2020 Investigating Interactions Between Nitrosative Stress and Human Endogenous Retrovirus K in Cancer Progression

Dr Glynn is a graduate of Dublin City University (BSC and PHD) and obtained a MPH from University College Dublin. She was previously an All-Ireland NCI Cancer Prevention Fellow and a Visiting Fellow in the Laboratory of Human Carcinogenesis and the Radiation Biology Branch at the National Cancer Institute, National Institutes of Health in Bethesda, Maryland, USA. She is currently a Lecturer Above the Bar in Pathology in the School of Medicine, NUI Galway. Her research combines molecular pathology, molecular epidemiology and basic cell biology to better understand the role of inflammation in the acquisition of invasive, aggressive phenotypes. She discovered a role for nitrosative stress in driving the transition of hormone receptor negative breast cancer to a metastatic phenotype. Recent research has focused on the role of nitrosative stress in the regulation of human endogenous retrovirus K and its contribution to the metastatic phenotype. She has received a number of grants including a SFI Career Development Award, Breast Cancer Now Project and PhD Grants, and Irish Cancer Society Funding. The main focus of her laboratory is to identify the role of redox, inflammation and endogenous retroviruses in breast and prostate cancer progression.

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