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Biological and Chemical Sciences

Dr. Lucy Byrnes


 
researcher
 

Biography

2016 - Professor of Biochemistry                                            2012 - Dean of Graduate Studies

Research Interests

Developmental biology, gene expression in the early zebrafish embryo, role of IGF signalling in zebrafish, molecular and cellular basis of cardiovascular disease in zebrafish. 

Research Projects

  Project Start Date End Date
IRCSET SHAUN OBOYLE PHD LUCY BYRNES 08-SEP-03 30-APR-09
MF2002 MF85 02 M LUCY BYRNES 01-NOV-02 29-NOV-04
930 ST 98 529 TEPPS BYRNE TUOHY 15-MAR-99 01-OCT-01
SFI OVERHEADS EQUIPMENT LUCY BYRNES 01-JAN-08 30-JUN-08
NANOR, A NOVEL VERTEBRATE WITH A ROLE IN CARDIOVAS 01-SEP-07 28-FEB-11
SFI IGF SIGNALS IN VERTEBRATE EMBRYO L BYRNES 01-AUG-05 31-JAN-09
MF2003 MF76 03 M LUCY BYRNES 01-DEC-03 29-JAN-09
IRCSET EMBARK SCHOLARSHIP 2007-2010 MELISSA WALSH 01-OCT-07 30-SEP-12
MF2004 MF60 04 LUCY BYRNES 01-OCT-04 20-JUL-07
978 HEA BIOMED CENTRE P05 1 SMITH 01-OCT-99 31-MAR-09
AQUACHARR DEV A C L BYRNE 01-JAN-94 30-JUL-16
EI SC 2002 448 IGF 1 RECEPTOR L BYRNES 01-OCT-02 30-JUL-06
989 MF 12 01 M TRANS FACTORS BYRNES 01-SEP-01 29-NOV-04
EU AQUACHARR L BYRNE 01-DEC-96 30-JUN-09
SIGNALS IN EMBRYONIC SHIELD OF ZEBRATISH EMBRYOS 01-OCT-06 21-APR-09
989 MF 8 00 L BYRNES BIO 01-MAY-00 29-NOV-04
PRTLI3 BMES 2 1B BYRNES 01-JUL-02 28-JAN-08
SC 2003 461 APR IN RAINBOW TROUT L BYRNES 30-SEP-03 30-DEC-06

Peer Reviewed Journals

  Year Publication
(1990) 'ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN - CDNA SEQUENCE, EVOLUTION, AND TISSUE EXPRESSION'
BYRNES, L;GANNON, F (1990) 'ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN - CDNA SEQUENCE, EVOLUTION, AND TISSUE EXPRESSION'. Dna And Cell Biology, 9 :647-655 [Details]
(1991) 'THE SALMON GENE ENCODING APOLIPOPROTEIN-A-I - CDNA SEQUENCE, TISSUE EXPRESSION AND EVOLUTION'
POWELL, R;HIGGINS, DG;WOLFF, J;BYRNES, L;STACK, M;SHARP, PM;GANNON, F (1991) 'THE SALMON GENE ENCODING APOLIPOPROTEIN-A-I - CDNA SEQUENCE, TISSUE EXPRESSION AND EVOLUTION'. Gene, 104 :155-161 [Details]
(2002) 'Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development'
Brabazon, ED;Bree, RT;Carton, MW;Grealy, M;Byrnes, L (2002) 'Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development'. Biochimica Et Biophysica Acta-Gene Structure And Expression, 1576 :203-208 [Details]
(2002) 'Zebrafish insulin-like growth factor-I receptor: molecular cloning and developmental expression'
Ayaso, E;Nolan, CM;Byrnes, L (2002) 'Zebrafish insulin-like growth factor-I receptor: molecular cloning and developmental expression'. Molecular And Cellular Endocrinology, 191 :137-148 [Details]
(2002) 'Expressed sequence tags in larval Arctic charr (Salvelinus alpinus)'
Carton, MW;Schmitz, M;Cutts, CJ;Kelly, AK;Hill, JA;Brabazon, ED;Adams, CE;Byrnes, L (2002) 'Expressed sequence tags in larval Arctic charr (Salvelinus alpinus)'. Fish Physiology And Biochemistry, 26 :231-238 [Details]
(2004) 'Insulin-like growth factor (IGF) signalling is required for early dorso-anterior development of the zebrafish embryo'
Eivers, E;McCarthy, K;Glynn, C;Nolan, CM;Byrnes, L (2004) 'Insulin-like growth factor (IGF) signalling is required for early dorso-anterior development of the zebrafish embryo'. International Journal Of Developmental Biology, 48 :1131-1140 [DOI] [Details]
(2004) 'Three-dimensional structure of a thermostable native cellobiohydrolase, CBHIB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii'
Grassick, A;Murray, PG;Thompson, R;Collins, CM;Byrnes, L;Birrane, G;Higgins, TM;Tuohy, MG (2004) 'Three-dimensional structure of a thermostable native cellobiohydrolase, CBHIB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii'. European Journal Of Biochemistry, 271 :4495-4506 [DOI] [Details]
(2006) 'Mannose 6-phosphate receptors in an ancient vertebrate, zebrafish'
Nolan, CM;McCarthy, K;Eivers, E;Jirtle, RL;Byrnes, L (2006) 'Mannose 6-phosphate receptors in an ancient vertebrate, zebrafish'. Development Genes And Evolution, 216 :144-151 [DOI] [Details]
(2007) 'Molecular cloning and expression analysis of two distinct beta-glucosidase genes, bg1 and aven1, with very different biological roles from the thermophilic, saprophytic fungus Talaromyces emersonii'
Collins, CM;Murray, PG;Denman, S;Morrissey, JP;Byrnes, L;Teeri, TT;Tuohy, MG (2007) 'Molecular cloning and expression analysis of two distinct beta-glucosidase genes, bg1 and aven1, with very different biological roles from the thermophilic, saprophytic fungus Talaromyces emersonii'. Mycological Research, 111 :840-849 [DOI] [Details]
(2013) 'Effect of Nanoparticle Stabilization and Physicochemical Properties on Exposure Outcome: Acute Toxicity of Silver Nanoparticle Preparations in Zebrafish (Danio rerio)'
Cunningham, S;Brennan-Fournet, ME;Ledwith, D;Byrnes, L;Joshi, L (2013) 'Effect of Nanoparticle Stabilization and Physicochemical Properties on Exposure Outcome: Acute Toxicity of Silver Nanoparticle Preparations in Zebrafish (Danio rerio)'. Environmental Science & Technology, 47 :3883-3892 [DOI] [Details]
(2013) 'Effect of Nanoparticle Stabilization and Physicochemical Properties on Exposure Outcome: Acute Toxicity of Silver Nanoparticle Preparations in Zebrafish (Danio rerio)'
Cunningham, S,Brennan-Fournet, ME,Ledwith, D,Byrnes, L,Joshi, L (2013) 'Effect of Nanoparticle Stabilization and Physicochemical Properties on Exposure Outcome: Acute Toxicity of Silver Nanoparticle Preparations in Zebrafish (Danio rerio)'. Environmental Science & Technology, 47 :3883-3892 [DOI] [Details]
(2012) 'Loss of plakophilin 2 disrupts heart development in zebrafish'
Moriarty, MA,Ryan, R,Lalor, P,Dockery, P,Byrnes, L,Grealy, M (2012) 'Loss of plakophilin 2 disrupts heart development in zebrafish'. International Journal Of Developmental Biology, 56 :711-718 [DOI] [Details]
(2010) 'Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos'
Hartnett L, Glynn C, Nolan CM, Grealy M, Byrnes L (2010) 'Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos'. International Journal Of Developmental Biology, 54 (4):573-583 [DOI] [Details]
(2009) 'Regulation of expression of zebrafish (Danio rerio) insulin-like growth factor 2 receptor: implications for evolution at the IGF2R locus'
Tsalavouta, M,Astudillo, O,Byrnes, L,Nolan, CM (2009) 'Regulation of expression of zebrafish (Danio rerio) insulin-like growth factor 2 receptor: implications for evolution at the IGF2R locus'. Evolution & Development, 11 :547-559 [DOI] [Details]
(2009) 'Plakoglobin has both structural and signalling roles in zebrafish development'
Martin ED, Moriarty MA, Byrnes L and M Grealy (2009) 'Plakoglobin has both structural and signalling roles in zebrafish development'. Developmental Biology, [Details]
(2008) 'Molecular cloning and developmental expression of plakophilin 2 in zebrafish'
Moriarty MA, Martin ED, Byrnes L and M Grealy (2008) 'Molecular cloning and developmental expression of plakophilin 2 in zebrafish'. Biochimica Et Biophysica Acta, 367 :124-129 [Details]
(2008) 'Mouse induced pluripotent stem cells'
Geoghehan E Byrnes L (2008) 'Mouse induced pluripotent stem cells'. International Journal Of Developmental Biology, 52 :1015-1022 [Details]
(2007) 'Identification of zygotic genes expressed at the midblastula transition in zebrafish'
O'Boyle, S,Bree, RT,McLoughlin, S,Grealy, M,Byrnes, L (2007) 'Identification of zygotic genes expressed at the midblastula transition in zebrafish'. Biochemical And Biophysical Research Communications, 358 :462-468 [DOI] [Details]
(2007) 'Molecular cloning and expression analysis of two distinct beta-glucosidase genes, bg1 and aven1, with very different biological roles from the thermophilic, saprophytic fungus Talaromyces emersonii'
Collins, CM,Murray, PG,Denman, S,Morrissey, JP,Byrnes, L,Teeri, TT,Tuohy, MG (2007) 'Molecular cloning and expression analysis of two distinct beta-glucosidase genes, bg1 and aven1, with very different biological roles from the thermophilic, saprophytic fungus Talaromyces emersonii'. Mycological Research, 111 :840-849 [DOI] [Details]
(2006) 'Mannose 6-phosphate receptors in an ancient vertebrate, zebrafish'
Nolan, CM,McCarthy, K,Eivers, E,Jirtle, RL,Byrnes, L (2006) 'Mannose 6-phosphate receptors in an ancient vertebrate, zebrafish'. Development Genes And Evolution, 216 :144-151 [DOI] [Details]
(2005) 'nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish'
Bree, RT,McLoughlin, S,Jin, SW,McMeel, OM,Stainier, DYR,Grealy, M,Byrnes, L (2005) 'nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish'. Biochemical And Biophysical Research Communications, 333 :722-728 [DOI] [Details]
(2005) 'nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish'
Bree RT, McLoughlin S, Jin SW, McMeel OM, Stainier DY, Grealy M, Byrnes L (2005) 'nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish'. Biochem, 333 (3):722-728 [DOI] [Details]
(2004) 'Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii'
Grassick, A.,Murray, P.G.,Thompson,R.,Collins, C.M.,Byrnes, L.,Birrane, G.,Higgins, T.M.,Tuohy, M.G. (2004) 'Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii'. European Journal of Biochemistry, 271 (22) [Details]
(2004) 'Insulin-like growth factor (IGF) signalling is required for early dorso-anterior development of the zebrafish embryo'
Eivers, E,McCarthy, K,Glynn, C,Nolan, CM,Byrnes, L (2004) 'Insulin-like growth factor (IGF) signalling is required for early dorso-anterior development of the zebrafish embryo'. International Journal Of Developmental Biology, 48 :1131-1140 [DOI] [Details]
(2002) 'Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development'
Brabazon ED, Bree RT, Carton MW, Grealy M, Byrnes L (2002) 'Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development'. Biochimica Et Biophysica Acta, 1576 (1-2):203-208 [Details]
(2002) 'Expressed sequence tags in larval Arctic charr (Salvelinus alpinus)'
Carton, MW,Schmitz, M,Cutts, CJ,Kelly, AK,Hill, JA,Brabazon, ED,Adams, CE,Byrnes, L (2002) 'Expressed sequence tags in larval Arctic charr (Salvelinus alpinus)'. Fish Physiology And Biochemistry, 26 :231-238 [Details]
(2002) 'Zebrafish insulin-like growth factor-I receptor: molecular cloning and developmental expression'
Ayaso, E,Nolan, CM,Byrnes, L (2002) 'Zebrafish insulin-like growth factor-I receptor: molecular cloning and developmental expression'. Molecular And Cellular Endocrinology, 191 :137-148 [DOI] [Details]
(2002) 'Cellular longevity: role of apoptosis and replicative senescence'
Bree RT Stenson C Grealy M Byrnes L Gorman AM Samali A (2002) 'Cellular longevity: role of apoptosis and replicative senescence'. Biogerontology, 3 :195-206 [Details]
(2000) 'Atlantic Salmon HNF-3/forkhead: cDNA sequence, evolution, expression, and functional analysis'
Stenson, C., McNair, A., Byrnes, L., Murphy, M., Smith, T., and Gannon, F. (2000) 'Atlantic Salmon HNF-3/forkhead: cDNA sequence, evolution, expression, and functional analysis'. DNA AND CELL BIOLOGY, 19 :59-68 [Details]
(1998) 'Transcriptional regulation of expression of the rainbow trout albumin gene by estrogen'
Fluoriot G, ducouret B, Byrnes L and Valotaire Y (1998) 'Transcriptional regulation of expression of the rainbow trout albumin gene by estrogen'. J Mol Endocrinol, 20 :355-362 [Details]
(1995) 'Salmon HNF1:cDNA sequene, evolution, tissue specificity and binding to the salmon serum albumin promoter'
Dercykere F, Byrnes L, Wagner A, McMorrow T and Gannon, F (1995) 'Salmon HNF1:cDNA sequene, evolution, tissue specificity and binding to the salmon serum albumin promoter'. J Mol Biol, 2247 :1-10 [Details]
(1994) 'An analysis of highly expressed salmon liver genes during smoltification in the Atlantic salmon (Salmo salar L)'
Hardiman G, Byrnes L and Gannon F (1994) 'An analysis of highly expressed salmon liver genes during smoltification in the Atlantic salmon (Salmo salar L)'. Molecular Marine Biol Biotech, 3 :51-56 [Details]
(1992) 'Sequence analysis of a second cDNA for salmon serum albumin'
Byrnes L Gannon F (1992) 'Sequence analysis of a second cDNA for salmon serum albumin'. Gene, 120 :319-320 [Details]
(1991) 'THE SALMON GENE ENCODING APOLIPOPROTEIN-A-I - CDNA SEQUENCE, TISSUE EXPRESSION AND EVOLUTION'
POWELL, R,HIGGINS, DG,WOLFF, J,BYRNES, L,STACK, M,SHARP, PM,GANNON, F (1991) 'THE SALMON GENE ENCODING APOLIPOPROTEIN-A-I - CDNA SEQUENCE, TISSUE EXPRESSION AND EVOLUTION'. Gene, 104 :155-161 [Details]
(1991) 'Sequence of a cDNA clone encoding an Atlantic salmon ribodomal protein'
Powell R, Byrnes L and Gannon, F (1991) 'Sequence of a cDNA clone encoding an Atlantic salmon ribodomal protein'. Gene, 101 :303-304 [Details]
(1990) 'A rapid procedure to isolate major abundance mRNA transcripts and study the transcription profile of a tissue'
Powell, R, Byrnes L, Barry T and Gannon, F (1990) 'A rapid procedure to isolate major abundance mRNA transcripts and study the transcription profile of a tissue'. Technique, 2 :213-215 [Details]
(1990) 'ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN - CDNA SEQUENCE, EVOLUTION, AND TISSUE EXPRESSION'
BYRNES, L,GANNON, F (1990) 'ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN - CDNA SEQUENCE, EVOLUTION, AND TISSUE EXPRESSION'. Dna And Cell Biology, 9 :647-655 [Details]
(1990) 'Transgenic fish'
Powell R Byrnes L Gannon F (1990) 'Transgenic fish'. The Genetic Engineer And Biotechnologist, 10 :7-9 [Details]
(1987) 'Chicken apolipoprotein A-I; cDNA sequence, tissue expression and evolution'
Byrnes L, Luo CC, Li WH, Yang CY and Chan L (1987) 'Chicken apolipoprotein A-I; cDNA sequence, tissue expression and evolution'. Biochem Biophys Res Comm, 148 :485-492 [Details]

Books

  Year Publication
(2012) Developing an Institutional Framework for Supporting Supervisors of Research Students: Supervisor best practice.
Kelly, A., Byrnes, L., Campbell, V., Carlton, J., Harkin, S., Leonard, AM., Morgan, P., O’Farrell, C., O’Mahony, C (2012) Developing an Institutional Framework for Supporting Supervisors of Research Students: Supervisor best practice. Cork: NAIRTL. [Details]

Book Chapters

  Year Publication
(1995) 'Preparation of DNA probes'
Byrnes, L., Enenkel, B., Gannon F., and Smith, T.J. (1995) 'Preparation of DNA probes' In: Gene Probes: A Practical Approach. Oxford, UK: Oxford University Press. [Details]
(1995) 'Preparation of DNA for use as probes'
Byrnes L, Enenkel B, Gannon F and Smith T (1995) 'Preparation of DNA for use as probes' In: Gene Probes 1: A Practical Approach. IRL Press. [Details]
(1993) 'The isolation and structure of liver and globin genes from Atlantic salmon'
Wagner A Deryckere F Hardiman G Byrnes L Gannon F (1993) 'The isolation and structure of liver and globin genes from Atlantic salmon' In: Aquaculture: Fundamental and Applied Research. Washington: American Biophysical Union. [Details]

Conference Publications

  Year Publication
(1990) 5TH EUROPEAN CONGRESS ON BIOTECHNOLOGY, PROCEEDINGS, VOLS 1 AND 2
POWELL, R;BYRNES, L;GANNON, F (1990) LIVER GENE-EXPRESSION - CLONING OF ABUNDANT MESSENGER-RNA TRANSCRIPTS FROM THE LIVER OF ATLANTIC SALMON (SALMO SALAR), IDENTIFICATION OF SALMON APOLIPOPROTEIN A-1 GENE 5TH EUROPEAN CONGRESS ON BIOTECHNOLOGY, PROCEEDINGS, VOLS 1 AND 2 , pp.453-456 [Details]
(1996) BIOCHEMICAL SOCIETY TRANSACTIONS
Stenson, C;McNair, A;Byrnes, L;Gannon, F (1996) Cloning of an Atlantic salmon transcription factor BIOCHEMICAL SOCIETY TRANSACTIONS , pp.106-106 [Details]
(1990) LIVER GENE-EXPRESSION - CLONING OF ABUNDANT MESSENGER-RNA TRANSCRIPTS FROM THE LIVER OF ATLANTIC SALMON (SALMO SALAR), IDENTIFICATION OF SALMON APOLIPOPROTEIN A-1 GENE
POWELL, R,BYRNES, L,GANNON, F,Christiansen, C,Munck, L,Villadsen, J (1990) 5TH EUROPEAN CONGRESS ON BIOTECHNOLOGY, PROCEEDINGS, VOLS 1 AND 2 LIVER GENE-EXPRESSION - CLONING OF ABUNDANT MESSENGER-RNA TRANSCRIPTS FROM THE LIVER OF ATLANTIC SALMON (SALMO SALAR), IDENTIFICATION OF SALMON APOLIPOPROTEIN A-1 GENE , pp.453-456 [Details]
(2013) 8th European Zebrafish Conference, Barcelona
Ryan, R., Rink, E., O’Connor, E., Stainier, DY., Byrnes, L. & Grealy, M. (2013) Development of a zebrafish model for ARVC using TALEN targeting 8th European Zebrafish Conference, Barcelona [Details]
(2011) British Society for Developmental Biology Spring meeting, Canterbury
Ryan, R. Moriarty, M.A., Byrnes, L. & Grealy, M. (2011) Investigation of the signalling effects of plakoglobin and plakophilin 2 knockdown in zebrafish British Society for Developmental Biology Spring meeting, Canterbury [Details]
(2010) 1st European Zebrafish PI meeting, Padova, Italy
Martin, E.E., Moriarty, M.A., Byrnes, L. and Grealy, M. (2010) Modelling the congenital heart disorder arrhythmogenic right ventricular cardiomyopathy (ARVC) in zebrafish 1st European Zebrafish PI meeting, Padova, Italy [Details]
(2009) The 6th European Zebrafish Development and Genetics Meeting, Rome
Morairty, M.A., Martin, E.D., Byrnes, L. & Grealy, M. (2009) Modelling Arrhythmogenic right ventricular cardiomyopathy in zebrafish The 6th European Zebrafish Development and Genetics Meeting, Rome [Details]
(2009) 16th International Society of Developmental Biologists Congress, Edinburgh
Moriarty, M.A., Byrnes, L. & Grealy, M. (2009) Effects of plakophilin -2 knockdown on zebrafish embryonic development 16th International Society of Developmental Biologists Congress, Edinburgh [Details]
(2009) 12th INDB Meeting, NUI, Galway (oral presentation.)
Moriarty, M.A., Martin, E.D., Byrnes, L. and Grealy, M. (2009) Modelling arrhythmogenic right ventricular cardiomyopathy in zebrafish 12th INDB Meeting, NUI, Galway (oral presentation.) [Details]
(2008) The 8th International Meeting on Zebrafish Development and Genetics, Madison
O’Boyle, S., Grealy, M., and Byrnes, L. (2008) The novel gene, nanor, acts via the Nodal pathway to direct formation of the cardiac outflow tract, patterning of the parapineal, and separation of the eye-field The 8th International Meeting on Zebrafish Development and Genetics, Madison [Details]
(2007) The 5th European Zebrafish Development and Genetics Meeting, Amsterdam
O’Boyle, S., Grealy, M., and Byrnes, L. (2007) The novel gene, nanor, has a role in cardiovascular development and left-right asymmetry The 5th European Zebrafish Development and Genetics Meeting, Amsterdam [Details]
(2007) 10th INDB meeting University College Cork (poster presentation)
Moriarty, M.A., Martin, E.D., Byrnes, L. and Grealy, M. (2007) Role of Plakophilin-2 in zebrafish development 10th INDB meeting University College Cork (poster presentation) [Details]
(2006) BSDB autumn meeting, Dundee
Hartnett, L., McCarthy, K., Glynn, C., Grealy, M., Nolan, C., Byrnes, L. (2006) Targeted knockdown of IGF-2 disrupts cardiovascular development in zebrafish embryos BSDB autumn meeting, Dundee [Details]
(2006) 8th INDB meeting, NUI Galway
Hartnett, L., McCarthy, K., Glynn, C., Grealy, M., Nolan, C., Byrnes, L. (2006) Targeted knockdown of two IGF-2 disrupts cardiovascular development in zebrafish embryos 8th INDB meeting, NUI Galway [Details]
(2005) Developmental Biology 283 620-621
McCarthy K Glynn C Hartnett L Grealy M Nolan C Byrnes L (2005) The role of insulin-like growth factor-2 (IGF-2) in zebrafish embryonic development Developmental Biology 283 620-621 [Details]
(2005) 4th European Zebrafish Genetics and Development meeting, Dresden
Hartnett, L., McCarthy, K., Glynn, C., Grealy, M., Nolan, C. and Byrnes, L. (2005) Insulin-like growth factors are involved in heart and somite development in zebrafish embryonic development 4th European Zebrafish Genetics and Development meeting, Dresden [Details]
(2005) The 4th European Zebrafish Development and Genetics Meeting, Dresden
O’Boyle, S., Bree, R. T., McLoughlin, S., Grealy, M., and Byrnes, L. (2005) A study of gene expression at the midblastula transition in zebrafish The 4th European Zebrafish Development and Genetics Meeting, Dresden [Details]
(2005) The Royal Academy of Medicine in Ireland Summer Meeting, NUI Galway
O’Boyle, S., Bree, R. T., McLoughlin, S., Schindler, S., Müller, F., Grealy, M., and Byrnes, L. (2005) The developmental role of the first zebrafish genes activated during zebrafish development The Royal Academy of Medicine in Ireland Summer Meeting, NUI Galway [Details]
(2004) Biosciences Meeting of Biochemical Society, Glasgow
McLoughlin S., Bree R.T., O'Boyle S., Grealy M., Byrnes L. (2004) Gene expression at the midblastula transition in zebrafish Biosciences Meeting of Biochemical Society, Glasgow [Details]
(2003) BioNet conference Galway
McLoughlin, S., Bree, R.T., Grealy, M. & Byrnes, L. (2003) Identification and characterisation of Cyclin dependent kinase 7 in Danio rerio embryos BioNet conference Galway [Details]
(2001) 2nd European conference on zebrafish genetics and development, London
Bree, RT., McMeel, O., Brabazon, E.D., Cairns, M., Smith, T., Grealy, M., & Byrnes, L. (2001) Characterisation of the molecular events occurring at the mid-blastula transition during zebrafish embryo development 2nd European conference on zebrafish genetics and development, London [Details]
(2001) 2nd European conference on zebrafish genetics and development, London
Brabazon, E.D., Bree, R.T., Grealy, M., & Byrnes, L. (2001) Characterisation of zebrafish cyclin dependent kinase 8:cDNA sequencing and expression studies 2nd European conference on zebrafish genetics and development, London [Details]
(2001) Biochem Soc Trans 29 135A
O'Connor D Byrnes L (2001) ONECUT domain transcription factors in the zebrafish Biochem Soc Trans 29 135A [Details]
(2001) British Societies for Cell and Developmental Biology Joint Spring Meeting
Brabazon, E.D., Byrnes, L. & Grealy, M. (2001) Cadherin and catenin expression and localization during early zebrafish embryo morphogenesis British Societies for Cell and Developmental Biology Joint Spring Meeting [Details]
(2000) Cold Spring Harbor, Zebrafish Development and Genetics Meeting
Brabazon, E.D., Byrnes, L. & Grealy, M. (2000) Expression and localization of cadherins and catenins during zebrafish embryo development Cold Spring Harbor, Zebrafish Development and Genetics Meeting [Details]
(1999) J Fish Biol 55A 244-245
Kelly A Schmitz M Hill J Cutts C Adams C Byrnes L (1999) Molecular basis for variation in metabolic rate in juvenile charr J Fish Biol 55A 244-245 [Details]
(1999) Growth hormone and IGF Research 9 347
Ayaso E Nolan C Byrnes L (1999) Zebrafish IGF-1 receptor expression during development Growth hormone and IGF Research 9 347 [Details]
(1999) J Fish Biol 55A 247
O'Connor D Byrnes L (1999) CCAAT/enhancer binding protein in zebrafish J Fish Biol 55A 247 [Details]
(1997) Cold Spring Harbor, Zebrafish Development and Genetics Meeting
Brabazon, E.D., Byrnes, L. & Grealy, M. (1997) Expression and localization of cadherins and catenins during zebrafish embryo development Cold Spring Harbor, Zebrafish Development and Genetics Meeting [Details]
(1996) Biochem Soc Trans 24 1 106S
Stenson C McNair A Byrnes L Gannon F (1996) Cloning of an Atlantic salmon transcription factor Biochem Soc Trans 24 1 106S [Details]
(1996) Cloning of an Atlantic salmon transcription factor
Stenson, C,McNair, A,Byrnes, L,Gannon, F (1996) BIOCHEMICAL SOCIETY TRANSACTIONS Cloning of an Atlantic salmon transcription factor , pp.106-106 [Details]
(1990) Proc. 5th European Congress on Biotechnology 5 453-456
Powell R Byrnes L Gannon F (1990) Liver gene expression: cloning of abundant messenger RNA transcripts from the liver of Atlantic salmon (Salmo salar). Identification of salmon apolipoprotein A-1 gene Proc. 5th European Congress on Biotechnology 5 453-456 [Details]
(1987) Biochem Soc Trans 15 277-278
Abdul-Ahad W Byrnes L Gosling JP (1987) The use of Fab'-beta-lactamase conjugate in an enzyme-linked immunosorbent assay for bovine luteinizing hormone Biochem Soc Trans 15 277-278 [Details]

Abstract

  Year Publication
(2001) ONECUT domain transcription factors in the zebrafish. BIOCHEMICAL SOCIETY TRANSACTIONS.
O'Connor, D. and L. Byrnes (2001) ONECUT domain transcription factors in the zebrafish. BIOCHEMICAL SOCIETY TRANSACTIONS. Abstract [Details]

Conference Paper

  Year Publication
(2001) Characterisation of the molecular events occurring at the mid-blastula transition during zebrafish embryo development. 2nd European conference on zebrafish genetics and development.
Bree, R.T., McMeel, O., Brabazon, E.D., Cairns, M., Smith, T., Grealy, M. & Byrnes, L. (2001) Characterisation of the molecular events occurring at the mid-blastula transition during zebrafish embryo development. 2nd European conference on zebrafish genetics and development. London: Conference Paper [Details]

Conference Poster

  Year Publication
(2011) Investigation of the signalling effects of plakoglobin and plakophilin 2 knockdown in zebrafish.
Ryan, R. Moriarty, M.A., Byrnes, L. & Grealy, M. (2011) Investigation of the signalling effects of plakoglobin and plakophilin 2 knockdown in zebrafish. Conference Poster [Details]
(2006) Targeted knockdown of IGF-2 disrupts cardiovascular development in zebrafish embryos. BSDB Autumn Meeting.
Hartnett L, McCarthy K, Glynn C, Grealy M and Byrnes L (2006) Targeted knockdown of IGF-2 disrupts cardiovascular development in zebrafish embryos. BSDB Autumn Meeting. Dundee, Scotland: Conference Poster [Details]
(2006) Evidence of a phytopathogenic gene in the thermophoilic, saprophytic fungus Talaromyces emersonii. 8th European Fungal Genetics meeting.
Collins C, Murray P, Morrissey J, Byrnes L and M Tuohy (2006) Evidence of a phytopathogenic gene in the thermophoilic, saprophytic fungus Talaromyces emersonii. 8th European Fungal Genetics meeting. Austria: Conference Poster [Details]
(2006) Complex regulation of expression of an evolutionarily important gene: the zebrafish CI-MPR/IGF2R. 7th International meeting: Zebrafish Development and Genetics.
Tsalavouta M, Astudillo O, Byrnes L and Nolan C (2006) Complex regulation of expression of an evolutionarily important gene: the zebrafish CI-MPR/IGF2R. 7th International meeting: Zebrafish Development and Genetics. Madison, Wisconsin, USA: Conference Poster [Details]
(2005) A study of gene expression at the midblastula transition in zebrafish. 4th European zebrafish meeting.
O'Boyle S, Bree RT, McLoughlin S, Schindler S, Muller F, Grealy M and Byrnes L (2005) A study of gene expression at the midblastula transition in zebrafish. 4th European zebrafish meeting. Dresden, Germany: Conference Poster [Details]
(2005) Regulation of differential gene expression during zebrafish development by alternative transcription initiation complexes. 4th European zebrafish meeting.
Ferg M, Lovas A, Bree R, O'Boyle S, Byrnes L and Muller F (2005) Regulation of differential gene expression during zebrafish development by alternative transcription initiation complexes. 4th European zebrafish meeting. Dresden, Germany: Conference Poster [Details]
(2005) Insulin-like growth factors are involved in heart and somite development in zebrafish. 4th European zebrafish meeting.
Hartnett L, McCarthy K, Glynn C, Grealy M, Nolan C and Byrnes L (2005) Insulin-like growth factors are involved in heart and somite development in zebrafish. 4th European zebrafish meeting. Dresden, Germany: Conference Poster [Details]
(2005) Embryonic development in Atlantic salmon (Salmo salar). British Societies for Cell and Developmental Biology Joint Spring Meeting.
Reynolds T and Byrnes L (2005) Embryonic development in Atlantic salmon (Salmo salar). British Societies for Cell and Developmental Biology Joint Spring Meeting. University of Warwick, U.K: Conference Poster [Details]
(2005) Evolution of an imprinted gene: the mannose 6-phosphate/IGF2 receptor. Environmental Epigenomics, Imprinting and Disease susceptibility.
Nolan CM, Astudillo O, Callanan S, McCann A, Jirtle RL, Byrnes L and O'Sullivan F (2005) Evolution of an imprinted gene: the mannose 6-phosphate/IGF2 receptor. Environmental Epigenomics, Imprinting and Disease susceptibility. Durham, North Carolina, USA: Conference Poster [Details]
(2005) Evolution of an imprinted gene: the zebrafish mannose 6-phosphate/IGF2 receptor. 4th European zebrafish meeting.
Astudillo A, McCarthy K, Byrnes L and Nolan C (2005) Evolution of an imprinted gene: the zebrafish mannose 6-phosphate/IGF2 receptor. 4th European zebrafish meeting. Dresden, Germany: Conference Poster [Details]
(2004) Evolution of the cation-independent mannose 6-phosphate receptor: the zebrafish receptor. Gordon Conference on Lysosomes and Endocytosis.
Nolan C, McCarthy K, Byrnes L and Jirtle R (2004) Evolution of the cation-independent mannose 6-phosphate receptor: the zebrafish receptor. Gordon Conference on Lysosomes and Endocytosis. New Hampshire, USA: Conference Poster [Details]
(2004) Molecular characterisation and expression analysis of the cation independent mannose 6-phosphate receptor (CI-M6PR) in zebrafish. Joint meeting of Genetics Society and British Society for Developmental Biology.
McCarthy K, Eivers E, Nolan C and Byrnes L (2004) Molecular characterisation and expression analysis of the cation independent mannose 6-phosphate receptor (CI-M6PR) in zebrafish. Joint meeting of Genetics Society and British Society for Developmental Biology. University of Warwick, UK: Conference Poster [Details]
(2004) IGF signalling and neural development in the zebrafish embryo. Zebrafish Development & Genetics.
Eivers E, McCarthy K, Glynn C, Nolan CM and Byrnes L (2004) IGF signalling and neural development in the zebrafish embryo. Zebrafish Development & Genetics. University of Wisconsin-Madison, USA: Conference Poster [Details]
(2004) Gene expression at the midblastula transition in zebrafish. BioScience 2004 from molecules to organisms.
McLoughlin S, Bree RT, O'Boyle S, Grealy M, and Byrnes, L (2004) Gene expression at the midblastula transition in zebrafish. BioScience 2004 from molecules to organisms. Glasgow, UK: Conference Poster [Details]
(2004) Evolution of the mannose 6-phosphate/IGF2 receptor: a novel regulatory element?. 69th Cold Spring Harbor Symposium on Quantitative Biology: Epigenetics.
Nolan C, McCarthy K, Byrnes L and Jirtle R (2004) Evolution of the mannose 6-phosphate/IGF2 receptor: a novel regulatory element?. 69th Cold Spring Harbor Symposium on Quantitative Biology: Epigenetics. Cold Spring Harbor, New York, USA: Conference Poster [Details]
(2001) Cadherin and catenin expression and localisation during early zebrafish morphogenesis. Cell and Tissue Morphogenesis, British Societies for Cell and Developmental Biology Joint Spring Meeting.
Brabazon ED, Byrnes L and Grealy M (2001) Cadherin and catenin expression and localisation during early zebrafish morphogenesis. Cell and Tissue Morphogenesis, British Societies for Cell and Developmental Biology Joint Spring Meeting. University of Sussex, Brighton, UK: Conference Poster [Details]
(2001) Isolation and expression of a ONECUT domain transcription factor from the zebrafish. 2nd European conference on Zebrafish Genetics and Development.
D O'Connor and L Byrnes (2001) Isolation and expression of a ONECUT domain transcription factor from the zebrafish. 2nd European conference on Zebrafish Genetics and Development. University College London, UK: Conference Poster [Details]
(2001) Cadherin and catenin expression and localization during early zebrafish embryo morphogenesis. Cell and Tissue Morphogenesis, British Societies for Cell and Developmental Biology Joint Spring Meeting.
Brabazon ED, Byrnes L and M Grealy (2001) Cadherin and catenin expression and localization during early zebrafish embryo morphogenesis. Cell and Tissue Morphogenesis, British Societies for Cell and Developmental Biology Joint Spring Meeting. University of Sussex, Brighton, UK: Conference Poster [Details]
(2001) Characterisation of the molecular events occurring at the mid-blastula transition during zebrafish embryo development. 2nd European conference on Zebrafish Genetics and Development.
Bree RT, McMeel O, Brabazon ED, Cairns M, Smith T, Grealy M and L Byrnes (2001) Characterisation of the molecular events occurring at the mid-blastula transition during zebrafish embryo development. 2nd European conference on Zebrafish Genetics and Development. University College London, UK: Conference Poster [Details]
(2001) Molecular genetics of cellulase production in the filamentous fungus Talaromyces emersonii. 4th Carbohydrate Bioengineering Meeting.
Collins C, Murray PG, Byrnes L and Tuohy M (2001) Molecular genetics of cellulase production in the filamentous fungus Talaromyces emersonii. 4th Carbohydrate Bioengineering Meeting. Stockholm, Sweden: Conference Poster [Details]
(2001) Characterisation of Zebrafish Cyclin Dependent Kinase 8: cDNA Sequencing and Expression Studies. 2nd European conference on Zebrafish Genetics and Development.
E D Brabazon, R T Bree, M Grealy and L Byrnes (2001) Characterisation of Zebrafish Cyclin Dependent Kinase 8: cDNA Sequencing and Expression Studies. 2nd European conference on Zebrafish Genetics and Development. University College London, UK: Conference Poster [Details]
(2000) Cloning and developmental expression of the zebrafish IGF-I receptor. Zebrafish Development & Genetics.
Ayaso E, Nolan CM and L Byrnes (2000) Cloning and developmental expression of the zebrafish IGF-I receptor. Zebrafish Development & Genetics. Cold Spring Harbor, New York: Conference Poster [Details]
(2000) Expression and localization of cadherins and catenins during zebrafish embryo development. Zebrafish Development & Genetics.
Brabazon ED, Byrnes L and M Grealy (2000) Expression and localization of cadherins and catenins during zebrafish embryo development. Zebrafish Development & Genetics. Cold Spring Harbor, New York: Conference Poster [Details]

Meeting

  Year Publication
(2009) Effects of plakophilin 2 knockdown on zebrafish embryonic development.
Moriarty, MA,Byrnes, L,Grealy, M (2009) Effects of plakophilin 2 knockdown on zebrafish embryonic development. Meeting [DOI] [Details]
(2005) The role of insulin-like growth factor-2 (IGF-2) in zebrafish embryonic development.
McCarthy, K,Glynn, C,Hartnett, L,Nolan, C,Byrnes, L (2005) The role of insulin-like growth factor-2 (IGF-2) in zebrafish embryonic development. Meeting [Details]

Note

  Year Publication
(1991) SEQUENCE OF A CDNA CLONE ENCODING AN ATLANTIC SALMON RIBOSOMAL-PROTEIN.
POWELL, R;BYRNES, L;GANNON, F (1991) SEQUENCE OF A CDNA CLONE ENCODING AN ATLANTIC SALMON RIBOSOMAL-PROTEIN. AMSTERDAM: Note [Details]
(1992) SEQUENCE-ANALYSIS OF A 2ND CDNA-ENCODING ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN.
BYRNES, L;GANNON, F (1992) SEQUENCE-ANALYSIS OF A 2ND CDNA-ENCODING ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN. AMSTERDAM: Note [Details]
(1995) SALMON HNF1 - CDNA SEQUENCE, EVOLUTION, TISSUE-SPECIFICITY AND BINDING TO THE SALMON SERUM-ALBUMIN PROMOTER.
DERYCKERE, F;BYRNES, L;WAGNER, A;MCMORROW, T;GANNON, F (1995) SALMON HNF1 - CDNA SEQUENCE, EVOLUTION, TISSUE-SPECIFICITY AND BINDING TO THE SALMON SERUM-ALBUMIN PROMOTER. LONDON: Note [Details]
(1995) SALMON HNF1 - CDNA SEQUENCE, EVOLUTION, TISSUE-SPECIFICITY AND BINDING TO THE SALMON SERUM-ALBUMIN PROMOTER.
DERYCKERE, F,BYRNES, L,WAGNER, A,MCMORROW, T,GANNON, F (1995) SALMON HNF1 - CDNA SEQUENCE, EVOLUTION, TISSUE-SPECIFICITY AND BINDING TO THE SALMON SERUM-ALBUMIN PROMOTER. Note [Details]
(1992) SEQUENCE-ANALYSIS OF A 2ND CDNA-ENCODING ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN.
BYRNES, L,GANNON, F (1992) SEQUENCE-ANALYSIS OF A 2ND CDNA-ENCODING ATLANTIC SALMON (SALMO-SALAR) SERUM-ALBUMIN. Note [Details]
(1991) SEQUENCE OF A CDNA CLONE ENCODING AN ATLANTIC SALMON RIBOSOMAL-PROTEIN.
POWELL, R,BYRNES, L,GANNON, F (1991) SEQUENCE OF A CDNA CLONE ENCODING AN ATLANTIC SALMON RIBOSOMAL-PROTEIN. Note [Details]

Other Item

  Year Publication
(1993) The isolation and structure of liver and globin genes from Atlantic salmon. American Biophysical Union, Washington DC.
Wagner, A., Deryckere, F., Hardiman, G., Byrnes, L. and F. Gannon (1993) The isolation and structure of liver and globin genes from Atlantic salmon. American Biophysical Union, Washington DC. Other Item [Details]

Reviews

  Year Publication
(2002) Cellular longevity: role of apoptosis and replicative senescence.
Bree, RT;Stenson-Cox, C;Grealy, M;Byrnes, L;Gorman, AM;Samali, A (2002) Cellular longevity: role of apoptosis and replicative senescence. NEW YORK: Reviews [Details]
(2008) Mouse induced pluripotent stem cells.
Geoghegan, E;Byrnes, L (2008) Mouse induced pluripotent stem cells. BILBAO: Reviews [DOI] [Details]
(2008) Mouse induced pluripotent stem cells.
Geoghegan, E,Byrnes, L (2008) Mouse induced pluripotent stem cells. Reviews [DOI] [Details]
(2002) Cellular longevity: role of apoptosis and replicative senescence.
Bree, RT,Stenson-Cox, C,Grealy, M,Byrnes, L,Gorman, AM,Samali, A (2002) Cellular longevity: role of apoptosis and replicative senescence. Reviews [Details]

Committees

  Committee Function From / To
IUA Irish Universities Association Deans of Graduate Studies Group (2013 - Chair /
Academic Council (2010- /
Academic Council Standing Committee (2010- /
Graduate Studies Board (2010- /
Research Committee (2012- /
Council of Deans (2012-2013) member /
Sabbatical Leave Committee (2012-2013) /
Senior Lecturer Promotion Board (2011- /
Udaras na hOllscoile (2013-2016) member /
Academic Planning & Resources committee (2013-2016) member /
Priorities subcommittee (2013-2016) member /
Standing & Strategic Planning committee (2013-2016) member /
Academic Management Team (2013- /

Professional Associations

  Association Function From / To
Irish Network of Developmental Biologists Convener 01-DEC-02 /
The Biochemical Society Member 14-FEB-90 /
British Society for Developmental Biology Member 14-FEB-02 /

Education

  Year Institution Qualification Subject
1991 UCG PhD Molecular biology
1986 UCG BSc Biochemistry

Outreach Activities

  Description

Judge, Young Scientists Exhibition, 2004-2011

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2013 Rebecca Ryan (co-supervised with Maura Grealy) PhD N
2010 Miriam Moriarty (co-supervised with Maura Grealy) PhD N
2009 Lori Hartnett (co-supervised with Maura Grealy and Catherine Nolan, UCD) PhD N
2008 Shaun O'Boyle (co-supervised with Maura Grealy) PhD N
2007 Karena McCarthy (co-supervised with Catherine Nolan, UCD) PhD N
2005 Sarah McLoughlin (co-supervised with Maura Grealy) N
2004 Ed Eivers (co-supervised with Catherine Nolan, UCD) PhD N
2003 Ronan Bree (co-supervised with Maura Grealy) PhD N
2003 Catherine Collins (co-supervised with Maria Tuohy) PhD N
2002 Deirdre O'Connor PhD N
2002 Catherine Glynn (co-supervised with Afshin Samali and Adrienne Gorman) N
2002 Audrey Kelly PhD N
2001 Elena Ayaso (co-supervised with Catherine Nolan, UCD) PhD N
2001 Kathy Gately PhD N

Current Postgraduate Students (Research)

  Student Degree Type Type
Tracy Lynskey Doctorate - Structured Ph.D (Medicine) Co-supervisor (1)

Internal Collaborators

  Name Description of Collaboration
Internal Collaborators
Dr. Maura Grealy, Pharmacology & Therapeutics

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
External Collaborators
Dr. Catherine Nolan, UCD Prof. Didier Stainier, UCSF