is €2,000, payable monthly, and €500 will be available for consumables to support the project.
Project 1: Oligopeptide-modified oligonucleotides as targeted therapeutics for MRSA infections
The relentless rise of antimicrobial resistant (AMR) infections constitutes a leading threat to public health that must be counteracted by the development of novel antibacterial agents and alternative approaches. Staphylococcus aureus is a significant cause of both morbidity and mortality worldwide responsible for antibiotic resistant infections in a wide variety of organ systems. Identification and exploitation of new targets to improve the treatment options for AMR infections is a necessity. This 8-week project will focus on evaluating the potential of chimeric antisense oligonucleotides (ASOs) on growth inhibition of S. aureus, which is on the World Health Organisation’s list of priority pathogens. The overarching objective is to evaluate the hypothesis that ASOs targeting essential genes have therapeutic potential as inhibitors of growth of S. aureus. Chimeric ASOs will undergo modification with oligopeptides in collaboration with Prof. Paul Murphy (Chemistry) to facilitate delivery into bacterial cells. The activity of peptide modified ASOs will be tested against Staphylococcal species in Prof. James P. O’Gara’s lab (Microbiology). Additionally, new targets for ASOs will be identified bioinformatically. Exploiting inter-disciplinary research with new technologies to counter antibiotic resistance by targeting genes essential for growth will lay the foundations for therapeutic strategies to improve treatment of AMR infections. Lab supervisor: Dr. Merve S. Zeden (MicrobiologyAcademic supervisors: Prof. Paul Murphy (Chemistry) and Prof. James P. O'Gara (Microbiology)
Please contact Prof. Murphy (paul.v.murphy@universityofgalway.ie) or Prof. O’Gara (jamesp.ogara@universityofgalway.ie) with relevant questions.
Apply
To apply, please submit your CV and the names of 2 referees to Dr. Zeden (merve.zeden@universityofgalway.ie)
Deadline
Friday 28th April 2023 @5 pm - Interviews will be held the following week
Start Date
Projects start date will be no later than 1st June and finish no later than 4th August 2023.
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