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Staff Profiles

Dr Laura Barkley

BSc, PhD

Contact Details

Lecturer
Lambe Institute for Translational Research
National University of Ireland, Galway
M: 0872616470
E: laura.barkley@nuigalway.ie

researcher

Biography

Peer Reviewed Journals

	Year	Publication
	(2020)	'Targeting stromal cell Syndecan-2 reduces breast tumour growth, metastasis and limits immune evasion' Loftus P;Watson L;Deedigan LM;Camarillo-Retamosa E;Dwyer RM;O'Flynn L;Griffin M;O'Brien T;Kerin M;Elliman SJ;Barkley LR; (2020) 'Targeting stromal cell Syndecan-2 reduces breast tumour growth, metastasis and limits immune evasion'. International Journal Of Cancer, [DOI] [Details]
	(2014)	'Selective repression of the oncogene cyclin D1 by the tumor suppressor miR-206 in cancers' Elliman SJ, Howley BV, Mehta DS, Fearnhead HO, Kemp DM, Barkley LR (2014) 'Selective repression of the oncogene cyclin D1 by the tumor suppressor miR-206 in cancers'. Oncogene, 3 [DOI] [Details]
	(2013)	'MicroRNA-29a regulates the benzo[a]pyrene dihydrodiol epoxide-induced DNA damage response through Cdc7 kinase in lung cancer cells' Barkley LR, Santocanale C (2013) 'MicroRNA-29a regulates the benzo[a]pyrene dihydrodiol epoxide-induced DNA damage response through Cdc7 kinase in lung cancer cells'. Oncogene, 2 [DOI] [Details]
	(2012)	'c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Pol eta recruitment to stalled replication forks' Barkley, LR;Palle, K;Durando, M;Day, TA;Gurkar, A;Kakusho, N;Li, JY;Masai, H;Vaziri, C (2012) 'c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Pol eta recruitment to stalled replication forks'. Molecular Biology Of The Cell, 23 :1943-1954 [DOI] [Details]
	(2010)	'A novel role for Fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells' Song IY;Barkley LR;Day TA;Weiss RS;Vaziri C; (2010) 'A novel role for Fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells'. Cell Cycle, 9 (12) [DOI] [Details]
	(2010)	'Phosphorylated Rad18 directs DNA polymerase ¿ to sites of stalled replication' Day TA;Palle K;Barkley LR;Kakusho N;Zou Y;Tateishi S;Verreault A;Masai H;Vaziri C; (2010) 'Phosphorylated Rad18 directs DNA polymerase ¿ to sites of stalled replication'. Journal Of Cell Biology, 191 (5) [DOI] [Details]
	(2009)	'Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells' Barkley LR;Song IY;Zou Y;Vaziri C; (2009) 'Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells'. Cell Cycle, 8 (10) [DOI] [Details]
	(2007)	'Cdc6 is a rate-limiting factor for proliferative capacity during HL60 cell differentiation' Barkley LR;Hong HK;Kingsbury SR;James M;Stoeber K;Williams GH; (2007) 'Cdc6 is a rate-limiting factor for proliferative capacity during HL60 cell differentiation'. Experimental Cell Research, 313 (17) [DOI] [Details]
	(2007)	'Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts' Barkley LR;Ohmori H;Vaziri C; (2007) 'Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts'. Cell Biochemistry And Biophysics, 47 (3) [DOI] [Details]
	(2006)	'Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest' Bi X;Barkley LR;Slater DM;Tateishi S;Yamaizumi M;Ohmori H;Vaziri C; (2006) 'Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest'. Molecular And Cellular Biology, 26 (9) [DOI] [Details]
	(2006)	'The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism' Liu, PJ;Barkley, LR;Day, T;Bi, XH;Slater, DM;Alexandrow, MG;Nasheuer, HP;Vaziri, C (2006) 'The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism'. Journal Of Biological Chemistry, 281 :30631-30644 [DOI] [Details]